SCIENTIFIC LIBRARY

Clinical evidence, organized by field.

A stable, curated scientific library with direct article, DOI and legal open-access full-text links, complemented by broader literature searches.

54Clinical areas
3923Curated publications
Sep 2026Last literature update
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Curated evidence is screened for direct clinical relevance, study design and bibliographic reliability.

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Metabolic & Endocrine

Obesity Recent peer-reviewed literature

Source-audited references from the connected PDF archive. Only papers directly relevant to this topic and ketogenic therapy/ketosis are shown.

1. The impact of the ketogenic diet on the health of patients with metabolic syndrome: a scoping review

Bibliographic record reviewed for inclusion in the curated Scientific Library.

2. Ketogenic Diet in Obesity and Diabetes: A Narrative Review

Bibliographic record reviewed for inclusion in the curated Scientific Library.

3. Six- and Twelve-Month Changes in Body Composition and 24-h Energy Expenditure After a Very Low-Calorie Ketogenic Diet

Bibliographic record reviewed for inclusion in the curated Scientific Library.

4. Leptin/Adiponectin Ratio as a new multidimensional biomarker in obese patients with liver steatosis undergoing VLEKT

Bibliographic record reviewed for inclusion in the curated Scientific Library.

5. Time Exposure and Fat Mass Reduction Drive Trimethylamine N-Oxide Modulation During a Very-Low-Energy Ketogenic Therapy (VLEKT) in Women with Obesity

Bibliographic record reviewed for inclusion in the curated Scientific Library.

6. The effects of a very low-energy ketogenic therapy on body composition, gut microbiota and metabolites in overweight subjects

Bibliographic record reviewed for inclusion in the curated Scientific Library.

7. Effects of a two-week modified ketogenic diet on circulating lipoprotein subclasses, GDF15, and FGF21 in obese adults

Bibliographic record reviewed for inclusion in the curated Scientific Library.

8. The impact of very-low-calorie ketogenic diets on gut microbiota in individuals with obesity: a systematic review and meta-analysis

Bibliographic record reviewed for inclusion in the curated Scientific Library.

9. Exploring the potential of the ketogenic diet in managing metabolic syndrome

Bibliographic record reviewed for inclusion in the curated Scientific Library.

10. Effects of 1-Month Very-Low-Calorie Ketogenic Diet on 24-Hour Energy Metabolism and Body Composition

Bibliographic record reviewed for inclusion in the curated Scientific Library.

11. Low-Carbohydrate (Ketogenic) Diet in Children with Obesity: Diet Impact on Anthropometric Indicators and Metabolic Syndrome and Insulin Resistance

Bibliographic record reviewed for inclusion in the curated Scientific Library.

12. Effects of One-Month Very-Low-Calorie Ketogenic Diet on 24h Energy Metabolism

Bibliographic record reviewed for inclusion in the curated Scientific Library.

13. Advancing Obesity Management: Very Low-Energy Ketogenic Therapy (VLEKT) as an Evolution of the Traditional Ketogenic Diet

Bibliographic record reviewed for inclusion in the curated Scientific Library.

14. Epigenetic Aging Acceleration in Obesity Is Slowed Down by Nutritional Ketosis Following Very Low-Calorie Ketogenic Diet

Bibliographic record reviewed for inclusion in the curated Scientific Library.

15. Ketogenic Diet Intervention for Obesity Weight-Loss: A Narrative Review, Challenges, and Open Questions

Bibliographic record reviewed for inclusion in the curated Scientific Library.

16. The Impact of Ketogenic Nutrition on Obesity and Metabolic Health

Bibliographic record reviewed for inclusion in the curated Scientific Library.

17. Efficacy and Safety of Phase 1 of Very Low Energy Ketogenic Therapy (VLEKT) in Subjects with Obesity and Mild Renal Impairment

Bibliographic record reviewed for inclusion in the curated Scientific Library.

18. The Impact of a Very-Low-Calorie Ketogenic Diet on Monocyte Subsets of Patients with Obesity: A Pilot Study

Bibliographic record reviewed for inclusion in the curated Scientific Library.

19. An 8-Week Very Low-Calorie Ketogenic Diet (VLCKD) Alters the Landscape of Obese-Derived Small Extracellular Vesicles

Bibliographic record reviewed for inclusion in the curated Scientific Library.

20. Effects of a 12 Week Ketogenic Diet Intervention on Obese and Overweight Females with Glucose and Lipid Metabolism Disturbance

Bibliographic record reviewed for inclusion in the curated Scientific Library.

21. Nutritional Studies Evaluating Ketogenic Diets as a Treatment for Obesity and Obesity-Associated Morbidities

Bibliographic record reviewed for inclusion in the curated Scientific Library.

22. The impact of a ketogenic diet on weight loss

Bibliographic record reviewed for inclusion in the curated Scientific Library.

23. European Society for the Study of Obesity (EASO) Position Statement on Very Low-Calorie Ketogenic Diets

Bibliographic record reviewed for inclusion in the curated Scientific Library.

24. Weight loss, changes in body composition and inflammatory status after a very low-energy ketogenic therapy (VLEKT)

Bibliographic record reviewed for inclusion in the curated Scientific Library.

25. A Multi-Omics Approach to Disclose Metabolic Pathways Impacting Intestinal Permeability in Obese Patients Undergoing Very Low Calorie Ketogenic Diet

Bibliographic record reviewed for inclusion in the curated Scientific Library.

26. Metabolic Effects of Ketogenic Diets and Their Utilization in Obesity

Bibliographic record reviewed for inclusion in the curated Scientific Library.

27. Very Low-Calorie Ketogenic Diet (VLCKD) as Pre-Operative First-Line Dietary Therapy in Patients with Obesity Who Are Candidates for Bariatric Surgery

Bibliographic record reviewed for inclusion in the curated Scientific Library.

28. VLCKD in Combination with Physical Exercise Preserves Skeletal Muscle in Obesity

Bibliographic record reviewed for inclusion in the curated Scientific Library.

29. Very low-calorie ketogenic diet (VLCKD): an antihypertensive nutritional approach

Bibliographic record reviewed for inclusion in the curated Scientific Library.

30. Supplementation with medium-chain fatty acids increases body weight loss during very low-calorie ketogenic diet

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Human / clinical or translational evidence

31. Time Exposure and Fat Mass Reduction Drive Trimethylamine N-Oxide Modulation During a Very-Low-Energy Ketogenic Therapy in Women with Obesity

Original publication title: Time Exposure and Fat Mass Reduction Drive Trimethylamine N-Oxide Modulation During a Very-Low-Energy Ketogenic Therapy in Women with Obesity

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Human / clinical or translational evidence

32. Low-Carbohydrate Ketogenic Diet in Children with Obesity: Effects on Anthropometric Indicators, Metabolic Syndrome and Insulin Resistance

Original publication title: Low-Carbohydrate Ketogenic Diet in Children with Obesity: Effects on Anthropometric Indicators, Metabolic Syndrome and Insulin Resistance

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Human / clinical or translational evidence

33. Effects of One-Month Very-Low-Calorie Ketogenic Diet on 24-h Energy Expenditure

Original publication title: Effects of One-Month Very-Low-Calorie Ketogenic Diet on 24-h Energy Expenditure

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Human / clinical or translational evidence

34. Advancing Obesity Management: Very Low-Energy Ketogenic Therapy as an Evolution of the Traditional Ketogenic Diet

Original publication title: Advancing Obesity Management: Very Low-Energy Ketogenic Therapy as an Evolution of the Traditional Ketogenic Diet

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Human / clinical or translational evidence

35. Epigenetic Aging Acceleration in Obesity Is Slowed Down by Nutritional Ketosis Following VLCKD

Original publication title: Epigenetic Aging Acceleration in Obesity Is Slowed Down by Nutritional Ketosis Following VLCKD

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Review

36. Ketogenic Diet Intervention for Obesity Weight Loss: A Narrative Review, Challenges, and Open Questions

Original publication title: Ketogenic Diet Intervention for Obesity Weight Loss: A Narrative Review, Challenges, and Open Questions

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Human / clinical or translational evidence

37. Efficacy and Safety of Phase 1 Very Low-Energy Ketogenic Therapy in Subjects with Obesity and Mild Renal Impairment

Original publication title: Efficacy and Safety of Phase 1 Very Low-Energy Ketogenic Therapy in Subjects with Obesity and Mild Renal Impairment

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Human / clinical or translational evidence

38. An 8-Week Very Low-Calorie Ketogenic Diet Alters Obese-Derived Small Extracellular Vesicles and Hepatic Cell Phenotypes

Original publication title: An 8-Week Very Low-Calorie Ketogenic Diet Alters Obese-Derived Small Extracellular Vesicles and Hepatic Cell Phenotypes

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Human / clinical or translational evidence

39. Effects of a 12-Week Ketogenic Diet Intervention on Women with Overweight or Obesity and Glucose and Lipid Metabolism Disturbance

Original publication title: Effects of a 12-Week Ketogenic Diet Intervention on Women with Overweight or Obesity and Glucose and Lipid Metabolism Disturbance

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Position statement

40. Weight Loss, Changes in Body Composition and Inflammatory Status after a Very Low-Energy Ketogenic Therapy

Original publication title: Weight Loss, Changes in Body Composition and Inflammatory Status after a Very Low-Energy Ketogenic Therapy

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Human / clinical or translational evidence

41. A Multi-Omics Approach to Metabolic Pathways Impacting Intestinal Permeability in Obese Patients Undergoing VLCKD

Original publication title: A Multi-Omics Approach to Metabolic Pathways Impacting Intestinal Permeability in Obese Patients Undergoing VLCKD

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Human / clinical or translational evidence

42. Very Low-Calorie Ketogenic Diet as Pre-Operative First-Line Dietary Therapy in Patients with Obesity Candidates for Bariatric Surgery

Original publication title: Very Low-Calorie Ketogenic Diet as Pre-Operative First-Line Dietary Therapy in Patients with Obesity Candidates for Bariatric Surgery

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Human / clinical or translational evidence

43. Very Low-Calorie Ketogenic Diet: An Antihypertensive Nutritional Approach

Original publication title: Very Low-Calorie Ketogenic Diet: An Antihypertensive Nutritional Approach

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Human / clinical or translational evidence

44. Supplementation with Medium-Chain Fatty Acids Increases Body Weight Loss During a Very Low-Calorie Ketogenic Diet

Original publication title: Supplementation with Medium-Chain Fatty Acids Increases Body Weight Loss During a Very Low-Calorie Ketogenic Diet

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Human / clinical or translational evidence

45. Ketogenic Diet Combined with Moderate Aerobic Exercise in Obesity

Original publication title: Ketogenic Diet Combined with Moderate Aerobic Exercise in Obesity

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Human / clinical or translational evidence

46. Comparison of a Pre-Bariatric Surgery VLCKD and Mediterranean Diet on Weight Loss, Metabolic Parameters, and Liver Size Reduction

Original publication title: Comparison of a Pre-Bariatric Surgery VLCKD and Mediterranean Diet on Weight Loss, Metabolic Parameters, and Liver Size Reduction

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Human / clinical or translational evidence

47. Impact of a VLCKD on Handgrip Strength in Women with Obesity

Original publication title: Impact of a VLCKD on Handgrip Strength in Women with Obesity

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Human / clinical or translational evidence

48. Efficacy and Safety of Very Low-Calorie Ketogenic Diet in Patients with Overweight and Obesity

Original publication title: Efficacy and Safety of Very Low-Calorie Ketogenic Diet in Patients with Overweight and Obesity

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Human / clinical or translational evidence

49. Reduction of Cardio-Metabolic Risk and Body Weight through Ketogenic Nutritional Intervention

Original publication title: Reduction of Cardio-Metabolic Risk and Body Weight through Ketogenic Nutritional Intervention

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Human / clinical or translational evidence

50. VLCKD: A Real-Time Safety Study in Obesity

Original publication title: VLCKD: A Real-Time Safety Study in Obesity

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Human / clinical or translational evidence

51. The Ketogenic Diet: Is It an Answer for Sarcopenic Obesity?

Original publication title: The Ketogenic Diet: Is It an Answer for Sarcopenic Obesity?

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Human / clinical or translational evidence

52. Ketogenic Diet and Weight Loss: Is There an Effect on Energy Expenditure?

Original publication title: Ketogenic Diet and Weight Loss: Is There an Effect on Energy Expenditure?

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Human / clinical or translational evidence

53. Comparison of Very Low-Calorie Ketogenic Diet with a Standard Low-Calorie Diet in Obesity

Original publication title: Comparison of Very Low-Calorie Ketogenic Diet with a Standard Low-Calorie Diet in Obesity

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Real-world clinical practice

54. Adaptive Ketogenic–Mediterranean Protocol (AKMP) in Real Clinical Practice

Original publication title: Adaptive Ketogenic–Mediterranean Protocol (AKMP) in Real Clinical Practice

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Review

55. Sparing Muscle While Losing Fat: A Narrative Review of Ketogenic Diets and Lean Mass Preservation During Weight Loss.

Caturano A, Mocini E, Titi L, Leva F, Cannavaro D, Tarsitano MG, Conte C · Nutrients · 2026-09-07

Preclinical / mechanistic

56. Effects of switching from a high-fat diet to a ketogenic diet on oxidative stress, nitrosative damage, and protein glycation in rat skin.

Chylińska N, Pawlukianiec C, Malinowska D, Żendzian-Piotrowska M, Maciejczyk M · Frontiers in immunology · 2026-08-27

Systematic review / meta-analysis

57. Effects of the Mediterranean Diet, Ketogenic Diet, and Intermittent Fasting on Iron Metabolism and Iron Deficiency Risk in Adults with Obesity: A Systematic Literature Review.

La Vignera S, Condorelli R · Nutrients · 2026-08-17

Observational human study

58. Real-world experience with GLP-1 receptor agonists in adults with epilepsy following a modified atkins diet.

El Zibaoui R, McDonald TJW, Henry-Barron BJ, Vizthum D, Cervenka MC · Epilepsy research · 2026-08-14

Systematic review / meta-analysis

59. Do Ketogenic Diets Produce Greater Weight Loss than Higher-Carbohydrate Diets Under Comparable Prescribed Energy Conditions? A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

Żurawski T, Bartosiewicz A · Nutrients · 2026-08-04

Preclinical / mechanistic

60. Effect of long-term use of very low-carbohydrate Ketogenic diet on the thyroid gland and adipose tissue of adult male albino rats (biochemical and histological study).

Ibrahim RA, Elwaddah NM, Aziz NM, Yousef JE, Abd El-Aleem SAE, Saber EA · Journal of molecular histology · 2026-07-30

Preclinical / mechanistic

61. Ckmm-Cre transgenic mice maintain phenotypic and cardiac mitochondrial homeostasis during ketogenic feeding.

Dogan SA · Molecular and cellular biochemistry · 2026-07-29

Clinical trial / intervention

62. Effect of Ketogenic Diet Versus Vegan Diet on Obesity-Induced Testicular Dysfunction and Mediating Role of Gut Microbiota.

Salama SA, Hassan NH, Abdelhadi AA, Soliman EK, Soliman AHM, Malek MM, Atia RRA, Mohamed SRA, Wahid IM, Salem IM, Aldisi D, Abulmeaty MMA, Abdal-Hay A, Wahid RM · International journal of molecular sciences · 2026-07-27

Systematic review / meta-analysis

63. Dietary Interventions and Testosterone Levels in Obese Men: A Systematic Review Comparing the Mediterranean Diet, Ketogenic Diet, and Intermittent Fasting.

La Vignera S, Condorelli RA · Nutrients · 2026-07-24

Systematic review / meta-analysis

64. Ketogenic diet in adult obesity: safety, limitations, and evidence from various clinical applications.

Kacprzak U, Adamaszek N, Buczkowska A, Sochowska J, Flejszman M, Danieluk J, Wójcik J, Stochaj L, Gliński M, Dołęga-Mostowska D · Roczniki Panstwowego Zakladu Higieny · 2026-07-14

Clinical trial / intervention

65. Defining a ketone threshold for weight loss: evidence from 14 day daily β-hydroxybutyrate monitoring in 217 subjects on a ketogenic diet.

Paoli A, Cerullo G, Paoli S, Charrier D, Givralli J, Bianco A, Boccuzzo G, Belloni P, Cenci L, Moro T · Nutrition & diabetes · 2026-07-14

Randomized clinical trial

66. Very-Low-Energy Ketogenic Therapy Modulates the Metabolic-Antioxidant Axis in Patients with Obesity and Type 2 Diabetes: A Non-Randomized Clinical Trial.

Tini S, Celano S, Pigni S, De Palma E, Ozdemir HI, Raiteri T, Antonioli A, Baima J, Antoniotti V, Caputo M, Marzullo P, Prodam F · Antioxidants (Basel, Switzerland) · 2026-07-04

Preclinical / mechanistic

67. Radiographic study of mandibular alterations resulting from aketogenic diet in growing rats.

Romano SC, Martin AE, Rodríguez GM, Córdoba ML, Mir MM, Salum MK, Garat JA · Acta odontologica latinoamericana : AOL · 2026-06-30

Clinical trial / intervention

68. Intensive multimodal ketogenic metabolic therapy in glioblastoma: A clinical trial.

Phillips MCL, Thotathil Z, Haji Mohd Yasin NAB, de Groot C, Tan A, Kuper-Hommel M, Creagh LA, Ji E, Naidoo N, van Essen M, Ziad F, Moon BG, Frampton C, Jameson MB · Neuro-oncology advances · 2026-06-29

Review

69. Ketogenic Diet in Obesity and Diabetes: A Narrative Review.

An Y, Norris N, Li D, Gunton JE · Nutrients · 2026-06-20

Other

70. Very Low Energy Ketogenic Therapy Effects on Fibrosis-Dependent Metabolic Reprogramming: A Serum NMR Pilot Study.

Donghia R, Musio B, De Luca M, Balestra F, Panzetta G, Todisco S, Mastrorilli P, Coletta S, Di Chito M, Giannelli G, Gallo V, Scavo MP · Nutrients · 2026-06-17

Preclinical / mechanistic

71. Effect of the ketogenic diet on absence seizures in rats with genetic absence epilepsy.

Acikgoz NB, Toplu-Hocaoglu A, Yildirim BA, Yananli HR, Turkdogan D, Onat F · Epilepsy research · 2026-06-16

Observational human study

72. Six- and Twelve-Month Changes in Body Composition and 24-h Energy Expenditure After a Very Low-Calorie Ketogenic Diet.

Basolo A, Piaggi P, Angeli V, Fierabracci P, Bologna C, Paolucci G, Salvetti G, Chiovato L, Krakoff J, Landi A, Santini F · Obesity (Silver Spring, Md.) · 2026-06-15

Systematic review / meta-analysis

73. Ketogenic diet as a therapeutic intervention for biochemical hyperandrogenism in PCOS women with obesity or overweight: a meta-analytic study.

Maseroli E, Alfaroli C, Cirillo M, Ravelli SA, Lambrinoudaki I, Focardi M, Virgili G, Vignozzi L · Journal of endocrinological investigation · 2026-06-13

Clinical trial / intervention

74. Serum Uric Acid as a Cardiovascular Risk Marker: Differential Effects of Ketogenic Diet and Intermittent Fasting in Postmenopausal Women.

Pala B, Pennazzi L, Piscione M, Nardoianni G, Miletti G, De Mitri S, Gualtieri P, Di Renzo L, Barbato E, Tocci G · Nutrients · 2026-06-12

Observational human study

75. Personalized Combination of a Ketogenic Diet and Low-Dose Semaglutide for Cardiometabolic Health: A Retrospective Case Series.

Parker G, Morris MD, Heggie JR, Cooper-Leavitt EF, Clark CJ, Reynolds AP, Smith HA, Wendel CP, Jensen WJ, Morris TJ, Reynolds PR, Bikman BT · Journal of personalized medicine · 2026-06-12

Clinical trial / intervention

76. Fetal growth is driven by a bimodal fetal beta cell response and reshaped by a ketogenic diet in a mouse model of maternal diabetes.

Cohenshtam O, Zung A, Yu A, King H, Kotova P, Gover O, Magenheim Samuel I, Helman S, Walker MD, Ben-Zvi D, Kanarek N, Helman A · Diabetologia · 2026-06-09

Clinical trial / intervention

77. Symptom impact and safety of ketogenic therapy in adults with anorexia nervosa: a feasibility trial.

Frank GKW, Scolnick B, Beckwith C, Shott ME, Kilty S, Swindle S, Lutter M, Rho JM · Communications medicine · 2026-06-03

Clinical trial / intervention

78. Ketogenic Diets and Low Carb Diets: The Effects on the Intestinal Microbiota. A Narrative Review.

Bertuccioli A, Sisti D, Palazzi CM, Belli A, Mota JF, Mariotti E, Zonzini GB, Rocchi MBL, Di Pierro F, Moro T, Paoli A · Nutrition reviews · 2026-06-02

Other

79. Correction: Dyńka et al. Ketogenic Diets for Body Weight Loss: A Comparison with Other Diets. Nutrients 2025, 17, 965.

Dyńka D, Rodzeń Ł, Rodzeń M, Pacholak-Klimas A, Ede G, Sethi S, Łojko D, Bartoń K, Berry K, Deptuła A, Grzywacz Ż, Martin P, Unwin J, Unwin D · Nutrients · 2026-05-27

Randomized clinical trial

80. Ketogenic and Low-Carbohydrate Diets in Prostate Cancer: Metabolic Rationale, Preclinical Evidence, and Preliminary Clinical Data.

Manfrini S, Malgeri A, Mone C, Francesco LD, Pecora G, Mazzilli R, Defeudis G, Khazrai MY, Faggiano A · Journal of clinical medicine · 2026-05-20

Review

81. Dukan diet, ketogenic diet and low glycemic index diet: Biochemical basis and metabolic consequences.

Muszalska A, Gaj Z, Roczyński B, Łompieś K, Polok I, Jaworska Z, Słowikowski BK · Nutrition (Burbank, Los Angeles County, Calif.) · 2026-05-12

Preclinical / mechanistic

82. Sex-specific systemic and brain metabolic responses to a standardized ketogenic diet in mice.

Lorin C, Diaceri G, Garcia M, Logette E, Markram H, Keller D · Lab animal · 2026-05-12

Systematic review / meta-analysis

83. Effects of the Ketogenic Diet on Gonadal Hormones: A Systematic Review.

Lima M, Fabe J, Grigolon RB, Ceolin G, Palma N, Gerchman F, Brietzke E, Gomes FA · Nutrition reviews · 2026-05-12

Randomized clinical trial

84. Effects of intermittent fasting combined with a ketogenic diet versus a hypocaloric diet on metabolic outcomes in adults with type 2 diabetes mellitus: A controlled clinical study.

Barrionuevo-Burgos E, García-García RM, Muñoz L, Arreguín-Coronado A · Nutrition and health · 2026-05-08

Observational human study

85. Preoperative Very-Low-Calorie Ketogenic Diet Versus Low-Calorie Diet in Bariatric Surgery: A Prospective Comparative Study.

Rahimi F, Boschetti S, Comazzi I, Pira C, Giordano V, Gambetta A, Tarallo S, Alberini V, Naccarati A, Parasiliti-Caprino M, Ponzo V, Rosato R, Arolfo S, Morino M, Bo S · Nutrients · 2026-05-07

Clinical trial / intervention

86. The effects of ketogenic diet and calorie-restricted diet on metabolic dysfunction-associated steatotic liver disease: a retrospective study.

Sun WJ, Xing LL, Zhao SF, Ying HM · Frontiers in nutrition · 2026-05-05

Clinical trial / intervention

87. Macronutrient Composition and Genetic Background Determine the Response to a Ketogenic Diet.

Zhang Z, Moura-Assis A, Liu S, Millet A, Shaked J, Rajan D, Alwaseem H, Viscio MI, Molina H, Birsoy K, Friedman J · bioRxiv : the preprint server for biology · 2026-04-27

Clinical trial / intervention

88. Ketogenic diet modulates gut microbiota composition in an experimental model of cerebral palsy.

Dantas Alves JS, De Oliveira Melo NC, Toscano AE, Manhães-De-Castro R, Fraga Filho CX, Cruz Neto JPR, De Brito Alves JL, Muniz GS · Nutritional neuroscience · 2026-04-24

Randomized clinical trial

89. Conversion Bariatric Surgery, Ketogenic Diet, and Intermittent Fasting in Bariatric Surgery Patients with Recurrent Weight Gain: a Prospective Randomized Controlled Trial.

Şen S, Erdem NZ, Durak D · Obesity surgery · 2026-04-11

Clinical trial / intervention

90. Personalizing Obesity Treatment: Real-World Comparison of a Very-Low-Calorie Ketogenic Diet Versus a Whole-Food Mediterranean Ketogenic Diet.

Masi D, Spizzichini ML, Colonnello E, Vasquez Barahona D, Gnessi L, Gianfrilli D, Watanabe M · Metabolites · 2026-04-05

Preclinical / mechanistic

91. Divergent Liver and Kidney Metabolic Responses to Ketogenic, High-Fat, and Sucrose-Enriched Diets in Mice.

Grillo G, Vega N, Zaczek A, Selmi A, Chanon S, Vieille Marchiset A, Santillo A, Balcerczyk A, Strigini M, Pirola L · Nutrients · 2026-04-01

Other

92. A ketogenic diet for the management of binge-eating disorder: a pilot study.

Liang Y, Taylor A, Haas V, Qiu C · Eating and weight disorders : EWD · 2026-03-26

Systematic review / meta-analysis

93. Metabolic, adherence, and sustainability outcomes of plant-based low-carbohydrate and ketogenic diets: A systematic review of clinical evidence.

Mazzola G, Rondanelli M, Cabrini C, Perna S · Nutrition (Burbank, Los Angeles County, Calif.) · 2026-03-24

Clinical trial / intervention

94. Leptin/Adiponectin Ratio as a new multidimensional biomarker in obese patients with liver steatosis undergoing VLEKT: results from a pilot study.

Balestra F, Donghia R, De Luca M, Stabile D, Coletta S, Panzetta G, Palieri R, Di Chito M, De Pergola G, Giannelli G, Pesole PL, Scavo MP · Frontiers in nutrition · 2026-03-20

Observational human study

95. Corrigendum to "Very-low calorie ketogenic diet reduces central blood pressure and metabolic risk in post-menopausal women with essential hypertension and obesity: a single center, prospective, open-label clinical study" [Nutr Metab Cardiovasc (2025) 4 35 4 103838].

Pala B, Pennazzi L, Nardoianni G, Rubattu SD, Volpe M, Colao AM, Barbato E, Tocci G · Nutrition, metabolism, and cardiovascular diseases : NMCD · 2026-03-18

Other

96. Low-Carbohydrate (Ketogenic) Diet in Children with Obesity: Part 2-Hormonal Effects of the Ketogenic Diet.

Paskaleva IN, Kaleva NN, Dimcheva TD, Ivanov IS · Children (Basel, Switzerland) · 2026-03-14

Randomized clinical trial

97. Immune-modulating effects of energy-restricted ketogenic diet in women with overweight and obesity: KETO-MINOX study.

Drabińska-Fois N, Ogrodowczyk AM, Bauer W, Topolska J, Bączek N, Stenbäck V, Herzig KH, Borowicz-Skoneczny S, Romaszko J · European journal of nutrition · 2026-03-07

Randomized clinical trial

98. Very low energy ketogenic diet vs. Mediterranean diet for MASLD: Superior steatosis reduction in a randomised pilot study.

Farrell AM, Paris T, Parr EB, George ES, Howell J, Croagh C, Sutherland T, Page M, McKelvie P, Thompson AJ, Ryan M · JHEP reports : innovation in hepatology · 2026-02-19

Randomized clinical trial

99. Effects of the ketogenic-caloric restricted diet on metabolic endotoxemia and metabolic health in adults with prediabetes: A randomized controlled trial.

Jawamis A, Al-Domi H, Sarayreh NA · Nutrition (Burbank, Los Angeles County, Calif.) · 2026-01-23

Clinical trial / intervention

100. Effect of a non-energy restricted ketogenic diet on cognition in sedentary healthy young adults.

Khattak M, Habib SH, Irfan M · Physiology international · 2026-01-20

Clinical trial / intervention

101. Complementary mechanisms of high-carbohydrate diets and ketogenic diets restore adult hippocampal neurogenesis and cognitive function in high-fat diet induced obesity in mice.

Kwon H, Seo DS, Ahmad Y, Park S, Yoo J, Lee J, Bae HJ, Jang Y · The Journal of nutritional biochemistry · 2025-12-29

Randomized clinical trial

102. Ketogenic diet attenuates high fat diet induced obesity in rats: insights into hepatic and intestinal tissues.

Abo El-Magd NF, Ramadan NM, Hassan YF, Mahmoud AM, Azzam MM, Eraky SM · The Journal of nutritional biochemistry · 2025-12-13

Clinical trial / intervention

103. Link between emotional and external eating behaviors, peripheral neuropeptide Y, and β-hydroxybutyrate in participants with obesity on 12-week ketogenic diet.

Černelič-Bizjak M, Kenig S, Petelin A, Jenko-Pražnikar Z, Mohorko N · Nutrition and health · 2023-02-03

Observational human study

104. Very low-calorie ketogenic diet reduces central blood pressure and cardiometabolic risk in post-menopausal women with essential hypertension and obesity: a single-center, prospective, open-label, clinical study.

Pala B, Pennazzi L, Nardoianni G, Rubattu SD, Volpe M, Colao AM, Barbato E, Tocci G · Nutrition, metabolism, and cardiovascular diseases : NMCD · 2024-12-20

Clinical trial / intervention

105. The impact of a ketogenic diet on weight loss, metabolism, body composition and quality of life.

Hirschberger S, Effinger D, Yoncheva P, Schmid A, Weis MN, Holdt LM, Teupser D, Kreth S · iScience · 2024-10-30

Randomized clinical trial

106. Development and Pragmatic Randomized Controlled Trial of Healthy Ketogenic Diet Versus Energy-Restricted Diet on Weight Loss in Adults with Obesity.

Lim SL, Tay M, Ang SM, Wai SN, Ong KW, Neo WJ, Yap QV, Chan YH, Khoo CM · Nutrients · 2024-12-19

Clinical trial / intervention

107. Effects of the Ketogenic Diet on Microbiota Composition and Short-Chain Fatty Acids in Women with Overweight/Obesity.

Güzey Akansel M, Baş M, Gençalp C, Kahrıman M, Şahin E, Öztürk H, Gür G, Gür C · Nutrients · 2024-12-19

Other

108. A Ketogenic Diet Followed by Gradual Carbohydrate Reintroduction Restores Menstrual Cycles in Women with Polycystic Ovary Syndrome with Oligomenorrhea Independent of Body Weight Loss: Results from a Single-Center, One-Arm, Pilot Study.

Rossetti R, Strinati V, Caputi A, Risi R, Spizzichini ML, Mondo A, Spiniello L, Lubrano C, Giancotti A, Tuccinardi D, Gnessi L, Watanabe M · Metabolites · 2024-12-08

Clinical trial / intervention

109. An 8-Week Very Low-Calorie Ketogenic Diet (VLCKD) Alters the Landscape of Obese-Derived Small Extracellular Vesicles (sEVs), Redefining Hepatic Cell Phenotypes.

Balestra F, De Luca M, Panzetta G, Depalo N, Rizzi F, Mastrogiacomo R, Coletta S, Serino G, Piccinno E, Stabile D, Pesole PL, De Nunzio V, Pinto G, Cerabino N, Di Chito M, Notarnicola M, Shahini E, De Pergola G, Scavo MP · Nutrients · 2024-12-04

Randomized clinical trial

110. The effects of portfolio moderate-carbohydrate and ketogenic diets on anthropometric indices, metabolic status, and hormonal levels in overweight or obese women with polycystic ovary syndrome: a randomized controlled trial.

Sharifi M, Saber A, Moludi J, Salimi Y, Jahan-Mihan A · Nutrition journal · 2024-12-02

Observational human study

111. Ketogenic diets are associated with an elevated risk of hypertension: Insights from a cross-sectional analysis of the NHANES 2007-2018.

Qu X, Liu Y, Huang L, Wan F · International journal of cardiology. Cardiovascular risk and prevention · 2024-10-10

Preclinical / mechanistic

112. Effects of a Ketogenic Diet on the Assessment of Biochemical and Clinical Parameters in Duchenne Muscular Dystrophy: A Preclinical Investigation.

Fausto LL, Alberti A, Kades G, de Carvalho RPD, Freiberger V, Ventura L, Dias P, Zanoni EM, Soares BH, Dutra ML, Martins DF, Comim CM · Molecular neurobiology · 2024-05-31

Clinical trial / intervention

113. Gut Microbiota Modulates Fgf21 Expression and Metabolic Phenotypes Induced by Ketogenic Diet.

Wei X, Lu Y, Hong S · Nutrients · 2024-11-25

Systematic review / meta-analysis

114. Does the Ketogenic Diet Mediate Inflammation Markers in Obese and Overweight Adults? A Systematic Review and Meta-Analysis of Randomized Clinical Trials.

Rondanelli M, Gasparri C, Pirola M, Barrile GC, Moroni A, Sajoux I, Perna S · Nutrients · 2024-11-22

Clinical trial / intervention

115. Safety and Effectiveness of a 4-Week Diet on Low-Carb Ready-to-Eat Ketogenic Products as Preoperative Care Treatment in Patients Scheduled for Metabolic and Bariatric Surgery.

Santella B, Mingo M, Papp A, Rice M, Chiappetta S, Calabrese P, Calenda F, Pilone V, Schiavo L · Nutrients · 2024-11-13

Preclinical / mechanistic

116. Generalized Ketogenic Diet Induced Liver Impairment and Reduced Probiotics Abundance of Gut Microbiota in Rat.

Song G, Song D, Wang Y, Wang L, Wang W · Biology · 2024-11-04

Clinical trial / intervention

117. A very-low-calorie ketogenic diet normalises obesity-related enhanced levels of erythropoietin compared with a low-calorie diet or bariatric surgery.

Fernandez-Pombo A, Lorenzo PM, Carreira MC, Gomez-Arbelaez D, Castro AI, Primo D, Rodriguez J, Sajoux I, Baltar J, de Luis D, Bellido D, Crujeiras AB, Casanueva FF · Journal of endocrinological investigation · 2024-05-02

Other

118. Ketogenic Diet and Endocrine and Metabolic Diseases: A Bibliometric Study and Visualization Analysis.

Zhang X, Jiang Y, Cai T, Huang Z, Wu Y, Zhang J · Endocrine, metabolic & immune disorders drug targets · 2024-10-28

Clinical trial / intervention

119. Weight loss, changes in body composition and inflammatory status after a very low-energy ketogenic therapy (VLEKT): does gender matter?

Muscogiuri G, Verde L, Frias-Toral E, Reytor-González C, Annunziata G, Proganò M, Savastano S, Simancas-Racines D, Colao A, Barrea L · Journal of translational medicine · 2024-10-19

Review

120. Ketogenic Diet: A Review of Composition Diversity, Mechanism of Action and Clinical Application.

Malinowska D, Żendzian-Piotrowska M · Journal of nutrition and metabolism · 2024-10-18

Randomized clinical trial

121. Effect of weight-maintaining ketogenic diet on glycemic control and insulin sensitivity in obese T2D subjects.

Merovci A, Finley B, Hansis-Diarte A, Neppala S, Abdul-Ghani MA, Cersosimo E, Triplitt C, DeFronzo RA · BMJ open diabetes research & care · 2024-10-18

Preclinical / mechanistic

122. Alterations to the copulatory sequence in young adult male Sprague-Dawley rats administered a ketogenic diet.

Tzianabos C, Chouinard G, Martinez L · Physiology & behavior · 2024-07-27

Clinical trial / intervention

123. A multiphase very-low calorie ketogenic diet improves serum redox balance by reducing oxidative status in obese patients.

Bellanti F, Losavio F, Quiete S, Lo Buglio A, Calvanese C, Dobrakowski M, Kasperczyk A, Kasperczyk S, Vendemiale G, Cincione RI · Free radical biology & medicine · 2024-07-31

Randomized clinical trial

124. A 3-Week Ketogenic Diet Increases Skeletal Muscle Insulin Sensitivity in Individuals With Obesity: A Randomized Controlled Crossover Trial.

Luong TV, Pedersen MGB, Abild CB, Lauritsen KM, Kjærulff MLG, Møller N, Gormsen LC, Søndergaard E · Diabetes · 2024-02-28

Systematic review / meta-analysis

125. The Efficacy of Ketogenic Diets (Low Carbohydrate; High Fat) as a Potential Nutritional Intervention for Lipedema: A Systematic Review and Meta-Analysis.

Amato ACM, Amato JLS, Benitti DA · Nutrients · 2024-09-27

Preclinical / mechanistic

126. The Effects of Eating a Traditional High Fat/High Carbohydrate or a Ketogenic Diet on Sensitivity of Female Rats to Morphine.

Beltran NM, Parra AN, Serrano AP, Castillo J, Castro IM, Elsey MK, Minervini V, Serafine KM · The Journal of pharmacology and experimental therapeutics · 2024-09-18

Clinical trial / intervention

127. A New Nomenclature for the Very Low-Calorie Ketogenic Diet (VLCKD): Very Low-Energy Ketogenic Therapy (VLEKT). Ketodiets and Nutraceuticals Expert Panels: "KetoNut", Italian Society of Nutraceuticals (SINut) and the Italian Association of Dietetics and Clinical Nutrition (ADI).

Barrea L, Caprio M, Grassi D, Cicero AFG, Bagnato C, Paolini B, Muscogiuri G · Current nutrition reports · 2024-07-23

Review

128. Problems and Opportunities in the use of Bioelectrical Impedance Analysis for Assessing Body Composition During Ketogenic Diets: A Scoping Review.

Paoli A, Campa F · Current obesity reports · 2024-05-27

Review

129. Take the bull by the horns and tackle the potential downsides of the ketogenic diet.

Meng Y, Sun J, Zhang G · Nutrition (Burbank, Los Angeles County, Calif.) · 2024-05-02

Randomized clinical trial

130. Self-reported menses physiology is positively modulated by a well-formulated, energy-controlled ketogenic diet vs. low fat diet in women of reproductive age with overweight/obesity.

Kackley ML, Buga A, Brownlow ML, O'Connor A, Sapper TN, Crabtree CD, Robinson BT, Stoner JT, Decker DD, Soma L, Volek JS · PloS one · 2024-08-16

Randomized clinical trial

131. Three Weeks on a Ketogenic Diet Reduces Free Testosterone and Free Estradiol in Middle-Aged Obese Men and Women.

Svart M, Rittig N, Luong TV, Gopalasingam N, Vestergaard ET, Gormsen L, Søndergaard E, Thomsen HH, Gravholt CH · Journal of nutrition and metabolism · 2024-08-06

Randomized clinical trial

132. Intermittent fasting, calorie restriction, and a ketogenic diet improve mitochondrial function by reducing lipopolysaccharide signaling in monocytes during obesity: A randomized clinical trial.

Guevara-Cruz M, Hernández-Gómez KG, Condado-Huerta C, González-Salazar LE, Peña-Flores AK, Pichardo-Ontiveros E, Serralde-Zúñiga AE, Sánchez-Tapia M, Maya O, Medina-Vera I, Noriega LG, López-Barradas A, Rodríguez-Lima O, Mata I, Olin-Sandoval V, Torres N, Tovar AR, Velázquez-Villegas LA · Clinical nutrition (Edinburgh, Scotland) · 2024-07-05

Preclinical / mechanistic

133. BETA-HYDROXYBUTYRATE COUNTERACTS THE DELETERIOUS EFFECTS OF A SATURATED HIGH-FAT DIET ON SYNAPTIC AMPA RECEPTORS AND COGNITIVE PERFORMANCE.

Rojas R, Griñán-Ferré C, Castellanos A, Griego E, Martínez M, Navarro-López JD, Jiménez-Díaz L, Rodríguez-Álvarez J, Del Cerro DS, Castillo PE, Pallàs M, Fadó R, Casals N · bioRxiv : the preprint server for biology · 2024-07-22

Clinical trial / intervention

134. Ketogenic diet-induced bile acids protect against obesity through reduced calorie absorption.

Li X, Yang J, Zhou X, Dai C, Kong M, Xie L, Liu C, Liu Y, Li D, Ma X, Dai Y, Sun Y, Jian Z, Guo X, Lin X, Li Y, Sun L, Liu X, Jin L, Tang H, Zheng Y, Hong S · Nature metabolism · 2024-06-27

Preclinical / mechanistic

135. Metagenomic and metabolomic analysis showing the adverse risk-benefit trade-off of the ketogenic diet.

Qiu H, Kan C, Han F, Luo Y, Qu N, Zhang K, Ma Y, Hou N, Wu D, Sun X, Shi J · Lipids in health and disease · 2024-06-29

Review

136. Obesity and Obesity-Related Thyroid Dysfunction: Any Potential Role for the Very Low-Calorie Ketogenic Diet (VLCKD)?

Chapela SP, Simancas-Racines A, Ceriani F, Martinuzzi ALN, Russo MP, Zambrano AK, Simancas-Racines D, Verde L, Muscogiuri G, Katsanos CS, Frias-Toral E, Barrea L · Current nutrition reports · 2024-03-25

Other

137. Authors' reply to comments on "Very low-calorie ketogenic diet in the treatment of adaptive thermogenesis: A case report".

de Oliveira J, Stelmo IC · Nutrition (Burbank, Los Angeles County, Calif.) · 2024-02-02

Other

138. The Significant Impact of High-Fat, Low-Carbohydrate Ketogenic Diet on Serum Lipid Profile and Atherosclerotic Cardiovascular Disease Risk in Overweight and Obese Adults.

Khdher S, Mohammed S, Muhammed K, Ismael A · Cureus · 2024-04-09

Other

139. Comment on "Chronotype as a predictor of weight loss and body composition improvements in women with overweight or obesity undergoing a very low-calorie ketogenic diet (VLCKD)" clinical nutrition 2023.

Thayanne Souza Alves da Silva I, Eduarda da Silva Fidelis D, Santos de Sousa Fernandes M · Clinical nutrition (Edinburgh, Scotland) · 2023-11-29

Review

140. Effect of Ketogenic Diet on Obesity and Other Metabolic Disorders: Narrative Review.

Baylie T, Ayelgn T, Tiruneh M, Tesfa KH · Diabetes, metabolic syndrome and obesity : targets and therapy · 2024-03-21

Other

141. Higher-Level Steatosis Is Associated with a Greater Decrease in Metabolic Dysfunction-Associated Steatoic Liver Disease after Eight Weeks of a Very Low-Calorie Ketogenic Diet (VLCKD) in Subjects Affected by Overweight and Obesity.

Sila A, De Nucci S, Bonfiglio C, Di Stasi V, Cerabino N, Di Chito M, Rinaldi R, Cantalice P, Shahini E, Giannuzzi V, Pesole PL, Coletta S, Tutino NM, Piazzolla G, Cozzolongo R, Giannelli G, De Pergola G · Nutrients · 2024-03-18

Systematic review / meta-analysis

142. Effects of ketogenic diet on weight loss parameters among obese or overweight patients with polycystic ovary syndrome: a systematic review and meta-analysis of randomized controlled trails.

Xing NN, Ren F, Yang H · Food & nutrition research · 2024-03-12

Review

143. The impact of ketogenic diet on some metabolic and non-metabolic diseases: Evidence from human and animal model experiments.

Galali Y, Zebari SMS, Aj Jabbar A, Hashm Balaky H, Sadee BA, Hassanzadeh H · Food science & nutrition · 2024-01-08

Other

144. Ketogenic diet for epilepsy and obesity: Is it the same?

Tagliabue A, Armeno M, Berk KA, Guglielmetti M, Ferraris C, Olieman J, van der Louw E · Nutrition, metabolism, and cardiovascular diseases : NMCD · 2024-01-14

Guideline / consensus

145. Ketogenic nutritional therapy (KeNuT)-a multi-step dietary model with meal replacements for the management of obesity and its related metabolic disorders: a consensus statement from the working group of the Club of the Italian Society of Endocrinology (SIE)-diet therapies in endocrinology and metabolism.

Barrea L, Caprio M, Camajani E, Verde L, Perrini S, Cignarelli A, Prodam F, Gambineri A, Isidori AM, Colao A, Giorgino F, Aimaretti G, Muscogiuri G · Journal of endocrinological investigation · 2024-01-18

Other

146. Comments on "Very low-calorie ketogenic diet in the treatment of adaptive thermogenesis: A case report".

Macena ML, Silva Júnior AE, Bueno NB · Nutrition (Burbank, Los Angeles County, Calif.) · 2023-11-20

Clinical trial / intervention

147. Clinical effectiveness and cost-impact after 2 years of a ketogenic diet and virtual coaching intervention for patients with diabetes.

Strombotne KL, Lum J, Pizer SD, Figueroa S, Frakt AB, Conlin PR · Diabetes, obesity & metabolism · 2023-12-11

Randomized clinical trial

148. The Effect of a Ketogenic Diet versus Mediterranean Diet on Clinical and Biochemical Markers of Inflammation in Patients with Obesity and Psoriatic Arthritis: A Randomized Crossover Trial.

Lambadiari V, Katsimbri P, Kountouri A, Korakas E, Papathanasi A, Maratou E, Pavlidis G, Pliouta L, Ikonomidis I, Malisova S, Vlachos D, Papadavid E · International journal of molecular sciences · 2024-02-20

Review

149. [Ketogenic diet: could the results of scientific studies be misleading?].

Szendi K, Murányi E, Németh B · Orvosi hetilap · 2024-02-18

Other

150. GDF15 is a major determinant of ketogenic diet-induced weight loss.

Lu JF, Zhu MQ, Xia B, Zhang NN, Liu XP, Liu H, Zhang RX, Xiao JY, Yang H, Zhang YQ, Li XM, Wu JW · Cell metabolism · 2024-02-08

Clinical trial / intervention

151. Very low-calorie ketogenic diet in the treatment of adaptive thermogenesis: A case report.

de Oliveira J, Stelmo IC, Figueredo LS, de Freitas CC · Nutrition (Burbank, Los Angeles County, Calif.) · 2023-10-01

Preclinical / mechanistic

152. Role of insulin resistance and leptin in the effect of intermittent feeding with a high-protein ketogenic diet on body composition in rats.

Eyikudamaci G, Ege H, Ensen N, Yelmen N · Nutrition (Burbank, Los Angeles County, Calif.) · 2023-09-07

Preclinical / mechanistic

153. An 8-week ketogenic diet improves exercise endurance and liver antioxidant capacity after weight loss in obese mice.

Wang Y, Dong Y, Zhang Y, Yan J, Ren C, Ma H, Cui Z · Frontiers in nutrition · 2023-12-29

Other

154. Metabolomic Profiling of Obese Patients with Altered Intestinal Permeability Undergoing a Very Low-Calorie Ketogenic Diet.

Calabrese FM, Celano G, Riezzo G, D'Attoma B, Ignazzi A, Di Chito M, Sila A, De Nucci S, Rinaldi R, Linsalata M, Vacca M, Apa CA, De Angelis M, Giannelli G, De Pergola G, Russo F · Nutrients · 2023-12-07

Randomized clinical trial

155. The effect of a ketogenic diet on weight loss in CKD: a randomized controlled trial in obese stage G1-3a CKD patients.

Zoccali C, Bellizzi V, Minutolo R, Mallamaci F, Conte G, De Nicola L · Clinical kidney journal · 2023-07-18

Systematic review / meta-analysis

156. The effects of the ketogenic diet for the management of type 2 diabetes mellitus: A systematic review and meta-analysis of recent studies.

Choy KYC, Louie JCY · Diabetes & metabolic syndrome · 2023-11-15

Other

157. Very low-calorie ketogenic diet: A valuable and fashionable nutritional therapy. When could it become dangerous?

Gorini S, Armani A, Caprio M · Diabetes/metabolism research and reviews · 2023-07-19

Observational human study

158. Effects of a two meals-a-day ketogenic diet on newly diagnosed obese patients with type 2 diabetes mellitus: A retrospective observational study.

Li S, Yuan S, Lin G, Zhang J · Medicine · 2023-11-01

Other

159. Obesity control and liver health in breast cancer: Normalized hepatic elasticity after ketogenic diet.

Georgiev A, Chervenkov L, Koleva D, Anastasova V · Heliyon · 2023-09-26

Review

160. Effects of ketone bodies on energy expenditure, substrate utilization, and energy intake in humans.

Fernández-Verdejo R, Mey JT, Ravussin E · Journal of lipid research · 2023-09-11

Preclinical / mechanistic

161. The ketogenic diet promotes triacylglycerol recycling in white adipose tissue and uncoupled fat oxidation in brown adipose tissue, but does not reduce adiposity in rats.

Da Eira D, Jani S, Stefanovic M, Ceddia RB · The Journal of nutritional biochemistry · 2023-07-06

Clinical trial / intervention

162. Sex-specific differences in metabolic hormone and adipose tissue dynamics induced by moderate low-carbohydrate and ketogenic diet.

Smolensky I, Zajac-Bakri K, Odermatt TS, Brégère C, Cryan JF, Guzman R, Timper K, Inta D · Scientific reports · 2023-09-30

Randomized clinical trial

163. Adherence to ketogenic diet in lifestyle interventions in adults with overweight or obesity and type 2 diabetes: a scoping review.

Li S, Du Y, Meireles C, Sharma K, Qi L, Castillo A, Wang J · Nutrition & diabetes · 2023-09-14

Preclinical / mechanistic

164. Ketone ester administration improves glycemia in obese mice.

Tabatabaei Dakhili SA, Yang K, Locatelli CAA, Saed CT, Greenwell AA, Chan JSF, Chahade JJ, Scharff J, Al-Imarah S, Eaton F, Crawford PA, Gopal K, Mulvihill EE, Ussher JR · American journal of physiology. Cell physiology · 2023-08-14

Preclinical / mechanistic

165. Normal diet ameliorates obesity more safely and effectively than ketogenic diet does in high-fat diet-induced obesity mouse based on gut microbiota and lipid metabolism.

Dong Y, Song H, J Holmes A, Yan J, Ren C, Zhang Y, Zhao W, Yuan J, Cheng Y, Raubenheimer D, Cui Z · International journal of food sciences and nutrition · 2023-07-20

Observational human study

166. Efficacy, feasibility and tolerability of ketogenic diet for the treatment of poor response to bariatric surgery.

Vinciguerra F, Longhitano S, Carrubba N, Piazza L, Di Stefano C, Arpi ML, Baratta R, Hagnäs M, Frittitta L · Journal of endocrinological investigation · 2023-02-21

Randomized clinical trial

167. Short- and long-term effects of very low- and low-calorie ketogenic diets on metabolism and cardiometabolic risk factors: a narrative review.

Gaspa G, Naciu AM, DI Rosa C, Lattanzi G, Beato I, Micheli V, Turriziani C, Khazrai YM, Cesareo R · Minerva endocrinology · 2022-10-26

Clinical trial / intervention

168. Effects of a Very-Low-Calorie Ketogenic Diet on the Fecal and Urinary Volatilome in an Obese Patient Cohort: A Preliminary Investigation.

Celano G, Calabrese FM, Riezzo G, D'Attoma B, Ignazzi A, Di Chito M, Sila A, De Nucci S, Rinaldi R, Linsalata M, Vacca M, Apa CA, Angelis M, Giannelli G, De Pergola G, Russo F · Nutrients · 2023-08-28

Clinical trial / intervention

169. Low-Calorie Ketogenic Diet: Potential Application in the Treatment of Polycystic Ovary Syndrome in Adolescents.

Calcaterra V, Cena H, Sottotetti F, Hruby C, Madini N, Zelaschi N, Zuccotti G · Nutrients · 2023-08-15

Randomized clinical trial

170. A comparison of the portfolio low-carbohydrate diet and the ketogenic diet in overweight and obese women with polycystic ovary syndrome: study protocol for a randomized controlled trial.

Najafabadi MS, Moludi J, Salimi Y, Saber A · Trials · 2023-08-09

Other

171. Ketogenic diets for obesity-hypoventilation syndrome? Interesting physiology but a long way to go.

Cayanan EA, Grunstein RR · Respirology (Carlton, Vic.) · 2023-07-02

Randomized clinical trial

172. Ketogenic diet acutely improves gas exchange and sleep apnoea in obesity hypoventilation syndrome: A non-randomized crossover study.

Osman A, Gu C, Kim DE, Duan D, Barron B, Pham LV, Polotsky VY, Jun JC · Respirology (Carlton, Vic.) · 2023-05-28

Review

173. Effects of very low carbohydrate ketogenic diets on skeletal health.

Best CM, Hsu S · Current opinion in endocrinology, diabetes, and obesity · 2023-05-02

Review

174. Effects of very low-calorie ketogenic diet on hypothalamic-pituitary-adrenal axis and renin-angiotensin-aldosterone system.

Barrea L, Verde L, Camajani E, Šojat AS, Marina L, Savastano S, Colao A, Caprio M, Muscogiuri G · Journal of endocrinological investigation · 2023-04-05

Other

175. Can the ketogenic diet improve our dreams? Effect of very low-calorie ketogenic diet (VLCKD) on sleep quality.

Barrea L, Verde L, Di Lorenzo C, Savastano S, Colao A, Muscogiuri G · Journal of translational medicine · 2023-07-18

Review

176. The Effects of Ketogenic Diet on Insulin Sensitivity and Weight Loss, Which Came First: The Chicken or the Egg?

Paoli A, Bianco A, Moro T, Mota JF, Coelho-Ravagnani CF · Nutrients · 2023-07-12

Clinical trial / intervention

177. Efficacy, safety and tolerability of very low-calorie ketogenic diet in obese women with fibromyalgia: a pilot interventional study.

Ciaffi J, Lisi L, Mari A, Mancarella L, Brusi V, Pignatti F, Ricci S, Vitali G, Stefanelli N, Assirelli E, Neri S, Naldi S, Faldini C, Ursini F · Frontiers in nutrition · 2023-07-12

Observational human study

178. Chronotype as a predictor of weight loss and body composition improvements in women with overweight or obesity undergoing a very low-calorie ketogenic diet (VLCKD).

Verde L, Barrea L, Docimo A, Savastano S, Colao A, Muscogiuri G · Clinical nutrition (Edinburgh, Scotland) · 2023-05-19

Clinical trial / intervention

179. Association between ß-Hydroxybutyrate Plasma Concentrations after Hypocaloric Ketogenic Diets and Changes in Body Composition.

Martins C, Nymo S, Aukan MI, Roekenes JA, Coutinho SR, Hunter GR, Gower BA · The Journal of nutrition · 2023-05-12

Randomized clinical trial

180. Efficacy of very low-calorie ketogenic diet with the Pronokal® method in obese women with polycystic ovary syndrome: a 16-week randomized controlled trial.

Pandurevic S, Mancini I, Mitselman D, Magagnoli M, Teglia R, Fazzeri R, Dionese P, Cecchetti C, Caprio M, Moretti C, Sicinska J, Agostini A, Gazineo D, Godino L, Sajoux I, Fanelli F, Meriggiola CM, Pagotto U, Gambineri A · Endocrine connections · 2023-06-12

Randomized clinical trial

181. Effects of Hypocaloric Low-Fat, Ketogenic, and Ketogenic and Ketone Supplement Diets on Aldosterone and Renin.

Belany P, Kackley ML, Zhao S, Kluwe B, Buga A, Crabtree CD, Nedungadi D, Kline D, Brock G, Simonetti OP, Volek JS, Joseph JJ · The Journal of clinical endocrinology and metabolism · 2022-08-11

Other

182. The Effects of a Very-Low-Calorie Ketogenic Diet on the Intestinal Barrier Integrity and Function in Patients with Obesity: A Pilot Study.

Linsalata M, Russo F, Riezzo G, D'Attoma B, Prospero L, Orlando A, Ignazzi A, Di Chito M, Sila A, De Nucci S, Rinaldi R, Giannelli G, De Pergola G · Nutrients · 2023-05-30

Systematic review / meta-analysis

183. Effects of ketogenic diet on health outcomes: an umbrella review of meta-analyses of randomized clinical trials.

Patikorn C, Saidoung P, Pham T, Phisalprapa P, Lee YY, Varady KA, Veettil SK, Chaiyakunapruk N · BMC medicine · 2023-05-25

Clinical trial / intervention

184. Hepatokines, bile acids and ketone bodies are novel Hormones regulating energy homeostasis.

Garruti G, Baj J, Cignarelli A, Perrini S, Giorgino F · Frontiers in endocrinology · 2023-05-19

Clinical trial / intervention

185. The effect of isocaloric, energy-restrictive, KETOgenic diet on metabolism, inflammation, nutrition deficiencies and oxidative stress in women with overweight and obesity (KETO-MINOX): Study protocol.

Drabińska N, Romaszko J, White P · PloS one · 2023-05-08

Other

186. Ketogenic diet in children and adolescents: The effects on growth and nutritional status.

Corsello A, Trovato CM, Di Profio E, Cardile S, Campoy C, Zuccotti G, Verduci E, Diamanti A · Pharmacological research · 2023-04-22

Other

187. Short-time effects of ketogenic diet or modestly hypocaloric Mediterranean diet on overweight and obese women with polycystic ovary syndrome.

Cincione IR, Graziadio C, Marino F, Vetrani C, Losavio F, Savastano S, Colao A, Laudisio D · Journal of endocrinological investigation · 2022-11-19

Preclinical / mechanistic

188. Sex-Specific Effects on Total Body Fat Gain with 4-Week Daily Dosing of Raspberry Ketone [4-(4-Hydroxyphenyl)-2-butanone] and Ketogenic Diet in Mice.

Hao L, Bello NT · Nutrients · 2023-03-28

Systematic review / meta-analysis

189. Metabolic Effects of Ketogenic Diets and Their Utilization in Obesity Management: A Systematic Review.

Malhotra V, Sawal A · Cureus · 2023-03-26

Observational human study

190. Positive effects of ketogenic diet on weight control in children with obesity due to Prader-Willi syndrome.

Teke Kısa P, Güzel O, Arslan N, Demir K · Clinical endocrinology · 2022-12-25

Other

191. Ketogenic Diet Applied in Weight Reduction of Overweight and Obese Individuals with Progress Prediction by Use of the Modified Wishnofsky Equation.

Markovikj G, Knights V, Kljusurić JG · Nutrients · 2023-02-12

Clinical trial / intervention

192. Effect of Low-Carbohydrate Diet on Beta-Hydroxybutyrate Ketogenesis Metabolic Stimulation and Regulation of NLRP3 Ubiquitination in Obese Saudi Women.

Binobead MA, Aldakhilallah AH, Alsedairy SA, Al-Harbi LN, Al-Qahtani WH, Alshammari GM · Nutrients · 2023-02-05

Systematic review / meta-analysis

193. Effects of the ketogenic diet on bone health: A systematic review.

Garofalo V, Barbagallo F, Cannarella R, Calogero AE, La Vignera S, Condorelli RA · Frontiers in endocrinology · 2023-02-02

Clinical trial / intervention

194. Very low-calorie ketogenic diet rapidly augments testosterone levels in non-diabetic obese subjects.

Cignarelli A, Santi D, Genchi VA, Conte E, Giordano F, Di Leo S, Natalicchio A, Laviola L, Giorgino F, Perrini S · Andrology · 2022-12-14

Systematic review / meta-analysis

195. Ketogenic state improves testosterone serum levels-results from a systematic review and meta-analysis.

Furini C, Spaggiari G, Simoni M, Greco C, Santi D · Endocrine · 2022-09-23

Clinical trial / intervention

196. Predictors of weight loss in patients with obesity treated with a Very Low-Calorie Ketogenic Diet.

Ernesti I, Baratta F, Watanabe M, Risi R, Camajani E, Persichetti A, Tuccinardi D, Mariani S, Lubrano C, Genco A, Spera G, Gnessi L, Basciani S · Frontiers in nutrition · 2023-01-25

Clinical trial / intervention

197. Supplementation with medium-chain fatty acids increases body weight loss during very low-calorie ketogenic diet: a retrospective analysis in a real-life setting.

Vetrani C, Verde L, Savastano S, Colao A, Muscogiuri G, Barrea L · Journal of translational medicine · 2023-01-16

Clinical trial / intervention

198. Ketogenic Diet Combined with Moderate Aerobic Exercise Training Ameliorates White Adipose Tissue Mass, Serum Biomarkers, and Hepatic Lipid Metabolism in High-Fat Diet-Induced Obese Mice.

Yan J, Ren C, Dong Y, Wali JA, Song H, Zhang Y, Zhang H, Kou G, Raubenheimer D, Cui Z · Nutrients · 2023-01-03

Other

199. Phase angle as biomarker of inflammatory changes during very low-calorie ketogenic diet.

Barrea L, Muscogiuri G, Savastano S · International journal of obesity (2005) · 2022-08-24

Randomized clinical trial

200. Clinical and nutritional management of very-low-calorie ketogenic diet (VLCKD) in patients with psoriasis and obesity: a practical guide for the nutritionist.

Barrea L, Caprio M, Camajani E, Verde L, Elce A, Frias-Toral E, Ceriani F, Cucalón G, Garcia-Velasquez E, El Ghoch M, Colao A, Savastano S, Muscogiuri G · Critical reviews in food science and nutrition · 2022-06-02

Clinical trial / intervention

201. Could very low-calorie ketogenic diets turn off low grade inflammation in obesity? Emerging evidence.

Barrea L, Caprio M, Watanabe M, Cammarata G, Feraco A, Muscogiuri G, Verde L, Colao A, Savastano S · Critical reviews in food science and nutrition · 2022-04-04

Other

202. The Antioxidant Potential of the Mediterranean Diet as a Predictor of Weight Loss after a Very Low-Calorie Ketogenic Diet (VLCKD) in Women with Overweight and Obesity.

Verde L, Dalamaga M, Capó X, Annunziata G, Hassapidou M, Docimo A, Savastano S, Colao A, Muscogiuri G, Barrea L · Antioxidants (Basel, Switzerland) · 2022-12-22

Clinical trial / intervention

203. Ketogenic Diet and Vitamin D Metabolism: A Review of Evidence.

Detopoulou P, Papadopoulou SK, Voulgaridou G, Dedes V, Tsoumana D, Gioxari A, Gerostergios G, Detopoulou M, Panoutsopoulos GI · Metabolites · 2022-12-19

Clinical trial / intervention

204. Ketogenic Diet Increases Serum and White Adipose Tissue SIRT1 Expression in Mice.

Tozzi R, Campolo F, Baldini E, Venneri MA, Lubrano C, Ulisse S, Gnessi L, Mariani S · International journal of molecular sciences · 2022-12-13

Observational human study

205. Reduced COVID-19 severity elicited by weight loss from a medically supervised ketogenic diet in a geographically diverse ambulatory population with type 2 diabetes and obesity.

Volk BM, Roberts CGP, VanTieghem M, George MP, Adams RN, Athinarayanan SJ, McKenzie AL · BMJ nutrition, prevention & health · 2022-07-01

Observational human study

206. Comparison of a pre-bariatric surgery very low-calorie ketogenic diet and the Mediterranean diet effects on weight loss, metabolic parameters, and liver size reduction.

Erdem NZ, Ozelgun D, Taskin HE, Avsar FM · Scientific reports · 2022-11-30

Preclinical / mechanistic

207. The Effect of the Restrictive Ketogenic Diet on the Body Composition, Haematological and Biochemical Parameters, Oxidative Stress and Advanced Glycation End-Products in Young Wistar Rats with Diet-Induced Obesity.

Drabińska N, Juśkiewicz J, Wiczkowski W · Nutrients · 2022-11-13

Other

208. Dynamics of Gut Microbiota and Clinical Variables after Ketogenic and Mediterranean Diets in Drug-Naïve Patients with Type 2 Diabetes Mellitus and Obesity.

Deledda A, Palmas V, Heidrich V, Fosci M, Lombardo M, Cambarau G, Lai A, Melis M, Loi E, Loviselli A, Manzin A, Velluzzi F · Metabolites · 2022-11-10

Other

209. Corrigendum: Very low calorie ketogenic diet combined with physical interval training for preserving muscle mass during weight loss in sarcopenic obesity: A pilot study.

Camajani E, Feraco A, Proietti S, Basciani S, Barrea L, Armani A, Lombardo M, Gnessi L, Caprio M · Frontiers in nutrition · 2022-11-08

Preclinical / mechanistic

210. Ketogenic diet-induced weight loss occurs independent of housing temperature and is followed by hyperphagia and weight regain after cessation in mice.

Weber A, Medak KD, Townsend LK, Wright DC · The Journal of physiology · 2022-09-25

Preclinical / mechanistic

211. Ketogenic diet administration to mice after a high-fat-diet regimen promotes weight loss, glycemic normalization and induces adaptations of ketogenic pathways in liver and kidney.

Nasser S, Solé T, Vega N, Thomas T, Balcerczyk A, Strigini M, Pirola L · Molecular metabolism · 2022-08-20

Randomized clinical trial

212. Does exercise during a ketogenic diet effectively alter appetite sensation, appetite-regulating hormones, and body composition?

Valinejad A, Khodaei K · Experimental biology and medicine (Maywood, N.J.) · 2022-08-03

Clinical trial / intervention

213. Activation of G protein-coupled receptors by ketone bodies: Clinical implication of the ketogenic diet in metabolic disorders.

Spigoni V, Cinquegrani G, Iannozzi NT, Frigeri G, Maggiolo G, Maggi M, Parello V, Dei Cas A · Frontiers in endocrinology · 2022-10-20

Randomized clinical trial

214. Mediterranean Diet versus Very Low-Calorie Ketogenic Diet: Effects of Reaching 5% Body Weight Loss on Body Composition in Subjects with Overweight and with Obesity-A Cohort Study.

Di Rosa C, Lattanzi G, Spiezia C, Imperia E, Piccirilli S, Beato I, Gaspa G, Micheli V, De Joannon F, Vallecorsa N, Ciccozzi M, Defeudis G, Manfrini S, Khazrai YM · International journal of environmental research and public health · 2022-10-11

Other

215. Does the Ketogenic Diet Improve the Quality of Ovarian Function in Obese Women?

Magagnini MC, Condorelli RA, Cimino L, Cannarella R, Aversa A, Calogero AE, La Vignera S · Nutrients · 2022-10-06

Case report / case series

216. Ketogenic diet may be a new approach to treatment stress urinary incontinence in obese elderly women: report of five cases.

Sun Y, Chen H, Bai Y, Zhang T, Bai W, Jiang B · BMC women's health · 2022-10-04

Review

217. The gut microbiome as possible mediator of the beneficial effects of very low calorie ketogenic diet on type 2 diabetes and obesity: a narrative review.

Defeudis G, Rossini M, Khazrai YM, Pipicelli AMV, Brucoli G, Veneziano M, Strollo F, AMD-SID-SIEDP-Lifestyle Study Group Lazio, Bellia A, Bitterman O, Lauro D, Mora D, Santarelli E · Eating and weight disorders : EWD · 2022-07-01

Systematic review / meta-analysis

218. VLCD versus VLCKD for obese male patients with hypogonadism: considerations about the recent systematic review and consensus statement published by the Italian Society of Endocrinology.

Onfiani G · Eating and weight disorders : EWD · 2022-05-17

Clinical trial / intervention

219. Very low calorie ketogenic diet combined with physical interval training for preserving muscle mass during weight loss in sarcopenic obesity: A pilot study.

Camajani E, Feraco A, Proietti S, Basciani S, Barrea L, Armani A, Lombardo M, Gnessi L, Caprio M · Frontiers in nutrition · 2022-09-29

Clinical trial / intervention

220. Phase angle as an easy diagnostic tool for the nutritionist in the evaluation of inflammatory changes during the active stage of a very low-calorie ketogenic diet.

Barrea L, Muscogiuri G, Aprano S, Vetrani C, de Alteriis G, Varcamonti L, Verde L, Colao A, Savastano S · International journal of obesity (2005) · 2022-05-25

Clinical trial / intervention

221. The effect of long-term ketogenic diet on serum adiponectin and insulin-like growth factor-1 levels in mice.

Widiatmaja DM, Lutvyani A, Sari DR, Kurniasari H, Meiliana ID, Fasitasari M, Yamaoka Y, Rejeki PS · Journal of basic and clinical physiology and pharmacology · 2021-10-21

Randomized clinical trial

222. Ketogenic Diet for Preoperative Weight Reduction in Bariatric Surgery: A Narrative Review.

Colangeli L, Gentileschi P, Sbraccia P, Guglielmi V · Nutrients · 2022-08-31

Other

223. Influence of Nutritional Ketosis Achieved through Various Methods on Plasma Concentrations of Brain Derived Neurotropic Factor.

Kackley ML, Buga A, Crabtree CD, Sapper TN, McElroy CA, Focht BC, Kraemer WJ, Volek JS · Brain sciences · 2022-08-27

Clinical trial / intervention

224. A Novel Multiphase Modified Ketogenic Diet: An Effective and Safe Tool for Weight Loss in Chinese Obese Patients.

Wu W, Zhou Q, Yuan P, Qiao D, Deng S, Cheng H, Ren Y · Diabetes, metabolic syndrome and obesity : targets and therapy · 2022-08-17

Review

225. Epigenome Modulation Induced by Ketogenic Diets.

Ungaro P, Nettore IC, Franchini F, Palatucci G, Muscogiuri G, Colao A, Macchia PE · Nutrients · 2022-08-08

Randomized clinical trial

226. Effect of a ketogenic diet on pain and quality of life in patients with lipedema: The LIPODIET pilot study.

Sørlie V, De Soysa AK, Hyldmo ÅA, Retterstøl K, Martins C, Nymo S · Obesity science & practice · 2022-04-21

Randomized clinical trial

227. A technology assisted precision ketogenic diet intervention for cardio-renal-metabolic health in overweight or obese adults: Protocol for a randomized controlled trial.

Du Y, Wang J, Li S, Dennis B, Meireles C, Siddiqui N, Patel D, Gelfond J, Li C, Faruqui SH, Alaeddini A, Drel V, Tumova J, Ye H, Montellano R, Armaiz-Pena G, Sharma K · Contemporary clinical trials · 2022-07-07

Clinical trial / intervention

228. Effects of a ketogenic diet in women with PCOS with different uric acid concentrations: a prospective cohort study.

Yang M, Bai W, Jiang B, Wang Z, Wang X, Sun Y, Liu F, Cui G, Song X, Li J, Wu F · Reproductive biomedicine online · 2022-04-02

Clinical trial / intervention

229. Western and ketogenic diets in neurological disorders: can you tell the difference?

Habashy KJ, Ahmad F, Ibeh S, Mantash S, Kobeissy F, Issa H, Habis R, Tfaily A, Nabha S, Harati H, Reslan MA, Yehya Y, Barsa C, Shaito A, Zibara K, El-Yazbi AF, Kobeissy FH · Nutrition reviews · 2022-02-17

Clinical trial / intervention

230. An isoproteic cocoa butter-based ketogenic diet fails to improve glucose homeostasis and promote weight loss in obese mice.

Greenwell AA, Saed CT, Tabatabaei Dakhili SA, Ho KL, Gopal K, Chan JSF, Kaczmar OO, Dyer SA, Eaton F, Lopaschuk GD, Al Batran R, Ussher JR · American journal of physiology. Endocrinology and metabolism · 2022-05-16

Other

231. Changes in Adiposity and Cerebrospinal Fluid Biomarkers Following a Modified Mediterranean Ketogenic Diet in Older Adults at Risk for Alzheimer's Disease.

Brinkley TE, Leng I, Register TC, Neth BJ, Zetterberg H, Blennow K, Craft S · Frontiers in neuroscience · 2022-06-02

Observational human study

232. The effect of low-carbohydrate ketogenic diet in the management of obesity compared with low caloric, low-fat diet.

Al Aamri KS, Alrawahi AH, Al Busaidi N, Al Githi MS, Al Jabri K, Al Balushi F, Ronquillo-Talara R, Al Balushi S, Waly M · Clinical nutrition ESPEN · 2022-02-24

Preclinical / mechanistic

233. Beta-Hydroxybutyrate Suppresses Hepatic Production of the Ghrelin Receptor Antagonist LEAP2.

Holm S, Husted AS, Skov LJ, Morville TH, Hagemann CA, Jorsal T, Dall M, Jakobsen A, Klein AB, Treebak JT, Knop FK, Schwartz TW, Clemmensen C, Holst B · Endocrinology · 2021-11-29

Review

234. Possible Nonneurological Health Benefits of Ketogenic Diet: Review of Scientific Reports over the Past Decade.

Daria Gołąbek K, Regulska-Ilow B · Journal of obesity · 2022-05-27

Observational human study

235. KetoCycle mobile app for ketogenic diet: a retrospective study of weight loss and engagement.

Valinskas S, Aleknavicius K, Jonusas J · BMC nutrition · 2022-05-02

Clinical trial / intervention

236. Short-Term Ketogenic Diet Induces a Molecular Response That Is Distinct From Dietary Protein Restriction.

Kalafut KC, Mitchell SJ, MacArthur MR, Mitchell JR · Frontiers in nutrition · 2022-03-30

Randomized clinical trial

237. Use of an mHealth Ketogenic Diet App Intervention and User Behaviors Associated With Weight Loss in Adults With Overweight or Obesity: Secondary Analysis of a Randomized Clinical Trial.

Falkenhain K, Locke SR, Lowe DA, Lee T, Singer J, Weiss EJ, Little JP · JMIR mHealth and uHealth · 2022-03-14

Other

238. Beneficial Effects of the Very-Low-Calorie Ketogenic Diet on the Symptoms of Male Accessory Gland Inflammation.

Condorelli RA, Aversa A, Basile L, Cannarella R, Mongioì LM, Cimino L, Perelli S, Caprio M, Cimino S, Calogero AE, La Vignera S · Nutrients · 2022-03-04

Randomized clinical trial

239. Low-Calorie Ketogenic Diet with Continuous Positive Airway Pressure to Alleviate Severe Obstructive Sleep Apnea Syndrome in Patients with Obesity Scheduled for Bariatric/Metabolic Surgery: a Pilot, Prospective, Randomized Multicenter Comparative Study.

Schiavo L, Pierro R, Asteria C, Calabrese P, Di Biasio A, Coluzzi I, Severino L, Giovanelli A, Pilone V, Silecchia G · Obesity surgery · 2021-11-20

Other

240. A multiphase dietetic protocol incorporating an improved ketogenic diet enhances weight loss and alters the gut microbiome of obese people.

Yuan W, Lu W, Wang H, Wu W, Zhou Q, Chen Y, Lee YK, Zhao J, Zhang H, Chen W · International journal of food sciences and nutrition · 2021-08-06

Clinical trial / intervention

241. KETOgenic diet therapy in patients with HEPatocellular adenoma: study protocol of a matched interventional cohort study.

Oudmaijer CAJ, Berk KA, van der Louw EJTM, de Man R, van der Lelij AJ, Hoeijmakers JHJ, IJzermans J · BMJ open · 2022-02-15

Review

242. [Effect of ketogenic diet on obesity asthma].

Kong LD, Wu QP · Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases · 2022-02-09

Preclinical / mechanistic

243. Is a Ketogenic Diet Superior to a High-Fat, High-Cholesterol Diet Regarding Testicular Function and Spermatogenesis?

Liu CY, Chang TC, Lin SH, Tsao CW · Frontiers in nutrition · 2022-02-10

Systematic review / meta-analysis

244. Effect of a very low-carbohydrate ketogenic diet vs recommended diets in patients with type 2 diabetes: a meta-analysis.

Rafiullah M, Musambil M, David SK · Nutrition reviews · 2021-08-03

Observational human study

245. Role of nutritional ketosis in the improvement of metabolic parameters following bariatric surgery.

Pindozzi F, Socci C, Bissolati M, Marchi M, Devecchi E, Saibene A, Conte C · World journal of diabetes · 2021-05-08

Review

246. A Review of Ketogenic Diet and Lifestyle.

McGaugh E, Barthel B · Missouri medicine · 2022-08-29

Clinical trial / intervention

247. Can the Ketogenic diet lead to Wernicke's encephalopathy?

Javaid S, Lindenberg A, Srinivasan R · Journal of pediatric rehabilitation medicine · 2022-02-12

Systematic review / meta-analysis

248. The Effect of Ketogenic Diet on Weight Loss in Adult Patients with Cancer: A Systematic Review and Meta-Analysis of Controlled Clinical Trials.

Taftian M, Beigrezaei S, Arabi V, Salehi-Abargouei A · Nutrition and cancer · 2022-02-07

Other

249. Effect of very low-calorie ketogenic diet in combination with omega-3 on inflammation, satiety hormones, body composition, and metabolic markers. A pilot study in class I obese subjects.

Rondanelli M, Perna S, Ilyas Z, Peroni G, Bazire P, Sajuox I, Maugeri R, Nichetti M, Gasparri C · Endocrine · 2021-09-16

Review

250. Very low-calorie ketogenic diet (VLCKD) in patients with psoriasis and obesity: an update for dermatologists and nutritionists.

Barrea L, Megna M, Cacciapuoti S, Frias-Toral E, Fabbrocini G, Savastano S, Colao A, Muscogiuri G · Critical reviews in food science and nutrition · 2020-09-24

Systematic review / meta-analysis

251. The Role of the Gut Microbiota on the Beneficial Effects of Ketogenic Diets.

Attaye I, van Oppenraaij S, Warmbrunn MV, Nieuwdorp M · Nutrients · 2021-12-31

Preclinical / mechanistic

252. Impact of ketogenic diet and ketone diester supplementation on body weight, blood glucose, and ketones in Sprague Dawley rats fed over two weeks.

Modica LCM, Flores-Felix K, Casachahua LJD, Asquith P, Tschiffely A, Ciarlone S, Ahlers ST · Food chemistry. Molecular sciences · 2021-06-10

Randomized clinical trial

253. Randomized Clinical Trial to Evaluate the Morphological Changes in the Adventitial Vasa Vasorum Density and Biological Markers of Endothelial Dysfunction in Subjects with Moderate Obesity Undergoing a Very Low-Calorie Ketogenic Diet.

Sánchez E, Santos MD, Nuñez-Garcia M, Bueno M, Sajoux I, Yeramian A, Lecube A · Nutrients · 2021-12-23

Systematic review / meta-analysis

254. Effect of Ketogenic Diet on Quality of Life in Adults with Chronic Disease: A Systematic Review of Randomized Controlled Trials.

Abboud M, AlAnouti F, Georgaki E, Papandreou D · Nutrients · 2021-12-14

Observational human study

255. Ketogenic Diets: Side Effects, Attitude, and Quality of Life.

Shalabi H, Alotaibi A, Alqahtani A, Alattas H, Alghamdi Z · Cureus · 2021-12-13

Clinical trial / intervention

256. Ketogenic Diet for Obese COVID-19 Patients: Is Respiratory Disease a Contraindication? A Narrative Review of the Literature on Ketogenic Diet and Respiratory Function.

Gangitano E, Tozzi R, Mariani S, Lenzi A, Gnessi L, Lubrano C · Frontiers in nutrition · 2021-12-09

Other

257. Very-Low-Calorie Ketogenic Diet: A Potential Treatment for Binge Eating and Food Addiction Symptoms in Women. A Pilot Study.

Rostanzo E, Marchetti M, Casini I, Aloisi AM · International journal of environmental research and public health · 2021-12-04

Observational human study

258. Effectiveness and Safety of a Very Low-Calorie Ketogenic Diet on Weight Regain Following Bariatric Surgery.

Correa LL, Moretti A, de Sousa PAM, Dinis L, de Souza MF, Tostes I, Nuñez-Garcia M, Sajoux I · Obesity surgery · 2021-09-24

Clinical trial / intervention

259. Effectiveness of a ketogenic diet and virtual coaching intervention for patients with diabetes: A difference-in-differences analysis.

Strombotne KL, Lum J, Ndugga NJ, Utech AE, Pizer SD, Frakt AB, Conlin PR · Diabetes, obesity & metabolism · 2021-08-19

Other

260. Effects of Mixed of a Ketogenic Diet in Overweight and Obese Women with Polycystic Ovary Syndrome.

Cincione RI, Losavio F, Ciolli F, Valenzano A, Cibelli G, Messina G, Polito R · International journal of environmental research and public health · 2021-11-27

Clinical trial / intervention

261. Effects of a Non-Energy-Restricted Ketogenic Diet on Clinical Oral Parameters. An Exploratory Pilot Trial.

Woelber JP, Tennert C, Ernst SF, Vach K, Ratka-Krüger P, Bertz H, Urbain P · Nutrients · 2021-11-25

Clinical trial / intervention

262. Can older patients adopt and maintain a ketogenic diet? An observational study in support of clinical trials in older patients.

Almodallal Y, Cook K, Lammert LM, Lee M, Le-Rademacher JG, Jatoi A · Medicine · 2020-12-15

Other

263. [The ketogenic diet: history, mechanism of action, indications and contraindications].

Ivannikova EV, Altashina MA, Troshina EA · Problemy endokrinologii · 2021-11-03

Review

264. Ketogenic Diets and Cardio-Metabolic Diseases.

Zhang W, Guo X, Chen L, Chen T, Yu J, Wu C, Zheng J · Frontiers in endocrinology · 2021-11-02

Review

265. The Role of Short-Chain Fatty Acids in Mediating Very Low-Calorie Ketogenic Diet-Infant Gut Microbiota Relationships and Its Therapeutic Potential in Obesity.

Alsharairi NA · Nutrients · 2021-10-21

Review

266. Measuring ketone bodies for the monitoring of pathologic and therapeutic ketosis.

Anderson JC, Mattar SG, Greenway FL, Lindquist RJ · Obesity science & practice · 2021-05-04

Review

267. Very-low-calorie ketogenic diet: An alternative to a pharmacological approach to improve glycometabolic and gonadal profile in men with obesity.

Mongioì LM, Cimino L, Greco E, Cannarella R, Condorelli RA, La Vignera S, Calogero AE · Current opinion in pharmacology · 2021-08-03

Clinical trial / intervention

268. Ketogenic diet as an advanced option for the management of pediatric obesity.

Favret J, Wood CT, Maradiaga Panayotti GM · Current opinion in endocrinology, diabetes, and obesity · 2021-07-17

Clinical trial / intervention

269. The Role of Very Low Calorie Ketogenic Diet in Sympathetic Activation through Cortisol Secretion in Male Obese Population.

Polito R, Messina G, Valenzano A, Scarinci A, Villano I, Monda M, Cibelli G, Porro C, Pisanelli D, Monda V, Messina A · Journal of clinical medicine · 2021-09-18

Systematic review / meta-analysis

270. Effect of a Ketogenic Diet on the Nutritional Parameters of Obese Patients: A Systematic Review and Meta-Analysis.

López-Espinoza MÁ, Chacón-Moscoso S, Sanduvete-Chaves S, Ortega-Maureira MJ, Barrientos-Bravo T · Nutrients · 2021-08-25

Clinical trial / intervention

271. Metabolic Derangement in Pediatric Patient with Obesity: The Role of Ketogenic Diet as Therapeutic Tool.

Calcaterra V, Verduci E, Pascuzzi MC, Magenes VC, Fiore G, Di Profio E, Tenuta E, Bosetti A, Todisco CF, D'Auria E, Zuccotti G · Nutrients · 2021-08-16

Clinical trial / intervention

272. Very Low-Calorie Ketogenic Diet Modulates the Autonomic Nervous System Activity through Salivary Amylase in Obese Population Subjects.

Polito R, Valenzano A, Scarinci A, Villano I, Monda M, Messina A, Cibelli G, Porro C, La Torre E, Pisanelli D, Moscatelli F, Messina G, Monda V · International journal of environmental research and public health · 2021-08-11

Review

273. A Clinical Perspective of Low Carbohydrate Ketogenic Diets: A Narrative Review.

Sukkar SG, Muscaritoli M · Frontiers in nutrition · 2021-07-12

Review

274. Ketogenic diets and appetite regulation.

Roekenes J, Martins C · Current opinion in clinical nutrition and metabolic care · 2021-04-23

Other

275. Very Low-Calorie Ketogenic Diets to Treat Patients With Obesity and Chronic Kidney Disease.

Masi D, Risi R, Basciani S, Tuccinardi D, Mariani S, Lubrano C, Gnessi L, Watanabe M · Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation · 2020-10-22

Case report / case series

276. Treating Diabetes Utilizing a Low Carbohydrate Ketogenic Diet and Intermittent Fasting Without Significant Weight Loss: A Case Report.

Gavidia K, Kalayjian T · Frontiers in nutrition · 2021-06-28

Review

277. Novel Nutritional and Dietary Approaches to Weight Loss for the Prevention of Cardiovascular Disease: Ketogenic Diet, Intermittent Fasting, and Bariatric Surgery.

Becker A, Gaballa D, Roslin M, Gianos E, Kane J · Current cardiology reports · 2021-06-03

Other

278. Epigenetic landscape in blood leukocytes following ketosis and weight loss induced by a very low calorie ketogenic diet (VLCKD) in patients with obesity.

Crujeiras AB, Izquierdo AG, Primo D, Milagro FI, Sajoux I, Jácome A, Fernandez-Quintela A, Portillo MP, Martínez JA, Martinez-Olmos MA, de Luis D, Casanueva FF · Clinical nutrition (Edinburgh, Scotland) · 2021-05-21

Clinical trial / intervention

279. Very-low-calorie ketogenic diet for the management of obesity, overweight and related disorders.

Castellana M, Biacchi E, Procino F, Casanueva FF, Trimboli P · Minerva endocrinology · 2020-11-19

Other

280. Obesity and Circulating Levels of Vitamin D before and after Weight Loss Induced by a Very Low-Calorie Ketogenic Diet.

Buscemi S, Buscemi C, Corleo D, De Pergola G, Caldarella R, Meli F, Randazzo C, Milazzo S, Barile AM, Rosafio G, Settipani V, Gurrera S, Borzì AM, Ciaccio M · Nutrients · 2021-05-27

Observational human study

281. Reduction of Cardio-Metabolic Risk and Body Weight through a Multiphasic Very-Low Calorie Ketogenic Diet Program in Women with Overweight/Obesity: A Study in a Real-World Setting.

Tragni E, Vigna L, Ruscica M, Macchi C, Casula M, Santelia A, Catapano AL, Magni P · Nutrients · 2021-05-26

Other

282. The ketogenic diet corrects metabolic hypogonadism and preserves pancreatic ß-cell function in overweight/obese men: a single-arm uncontrolled study.

La Vignera S, Cannarella R, Galvano F, Grillo A, Aversa A, Cimino L, Magagnini CM, Mongioì LM, Condorelli RA, Calogero AE · Endocrine · 2020-10-15

Review

283. Clinical Implications for Women of a Low-Carbohydrate or Ketogenic Diet With Intermittent Fasting.

Arbour MW, Stec M, Walker KC, Wika JC · Nursing for women's health · 2020-02-21

Randomized clinical trial

284. A Randomized, Controlled Trial Comparing the Impact of a Low-Calorie Ketogenic vs a Standard Low-Calorie Diet on Fat-Free Mass in Patients Receiving an Elipse™ Intragastric Balloon Treatment.

Schiavo L, De Stefano G, Persico F, Gargiulo S, Di Spirito F, Griguolo G, Petrucciani N, Fontas E, Iannelli A, Pilone V · Obesity surgery · 2020-11-20

Clinical trial / intervention

285. Sex-specific effects of ketogenic diet after pre-exposure to a high-fat, high-sugar diet in rats.

Sahagun E, Bachman BB, Kinzig KP · Nutrition, metabolism, and cardiovascular diseases : NMCD · 2020-10-09

Other

286. Effect of Very-Low-Calorie Ketogenic Diet on Psoriasis Patients: A Nuclear Magnetic Resonance-Based Metabolomic Study.

Castaldo G, Pagano I, Grimaldi M, Marino C, Molettieri P, Santoro A, Stillitano I, Romano R, Montoro P, D'Ursi AM, Rastrelli L · Journal of proteome research · 2020-11-09

Review

287. Low-carbohydrate ketogenic diets in body weight control: A recurrent plaguing issue of fad diets?

Schutz Y, Montani JP, Dulloo AG · Obesity reviews : an official journal of the International Association for the Study of Obesity · 2021-01-20

Randomized clinical trial

288. Ketogenic diet in women with polycystic ovary syndrome and liver dysfunction who are obese: A randomized, open-label, parallel-group, controlled pilot trial.

Li J, Bai WP, Jiang B, Bai LR, Gu B, Yan SX, Li FY, Huang B · The journal of obstetrics and gynaecology research · 2021-01-18

Clinical trial / intervention

289. Nutritional ketosis to treat pulmonary hypertension associated with obesity and metabolic syndrome: a case report.

Kim D, Roberts C, McKenzie A, George MP · Pulmonary circulation · 2021-02-16

Randomized clinical trial

290. Effect of a plant-based, low-fat diet versus an animal-based, ketogenic diet on ad libitum energy intake.

Hall KD, Guo J, Courville AB, Boring J, Brychta R, Chen KY, Darcey V, Forde CG, Gharib AM, Gallagher I, Howard R, Joseph PV, Milley L, Ouwerkerk R, Raisinger K, Rozga I, Schick A, Stagliano M, Torres S, Walter M, Walter P, Yang S, Chung ST · Nature medicine · 2021-01-21

Systematic review / meta-analysis

291. Effects of Combined Exercise and Low Carbohydrate Ketogenic Diet Interventions on Waist Circumference and Triglycerides in Overweight and Obese Individuals: A Systematic Review and Meta-Analysis.

Lee HS, Lee J · International journal of environmental research and public health · 2021-01-19

Other

292. Effects of Ketogenic Diet on Some Immunological Parameters.

G M Al-Allaff R, Kaydar Mohmad F · Pakistan journal of biological sciences : PJBS · 2021-09-06

Other

293. [Obesity, inflammation and COVID-19: preventive interest of ketogenic diet?].

Charlot A, Boumiza R, Roux M, Zoll J · Biologie aujourd'hui · 2021-08-16

Preclinical / mechanistic

294. The Safety of Very-long-term Intake of a Ketogenic Diet Containing Medium-chain Triacylglycerols.

Fukazawa A, Karasawa T, Yokota Y, Kondo S, Aoyama T, Terada S · Journal of oleo science · 2021-07-01

Systematic review / meta-analysis

295. European Guidelines for Obesity Management in Adults with a Very Low-Calorie Ketogenic Diet: A Systematic Review and Meta-Analysis.

Muscogiuri G, El Ghoch M, Colao A, Hassapidou M, Yumuk V, Busetto L, Obesity Management Task Force (OMTF) of the European Association for the Study of Obesity (EASO) · Obesity facts · 2021-04-21

Review

296. Implicating the effect of ketogenic diet as a preventive measure to obesity and diabetes mellitus.

Kumar S, Behl T, Sachdeva M, Sehgal A, Kumari S, Kumar A, Kaur G, Yadav HN, Bungau S · Life sciences · 2020-10-26

Other

297. The Islet De-stress Hypothesis: A potential explanation for the gluco metabolic effects of ketogenic diet.

Kalra S, Singla R, Dhawan M, Bhattacharya S, Aggarwal S · JPMA. The Journal of the Pakistan Medical Association · 2021-01-21

Clinical trial / intervention

298. [The impact on metabolic and reproductive diseases of low-carbohydrate and ketogenic diets].

Moreno-Sepúlveda J, Capponi M · Revista medica de Chile · 2019-08-22

Clinical trial / intervention

299. Very low calorie ketogenic diets in overweight and obesity treatment: Effects on anthropometric parameters, body composition, satiety, lipid profile and microbiota.

Di Rosa C, Lattanzi G, Taylor SF, Manfrini S, Khazrai YM · Obesity research & clinical practice · 2020-09-09

Other

300. Ketogenic Diet: Risks and Downfalls.

Joshi S · The Journal of nutrition · 2020-10-12

Review

301. The biochemistry of low-carbohydrate and ketogenic diets.

Feinman RD · Current opinion in endocrinology, diabetes, and obesity · 2020-08-17

Clinical trial / intervention

302. Ketogenic diet aggravates hypertension via NF-κB-mediated endothelial dysfunction in spontaneously hypertensive rats.

Guo Y, Wang X, Jia P, You Y, Cheng Y, Deng H, Luo S, Huang B · Life sciences · 2020-07-21

Clinical trial / intervention

303. Scientific evidence underlying contraindications to the ketogenic diet: An update.

Watanabe M, Tuccinardi D, Ernesti I, Basciani S, Mariani S, Genco A, Manfrini S, Lubrano C, Gnessi L · Obesity reviews : an official journal of the International Association for the Study of Obesity · 2020-07-10

Other

304. Effectiveness of a Very Low Calorie Ketogenic Diet on Testicular Function in Overweight/Obese Men.

Mongioì LM, Cimino L, Condorelli RA, Magagnini MC, Barbagallo F, Cannarella R, La Vignera S, Calogero AE · Nutrients · 2020-09-28

Clinical trial / intervention

305. A comparison of a ketogenic diet with a LowGI/nutrigenetic diet over 6 months for weight loss and 18-month follow-up.

Vranceanu M, Pickering C, Filip L, Pralea IE, Sundaram S, Al-Saleh A, Popa DS, Grimaldi KA · BMC nutrition · 2020-09-24

Case report / case series

306. Severe Metabolic Acidosis: A Case of Triple Hit with Ketogenic Diet, Vinegar, and Metformin in an Obese Patient.

Rana AM, Mansoor K, Assad S, Abouzid M, Ogu I, Bandak GSI · Case reports in nephrology · 2020-09-15

Randomized clinical trial

307. Efficacy of a 2-Month Very Low-Calorie Ketogenic Diet (VLCKD) Compared to a Standard Low-Calorie Diet in Reducing Visceral and Liver Fat Accumulation in Patients With Obesity.

Cunha GM, Guzman G, Correa De Mello LL, Trein B, Spina L, Bussade I, Marques Prata J, Sajoux I, Countinho W · Frontiers in endocrinology · 2020-09-14

Clinical trial / intervention

308. Very Low-Carbohydrate Ketogenic Diet for the Treatment of Severe Obesity and Associated Non-Alcoholic Fatty Liver Disease: The Role of Sex Differences.

D'Abbondanza M, Ministrini S, Pucci G, Nulli Migliola E, Martorelli EE, Gandolfo V, Siepi D, Lupattelli G, Vaudo G · Nutrients · 2020-09-09

Other

309. [VLCD and VLCKD in the treatment of obese people with non-insulin-dependent diabetes or prediabetes: clinical evidence and reflections.].

Fatati G · Recenti progressi in medicina · 2020-09-11

Clinical trial / intervention

310. Ketogenic diets as treatment of obesity and type 2 diabetes mellitus.

Casanueva FF, Castellana M, Bellido D, Trimboli P, Castro AI, Sajoux I, Rodriguez-Carnero G, Gomez-Arbelaez D, Crujeiras AB, Martinez-Olmos MA · Reviews in endocrine & metabolic disorders · 2020-08-18

Randomized clinical trial

311. Very-Low-Calorie Ketogenic Diets With Whey, Vegetable, or Animal Protein in Patients With Obesity: A Randomized Pilot Study.

Basciani S, Camajani E, Contini S, Persichetti A, Risi R, Bertoldi L, Strigari L, Prossomariti G, Watanabe M, Mariani S, Lubrano C, Genco A, Spera G, Gnessi L · The Journal of clinical endocrinology and metabolism · 2020-01-16

Preclinical / mechanistic

312. Exogenous Dietary Ketone Ester Decreases Body Weight and Adiposity in Mice Housed at Thermoneutrality.

Deemer SE, Davis RAH, Roberts BM, Smith DL, Koutnik AP, Poff AM, D'Agostino DP, Plaisance EP · Obesity (Silver Spring, Md.) · 2020-07-02

Other

313. Short-Term Ketogenic Diet Improves Abdominal Obesity in Overweight/Obese Chinese Young Females.

Kong Z, Sun S, Shi Q, Zhang H, Tong TK, Nie J · Frontiers in physiology · 2020-07-28

Observational human study

314. [Multidisciplinary methodology and ketogenic diet in real clinical practice: efficacy and rapidity in weight loss. Survival Analysis PROMET Lipoinflammation study].

Guzmán G, Sajoux I, Aller R, Izaola O, de Luis D · Nutricion hospitalaria · 2020-05-08

Systematic review / meta-analysis

315. Impact of a Ketogenic Diet on Metabolic Parameters in Patients with Obesity or Overweight and with or without Type 2 Diabetes: A Meta-Analysis of Randomized Controlled Trials.

Choi YJ, Jeon SM, Shin S · Nutrients · 2020-07-06

Randomized clinical trial

316. MRI estimated changes in visceral adipose tissue and liver fat fraction in patients with obesity during a very low-calorie-ketogenic diet compared to a standard low-calorie diet.

Cunha GM, Correa de Mello LL, Hasenstab KA, Spina L, Bussade I, Prata Mesiano JM, Coutinho W, Guzman G, Sajoux I · Clinical radiology · 2020-03-20

Randomized clinical trial

317. The Effects of a Low Calorie Ketogenic Diet on Glycaemic Control Variables in Hyperinsulinemic Overweight/Obese Females.

Michalczyk MM, Klonek G, Maszczyk A, Zajac A · Nutrients · 2020-06-22

Other

318. The modified Atkins diet in children with Prader-Willi syndrome.

Felix G, Kossoff E, Barron B, Krekel C, Testa EG, Scheimann A · Orphanet journal of rare diseases · 2020-06-03

Clinical trial / intervention

319. Aggressive weight-loss program with a ketogenic induction phase for the treatment of chronic plaque psoriasis: A proof-of-concept, single-arm, open-label clinical trial.

Castaldo G, Rastrelli L, Galdo G, Molettieri P, Rotondi Aufiero F, Cereda E · Nutrition (Burbank, Los Angeles County, Calif.) · 2020-02-05

Clinical trial / intervention

320. The Ketogenic Diet: Evidence for Optimism but High-Quality Research Needed.

Ludwig DS · The Journal of nutrition · 2019-09-23

Preclinical / mechanistic

321. Male mice placed on a ketogenic diet from postnatal day (P) 21 through adulthood have reduced growth, are hypoactive, show increased freezing in a conditioned fear paradigm, and have spatial learning deficits.

Miles KN, Skelton MR · Brain research · 2020-01-31

Randomized clinical trial

322. Effects of a Ketogenic Diet on Muscle Fatigue in Healthy, Young, Normal-Weight Women: A Randomized Controlled Feeding Trial.

Sjödin A, Hellström F, Sehlstedt E, Svensson M, Burén J · Nutrients · 2020-03-30

Other

323. Comments on "The ketogenic diet: Pros and cons".

Dafoe W, Gyenes GT · Atherosclerosis · 2020-01-20

Systematic review / meta-analysis

324. Efficacy and safety of very low calorie ketogenic diet (VLCKD) in patients with overweight and obesity: A systematic review and meta-analysis.

Castellana M, Conte E, Cignarelli A, Perrini S, Giustina A, Giovanella L, Giorgino F, Trimboli P · Reviews in endocrine & metabolic disorders · 2019-11-11

Case report / case series

325. Treating binge eating and food addiction symptoms with low-carbohydrate Ketogenic diets: a case series.

Carmen M, Safer DL, Saslow LR, Kalayjian T, Mason AE, Westman EC, Sethi S · Journal of eating disorders · 2020-01-29

Other

326. Ketogenic Diets in Critical Care?

Bistrian BR · JPEN. Journal of parenteral and enteral nutrition · 2019-06-27

Preclinical / mechanistic

327. Ketogenic diet in combination with voluntary exercise impacts markers of hepatic metabolism and oxidative stress in male and female Wistar rats.

Moore MP, Cunningham RP, Kelty TJ, Boccardi LR, Nguyen NY, Booth FW, Rector RS · Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme · 2019-05-22

Clinical trial / intervention

328. Therapeutic action of ketogenic enteral nutrition in obese and overweight patients: a retrospective interventional study.

Papadia C, Bassett P, Cappello G, Forbes A, Lazarescu V, Shidrawi R · Internal and emergency medicine · 2019-05-14

Clinical trial / intervention

329. Effects of Very Low Calorie Ketogenic Diet on the Orexinergic System, Visceral Adipose Tissue, and ROS Production.

Valenzano A, Polito R, Trimigno V, Di Palma A, Moscatelli F, Corso G, Sessa F, Salerno M, Montana A, Di Nunno N, Astuto M, Daniele A, Carotenuto M, Messina G, Cibelli G, Monda V · Antioxidants (Basel, Switzerland) · 2019-12-13

Other

330. Mystery or method? Evaluating claims of increased energy expenditure during a ketogenic diet.

Hall KD · PloS one · 2019-12-09

Other

331. Energy expenditure and body composition changes after an isocaloric ketogenic diet in overweight and obese men: A secondary analysis of energy expenditure and physical activity.

Friedman MI, Appel S · PloS one · 2019-12-09

Other

332. Ketogenic Diets for Diabetes and Obesity-Reply.

Joshi S, Ostfeld RJ, McMacken M · JAMA internal medicine · 2019-12-03

Other

333. Ketogenic Diet for Obesity and Diabetes.

Yancy WS, Mitchell NS, Westman EC · JAMA internal medicine · 2019-12-03

Other

334. Ketogenic Diets for Diabetes and Obesity.

Hecht FM · JAMA internal medicine · 2019-12-03

Clinical trial / intervention

335. Ketogenic Diet: an Endocrinologist Perspective.

Kuchkuntla AR, Shah M, Velapati S, Gershuni VM, Rajjo T, Nanda S, Hurt RT, Mundi MS · Current nutrition reports · 2019-11-11

Preclinical / mechanistic

336. Attenuation of stress-induced weight loss with a ketogenic diet.

Sahagun E, Ward LM, Kinzig KP · Physiology & behavior · 2019-08-17

Clinical trial / intervention

337. Assessment of micronutrients in a 12-wk ketogenic diet in obese adults.

Kenig S, Petelin A, Poklar Vatovec T, Mohorko N, Jenko-Pražnikar Z · Nutrition (Burbank, Los Angeles County, Calif.) · 2019-06-14

Systematic review / meta-analysis

338. Very-low-calorie ketogenic diet (VLCKD) in the management of metabolic diseases: systematic review and consensus statement from the Italian Society of Endocrinology (SIE).

Caprio M, Infante M, Moriconi E, Armani A, Fabbri A, Mantovani G, Mariani S, Lubrano C, Poggiogalle E, Migliaccio S, Donini LM, Basciani S, Cignarelli A, Conte E, Ceccarini G, Bogazzi F, Cimino L, Condorelli RA, La Vignera S, Calogero AE, Gambineri A, Vignozzi L, Prodam F, Aimaretti G, Linsalata G, Buralli S, Monzani F, Aversa A, Vettor R, Santini F, Vitti P, Gnessi L, Pagotto U, Giorgino F, Colao A, Lenzi A, Cardiovascular Endocrinology Club of the Italian Society of Endocrinology · Journal of endocrinological investigation · 2019-05-20

Preclinical / mechanistic

339. Ketogenic diet compromises vertebral microstructure and biomechanical characteristics in mice.

Wu X, Ding J, Xu X, Wang X, Liu J, Jiang J, Liu Q, Kong G, Huang Z, Yang Z, Zhu Q · Journal of bone and mineral metabolism · 2019-04-09

Review

340. The management of very low-calorie ketogenic diet in obesity outpatient clinic: a practical guide.

Muscogiuri G, Barrea L, Laudisio D, Pugliese G, Salzano C, Savastano S, Colao A · Journal of translational medicine · 2019-10-29

Case report / case series

341. Ketogenic Weight Loss Diet Rapidly Unmasks an Insulinoma.

Meier E, Winnicka L, Lau M, Vo D, Joutovsky A, Shenoy MA · Case reports in endocrinology · 2019-10-27

Systematic review / meta-analysis

342. [Weight loss and body composition changes through ketogenic diet and physical activity: a methodological and systematic review].

Martín-Moraleda E, Delisle C, Collado Mateo D, Aznar-Lain S · Nutricion hospitalaria · 2019-09-19

Clinical trial / intervention

343. Effect of a Very-Low-Calorie Ketogenic Diet on Circulating Myokine Levels Compared with the Effect of Bariatric Surgery or a Low-Calorie Diet in Patients with Obesity.

Sajoux I, Lorenzo PM, Gomez-Arbelaez D, Zulet MA, Abete I, Castro AI, Baltar J, Portillo MP, Tinahones FJ, Martinez JA, Crujeiras AB, Casanueva FF · Nutrients · 2019-10-04

Randomized clinical trial

344. Effect of Synbiotic Supplementation in a Very-Low-Calorie Ketogenic Diet on Weight Loss Achievement and Gut Microbiota: A Randomized Controlled Pilot Study.

Gutiérrez-Repiso C, Hernández-García C, García-Almeida JM, Bellido D, Martín-Núñez GM, Sánchez-Alcoholado L, Alcaide-Torres J, Sajoux I, Tinahones FJ, Moreno-Indias I · Molecular nutrition & food research · 2019-08-29

Systematic review / meta-analysis

345. Review of current evidence and clinical recommendations on the effects of low-carbohydrate and very-low-carbohydrate (including ketogenic) diets for the management of body weight and other cardiometabolic risk factors: A scientific statement from the National Lipid Association Nutrition and Lifestyle Task Force.

Kirkpatrick CF, Bolick JP, Kris-Etherton PM, Sikand G, Aspry KE, Soffer DE, Willard KE, Maki KC · Journal of clinical lipidology · 2019-09-13

Preclinical / mechanistic

346. The Impact of the Ketogenic Diet on Glial Cells Morphology. A Quantitative Morphological Analysis.

Gzielo K, Soltys Z, Rajfur Z, Setkowicz ZK · Neuroscience · 2019-06-18

Other

347. Ketogenic Diet-Induced Weight Loss is Associated with an Increase in Vitamin D Levels in Obese Adults.

Perticone M, Maio R, Sciacqua A, Suraci E, Pinto A, Pujia R, Zito R, Gigliotti S, Sesti G, Perticone F · Molecules (Basel, Switzerland) · 2019-07-09

Clinical trial / intervention

348. A ketogenic diet for reducing obesity and maintaining capacity for physical activity: hype or hope?

Murphy EA, Jenkins TJ · Current opinion in clinical nutrition and metabolic care · 2019-06-06

Other

349. Editorial: Ketogenic diets: what is the benefit?

Soeters PB · Current opinion in clinical nutrition and metabolic care · 2019-06-05

Other

350. Pilot study of a ketogenic diet in relapsing-remitting MS.

Brenton JN, Banwell B, Bergqvist AGC, Lehner-Gulotta D, Gampper L, Leytham E, Coleman R, Goldman MD · Neurology(R) neuroimmunology & neuroinflammation · 2019-04-12

Case report / case series

351. Prurigo pigmentosa following ketogenic diet and bariatric surgery: A growing association.

Alshaya MA, Turkmani MG, Alissa AM · JAAD case reports · 2019-06-08

Review

352. [Ketogenic Diet and its Evidence-Based Therapeutic Implementation in Endocrine Diseases].

Stocker RK, Reber Aubry E, Bally L, Nuoffer JM, Stanga Z · Praxis · 2019-06-13

Clinical trial / intervention

353. Lysosomal Acid Lipase as a Molecular Target of the Very Low Carbohydrate Ketogenic Diet in Morbidly Obese Patients: The Potential Effects on Liver Steatosis and Cardiovascular Risk Factors.

Ministrini S, Calzini L, Nulli Migliola E, Ricci MA, Roscini AR, Siepi D, Tozzi G, Daviddi G, Martorelli EE, Paganelli MT, Lupattelli G · Journal of clinical medicine · 2019-05-07

Clinical trial / intervention

354. Low-Carb and Ketogenic Diets in Type 1 and Type 2 Diabetes.

Bolla AM, Caretto A, Laurenzi A, Scavini M, Piemonti L · Nutrients · 2019-04-26

Other

355. Pre ketogenic diet counselling.

Kalra S, Singla R, Rosha R, Sharma S, Surana V, Kalra B · JPMA. The Journal of the Pakistan Medical Association · 2019-04-20

Preclinical / mechanistic

356. The effect of ketogenic diet on behaviors and synaptic functions of naive mice.

Huang J, Li YQ, Wu CH, Zhang YL, Zhao ST, Chen YJ, Deng YH, Xuan A, Sun XD · Brain and behavior · 2019-03-07

Clinical trial / intervention

357. Weight loss, improved physical performance, cognitive function, eating behavior, and metabolic profile in a 12-week ketogenic diet in obese adults.

Mohorko N, Černelič-Bizjak M, Poklar-Vatovec T, Grom G, Kenig S, Petelin A, Jenko-Pražnikar Z · Nutrition research (New York, N.Y.) · 2018-11-12

Other

358. Ketogenic Diet Acts on Body Remodeling and MicroRNAs Expression Profile.

Cannataro R, Perri M, Gallelli L, Caroleo MC, De Sarro G, Cione E · MicroRNA (Shariqah, United Arab Emirates) · 2018-06-29

Randomized clinical trial

359. Pre-operative Very Low Calorie Ketogenic Diet (VLCKD) vs. Very Low Calorie Diet (VLCD): Surgical Impact.

Albanese A, Prevedello L, Markovich M, Busetto L, Vettor R, Foletto M · Obesity surgery · 2018-09-27

Randomized clinical trial

360. Two-Week Exclusive Supplementation of Modified Ketogenic Nutrition Drink Reserves Lean Body Mass and Improves Blood Lipid Profile in Obese Adults: A Randomized Clinical Trial.

Choi HR, Kim J, Lim H, Park YK · Nutrients · 2018-12-03

Other

361. Ketogenic diet for weight loss.

Ting R, Dugré N, Allan GM, Lindblad AJ · Canadian family physician Medecin de famille canadien · 2018-12-14

Clinical trial / intervention

362. Ketogenic diet: situational analysis of current nutrition guidelines.

Kalra S, Singla R, Rosha R, Dhawan M · JPMA. The Journal of the Pakistan Medical Association · 2018-12-04

Other

363. Guiding Ketogenic Diet with Breath Acetone Sensors.

Güntner AT, Kompalla JF, Landis H, Theodore SJ, Geidl B, Sievi NA, Kohler M, Pratsinis SE, Gerber PA · Sensors (Basel, Switzerland) · 2018-10-28

Randomized clinical trial

364. Effect of A Very Low-Calorie Ketogenic Diet on Food and Alcohol Cravings, Physical and Sexual Activity, Sleep Disturbances, and Quality of Life in Obese Patients.

Castro AI, Gomez-Arbelaez D, Crujeiras AB, Granero R, Aguera Z, Jimenez-Murcia S, Sajoux I, Lopez-Jaramillo P, Fernandez-Aranda F, Casanueva FF · Nutrients · 2018-09-21

Review

366. Nutritional Ketosis for Weight Management and Reversal of Metabolic Syndrome.

Gershuni VM, Yan SL, Medici V · Current nutrition reports · 2018-08-22

Case report / case series

367. Successful treatment of obesity and insulin resistance via ketogenic diet status post Roux-en-Y.

Handley RT, Bentley RE, Brown TL, Annan AA · BMJ case reports · 2018-08-17

Randomized clinical trial

368. A Ketogenic Diet Reduces Central Obesity and Serum Insulin in Women with Ovarian or Endometrial Cancer.

Cohen CW, Fontaine KR, Arend RC, Alvarez RD, Leath CA, Huh WK, Bevis KS, Kim KH, Straughn JM, Gower BA · The Journal of nutrition · 2017-11-30

Clinical trial / intervention

369. A ketogenic diet reduces metabolic syndrome-induced allodynia and promotes peripheral nerve growth in mice.

Cooper MA, Menta BW, Perez-Sanchez C, Jack MM, Khan ZW, Ryals JM, Winter M, Wright DE · Experimental neurology · 2018-05-17

Clinical trial / intervention

370. A 4-Week Preoperative Ketogenic Micronutrient-Enriched Diet Is Effective in Reducing Body Weight, Left Hepatic Lobe Volume, and Micronutrient Deficiencies in Patients Undergoing Bariatric Surgery: a Prospective Pilot Study.

Schiavo L, Pilone V, Rossetti G, Barbarisi A, Cesaretti M, Iannelli A · Obesity surgery · 2018-03-05

Randomized clinical trial

371. Efficacy of ketogenic diet on body composition during resistance training in trained men: a randomized controlled trial.

Vargas S, Romance R, Petro JL, Bonilla DA, Galancho I, Espinar S, Kreider RB, Benítez-Porres J · Journal of the International Society of Sports Nutrition · 2018-07-09

Other

372. Metabolic effects, safety, and acceptability of very low-calorie ketogenic dietetic scheme on candidates for bariatric surgery.

Pilone V, Tramontano S, Renzulli M, Romano M, Cobellis L, Berselli T, Schiavo L · Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery · 2018-03-21

Clinical trial / intervention

373. Resting metabolic rate of obese patients under very low calorie ketogenic diet.

Gomez-Arbelaez D, Crujeiras AB, Castro AI, Martinez-Olmos MA, Canton A, Ordoñez-Mayan L, Sajoux I, Galban C, Bellido D, Casanueva FF · Nutrition & metabolism · 2018-02-17

Preclinical / mechanistic

374. The modification of the ketogenic diet mitigates its stunting effects in rodents.

Liśkiewicz AD, Kasprowska-Liśkiewicz D, Sługocka A, Nowacka-Chmielewska MM, Wiaderkiewicz J, Jędrzejowska-Szypułka H, Barski JJ, Lewin-Kowalik J · Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme · 2017-10-18

Other

375. Interest in the Ketogenic Diet Grows for Weight Loss and Type 2 Diabetes.

Abbasi J · JAMA · 2018-01-18

Review

376. Ketogenic diet in endocrine disorders: Current perspectives.

Gupta L, Khandelwal D, Kalra S, Gupta P, Dutta D, Aggarwal S · Journal of postgraduate medicine · 2017-10-13

Clinical trial / intervention

377. Acid-base safety during the course of a very low-calorie-ketogenic diet.

Gomez-Arbelaez D, Crujeiras AB, Castro AI, Goday A, Mas-Lorenzo A, Bellon A, Tejera C, Bellido D, Galban C, Sajoux I, Lopez-Jaramillo P, Casanueva FF · Endocrine · 2017-09-15

Review

378. Dietary guidelines in type 2 diabetes: the Nordic diet or the ketogenic diet?

Magnusdottir OK, Gunnarsdottir I, Birgisdóttir BE · Current opinion in endocrinology, diabetes, and obesity · 2017-07-21

Preclinical / mechanistic

379. The ketogenic diet affects the social behavior of young male rats.

Kasprowska-Liśkiewicz D, Liśkiewicz AD, Nowacka-Chmielewska MM, Nowicka J, Małecki A, Barski JJ · Physiology & behavior · 2017-06-13

Preclinical / mechanistic

380. Beta-adrenergic receptors are critical for weight loss but not for other metabolic adaptations to the consumption of a ketogenic diet in male mice.

Douris N, Desai BN, Fisher FM, Cisu T, Fowler AJ, Zarebidaki E, Nguyen NLT, Morgan DA, Bartness TJ, Rahmouni K, Flier JS, Maratos-Flier E · Molecular metabolism · 2017-06-06

Observational human study

381. Timeline of changes in appetite during weight loss with a ketogenic diet.

Nymo S, Coutinho SR, Jørgensen J, Rehfeld JF, Truby H, Kulseng B, Martins C · International journal of obesity (2005) · 2017-04-25

Review

382. [Ketogenic diets : the miraculous solution ?].

Kosinski C, Jornayvaz FR · Revue medicale suisse · 2017-06-23

Other

383. The Ketogenic Diet: A Solution to Ireland's Obesity Epidemic?

Tepper J, Frere M · Irish medical journal · 2017-03-10

Clinical trial / intervention

384. Body Composition Changes After Very-Low-Calorie Ketogenic Diet in Obesity Evaluated by 3 Standardized Methods.

Gomez-Arbelaez D, Bellido D, Castro AI, Ordoñez-Mayan L, Carreira J, Galban C, Martinez-Olmos MA, Crujeiras AB, Sajoux I, Casanueva FF · The Journal of clinical endocrinology and metabolism · 2016-06-14

Other

385. A very low calorie ketogenic diet improves weight loss and quality of life in patients with adjustable gastric banding.

Taus M, Fumelli D, Busni D, Borroni F, Sebastianelli S, Nicolai G, Nicolai A · Annali italiani di chirurgia · 2017-06-13

Randomized clinical trial

386. Obesity treatment by very low-calorie-ketogenic diet at two years: reduction in visceral fat and on the burden of disease.

Moreno B, Crujeiras AB, Bellido D, Sajoux I, Casanueva FF · Endocrine · 2016-09-13

Randomized clinical trial

387. Effect of DHA supplementation in a very low-calorie ketogenic diet in the treatment of obesity: a randomized clinical trial.

de Luis D, Domingo JC, Izaola O, Casanueva FF, Bellido D, Sajoux I · Endocrine · 2016-04-27

Randomized clinical trial

388. Short-term safety, tolerability and efficacy of a very low-calorie-ketogenic diet interventional weight loss program versus hypocaloric diet in patients with type 2 diabetes mellitus.

Goday A, Bellido D, Sajoux I, Crujeiras AB, Burguera B, García-Luna PP, Oleaga A, Moreno B, Casanueva FF · Nutrition & diabetes · 2016-09-19

Observational human study

389. An observational study of sequential protein-sparing, very low-calorie ketogenic diet (Oloproteic diet) and hypocaloric Mediterranean-like diet for the treatment of obesity.

Castaldo G, Monaco L, Castaldo L, Galdo G, Cereda E · International journal of food sciences and nutrition · 2016-05-18

Other

390. Modified Atkins diet in advanced malignancies - final results of a safety and feasibility trial within the Veterans Affairs Pittsburgh Healthcare System.

Tan-Shalaby JL, Carrick J, Edinger K, Genovese D, Liman AD, Passero VA, Shah RB · Nutrition & metabolism · 2016-08-12

Clinical trial / intervention

391. Energy expenditure and body composition changes after an isocaloric ketogenic diet in overweight and obese men.

Hall KD, Chen KY, Guo J, Lam YY, Leibel RL, Mayer LE, Reitman ML, Rosenbaum M, Smith SR, Walsh BT, Ravussin E · The American journal of clinical nutrition · 2016-07-06

Randomized clinical trial

392. Very-low-calorie ketogenic diet with aminoacid supplement versus very low restricted-calorie diet for preserving muscle mass during weight loss: a pilot double-blind study.

Merra G, Miranda R, Barrucco S, Gualtieri P, Mazza M, Moriconi E, Marchetti M, Chang TF, De Lorenzo A, Di Renzo L · European review for medical and pharmacological sciences · 2016-07-08

Preclinical / mechanistic

393. Ketogenic diet prevents neuronal firing increase within the substantia nigra during pentylenetetrazole-induced seizure in rats.

Viggiano A, Stoddard M, Pisano S, Operto FF, Iovane V, Monda M, Coppola G · Brain research bulletin · 2016-07-02

Clinical trial / intervention

394. Obesity and tumor growth: inflammation, immunity, and the role of a ketogenic diet.

Wright C, Simone NL · Current opinion in clinical nutrition and metabolic care · 2016-05-12

Clinical trial / intervention

395. Very low-calorie ketogenic diet may allow restoring response to systemic therapy in relapsing plaque psoriasis.

Castaldo G, Galdo G, Rotondi Aufiero F, Cereda E · Obesity research & clinical practice · 2015-11-11

Guideline / consensus

396. Impact of a ketogenic diet intervention during radiotherapy on body composition: I. Initial clinical experience with six prospectively studied patients.

Klement RJ, Sweeney RA · BMC research notes · 2016-03-05

Other

397. Low carbohydrate and ketogenic diets in type 2 diabetes.

Clifton P, Carter S, Headland M, Keogh J · Current opinion in lipidology · 2016-01-19

Other

398. Ketogenic diet reverses behavioral abnormalities in an acute NMDA receptor hypofunction model of schizophrenia.

Kraeuter AK, Loxton H, Lima BC, Rudd D, Sarnyai Z · Schizophrenia research · 2015-11-04

Observational human study

399. Middle and Long-Term Impact of a Very Low-Carbohydrate Ketogenic Diet on Cardiometabolic Factors: A Multi-Center, Cross-Sectional, Clinical Study.

Cicero AF, Benelli M, Brancaleoni M, Dainelli G, Merlini D, Negri R · High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2015-05-19

Preclinical / mechanistic

400. Ketogenic diet does not impair spatial ability controlled by the hippocampus in male rats.

Fukushima A, Ogura Y, Furuta M, Kakehashi C, Funabashi T, Akema T · Brain research · 2015-06-23

Review

401. The Ketogenic Diet and Sport: A Possible Marriage?

Paoli A, Bianco A, Grimaldi KA · Exercise and sport sciences reviews · 2015-04-24

Systematic review / meta-analysis

402. Do ketogenic diets really suppress appetite? A systematic review and meta-analysis.

Gibson AA, Seimon RV, Lee CM, Ayre J, Franklin J, Markovic TP, Caterson ID, Sainsbury A · Obesity reviews : an official journal of the International Association for the Study of Obesity · 2014-11-17

Clinical trial / intervention

403. Very low-carbohydrate ketogenic diet before bariatric surgery: prospective evaluation of a sequential diet.

Leonetti F, Campanile FC, Coccia F, Capoccia D, Alessandroni L, Puzziello A, Coluzzi I, Silecchia G · Obesity surgery · 2014-07-10

Randomized clinical trial

404. Comparison of a very low-calorie-ketogenic diet with a standard low-calorie diet in the treatment of obesity.

Moreno B, Bellido D, Sajoux I, Goday A, Saavedra D, Crujeiras AB, Casanueva FF · Endocrine · 2014-03-04

Preclinical / mechanistic

405. Glucose reduces the anticonvulsant effects of the ketogenic diet in EL mice.

Mantis JG, Meidenbauer JJ, Zimick NC, Centeno NA, Seyfried TN · Epilepsy research · 2014-06-02

Other

406. Ketogenic diet in children with intractable epilepsy: what about resting energy expenditure and growth?

Bertoli S, Battezzati A, Tagliabue A · Developmental medicine and child neurology · 2014-05-15

Other

407. Long-term impact of the ketogenic diet on growth and resting energy expenditure in children with intractable epilepsy.

Groleau V, Schall JI, Stallings VA, Bergqvist CA · Developmental medicine and child neurology · 2014-04-20

Case report / case series

408. Long-term effects of a ketogenic diet on body composition and bone mineralization in GLUT-1 deficiency syndrome: a case series.

Bertoli S, Trentani C, Ferraris C, De Giorgis V, Veggiotti P, Tagliabue A · Nutrition (Burbank, Los Angeles County, Calif.) · 2014-01-29

Observational human study

409. Early efficacy of the ketogenic diet is not affected by initial body mass index percentile.

Shull S, Diaz-Medina G, Wong-Kisiel L, Nickels K, Eckert S, Wirrell E · Pediatric neurology · 2014-01-07

Preclinical / mechanistic

410. Long-term ketogenic diet causes glucose intolerance and reduced β- and α-cell mass but no weight loss in mice.

Ellenbroek JH, van Dijck L, Töns HA, Rabelink TJ, Carlotti F, Ballieux BE, de Koning EJ · American journal of physiology. Endocrinology and metabolism · 2014-01-07

Clinical trial / intervention

411. Ketogenic diet for obesity: friend or foe?

Paoli A · International journal of environmental research and public health · 2014-02-19

Preclinical / mechanistic

412. A gestational ketogenic diet alters maternal metabolic status as well as offspring physiological growth and brain structure in the neonatal mouse.

Sussman D, Ellegood J, Henkelman M · BMC pregnancy and childbirth · 2013-10-29

Systematic review / meta-analysis

413. Very-low-carbohydrate ketogenic diet v. low-fat diet for long-term weight loss: a meta-analysis of randomised controlled trials.

Bueno NB, de Melo IS, de Oliveira SL, da Rocha Ataide T · The British journal of nutrition · 2013-05-07

Review

414. Beyond weight loss: a review of the therapeutic uses of very-low-carbohydrate (ketogenic) diets.

Paoli A, Rubini A, Volek JS, Grimaldi KA · European journal of clinical nutrition · 2013-06-26

Preclinical / mechanistic

415. Fgf21 impairs adipocyte insulin sensitivity in mice fed a low-carbohydrate, high-fat ketogenic diet.

Murata Y, Nishio K, Mochiyama T, Konishi M, Shimada M, Ohta H, Itoh N · PloS one · 2013-07-09

Preclinical / mechanistic

416. A ketogenic diet increases brown adipose tissue mitochondrial proteins and UCP1 levels in mice.

Srivastava S, Baxa U, Niu G, Chen X, Veech RL · IUBMB life · 2012-12-10

Preclinical / mechanistic

417. A very low carbohydrate ketogenic diet prevents the progression of hepatic steatosis caused by hyperglycemia in a juvenile obese mouse model.

Okuda T, Morita N · Nutrition & diabetes · 2012-11-12

Clinical trial / intervention

418. Effect of low-calorie versus low-carbohydrate ketogenic diet in type 2 diabetes.

Hussain TA, Mathew TC, Dashti AA, Asfar S, Al-Zaid N, Dashti HM · Nutrition (Burbank, Los Angeles County, Calif.) · 2012-06-05

Preclinical / mechanistic

419. Ketogenic diet protects against epileptogenesis as well as neuronal loss in amygdaloid-kindling seizures.

Jiang Y, Yang Y, Wang S, Ding Y, Guo Y, Zhang MM, Wen SQ, Ding MP · Neuroscience letters · 2011-12-13

Randomized clinical trial

420. Metabolic impact of a ketogenic diet compared to a hypocaloric diet in obese children and adolescents.

Partsalaki I, Karvela A, Spiliotis BE · Journal of pediatric endocrinology & metabolism : JPEM · 2012-11-20

Preclinical / mechanistic

421. Central infusion of ketone bodies modulates body weight and hepatic insulin sensitivity by modifying hypothalamic leptin and insulin signaling pathways in type 2 diabetic rats.

Park S, Kim DS, Daily JW · Brain research · 2011-05-24

Preclinical / mechanistic

422. A ketogenic diet delays weight loss and does not impair working memory or motor function in the R6/2 1J mouse model of Huntington's disease.

Ruskin DN, Ross JL, Kawamura M, Ruiz TL, Geiger JD, Masino SA · Physiology & behavior · 2011-04-09

Guideline / consensus

423. A pilot study of the Spanish Ketogenic Mediterranean Diet: an effective therapy for the metabolic syndrome.

Pérez-Guisado J, Muñoz-Serrano A · Journal of medicinal food · 2011-05-25

Review

424. [The ketogenic diet: an underappreciated therapeutic option?].

Paoli A, Canato M, Toniolo L, Bargossi AM, Neri M, Mediati M, Alesso D, Sanna G, Grimaldi KA, Fazzari AL, Bianco A · La Clinica terapeutica · 2011-11-02

Preclinical / mechanistic

425. Biochemical effect of a ketogenic diet on the brains of obese adult rats.

Mohamed HE, El-Swefy SE, Rashed LA, Abd El-Latif SK · Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia · 2010-04-14

Preclinical / mechanistic

426. Restricted ketogenic diet enhances the therapeutic action of N-butyldeoxynojirimycin towards brain GM2 accumulation in adult Sandhoff disease mice.

Denny CA, Heinecke KA, Kim YP, Baek RC, Loh KS, Butters TD, Bronson RT, Platt FM, Seyfried TN · Journal of neurochemistry · 2010-04-03

Preclinical / mechanistic

427. Ketogenic diet slows down mitochondrial myopathy progression in mice.

Ahola-Erkkilä S, Carroll CJ, Peltola-Mjösund K, Tulkki V, Mattila I, Seppänen-Laakso T, Oresic M, Tyynismaa H, Suomalainen A · Human molecular genetics · 2010-02-17

Preclinical / mechanistic

428. Effects of consuming a high carbohydrate diet after eight weeks of exposure to a ketogenic diet.

Honors MA, Davenport BM, Kinzig KP · Nutrition & metabolism · 2009-11-19

Preclinical / mechanistic

429. A very low carbohydrate ketogenic diet improves glucose tolerance in ob/ob mice independently of weight loss.

Badman MK, Kennedy AR, Adams AC, Pissios P, Maratos-Flier E · American journal of physiology. Endocrinology and metabolism · 2009-09-08

Preclinical / mechanistic

430. Ketogenic diet disrupts the circadian clock and increases hypofibrinolytic risk by inducing expression of plasminogen activator inhibitor-1.

Oishi K, Uchida D, Ohkura N, Doi R, Ishida N, Kadota K, Horie S · Arteriosclerosis, thrombosis, and vascular biology · 2009-07-23

Preclinical / mechanistic

431. Maintenance on a ketogenic diet: voluntary exercise, adiposity and neuroendocrine effects.

Kinzig KP, Taylor RJ · International journal of obesity (2005) · 2009-06-09

Preclinical / mechanistic

432. Improvement in motor and exploratory behavior in Rett syndrome mice with restricted ketogenic and standard diets.

Mantis JG, Fritz CL, Marsh J, Heinrichs SC, Seyfried TN · Epilepsy & behavior : E&B · 2009-02-26

Preclinical / mechanistic

433. Ketogenic diet attenuates kainic acid-induced hippocampal cell death by decreasing AMPK/ACC pathway activity and HSP70.

Jeon BT, Lee DH, Kim KH, Kim HJ, Kang SS, Cho GJ, Choi WS, Roh GS · Neuroscience letters · 2009-01-31

Other

434. [Ketogenic diets: additional benefits to the weight loss and unfounded secondary effects].

Pérez-Guisado J · Archivos latinoamericanos de nutricion · 2009-04-17

Observational human study

435. Spanish Ketogenic Mediterranean Diet: a healthy cardiovascular diet for weight loss.

Pérez-Guisado J, Muñoz-Serrano A, Alonso-Moraga A · Nutrition journal · 2008-10-26

Preclinical / mechanistic

436. Anticonvulsant profile of a balanced ketogenic diet in acute mouse seizure models.

Samala R, Willis S, Borges K · Epilepsy research · 2008-06-18

Case report / case series

437. The modified Atkins diet: a potential treatment for developing countries.

Kossoff EH, Dorward JL, Molinero MR, Holden KR · Epilepsia · 2008-09-11

Guideline / consensus

438. [Ketogenic diets and weight loss: basis and effectiveness].

Pérez-Guisado J · Archivos latinoamericanos de nutricion · 2008-10-07

Preclinical / mechanistic

439. Ketogenic diets cause opposing changes in synaptic morphology in CA1 hippocampus and dentate gyrus of late-adult rats.

Balietti M, Giorgetti B, Fattoretti P, Grossi Y, Di Stefano G, Casoli T, Platano D, Solazzi M, Orlando F, Aicardi G, Bertoni-Freddari C · Rejuvenation research · 2008-07-03

Preclinical / mechanistic

440. A ketogenic diet rescues the murine succinic semialdehyde dehydrogenase deficient phenotype.

Nylen K, Velazquez JL, Likhodii SS, Cortez MA, Shen L, Leshchenko Y, Adeli K, Gibson KM, Burnham WM, Snead OC · Experimental neurology · 2007-11-29

Review

441. Ketogenic diets for weight loss: A review of their principles, safety and efficacy.

Sumithran P, Proietto J · Obesity research & clinical practice · 2007-06-25

Randomized clinical trial

442. Effects of a high-protein ketogenic diet on hunger, appetite, and weight loss in obese men feeding ad libitum.

Johnstone AM, Horgan GW, Murison SD, Bremner DM, Lobley GE · The American journal of clinical nutrition · 2008-01-08

Other

443. Effect of short-term ketogenic diet on redox status of human blood.

Nazarewicz RR, Ziolkowski W, Vaccaro PS, Ghafourifar P · Rejuvenation research · 2007-08-01

Other

444. Ketogenic diet: electrophysiological effects on the normal human cortex.

Cantello R, Varrasi C, Tarletti R, Cecchin M, D'Andrea F, Veggiotti P, Bellomo G, Monaco F · Epilepsia · 2007-06-11

Clinical trial / intervention

445. Beneficial effects of ketogenic diet in obese diabetic subjects.

Dashti HM, Mathew TC, Khadada M, Al-Mousawi M, Talib H, Asfar SK, Behbahani AI, Al-Zaid NS · Molecular and cellular biochemistry · 2007-04-20

Preclinical / mechanistic

446. A high-fat, ketogenic diet induces a unique metabolic state in mice.

Kennedy AR, Pissios P, Otu H, Roberson R, Xue B, Asakura K, Furukawa N, Marino FE, Liu FF, Kahn BB, Libermann TA, Maratos-Flier E · American journal of physiology. Endocrinology and metabolism · 2007-02-13

Case report / case series

447. False-positive breath-alcohol test after a ketogenic diet.

Jones AW, Rössner S · International journal of obesity (2005) · 2006-08-08

Other

448. Benefits of ketogenic diets.

Krilanovich NJ · The American journal of clinical nutrition · 2007-01-09

Preclinical / mechanistic

449. Leptin contributes to slower weight gain in juvenile rodents on a ketogenic diet.

Thio LL, Erbayat-Altay E, Rensing N, Yamada KA · Pediatric research · 2006-08-28

Clinical trial / intervention

450. Long term effects of ketogenic diet in obese subjects with high cholesterol level.

Dashti HM, Al-Zaid NS, Mathew TC, Al-Mousawi M, Talib H, Asfar SK, Behbahani AI · Molecular and cellular biochemistry · 2006-04-21

Randomized clinical trial

451. Ketogenic low-carbohydrate diets have no metabolic advantage over nonketogenic low-carbohydrate diets.

Johnston CS, Tjonn SL, Swan PD, White A, Hutchins H, Sears B · The American journal of clinical nutrition · 2006-05-11

Other

452. The effects of a low-carbohydrate, ketogenic diet on the polycystic ovary syndrome: a pilot study.

Mavropoulos JC, Yancy WS, Hepburn J, Westman EC · Nutrition & metabolism · 2005-12-16

Preclinical / mechanistic

453. A comparison of the ability of a 4:1 ketogenic diet and a 6.3:1 ketogenic diet to elevate seizure thresholds in adult and young rats.

Nylen K, Likhodii S, Abdelmalik PA, Clarke J, Burnham WM · Epilepsia · 2005-08-03

Preclinical / mechanistic

454. The antidepressant properties of the ketogenic diet.

Murphy P, Likhodii S, Nylen K, Burnham WM · Biological psychiatry · 2004-02-27

Preclinical / mechanistic

455. A cDNA microarray analysis of gene expression profiles in rat hippocampus following a ketogenic diet.

Noh HS, Lee HP, Kim DW, Kang SS, Cho GJ, Rho JM, Choi WS · Brain research. Molecular brain research · 2004-06-15

Other

456. Long-term effects of a ketogenic diet in obese patients.

Dashti HM, Mathew TC, Hussein T, Asfar SK, Behbahani A, Khoursheed MA, Al-Sayer HM, Bo-Abbas YY, Al-Zaid NS · Experimental and clinical cardiology · 2009-07-31

Review

457. A review of low-carbohydrate ketogenic diets.

Westman EC, Mavropoulos J, Yancy WS, Volek JS · Current atherosclerosis reports · 2003-10-04

Other

458. Ketogenic diet modifies the risk factors of heart disease in obese patients.

Dashti HM, Bo-Abbas YY, Asfar SK, Mathew TC, Hussein T, Behbahani A, Khoursheed MA, Al-Sayer HM, Al-Zaid NS · Nutrition (Burbank, Los Angeles County, Calif.) · 2003-10-16

Other

459. Metabolic syndrome and low-carbohydrate ketogenic diets in the medical school biochemistry curriculum.

Feinman RD, Makowske M · Metabolic syndrome and related disorders · 2008-03-29

Observational human study

460. The ketogenic diet: adolescents can do it, too.

Mady MA, Kossoff EH, McGregor AL, Wheless JW, Pyzik PL, Freeman JM · Epilepsia · 2003-06-07

Preclinical / mechanistic

461. A ketogenic diet increases brain insulin-like growth factor receptor and glucose transporter gene expression.

Cheng CM, Kelley B, Wang J, Strauss D, Eagles DA, Bondy CA · Endocrinology · 2003-05-15

Preclinical / mechanistic

462. Calorie restriction of a high-carbohydrate diet elevates the threshold of PTZ-induced seizures to values equal to those seen with a ketogenic diet.

Eagles DA, Boyd SJ, Kotak A, Allan F · Epilepsy research · 2003-05-14

Observational human study

463. [Nutritional status and bone mineral mass in children treated with ketogenic diet].

Bertoli S, Striuli L, Testolin G, Cardinali S, Veggiotti P, Salvatori GC, Tagliabue A · Recenti progressi in medicina · 2003-02-01

Observational human study

464. Growth of children on the ketogenic diet.

Vining EP, Pyzik P, McGrogan J, Hladky H, Anand A, Kriegler S, Freeman JM · Developmental medicine and child neurology · 2002-11-29

Observational human study

465. Growth retardation in children with epilepsy on the ketogenic diet: a retrospective chart review.

Williams S, Basualdo-Hammond C, Curtis R, Schuller R · Journal of the American Dietetic Association · 2002-03-21

Other

466. Growth and nutritional outcomes of children treated with the ketogenic diet.

Couch SC, Schwarzman F, Carroll J, Koenigsberger D, Nordli DR, Deckelbaum RJ, DeFelice AR · Journal of the American Dietetic Association · 1999-12-28

Other

467. The effects of a high-protein, low-fat, ketogenic diet on adolescents with morbid obesity: body composition, blood chemistries, and sleep abnormalities.

Willi SM, Oexmann MJ, Wright NM, Collop NA, Key LL · Pediatrics · 1998-01-17

Preclinical / mechanistic

468. Hepatic gluconeogenic and ketogenic interrelationships in the lactating cow.

Aiello RJ, Kenna TM, Herbein JH · Journal of dairy science · 1984-08-01

Other

469. Capacity for moderate exercise in obese subjects after adaptation to a hypocaloric, ketogenic diet.

Phinney SD, Horton ES, Sims EA, Hanson JS, Danforth E, LaGrange BM · The Journal of clinical investigation · 1980-11-01

Other

470. Respiratory quotients lower than 0.70 in ketogenic diets.

Schutz Y, Ravussin E · The American journal of clinical nutrition · 1980-06-01

Preclinical / mechanistic

471. Protective effects of ketogenic diets on signs of hypoglycemia.

Johnson WA, Weiner MW · Diabetes · 1978-11-01

Other

472. Composition of weight lost during short-term weight reduction. Metabolic responses of obese subjects to starvation and low-calorie ketogenic and nonketogenic diets.

Yang MU, Van Itallie TB · The Journal of clinical investigation · 1976-09-01

Preclinical / mechanistic

473. Anticonvulsant properties of the ketogenic diet in mice.

Uhlemann ER, Neims AH · The Journal of pharmacology and experimental therapeutics · 1972-02-01

Other

474. Sporadic hypoglycemia: abnormal epinephrine response to the ketogenic diet or to insulin.

Koffler H, Schubert WK, Hug G · The Journal of pediatrics · 1971-03-01

Preclinical / mechanistic

475. Metabolic adaptations and dietary preferences in mice exposed to ketogenic and high-fat high-sucrose diets.

Penna-de-Carvalho A, Nagagata BA, Guarnieri RS, Borges MMS, Teixeira LPM, Ferreira-Machado SC, Aguila MB · Nutrition (Burbank, Los Angeles County, Calif.) · 2025-11-23

Randomized clinical trial

476. Taxonomic and functional shifts in the microbiome of severely obese, prediabetic patients: Ketogenic diet versus energy-matched standard diet.

Stone J, Tripyla A, Scalise MC, Balmer ML, Bally L, Meinel DM · Diabetes, obesity & metabolism · 2025-12-15

Clinical trial / intervention

477. The Ketogenic Diet in Obesity Management: Friend or Foe?

Alum EU, Izah SC, Betiang PA, Paul-Chima Ugwu O, Ainebyoona C, Uti DE, Echegu DA, Alum BN · Cell biochemistry and biophysics · 2025-08-29

Observational human study

478. Very low-calorie ketogenic diet reduces left ventricular mass and epicardial adipose tissue in post-menopausal women with essential hypertension and obesity: A single-center, prospective, open-label, clinical study.

Pala B, Nardoianni G, Pennazzi L, di Renzo L, Gualtieri P, Frank G, Baldi T, Barbato E, Tocci G · Nutrition, metabolism, and cardiovascular diseases : NMCD · 2025-09-13

Observational human study

479. Very low energy ketogenic therapy: an anti-inflammatory medical nutritional approach for MASLD in obesity.

Barrea L, Verde L, Galasso M, Savastano S, Colao A, Muscogiuri G · Journal of translational medicine · 2025-12-17

Randomized clinical trial

480. Effect of Exogenous Ketones as an Adjunct to Low-Calorie Diet on Metabolic Markers.

Roeth EJ, Parker G, Cooper-Leavitt EF, Beus CG, Braithwaite CR, Morris MD, Reynolds AP, Evans EP, Radford JH, Davis FD, Reynolds PR, Parrish RR, Bikman BT · Nutrients · 2025-11-16

Clinical trial / intervention

481. Therapeutic effectiveness of low-calorie ketogenic diet on body composition and biochemical parameters in polycystic ovary syndrome - An ıntervention study.

Seven Avuk H, Baş M · Nutricion hospitalaria · 2025-11-13

Preclinical / mechanistic

482. Ketamine Sustains and Enhances the Protective Effects of a Ketogenic Diet Against Relapses in an Anorexia Mouse Model.

Dong Y, Wang J, Ge O, Lin Y, Aoki C · Hippocampus · 2025-09-14

Clinical trial / intervention

483. Ketogenic diet in the management of disease.

Luong T, Svart M, Gormsen LC, Søndergaard E · Current opinion in clinical nutrition and metabolic care · 2025-08-07

Randomized clinical trial

484. Digitally enhanced ketogenic diet versus low-fat diet for cardio-renal-metabolic health in a predominantly Hispanic adult population with overweight or obesity: Pilot randomised clinical trial.

Du Y, Wang J, Li S, Meireles C, Saliba A, Castillo A, Goros M, Gelfond J, Choi BY, Qi L, Li C, Sharma K · Diabetes, obesity & metabolism · 2025-08-06

Preclinical / mechanistic

485. Sex Differences in Ketogenic Diet Response Reveal Gonadal Hormone Interaction With FGF21 in Mice.

Zhang Y, Cochran JD, Souvenir RA, Tai W, Xia R, Gladwin BS, Barton NB, Pereira RO, Abel ED · Journal of the Endocrine Society · 2025-08-18

Randomized clinical trial

486. Very low-calorie ketogenic diet and liraglutide as a synergistic strategy for the treatment of obesity: A short-term, non-randomised, observational, real-world clinical evaluation.

Camajani E, Masi D, Spizzichini ML, Cori C, Rossetti R, Spoltore ME, Tuccinardi D, Lubrano C, Gnessi L, Isidori AM, Gianfrilli D, Moretti C, Caprio M, Watanabe M · Diabetes, obesity & metabolism · 2025-07-30

Preclinical / mechanistic

487. Prospective Observational Case Series in Infertile Women with Overweight or Obesity Treated with a Very-Low Calorie Ketogenic Diet (VLCKD) Prior to an In Vitro Fertilization (IVF) Treatment.

Casalechi M, Piontini A, Nicolosi A, Bergomas F, Napolitano F, Turolo S, Reschini M, Riccaboni A, Bellinghieri R, Somigliana E, Vigna L · Nutrients · 2025-09-11

Clinical trial / intervention

488. Effectiveness of Medical Nutrition Therapy in the Management of Patients with Obesity and Endometriosis: from the Mediterranean Diet To the Ketogenic Diet, Through Supplementation. The Role of the Nutritionist in Clinical Management.

Barrea L, Verde L, Annunziata G, Chedraui P, Petraglia F, Cucalón G, Camajani E, Caprio M, Gorini S, Iorio GG, Di Girolamo R, Carbone L, Chapela S, Frias-Toral E, Muscogiuri G · Current obesity reports · 2025-09-08

Randomized clinical trial

489. Effect of a Ketogenic Diet, Time-Restricted Eating or Alternate-Day Fasting on changes in ambulatory blood pressure. A sub-analysis of a randomized clinical trial.

Gómez-Pérez AM, Bandera-Merchán B, Martínez-Montoro JI, Gutiérrez-Bedmar M, Díaz-Perdigones C, Subiri-Verdugo A, Moreno-Indias I, Tinahones FJ · European journal of preventive cardiology · 2025-09-05

Randomized clinical trial

490. Beyond epilepsy management: A narrative review of the health effects of ketogenic diets.

Chamma L, Chamma N, Mattar L, Slaybe M, Haidar S, Rizk R · Nutrition (Burbank, Los Angeles County, Calif.) · 2025-04-16

Observational human study

491. Beyond GLP-1 Agonists: An Adaptive Ketogenic-Mediterranean Protocol to Counter Metabolic Adaptation in Obesity Management.

García-Gorrita C, San Onofre N, Merino-Torres JF, Soriano JM · Nutrients · 2025-08-20

Preclinical / mechanistic

492. Eating a high fat/high carbohydrate diet enhances morphine tolerance, while eating a ketogenic diet mitigates morphine withdrawal in male rats.

Beltran NM, Sullivan LL, Naime GM, Minervini V, Serafine KM · European journal of pharmacology · 2025-05-08

Randomized clinical trial

493. The Effect of Short-Term Healthy Ketogenic Diet Ready-To-Eat Meals Versus Healthy Ketogenic Diet Counselling on Weight Loss in Overweight Adults: A Pilot Randomized Controlled Trial.

Tay MHJ, Yap QV, Lim SL, Ong YWY, Wee VCHT, Khoo CM · Nutrients · 2025-08-01

Observational human study

494. Impact of modified Atkins diet on growth in infants and children with epilepsy.

Chang J, Schimpf S, Phitsanuwong C · Epileptic disorders : international epilepsy journal with videotape · 2025-02-19

Preclinical / mechanistic

495. Chronic stress inhibits weight gain and decreases beta-hydroxybutyrate levels and glucose tolerance in female BALB/c fed a high-fat ketogenic diet.

Cantú-Ruiz AL, Caballero-Hernández D, Gutierrez-Leal I, Martínez-Torres AC, Gomez-Flores R, Tamez-Guerra P, Tamez-Guerra R, Rodríguez-Padilla C · BMC nutrition · 2025-07-25

Case report / case series

496. Ketogenic diet as rescue therapy to access transplantation in obese and advanced stage IV-CKD patients: a case report and literature review.

Caissutti S, Vischini G, Petroni ML, Collini S, Chiocchini ALC, La Manna G · Journal of nephrology · 2025-07-04

Clinical trial / intervention

497. Phenotype-Driven Variability in Longitudinal Body Composition Changes After a Very Low-Calorie Ketogenic Intervention: A Machine Learning Cluster Approach.

de la O V, de Cuevillas B, Henkrich M, Vizmanos B, Nuñez-Garcia M, Sajoux I, de Luis D, Martínez JA · Journal of personalized medicine · 2025-06-14

Review

498. Sex differences in ketogenic diet: are men more likely than women to lose weight?

Jiao Y, Chen X, Liu L, Lu Y, Gao M, Wang Q, Chi X, Mo Y · Frontiers in nutrition · 2025-06-04

Review

499. Therapeutic Applications of Ketogenic Diets in Lipedema: A Narrative Review of Current Evidence.

Sanlier N, Baltacı S · Current obesity reports · 2025-05-26

Preclinical / mechanistic

500. Ketogenic diet prevents obesity-associated pancreatic cancer independent of weight loss and induces pancreatic metabolic reprogramming.

Vélez-Bonet E, Gumpper-Fedus K, Chasser K, Hurst Z, Hsueh HY, Pita-Grisanti V, Liette A, Vulic G, Choueiry F, Zhang H, Zhu J, Knoblaugh SE, Culp S, Volek JS, Cruz-Monserrate Z · bioRxiv : the preprint server for biology · 2025-05-24

Clinical trial / intervention

501. Low-Calorie, High-Protein Ketogenic Diet Versus Low-Calorie, Low-Sodium, and High-Potassium Mediterranean Diet in Overweight Patients and Patients with Obesity with High-Normal Blood Pressure or Grade I Hypertension: The Keto-Salt Pilot Study.

Landolfo M, Stella L, Gezzi A, Spannella F, Turri P, Sabbatini L, Cecchi S, Lucchetti B, Petrelli M, Sarzani R · Nutrients · 2025-05-20

Preclinical / mechanistic

502. Nutritional ketosis modulates the methylation of cancer-related genes in patients with obesity and in breast cancer cells.

Lorenzo PM, Izquierdo AG, Rodriguez-Carnero G, Costa-Fraga N, Díaz-Lagares A, Porca C, de Luis D, Tejera C, De Paz L, Cueva J, Bellido D, Crujeiras AB · Journal of physiology and biochemistry · 2025-03-27

Clinical trial / intervention

503. Illnesses associated with ketosis including diabetic ketoacidosis during very low carbohydrate and ketogenic diets.

Roberts CGP, Athinarayanan SJ, Ratner RE, Umpierrez GE · Diabetes, obesity & metabolism · 2025-02-25

Randomized clinical trial

504. Lesson learned from bariatric surgery: Preventing intra- and perioperative complications in patients with obesity undergoing laparoscopic adrenalectomy: Role of ketogenic preoperative diet: A propensity score matching analysis of a single-center experience.

Musella M, Velotti N, Schiavone V, Franzese A, D'Amato G, Bartolini C, Avella P · Surgery · 2025-01-30

Systematic review / meta-analysis

505. Database Analysis of Application Areas and Global Trends in Ketogenic Diets from 2019 to 2024.

Assmann M, Albrecht I, Frenser M, Marquardt T, Fischer T · Nutrients · 2025-04-27

Clinical trial / intervention

506. Anthropometric Trajectories and Dietary Compliance During a Personalized Ketogenic Program.

García-Gorrita C, Soriano JM, Merino-Torres JF, San Onofre N · Nutrients · 2025-04-27

Case report / case series

507. Remission of OCD and ulcerative colitis with a ketogenic diet: Case Report.

Calabrese L · Frontiers in psychiatry · 2025-04-03

Clinical trial / intervention

508. Advancing Obesity Management: the Very Low-Energy Ketogenic therapy (VLEKT) as an Evolution of the "Traditional" Ketogenic Diet.

Balestra F, Luca M, Panzetta G, Palieri R, Shahini E, Giannelli G, Pergola G, Scavo MP · Current obesity reports · 2025-04-03

Preclinical / mechanistic

509. Obesity-related osteopontin protein and methylation blood levels are differentially modulated by a very low-calorie ketogenic diet or bariatric surgery.

Lorenzo PM, Izquierdo AG, Sajoux I, Nuñez-Garcia M, Gomez-Arbelaez D, Zulet MA, Abete I, Baltar J, de Luis D, Tinahones FJ, Martinez JA, Casanueva FF, Crujeiras AB · Clinical nutrition (Edinburgh, Scotland) · 2025-02-11

Clinical trial / intervention

510. Epigenetic Aging Acceleration in Obesity Is Slowed Down by Nutritional Ketosis Following Very Low-Calorie Ketogenic Diet (VLCKD): A New Perspective to Reverse Biological Age.

Izquierdo AG, Lorenzo PM, Costa-Fraga N, Primo-Martin D, Rodriguez-Carnero G, Nicoletti CF, Martínez JA, Casanueva FF, de Luis D, Diaz-Lagares A, Crujeiras AB · Nutrients · 2025-03-18

Clinical trial / intervention

511. Ketogenic Diets for Body Weight Loss: A Comparison with Other Diets.

Dyńka D, Rodzeń Ł, Rodzeń M, Pacholak-Klimas A, Ede G, Sethi S, Łojko D, Bartoń K, Berry K, Deptuła A, Grzywacz Ż, Martin P, Unwin J, Unwin D · Nutrients · 2025-03-10

Clinical trial / intervention

512. Mitigating muscle loss during weight loss: can nutritional ketosis make a difference? A call for more research.

Athinarayanan SJ, Volek JS · Obesity (Silver Spring, Md.) · 2025-02-13

Systematic review / meta-analysis

513. Effects of ketogenic and low-carbohydrate diets on the body composition of adults with overweight or obesity: A systematic review and meta-analysis of randomised controlled trials.

Leung LY, Tam HL, Ho JK · Clinical nutrition (Edinburgh, Scotland) · 2025-01-18

Case report / case series

514. A Case Series on Combining Modified Mediterranean Diet and Ketogenic Diet in a "Sandwich" Approach for Patients with Lipedema and Comorbidities.

Fedre B, Dessalvi S, Boccardo F · Lymphology · 2025-12-17

Systematic review / meta-analysis

515. Impact of Ketogenic Diet on Weight, Metabolic, and Endocrine Parameters in Women with Polycystic Ovary Syndrome: A Systematic Review and Meta-Analysis.

Turetta C, Turetta C, Giannini A, Tarsitano MG, Gianfrilli D, Paoli A, Kontopantelis E, De Angelis E, Minnetti M, Poggiogalle E, Colizza A, De Vincentiis M, Laganà AS, Bogani G, Palaia I, Muzii L, Di Donato V · Gynecologic and obstetric investigation · 2025-02-20

Case report / case series

516. Changes in body composition during weight reduction in obesity. Balance studies comparing effects of fasting and a ketogenic diet.

Benoit FL, Martin RL, Watten RH · Annals of internal medicine · 1965-10-01

Randomized clinical trial

517. [Effect of ketogenic diet on body weight, intermediary and electrolyte metabolism of obese subjects].

Chmidt H, Janik I, Voigt KD · Deutsche medizinische Wochenschrift (1946) · 1969-01-01

Other

518. [Effects of a ketogenic diet on the glyco-lipidic metabolism in obese subjects of pre-puberal age].

Del Guercio MJ, Carnelutti M, Cantone A · La Pediatria · 1967-03-01

Review

519. Weight reduction: fasting versus a ketogenic diet.

Nutrition reviews · 1966-05-01

GLP-1RA + Ketogenic Metabolism13 studies/publications combining GLP-1-based therapies with ketogenic interventions, ketosis or ketones

Automatically curated from PubMed records in the Metabolic & Endocrine section. Inclusion requires both a GLP-1/incretin therapy concept and a ketogenic, ketosis or ketone-related concept.

Matched peer-reviewed literature
Observational human study

58. Real-world experience with GLP-1 receptor agonists in adults with epilepsy following a modified atkins diet.

El Zibaoui R, McDonald TJW, Henry-Barron BJ, Vizthum D, Cervenka MC · Epilepsy research · 2026-08-14

Observational human study

75. Personalized Combination of a Ketogenic Diet and Low-Dose Semaglutide for Cardiometabolic Health: A Retrospective Case Series.

Parker G, Morris MD, Heggie JR, Cooper-Leavitt EF, Clark CJ, Reynolds AP, Smith HA, Wendel CP, Jensen WJ, Morris TJ, Reynolds PR, Bikman BT · Journal of personalized medicine · 2026-06-12

Randomized clinical trial

98. Very low energy ketogenic diet vs. Mediterranean diet for MASLD: Superior steatosis reduction in a randomised pilot study.

Farrell AM, Paris T, Parr EB, George ES, Howell J, Croagh C, Sutherland T, Page M, McKelvie P, Thompson AJ, Ryan M · JHEP reports : innovation in hepatology · 2026-02-19

Observational human study

381. Timeline of changes in appetite during weight loss with a ketogenic diet.

Nymo S, Coutinho SR, Jørgensen J, Rehfeld JF, Truby H, Kulseng B, Martins C · International journal of obesity (2005) · 2017-04-25

Randomized clinical trial

486. Very low-calorie ketogenic diet and liraglutide as a synergistic strategy for the treatment of obesity: A short-term, non-randomised, observational, real-world clinical evaluation.

Camajani E, Masi D, Spizzichini ML, Cori C, Rossetti R, Spoltore ME, Tuccinardi D, Lubrano C, Gnessi L, Isidori AM, Gianfrilli D, Moretti C, Caprio M, Watanabe M · Diabetes, obesity & metabolism · 2025-07-30

Observational human study

491. Beyond GLP-1 Agonists: An Adaptive Ketogenic-Mediterranean Protocol to Counter Metabolic Adaptation in Obesity Management.

García-Gorrita C, San Onofre N, Merino-Torres JF, Soriano JM · Nutrients · 2025-08-20

Clinical trial / intervention

512. Mitigating muscle loss during weight loss: can nutritional ketosis make a difference? A call for more research.

Athinarayanan SJ, Volek JS · Obesity (Silver Spring, Md.) · 2025-02-13

Clinical trial / intervention

87. The ketogenic diet is not for everyone: contraindications, side effects, and drug interactions.

Dyńka D, Rodzeń Ł, Rodzeń M, Łojko D, Karakuła-Juchnowicz H, Ede G, Grzywacz Ż, Antosik K, Sethi S, Unwin D · Annals of medicine · 2026-01-04

Randomized clinical trial

97. Randomized Crossover Trial of 2-Week Ketone Ester Treatment in Patients With Type 2 Diabetes and Heart Failure With Preserved Ejection Fraction.

Gopalasingam N, Berg-Hansen K, Christensen KH, Ladefoged BT, Poulsen SH, Andersen MJ, Borlaug BA, Nielsen R, Møller N, Wiggers H · Circulation · 2024-08-20

Randomized clinical trial

220. Abdominal fat distribution modulates the metabolic effects of exogenous ketones in individuals with new-onset prediabetes after acute pancreatitis: Results from a randomized placebo-controlled trial.

Bharmal SH, Alarcon Ramos GC, Ko J, Petrov MS · Clinical nutrition ESPEN · 2021-03-21

Randomized clinical trial

479. Effect of ketogenic diet plus dulaglutide on glucose and lipid metabolism in diabetes mellitus.

Gao R, Yan L, Du X, He S, Xue L, Li T, Wei M, Gu Y · Pakistan journal of pharmaceutical sciences · 2025-11-16

Randomized clinical trial

70. Beyond Weight Loss: Comparative Effects of Tirzepatide Plus Low-Energy Ketogenic Versus Low-Calorie Diet on Hepatic Steatosis and Stiffness in MASLD.

Schiavo L, Santella B, Mingo M, Rossetti G, Orio M, Pilone V · Nutrients · 2025-07-24

Opinion

Preserving Lean Mass During GLP-1RA-Induced Weight Loss: The Potential Role of Ketogenic Metabolic Therapy in Improving Weight-Loss Quality

Marco Medeot. Biomed adv. 2026;3(3):89-91.

Diabetes & Glucose Metabolism Recent peer-reviewed literature

Source-audited references from the connected PDF archive. Only papers directly relevant to this topic and ketogenic therapy/ketosis are shown.

1. The Ketogenic Diet in Type 2 Diabetes and Obesity: A Narrative Review of Clinical Evidence

Bibliographic record reviewed for inclusion in the curated Scientific Library.

2. The Impact of Ketogenic Capacity on Lipid Profile in Individuals with Prediabetes or Newly Diagnosed Type 2 Diabetes

Bibliographic record reviewed for inclusion in the curated Scientific Library.

3. Sustained metabolic improvements in a remotely delivered ketogenic nutrition intervention in type 2 diabetes

Bibliographic record reviewed for inclusion in the curated Scientific Library.

4. Impact of very low carbohydrate ketogenic diets on cardiovascular risk factors among patients with type 2 diabetes: systematic review and meta-analysis

Bibliographic record reviewed for inclusion in the curated Scientific Library.

5. Effects of very low-carbohydrate ketogenic diet on lipid metabolism in patients with type 2 diabetes

Bibliographic record reviewed for inclusion in the curated Scientific Library.

6. Low-Carbohydrate and Ketogenic Dietary Patterns for Type 2 Diabetes Management

Bibliographic record reviewed for inclusion in the curated Scientific Library.

7. Ketogenic diet preserves muscle mass and strength in a mouse model of type 2 diabetes

Bibliographic record reviewed for inclusion in the curated Scientific Library.

8. BDH1-mediated β-hydroxybutyrate metabolism ameliorates diabetic kidney disease

Bibliographic record reviewed for inclusion in the curated Scientific Library.

9. Managing type 1 diabetes mellitus with a ketogenic diet

Bibliographic record reviewed for inclusion in the curated Scientific Library.

10. The Effects of Ketogenic Diet on Insulin Sensitivity and Weight Loss

Bibliographic record reviewed for inclusion in the curated Scientific Library.

11. The Role of a Ketogenic Diet in the Treatment of Dementia in Type 2 Diabetes Mellitus

Bibliographic record reviewed for inclusion in the curated Scientific Library.

12. A ketogenic diet improves vascular hyperpermeability in type 2 diabetic mice

Bibliographic record reviewed for inclusion in the curated Scientific Library.

13. Impaired ketogenesis is associated with metabolic-associated fatty liver disease in subjects with type 2 diabetes

Bibliographic record reviewed for inclusion in the curated Scientific Library.

14. Low carbohydrate ketogenic diets reduce cardiovascular risk factor levels in obese or overweight patients with T2DM

Bibliographic record reviewed for inclusion in the curated Scientific Library.

15. Ketogenic Diet Benefits to Weight Loss, Glycemic Control, and Lipid Profiles in Overweight Patients with Type 2 Diabetes Mellitus: A Meta-Analysis of Randomized Controlled Trials

Bibliographic record reviewed for inclusion in the curated Scientific Library.

16. The effect of periodic ketogenic diet on newly diagnosed overweight or obese patients with type 2 diabetes

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Human / clinical or translational evidence

17. Effect of Low-Carbohydrate Diets on Glycemic Control

Original publication title: Effect of Low-Carbohydrate Diets on Glycemic Control

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Human / clinical or translational evidence

18. Greater Reduction in the Proinsulin-C-Peptide Ratio with a Ketogenic Nutritional Intervention

Original publication title: Greater Reduction in the Proinsulin-C-Peptide Ratio with a Ketogenic Nutritional Intervention

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Human / clinical or translational evidence

19. Sustained Metabolic Improvements in a Remotely Delivered Ketogenic Nutrition Intervention

Original publication title: Sustained Metabolic Improvements in a Remotely Delivered Ketogenic Nutrition Intervention

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Systematic review & meta-analysis

20. Impact of Very Low Carbohydrate Ketogenic Diets on Cardiovascular Risk Factors among Patients with Type 2 Diabetes: GRADE-Assessed Systematic Review and Meta-Analysis

Original publication title: Impact of Very Low Carbohydrate Ketogenic Diets on Cardiovascular Risk Factors among Patients with Type 2 Diabetes: GRADE-Assessed Systematic Review and Meta-Analysis

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Human / clinical or translational evidence

21. The Ketogenic Effect of SGLT-2 Inhibitors: Beneficial or Harmful?

Original publication title: The Ketogenic Effect of SGLT-2 Inhibitors: Beneficial or Harmful?

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Systematic review & meta-analysis

22. Effect of Dietary Approaches on Glycemic Control in Patients with Type 2 Diabetes: A Systematic Review with Network Meta-Analysis of Randomized Trials

Original publication title: Effect of Dietary Approaches on Glycemic Control in Patients with Type 2 Diabetes: A Systematic Review with Network Meta-Analysis of Randomized Trials

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Human / clinical or translational evidence

23. Low-Carbohydrate Ketogenic Diets Reduce Cardiovascular Risk Factor Levels in Patients with Type 2 Diabetes

Original publication title: Low-Carbohydrate Ketogenic Diets Reduce Cardiovascular Risk Factor Levels in Patients with Type 2 Diabetes

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Human / clinical or translational evidence

24. Clinical Assessment of Intermittent Fasting with Ketogenic Diet in Glycemic Control and Weight Reduction in Type 2 Diabetes

Original publication title: Clinical Assessment of Intermittent Fasting with Ketogenic Diet in Glycemic Control and Weight Reduction in Type 2 Diabetes

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Review

25. Very Low Carbohydrate Ketogenic Diets in Type 2 Diabetes: Review

Original publication title: Very Low Carbohydrate Ketogenic Diets in Type 2 Diabetes: Review

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Systematic review & meta-analysis

26. Ketogenic Diet Benefits to Weight Loss, Glycemic Control, and Lipid Profiles in Overweight Patients with Type 2 Diabetes: Meta-Analysis of Randomized Controlled Trials

Original publication title: Ketogenic Diet Benefits to Weight Loss, Glycemic Control, and Lipid Profiles in Overweight Patients with Type 2 Diabetes: Meta-Analysis of Randomized Controlled Trials

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Human / clinical or translational evidence

27. 3-Hydroxybutyrate Ameliorates the Progression of Diabetic Nephropathy

Original publication title: 3-Hydroxybutyrate Ameliorates the Progression of Diabetic Nephropathy

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Human / clinical or translational evidence

28. Efficacy of Low Carbohydrate Ketogenic Diet in the Treatment of Type 2 Diabetes

Original publication title: Efficacy of Low Carbohydrate Ketogenic Diet in the Treatment of Type 2 Diabetes

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Systematic review

29. Efficacy of Ketogenic Diets on Type 2 Diabetes: A Systematic Review

Original publication title: Efficacy of Ketogenic Diets on Type 2 Diabetes: A Systematic Review

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Human / clinical or translational evidence

30. Adherence to Low-Carbohydrate Diets in Patients with Type 2 Diabetes

Original publication title: Adherence to Low-Carbohydrate Diets in Patients with Type 2 Diabetes

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Human / clinical or translational evidence

31. Adapting Medication for Type 2 Diabetes to a Low-Carbohydrate Ketogenic Diet

Original publication title: Adapting Medication for Type 2 Diabetes to a Low-Carbohydrate Ketogenic Diet

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Metabolomic review

32. The Ketogenic Diet Through a Metabolomic Lens

Original publication title: The Ketogenic Diet Through a Metabolomic Lens

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Clinical trial / intervention

33. The Ketogenic Diet as Adjunctive Strategy in Cancer Treatment-Therapeutic Benefits and Metabolic Risk Using Breast Cancer as an Example.

Szołtysek J, Szymańska B, Piwowar A · Nutrients · 2026-09-06

Randomized clinical trial

34. Ketogenic diet combined with probiotics for polyendocrine metabolic ovarian syndrome: research progress from the perspective of the gut microbiota-host metabolic axis.

Yang Y, Dai F, He X, Zhao P, Chen Q · Frontiers in nutrition · 2026-09-02

Observational human study

35. Glucose Transporter Type 1 Deficiency Syndrome: Clinical Variability and Challenges in Ketogenic Diet Management in a Paediatric Case Series.

Viegas M, Baptista N, Martins F, Almeida J, Pereira C, Rodrigues F, Salgado J, Ribeiro J, Ferreira S, Diogo R · Journal of clinical medicine · 2026-08-19

Randomized clinical trial

36. Five-year patient-reported outcomes of individualized nutrition therapy supporting nutritional ketosis in adults with type 2 diabetes.

Adams RN, Athinarayanan SJ, Phinney SD, Volek JS, McKenzie AL · Frontiers in nutrition · 2026-08-14

Clinical trial / intervention

37. Ketogenic Diet as an Adjuvant in Epithelial Cancers: Mechanisms, Model Systems, and Translational Opportunities.

Ylikomi T, Nees M · Cancers · 2026-08-12

Case report / case series

38. Early-Onset Euglycemic Diabetic Ketoacidosis Following Empagliflozin Initiation Triggered by Acute Influenza and a Ketogenic Diet.

Meyer MS, Ramesh S, Rammouni Y, Lasry S, Sawan H, Zakaria K · Cureus · 2026-08-09

Other

39. [Ketogenic diet reintroduction in an adult patient with glucose transporter type 1 deficiency syndrome].

Kusakabe S, Osakada Y, Morihara R, Dohi Y, Shimono K, Ishiura H · Rinsho shinkeigaku = Clinical neurology · 2026-08-07

Randomized clinical trial

40. Metabolic Therapy in Glioblastoma-Mapping the Evidence for Ketogenic Diet as an Adjunctive Strategy.

Wiśniewska D, Winiarska M, Krupa-Nurcek S · Nutrients · 2026-08-03

Other

41. Metabolomic Profiling of Plasma in Children with Drug-Resistant Epilepsy: The Effect of the Ketogenic Diet on Energy and Amino Acid Pathways.

Cieślak M, Gątarek P, Safiński P, Przyslo L, Kałużna-Czaplińska J · Nutrients · 2026-07-17

Clinical trial / intervention

42. Hypomanic symptoms and first manic episode during ketogenic diet treatment in a patient taking venlafaxine: a case report with longitudinal glucose-ketone index and clinical monitoring.

Pou-Álvarez M, Casanovas F, Córcoles D, León-Caballero J, Sabaté A, González-Fresnedo AM, Samos P, Perez-Sola V, Martín LM · Frontiers in nutrition · 2026-07-16

Clinical trial / intervention

43. Predicting the efficacy of classic ketogenic diet therapy in children with refractory epilepsy using dynamic changes in the glucose-ketone index (GKI).

Li J, Wang T, Yu L, Ni Y, Li Y, Zhang Y, Zhou S, Wang Y · Seizure · 2026-07-12

Systematic review / meta-analysis

44. Ketogenic diets and cardiovascular health balancing metabolic benefits against lipid-related risk.

Liu H, Wu W, He N, Wang X, Pan S, Zhu L, Ma S, Zhang Y, Liu Z · BMC cardiovascular disorders · 2026-07-07

Randomized clinical trial

45. Very-Low-Energy Ketogenic Therapy Modulates the Metabolic-Antioxidant Axis in Patients with Obesity and Type 2 Diabetes: A Non-Randomized Clinical Trial.

Tini S, Celano S, Pigni S, De Palma E, Ozdemir HI, Raiteri T, Antonioli A, Baima J, Antoniotti V, Caputo M, Marzullo P, Prodam F · Antioxidants (Basel, Switzerland) · 2026-07-04

Systematic review / meta-analysis

46. Ketogenic Diet in the Treatment of Malignant Gliomas: A Systematic Review.

Persiani M, Dallolio L, Masini A, Longobucco Y, Bertoli S, Guberti E, Pellizzari M, Petroni ML, Valeriani F, Gallè F, Sacchetti R · Nutrients · 2026-07-03

Systematic review / meta-analysis

47. The impact of the ketogenic diet on the health of patients with metabolic syndrome: a scoping review.

Winiarska M, Wiśniewska D, Klimas M, Jucha D, Szczupak M, Kobak J, Krupa-Nurcek S · Frontiers in nutrition · 2026-06-29

Preclinical / mechanistic

48. Influence of Ketogenic Diet Lipid Composition on Anxiety-Like Behavior and Neurometabolic Profile in Healthy Rats.

Gurgel GG, de Souza JG, Braga RAM, Rodrigues FM, Faccioli AM, Fortes MEG, da Silva EA, Freitas RAMS, Arida RM, Scorza CA, Bernardes ES, Dos Santos SN, Damasceno NRT · Molecular neurobiology · 2026-06-25

Review

49. Ketogenic Diet in Obesity and Diabetes: A Narrative Review.

An Y, Norris N, Li D, Gunton JE · Nutrients · 2026-06-20

Systematic review / meta-analysis

50. Ketogenic diet therapy in pyruvate dehydrogenase deficiency: Global clinical practice from literature and survey data.

Madsen S, Allender B, Blackford R, Bollard T, Comerford A, Johnson ML, Sinha R, Vanatta L, Whiteley VJ, Schoeler NE, Ketogenic Dietitians Research Network · Molecular genetics and metabolism · 2026-06-18

Randomized clinical trial

51. Ketogenic Diet for Intensive Care Patients: A Scoping Review.

Bryła J, Szczupak M, Krupa-Nurcek S · Nutrients · 2026-06-16

Preclinical / mechanistic

52. Effect of the ketogenic diet on absence seizures in rats with genetic absence epilepsy.

Acikgoz NB, Toplu-Hocaoglu A, Yildirim BA, Yananli HR, Turkdogan D, Onat F · Epilepsy research · 2026-06-16

Review

53. Ketone bodies in kidney diseases: novel insights.

Dai W, Zhang W, Li H, Gao Y, Xiao L, Chen Y, He L · Frontiers in immunology · 2026-06-15

Case report / case series

54. Corpus Callosotomy in LIS1 Lissencephaly: Postoperative Ketogenic Diet-Related Metabolic Derangements and Feeding Intolerance.

Jalal A, Waggoner R, Lau J, George AJ, Salman H, Salman B · Cureus · 2026-06-13

Clinical trial / intervention

55. Fetal growth is driven by a bimodal fetal beta cell response and reshaped by a ketogenic diet in a mouse model of maternal diabetes.

Cohenshtam O, Zung A, Yu A, King H, Kotova P, Gover O, Magenheim Samuel I, Helman S, Walker MD, Ben-Zvi D, Kanarek N, Helman A · Diabetologia · 2026-06-09

Randomized clinical trial

56. Very low-carbohydrate ketogenic diet in treatment-naïve women with endometrial cancer and overweight: a randomized feasibility study.

Dantas E, Hootman KC, Moyer J, Tomberlin M, Curran K, Ramesh B, Price H, Kim J, McPherson AC, Hurd MA, Zhu YS, Plodkowski AJ, Nagase E, Tsomides A, Cuevas BM, Martin ML, Nguyen J, Bennetti G, Rodriguez GB, Chang K, Mezzancello M, Gardner GJ, Broach V, Mueller JJ, Sonoda Y, Zivanovic O, Leitao MM, Iasonos A, Soldan K, Carthew K, Hom V, Villamater FN, Chaari RR, Gorski K, Sigouros M, Aghajanian C, Elemento O, Cantley LC, Hopkins BD, Weigelt B, Ellenson LH, Hacker K, Abu-Rustum NR, Makker V, Goncalves MD · Nature communications · 2026-05-27

Randomized clinical trial

57. Ketogenic and Low-Carbohydrate Diets in Prostate Cancer: Metabolic Rationale, Preclinical Evidence, and Preliminary Clinical Data.

Manfrini S, Malgeri A, Mone C, Francesco LD, Pecora G, Mazzilli R, Defeudis G, Khazrai MY, Faggiano A · Journal of clinical medicine · 2026-05-20

Observational human study

58. Risks of using standard reference ranges for carbohydrate and lipid metabolism in low-carbohydrate diets: insights from ketogenic diet therapy in children with refractory epilepsy.

Matsui K, Mori M, Kumada T · Diabetology international · 2026-05-15

Review

59. Dukan diet, ketogenic diet and low glycemic index diet: Biochemical basis and metabolic consequences.

Muszalska A, Gaj Z, Roczyński B, Łompieś K, Polok I, Jaworska Z, Słowikowski BK · Nutrition (Burbank, Los Angeles County, Calif.) · 2026-05-12

Preclinical / mechanistic

60. Sex-specific systemic and brain metabolic responses to a standardized ketogenic diet in mice.

Lorin C, Diaceri G, Garcia M, Logette E, Markram H, Keller D · Lab animal · 2026-05-12

Preclinical / mechanistic

61. Effects of Ketogenic Diet on Behavioral, Metabolic, and Peripheral Tissue Changes in a Propylthiouracil-Induced Hypothyroidism Model.

Akkaya EC, Ilgin R, Kızıldağ S, Argon A, Hoşgörler F · Medical principles and practice : international journal of the Kuwait University, Health Science Centre · 2026-05-08

Randomized clinical trial

62. Effects of intermittent fasting combined with a ketogenic diet versus a hypocaloric diet on metabolic outcomes in adults with type 2 diabetes mellitus: A controlled clinical study.

Barrionuevo-Burgos E, García-García RM, Muñoz L, Arreguín-Coronado A · Nutrition and health · 2026-05-08

Systematic review / meta-analysis

63. Exploring the rise of the ketogenic dietary therapies for epilepsy in Latin America: A systematic review and meta-analysis.

Shibaki R, de Oliveira Franco MDNS, Camargo JSL, Citro GM, Ramos EM, Bruzzone M · Epilepsy research · 2026-04-30

Clinical trial / intervention

64. Macronutrient Composition and Genetic Background Determine the Response to a Ketogenic Diet.

Zhang Z, Moura-Assis A, Liu S, Millet A, Shaked J, Rajan D, Alwaseem H, Viscio MI, Molina H, Birsoy K, Friedman J · bioRxiv : the preprint server for biology · 2026-04-27

Clinical trial / intervention

65. Ketogenic metabolic therapy: low-carbohydrate interventions as novel neuroprotective strategies for cognitive dysfunction in diabetes.

Xun Y, Zeng W · Frontiers in aging neuroscience · 2026-04-24

Clinical trial / intervention

66. A ketogenic diet sensitizes pancreatic cancer to glutamine metabolism inhibitors.

Hajihassani O, Roichman A, Boyer JA, MacArthur M, Cordova R, Loftus A, Boutros CS, Hue JJ, Naji P, Tahhan S, Gallagher P, Beegan W, Shah D, Choi J, Manzoor N, Lei S, Kim C, Rathore M, Shah I, Lebo K, Cheng H, Mudigonda A, Hunter C, Zarei M, Alibeckoff S, Ji K, Graor H, Miyagi M, Vaziri-Gohar A, Brunengraber H, Wang R, Lund PJ, Rothermel LD, Rabinowitz JD, Winter JM · Cell reports. Medicine · 2026-04-23

Clinical trial / intervention

67. The Role of the Ketogenic Diet in Lung Cancer: Current Evidence and Future Perspectives.

Eleftheriadou ED, Kotoulas SC, Grammatikopoulou MG, Karakousi A, Maria A, Trimpali A, Tsalampounis X, Evangelidis P, Vamvakis A, Pataka A, Spyratos D · Cancers · 2026-04-17

Review

68. Ketogenic Diet in Children with Type 1 Diabetes: Parental Motivations and Potential Risks for Metabolic Health and Development.

Kovinthapillai R, Lan YY, Kędzia A, Niechciał E · Nutrients · 2026-04-15

Randomized clinical trial

69. Conversion Bariatric Surgery, Ketogenic Diet, and Intermittent Fasting in Bariatric Surgery Patients with Recurrent Weight Gain: a Prospective Randomized Controlled Trial.

Şen S, Erdem NZ, Durak D · Obesity surgery · 2026-04-11

Clinical trial / intervention

70. Emergence of hypomania and mania following initiation of a ketogenic diet: case series.

Palmer CM · Frontiers in nutrition · 2026-04-08

Clinical trial / intervention

71. Personalizing Obesity Treatment: Real-World Comparison of a Very-Low-Calorie Ketogenic Diet Versus a Whole-Food Mediterranean Ketogenic Diet.

Masi D, Spizzichini ML, Colonnello E, Vasquez Barahona D, Gnessi L, Gianfrilli D, Watanabe M · Metabolites · 2026-04-05

Preclinical / mechanistic

72. Divergent Liver and Kidney Metabolic Responses to Ketogenic, High-Fat, and Sucrose-Enriched Diets in Mice.

Grillo G, Vega N, Zaczek A, Selmi A, Chanon S, Vieille Marchiset A, Santillo A, Balcerczyk A, Strigini M, Pirola L · Nutrients · 2026-04-01

Other

73. Investigation of the implementation and utilization of ketogenic diet therapy in China : For the Commission on Standardized Development of Epilepsy Centers and Commission on Ketogenic Diet, China Association Against Epilepsy.

Xi W, Lin Y, Tian S, Liao J, Wang Y · Acta epileptologica · 2026-04-01

Clinical trial / intervention

74. Ketogenic Diet: A Metabolic Key to Overcoming Cancer Therapy Resistance.

Sulaiman SH, Omer RA, Barzani KIS, Jawhar ZH, Barzani HAH · Molecular nutrition & food research · 2026-03-29

Systematic review / meta-analysis

75. Metabolic, adherence, and sustainability outcomes of plant-based low-carbohydrate and ketogenic diets: A systematic review of clinical evidence.

Mazzola G, Rondanelli M, Cabrini C, Perna S · Nutrition (Burbank, Los Angeles County, Calif.) · 2026-03-24

Randomized clinical trial

76. Long-Term Fructose Intake Induces Moderate Liver Inflammation but Does not Overlap with the Detrimental Effects of the Ketogenic Diet on Hepatic Steatosis in Rats.

de Souza JG, Gurgel GG, Rodrigues FM, Braga RAM, Soares RAM, Lage LAPC, Soares IC, Levy D, Damasceno NRT · Inflammation · 2026-03-23

Preclinical / mechanistic

77. A ketogenic diet reduces hepatic alcohol metabolism and alcohol consumption in rats.

Elvig SK, McGinn A, Li X, Vendruscolo JCM, Gomez JL, Pawlosky R, Mackowiak B, Gonzalez L, King MT, Michaelides M, Gao B, Volkow ND, Koob GF, Wiers CE, Vendruscolo LF · Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026-03-20

Other

78. "Not always the magic bullet"-Insufficient seizure control by ketogenic dietary therapies in Glut1 Deficiency Syndrome.

Klepper J, Runkel E, Kiesel L · Epilepsia open · 2026-03-14

Randomized clinical trial

79. From clinical practice to mechanistic insights in ketogenic diets for epilepsy.

Figueroa AG, Joshi CN, Patel MN · The Lancet. Neurology · 2026-03-11

Other

80. Knowledge and attitudes toward ketogenic dietary therapy in adults with epilepsy.

Lutz MT, Alex M, Brandhoff F, Mayer T · Epilepsy & behavior : E&B · 2026-02-17

Clinical trial / intervention

81. Ketogenic diet modulates AMPK-mTOR pathway in breast cancer.

Luo Y, Li J, Yang Y, Yan L, Huang Z, Chen L, Zhao L, Wang J, Yang Y, Liu X, Yang X · The Journal of nutritional biochemistry · 2026-02-11

Clinical trial / intervention

82. Distinct effects of ketogenic and non-ketogenic weight-loss diets on hepatic steatosis and mitochondrial metabolism in MASLD.

Qadri SF, Porthan K, Dufour S, Lehtimäki TE, Petersen KF, Shulman GI, Yki-Järvinen H, Luukkonen PK · Journal of hepatology · 2026-02-06

Observational human study

83. Glucose transporter type 1 deficiency syndrome: Phenotypes, molecular findings, and ketogenic therapy implementation in Argentina.

Armeno ML, Massaro M, Boccoli J, Caballero E, Chacon S, Diz M, Espeche A, Fasulo L, Galarza N, Gonzalez L, Kobayashi V, Loos M, Semprino M, Veneruzzo G, Verini A, Caraballo R · Epileptic disorders : international epilepsy journal with videotape · 2026-02-02

Randomized clinical trial

84. Pharmacokinetic effects of a single dose nutritional ketone ester supplement on brain glucose and ketone metabolism in alcohol use disorder.

Li X, Young AJ, Shi Z, Byanyima J, Vesslee S, Reddy R, Pond T, Elliott M, Reddy R, Doot RK, van der Veen JW, Kranzler HR, Nanga RPR, Dubroff JG, Wiers CE · Psychiatry research. Neuroimaging · 2026-01-29

Randomized clinical trial

85. Effects of the ketogenic-caloric restricted diet on metabolic endotoxemia and metabolic health in adults with prediabetes: A randomized controlled trial.

Jawamis A, Al-Domi H, Sarayreh NA · Nutrition (Burbank, Los Angeles County, Calif.) · 2026-01-23

Clinical trial / intervention

86. Effect of a non-energy restricted ketogenic diet on cognition in sedentary healthy young adults.

Khattak M, Habib SH, Irfan M · Physiology international · 2026-01-20

Clinical trial / intervention

87. The ketogenic diet is not for everyone: contraindications, side effects, and drug interactions.

Dyńka D, Rodzeń Ł, Rodzeń M, Łojko D, Karakuła-Juchnowicz H, Ede G, Grzywacz Ż, Antosik K, Sethi S, Unwin D · Annals of medicine · 2026-01-04

Randomized clinical trial

88. Ketogenic diet attenuates high fat diet induced obesity in rats: insights into hepatic and intestinal tissues.

Abo El-Magd NF, Ramadan NM, Hassan YF, Mahmoud AM, Azzam MM, Eraky SM · The Journal of nutritional biochemistry · 2025-12-13

Randomized clinical trial

89. Metabolic Improvements with a Ketogenic Diet Correlate with Symptom Improvement in Psychosis: A Randomized Controlled Trial.

Abram SV, Kyner JM, Vu A, Naeem Z, Sethi S, Jacob MS, Fryer SL, Mathalon DH, Ford JM · Schizophrenia bulletin · 2025-11-25

Observational human study

90. Benefits and adverse effects of ketogenic diet treatment in pediatric patients with inborn errors of metabolism.

Wesół-Kucharska D, Kaczor MA, Emczyńska-Seliga EEV · Advances in clinical and experimental medicine : official organ Wroclaw Medical University · 2025-11-22

Clinical trial / intervention

91. Link between emotional and external eating behaviors, peripheral neuropeptide Y, and β-hydroxybutyrate in participants with obesity on 12-week ketogenic diet.

Černelič-Bizjak M, Kenig S, Petelin A, Jenko-Pražnikar Z, Mohorko N · Nutrition and health · 2023-02-03

Review

92. Ketogenic diet: Assessing YouTube video information using quality, reliability, and text analytics methods.

Rana A, Arora M · Nutrition and health · 2023-08-09

Review

93. Exploring ketogenic diet resistance in glucose transporter type 1 deficiency syndrome: A comprehensive review and critical appraisal.

Falsaperla R, Sortino V, Kluger GJ, Herberhold T, Rüegger A, Striano P, Ruggieri M, Klepper J, Ramantani G · Epilepsia open · 2024-12-06

Clinical trial / intervention

94. Effects of the Ketogenic Diet on Microbiota Composition and Short-Chain Fatty Acids in Women with Overweight/Obesity.

Güzey Akansel M, Baş M, Gençalp C, Kahrıman M, Şahin E, Öztürk H, Gür G, Gür C · Nutrients · 2024-12-19

Review

95. The Cardioprotective Effects of Nutritional Ketosis: Mechanisms and Clinical Implications.

Venturini C, Mancinelli L, Matacchione G, Olivieri F, Antonicelli R · Nutrients · 2024-12-05

Systematic review / meta-analysis

96. Exogenous Ketones in Cardiovascular Disease and Diabetes: From Bench to Bedside.

Kansakar U, Nieves Garcia C, Santulli G, Gambardella J, Mone P, Jankauskas SS, Lombardi A · Journal of clinical medicine · 2024-12-04

Randomized clinical trial

97. Randomized Crossover Trial of 2-Week Ketone Ester Treatment in Patients With Type 2 Diabetes and Heart Failure With Preserved Ejection Fraction.

Gopalasingam N, Berg-Hansen K, Christensen KH, Ladefoged BT, Poulsen SH, Andersen MJ, Borlaug BA, Nielsen R, Møller N, Wiggers H · Circulation · 2024-08-20

Randomized clinical trial

98. 5-Year effects of a novel continuous remote care model with carbohydrate-restricted nutrition therapy including nutritional ketosis in type 2 diabetes: An extension study.

McKenzie AL, Athinarayanan SJ, Van Tieghem MR, Volk BM, Roberts CGP, Adams RN, Volek JS, Phinney SD, Hallberg SJ · Diabetes research and clinical practice · 2024-10-20

Preclinical / mechanistic

99. Transcriptional cascades during fasting amplify gluconeogenesis and instigate a secondary wave of ketogenic gene transcription.

Goldberg D, Buchshtab N, Charni-Natan M, Goldstein I · Liver international : official journal of the International Association for the Study of the Liver · 2024-08-20

Review

100. Ketogenic Diet: A Review of Composition Diversity, Mechanism of Action and Clinical Application.

Malinowska D, Żendzian-Piotrowska M · Journal of nutrition and metabolism · 2024-10-18

Preclinical / mechanistic

101. Oral Administration of a Novel, Synthetic Ketogenic Compound Elevates Blood β-Hydroxybutyrate Levels in Mice in Both Fasted and Fed Conditions.

Soliven MA, Rogers CQ, Williams MS, Thomas NN, Turos E, D'Agostino DP · Nutrients · 2024-10-18

Randomized clinical trial

102. Effect of weight-maintaining ketogenic diet on glycemic control and insulin sensitivity in obese T2D subjects.

Merovci A, Finley B, Hansis-Diarte A, Neppala S, Abdul-Ghani MA, Cersosimo E, Triplitt C, DeFronzo RA · BMJ open diabetes research & care · 2024-10-18

Systematic review / meta-analysis

103. Mapping the evolution and impact of ketogenic diet research on diabetes management: a comprehensive bibliometric analysis from 2005 to 2024.

Li Z, Li A, Liu P, Zhang B, Yan Y · Frontiers in nutrition · 2024-10-15

Preclinical / mechanistic

104. A ketogenic diet, regardless of fish oil content, does not affect glucose homeostasis or muscle insulin response in male rats.

Budd JM, Notaro NM, MacLeod B, Mutch DM, Dyck DJ · American journal of physiology. Endocrinology and metabolism · 2024-08-14

Preclinical / mechanistic

105. Ketone bodies rescue T cell impairments induced by low glucose availability.

Ferrari A, Filoni J, Di Dedda C, Piemonti L, Monti P · European journal of nutrition · 2024-08-06

Randomized clinical trial

106. A 3-Week Ketogenic Diet Increases Skeletal Muscle Insulin Sensitivity in Individuals With Obesity: A Randomized Controlled Crossover Trial.

Luong TV, Pedersen MGB, Abild CB, Lauritsen KM, Kjærulff MLG, Møller N, Gormsen LC, Søndergaard E · Diabetes · 2024-02-28

Preclinical / mechanistic

107. The gut microbiota changed by ketogenic diets contribute to glucose intolerance rather than lipid accumulation.

Li W, Gong M, Wang Z, Pan H, Li Y, Zhang C · Frontiers in endocrinology · 2024-09-27

Preclinical / mechanistic

108. Comparative Efficacy of Low-Carbohydrate and Ketogenic Diets on Diabetic Retinopathy and Oxidative Stress in High-Fat Diet-Induced Diabetic Rats.

Jawharji MT, Alshammari GM, Binobead MA, Albanyan NM, Al-Harbi LN, Yahya MA · Nutrients · 2024-09-12

Randomized clinical trial

109. Ketogenic diet but not free-sugar restriction alters glucose tolerance, lipid metabolism, peripheral tissue phenotype, and gut microbiome: RCT.

Hengist A, Davies RG, Walhin JP, Buniam J, Merrell LH, Rogers L, Bradshaw L, Moreno-Cabañas A, Rogers PJ, Brunstrom JM, Hodson L, van Loon LJC, Barton W, O'Donovan C, Crispie F, O'Sullivan O, Cotter PD, Proctor K, Betts JA, Koumanov F, Thompson D, Gonzalez JT · Cell reports. Medicine · 2024-08-05

Preclinical / mechanistic

110. Sex- and Age-Specific Differences in Mice Fed a Ketogenic Diet.

Sprankle KW, Knappenberger MA, Locke EJ, Thompson JH, Vinovrski MF, Knapsack K, Kolwicz SC · Nutrients · 2024-08-16

Randomized clinical trial

111. Ketogenic Diet and Its Potential Role in Preventing Type 2 Diabetes Mellitus and Its Complications: A Narrative Review of Randomized Controlled Trials.

Alluwyam AH, Estrella ED · Cureus · 2024-08-08

Case report / case series

112. Euglycemic diabetic ketoacidosis in a patient with new-onset type 1 diabetes following a ketogenic diet: a potential risk of a dangerous dietary trend.

Helvaci BC, Erdogan BT, Ozdemir D, Topaloglu O, Cakir B · Archives of endocrinology and metabolism · 2024-08-05

Case report / case series

113. Efficacy and Safety of Long-term Ketogenic Diet Therapy in a Patient With Type 1 Diabetes.

Koutnik AP, Klein S, Robinson AT, Watso JC · JCEM case reports · 2024-07-10

Case report / case series

114. Resolution of Persistent Chylothorax With a Ketogenic Diet: A Case Report.

Redick JC, Kesslering C · Cureus · 2024-07-09

Preclinical / mechanistic

115. The Effects of Ketogenic Diet on Brain Gene Expressions in Type 2 Diabetes Background.

Ren Q, Fu J, Duan X, Sun L, Mu Z, Liang W, Li Y, Wang Z, Xiu S · Neuroscience · 2024-05-10

Clinical trial / intervention

116. Long-term ketogenic diet causes hyperlipidemia, liver dysfunction, and glucose intolerance from impaired insulin trafficking and secretion in mice.

Gallop MR, Vieira RFL, Matsuzaki ET, Mower PD, Liou W, Smart FE, Roberts S, Evason KJ, Holland WL, Chaix A · bioRxiv : the preprint server for biology · 2024-06-17

Randomized clinical trial

117. Effect of Acute Nutritional Ketosis on Circulating Levels of Growth Differentiation Factor 15: Findings from a Cross-Over Randomised Controlled Trial.

Charles S, Liu Y, Bharmal SH, Kimita W, Petrov MS · Biomolecules · 2024-06-06

Case report / case series

118. Introduction and modification of the ketogenic diet in an adult patient with glucose transporter 1 deficiency syndrome.

Nabatame S, Kishimoto K, Mano T · Epileptic disorders : international epilepsy journal with videotape · 2024-03-16

Clinical trial / intervention

119. Dietary Influence on Drug Efficacy: A Comprehensive Review of Ketogenic Diet-Pharmacotherapy Interactions.

Marinescu SCN, Apetroaei MM, Nedea MII, Arsene AL, Velescu BȘ, Hîncu S, Stancu E, Pop AL, Drăgănescu D, Udeanu DI · Nutrients · 2024-04-19

Randomized clinical trial

120. A randomized open-label, observational study of the novel ketone ester, bis octanoyl (R)-1,3-butanediol, and its acute effect on ß-hydroxybutyrate and glucose concentrations in healthy older adults.

Stephens EB, Senadheera C, Roa-Diaz S, Peralta S, Alexander L, Silverman-Martin W, Yukawa M, Morris J, Johnson JB, Newman JC, Stubbs BJ · medRxiv : the preprint server for health sciences · 2024-04-18

Preclinical / mechanistic

121. Ketogenic diet ameliorates high-fat diet-induced insulin resistance in mouse skeletal muscle by alleviating endoplasmic reticulum stress.

Ma Q, Jiang L, You Y, Ni H, Ma L, Lin X, Wang Z, Yan W, Xiao X, Li X, Li J · Biochemical and biophysical research communications · 2024-02-05

Case report / case series

122. GLUT-1DS resistant to ketogenic diet: from clinical feature to in silico analysis. An exemplificative case report with a literature review.

Falsaperla R, Sortino V, Vitaliti G, Privitera GF, Ruggieri M, Fusto G, Pappalardo XG · Neurogenetics · 2024-01-08

Review

123. The impact of ketogenic diet on some metabolic and non-metabolic diseases: Evidence from human and animal model experiments.

Galali Y, Zebari SMS, Aj Jabbar A, Hashm Balaky H, Sadee BA, Hassanzadeh H · Food science & nutrition · 2024-01-08

Guideline / consensus

124. Ketogenic nutritional therapy (KeNuT)-a multi-step dietary model with meal replacements for the management of obesity and its related metabolic disorders: a consensus statement from the working group of the Club of the Italian Society of Endocrinology (SIE)-diet therapies in endocrinology and metabolism.

Barrea L, Caprio M, Camajani E, Verde L, Perrini S, Cignarelli A, Prodam F, Gambineri A, Isidori AM, Colao A, Giorgino F, Aimaretti G, Muscogiuri G · Journal of endocrinological investigation · 2024-01-18

Clinical trial / intervention

125. Clinical effectiveness and cost-impact after 2 years of a ketogenic diet and virtual coaching intervention for patients with diabetes.

Strombotne KL, Lum J, Pizer SD, Figueroa S, Frakt AB, Conlin PR · Diabetes, obesity & metabolism · 2023-12-11

Randomized clinical trial

126. The effect of acute and 14-day exogenous ketone supplementation on glycemic control in adults with type 2 diabetes: two randomized controlled trials.

Falkenhain K, Oliveira BF, Islam H, Neudorf H, Cen HH, Johnson JD, Madden K, Singer J, Walsh JJ, Little JP · American journal of physiology. Endocrinology and metabolism · 2023-11-22

Review

127. Does a Ketogenic Diet Have a Place Within Diabetes Clinical Practice? Review of Current Evidence and Controversies.

Firman CH, Mellor DD, Unwin D, Brown A · Diabetes therapy : research, treatment and education of diabetes and related disorders · 2023-11-15

Preclinical / mechanistic

128. Role of insulin resistance and leptin in the effect of intermittent feeding with a high-protein ketogenic diet on body composition in rats.

Eyikudamaci G, Ege H, Ensen N, Yelmen N · Nutrition (Burbank, Los Angeles County, Calif.) · 2023-09-07

Review

129. A Potential Role for the Ketogenic Diet in Alzheimer's Disease Treatment: Exploring Pre-Clinical and Clinical Evidence.

Oliveira TPD, Morais ALB, Dos Reis PLB, Palotás A, Vieira LB · Metabolites · 2023-12-29

Randomized clinical trial

130. A pilot study of alternative substrates in the critically Ill subject using a ketogenic feed.

McNelly A, Langan A, Bear DE, Page A, Martin T, Seidu F, Santos F, Rooney K, Liang K, Heales SJ, Baldwin T, Alldritt I, Crossland H, Atherton PJ, Wilkinson D, Montgomery H, Prowle J, Pearse R, Eaton S, Puthucheary ZA · Nature communications · 2023-12-15

Systematic review / meta-analysis

131. The effects of the ketogenic diet for the management of type 2 diabetes mellitus: A systematic review and meta-analysis of recent studies.

Choy KYC, Louie JCY · Diabetes & metabolic syndrome · 2023-11-15

Randomized clinical trial

132. Ketogenic propensity is differentially related to lipid-induced hepatic and peripheral insulin resistance.

Mey JT, Vandagmansar B, Dantas WS, Belmont KP, Axelrod CL, Kirwan JP · Acta physiologica (Oxford, England) · 2023-10-16

Observational human study

133. Effects of a two meals-a-day ketogenic diet on newly diagnosed obese patients with type 2 diabetes mellitus: A retrospective observational study.

Li S, Yuan S, Lin G, Zhang J · Medicine · 2023-11-01

Preclinical / mechanistic

134. Ketogenic diet influence on the elemental homeostasis of internal organs is gender dependent.

Kawon K, Rugiel M, Setkowicz Z, Matusiak K, Kubala-Kukus A, Stabrawa I, Szary K, Rauk Z, Chwiej J · Scientific reports · 2023-10-27

Review

135. Ketone Bodies in Diabetes Mellitus: Friend or Foe?

Veneti S, Grammatikopoulou MG, Kintiraki E, Mintziori G, Goulis DG · Nutrients · 2023-10-16

Randomized clinical trial

136. Corrigendum: Weight, insulin resistance, blood lipids, and diet quality changes associated with ketogenic and ultra low-fat dietary patterns: a secondary analysis of the DIETFITS randomized clinical trial.

Aronica L, Landry MJ, Rigdon J, Gardner CD · Frontiers in nutrition · 2023-10-09

Randomized clinical trial

137. Type 1 diabetes and low carbohydrate diets-Defining the degree of nutritional ketosis.

Ozoran H, Matheou M, Dyson P, Karpe F, Tan GD · Diabetic medicine : a journal of the British Diabetic Association · 2023-07-26

Randomized clinical trial

138. Adherence to ketogenic diet in lifestyle interventions in adults with overweight or obesity and type 2 diabetes: a scoping review.

Li S, Du Y, Meireles C, Sharma K, Qi L, Castillo A, Wang J · Nutrition & diabetes · 2023-09-14

Preclinical / mechanistic

139. Safe use of the ketogenic diet in an infant with microcephaly, epilepsy, and diabetes syndrome: a case report.

Zegarra WA, Gallentine WB, Ruzhnikov MR, McAndrews CA, Gloyn AL, Addala A · BMC pediatrics · 2023-09-09

Clinical trial / intervention

140. Low-Calorie Ketogenic Diet: Potential Application in the Treatment of Polycystic Ovary Syndrome in Adolescents.

Calcaterra V, Cena H, Sottotetti F, Hruby C, Madini N, Zelaschi N, Zuccotti G · Nutrients · 2023-08-15

Review

141. Effects of very low carbohydrate ketogenic diets on skeletal health.

Best CM, Hsu S · Current opinion in endocrinology, diabetes, and obesity · 2023-05-02

Clinical trial / intervention

142. Comparison of the Ketogenic Ratio of Macronutrients With the Low-Carbohydrate Diet Score and Their Association With Risk of Type 2 Diabetes in Postmenopausal Women: A Secondary Analysis of the Women's Health Initiative.

Titcomb TJ, Liu B, Wahls TL, Snetselaar LG, Shadyab AH, Tabung FK, Saquib N, Arcan C, Tinker LF, Wallace RB, Bao W · Journal of the Academy of Nutrition and Dietetics · 2022-12-20

Observational human study

143. 2:1 ketogenic diet and low-glycemic-index diet for the treatment of chronic and episodic migraine: a single-center real-life retrospective study.

Tereshko Y, Dal Bello S, Di Lorenzo C, Pez S, Pittino A, Sartor R, Filippi F, Lettieri C, Belgrado E, Garbo R, Merlino G, Gigli GL, Valente M · The journal of headache and pain · 2023-07-28

Review

144. The Effects of Ketogenic Diet on Insulin Sensitivity and Weight Loss, Which Came First: The Chicken or the Egg?

Paoli A, Bianco A, Moro T, Mota JF, Coelho-Ravagnani CF · Nutrients · 2023-07-12

Randomized clinical trial

145. Weight, insulin resistance, blood lipids, and diet quality changes associated with ketogenic and ultra low-fat dietary patterns: a secondary analysis of the DIETFITS randomized clinical trial.

Aronica L, Landry MJ, Rigdon J, Gardner CD · Frontiers in nutrition · 2023-07-12

Other

146. Combination of triheptanoin with the ketogenic diet in Glucose transporter type 1 deficiency (G1D).

Avila A, Málaga I, Sirsi D, Kayani S, Primeaux S, Kathote GA, Jakkamsetti V, Kallem RR, Putnam WC, Park JY, Shinnar S, Pascual JM · Scientific reports · 2023-06-02

Observational human study

147. Role of EEG as a monitoring tool in patients with glucose transporter type I deficiency syndrome (GLUT1-DS) on ketogenic diet.

Toro-Perez J, Healy S, Sell E, Bulusu S, Whiting S · Epileptic disorders : international epilepsy journal with videotape · 2023-05-06

Observational human study

148. Regional brain glucose metabolism is differentially affected by ketogenic diet: a human semiquantitative positron emission tomography.

Horowitz T, Doche E, Philip M, Cammilleri S, Suissa L, Guedj E · European journal of nuclear medicine and molecular imaging · 2023-03-03

Clinical trial / intervention

149. Long-term follow-up of nutritional status in children with GLUT1 Deficiency Syndrome treated with classic ketogenic diet: a 5-year prospective study.

De Amicis R, Leone A, Pellizzari M, Foppiani A, Battezzati A, Lessa C, Tagliabue A, Ferraris C, De Giorgis V, Olivotto S, Previtali R, Veggiotti P, Bertoli S · Frontiers in nutrition · 2023-05-24

Clinical trial / intervention

150. Hepatokines, bile acids and ketone bodies are novel Hormones regulating energy homeostasis.

Garruti G, Baj J, Cignarelli A, Perrini S, Giorgino F · Frontiers in endocrinology · 2023-05-19

Preclinical / mechanistic

151. A ketogenic diet improves vascular hyperpermeability in type 2 diabetic mice by downregulating vascular pescadillo1 expression.

Wang S, Zhou J, Lu J, Lin Y, Liu S, Chen K · Journal of cellular and molecular medicine · 2023-04-15

Clinical trial / intervention

152. [Ketogenic diet improves low temperature tolerance in mice by up-regulating PPARα in the liver and brown adipose tissue].

Li CH, Zhang W, Wang PP, Zhang PF, An J, Yang HY, Gao F, Wu GL, Zhang X · Sheng li xue bao : [Acta physiologica Sinica] · 2023-04-25

Randomized clinical trial

153. Fasting and diurnal blood ketonemia and glycemia responses to a six-week, energy-controlled ketogenic diet, supplemented with racemic R/S-BHB salts.

Buga A, Kackley ML, Crabtree CD, Bedell TN, Robinson BT, Stoner JT, Decker DD, Hyde PN, LaFountain RA, Brownlow ML, O'Connor A, Krishnan D, McElroy CA, Kraemer WJ, Volek JS · Clinical nutrition ESPEN · 2023-02-04

Other

154. Intermittent fasting with ketogenic diet: A combination approach for management of chronic diseases.

Arora N, Pulimamidi S, Yadav H, Jain S, Glover J, Dombrowski K, Hernandez B, Sarma AK, Aneja R · Clinical nutrition ESPEN · 2023-01-28

Review

155. Low carbohydrate high fat ketogenic diets on the exercise crossover point and glucose homeostasis.

Noakes TD, Prins PJ, Volek JS, D'Agostino DP, Koutnik AP · Frontiers in physiology · 2023-03-28

Randomized clinical trial

156. Acute Insulin Secretory Effects of a Classic Ketogenic Meal in Healthy Subjects: A Randomized Cross-Over Study.

Battezzati A, Foppiani A, Leone A, De Amicis R, Spadafranca A, Mari A, Bertoli S · Nutrients · 2023-02-23

Clinical trial / intervention

157. Effect of the Ketogenic Diet on the Prophylaxis and Treatment of Diabetes Mellitus: A Review of the Meta-Analyses and Clinical Trials.

Dyńka D, Kowalcze K, Ambrozkiewicz F, Paziewska A · Nutrients · 2023-01-18

Clinical trial / intervention

158. [Beneficial effects of ketogenic diet for Alzheimer's disease management].

Charlot A, Lernould A, Plus I, Zoll J · Biologie aujourd'hui · 2023-11-29

Preclinical / mechanistic

159. Ketogenic diet modulates cardiac metabolic dysregulation in streptozocin-induced diabetic rats.

Trang NN, Lee TW, Kao YH, Chao TF, Lee TI, Chen YJ · The Journal of nutritional biochemistry · 2022-09-29

Review

160. Low-Carbohydrate Ketogenic Diet for Improvement of Glycemic Control: Mechanism of Action of Ketosis and Beneficial Effects.

Sakr HF, Sirasanagandla SR, Das S, Bima AI, Elsamanoudy AZ · Current diabetes reviews · 2021-12-20

Systematic review / meta-analysis

161. A Ketogenic Diet is Effective in Improving Insulin Sensitivity in Individuals with Type 2 Diabetes.

Skow SL, Jha RK · Current diabetes reviews · 2021-12-13

Preclinical / mechanistic

162. Still Excited, but Less Aroused-The Effects of Nutritional Ketosis on Epinephrine Response and Hypothalamic Orexin Neuron Activation Following Recurrent Hypoglycemia in Diabetic Rats.

Nedoboy PE, Farnham MM · Metabolites · 2022-12-27

Other

163. Correction to: Gardner et al. Effect of a ketogenic diet versus Mediterranean diet on glycated hemoglobin in individuals with prediabetes and type 2 diabetes mellitus: The interventional Keto-Med randomized crossover trial.

The American journal of clinical nutrition · 2022-11-10

Clinical trial / intervention

164. Ketogenic Diet Increases Serum and White Adipose Tissue SIRT1 Expression in Mice.

Tozzi R, Campolo F, Baldini E, Venneri MA, Lubrano C, Ulisse S, Gnessi L, Mariani S · International journal of molecular sciences · 2022-12-13

Randomized clinical trial

165. Intractable Seizures in Children With Type 1 Diabetes: Implications of the Ketogenic Diet.

Vidmar KK, Pollock AJ · WMJ : official publication of the State Medical Society of Wisconsin · 2023-01-13

Preclinical / mechanistic

166. Requirement of hepatic pyruvate carboxylase during fasting, high fat, and ketogenic diet.

Selen ES, Rodriguez S, Cavagnini KS, Kim HB, Na CH, Wolfgang MJ · The Journal of biological chemistry · 2022-10-28

Systematic review / meta-analysis

167. Very low carbohydrate (ketogenic) diets in type 2 diabetes: A systematic review and meta-analysis of randomized controlled trials.

Parry-Strong A, Wright-McNaughton M, Weatherall M, Hall RM, Coppell KJ, Barthow C, Krebs JD · Diabetes, obesity & metabolism · 2022-09-05

Other

168. The detection of infectious endocarditis may be enhanced by a repeat FDG-PET while maintaining patients on a ketogenic diet.

Germaini M, Boursier C, Goehringer F, Selton-Suty C, Lefevre B, Roch V, Imbert L, Claudin M, Chevalier E, Marie PY · Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2022-02-22

Review

169. Comprehensive nutrient consumption estimation and metabolic profiling during ketogenic diet and relationship with myocardial glucose uptake on FDG-PET.

Selvaraj S, Seidelmann SB, Soni M, Bhattaru A, Margulies KB, Shah SH, Dugyala S, Qian C, Pryma DA, Arany Z, Kelly DP, Chirinos JA, Bravo PE · European heart journal. Cardiovascular Imaging · 2021-10-05

Other

170. Dynamics of Gut Microbiota and Clinical Variables after Ketogenic and Mediterranean Diets in Drug-Naïve Patients with Type 2 Diabetes Mellitus and Obesity.

Deledda A, Palmas V, Heidrich V, Fosci M, Lombardo M, Cambarau G, Lai A, Melis M, Loi E, Loviselli A, Manzin A, Velluzzi F · Metabolites · 2022-11-10

Other

171. The ketogenic diet maintains insulin sensitivity and inhibits lipid accumulation in the liver.

King AN, Notaro NM · The Journal of physiology · 2022-10-06

Preclinical / mechanistic

172. Ketogenic diet administration to mice after a high-fat-diet regimen promotes weight loss, glycemic normalization and induces adaptations of ketogenic pathways in liver and kidney.

Nasser S, Solé T, Vega N, Thomas T, Balcerczyk A, Strigini M, Pirola L · Molecular metabolism · 2022-08-20

Systematic review / meta-analysis

173. Clinical Assessment of Intermittent Fasting With Ketogenic Diet in Glycemic Control and Weight Reduction in Patients With Type II Diabetes Mellitus: A Systematic Review and Meta-Analysis.

Zaki HA, Iftikhar H, Abdalrubb A, Al-Marri NDR, Abdelrahim MG, Fayed M, Elgassim MAM, Elarref MA · Cureus · 2022-10-30

Other

174. Italian Ketogenic Mediterranean Diet in Overweight and Obese Patients with Prediabetes or Type 2 Diabetes.

Ivan CR, Messina A, Cibelli G, Messina G, Polito R, Losavio F, Torre E, Monda V, Monda M, Quiete S, Casula E, Napoli N, Defeudis G · Nutrients · 2022-10-18

Other

175. Re: Effect of a ketogenic diet versus Mediterranean diet on glycated hemoglobin in individuals with prediabetes and type 2 diabetes mellitus: the interventional Keto-Med randomized crossover trial.

Kalayjian T, Westman EC · The American journal of clinical nutrition · 2022-08-18

Review

176. The gut microbiome as possible mediator of the beneficial effects of very low calorie ketogenic diet on type 2 diabetes and obesity: a narrative review.

Defeudis G, Rossini M, Khazrai YM, Pipicelli AMV, Brucoli G, Veneziano M, Strollo F, AMD-SID-SIEDP-Lifestyle Study Group Lazio, Bellia A, Bitterman O, Lauro D, Mora D, Santarelli E · Eating and weight disorders : EWD · 2022-07-01

Clinical trial / intervention

177. Effects of Ketogenic Diet on Muscle Metabolism in Health and Disease.

Yakupova EI, Bocharnikov AD, Plotnikov EY · Nutrients · 2022-09-16

Guideline / consensus

178. Effect of a ketogenic diet versus Mediterranean diet on glycated hemoglobin in individuals with prediabetes and type 2 diabetes mellitus: The interventional Keto-Med randomized crossover trial.

Gardner CD, Landry MJ, Perelman D, Petlura C, Durand LR, Aronica L, Crimarco A, Cunanan KM, Chang A, Dant CC, Robinson JL, Kim SH · The American journal of clinical nutrition · 2021-12-18

Clinical trial / intervention

179. The ketogenic diet prevents steatosis and insulin resistance by reducing lipogenesis, diacylglycerol accumulation and protein kinase C activity in male rat liver.

Jani S, Da Eira D, Stefanovic M, Ceddia RB · The Journal of physiology · 2022-09-04

Systematic review / meta-analysis

180. Effects of very low-carbohydrate ketogenic diet on lipid metabolism in patients with type II diabetes mellitus: a meta-analysis.

Li M, Yuan J · Nutricion hospitalaria · 2022-03-05

Systematic review / meta-analysis

181. Ketogenic Diet Benefits to Weight Loss, Glycemic Control, and Lipid Profiles in Overweight Patients with Type 2 Diabetes Mellitus: A Meta-Analysis of Randomized Controlled Trails.

Zhou C, Wang M, Liang J, He G, Chen N · International journal of environmental research and public health · 2022-08-22

Review

182. Helpful or harmful? The impact of the ketogenic diet on eating disorder outcomes in type 1 diabetes mellitus.

Schneider S, Biggerstaff DL, Barber TM · Expert review of endocrinology & metabolism · 2022-06-24

Clinical trial / intervention

183. Fasting or the short-term consumption of a ketogenic diet protects against antipsychotic-induced hyperglycaemia in mice.

Shamshoum H, Medak KD, McKie GL, Hahn MK, Wright DC · The Journal of physiology · 2022-05-17

Case report / case series

184. Lactation ketoacidosis induced by breastfeeding while on a ketogenic diet.

Osborne KC, Oliver JJ · The American journal of emergency medicine · 2022-02-27

Systematic review / meta-analysis

185. A Comparative Study Evaluating the Effectiveness Between Ketogenic and Low-Carbohydrate Diets on Glycemic and Weight Control in Patients With Type 2 Diabetes Mellitus: A Systematic Review and Meta-Analysis.

Zaki HA, Iftikhar H, Bashir K, Gad H, Samir Fahmy A, Elmoheen A · Cureus · 2022-05-31

Review

186. Possible Nonneurological Health Benefits of Ketogenic Diet: Review of Scientific Reports over the Past Decade.

Daria Gołąbek K, Regulska-Ilow B · Journal of obesity · 2022-05-27

Case report / case series

187. Positive impact of a modified Atkins diet on cognition, seizure control, and abnormal movements in an adult with glucose transporter type 1 deficiency syndrome: case report.

Diaz-Arias LA, Henry-Barron BJ, Buchholz A, Cervenka MC · Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2022-03-03

Observational human study

188. A Low-Carbohydrate, High-Fat Ketogenic Diet Program Implemented by an Interdisciplinary Primary Care Team Improves Markers of Cardiometabolic Health in Adults With Type 2 Diabetes: A Retrospective Secondary Analysis.

Neudorf H, Mindrum M, Mindrum C, Durrer C, Little JP · Canadian journal of diabetes · 2021-09-08

Clinical trial / intervention

189. A ketogenic diet reduces mechanical allodynia and improves epidermal innervation in diabetic mice.

Enders J, Swanson MT, Ryals J, Wright DE · Pain · 2021-03-30

Review

190. Role of ketone bodies in diabetes-induced dementia: sirtuins, insulin resistance, synaptic plasticity, mitochondrial dysfunction, and neurotransmitter.

Chung JY, Kim OY, Song J · Nutrition reviews · 2021-12-28

Systematic review / meta-analysis

191. Effect of a very low-carbohydrate ketogenic diet vs recommended diets in patients with type 2 diabetes: a meta-analysis.

Rafiullah M, Musambil M, David SK · Nutrition reviews · 2021-08-03

Other

192. Monitoring Glucose Concentrations in Children with Epilepsy on a Ketogenic Diet.

Schiller K, Avigdor T, Kortas A, Kunz M, Unterholzner G, Klingelhöfer M, Rauchenzauner M · Healthcare (Basel, Switzerland) · 2022-01-27

Case report / case series

193. Severe Hypertriglyceridemia-Induced Necrotizing Pancreatitis Associated With Ketogenic Diet in a Well-Controlled Patient With Type 2 Diabetes Mellitus.

Chan JT, Mude PJ, Canfield W, Makhija J, Yap JEL · Cureus · 2022-01-02

Other

194. Severe type 2 diabetes (T2D) remission using a very low-calorie ketogenic diet (VLCKD).

Correa LL, Medeiros de Sousa PA, Dinis L, Carloto LB, Nuñez-Garcia M, Sajoux I, Senhorini S · Endocrinology, diabetes & metabolism case reports · 2022-09-01

Review

195. Ketogenic Diet: A Promising Neuroprotective Composition for Managing Alzheimer's Diseases and its Pathological Mechanisms.

Sridharan B, Lee MJ · Current molecular medicine · 2021-04-06

Preclinical / mechanistic

196. Impact of ketogenic diet and ketone diester supplementation on body weight, blood glucose, and ketones in Sprague Dawley rats fed over two weeks.

Modica LCM, Flores-Felix K, Casachahua LJD, Asquith P, Tschiffely A, Ciarlone S, Ahlers ST · Food chemistry. Molecular sciences · 2021-06-10

Systematic review / meta-analysis

197. Effect of Ketogenic Diet on Quality of Life in Adults with Chronic Disease: A Systematic Review of Randomized Controlled Trials.

Abboud M, AlAnouti F, Georgaki E, Papandreou D · Nutrients · 2021-12-14

Review

198. Ketone bodies: from enemy to friend and guardian angel.

Kolb H, Kempf K, Röhling M, Lenzen-Schulte M, Schloot NC, Martin S · BMC medicine · 2021-12-09

Clinical trial / intervention

199. Effectiveness of a ketogenic diet and virtual coaching intervention for patients with diabetes: A difference-in-differences analysis.

Strombotne KL, Lum J, Ndugga NJ, Utech AE, Pizer SD, Frakt AB, Conlin PR · Diabetes, obesity & metabolism · 2021-08-19

Clinical trial / intervention

200. Can older patients adopt and maintain a ketogenic diet? An observational study in support of clinical trials in older patients.

Almodallal Y, Cook K, Lammert LM, Lee M, Le-Rademacher JG, Jatoi A · Medicine · 2020-12-15

Review

201. Alzheimer's Disease and Type 2 Diabetes Mellitus: The Use of MCT Oil and a Ketogenic Diet.

Takeishi J, Tatewaki Y, Nakase T, Takano Y, Tomita N, Yamamoto S, Mutoh T, Taki Y · International journal of molecular sciences · 2021-11-15

Review

202. Ketogenic Diets and Cardio-Metabolic Diseases.

Zhang W, Guo X, Chen L, Chen T, Yu J, Wu C, Zheng J · Frontiers in endocrinology · 2021-11-02

Review

203. Brief Literature Review: Glycemic Control With Ketogenic Diet in People With Diabetes.

Gordon PM, Clements JN · Diabetes spectrum : a publication of the American Diabetes Association · 2021-09-15

Other

204. Reply to Berk et al. Comment on "Moriconi et al. Very-Low-Calorie Ketogenic Diet as a Safe and Valuable Tool for Long-Term Glycemic Management in Patients with Obesity and Type 2 Diabetes. Nutrients 2021, 13, 758".

Moriconi E, Camajani E, Fabbri A, Lenzi A, Caprio M · Nutrients · 2021-10-18

Other

205. Comment on Moriconi et al. Very-Low-Calorie Ketogenic Diet as a Safe and Valuable Tool for Long-Term Glycemic Management in Patients with Obesity and Type 2 Diabetes. Nutrients 2021, 13, 758.

Berk KA, van der Louw EJTM, Olieman JF, van der Lely AJ · Nutrients · 2021-10-15

Preclinical / mechanistic

206. Ketogenic diet aggravates kidney dysfunction by exacerbating metabolic disorders and inhibiting autophagy in spontaneously hypertensive rats.

Jia P, Huang B, You Y, Su H, Gao L · Biochemical and biophysical research communications · 2021-08-03

Review

207. Measuring ketone bodies for the monitoring of pathologic and therapeutic ketosis.

Anderson JC, Mattar SG, Greenway FL, Lindquist RJ · Obesity science & practice · 2021-05-04

Review

208. Ketogenic diets in the management of type 1 diabetes: Safe or safety concern?

Buehler LA, Noe D, Knapp S, Isaacs D, Pantalone KM · Cleveland Clinic journal of medicine · 2021-10-01

Other

209. Nutritional ketosis is well-tolerated, even in type 1 diabetes: the ZeroFive100 Project; a proof-of-concept study.

Lake I · Current opinion in endocrinology, diabetes, and obesity · 2021-08-03

Other

210. Expanding Dietary Therapy Beyond the Classic Ketogenic Diet: On the Use of the Modified Atkins Diet and Low Glycemic Index Treatment in Pediatric Epilepsy.

Whitney R, Nair RR · Indian pediatrics · 2021-09-11

Case report / case series

211. The risk of ketogenic diets while breastfeeding: severe euglycaemic ketoacidosis.

Habashy NS, Tan H, Hibbert EJ · The Medical journal of Australia · 2021-08-11

Preclinical / mechanistic

212. Novel ketogenic diet formulation improves sucrose-induced insulin resistance in canton strain Drosophila melanogaster.

Kayode OT, Rotimi D, Okoh E, Iyobhebhe M, Kayode AAA, Ojo OA · Journal of food biochemistry · 2021-08-18

Clinical trial / intervention

213. Effects of low-carbohydrate diet and ketogenic diet on glucose and lipid metabolism in type 2 diabetic mice.

Yang Z, Mi J, Wang Y, Xue L, Liu J, Fan M, Zhang D, Wang L, Qian H, Li Y · Nutrition (Burbank, Los Angeles County, Calif.) · 2021-03-04

Review

214. Ketone Bodies in the Brain Beyond Fuel Metabolism: From Excitability to Gene Expression and Cell Signaling.

García-Rodríguez D, Giménez-Cassina A · Frontiers in molecular neuroscience · 2021-08-27

Clinical trial / intervention

215. Metabolic Derangement in Pediatric Patient with Obesity: The Role of Ketogenic Diet as Therapeutic Tool.

Calcaterra V, Verduci E, Pascuzzi MC, Magenes VC, Fiore G, Di Profio E, Tenuta E, Bosetti A, Todisco CF, D'Auria E, Zuccotti G · Nutrients · 2021-08-16

Preclinical / mechanistic

216. Slow but Steady-The Responsiveness of Sympathoadrenal System to a Hypoglycemic Challenge in Ketogenic Diet-Fed Rats.

Nedoboy PE, Cohen M, Farnham MM · Nutrients · 2021-07-29

Review

217. Ketogenic diet for depression: A potential dietary regimen to maintain euthymia?

Włodarczyk A, Cubała WJ, Stawicki M · Progress in neuro-psychopharmacology & biological psychiatry · 2021-01-23

Case report / case series

218. Treating Diabetes Utilizing a Low Carbohydrate Ketogenic Diet and Intermittent Fasting Without Significant Weight Loss: A Case Report.

Gavidia K, Kalayjian T · Frontiers in nutrition · 2021-06-28

Randomized clinical trial

219. Tolerability and Safety of a Novel Ketogenic Ester, Bis-Hexanoyl (R)-1,3-Butanediol: A Randomized Controlled Trial in Healthy Adults.

Chen O, Blonquist TM, Mah E, Sanoshy K, Beckman D, Nieman KM, Winters BL, Anthony JC, Verdin E, Newman JC, Stubbs BJ · Nutrients · 2021-06-16

Randomized clinical trial

220. Abdominal fat distribution modulates the metabolic effects of exogenous ketones in individuals with new-onset prediabetes after acute pancreatitis: Results from a randomized placebo-controlled trial.

Bharmal SH, Alarcon Ramos GC, Ko J, Petrov MS · Clinical nutrition ESPEN · 2021-03-21

Other

221. Pseudo-Reversal of Noninsulin-Treated Type 2 Diabetes on the Ketogenic Diet.

Abrahim M · Canadian journal of diabetes · 2020-10-01

Guideline / consensus

222. Medical management of children with type 1 diabetes on low-carbohydrate or ketogenic diets.

Rydin AA, Spiegel G, Frohnert BI, Kaess A, Oswald L, Owen D, Simmons KM · Pediatric diabetes · 2021-02-16

Randomized clinical trial

223. Ingestion of an exogenous ketone monoester improves the glycemic response during oral glucose tolerance test in individuals with impaired glucose tolerance: A cross-over randomized trial.

Nakagata T, Tamura Y, Kaga H, Sato M, Yamasaki N, Someya Y, Kadowaki S, Sugimoto D, Satoh H, Kawamori R, Watada H · Journal of diabetes investigation · 2020-11-01

Randomized clinical trial

224. Acute Nutritional Ketosis and Its Implications for Plasma Glucose and Glucoregulatory Peptides in Adults with Prediabetes: A Crossover Placebo-Controlled Randomized Trial.

Bharmal SH, Cho J, Alarcon Ramos GC, Ko J, Cameron-Smith D, Petrov MS · The Journal of nutrition · 2020-05-26

Review

225. Clinical Implications for Women of a Low-Carbohydrate or Ketogenic Diet With Intermittent Fasting.

Arbour MW, Stec M, Walker KC, Wika JC · Nursing for women's health · 2020-02-21

Preclinical / mechanistic

226. Ketogenic Diets Induced Glucose Intolerance and Lipid Accumulation in Mice with Alterations in Gut Microbiota and Metabolites.

Li Y, Yang X, Zhang J, Jiang T, Zhang Z, Wang Z, Gong M, Zhao L, Zhang C · mBio · 2021-03-30

Randomized clinical trial

227. Adherence to Ketogenic and Mediterranean Study Diets in a Crossover Trial: The Keto-Med Randomized Trial.

Landry MJ, Crimarco A, Perelman D, Durand LR, Petlura C, Aronica L, Robinson JL, Kim SH, Gardner CD · Nutrients · 2021-03-17

Clinical trial / intervention

228. Sex-specific effects of ketogenic diet after pre-exposure to a high-fat, high-sugar diet in rats.

Sahagun E, Bachman BB, Kinzig KP · Nutrition, metabolism, and cardiovascular diseases : NMCD · 2020-10-09

Other

229. Ketogenic Diet as a Normal Way of Eating in Adults With Type 1 and Type 2 Diabetes: A Qualitative Study.

Wong K, Raffray M, Roy-Fleming A, Blunden S, Brazeau AS · Canadian journal of diabetes · 2020-06-27

Observational human study

230. Very-Low-Calorie Ketogenic Diet as a Safe and Valuable Tool for Long-Term Glycemic Management in Patients with Obesity and Type 2 Diabetes.

Moriconi E, Camajani E, Fabbri A, Lenzi A, Caprio M · Nutrients · 2021-02-26

Case report / case series

231. Ketogenic Diet-Induced Diabetic Ketoacidosis in a Young Adult with Unrecognized Type 1 Diabetes.

Charoensri S, Sothornwit J, Trirattanapikul A, Pongchaiyakul C · Case reports in endocrinology · 2021-02-08

Randomized clinical trial

232. Impact of Acutely Increased Endogenous- and Exogenous Ketone Bodies on FGF21 Levels in Humans.

Lauritzen ES, Svart MV, Voss T, Møller N, Bjerre M · Endocrine research · 2020-10-19

Preclinical / mechanistic

233. Ingested Ketone Ester Leads to a Rapid Rise of Acetyl-CoA and Competes with Glucose Metabolism in the Brain of Non-Fasted Mice.

Suissa L, Kotchetkov P, Guigonis JM, Doche E, Osman O, Pourcher T, Lindenthal S · International journal of molecular sciences · 2021-01-07

Case report / case series

234. Euglycemic Diabetic Ketoacidosis Caused by SGLT2 Inhibitors and a Ketogenic Diet: A Case Series and Review of Literature.

Mistry S, Eschler DC · AACE clinical case reports · 2020-12-28

Clinical trial / intervention

235. Isocaloric Ketogenic Diet in Adults with High-Grade Gliomas: A Prospective Metabolic Study.

Foppiani A, De Amicis R, Lessa C, Leone A, Ravella S, Ciusani E, Silvani A, Zuccoli G, Battezzati A, Lamperti E, Bertoli S · Nutrition and cancer · 2020-06-17

Other

236. Severe ketoacidosis in a lactating woman on a ketogenic diet.

Alsomali M · Internal medicine journal · 2019-12-04

Case report / case series

237. Euglycemic Diabetic Ketoacidosis in a Patient Prescribed Empagliflozin and a Ketogenic Diet: A Case of Misdiagnosed Type 1 Diabetes.

Hendrickson AL, Ye XQ, Kalra SS, Franck AJ, Urbine D · Clinical diabetes : a publication of the American Diabetes Association · 2021-02-08

Randomized clinical trial

238. Effects of acute nutritional ketosis during exercise in adults with glycogen storage disease type IIIa are phenotype-specific: An investigator-initiated, randomized, crossover study.

Hoogeveen IJ, de Boer F, Boonstra WF, van der Schaaf CJ, Steuerwald U, Sibeijn-Kuiper AJ, Vegter RJK, van der Hoeven JH, Heiner-Fokkema MR, Clarke KC, Cox PJ, Derks TGJ, Jeneson JAL · Journal of inherited metabolic disease · 2020-09-07

Review

239. Implicating the effect of ketogenic diet as a preventive measure to obesity and diabetes mellitus.

Kumar S, Behl T, Sachdeva M, Sehgal A, Kumari S, Kumar A, Kaur G, Yadav HN, Bungau S · Life sciences · 2020-10-26

Other

240. Effectiveness of Ketogenic Diets on the Survival of Adult Oncological Patients.

Minzer S · Nutrition and cancer · 2020-10-19

Review

241. [Ketogenic diet – mechanism of action and perspectives for the use in the therapy: data from clinical studies].

Pondel N, Liśkiewicz D, Liśkiewicz A · Postepy biochemii · 2020-12-13

Other

242. The Islet De-stress Hypothesis: A potential explanation for the gluco metabolic effects of ketogenic diet.

Kalra S, Singla R, Dhawan M, Bhattacharya S, Aggarwal S · JPMA. The Journal of the Pakistan Medical Association · 2021-01-21

Review

243. Mechanisms of insulin resistance, mitochondrial dysfunction and the action of the ketogenic diet in bipolar disorder. Focus on the PI3K/AKT/HIF1-a pathway.

Campbell I, Campbell H · Medical hypotheses · 2020-09-24

Other

244. Stability of 0.5% Glucose-Containing Balanced Electrolyte Solutions for Patients on Ketogenic Diets: A Laboratory Study.

Heiderich S, Dennhardt N, Hartmann H, Kluger GJ, Sümpelmann R, Herberhold T · Neuropediatrics · 2020-08-25

Review

245. Emerging Therapeutic Promise of Ketogenic Diet to Attenuate Neuropathological Alterations in Alzheimer's Disease.

Uddin MS, Kabir MT, Tewari D, Al Mamun A, Barreto GE, Bungau SG, Bin-Jumah MN, Abdel-Daim MM, Ashraf GM · Molecular neurobiology · 2020-08-20

Systematic review / meta-analysis

246. Effect of the ketogenic diet on glycemic control, insulin resistance, and lipid metabolism in patients with T2DM: a systematic review and meta-analysis.

Yuan X, Wang J, Yang S, Gao M, Cao L, Li X, Hong D, Tian S, Sun C · Nutrition & diabetes · 2020-11-30

Review

247. The dark side of the spoon - glucose, ketones and COVID-19: a possible role for ketogenic diet?

Paoli A, Gorini S, Caprio M · Journal of translational medicine · 2020-11-20

Preclinical / mechanistic

248. High-Intensity Interval Training Attenuates Ketogenic Diet-Induced Liver Fibrosis in Type 2 Diabetic Mice by Ameliorating TGF-β1/Smad Signaling.

Zhang Q, Shen F, Shen W, Xia J, Wang J, Zhao Y, Zhang Z, Sun Y, Qian M, Ding S · Diabetes, metabolic syndrome and obesity : targets and therapy · 2020-11-06

Observational human study

249. [Clinical characteristics and ketogenic diet therapy of glucose transporter type 1 deficiency syndrome in children: a multicenter clinical study].

Yu LF, Zhang YQ, Duan J, Ni Y, Gong XY, Lu ZY, Liao JX, Lu XP, Shi ZN, Lei MF, Zhong JM, Zha J, Zhou SZ · Zhonghua er ke za zhi = Chinese journal of pediatrics · 2020-10-29

Case report / case series

250. SUCCESSFUL REIMPLEMENTATION OF A VERY LOW CARBOHYDRATE KETOGENIC DIET AFTER SGLT2 INHIBITOR ASSOCIATED EUGLYCEMIC DIABETIC KETOACIDOSIS.

Fieger EI, Fadel KM, Modarres AH, Wickham EP, Wolver SE · AACE clinical case reports · 2020-08-06

Observational human study

251. Longitudinal changes in insulin resistance in children with epilepsy on ketogenic diet: Prevalence and risk factors.

Kong J, Nam SO, Ko A, Byun SY, Lim TJ, Kim YM, Yeon GM, Cho JW, Lee YJ · Epilepsy & behavior : E&B · 2020-08-22

Preclinical / mechanistic

252. G6PC2 confers protection against hypoglycemia upon ketogenic diet feeding and prolonged fasting.

Bosma KJ, Rahim M, Oeser JK, McGuinness OP, Young JD, O'Brien RM · Molecular metabolism · 2020-06-20

Systematic review / meta-analysis

253. Effects of the Ketogenic Diet on Glycemic Control in Diabetic Patients: Meta-Analysis of Clinical Trials.

Alarim RA, Alasmre FA, Alotaibi HA, Alshehri MA, Hussain SA · Cureus · 2020-10-05

Case report / case series

254. Incorporation of the Ketogenic Diet in a Youth With Type 1 Diabetes.

Cogen FR · Clinical diabetes : a publication of the American Diabetes Association · 2020-11-02

Other

255. Ketonemia and Glycemia Affect Appetite Levels and Executive Functions in Overweight Females During Two Ketogenic Diets.

Lodi A, Zarantonello L, Bisiacchi PS, Cenci L, Paoli A · Obesity (Silver Spring, Md.) · 2020-09-01

Review

256. The biochemistry of low-carbohydrate and ketogenic diets.

Feinman RD · Current opinion in endocrinology, diabetes, and obesity · 2020-08-17

Preclinical / mechanistic

257. The Effect of Exogenous Ketone Monoester Ingestion on Plasma BDNF During an Oral Glucose Tolerance Test.

Walsh JJ, Myette-Côté É, Little JP · Frontiers in physiology · 2020-09-09

Other

258. [VLCD and VLCKD in the treatment of obese people with non-insulin-dependent diabetes or prediabetes: clinical evidence and reflections.].

Fatati G · Recenti progressi in medicina · 2020-09-11

Clinical trial / intervention

259. Ketogenic diets as treatment of obesity and type 2 diabetes mellitus.

Casanueva FF, Castellana M, Bellido D, Trimboli P, Castro AI, Sajoux I, Rodriguez-Carnero G, Gomez-Arbelaez D, Crujeiras AB, Martinez-Olmos MA · Reviews in endocrine & metabolic disorders · 2020-08-18

Preclinical / mechanistic

260. MRI spectroscopic and tractography studies indicate consequences of long-term ketogenic diet.

Gzieło K, Janeczko K, Węglarz W, Jasiński K, Kłodowski K, Setkowicz Z · Brain structure & function · 2020-07-17

Randomized clinical trial

261. [Inhibitory effect of ketogenic diet on neuroblastoma in BALB/c-nu mouse models].

He J, Lü L, Peng J, Li C, Kong X, Zhang J, Peng L · Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2020-09-08

Case report / case series

262. A case report of glucose transporter 1 deficiency syndrome with growth hormone deficiency diagnosed before starting ketogenic diet.

Tornese G, Patti G, Pellegrin MC, Costa P, Faletra F, Faleschini E, Barbi E · Italian journal of pediatrics · 2020-08-26

Clinical trial / intervention

263. A Case of Diabetic Ketoacidosis in a Patient on an SGLT2 Inhibitor and a Ketogenic Diet: A Critical Trio Not to Be Missed.

Steinmetz-Wood S, Gilbert M, Menson K · Case reports in endocrinology · 2020-08-13

Case report / case series

264. [Euglycaemic ketoacidosis induced by ketogenic diet and intermittent fastingin a non-diabetic patient].

Mellbye FB, Pedersen MGB · Ugeskrift for laeger · 2020-08-01

Case report / case series

265. Therapeutic use of intermittent fasting and ketogenic diet as an alternative treatment for type 2 diabetes in a normal weight woman: a 14-month case study.

Lichtash C, Fung J, Ostoich KC, Ramos M · BMJ case reports · 2020-07-07

Systematic review / meta-analysis

266. Impact of a Ketogenic Diet on Metabolic Parameters in Patients with Obesity or Overweight and with or without Type 2 Diabetes: A Meta-Analysis of Randomized Controlled Trials.

Choi YJ, Jeon SM, Shin S · Nutrients · 2020-07-06

Case report / case series

267. Ketogenic Diet as a Trigger for Diabetic Ketoacidosis in a Misdiagnosis of Diabetes: A Case Report.

White-Cotsmire AJ, Healy AM · Clinical diabetes : a publication of the American Diabetes Association · 2020-07-24

Other

268. An overlooked danger of ketogenic diets: Making the case that ketone bodies induce vascular damage by the same mechanisms as glucose.

Burkitt MJ · Nutrition (Burbank, Los Angeles County, Calif.) · 2020-02-14

Case report / case series

269. Ketoacidosis associated with ketogenic diet in a non-diabetic lactating woman.

Alkhayat A, Arao K, Minami T, Manzoor K · BMJ case reports · 2020-06-30

Randomized clinical trial

270. The Effects of a Low Calorie Ketogenic Diet on Glycaemic Control Variables in Hyperinsulinemic Overweight/Obese Females.

Michalczyk MM, Klonek G, Maszczyk A, Zajac A · Nutrients · 2020-06-22

Clinical trial / intervention

271. The Ketogenic Diet: Evidence for Optimism but High-Quality Research Needed.

Ludwig DS · The Journal of nutrition · 2019-09-23

Clinical trial / intervention

272. Exploring the Feasibility and Effects of a Ketogenic Diet in Patients With CNS Malignancies: A Retrospective Case Series.

Panhans CM, Gresham G, Amaral LJ, Hu J · Frontiers in neuroscience · 2020-05-19

Preclinical / mechanistic

273. Consuming a ketogenic diet leads to altered hypoglycemic counter-regulation in mice.

Morrison CD, Hill CM, DuVall MA, Coulter CE, Gosey JL, Herrera MJ, Maisano LE, Sikaffy HX, McDougal DH · Journal of diabetes and its complications · 2020-02-08

Case report / case series

274. Very restricted carbohydrate (ketogenic) diet: A rare cause of a recurrent hypoglycemic-euglycemic diabetic ketoacidosis in the pregnancy.

Yaron M, Shalit R, Kreiser D, Cukierman-Yaffe T, Yoeli R · European journal of obstetrics, gynecology, and reproductive biology · 2020-03-07

Clinical trial / intervention

275. The 'epileptic diet'- ketogenic and/or slow release of glucose intervention: A review.

Qi X, Tester RF · Clinical nutrition (Edinburgh, Scotland) · 2019-06-08

Systematic review / meta-analysis

276. Are ketogenic diets promising for Alzheimer's disease? A translational review.

Lilamand M, Porte B, Cognat E, Hugon J, Mouton-Liger F, Paquet C · Alzheimer's research & therapy · 2020-04-14

Case report / case series

277. A Case of Euglycemic Diabetic Ketoacidosis Triggered by a Ketogenic Diet in a Patient With Type 2 Diabetes Using a Sodium-Glucose Cotransporter 2 Inhibitor.

Garay PS, Zuniga G, Lichtenberg R · Clinical diabetes : a publication of the American Diabetes Association · 2020-04-25

Case report / case series

278. Usefulness of Continuous Glucose Monitoring for Prevention and Early Detection of Hypoglycemia Caused by a Ketogenic Diet and Late Dumping Syndrome.

Morikawa M, Hara Y, Nakazawa Y, Inaba Y, Motobayashi M · Pediatric neurology · 2019-12-26

Review

279. Modulation of Cellular Biochemistry, Epigenetics and Metabolomics by Ketone Bodies. Implications of the Ketogenic Diet in the Physiology of the Organism and Pathological States.

Dąbek A, Wojtala M, Pirola L, Balcerczyk A · Nutrients · 2020-03-17

Other

280. Consumer Reports of "Keto Flu" Associated With the Ketogenic Diet.

Bostock ECS, Kirkby KC, Taylor BV, Hawrelak JA · Frontiers in nutrition · 2020-03-13

Review

281. Glucose transporter type 1 deficiency syndrome and the ketogenic diet.

Schwantje M, Verhagen LM, van Hasselt PM, Fuchs SA · Journal of inherited metabolic disease · 2019-11-13

Case report / case series

282. Attenuation of Hemolysis Due to Glucose-6-Phosphate Isomerase Deficiency With Ketogenic Diet - A Case Report.

Park H, Haller J, Smith F, Parkin N, Lythe T, Zoeller RA, Chakravorty S · HemaSphere · 2020-01-03

Case report / case series

283. Accuracy of Flash Glucose Monitoring in a Patient with Dravet Syndrome on a Ketogenic Diet.

Kortas A, Schiller K, Unterholzner G, Rauchenzauner M · Neuropediatrics · 2019-09-17

Clinical trial / intervention

284. Nutritional ketosis as an intervention to relieve astrogliosis: Possible therapeutic applications in the treatment of neurodegenerative and neuroprogressive disorders.

Morris G, Maes M, Berk M, Carvalho AF, Puri BK · European psychiatry : the journal of the Association of European Psychiatrists · 2020-01-31

Other

286. Beneficial Effects of Modified Atkins Diet in Glycogen Storage Disease Type IIIa.

Olgac A, İnci A, Okur İ, Biberoğlu G, Oğuz D, Ezgü FS, Kasapkara ÇS, Aktaş E, Tümer L · Annals of nutrition & metabolism · 2020-07-24

Review

287. Potential Therapeutic Effects of Exogenous Ketone Supplementation for Type 2 Diabetes: A Review.

Walsh JJ, Myette-Côté É, Neudorf H, Little JP · Current pharmaceutical design · 2019-08-19

Case report / case series

288. Euglycaemic ketoacidosis from an SGLT2 inhibitor exacerbated by a ketogenic diet.

Sinha S, Gavaghan D, Yew S · The Medical journal of Australia · 2019-12-01

Case report / case series

289. [Ketogenic diet as a trigger for diabetic euglycaemic ketoacidosis in a patient under treatment with iSGLT2].

Nubiola A, Ternianov A, Remolins I · Hipertension y riesgo vascular · 2019-11-14

Preclinical / mechanistic

290. Liver-derived FGF21 is essential for full adaptation to ketogenic diet but does not regulate glucose homeostasis.

Watanabe M, Singhal G, Fisher FM, Beck TC, Morgan DA, Socciarelli F, Mather ML, Risi R, Bourke J, Rahmouni K, McGuinness OP, Flier JS, Maratos-Flier E · Endocrine · 2019-11-14

Other

291. Ketogenic Diets in Critical Care?

Bistrian BR · JPEN. Journal of parenteral and enteral nutrition · 2019-06-27

Other

292. Ketogenic Diets for Diabetes and Obesity-Reply.

Joshi S, Ostfeld RJ, McMacken M · JAMA internal medicine · 2019-12-03

Other

293. Ketogenic Diet for Obesity and Diabetes.

Yancy WS, Mitchell NS, Westman EC · JAMA internal medicine · 2019-12-03

Other

294. Ketogenic Diets for Diabetes and Obesity.

Hecht FM · JAMA internal medicine · 2019-12-03

Clinical trial / intervention

295. Ketogenic Diet: an Endocrinologist Perspective.

Kuchkuntla AR, Shah M, Velapati S, Gershuni VM, Rajjo T, Nanda S, Hurt RT, Mundi MS · Current nutrition reports · 2019-11-11

Case report / case series

296. Starvation Ketoacidosis due to the Ketogenic Diet and Prolonged Fasting - A Possibly Dangerous Diet Trend.

Blanco JC, Khatri A, Kifayat A, Cho R, Aronow WS · The American journal of case reports · 2019-11-22

Clinical trial / intervention

297. Lessons learned from recent clinical trials of ketogenic diet therapies in adults.

McDonald TJW, Cervenka MC · Current opinion in clinical nutrition and metabolic care · 2019-09-11

Case report / case series

298. Glycaemic stability of a cyclist with Type 1 diabetes: 4011 km in 20 days on a ketogenic diet.

Nolan J, Rush A, Kaye J · Diabetic medicine : a journal of the British Diabetic Association · 2019-07-04

Preclinical / mechanistic

299. Ketogenic diet compromises vertebral microstructure and biomechanical characteristics in mice.

Wu X, Ding J, Xu X, Wang X, Liu J, Jiang J, Liu Q, Kong G, Huang Z, Yang Z, Zhu Q · Journal of bone and mineral metabolism · 2019-04-09

Review

300. The management of very low-calorie ketogenic diet in obesity outpatient clinic: a practical guide.

Muscogiuri G, Barrea L, Laudisio D, Pugliese G, Salzano C, Savastano S, Colao A · Journal of translational medicine · 2019-10-29

Preclinical / mechanistic

301. Exogenous Ketones Lower Blood Glucose Level in Rested and Exercised Rodent Models.

Ari C, Murdun C, Koutnik AP, Goldhagen CR, Rogers C, Park C, Bharwani S, Diamond DM, Kindy MS, D'Agostino DP, Kovács Z · Nutrients · 2019-10-01

Preclinical / mechanistic

302. The mystery of the ketogenic diet: benevolent pseudo-diabetes.

Blagosklonny MV · Cell cycle (Georgetown, Tex.) · 2019-08-01

Clinical trial / intervention

303. Improvement in Glycemic and Lipid Profiles in Type 2 Diabetics with a 90-Day Ketogenic Diet.

Walton CM, Perry K, Hart RH, Berry SL, Bikman BT · Journal of diabetes research · 2019-08-14

Other

304. Effects of a Personalized VLCKD on Body Composition and Resting Energy Expenditure in the Reversal of Diabetes to Prevent Complications.

Romano L, Marchetti M, Gualtieri P, Di Renzo L, Belcastro M, De Santis GL, Perrone MA, De Lorenzo A · Nutrients · 2019-07-04

Randomized clinical trial

305. Long-Term Effects of a Novel Continuous Remote Care Intervention Including Nutritional Ketosis for the Management of Type 2 Diabetes: A 2-Year Non-randomized Clinical Trial.

Athinarayanan SJ, Adams RN, Hallberg SJ, McKenzie AL, Bhanpuri NH, Campbell WW, Volek JS, Phinney SD, McCarter JP · Frontiers in endocrinology · 2019-06-05

Review

306. [Ketogenic Diet and its Evidence-Based Therapeutic Implementation in Endocrine Diseases].

Stocker RK, Reber Aubry E, Bally L, Nuoffer JM, Stanga Z · Praxis · 2019-06-13

Other

307. Glucose and Lipid Homeostasis and Inflammation in Humans Following an Isocaloric Ketogenic Diet.

Rosenbaum M, Hall KD, Guo J, Ravussin E, Mayer LS, Reitman ML, Smith SR, Walsh BT, Leibel RL · Obesity (Silver Spring, Md.) · 2019-05-08

Other

308. Can a ketogenic diet be safely used to improve glycaemic control in a child with type 1 diabetes?

McClean AM, Montorio L, McLaughlin D, McGovern S, Flanagan N · Archives of disease in childhood · 2018-11-23

Clinical trial / intervention

309. Low-Carb and Ketogenic Diets in Type 1 and Type 2 Diabetes.

Bolla AM, Caretto A, Laurenzi A, Scavini M, Piemonti L · Nutrients · 2019-04-26

Other

310. Pre ketogenic diet counselling.

Kalra S, Singla R, Rosha R, Sharma S, Surana V, Kalra B · JPMA. The Journal of the Pakistan Medical Association · 2019-04-20

Case report / case series

311. The challenges in managing perioperative hypoglycemia in a child on modified Atkins diet.

Mak W, Xu K, Lim SW, Hee HI · Paediatric anaesthesia · 2019-02-06

Review

312. Optimizing glycemic control in type 2 diabetic patients through the use of a low-carbohydrate, high-fat, ketogenic diet: a review of two patients in primary care.

Rallis S · Diabetes, metabolic syndrome and obesity : targets and therapy · 2019-03-05

Clinical trial / intervention

313. Ketogenic diets potentially reverse Type II diabetes and ameliorate clinical depression: A case study.

Cox N, Gibas S, Salisbury M, Gomer J, Gibas K · Diabetes & metabolic syndrome · 2019-02-06

Randomized clinical trial

314. Improvement in patient-reported sleep in type 2 diabetes and prediabetes participants receiving a continuous care intervention with nutritional ketosis.

Siegmann MJ, Athinarayanan SJ, Hallberg SJ, McKenzie AL, Bhanpuri NH, Campbell WW, McCarter JP, Phinney SD, Volek JS, Van Dort CJ · Sleep medicine · 2019-01-03

Clinical trial / intervention

315. Ketogenic diet: situational analysis of current nutrition guidelines.

Kalra S, Singla R, Rosha R, Dhawan M · JPMA. The Journal of the Pakistan Medical Association · 2018-12-04

Review

316. Ketogenic diet versus ketoacidosis: what determines the influence of ketone bodies on neurons?

Fedorovich SV, Voronina PP, Waseem TV · Neural regeneration research · 2018-10-17

Preclinical / mechanistic

317. Short-term feeding of a ketogenic diet induces more severe hepatic insulin resistance than an obesogenic high-fat diet.

Grandl G, Straub L, Rudigier C, Arnold M, Wueest S, Konrad D, Wolfrum C · The Journal of physiology · 2018-08-08

Review

318. Implementing a low-carbohydrate, ketogenic diet to manage type 2 diabetes mellitus.

Westman EC, Tondt J, Maguire E, Yancy WS · Expert review of endocrinology & metabolism · 2018-10-06

Review

319. Nutritional Ketosis for Weight Management and Reversal of Metabolic Syndrome.

Gershuni VM, Yan SL, Medici V · Current nutrition reports · 2018-08-22

Clinical trial / intervention

320. Reduced mitochondrial reactive oxygen species production in peripheral nerves of mice fed a ketogenic diet.

Cooper MA, McCoin C, Pei D, Thyfault JP, Koestler D, Wright DE · Experimental physiology · 2018-08-08

Preclinical / mechanistic

321. Rescue of 2-Deoxyglucose Side Effects by Ketogenic Diet.

Voss M, Lorenz NI, Luger AL, Steinbach JP, Rieger J, Ronellenfitsch MW · International journal of molecular sciences · 2018-08-20

Case report / case series

322. Successful treatment of obesity and insulin resistance via ketogenic diet status post Roux-en-Y.

Handley RT, Bentley RE, Brown TL, Annan AA · BMJ case reports · 2018-08-17

Randomized clinical trial

323. Low-fat versus ketogenic diet in Parkinson's disease: A pilot randomized controlled trial.

Phillips MCL, Murtagh DKJ, Gilbertson LJ, Asztely FJS, Lynch CDP · Movement disorders : official journal of the Movement Disorder Society · 2018-08-11

Clinical trial / intervention

324. A ketogenic diet reduces metabolic syndrome-induced allodynia and promotes peripheral nerve growth in mice.

Cooper MA, Menta BW, Perez-Sanchez C, Jack MM, Khan ZW, Ryals JM, Winter M, Wright DE · Experimental neurology · 2018-05-17

Clinical trial / intervention

325. Therapeutic augmentation of ketogenic diet with a sodium-glucose cotransporter 2 inhibitor in a super-refractory status epilepticus patient.

Blunck JR, Newman JW, Fields RK, Croom JE · Epilepsy & behavior case reports · 2018-06-20

Other

326. The glycaemic benefits of a very-low-carbohydrate ketogenic diet in adults with Type 1 diabetes mellitus may be opposed by increased hypoglycaemia risk and dyslipidaemia.

Leow ZZX, Guelfi KJ, Davis EA, Jones TW, Fournier PA · Diabetic medicine : a journal of the British Diabetic Association · 2018-05-08

Randomized clinical trial

327. Authors' Reply: Comment on "An Online Intervention Comparing a Very Low-Carbohydrate Ketogenic Diet and Lifestyle Recommendations Versus a Plate Method Diet in Overweight Individuals With Type 2 Diabetes: A Randomized Controlled Trial".

Saslow L, Mason AE, Kim S, Goldman V, Ploutz-Snyder R, Bayandorian H, Daubenmier J, Hecht FM, Moskowitz JT · Journal of medical Internet research · 2018-05-01

Randomized clinical trial

328. Cardiovascular disease risk factor responses to a type 2 diabetes care model including nutritional ketosis induced by sustained carbohydrate restriction at 1 year: an open label, non-randomized, controlled study.

Bhanpuri NH, Hallberg SJ, Williams PT, McKenzie AL, Ballard KD, Campbell WW, McCarter JP, Phinney SD, Volek JS · Cardiovascular diabetology · 2018-05-01

Other

329. Questionnaire survey on the current status of ketogenic diet therapy in patients with glucose transporter 1 deficiency syndrome (GLUT1DS) in Japan.

Oguni H, Ito Y, Otani Y, Nagata S · European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society · 2017-12-26

Other

330. The glucose-lowering effects of exogenous ketones: is there therapeutic potential?

Egan B · The Journal of physiology · 2018-03-24

Randomized clinical trial

331. Prior ingestion of exogenous ketone monoester attenuates the glycaemic response to an oral glucose tolerance test in healthy young individuals.

Myette-Côté É, Neudorf H, Rafiei H, Clarke K, Little JP · The Journal of physiology · 2018-03-02

Clinical trial / intervention

332. Treatment of Diabetic Mice with a Combination of Ketogenic Diet and Aerobic Exercise via Modulations of PPARs Gene Programs.

Zhang Q, Xu L, Xia J, Wang D, Qian M, Ding S · PPAR research · 2018-03-20

Review

333. [The effects of ketogenic diet are numerous].

Møhl T, Miranda MJ · Ugeskrift for laeger · 2018-03-15

Preclinical / mechanistic

334. The modification of the ketogenic diet mitigates its stunting effects in rodents.

Liśkiewicz AD, Kasprowska-Liśkiewicz D, Sługocka A, Nowacka-Chmielewska MM, Wiaderkiewicz J, Jędrzejowska-Szypułka H, Barski JJ, Lewin-Kowalik J · Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme · 2017-10-18

Other

335. Interest in the Ketogenic Diet Grows for Weight Loss and Type 2 Diabetes.

Abbasi J · JAMA · 2018-01-18

Review

336. Ketogenic diet in endocrine disorders: Current perspectives.

Gupta L, Khandelwal D, Kalra S, Gupta P, Dutta D, Aggarwal S · Journal of postgraduate medicine · 2017-10-13

Clinical trial / intervention

337. Acid-base safety during the course of a very low-calorie-ketogenic diet.

Gomez-Arbelaez D, Crujeiras AB, Castro AI, Goday A, Mas-Lorenzo A, Bellon A, Tejera C, Bellido D, Galban C, Sajoux I, Lopez-Jaramillo P, Casanueva FF · Endocrine · 2017-09-15

Review

338. Dietary guidelines in type 2 diabetes: the Nordic diet or the ketogenic diet?

Magnusdottir OK, Gunnarsdottir I, Birgisdóttir BE · Current opinion in endocrinology, diabetes, and obesity · 2017-07-21

Preclinical / mechanistic

339. The ketogenic diet affects the social behavior of young male rats.

Kasprowska-Liśkiewicz D, Liśkiewicz AD, Nowacka-Chmielewska MM, Nowicka J, Małecki A, Barski JJ · Physiology & behavior · 2017-06-13

Preclinical / mechanistic

340. Synergistic protection against acute flurothyl-induced seizures by adjuvant treatment of the ketogenic diet with the type 2 diabetes drug pioglitazone.

Simeone TA, Matthews SA, Simeone KA · Epilepsia · 2017-05-28

Preclinical / mechanistic

341. Sex-Specific Life Course Changes in the Neuro-Metabolic Phenotype of Glut3 Null Heterozygous Mice: Ketogenic Diet Ameliorates Electroencephalographic Seizures and Improves Sociability.

Dai Y, Zhao Y, Tomi M, Shin BC, Thamotharan S, Mazarati A, Sankar R, Wang EA, Cepeda C, Levine MS, Zhang J, Frew A, Alger JR, Clark PM, Sondhi M, Kositamongkol S, Leibovitch L, Devaskar SU · Endocrinology · 2016-11-03

Randomized clinical trial

342. An Online Intervention Comparing a Very Low-Carbohydrate Ketogenic Diet and Lifestyle Recommendations Versus a Plate Method Diet in Overweight Individuals With Type 2 Diabetes: A Randomized Controlled Trial.

Saslow LR, Mason AE, Kim S, Goldman V, Ploutz-Snyder R, Bayandorian H, Daubenmier J, Hecht FM, Moskowitz JT · Journal of medical Internet research · 2017-02-13

Preclinical / mechanistic

343. Streptozotocin diabetes increases mRNA expression of ketogenic enzymes in the rat heart.

Cook GA, Lavrentyev EN, Pham K, Park EA · Biochimica et biophysica acta. General subjects · 2016-11-11

Other

344. Alternative ketogenic diets in glucose transporter type 1 deficiency syndrome.

De Laet C · Developmental medicine and child neurology · 2016-07-22

Observational human study

345. Use of modified Atkins diet in glucose transporter type 1 deficiency syndrome.

Amalou S, Gras D, Ilea A, Greneche MO, Francois L, Bellavoine V, Delanoe C, Auvin S · Developmental medicine and child neurology · 2016-06-08

Preclinical / mechanistic

346. Targeting of astrocytic glucose metabolism by beta-hydroxybutyrate.

Valdebenito R, Ruminot I, Garrido-Gerter P, Fernández-Moncada I, Forero-Quintero L, Alegría K, Becker HM, Deitmer JW, Barros LF · Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2015-10-29

Randomized clinical trial

347. Short-term safety, tolerability and efficacy of a very low-calorie-ketogenic diet interventional weight loss program versus hypocaloric diet in patients with type 2 diabetes mellitus.

Goday A, Bellido D, Sajoux I, Crujeiras AB, Burguera B, García-Luna PP, Oleaga A, Moreno B, Casanueva FF · Nutrition & diabetes · 2016-09-19

Preclinical / mechanistic

348. Ketogenic diet prevents neuronal firing increase within the substantia nigra during pentylenetetrazole-induced seizure in rats.

Viggiano A, Stoddard M, Pisano S, Operto FF, Iovane V, Monda M, Coppola G · Brain research bulletin · 2016-07-02

Randomized clinical trial

349. Eucaloric Ketogenic Diet Reduces Hypoglycemia and Inflammation in Mice with Endotoxemia.

Nandivada P, Fell GL, Pan AH, Nose V, Ling PR, Bistrian BR, Puder M · Lipids · 2016-04-27

Preclinical / mechanistic

350. Embryonic Lethality of Mitochondrial Pyruvate Carrier 1 Deficient Mouse Can Be Rescued by a Ketogenic Diet.

Vanderperre B, Herzig S, Krznar P, Hörl M, Ammar Z, Montessuit S, Pierredon S, Zamboni N, Martinou JC · PLoS genetics · 2016-05-13

Review

351. Ketogenic Diet and Cancer-a Perspective.

Smyl C · Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer · 2016-08-26

Preclinical / mechanistic

352. Ketogenic diet delays the phase of circadian rhythms and does not affect AMP-activated protein kinase (AMPK) in mouse liver.

Genzer Y, Dadon M, Burg C, Chapnik N, Froy O · Molecular and cellular endocrinology · 2015-09-25

Other

353. Low carbohydrate and ketogenic diets in type 2 diabetes.

Clifton P, Carter S, Headland M, Keogh J · Current opinion in lipidology · 2016-01-19

Other

354. Ketogenic diet reverses behavioral abnormalities in an acute NMDA receptor hypofunction model of schizophrenia.

Kraeuter AK, Loxton H, Lima BC, Rudd D, Sarnyai Z · Schizophrenia research · 2015-11-04

Observational human study

355. Middle and Long-Term Impact of a Very Low-Carbohydrate Ketogenic Diet on Cardiometabolic Factors: A Multi-Center, Cross-Sectional, Clinical Study.

Cicero AF, Benelli M, Brancaleoni M, Dainelli G, Merlini D, Negri R · High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2015-05-19

Preclinical / mechanistic

356. Ketogenic diet does not impair spatial ability controlled by the hippocampus in male rats.

Fukushima A, Ogura Y, Furuta M, Kakehashi C, Funabashi T, Akema T · Brain research · 2015-06-23

Other

357. Ketogenic response to cotreatment with bezafibrate and medium chain triacylglycerols in healthy humans.

Courchesne-Loyer A, St-Pierre V, Hennebelle M, Castellano CA, Fortier M, Tessier D, Cunnane SC · Nutrition (Burbank, Los Angeles County, Calif.) · 2015-06-06

Other

358. The Effects of Ketogenic Diet on Seizures, Cognitive Functions, and Other Neurological Disorders in Classical Phenotype of Glucose Transporter 1 Deficiency Syndrome.

Gumus H, Bayram AK, Kardas F, Canpolat M, Çağlayan AO, Kumandas S, Kendirci M, Per H · Neuropediatrics · 2015-08-12

Preclinical / mechanistic

359. FGF21 is not required for glucose homeostasis, ketosis or tumour suppression associated with ketogenic diets in mice.

Stemmer K, Zani F, Habegger KM, Neff C, Kotzbeck P, Bauer M, Yalamanchilli S, Azad A, Lehti M, Martins PJ, Müller TD, Pfluger PT, Seeley RJ · Diabetologia · 2015-06-23

Case report / case series

360. Ketogenic diet in a patient with congenital hyperinsulinism: a novel approach to prevent brain damage.

Maiorana A, Manganozzi L, Barbetti F, Bernabei S, Gallo G, Cusmai R, Caviglia S, Dionisi-Vici C · Orphanet journal of rare diseases · 2015-09-24

Preclinical / mechanistic

361. Ketone bodies effectively compete with glucose for neuronal acetyl-CoA generation in rat hippocampal slices.

Valente-Silva P, Lemos C, Köfalvi A, Cunha RA, Jones JG · NMR in biomedicine · 2015-07-15

Preclinical / mechanistic

362. The influence of the ketogenic diet on the elemental and biochemical compositions of the hippocampal formation.

Chwiej J, Skoczen A, Matusiak K, Janeczko K, Patulska A, Sandt C, Simon R, Ciarach M, Setkowicz Z · Epilepsy & behavior : E&B · 2015-05-16

Other

363. Short-term effects of ketogenic diet on anthropometric parameters, body fat distribution, and inflammatory cytokine production in GLUT1 deficiency syndrome.

Bertoli S, Neri IG, Trentani C, Ferraris C, De Amicis R, Battezzati A, Veggiotti P, De Giorgis V, Tagliabue A · Nutrition (Burbank, Los Angeles County, Calif.) · 2015-03-31

Review

364. The Ketogenic Diet and Sport: A Possible Marriage?

Paoli A, Bianco A, Grimaldi KA · Exercise and sport sciences reviews · 2015-04-24

Review

365. Mitochondria: The ketogenic diet--A metabolism-based therapy.

Vidali S, Aminzadeh S, Lambert B, Rutherford T, Sperl W, Kofler B, Feichtinger RG · The international journal of biochemistry & cell biology · 2015-02-07

Preclinical / mechanistic

366. Ketone bodies attenuate excitotoxic cell injury in the rat hippocampal slice under conditions of reduced glucose availability.

Youssef FF · Neurological research · 2014-08-01

Other

367. [Experience of using ketogenic diet in a patient with glucose transporter 1 deficiency syndrome (a case report)].

Lukyanova EG, Ayvazyan SO, Osipova KV, Pyreva EA, Sorvacheva TN · Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova · 2015-09-11

Clinical trial / intervention

368. Glycogen storage disease type III: modified Atkins diet improves myopathy.

Mayorandan S, Meyer U, Hartmann H, Das AM · Orphanet journal of rare diseases · 2014-11-28

Preclinical / mechanistic

369. Ketogenic diet sensitizes glucose control of hippocampal excitability.

Kawamura M, Ruskin DN, Geiger JD, Boison D, Masino SA · Journal of lipid research · 2014-08-28

Preclinical / mechanistic

370. Glucose reduces the anticonvulsant effects of the ketogenic diet in EL mice.

Mantis JG, Meidenbauer JJ, Zimick NC, Centeno NA, Seyfried TN · Epilepsy research · 2014-06-02

Case report / case series

371. Symptomatic west syndrome secondary to glucose transporter-1(GLUT1) deficiency with complete response to 4:1 ketogenic diet.

Vykuntaraju KN, Bhat S, Sanjay KS, Govindaraju M · Indian journal of pediatrics · 2013-04-19

Case report / case series

372. The ketogenic diet for the treatment of myoclonic astatic epilepsy in a child with type 1 diabetes mellitus.

Aylward NM, Shah N, Sellers EA · Canadian journal of diabetes · 2014-07-09

Case report / case series

373. Alternating hemiplegia of childhood with a de novo mutation in ATP1A3 and changes in SLC2A1 responsive to a ketogenic diet.

Ulate-Campos A, Fons C, Artuch R, Castejón E, Martorell L, Ozelius L, Pascual J, Campistol J · Pediatric neurology · 2013-12-04

Case report / case series

374. Glucose transporter type 1 deficiency syndrome effectively treated with modified Atkins diet.

Haberlandt E, Karall D, Jud V, Baumgartner SS, Zotter S, Rostasy K, Baumann M, Scholl-Buergi S · Neuropediatrics · 2013-07-25

Preclinical / mechanistic

375. Long-term ketogenic diet causes glucose intolerance and reduced β- and α-cell mass but no weight loss in mice.

Ellenbroek JH, van Dijck L, Töns HA, Rabelink TJ, Carlotti F, Ballieux BE, de Koning EJ · American journal of physiology. Endocrinology and metabolism · 2014-01-07

Case report / case series

376. Reversible white matter lesions during ketogenic diet therapy in glucose transporter 1 deficiency syndrome.

Shiohama T, Fujii K, Takahashi S, Nakamura F, Kohno Y · Pediatric neurology · 2013-09-27

Preclinical / mechanistic

377. Early decline in glucose transport and metabolism precedes shift to ketogenic system in female aging and Alzheimer's mouse brain: implication for bioenergetic intervention.

Ding F, Yao J, Rettberg JR, Chen S, Brinton RD · PloS one · 2013-11-11

Preclinical / mechanistic

378. Ketogenic diet improves forelimb motor function after spinal cord injury in rodents.

Streijger F, Plunet WT, Lee JH, Liu J, Lam CK, Park S, Hilton BJ, Fransen BL, Matheson KA, Assinck P, Kwon BK, Tetzlaff W · PloS one · 2013-11-04

Preclinical / mechanistic

379. A gestational ketogenic diet alters maternal metabolic status as well as offspring physiological growth and brain structure in the neonatal mouse.

Sussman D, Ellegood J, Henkelman M · BMC pregnancy and childbirth · 2013-10-29

Preclinical / mechanistic

380. Consumption of a low-carbohydrate and high-fat diet (the ketogenic diet) exaggerates biotin deficiency in mice.

Yuasa M, Matsui T, Ando S, Ishii Y, Sawamura H, Ebara S, Watanabe T · Nutrition (Burbank, Los Angeles County, Calif.) · 2012-12-27

Review

381. Ketone esters increase brown fat in mice and overcome insulin resistance in other tissues in the rat.

Veech RL · Annals of the New York Academy of Sciences · 2013-08-02

Preclinical / mechanistic

382. Fgf21 impairs adipocyte insulin sensitivity in mice fed a low-carbohydrate, high-fat ketogenic diet.

Murata Y, Nishio K, Mochiyama T, Konishi M, Shimada M, Ohta H, Itoh N · PloS one · 2013-07-09

Preclinical / mechanistic

383. Effects of a ketogenic diet during pregnancy on embryonic growth in the mouse.

Sussman D, van Eede M, Wong MD, Adamson SL, Henkelman M · BMC pregnancy and childbirth · 2013-05-08

Preclinical / mechanistic

384. A ketogenic diet increases brown adipose tissue mitochondrial proteins and UCP1 levels in mice.

Srivastava S, Baxa U, Niu G, Chen X, Veech RL · IUBMB life · 2012-12-10

Preclinical / mechanistic

385. Contribution of brain glucose and ketone bodies to oxidative metabolism.

Zhang Y, Kuang Y, LaManna JC, Puchowicz MA · Advances in experimental medicine and biology · 2012-08-11

Preclinical / mechanistic

386. The ketogenic diet increases brain glucose and ketone uptake in aged rats: a dual tracer PET and volumetric MRI study.

Roy M, Nugent S, Tremblay-Mercier J, Tremblay S, Courchesne-Loyer A, Beaudoin JF, Tremblay L, Descoteaux M, Lecomte R, Cunnane SC · Brain research · 2012-10-09

Randomized clinical trial

387. Effects of glucogenic and ketogenic feeding strategies on splanchnic glucose and amino acid metabolism in postpartum transition Holstein cows.

Larsen M, Kristensen NB · Journal of dairy science · 2012-08-23

Clinical trial / intervention

388. Effect of low-calorie versus low-carbohydrate ketogenic diet in type 2 diabetes.

Hussain TA, Mathew TC, Dashti AA, Asfar S, Al-Zaid N, Dashti HM · Nutrition (Burbank, Los Angeles County, Calif.) · 2012-06-05

Review

389. Alternative diets to the classical ketogenic diet--can we be more liberal?

Miranda MJ, Turner Z, Magrath G · Epilepsy research · 2012-07-06

Preclinical / mechanistic

390. Mitochondrial biogenesis and increased uncoupling protein 1 in brown adipose tissue of mice fed a ketone ester diet.

Srivastava S, Kashiwaya Y, King MT, Baxa U, Tam J, Niu G, Chen X, Clarke K, Veech RL · FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2012-02-23

Case report / case series

391. Successful treatment of type 1 diabetes and seizures with combined ketogenic diet and insulin.

Aguirre Castaneda RL, Mack KJ, Lteif A · Pediatrics · 2012-01-16

Case report / case series

392. Successful treatment of severe cardiomyopathy in glycogen storage disease type III With D,L-3-hydroxybutyrate, ketogenic and high-protein diet.

Valayannopoulos V, Bajolle F, Arnoux JB, Dubois S, Sannier N, Baussan C, Petit F, Labrune P, Rabier D, Ottolenghi C, Vassault A, Broissand C, Bonnet D, de Lonlay P · Pediatric research · 2011-08-23

Preclinical / mechanistic

393. Low carbohydrate ketogenic diet prevents the induction of diabetes using streptozotocin in rats.

Al-Khalifa A, Mathew TC, Al-Zaid NS, Mathew E, Dashti H · Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie · 2010-06-18

Other

394. Fibroblast growth factor 21, ketogenic diets, and insulin resistance.

Jornayvaz FR · The American journal of clinical nutrition · 2011-08-23

Preclinical / mechanistic

395. The complete control of glucose level utilizing the composition of ketogenic diet with the gluconeogenesis inhibitor, the anti-diabetic drug metformin, as a potential anti-cancer therapy.

Oleksyszyn J · Medical hypotheses · 2011-05-06

Preclinical / mechanistic

396. Central infusion of ketone bodies modulates body weight and hepatic insulin sensitivity by modifying hypothalamic leptin and insulin signaling pathways in type 2 diabetic rats.

Park S, Kim DS, Daily JW · Brain research · 2011-05-24

Guideline / consensus

397. A pilot study of the Spanish Ketogenic Mediterranean Diet: an effective therapy for the metabolic syndrome.

Pérez-Guisado J, Muñoz-Serrano A · Journal of medicinal food · 2011-05-25

Clinical trial / intervention

398. A modified Atkins diet is promising as a treatment for glucose transporter type 1 deficiency syndrome.

Ito Y, Oguni H, Ito S, Oguni M, Osawa M · Developmental medicine and child neurology · 2011-04-18

Preclinical / mechanistic

399. Hepatic steatosis, inflammation, and ER stress in mice maintained long term on a very low-carbohydrate ketogenic diet.

Garbow JR, Doherty JM, Schugar RC, Travers S, Weber ML, Wentz AE, Ezenwajiaku N, Cotter DG, Brunt EM, Crawford PA · American journal of physiology. Gastrointestinal and liver physiology · 2011-03-31

Clinical trial / intervention

400. Reversal of diabetic nephropathy by a ketogenic diet.

Poplawski MM, Mastaitis JW, Isoda F, Grosjean F, Zheng F, Mobbs CV · PloS one · 2011-04-20

Preclinical / mechanistic

401. A ketogenic diet impairs energy and glucose homeostasis by the attenuation of hypothalamic leptin signaling and hepatic insulin signaling in a rat model of non-obese type 2 diabetes.

Park S, Kim DS, Kang S, Daily JW · Experimental biology and medicine (Maywood, N.J.) · 2011-02-16

Preclinical / mechanistic

402. Proteomics analysis reveals diabetic kidney as a ketogenic organ in type 2 diabetes.

Zhang D, Yang H, Kong X, Wang K, Mao X, Yan X, Wang Y, Liu S, Zhang X, Li J, Chen L, Wu J, Wei M, Yang J, Guan Y · American journal of physiology. Endocrinology and metabolism · 2010-10-19

Preclinical / mechanistic

403. The ketogenic diet changes metabolite levels in hippocampal extracellular fluid.

Samala R, Klein J, Borges K · Neurochemistry international · 2010-11-09

Clinical trial / intervention

404. Revealing the molecular relationship between type 2 diabetes and the metabolic changes induced by a very-low-carbohydrate low-fat ketogenic diet.

Farrés J, Pujol A, Coma M, Ruiz JL, Naval J, Mas JM, Molins A, Fondevila J, Aloy P · Nutrition & metabolism · 2010-12-09

Preclinical / mechanistic

405. Seizure tests distinguish intermittent fasting from the ketogenic diet.

Hartman AL, Zheng X, Bergbower E, Kennedy M, Hardwick JM · Epilepsia · 2010-04-30

Preclinical / mechanistic

406. Insulin sensitivity and glucose tolerance are altered by maintenance on a ketogenic diet.

Kinzig KP, Honors MA, Hargrave SL · Endocrinology · 2010-04-28

Preclinical / mechanistic

407. Restricted ketogenic diet enhances the therapeutic action of N-butyldeoxynojirimycin towards brain GM2 accumulation in adult Sandhoff disease mice.

Denny CA, Heinecke KA, Kim YP, Baek RC, Loh KS, Butters TD, Bronson RT, Platt FM, Seyfried TN · Journal of neurochemistry · 2010-04-03

Case report / case series

408. Type 1 diabetes and epilepsy: efficacy and safety of the ketogenic diet.

Dressler A, Reithofer E, Trimmel-Schwahofer P, Klebermasz K, Prayer D, Kasprian G, Rami B, Schober E, Feucht M · Epilepsia · 2010-03-18

Other

409. Glucose transporter type 1 deficiency: ketogenic diet in three patients with atypical phenotype.

Veggiotti P, Teutonico F, Alfei E, Nardocci N, Zorzi G, Tagliabue A, De Giorgis V, Balottin U · Brain & development · 2009-06-09

Review

410. Ketosis and the ketogenic diet, 2010: advances in treating epilepsy and other disorders.

Freeman JM, Kossoff EH · Advances in pediatrics · 2010-11-09

Preclinical / mechanistic

411. Therapeutic role of low-carbohydrate ketogenic diet in diabetes.

Al-Khalifa A, Mathew TC, Al-Zaid NS, Mathew E, Dashti HM · Nutrition (Burbank, Los Angeles County, Calif.) · 2008-10-01

Preclinical / mechanistic

412. A very low carbohydrate ketogenic diet improves glucose tolerance in ob/ob mice independently of weight loss.

Badman MK, Kennedy AR, Adams AC, Pissios P, Maratos-Flier E · American journal of physiology. Endocrinology and metabolism · 2009-09-08

Other

413. Availability of neurotransmitter glutamate is diminished when beta-hydroxybutyrate replaces glucose in cultured neurons.

Lund TM, Risa O, Sonnewald U, Schousboe A, Waagepetersen HS · Journal of neurochemistry · 2009-05-18

Preclinical / mechanistic

414. The effects of age and ketogenic diet on local cerebral metabolic rates of glucose after controlled cortical impact injury in rats.

Prins ML, Hovda DA · Journal of neurotrauma · 2009-02-20

Preclinical / mechanistic

415. Beta-hydroxybutyrate alters GABA-transaminase activity in cultured astrocytes.

Suzuki Y, Takahashi H, Fukuda M, Hino H, Kobayashi K, Tanaka J, Ishii E · Brain research · 2009-03-11

Clinical trial / intervention

416. Metabolic response to a ketogenic breakfast in the healthy elderly.

Freemantle E, Vandal M, Tremblay Mercier J, Plourde M, Poirier J, Cunnane SC · The journal of nutrition, health & aging · 2009-03-21

Clinical trial / intervention

417. The ketogenic diet: additional information from a crossover study.

Freeman JM · Journal of child neurology · 2009-02-02

Other

418. The ketogenic diet and epilepsy: is adenosine the missing link?

Masino SA, Geiger JD · Epilepsia · 2009-02-14

Other

419. The ketogenic diet in epilepsy--monitoring of efficacy.

Cross JH · Epilepsia · 2009-02-14

Randomized clinical trial

420. A blinded, crossover study of the efficacy of the ketogenic diet.

Freeman JM, Vining EP, Kossoff EH, Pyzik PL, Ye X, Goodman SN · Epilepsia · 2008-08-19

Randomized clinical trial

421. The effect of a low-carbohydrate, ketogenic diet versus a low-glycemic index diet on glycemic control in type 2 diabetes mellitus.

Westman EC, Yancy WS, Mavropoulos JC, Marquart M, McDuffie JR · Nutrition & metabolism · 2008-12-19

Preclinical / mechanistic

422. Anticonvulsant profile of a balanced ketogenic diet in acute mouse seizure models.

Samala R, Willis S, Borges K · Epilepsy research · 2008-06-18

Preclinical / mechanistic

423. The ketogenic diet increases mitochondrial glutathione levels.

Jarrett SG, Milder JB, Liang LP, Patel M · Journal of neurochemistry · 2008-05-05

Clinical trial / intervention

424. Ketone bodies as a therapeutic for Alzheimer's disease.

Henderson ST · Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2008-07-16

Preclinical / mechanistic

425. Antioxidant capacity contributes to protection of ketone bodies against oxidative damage induced during hypoglycemic conditions.

Haces ML, Hernández-Fonseca K, Medina-Campos ON, Montiel T, Pedraza-Chaverri J, Massieu L · Experimental neurology · 2008-01-26

Case report / case series

426. Modified Atkins diet therapy for a case with glucose transporter type 1 deficiency syndrome.

Ito S, Oguni H, Ito Y, Ishigaki K, Ohinata J, Osawa M · Brain & development · 2007-09-14

Clinical trial / intervention

427. Predictive power of first morning glucose and the ketogenic diet.

Bergqvist AG, Schall JI, Richard EL, Gallagher PR, Stallings VA · Neuropediatrics · 2007-12-07

Preclinical / mechanistic

428. A high-fat, ketogenic diet induces a unique metabolic state in mice.

Kennedy AR, Pissios P, Otu H, Roberson R, Xue B, Asakura K, Furukawa N, Marino FE, Liu FF, Kahn BB, Libermann TA, Maratos-Flier E · American journal of physiology. Endocrinology and metabolism · 2007-02-13

Case report / case series

429. [Glucose transponer type 1 deficiency síndrome (GLUT-1 SD) treated with ketogenic diet. Report of one case].

Cornejo VE, Cabello JF, Colombo MC, Raimann EB · Revista medica de Chile · 2007-07-09

Preclinical / mechanistic

430. A ketogenic diet and diallyl sulfide do not elevate afterdischarge thresholds in adult kindled rats.

Nylen K, Likhodii SS, Hum KM, Burnham WM · Epilepsy research · 2006-06-19

Preclinical / mechanistic

431. Mitochondrial biogenesis in the anticonvulsant mechanism of the ketogenic diet.

Bough KJ, Wetherington J, Hassel B, Pare JF, Gawryluk JW, Greene JG, Shaw R, Smith Y, Geiger JD, Dingledine RJ · Annals of neurology · 2006-06-30

Case report / case series

432. Reconciling diabetes management and the ketogenic diet in a child with pyruvate dehydrogenase deficiency.

Henwood MJ, Thornton PS, Preis CM, Chee C, Grimberg A · Journal of child neurology · 2006-08-12

Randomized clinical trial

433. Ketogenic low-carbohydrate diets have no metabolic advantage over nonketogenic low-carbohydrate diets.

Johnston CS, Tjonn SL, Swan PD, White A, Hutchins H, Sears B · The American journal of clinical nutrition · 2006-05-11

Preclinical / mechanistic

434. Neuronal-glial interactions in rats fed a ketogenic diet.

Melø TM, Nehlig A, Sonnewald U · Neurochemistry international · 2006-03-20

Case report / case series

435. Anesthetic management of a pediatric patient on a ketogenic diet.

Ichikawa J, Nishiyama K, Ozaki K, Ikeda M, Takii Y, Ozaki M · Journal of anesthesia · 2005-10-06

Clinical trial / intervention

436. A low-carbohydrate, ketogenic diet to treat type 2 diabetes.

Yancy WS, Foy M, Chalecki AM, Vernon MC, Westman EC · Nutrition & metabolism · 2005-12-01

Preclinical / mechanistic

437. Ketogenic diet reduces hypoglycemia-induced neuronal death in young rats.

Yamada KA, Rensing N, Thio LL · Neuroscience letters · 2005-03-22

Preclinical / mechanistic

438. A comparison of the ability of a 4:1 ketogenic diet and a 6.3:1 ketogenic diet to elevate seizure thresholds in adult and young rats.

Nylen K, Likhodii S, Abdelmalik PA, Clarke J, Burnham WM · Epilepsia · 2005-08-03

Preclinical / mechanistic

439. Management of multifactorial idiopathic epilepsy in EL mice with caloric restriction and the ketogenic diet: role of glucose and ketone bodies.

Mantis JG, Centeno NA, Todorova MT, McGowan R, Seyfried TN · Nutrition & metabolism · 2004-10-19

Observational human study

440. [The ketogenic diet in German-speaking countries: update 2003].

Klepper J, Leiendecker B, Riemann E, Baumeister FA · Klinische Padiatrie · 2004-09-30

Other

441. Effects of the ketogenic diet in the glucose transporter 1 deficiency syndrome.

Klepper J, Diefenbach S, Kohlschütter A, Voit T · Prostaglandins, leukotrienes, and essential fatty acids · 2003-06-06

Review

442. The therapeutic implications of ketone bodies: the effects of ketone bodies in pathological conditions: ketosis, ketogenic diet, redox states, insulin resistance, and mitochondrial metabolism.

Veech RL · Prostaglandins, leukotrienes, and essential fatty acids · 2003-08-10

Preclinical / mechanistic

443. Role of glucose and ketone bodies in the metabolic control of experimental brain cancer.

Seyfried TN, Sanderson TM, El-Abbadi MM, McGowan R, Mukherjee P · British journal of cancer · 2003-10-02

Other

444. A pilot trial of a low-carbohydrate, ketogenic diet in patients with type 2 diabetes.

Yancy WS, Vernon MC, Westman EC · Metabolic syndrome and related disorders · 2008-03-29

Other

445. Metabolic syndrome and low-carbohydrate ketogenic diets in the medical school biochemistry curriculum.

Feinman RD, Makowske M · Metabolic syndrome and related disorders · 2008-03-29

Preclinical / mechanistic

446. Anticonvulsant properties of acetone, a brain ketone elevated by the ketogenic diet.

Likhodii SS, Serbanescu I, Cortez MA, Murphy P, Snead OC, Burnham WM · Annals of neurology · 2003-08-02

Review

447. Perspectives on the metabolic management of epilepsy through dietary reduction of glucose and elevation of ketone bodies.

Greene AE, Todorova MT, Seyfried TN · Journal of neurochemistry · 2003-07-16

Preclinical / mechanistic

448. A ketogenic diet increases brain insulin-like growth factor receptor and glucose transporter gene expression.

Cheng CM, Kelley B, Wang J, Strauss D, Eagles DA, Bondy CA · Endocrinology · 2003-05-15

Other

449. Introduction of a ketogenic diet in young infants.

Klepper J, Leiendecker B, Bredahl R, Athanassopoulos S, Heinen F, Gertsen E, Flörcken A, Metz A, Voit T · Journal of inherited metabolic disease · 2003-01-31

Preclinical / mechanistic

450. A ketogenic diet increases protein phosphorylation in brain slices of rats.

Ziegler DR, Araújo E, Rotta LN, Perry ML, Gonçalves CA · The Journal of nutrition · 2002-03-07

Case report / case series

451. Acute pancreatitis causing death in a child on the ketogenic diet.

Stewart WA, Gordon K, Camfield P · Journal of child neurology · 2001-09-29

Preclinical / mechanistic

452. Induction of the apolipoprotein AI gene by fasting: a relationship with ketosis but not with ketone bodies.

Haas MJ, Reinacher D, Pun K, Wong NC, Mooradian AD · Metabolism: clinical and experimental · 2001-01-06

Preclinical / mechanistic

453. Dietary fat, ketosis, and seizure resistance in rats on the ketogenic diet.

Likhodii SS, Musa K, Mendonca A, Dell C, Burnham WM, Cunnane SC · Epilepsia · 2000-11-15

Preclinical / mechanistic

454. Age-dependent pathways of brain energy metabolism: the suckling rat, a natural model of the ketogenic diet.

Nehlig A · Epilepsy research · 1999-12-10

Other

455. Effects of different plasma glucose concentrations on lipolytic and ketogenic responsiveness to epinephrine in type I (insulin-dependent) diabetic subjects.

Avogaro A, Gnudi L, Valerio A, Maran A, Miola M, Opportuno A, Tiengo A, Bier DM · The Journal of clinical endocrinology and metabolism · 1993-04-01

Other

456. Pulsatile glucagon has greater hyperglycaemic, lipolytic and ketogenic effects than continuous hormone delivery in man: effect of age.

Paolisso G, Buonocore S, Gentile S, Sgambato S, Varricchio M, Scheen A, D'Onofrio F, Lefèbvre PJ · Diabetologia · 1990-05-01

Other

457. Plasma glucose, ketone bodies, insulin, glucagon and enteroglucagon in cows: diurnal variations related to ketone levels before feeding and to the ketogenic effects of feeds.

Borrebaek B, Halse K, Tveit B, Dahle HK, Ceh L · Acta veterinaria Scandinavica · 1990-01-01

Other

458. Ketogenic effects of carnitine in patients with muscular dystrophy and cytochrome oxidase deficiency.

Paulson DJ, Hoganson GE, Traxler J, Sufit R, Peters H, Shug AL · Biochemical medicine and metabolic biology · 1988-02-01

Preclinical / mechanistic

459. Antiketogenic effect of glucose per se in vivo in man and in vitro in isolated rat liver cells.

Riou JP, Beylot M, Laville M, De Parscau L, Delinger J, Sautot G, Mornex R · Metabolism: clinical and experimental · 1986-07-01

Case report / case series

460. Therapeutic effects of a ketogenic diet in Rett syndrome.

Haas RH, Rice MA, Trauner DA, Merritt TA · American journal of medical genetics. Supplement · 1986-01-01

Other

461. Enhanced glycemic responsiveness to epinephrine in insulin-dependent diabetes mellitus is the result of the inability to secrete insulin. Augmented insulin secretion normally limits the glycemic, but not the lipolytic or ketogenic, response to epinephrine in humans.

Berk MA, Clutter WE, Skor D, Shah SD, Gingerich RP, Parvin CA, Cryer PE · The Journal of clinical investigation · 1985-06-01

Preclinical / mechanistic

462. Ketogenic regulation by certain metabolites in rumen epithelium.

Giesecke D, Beck U, Emmanuel B · Comparative biochemistry and physiology. B, Comparative biochemistry · 1985-01-01

Preclinical / mechanistic

463. Hepatic gluconeogenic and ketogenic interrelationships in the lactating cow.

Aiello RJ, Kenna TM, Herbein JH · Journal of dairy science · 1984-08-01

Other

464. Hormonal and metabolic changes induced by an isocaloric isoproteinic ketogenic diet in healthy subjects.

Fery F, Bourdoux P, Christophe J, Balasse EO · Diabete & metabolisme · 1982-12-01

Other

465. Modification of haloalkane-induced hepatotoxicity by exogenous ketones and metabolic ketosis.

Hewitt WR, Miyajima H, Côté MG, Plaa GL · Federation proceedings · 1980-11-01

Preclinical / mechanistic

466. A possible mechanism for the anti-ketogenic action of alanine in the rat.

Nosadini R, Datta H, Hodson A, Alberti KG · The Biochemical journal · 1980-08-15

Review

467. The ketogenic diet: mechanism of anticonvulsant action.

Withrow CD · Advances in neurology · 1980-01-01

Preclinical / mechanistic

468. Protective effects of ketogenic diets on signs of hypoglycemia.

Johnson WA, Weiner MW · Diabetes · 1978-11-01

Other

469. Hepatic mitochondrial function in ketogenic states. Diabetes, starvation, and after growth hormone administration.

DiMarco JP, Hoppel C · The Journal of clinical investigation · 1975-06-01

Preclinical / mechanistic

470. Experimental hyperosmolar diabetic syndrome. Ketogenic response to medium-chain triglycerides.

Gordon EE, Duga J · Diabetes · 1975-03-01

Preclinical / mechanistic

471. Glucogenic and ketogenic capacities of lard, safflower oil, and triumdecanoin in fasting rats.

Anderson RL, Boggs RW · The Journal of nutrition · 1975-02-01

Preclinical / mechanistic

472. An animal model for the ketogenic diet.

Appleton DB, DeVivo DC · Epilepsia · 1974-06-01

Other

473. Ketotic hypoglycemia and the ketogenic diet.

DeVivo DC, Pagliara AS, Prensky AL · Neurology · 1973-06-01

Other

474. Sporadic hypoglycemia: abnormal epinephrine response to the ketogenic diet or to insulin.

Koffler H, Schubert WK, Hug G · The Journal of pediatrics · 1971-03-01

Preclinical / mechanistic

475. Metabolic adaptations and dietary preferences in mice exposed to ketogenic and high-fat high-sucrose diets.

Penna-de-Carvalho A, Nagagata BA, Guarnieri RS, Borges MMS, Teixeira LPM, Ferreira-Machado SC, Aguila MB · Nutrition (Burbank, Los Angeles County, Calif.) · 2025-11-23

Observational human study

476. Utility of serum blood ketone levels and other risk factors for inadequate myocardial glucose suppression ketogenic FDG-PET/CT: a prospective and retrospective cohort study.

Huo YR, Gupta S, Rutherford N, Saul M, Chan MV · Annals of nuclear medicine · 2025-12-15

Randomized clinical trial

477. Adaptive Ketogenic-Mediterranean Protocol (AKMP) in Real Clinical Practice: 14-Week Pre-Post Cohort Study on Glucolipid Markers and Safety.

García-Gorrita C, San Onofre N, Merino-Torres JF, Soriano JM · Nutrients · 2025-11-14

Clinical trial / intervention

478. Induction of a metabolic switch from glucose to ketone metabolism programs ketogenic diet-induced therapeutic vulnerability in lung cancer.

Wu Z, Wang Z, Ng SQ, Lidster JA, Schwerd-Kleine P, Phua ZJC, Peh KLE, Ho YY, Yuan J, Shathishwaran S, Yeo XH, Zhang Y, Chiu YHJ, Lau LYE, Lim TKH, Takano A, Tan EH, Skanderup AJ, Tergaonkar V, Han W, Ho YS, Tan DSW, Tam WL · Cell metabolism · 2025-10-24

Randomized clinical trial

479. Effect of ketogenic diet plus dulaglutide on glucose and lipid metabolism in diabetes mellitus.

Gao R, Yan L, Du X, He S, Xue L, Li T, Wei M, Gu Y · Pakistan journal of pharmaceutical sciences · 2025-11-16

Clinical trial / intervention

480. Ketogenic diet in the management of disease.

Luong T, Svart M, Gormsen LC, Søndergaard E · Current opinion in clinical nutrition and metabolic care · 2025-08-07

Observational human study

481. Efficacy and tolerability of a low-glycemic-index ketogenic diet in Angelman syndrome: findings from the DIANE study.

Iglesias Escalera G, Cazorla Calleja R, Lorenzo Ruiz M, Lara Herguedas J, Gutiérrez Junquera C, Cilleruelo Pascual ML, Caballero-Bermejo AF, Roman-Riechmann E, Pascual Pascual SI, Ruiz-Antorán B, DIANE Study Group · Orphanet journal of rare diseases · 2025-10-21

Preclinical / mechanistic

482. Sex Differences in Ketogenic Diet Response Reveal Gonadal Hormone Interaction With FGF21 in Mice.

Zhang Y, Cochran JD, Souvenir RA, Tai W, Xia R, Gladwin BS, Barton NB, Pereira RO, Abel ED · Journal of the Endocrine Society · 2025-08-18

Clinical trial / intervention

483. A long-term ketogenic diet causes hyperlipidemia, liver dysfunction, and glucose intolerance from impaired insulin secretion in mice.

Gallop MR, Vieira RFL, Mower PD, Matsuzaki ET, Liou W, Smart FE, Roberts S, Evason KJ, Holland WL, Chaix A · Science advances · 2025-09-19

Clinical trial / intervention

484. Sustained metabolic improvements in a remotely delivered ketogenic nutrition programme for veterans with type 2 diabetes: A 3-year observational study.

Adams RN, Athinarayanan SJ, Zoller AR, McKenzie AL, Ratner RE · Diabetes, obesity & metabolism · 2025-06-16

Clinical trial / intervention

485. The role of intermittent fasting and ketogenic diet in metabolic syndrome and type 2 diabetes.

Delrue C, Speeckaert R, Speeckaert MM · Acta clinica Belgica · 2025-07-30

Guideline / consensus

486. Ketogenic diet therapy for epilepsy during pregnancy and lactation: An international survey exploring clinician perspectives.

Faltersack K, McDonald TJW, De Giorgis V, Barron B, Cervenka MC, Devlin A, Healy LA, Kverneland M, van der Louw E, Lu M, Zanaboni MP, Armeno M, Felton EA · Epilepsia open · 2025-05-29

Preclinical / mechanistic

487. Chronic stress inhibits weight gain and decreases beta-hydroxybutyrate levels and glucose tolerance in female BALB/c fed a high-fat ketogenic diet.

Cantú-Ruiz AL, Caballero-Hernández D, Gutierrez-Leal I, Martínez-Torres AC, Gomez-Flores R, Tamez-Guerra P, Tamez-Guerra R, Rodríguez-Padilla C · BMC nutrition · 2025-07-25

Other

488. A primary mechanism for efficacy of the ketogenic diet may be energy repletion at the tripartite synapse.

Joshi SN, Joshi AN, Joshi ND · Journal of neural engineering · 2025-07-24

Clinical trial / intervention

489. Rosuvastatin Improved LDL Subfractions Profile in a Patient with Type 1 Diabetes Following a Ketogenic Diet: A Case Report.

Janić M, Lunder M, Janež A, Šabović M, Maggio V, Rizzo M · Current vascular pharmacology · 2025-07-02

Other

490. A Case Report on the Metabolic Effects of a Very-Low-Carbohydrate Ketogenic Diet in a Patient With HNF1A-Related Maturity-Onset Diabetes of the Young.

Sheikh A, Nasir S, Flanagan C, Sibal L · Diabetes spectrum : a publication of the American Diabetes Association · 2025-06-17

Randomized clinical trial

491. Effects of a continuous remote care intervention including nutritional ketosis on kidney function and inflammation in adults with type 2 diabetes: a post-hoc latent class trajectory analysis.

Athinarayanan SJ, Roberts CGP, Phinney SD, Weimbs T, Friedman AN, Volek JS · Frontiers in nutrition · 2025-06-06

Preclinical / mechanistic

492. Antiproliferative effect of ketogenic diet on hormone independent mammary gland carcinoma via harnessing glucose metabolism: In-vitro and In-vivo investigations.

Yadav S, Neha, Arman M, Kumar A, Sonkar AB, Shrivastava NK, Singh J, Ansari MN, Aldossary SA, Saeedan AS, Kaithwas G · Journal, genetic engineering & biotechnology · 2025-03-23

Review

493. Therapeutic Applications of Ketogenic Diets in Lipedema: A Narrative Review of Current Evidence.

Sanlier N, Baltacı S · Current obesity reports · 2025-05-26

Other

494. Integrated microfluidic colorimetric patch with auto-framing APP for multiplex temporal detection of ketone bodies in sweat.

Xue T, Shen J, Lin W, Zhou J, Zhang X, Chen CJ, Liu JT, Zhu G · Lab on a chip · 2025-05-13

Clinical trial / intervention

495. Illnesses associated with ketosis including diabetic ketoacidosis during very low carbohydrate and ketogenic diets.

Roberts CGP, Athinarayanan SJ, Ratner RE, Umpierrez GE · Diabetes, obesity & metabolism · 2025-02-25

Clinical trial / intervention

496. A ketogenic diet decreases sevoflurane-induced burst suppression in rats.

Siegmann MJ, Parry S, Lark ARS, Mir FA, Choi J, Carpenter AH, Crowley EA, White CG, Kang J, Purdon PL, Nehs CJ · Brain research bulletin · 2025-02-24

Review

497. Ketogenic diet combined with intermittent fasting: an option for type 2 diabetes remission?

Zhou XY, Guo KH, Huang SF, Liu RK, Zeng CP · Nutrition reviews · 2025-01-10

Preclinical / mechanistic

498. A ketogenic diet enhances aerobic exercise adaptation and promotes muscle mitochondrial remodeling in hyperglycemic mice.

Pattamaprapanont P, Nava RC, Formato M, Cooney EM, Pinto AP, Alves-Wagner AB, Das A, Guan Y, Lessard SJ · Research square · 2025-01-29

Clinical trial / intervention

499. Impact of Ketogenic and Mediterranean Diets on Gut Microbiota Profile and Clinical Outcomes in Drug-Naïve Patients with Diabesity: A 12-Month Pilot Study.

Palmas V, Deledda A, Heidrich V, Sanna G, Cambarau G, Fosci M, Puglia L, Cappai EA, Lai A, Loviselli A, Manzin A, Velluzzi F · Metabolites · 2025-01-06

Systematic review / meta-analysis

500. Impact of Ketogenic Diet on Weight, Metabolic, and Endocrine Parameters in Women with Polycystic Ovary Syndrome: A Systematic Review and Meta-Analysis.

Turetta C, Turetta C, Giannini A, Tarsitano MG, Gianfrilli D, Paoli A, Kontopantelis E, De Angelis E, Minnetti M, Poggiogalle E, Colizza A, De Vincentiis M, Laganà AS, Bogani G, Palaia I, Muzii L, Di Donato V · Gynecologic and obstetric investigation · 2025-02-20

MASLD / Metabolic Liver Disease Recent peer-reviewed literature

Source-audited references from the connected PDF archive. Only papers directly relevant to this topic and ketogenic therapy/ketosis are shown.

1. Leptin/Adiponectin Ratio as a new multidimensional biomarker in obese patients with liver steatosis undergoing VLEKT

Bibliographic record reviewed for inclusion in the curated Scientific Library.

2. Very Low Energy Ketogenic Diet vs Mediterranean Diet for MASLD: Superior Steatosis Reduction in a Randomised Pilot Study

Bibliographic record reviewed for inclusion in the curated Scientific Library.

3. Ketogenic diets in MASLD: methodological limitations and the confounding role of protein intake

Bibliographic record reviewed for inclusion in the curated Scientific Library.

4. Ketogenic diets and metabolic dysfunction-associated steatotic liver disease: a literature review

Bibliographic record reviewed for inclusion in the curated Scientific Library.

5. Ketogenic Diet in Steatotic Liver Disease: A Metabolic Approach to Hepatic Health

Bibliographic record reviewed for inclusion in the curated Scientific Library.

6. Effect of a Ketogenic Diet on Metabolic Dysfunction-Associated Steatotic Liver Disease

Bibliographic record reviewed for inclusion in the curated Scientific Library.

7. An 8-Week Very Low-Calorie Ketogenic Diet Alters the Landscape of Obese-Derived Small Extracellular Vesicles, Redefining Hepatic Cell Phenotypes

Bibliographic record reviewed for inclusion in the curated Scientific Library.

8. Targeting ketone body metabolism to treat fatty liver disease

Bibliographic record reviewed for inclusion in the curated Scientific Library.

9. Beneficial Effects of the Ketogenic Diet on Nonalcoholic Fatty Liver Disease

Bibliographic record reviewed for inclusion in the curated Scientific Library.

10. Ketogenic diet time-dependently prevents NAFLD

Bibliographic record reviewed for inclusion in the curated Scientific Library.

11. Higher-Level Steatosis Is Associated with a Greater Decrease in Metabolic Dysfunction-Associated Steatotic Liver Disease after Eight Weeks of a Very Low-Calorie Ketogenic Diet

Bibliographic record reviewed for inclusion in the curated Scientific Library.

12. β-hydroxybutyrate: A crucial therapeutic target for diverse liver diseases

Bibliographic record reviewed for inclusion in the curated Scientific Library.

13. Investigating the Link between Ketogenic Diet, NAFLD, Mitochondria, and Oxidative Stress

Bibliographic record reviewed for inclusion in the curated Scientific Library.

14. Impaired ketogenesis is associated with metabolic-associated fatty liver disease in subjects with type 2 diabetes

Bibliographic record reviewed for inclusion in the curated Scientific Library.

15. Current Evidence Concerning Effects of Ketogenic Diet and Intermittent Fasting in Patients with Nonalcoholic Fatty Liver Disease

Bibliographic record reviewed for inclusion in the curated Scientific Library.

16. Emerging Role of Hepatic Ketogenesis in Fatty Liver Disease

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Human clinical study · 2026

17. Leptin/Adiponectin Ratio as a New Multidimensional Biomarker in Obese Patients with Liver Steatosis Undergoing Very Low-Energy Ketogenic Therapy

Original publication title: Leptin/Adiponectin Ratio as a New Multidimensional Biomarker in Obese Patients with Liver Steatosis Undergoing Very Low-Energy Ketogenic Therapy

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Randomized pilot study · 2026

18. Very Low-Energy Ketogenic Diet versus Mediterranean Diet for MASLD: Superior Steatosis Reduction in a Randomised Pilot Study

Original publication title: Very Low-Energy Ketogenic Diet versus Mediterranean Diet for MASLD: Superior Steatosis Reduction in a Randomised Pilot Study

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Review / evidence synthesis · 2026

19. The Impact of Dietary Interventions on Liver Health Biomarkers in Individuals with Metabolic Dysfunction-Associated Steatotic Liver Disease

Original publication title: The Impact of Dietary Interventions on Liver Health Biomarkers in Individuals with Metabolic Dysfunction-Associated Steatotic Liver Disease

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Systematic review of RCTs · 2026

20. Efficacy and Safety of Lower-Carbohydrate Dietary Patterns for Metabolic-Associated Fatty Liver Disease: Evidence from Randomized Controlled Trials with GRADE Analysis

Original publication title: Efficacy and Safety of Lower-Carbohydrate Dietary Patterns for Metabolic-Associated Fatty Liver Disease: Evidence from Randomized Controlled Trials with GRADE Analysis

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Preclinical mechanistic study · 2024

21. Ketogenic Diet Time-Dependently Prevents NAFLD through Metabolic Remodeling

Original publication title: Ketogenic Diet Time-Dependently Prevents NAFLD through Metabolic Remodeling

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Human clinical study · 2024

22. Higher-Level Steatosis Is Associated with a Greater Decrease in MASLD after Eight Weeks of a Very Low-Calorie Ketogenic Diet in Subjects with Overweight or Obesity

Original publication title: Higher-Level Steatosis Is Associated with a Greater Decrease in MASLD after Eight Weeks of a Very Low-Calorie Ketogenic Diet in Subjects with Overweight or Obesity

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Human clinical study

23. Treatment of NAFLD with Intermittent Calorie Restriction or Low-Carbohydrate Diet

Original publication title: Treatment of NAFLD with Intermittent Calorie Restriction or Low-Carbohydrate Diet

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Systematic review / meta-analysis

24. The Effect of a Ketogenic Diet on Liver Health: A Systematic Review and Meta-Analysis.

Qu Y, Sohouli MH, Rohani P, Cerqueira HS, Gomes GK, Santos HO · Nutrition reviews · 2026-07-10

Other

25. Reply to: "Ketogenic diets in MASLD: methodological limitations and the confounding role of protein intake".

Qadri SF, Yki-Järvinen H, Luukkonen PK · Journal of hepatology · 2026-06-02

Clinical trial / intervention

26. The effects of ketogenic diet and calorie-restricted diet on metabolic dysfunction-associated steatotic liver disease: a retrospective study.

Sun WJ, Xing LL, Zhao SF, Ying HM · Frontiers in nutrition · 2026-05-05

Randomized clinical trial

27. Long-Term Fructose Intake Induces Moderate Liver Inflammation but Does not Overlap with the Detrimental Effects of the Ketogenic Diet on Hepatic Steatosis in Rats.

de Souza JG, Gurgel GG, Rodrigues FM, Braga RAM, Soares RAM, Lage LAPC, Soares IC, Levy D, Damasceno NRT · Inflammation · 2026-03-23

Clinical trial / intervention

28. Impaired hepatic BMAL1-FGF21 signaling drives adverse metabolic outcomes of ketogenic diet.

Yang M, Guo Y, Du J, Li C, Bai H, Guo Y, Tan Y, Li X, Ren D, Li J, Zhang X, Zhang P, Wu G · Life sciences · 2026-03-18

Randomized clinical trial

29. Very low energy ketogenic diet vs. Mediterranean diet for MASLD: Superior steatosis reduction in a randomised pilot study.

Farrell AM, Paris T, Parr EB, George ES, Howell J, Croagh C, Sutherland T, Page M, McKelvie P, Thompson AJ, Ryan M · JHEP reports : innovation in hepatology · 2026-02-19

Other

30. Ketogenic diets in MASLD: Methodological limitations and the confounding role of protein intake.

Zhu J, Pan L, Mou L · Journal of hepatology · 2026-02-19

Clinical trial / intervention

31. Distinct effects of ketogenic and non-ketogenic weight-loss diets on hepatic steatosis and mitochondrial metabolism in MASLD.

Qadri SF, Porthan K, Dufour S, Lehtimäki TE, Petersen KF, Shulman GI, Yki-Järvinen H, Luukkonen PK · Journal of hepatology · 2026-02-06

Preclinical / mechanistic

32. Effective reduction in seizure severity and prevention of a fatty liver by a novel low ratio ketogenic diet composition in the rapid kindling rat model of epileptogenesis.

Meeusen H, Kalf RS, Broekaart DWM, Silva JP, Verkuyl JM, van Helvoort A, Gorter JA, van Vliet EA, Aronica E · Experimental neurology · 2024-06-12

Review

33. Beneficial Effects of the Ketogenic Diet on Nonalcoholic Fatty Liver Disease (NAFLD/MAFLD).

Dyńka D, Rodzeń Ł, Rodzeń M, Łojko D, Kraszewski S, Ibrahim A, Hussey M, Deptuła A, Grzywacz Ż, Ternianov A, Unwin D · Journal of clinical medicine · 2024-08-17

Other

34. Letter to the Editor: Ketogenic diet time-dependently prevents nonalcoholic fatty liver disease through upregulating the expression of antioxidant protein metallothionein-2.

Silva MLD, Souza SL, Silva JMLD, Silva RFD, Barros WMA · Clinical nutrition (Edinburgh, Scotland) · 2024-07-02

Preclinical / mechanistic

35. Ketogenic diet time-dependently prevents NAFLD through upregulating the expression of antioxidant protein metallothionein-2.

You Y, Huang Y, Wang X, Ni H, Ma Q, Ran H, Cai J, Lin X, Luo T, Wu C, Xiao X, Ma L · Clinical nutrition (Edinburgh, Scotland) · 2024-04-22

Clinical trial / intervention

36. Gender Differences in Liver Steatosis and Fibrosis in Overweight and Obese Patients with Metabolic Dysfunction-Associated Steatotic Liver Disease before and after 8 Weeks of Very Low-Calorie Ketogenic Diet.

Rinaldi R, De Nucci S, Donghia R, Donvito R, Cerabino N, Di Chito M, Penza A, Mongelli FP, Shahini E, Zappimbulso M, Pesole PL, Coletta S, Triggiani V, Cozzolongo R, Giannelli G, De Pergola G · Nutrients · 2024-05-08

Clinical trial / intervention

37. Role of liver FGF21-KLB signaling in ketogenic diet-induced amelioration of hepatic steatosis.

Guo W, Cao H, Shen Y, Li W, Wang W, Cheng L, Cai M, Xu F · Nutrition & diabetes · 2024-04-12

Preclinical / mechanistic

38. Exploring the impacts of ketogenic diet on reversible hepatic steatosis: initial analysis in male mice.

Ravaut G, Carneiro A, Mounier C · Frontiers in nutrition · 2024-03-21

Other

39. Higher-Level Steatosis Is Associated with a Greater Decrease in Metabolic Dysfunction-Associated Steatoic Liver Disease after Eight Weeks of a Very Low-Calorie Ketogenic Diet (VLCKD) in Subjects Affected by Overweight and Obesity.

Sila A, De Nucci S, Bonfiglio C, Di Stasi V, Cerabino N, Di Chito M, Rinaldi R, Cantalice P, Shahini E, Giannuzzi V, Pesole PL, Coletta S, Tutino NM, Piazzolla G, Cozzolongo R, Giannelli G, De Pergola G · Nutrients · 2024-03-18

Other

40. Ketone bodies promote epididymal white adipose expansion to alleviate liver steatosis in response to a ketogenic diet.

Zhao MF, Zhang XG, Tang YP, Zhu YX, Nie HY, Bu DD, Fang L, Li CJ · The Journal of biological chemistry · 2024-01-03

Clinical trial / intervention

41. Effects of an Eight Week Very Low-Calorie Ketogenic Diet (VLCKD) on White Blood Cell and Platelet Counts in Relation to Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) in Subjects with Overweight and Obesity.

De Nucci S, Bonfiglio C, Donvito R, Di Chito M, Cerabino N, Rinaldi R, Sila A, Shahini E, Giannuzzi V, Pesole PL, Coletta S, Lanzilotta E, Piazzolla G, Cozzolongo R, Giannelli G, De Pergola G · Nutrients · 2023-10-21

Review

42. Investigating the Link between Ketogenic Diet, NAFLD, Mitochondria, and Oxidative Stress: A Narrative Review.

Paoli A, Cerullo G · Antioxidants (Basel, Switzerland) · 2023-05-08

Other

43. Malonylation of Acetyl-CoA carboxylase 1 promotes hepatic steatosis and is attenuated by ketogenic diet in NAFLD.

Cao H, Cai Q, Guo W, Su Q, Qin H, Wang T, Xian Y, Zeng L, Cai M, Guan H, Chen S, Liang H, Xu F · Cell reports · 2023-03-31

Other

44. The ketogenic diet maintains insulin sensitivity and inhibits lipid accumulation in the liver.

King AN, Notaro NM · The Journal of physiology · 2022-10-06

Clinical trial / intervention

45. The ketogenic diet prevents steatosis and insulin resistance by reducing lipogenesis, diacylglycerol accumulation and protein kinase C activity in male rat liver.

Jani S, Da Eira D, Stefanovic M, Ceddia RB · The Journal of physiology · 2022-09-04

Clinical trial / intervention

46. Current Evidence Concerning Effects of Ketogenic Diet and Intermittent Fasting in Patients with Nonalcoholic Fatty Liver.

Sripongpun P, Churuangsuk C, Bunchorntavakul C · Journal of clinical and translational hepatology · 2022-05-06

Clinical trial / intervention

47. Probiotics counteract hepatic steatosis caused by ketogenic diet and upregulate AMPK signaling in a model of infantile epilepsy.

Mu C, Nikpoor N, Tompkins TA, Rho JM, Scantlebury MH, Shearer J · EBioMedicine · 2022-02-09

Randomized clinical trial

48. A dietary ketone ester mitigates histological outcomes of NAFLD and markers of fibrosis in high-fat diet fed mice.

Moore MP, Cunningham RP, Davis RAH, Deemer SE, Roberts BM, Plaisance EP, Rector RS · American journal of physiology. Gastrointestinal and liver physiology · 2021-01-27

Randomized clinical trial

49. Efficacy of a 2-Month Very Low-Calorie Ketogenic Diet (VLCKD) Compared to a Standard Low-Calorie Diet in Reducing Visceral and Liver Fat Accumulation in Patients With Obesity.

Cunha GM, Guzman G, Correa De Mello LL, Trein B, Spina L, Bussade I, Marques Prata J, Sajoux I, Countinho W · Frontiers in endocrinology · 2020-09-14

Clinical trial / intervention

50. Very Low-Carbohydrate Ketogenic Diet for the Treatment of Severe Obesity and Associated Non-Alcoholic Fatty Liver Disease: The Role of Sex Differences.

D'Abbondanza M, Ministrini S, Pucci G, Nulli Migliola E, Martorelli EE, Gandolfo V, Siepi D, Lupattelli G, Vaudo G · Nutrients · 2020-09-09

Clinical trial / intervention

51. Beneficial effects of the ketogenic diet on nonalcoholic fatty liver disease: A comprehensive review of the literature.

Watanabe M, Tozzi R, Risi R, Tuccinardi D, Mariani S, Basciani S, Spera G, Lubrano C, Gnessi L · Obesity reviews : an official journal of the International Association for the Study of Obesity · 2020-03-24

Other

52. Effect of a ketogenic diet on hepatic steatosis and hepatic mitochondrial metabolism in nonalcoholic fatty liver disease.

Luukkonen PK, Dufour S, Lyu K, Zhang XM, Hakkarainen A, Lehtimäki TE, Cline GW, Petersen KF, Shulman GI, Yki-Järvinen H · Proceedings of the National Academy of Sciences of the United States of America · 2020-03-16

Case report / case series

53. Ketogenic Diet-induced Elevated Cholesterol, Elevated Liver Enzymes and Potential Non-alcoholic Fatty Liver Disease.

Anekwe CV, Chandrasekaran P, Stanford FC · Cureus · 2020-01-08

Review

54. Nutritional Ketosis for Weight Management and Reversal of Metabolic Syndrome.

Gershuni VM, Yan SL, Medici V · Current nutrition reports · 2018-08-22

Clinical trial / intervention

55. Treatment of Diabetic Mice with a Combination of Ketogenic Diet and Aerobic Exercise via Modulations of PPARs Gene Programs.

Zhang Q, Xu L, Xia J, Wang D, Qian M, Ding S · PPAR research · 2018-03-20

Review

56. [Ketogenic diets : the miraculous solution ?].

Kosinski C, Jornayvaz FR · Revue medicale suisse · 2017-06-23

Preclinical / mechanistic

57. Ketogenic diet attenuates hepatopathy in mouse model of respiratory chain complex III deficiency caused by a Bcs1l mutation.

Purhonen J, Rajendran J, Mörgelin M, Uusi-Rauva K, Katayama S, Krjutskov K, Einarsdottir E, Velagapudi V, Kere J, Jauhiainen M, Fellman V, Kallijärvi J · Scientific reports · 2017-04-19

Observational human study

58. Is ketogenic diet treatment hepatotoxic for children with intractable epilepsy?

Arslan N, Guzel O, Kose E, Yılmaz U, Kuyum P, Aksoy B, Çalık T · Seizure · 2016-11-13

Case report / case series

59. Hepatic Dysfunction as a Complication of Combined Valproate and Ketogenic Diet.

Stevens CE, Turner Z, Kossoff EH · Pediatric neurology · 2015-10-24

Clinical trial / intervention

60. Role of choline deficiency in the Fatty liver phenotype of mice fed a low protein, very low carbohydrate ketogenic diet.

Schugar RC, Huang X, Moll AR, Brunt EM, Crawford PA · PloS one · 2013-08-29

Other

61. The impact of a ketogenic diet and liver dysfunction on serum very long-chain fatty acids levels.

Stradomska TJ, Bachański M, Pawłowska J, Syczewska M, Stolarczyk A, Tylki-Szymańska A · Lipids · 2013-01-31

Preclinical / mechanistic

62. A very low carbohydrate ketogenic diet prevents the progression of hepatic steatosis caused by hyperglycemia in a juvenile obese mouse model.

Okuda T, Morita N · Nutrition & diabetes · 2012-11-12

Clinical trial / intervention

63. Low-carbohydrate ketogenic diets, glucose homeostasis, and nonalcoholic fatty liver disease.

Schugar RC, Crawford PA · Current opinion in clinical nutrition and metabolic care · 2012-05-24

Preclinical / mechanistic

64. Hepatic steatosis, inflammation, and ER stress in mice maintained long term on a very low-carbohydrate ketogenic diet.

Garbow JR, Doherty JM, Schugar RC, Travers S, Weber ML, Wentz AE, Ezenwajiaku N, Cotter DG, Brunt EM, Crawford PA · American journal of physiology. Gastrointestinal and liver physiology · 2011-03-31

Clinical trial / intervention

65. The effect of a low-carbohydrate, ketogenic diet on nonalcoholic fatty liver disease: a pilot study.

Tendler D, Lin S, Yancy WS, Mavropoulos J, Sylvestre P, Rockey DC, Westman EC · Digestive diseases and sciences · 2007-01-12

Observational human study

66. Complications of the ketogenic diet.

Ballaban-Gil K, Callahan C, O'Dell C, Pappo M, Moshé S, Shinnar S · Epilepsia · 1998-07-22

Observational human study

67. Very low energy ketogenic therapy: an anti-inflammatory medical nutritional approach for MASLD in obesity.

Barrea L, Verde L, Galasso M, Savastano S, Colao A, Muscogiuri G · Journal of translational medicine · 2025-12-17

Preclinical / mechanistic

68. Adipocyte-specific deletion of gp130 prevents ketogenic diet-induced hepatic steatosis.

Senkalfa B, Gloor M, Podlaszewski R, Dewal RS, Horvath C, Efthymiou V, Ghosh A, Wueest S, Konrad D, Wolfrum C, Challa TD · Hepatology communications · 2025-08-26

Clinical trial / intervention

69. Ketogenic diet ameliorates MASLD via balancing mitochondrial dynamics and improving mitochondrial dysfunction.

You Y, Ni H, Ma Q, Jiang L, Cai J, He W, Lin X, Li K, Wang Z, Yan W, Xiao X, Ma L · Nutrition & diabetes · 2025-08-25

Randomized clinical trial

70. Beyond Weight Loss: Comparative Effects of Tirzepatide Plus Low-Energy Ketogenic Versus Low-Calorie Diet on Hepatic Steatosis and Stiffness in MASLD.

Schiavo L, Santella B, Mingo M, Rossetti G, Orio M, Pilone V · Nutrients · 2025-07-24

Clinical trial / intervention

71. Advancing Obesity Management: the Very Low-Energy Ketogenic therapy (VLEKT) as an Evolution of the "Traditional" Ketogenic Diet.

Balestra F, Luca M, Panzetta G, Palieri R, Shahini E, Giannelli G, Pergola G, Scavo MP · Current obesity reports · 2025-04-03

Preclinical / mechanistic

72. Vegetal oil-based ketogenic diet improves inflammation and fibrosis in experimental metabolic dysfunction-associated steatohepatitis.

Provera A, Ramavath NN, Gadipudi LL, Vecchio C, Caputo M, Antonioli A, Tini S, Sheferaw AN, Reano S, Filigheddu N, Manfredi M, Barberis E, Cocolin L, Ferrocino I, Locatelli M, Caprio M, Tacke F, Albano E, Prodam F, Sutti S · Frontiers in immunology · 2025-04-01

Randomized clinical trial

73. Effect of a Ketogenic Diet on Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) Progression: A Randomized Controlled Trial.

Chirapongsathorn S, Rintaravitoon W, Tangjaturonrasme B, Chotsriluecha S, Pumsutas Y, Kanchanapradith A, Treeprasertsuk S · JGH open : an open access journal of gastroenterology and hepatology · 2025-01-19

Dyslipidemia & Lipid Metabolism Recent peer-reviewed literature

Expanded source-audited selection. Systematic reviews/meta-analyses and recent human evidence are placed first; older clinical and mechanistic papers follow.

Meta-analysis of RCTs

1. Very-low-carbohydrate ketogenic diet vs low-fat diet for long-term weight loss: a meta-analysis of randomised controlled trials

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Review

2. The Ketogenic Diet and Cardiovascular Diseases

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Recent human study

3. The Impact of Ketogenic Capacity on Lipid Profile in Individuals with Prediabetes or Newly Diagnosed Type 2 Diabetes

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Lipid-focused study/review

4. Low-density lipoprotein cholesterol elevation with carbohydrate-restricted diets

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Human clinical study

5. LDL Keto Trial

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Lipid-focused analysis

6. Elevated LDL Cholesterol with a Carbohydrate-Restricted Diet: Evidence

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Human metabolic study

7. Thyroid markers and body composition predict LDL-cholesterol change in lean healthy women on a ketogenic diet

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Recent human study

8. Effects of a two-week modified ketogenic diet on circulating lipoprotein subclasses, GDF15, and FGF21 in obese adults

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Clinical study

9. Reduction of Cardio-Metabolic Risk and Body Weight through a ketogenic dietary intervention

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Human intervention

10. Italian Ketogenic Mediterranean Diet in Overweight and Obese Adults

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Human intervention

11. Effects of a two-meals-a-day ketogenic diet on metabolic markers

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Comparative review/analysis

12. Is a Ketogenic Diet Superior to a Low-Fat Diet?

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Clinical evidence

13. Efficacy and safety of very low calorie ketogenic diet (VLCKD) in patients with overweight and obesity

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Review

14. Effects of ketogenic diet on health

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Meta-analysis of randomized trials

15. Very-Low-Carbohydrate Ketogenic Diet versus Low-Fat Diet for Long-Term Weight Loss: A Meta-Analysis of Randomised Controlled Trials

Original publication title: Very-Low-Carbohydrate Ketogenic Diet versus Low-Fat Diet for Long-Term Weight Loss: A Meta-Analysis of Randomised Controlled Trials

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Mechanistic / hypothesis paper

16. The Lipid Energy Model

Original publication title: The Lipid Energy Model

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Human clinical evidence

17. Reduction of Cardio-Metabolic Risk and Body Weight through Ketogenic Nutritional Intervention

Original publication title: Reduction of Cardio-Metabolic Risk and Body Weight through Ketogenic Nutritional Intervention

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Clinical / mechanistic evidence

18. Low-Density Lipoprotein Cholesterol Elevation in the Context of a Ketogenic Diet

Original publication title: Low-Density Lipoprotein Cholesterol Elevation in the Context of a Ketogenic Diet

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Human experimental study

19. Thyroid Markers and Body Composition Predict LDL-Cholesterol Change in Lean Healthy Women on a Ketogenic Diet: Experimental Support for the Lipid Energy Model

Original publication title: Thyroid Markers and Body Composition Predict LDL-Cholesterol Change in Lean Healthy Women on a Ketogenic Diet: Experimental Support for the Lipid Energy Model

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Clinical observational evidence

20. Elevated LDL Cholesterol with a Carbohydrate-Restricted Diet: Evidence for a Lean Mass Hyper-Responder Phenotype

Original publication title: Elevated LDL Cholesterol with a Carbohydrate-Restricted Diet: Evidence for a Lean Mass Hyper-Responder Phenotype

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Human metabolic study

21. Effects of a Two-Week Modified Ketogenic Diet on Circulating Lipoprotein Subclasses, GDF15, and FGF21 in Adults with Obesity

Original publication title: Effects of a Two-Week Modified Ketogenic Diet on Circulating Lipoprotein Subclasses, GDF15, and FGF21 in Adults with Obesity

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Clinical evidence

22. Increased LDL-C reduction with ezetimibe in ketogenic diet-induced hypercholesterolemia

Original publication title: Increased LDL-C reduction with ezetimibe in ketogenic diet-induced hypercholesterolemia

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Observational human study

23. [Effectiveness and tolerability of ketogenic diet therapy in children with genetic developmental and epileptic encephalopathy onset within 2 years of age].

Song TY, Deng J, Chen CH, Wang XH, Tian XJ, Wu ML, Wang X, Zhang HW, Chen XY, Wang Y, Niyazi Y, Abudureyimu G, Fang F · Zhonghua er ke za zhi = Chinese journal of pediatrics · 2026-09-15

Systematic review / meta-analysis

24. Effects of ketogenic diet on cognitive impairment in older adults: a systematic review and meta-analysis.

Xi L, Wan J, Hua Y, Guo M, Du J, Luo X, Yu H · Archives of gerontology and geriatrics · 2026-09-12

Clinical trial / intervention

25. Ketogenic diet-induced changes in hepatic drug metabolism with potential implications for ozanimod pharmacokinetics in mice.

Frybortova V, Satka S, Jourova L, Anzenbacher P, Zapletalova I, Kraus M, Kostovcikova K, Kverka M, Anzenbacherova E · PloS one · 2026-09-08

Other

26. Ketogenic Diet Promotes Intestinal Tumorigenesis Via Lipid Oxidation.

Cancer discovery · 2026-08-25

Systematic review / meta-analysis

27. Impact of medium-chain triglyceride with and without ketogenic diet in the management of drug-resistant epilepsy: a systematic review.

Pellizzari M, De Clauser L, Mir-Majidi S, Leone A, Veggiotti P, Previtali R, Olivotto S, Bertoli S, De Amicis R · Nutritional neuroscience · 2026-08-20

Preclinical / mechanistic

28. The impact of medium chain triglyceride ketogenic diet on liver mitochondria and cytochrome P450 2E1.

Ryan AS, Roberts RM, Stayer KM, Tomasevich AA, Misare KR, Hollis F, McQuail JA, Hartman JH · Archives of biochemistry and biophysics · 2026-08-19

Preclinical / mechanistic

29. Ketogenic diet attenuates seizures by promoting lipid droplet formation via peroxisome proliferator-activated receptor gamma signaling pathway.

Xi Z, Zhang W, Liu Q, Wang Q, Qi Y · Life sciences · 2026-08-19

Randomized clinical trial

30. Ketogenic effects of milk protein-coated medium-chain triglycerides in healthy men: A randomized, double-blind, crossover study.

Ito K, Kawasaki Y, Tamura K, Nakamura K, Kawai Y, Watanabe T · PloS one · 2026-08-10

Clinical trial / intervention

31. Integrative Multi-Omics Reveal Metabolic Reprogramming by Ketogenic Diet in Melanoma Xenografts.

Dnyansagar R, Bordag N, Poupardin R, Tevini J, Stefan VE, Derdak S, Bilban M, Fortelny N, Kofler B, Lang R, Weber DD · Biomolecules · 2026-07-22

Preclinical / mechanistic

32. Ketogenic diet mediates intestinal tumorigenesis through lipids not ketones.

Shay JES, Chi F, Tzouanas CN, Han S, Zhang X, Ten Hoeve J, Williams KJ, Neptun S, Sever T, Fuentes I, Bhatia SN, Calibasi-Kocal G, Vander Heiden MG, Shalek AK, Yilmaz ÖH · Nature · 2026-07-15

Clinical trial / intervention

33. Short-term ketogenic diet induces systemic lipidomic remodeling associated with metabolic adaptation in humans.

Park M, Yu JS, Jeon JY, Oh HA, Lee YH, Lee SG, Lee G · Frontiers in nutrition · 2026-07-10

Systematic review / meta-analysis

34. Ketogenic diets and cardiovascular health balancing metabolic benefits against lipid-related risk.

Liu H, Wu W, He N, Wang X, Pan S, Zhu L, Ma S, Zhang Y, Liu Z · BMC cardiovascular disorders · 2026-07-07

Systematic review / meta-analysis

35. Ketogenic Diet in the Treatment of Malignant Gliomas: A Systematic Review.

Persiani M, Dallolio L, Masini A, Longobucco Y, Bertoli S, Guberti E, Pellizzari M, Petroni ML, Valeriani F, Gallè F, Sacchetti R · Nutrients · 2026-07-03

Systematic review / meta-analysis

36. The impact of the ketogenic diet on the health of patients with metabolic syndrome: a scoping review.

Winiarska M, Wiśniewska D, Klimas M, Jucha D, Szczupak M, Kobak J, Krupa-Nurcek S · Frontiers in nutrition · 2026-06-29

Preclinical / mechanistic

37. Influence of Ketogenic Diet Lipid Composition on Anxiety-Like Behavior and Neurometabolic Profile in Healthy Rats.

Gurgel GG, de Souza JG, Braga RAM, Rodrigues FM, Faccioli AM, Fortes MEG, da Silva EA, Freitas RAMS, Arida RM, Scorza CA, Bernardes ES, Dos Santos SN, Damasceno NRT · Molecular neurobiology · 2026-06-25

Other

38. Very Low Energy Ketogenic Therapy Effects on Fibrosis-Dependent Metabolic Reprogramming: A Serum NMR Pilot Study.

Donghia R, Musio B, De Luca M, Balestra F, Panzetta G, Todisco S, Mastrorilli P, Coletta S, Di Chito M, Giannelli G, Gallo V, Scavo MP · Nutrients · 2026-06-17

Observational human study

39. Personalized Combination of a Ketogenic Diet and Low-Dose Semaglutide for Cardiometabolic Health: A Retrospective Case Series.

Parker G, Morris MD, Heggie JR, Cooper-Leavitt EF, Clark CJ, Reynolds AP, Smith HA, Wendel CP, Jensen WJ, Morris TJ, Reynolds PR, Bikman BT · Journal of personalized medicine · 2026-06-12

Clinical trial / intervention

40. Use of medium-chain triglycerides in paediatric patients with drug-resistant epilepsy without ketogenic therapy.

Viollaz R, Alberti MJ, de Clauser L, Vilavedra JF · Epilepsy & behavior : E&B · 2026-06-12

Randomized clinical trial

41. Feasibility and Safety of a Ketogenic Diet During Systemic Therapy for Metastatic Renal Cell Carcinoma: Results from the Cetorein Pilot Study.

Rolley C, Zidane M, Nedelcu C, Barth M, Saulnier P, Procaccio V, Bigot P · Nutrients · 2026-05-27

Randomized clinical trial

42. Very low-carbohydrate ketogenic diet in treatment-naïve women with endometrial cancer and overweight: a randomized feasibility study.

Dantas E, Hootman KC, Moyer J, Tomberlin M, Curran K, Ramesh B, Price H, Kim J, McPherson AC, Hurd MA, Zhu YS, Plodkowski AJ, Nagase E, Tsomides A, Cuevas BM, Martin ML, Nguyen J, Bennetti G, Rodriguez GB, Chang K, Mezzancello M, Gardner GJ, Broach V, Mueller JJ, Sonoda Y, Zivanovic O, Leitao MM, Iasonos A, Soldan K, Carthew K, Hom V, Villamater FN, Chaari RR, Gorski K, Sigouros M, Aghajanian C, Elemento O, Cantley LC, Hopkins BD, Weigelt B, Ellenson LH, Hacker K, Abu-Rustum NR, Makker V, Goncalves MD · Nature communications · 2026-05-27

Case report / case series

43. Reversible high-fat ketogenic formula-induced hypertriglyceridemia in a child with NALCN mutation on a ketogenic diet: a case report.

Elbarky A, Dawoud H, Elballat KE, Gamal H, Salamah A · Molecular biology reports · 2026-05-20

Preclinical / mechanistic

44. Fourier Transform Infrared Imaging Supported by Raman Spectroscopy Reveals Biochemical Changes in Adult Rat Brains Following Prenatal Exposure to a Ketogenic Diet.

Rugiel M, Setkowicz Z, Drozdz A, Wilk A, Brylowska Z, Chwiej J · ACS chemical neuroscience · 2026-05-19

Observational human study

45. Risks of using standard reference ranges for carbohydrate and lipid metabolism in low-carbohydrate diets: insights from ketogenic diet therapy in children with refractory epilepsy.

Matsui K, Mori M, Kumada T · Diabetology international · 2026-05-15

Randomized clinical trial

46. Effects of intermittent fasting combined with a ketogenic diet versus a hypocaloric diet on metabolic outcomes in adults with type 2 diabetes mellitus: A controlled clinical study.

Barrionuevo-Burgos E, García-García RM, Muñoz L, Arreguín-Coronado A · Nutrition and health · 2026-05-08

Observational human study

47. Gut microbiota shifts and short-chain fatty acids alterations in pediatric epilepsy patients on a Mediterranean ketogenic diet.

Zouganeli S, Mitsou EK, Yannakoulia M, Intze E, Mountzouris KC, Fessatou S, Attilakos A, Kyriacou A, Dinopoulos A · Epileptic disorders : international epilepsy journal with videotape · 2026-05-07

Systematic review / meta-analysis

48. Ketogenic diet-induced changes in adult lipid metabolism: a comprehensive systematic review and meta-regression of randomized controlled trials.

Zhao J, Wei C, Gong F, Pang Z, Zhao H · BMC cardiovascular disorders · 2026-04-30

Clinical trial / intervention

49. Ketogenic Diets and Low-Density Lipoprotein Cholesterol in Adults With Normal Weight: An Emerging Clinical Challenge.

DiMattia ZS, Petersen KS · Journal of the American Heart Association · 2026-04-28

Review

50. Ketogenic Diet in Children with Type 1 Diabetes: Parental Motivations and Potential Risks for Metabolic Health and Development.

Kovinthapillai R, Lan YY, Kędzia A, Niechciał E · Nutrients · 2026-04-15

Other

51. Can Artificial Intelligence Chatbots Plan Therapeutic Ketogenic Diets for Children With Epilepsy?

Ajmera F, Lowe H, Dickson J, Owusu K, Zak M, Sharma S · Journal of human nutrition and dietetics : the official journal of the British Dietetic Association · 2026-04-13

Other

52. Ketogenic diet synergistic reprogramming of both host and microbiome promotes tissue regeneration.

Nagai M, Band V, Chi L, Smelkinson M, Schwarz B, Brandes NT, Burns A, Perez-Chaparro PJ, McCauley KE, Corral D, Bouladoux N, Link VM, Zheng L, Constantinides MG, Otto M, Moutsopoulos NM, Belkaid Y · bioRxiv : the preprint server for biology · 2026-04-13

Randomized clinical trial

53. Conversion Bariatric Surgery, Ketogenic Diet, and Intermittent Fasting in Bariatric Surgery Patients with Recurrent Weight Gain: a Prospective Randomized Controlled Trial.

Şen S, Erdem NZ, Durak D · Obesity surgery · 2026-04-11

Observational human study

54. Clinical and laboratory outcomes of ketogenic versus glycine-restricted diet in nonketotic hyperglycinemia: A comparative study.

Bozacı AE, Erdal İ, Öner G, Clark ÖA, Köken ÖY, Soyuçen E · Molecular genetics and metabolism · 2026-04-07

Other

55. Author Correction: Consuming a modified Mediterranean ketogenic diet reverses the peripheral lipid signature of Alzheimer's disease in humans.

Neth BJ, Huynh K, Giles C, Wang T, Mellett NA, Duong T, Blach C, Schimmel L, Register TC, Blennow K, Zetterberg H, Batra R, Schweickart A, Dilmore AH, Martino C, Arnold M, Krumsiek J, Han X, Dorrestein PC, Knight R, Meikle PJ, Craft S, Kaddurah-Daouk R · Communications medicine · 2026-04-06

Clinical trial / intervention

56. Personalizing Obesity Treatment: Real-World Comparison of a Very-Low-Calorie Ketogenic Diet Versus a Whole-Food Mediterranean Ketogenic Diet.

Masi D, Spizzichini ML, Colonnello E, Vasquez Barahona D, Gnessi L, Gianfrilli D, Watanabe M · Metabolites · 2026-04-05

Preclinical / mechanistic

57. Divergent Liver and Kidney Metabolic Responses to Ketogenic, High-Fat, and Sucrose-Enriched Diets in Mice.

Grillo G, Vega N, Zaczek A, Selmi A, Chanon S, Vieille Marchiset A, Santillo A, Balcerczyk A, Strigini M, Pirola L · Nutrients · 2026-04-01

Clinical trial / intervention

58. Modulatory role of the ketogenic diet in glial scar formation after traumatic brain injury: A Fourier transform infrared, Raman, and X-ray fluorescence microscopy study.

Kawon K, Setkowicz Z, Czyzycki M, Rauk Z, Wilk A, Slawek A, Cieslak J, Aquilanti G, Carlomagno I, Drozdz A, Chwiej J · Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy · 2026-03-31

Preclinical / mechanistic

59. Targeting systemic and tumor metabolic balances with ketogenic diets enhance efficacy of therapy in FLT3-ITD acute myeloid leukemia.

Goupille L, Boudet A, Lauture L, Sahal A, Gautier-Renard G, Chu-Van E, Nguyen AL, Chollet C, Alcazar C, Bernard I, Vergez F, de Mas V, Récher C, Kaoma T, Gallipoli P, Dembitz V, Basili I, Bernardi F, Ayrault O, Joffre C, Castelli F, Colsch B, Bourgès-Abella N, Granat F, Sarry JE · Cell reports · 2026-03-28

Systematic review / meta-analysis

60. Metabolic, adherence, and sustainability outcomes of plant-based low-carbohydrate and ketogenic diets: A systematic review of clinical evidence.

Mazzola G, Rondanelli M, Cabrini C, Perna S · Nutrition (Burbank, Los Angeles County, Calif.) · 2026-03-24

Preclinical / mechanistic

61. A KETOGENIC DIET PROMOTES BLOOD-SPINAL CORD BARRIER RESEALING TO DECREASE SPINAL CORD IMMUNE CELL INFILTRATION IN A PRECLINICAL MODEL OF MULTIPLE SCLEROSIS.

Plafker KS, Walton DA, Pezant N, Plafker SM · bioRxiv : the preprint server for biology · 2026-03-24

Clinical trial / intervention

62. Leptin/Adiponectin Ratio as a new multidimensional biomarker in obese patients with liver steatosis undergoing VLEKT: results from a pilot study.

Balestra F, Donghia R, De Luca M, Stabile D, Coletta S, Panzetta G, Palieri R, Di Chito M, De Pergola G, Giannelli G, Pesole PL, Scavo MP · Frontiers in nutrition · 2026-03-20

Clinical trial / intervention

63. Impaired hepatic BMAL1-FGF21 signaling drives adverse metabolic outcomes of ketogenic diet.

Yang M, Guo Y, Du J, Li C, Bai H, Guo Y, Tan Y, Li X, Ren D, Li J, Zhang X, Zhang P, Wu G · Life sciences · 2026-03-18

Clinical trial / intervention

64. Distinct effects of ketogenic and non-ketogenic weight-loss diets on hepatic steatosis and mitochondrial metabolism in MASLD.

Qadri SF, Porthan K, Dufour S, Lehtimäki TE, Petersen KF, Shulman GI, Yki-Järvinen H, Luukkonen PK · Journal of hepatology · 2026-02-06

Systematic review / meta-analysis

65. The Impact of the Ketogenic Diet on the Lipid Profile in Adults: A Comprehensive Review and Meta-Regression Analysis of Randomized Controlled Trials.

Chang C, Liu Y, Rohani P, Khodadadi N, Prabahar K, Sohouli MH · Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists · 2026-01-30

Clinical trial / intervention

66. Ketogenic diet improves cognitive impairment in rats with temporal lobe epilepsy by activating the Nrf2/HO-1/GPX4 signaling axis to inhibit ferroptosis.

Yang L, Wang J, Wang X, Li B, Zhao D, Li C, Li C, Cui Y, Chen Q, Yang Y, Gu J, Hou S, Zhang L, Qiang Y · Free radical biology & medicine · 2026-01-21

Clinical trial / intervention

67. Complementary mechanisms of high-carbohydrate diets and ketogenic diets restore adult hippocampal neurogenesis and cognitive function in high-fat diet induced obesity in mice.

Kwon H, Seo DS, Ahmad Y, Park S, Yoo J, Lee J, Bae HJ, Jang Y · The Journal of nutritional biochemistry · 2025-12-29

Preclinical / mechanistic

68. A ketogenic diet improves memory in females in the APOE4 mouse model of Alzheimer's disease.

Di Lucente J, Rutkowsky JM, Errico Provenzano A, Persico G, Zhou Z, Jin LW, Ramsey JJ, Montgomery CB, Kim K, Giorgio M, Maezawa I, Cortopassi GA · GeroScience · 2025-11-24

Guideline / consensus

69. Low-Carbohydrate/Ketogenic Diet and Coronary Artery Disease: A Brief Review of the Limited Evidence Between Them.

Kusayev J, Weininger D, Frishman WH, Aronow WS · Cardiology in review · 2024-02-01

Observational human study

70. The effect of the modified Atkins diet and anti-seizure medications on lipid marker levels in adults with epilepsy.

Muller AL, Diaz-Arias L, Cervenka MC, McDonald TJW · Nutritional neuroscience · 2024-09-04

Preclinical / mechanistic

71. Primary components of MCT ketogenic diet are detrimental to bone loss associated with accelerated aging and age-related neurotoxicity in mice.

Jain S, Vohora D · Bone · 2024-12-26

Systematic review / meta-analysis

72. Therapeutic Potential of Ketogenic Interventions for Autosomal-Dominant Polycystic Kidney Disease: A Systematic Review.

Li D, Dawson J, Gunton JE · Nutrients · 2024-12-31

Randomized clinical trial

73. The effects of portfolio moderate-carbohydrate and ketogenic diets on anthropometric indices, metabolic status, and hormonal levels in overweight or obese women with polycystic ovary syndrome: a randomized controlled trial.

Sharifi M, Saber A, Moludi J, Salimi Y, Jahan-Mihan A · Nutrition journal · 2024-12-02

Systematic review / meta-analysis

74. The effects of ketogenic diet on metabolic and hormonal parameters in patients with polycystic ovary syndrome: a systematic review and meta-analysis of clinical trials.

Eshaghhosseiny N, Ahmadi M, Izadi B, Vali M, Akbari M, Azari I, Akbari H · Journal of diabetes and metabolic disorders · 2024-05-21

Preclinical / mechanistic

75. The beneficial impact of ketogenic diets on chemically-induced colitis in mice depends on the diet's lipid composition.

Hadžić K, Gregor A, Kofler B, Pignitter M, Duszka K · The Journal of nutritional biochemistry · 2024-08-10

Observational human study

76. The impact of carbohydrate restriction-induced elevations in low-density lipoprotein cholesterol on progression of coronary atherosclerosis: the ketogenic diet trial study design.

Javier DAR, Manubolu VS, Norwitz NG, Kinninger A, Aldana-Bitar J, Ghanem A, Ahmad K, Vicuna WD, Hamidi H, Bagheri M, Elsayed T, Villanueva B, Ichikawa K, Flores F, Hamal S, Feldman D, Budoff MJ · Coronary artery disease · 2024-06-13

Preclinical / mechanistic

77. Oral Administration of a Novel, Synthetic Ketogenic Compound Elevates Blood β-Hydroxybutyrate Levels in Mice in Both Fasted and Fed Conditions.

Soliven MA, Rogers CQ, Williams MS, Thomas NN, Turos E, D'Agostino DP · Nutrients · 2024-10-18

Preclinical / mechanistic

78. The gut microbiota changed by ketogenic diets contribute to glucose intolerance rather than lipid accumulation.

Li W, Gong M, Wang Z, Pan H, Li Y, Zhang C · Frontiers in endocrinology · 2024-09-27

Preclinical / mechanistic

79. Comparative Efficacy of Low-Carbohydrate and Ketogenic Diets on Diabetic Retinopathy and Oxidative Stress in High-Fat Diet-Induced Diabetic Rats.

Jawharji MT, Alshammari GM, Binobead MA, Albanyan NM, Al-Harbi LN, Yahya MA · Nutrients · 2024-09-12

Systematic review / meta-analysis

80. Effect of ketogenic diets on lipid metabolism in adults: protocol for a systematic review.

Hilary S, Östlundh L, Platat C, Al-Rifai RH, Almehairbi O, Alshamsi F, Ali HI, Al Dhaheri AS, Cheikh Ismail L, Stojanovska L · BMJ open · 2024-09-10

Review

81. Very Low Calorie Ketogenic Diet: What Effects on Lipid Metabolism?

Suarez R, Chapela S, Llobera ND, Montalván M, Vásquez CA, Martinuzzi ALN, Katsanos CS, Verde L, Frias-Toral E, Barrea L, Muscogiuri G · Current nutrition reports · 2024-07-15

Randomized clinical trial

82. Ketogenic diet but not free-sugar restriction alters glucose tolerance, lipid metabolism, peripheral tissue phenotype, and gut microbiome: RCT.

Hengist A, Davies RG, Walhin JP, Buniam J, Merrell LH, Rogers L, Bradshaw L, Moreno-Cabañas A, Rogers PJ, Brunstrom JM, Hodson L, van Loon LJC, Barton W, O'Donovan C, Crispie F, O'Sullivan O, Cotter PD, Proctor K, Betts JA, Koumanov F, Thompson D, Gonzalez JT · Cell reports. Medicine · 2024-08-05

Preclinical / mechanistic

83. Sex- and Age-Specific Differences in Mice Fed a Ketogenic Diet.

Sprankle KW, Knappenberger MA, Locke EJ, Thompson JH, Vinovrski MF, Knapsack K, Kolwicz SC · Nutrients · 2024-08-16

Clinical trial / intervention

84. Metabolic Effects of Ketogenic Diets: Exploring Whole-Body Metabolism in Connection with Adipose Tissue and Other Metabolic Organs.

Ahmad Y, Seo DS, Jang Y · International journal of molecular sciences · 2024-06-27

Clinical trial / intervention

85. Long-term ketogenic diet causes hyperlipidemia, liver dysfunction, and glucose intolerance from impaired insulin trafficking and secretion in mice.

Gallop MR, Vieira RFL, Matsuzaki ET, Mower PD, Liou W, Smart FE, Roberts S, Evason KJ, Holland WL, Chaix A · bioRxiv : the preprint server for biology · 2024-06-17

Preclinical / mechanistic

86. The impact of continuous and intermittent ketogenic diets on cognitive behavior, motor function, and blood lipids in TgF344-AD rats.

Rutkowsky JM, Roland Z, Valenzuela A, Nguyen AB, Park HH, Six N, Dursun I, Kim K, Lein PJ, Ramsey JJ · Aging · 2024-04-12

Other

87. The Significant Impact of High-Fat, Low-Carbohydrate Ketogenic Diet on Serum Lipid Profile and Atherosclerotic Cardiovascular Disease Risk in Overweight and Obese Adults.

Khdher S, Mohammed S, Muhammed K, Ismael A · Cureus · 2024-04-09

Randomized clinical trial

88. A randomized feasibility trial of medium chain triglyceride-supplemented ketogenic diet in people with Parkinson's disease.

Choi AH, Delgado M, Chen KY, Chung ST, Courville A, Turner SA, Yang S, Airaghi K, Dustin I, McGurrin P, Wu T, Hallett M, Ehrlich DJ · BMC neurology · 2024-04-01

Other

89. Interface chemistry affected the digestion fate of ketogenic diet based on medium- and long-chain triglycerides.

Li X, Cheng Y, Xu Z, Lin X, Xu B, Wang Z, Li P, Nian B · Food research international (Ottawa, Ont.) · 2024-02-02

Clinical trial / intervention

90. Ketogenic diet alleviates β-cell dedifferentiation but aggravates hepatic lipid accumulation in db/db mice.

Zhang M, Chen Y, Sun S, Zhang S, Yuan L, Xu Y, Li X, Chen G, Wei X, Liu C · Nutrition (Burbank, Los Angeles County, Calif.) · 2023-10-31

Systematic review / meta-analysis

91. Ketogenic diets: A systematic review of current scientific evidence and possible applicability in dogs and cats.

Vendramini THA, Amaral AR, Rentas MF, Nogueira JPDS, Pedrinelli V, de Oliveira VV, Zafalon RVA, Brunetto MA · Journal of animal physiology and animal nutrition · 2023-12-13

Other

92. Ketone bodies promote epididymal white adipose expansion to alleviate liver steatosis in response to a ketogenic diet.

Zhao MF, Zhang XG, Tang YP, Zhu YX, Nie HY, Bu DD, Fang L, Li CJ · The Journal of biological chemistry · 2024-01-03

Other

93. Oreo Cookie Treatment Lowers LDL Cholesterol More Than High-Intensity Statin therapy in a Lean Mass Hyper-Responder on a Ketogenic Diet: A Curious Crossover Experiment.

Norwitz NG, Cromwell WC · Metabolites · 2024-01-22

Randomized clinical trial

94. Changes in the chronic and postprandial blood lipid profiles of trained competitive cyclists and triathletes following a ketogenic diet: a randomized crossover trial.

Graybeal AJ, Kreutzer A, Moss K, Shah M · BMC sports science, medicine & rehabilitation · 2024-01-16

Other

95. Low carbohydrate/ketogenic diet in the optimization of lipoprotein(a) levels: do we have sufficient evidence for any recommendation?

Surma S, Sahebkar A, Banach M, endorsed by the International Lipid Expert Panel (ILEP) · European heart journal · 2023-12-17

Other

96. Predictors of elevations in fasting lipid levels in adults with epilepsy on a modified Atkins diet.

McDonald TJW, Diaz-Arias L, Vizthum D, Henry-Barron BJ, Cervenka MC · Seizure · 2023-11-21

Randomized clinical trial

97. Ketogenic propensity is differentially related to lipid-induced hepatic and peripheral insulin resistance.

Mey JT, Vandagmansar B, Dantas WS, Belmont KP, Axelrod CL, Kirwan JP · Acta physiologica (Oxford, England) · 2023-10-16

Clinical trial / intervention

98. Nutritional Intervention in Cushing's Disease: The Ketogenic Diet's Effects on Metabolic Comorbidities and Adrenal Steroids.

Guarnotta V, Amodei R, Di Gaudio F, Giordano C · Nutrients · 2023-11-02

Preclinical / mechanistic

99. Hepatic safety profile of pancreatic cancer‑bearing mice fed a ketogenic diet in combination with gemcitabine.

Cortez NE, Lanzi CR, Vahmani P, Matsukuma K, Mackenzie GG · Oncology letters · 2023-09-22

Preclinical / mechanistic

100. Ketogenic diet changes microglial morphology and the hippocampal lipidomic profile differently in stress susceptible versus resistant male mice upon repeated social defeat.

González Ibáñez F, Halvorson T, Sharma K, McKee CG, Carrier M, Picard K, Vernoux N, Bisht K, Deslauriers J, Lalowski M, Tremblay MÈ · Brain, behavior, and immunity · 2023-09-07

Observational human study

101. Effects of a two meals-a-day ketogenic diet on newly diagnosed obese patients with type 2 diabetes mellitus: A retrospective observational study.

Li S, Yuan S, Lin G, Zhang J · Medicine · 2023-11-01

Preclinical / mechanistic

102. Ketogenic diet influence on the elemental homeostasis of internal organs is gender dependent.

Kawon K, Rugiel M, Setkowicz Z, Matusiak K, Kubala-Kukus A, Stabrawa I, Szary K, Rauk Z, Chwiej J · Scientific reports · 2023-10-27

Other

103. Changes in lipids and inflammation in adults with super-refractory status epilepticus on a ketogenic diet.

Dickens AM, Johnson TP, Lamichhane S, Kumar A, Pardo CA, Gutierrez EG, Haughey N, Cervenka MC · Frontiers in molecular biosciences · 2023-10-23

Preclinical / mechanistic

104. Erratum: Update Notice: Computational Analysis of Plasma Lipidomics from Mice Fed Standard Chow and Ketogenic Diet.

Seufert AL, Hickman JW, Choi J, Napier BA · Bio-protocol · 2023-10-20

Systematic review / meta-analysis

105. Effects of very low-carbohydrate ketogenic diets on lipid profiles in normal-weight (body mass index < 25 kg/m2) adults: a meta-analysis.

Joo M, Moon S, Lee YS, Kim MG · Nutrition reviews · 2023-10-11

Randomized clinical trial

106. Corrigendum: Weight, insulin resistance, blood lipids, and diet quality changes associated with ketogenic and ultra low-fat dietary patterns: a secondary analysis of the DIETFITS randomized clinical trial.

Aronica L, Landry MJ, Rigdon J, Gardner CD · Frontiers in nutrition · 2023-10-09

Other

107. Antioxidant and antilipidemic action of ketogenic diet and tomato powder mix in high sugar and fat fed Harwich fruit flies.

Kayode OT, Afolabi OA, Ajayi GO · Heliyon · 2023-09-24

Preclinical / mechanistic

108. The ketogenic diet promotes triacylglycerol recycling in white adipose tissue and uncoupled fat oxidation in brown adipose tissue, but does not reduce adiposity in rats.

Da Eira D, Jani S, Stefanovic M, Ceddia RB · The Journal of nutritional biochemistry · 2023-07-06

Systematic review / meta-analysis

109. Ketogenic Diet and Multiple Health Outcomes: An Umbrella Review of Meta-Analysis.

Chen S, Su X, Feng Y, Li R, Liao M, Fan L, Liu J, Chen S, Zhang S, Cai J, Zhu S, Niu J, Ye Y, Lo K, Zeng F · Nutrients · 2023-09-27

Randomized clinical trial

110. Ketogenic effects of medium chain triglycerides containing formula and its correlation to breath acetone in healthy volunteers: a randomized, double-blinded, placebo-controlled, single dose-response study.

Nakamura K, Hagihara K, Nagai N, Egashira R, Takeuchi M, Nakano M, Saito H, Moriguchi M, Tonari S, Fujii H, Miyake A, Omae Y, Ashida K · Frontiers in nutrition · 2023-09-27

Preclinical / mechanistic

111. Computational Analysis of Plasma Lipidomics from Mice Fed Standard Chow and Ketogenic Diet.

Seufert AL, Hickman JW, Choi J, Napier BA · Bio-protocol · 2023-09-20

Preclinical / mechanistic

112. Normal diet ameliorates obesity more safely and effectively than ketogenic diet does in high-fat diet-induced obesity mouse based on gut microbiota and lipid metabolism.

Dong Y, Song H, J Holmes A, Yan J, Ren C, Zhang Y, Zhao W, Yuan J, Cheng Y, Raubenheimer D, Cui Z · International journal of food sciences and nutrition · 2023-07-20

Randomized clinical trial

113. Short- and long-term effects of very low- and low-calorie ketogenic diets on metabolism and cardiometabolic risk factors: a narrative review.

Gaspa G, Naciu AM, DI Rosa C, Lattanzi G, Beato I, Micheli V, Turriziani C, Khazrai YM, Cesareo R · Minerva endocrinology · 2022-10-26

Preclinical / mechanistic

114. Ketogenic diet alters microglial morphology and changes the hippocampal lipidomic profile distinctively in stress susceptible versus resistant male mice upon repeated social defeat.

González Ibáñez F, Halvorson T, Sharma K, McKee C, Carrier M, Picard K, Vernoux N, Bisht K, Deslauriers J, Lalowski M, Tremblay MÈ · bioRxiv : the preprint server for biology · 2023-08-29

Case report / case series

115. Extreme Hypercholesterolemia Following a Ketogenic Diet: Exaggerated Response to an Increasingly Popular Diet.

Naveh N, Avidan Y, Zafrir B · Cureus · 2023-08-18

Preclinical / mechanistic

116. Does Ketogenic Diet Used in Pregnancy Affect the Nervous System Development in Offspring?─FTIR Microspectroscopy Study.

Rugiel M, Setkowicz-Janeczko Z, Kosiek W, Rauk Z, Kawon K, Chwiej J · ACS chemical neuroscience · 2023-07-20

Preclinical / mechanistic

117. Neuroprotective effect of a medium-chain triglyceride ketogenic diet on MPTP-induced Parkinson's disease mice: a combination of transcriptomics and metabolomics in the substantia nigra and fecal microbiome.

Zhang W, Chen S, Huang X, Tong H, Niu H, Lu L · Cell death discovery · 2023-07-17

Randomized clinical trial

118. Weight, insulin resistance, blood lipids, and diet quality changes associated with ketogenic and ultra low-fat dietary patterns: a secondary analysis of the DIETFITS randomized clinical trial.

Aronica L, Landry MJ, Rigdon J, Gardner CD · Frontiers in nutrition · 2023-07-12

Clinical trial / intervention

119. A ketogenic diet substantially reshapes the human metabolome.

Effinger D, Hirschberger S, Yoncheva P, Schmid A, Heine T, Newels P, Schütz B, Meng C, Gigl M, Kleigrewe K, Holdt LM, Teupser D, Kreth S · Clinical nutrition (Edinburgh, Scotland) · 2023-05-04

Clinical trial / intervention

120. Refueling the post COVID-19 brain: potential role of ketogenic medium chain triglyceride supplementation: an hypothesis.

Juby AG, Cunnane SC, Mager DR · Frontiers in nutrition · 2023-06-21

Other

121. Combination of triheptanoin with the ketogenic diet in Glucose transporter type 1 deficiency (G1D).

Avila A, Málaga I, Sirsi D, Kayani S, Primeaux S, Kathote GA, Jakkamsetti V, Kallem RR, Putnam WC, Park JY, Shinnar S, Pascual JM · Scientific reports · 2023-06-02

Case report / case series

122. Dramatic elevation of LDL cholesterol from ketogenic-dieting: A Case Series.

Schmidt T, Harmon DM, Kludtke E, Mickow A, Simha V, Kopecky S · American journal of preventive cardiology · 2023-04-06

Systematic review / meta-analysis

123. Effects of ketogenic diet on health outcomes: an umbrella review of meta-analyses of randomized clinical trials.

Patikorn C, Saidoung P, Pham T, Phisalprapa P, Lee YY, Varady KA, Veettil SK, Chaiyakunapruk N · BMC medicine · 2023-05-25

Clinical trial / intervention

124. Hepatokines, bile acids and ketone bodies are novel Hormones regulating energy homeostasis.

Garruti G, Baj J, Cignarelli A, Perrini S, Giorgino F · Frontiers in endocrinology · 2023-05-19

Observational human study

125. Comprehensive study of metabolic changes induced by a ketogenic diet therapy using GC/MS- and LC/MS-based metabolomics.

Akiyama M, Akiyama T, Saigusa D, Hishinuma E, Matsukawa N, Shibata T, Tsuchiya H, Mori A, Fujii Y, Mogami Y, Tokorodani C, Kuwahara K, Numata-Uematsu Y, Inoue K, Kobayashi K · Seizure · 2023-03-16

Other

126. Effect of a Ketogenic Medium Chain Triglyceride-Enriched Diet on the Fecal Microbiota in Canine Idiopathic Epilepsy: A Pilot Study.

García-Belenguer S, Grasa L, Palacio J, Moral J, Rosado B · Veterinary sciences · 2023-03-24

Case report / case series

127. 44-year-old man • elevated total cholesterol • chest pains • ketogenic diet • Dx?

Dickmann S, Carter D · The Journal of family practice · 2023-03-22

Clinical trial / intervention

128. Ketogenic Diet Combined with Moderate Aerobic Exercise Training Ameliorates White Adipose Tissue Mass, Serum Biomarkers, and Hepatic Lipid Metabolism in High-Fat Diet-Induced Obese Mice.

Yan J, Ren C, Dong Y, Wali JA, Song H, Zhang Y, Zhang H, Kou G, Raubenheimer D, Cui Z · Nutrients · 2023-01-03

Preclinical / mechanistic

129. Ketogenic diet containing medium-chain triglyceride ameliorates transcriptome disruption in skeletal muscles of rat models of duchenne muscular dystrophy.

Fujikura Y, Yamanouchi K, Sugihara H, Hatakeyama M, Abe T, Ato S, Oishi K · Biochemistry and biophysics reports · 2022-11-11

Systematic review / meta-analysis

130. Very low carbohydrate (ketogenic) diets in type 2 diabetes: A systematic review and meta-analysis of randomized controlled trials.

Parry-Strong A, Wright-McNaughton M, Weatherall M, Hall RM, Coppell KJ, Barthow C, Krebs JD · Diabetes, obesity & metabolism · 2022-09-05

Other

131. The ketogenic diet maintains insulin sensitivity and inhibits lipid accumulation in the liver.

King AN, Notaro NM · The Journal of physiology · 2022-10-06

Case report / case series

132. Short-term hyper-caloric high-fat feeding on a ketogenic diet can lower low-density lipoprotein cholesterol: the cholesterol drop experiment.

Feldman D, Huggins S, Norwitz NG · Current opinion in endocrinology, diabetes, and obesity · 2022-08-09

Systematic review / meta-analysis

133. Ketogenic therapy for Parkinson's disease: A systematic review and synthesis without meta-analysis of animal and human trials.

Grammatikopoulou MG, Tousinas G, Balodimou C, Anastasilakis DA, Gkiouras K, Dardiotis E, Evangeliou AE, Bogdanos DP, Goulis DG · Maturitas · 2022-06-09

Systematic review / meta-analysis

134. Effects of very low-carbohydrate ketogenic diet on lipid metabolism in patients with type II diabetes mellitus: a meta-analysis.

Li M, Yuan J · Nutricion hospitalaria · 2022-03-05

Case report / case series

135. Profound Elevation in LDL Cholesterol Level Following a Ketogenic Diet: A Case Series.

Crosier R, McPherson R · CJC open · 2022-06-09

Preclinical / mechanistic

136. A medium-chain triglyceride containing ketogenic diet exacerbates cardiomyopathy in a CRISPR/Cas9 gene-edited rat model with Duchenne muscular dystrophy.

Fujikura Y, Kimura K, Yamanouchi K, Sugihara H, Hatakeyama M, Zhuang H, Abe T, Daimon M, Morita H, Komuro I, Oishi K · Scientific reports · 2022-07-08

Clinical trial / intervention

137. Observation on the Efficacy of Ginkgo Ketone Ester Drop Pill in Improving Hypertension Combined with Carotid Atherosclerotic Plaque.

Zhang J, Ma Y · Emergency medicine international · 2022-06-30

Observational human study

138. The effect of low-carbohydrate ketogenic diet in the management of obesity compared with low caloric, low-fat diet.

Al Aamri KS, Alrawahi AH, Al Busaidi N, Al Githi MS, Al Jabri K, Al Balushi F, Ronquillo-Talara R, Al Balushi S, Waly M · Clinical nutrition ESPEN · 2022-02-24

Clinical trial / intervention

139. Effects of ketogenic diet on cognitive functions of mice fed high-fat-high-cholesterol diet.

Lin DT, Kao NJ, Cross TL, Lee WJ, Lin SH · The Journal of nutritional biochemistry · 2022-02-20

Review

140. Possible Nonneurological Health Benefits of Ketogenic Diet: Review of Scientific Reports over the Past Decade.

Daria Gołąbek K, Regulska-Ilow B · Journal of obesity · 2022-05-27

Preclinical / mechanistic

141. The Effect of Nutritional Ketosis on Aquaporin Expression in Apolipoprotein E-Deficient Mice: Potential Implications for Energy Homeostasis.

da Silva IV, Gullette S, Florindo C, Huang NK, Neuberger T, Ross AC, Soveral G, Castro R · Biomedicines · 2022-05-18

Observational human study

142. Ketonuria and Seizure Control in the Medium Chain Triglyceride and Classic Ketogenic Diets.

Lowe H, Keller AE, Tanzini E, Aimola S, Liu YMC, Zak M, Chan V, Kobayashi J, Donner EJ · The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques · 2021-06-02

Preclinical / mechanistic

143. Ketogenic Diet Consumption Inhibited Mitochondrial One-Carbon Metabolism.

Hsu FY, Liou JY, Tang FY, Sou NL, Peng JH, Chiang EI · International journal of molecular sciences · 2022-03-26

Randomized clinical trial

144. Ketogenic Effects of Multiple Doses of a Medium Chain Triglycerides Enriched Ketogenic Formula in Healthy Men under the Ketogenic Diet: A Randomized, Double-Blinded, Placebo-Controlled Study.

Nakamura K, Hagihara K, Nagai N, Egashira R, Takeuchi M, Nakano M, Saito H, Moriguchi M, Tonari S, Watanabe S, Miyake A, Ashida K · Nutrients · 2022-03-12

Randomized clinical trial

145. Examining the Efficacy of a Very-Low-Carbohydrate Ketogenic Diet on Cardiovascular Health in Adults with Mildly Elevated Low-Density Lipoprotein Cholesterol in an Open-Label Pilot Study.

Tzenios N, Lewis ED, Crowley DC, Chahine M, Evans M · Metabolic syndrome and related disorders · 2021-12-16

Preclinical / mechanistic

146. A comparative study of the effect of a gentle ketogenic diet containing medium-chain or long-chain triglycerides on chronic sleep deprivation-induced cognitive deficiency.

Wang X, Yang Y, Xiao A, Zhang N, Miao M, Wang Z, Han J, Wen M · Food & function · 2022-02-21

Preclinical / mechanistic

147. Is a Ketogenic Diet Superior to a High-Fat, High-Cholesterol Diet Regarding Testicular Function and Spermatogenesis?

Liu CY, Chang TC, Lin SH, Tsao CW · Frontiers in nutrition · 2022-02-10

Systematic review / meta-analysis

148. Effect of a very low-carbohydrate ketogenic diet vs recommended diets in patients with type 2 diabetes: a meta-analysis.

Rafiullah M, Musambil M, David SK · Nutrition reviews · 2021-08-03

Preclinical / mechanistic

149. Ketogenic diet ameliorates lipid dysregulation in type 2 diabetic mice by downregulating hepatic pescadillo 1.

Zhou J, Lu Y, Jia Y, Lu J, Jiang Z, Chen K · Molecular medicine (Cambridge, Mass.) · 2022-01-03

Case report / case series

150. Severe Hypertriglyceridemia-Induced Necrotizing Pancreatitis Associated With Ketogenic Diet in a Well-Controlled Patient With Type 2 Diabetes Mellitus.

Chan JT, Mude PJ, Canfield W, Makhija J, Yap JEL · Cureus · 2022-01-02

Other

151. Medium-chain Triglyceride Ketogenic Diet as a Treatment Strategy for Adult Super-refractory Status Epilepticus.

Dutta K, Satishchandra P, Borkotokey M · Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2022-02-03

Randomized clinical trial

152. Randomized Clinical Trial to Evaluate the Morphological Changes in the Adventitial Vasa Vasorum Density and Biological Markers of Endothelial Dysfunction in Subjects with Moderate Obesity Undergoing a Very Low-Calorie Ketogenic Diet.

Sánchez E, Santos MD, Nuñez-Garcia M, Bueno M, Sajoux I, Yeramian A, Lecube A · Nutrients · 2021-12-23

Observational human study

153. Efficacy and safety of ketogenic dietary theraphies in infancy. A single-center experience in 42 infants less than two years of age.

Ruiz-Herrero J, Cañedo-Villarroya E, Pérez-Sebastián I, Bernardino-Cuesta B, Pedrón-Giner C · Seizure · 2021-08-29

Preclinical / mechanistic

154. A Hypomethylating Ketogenic Diet in Apolipoprotein E-Deficient Mice: A Pilot Study on Vascular Effects and Specific Epigenetic Changes.

Castro R, Whalen CA, Gullette S, Mattie FJ, Florindo C, Heil SG, Huang NK, Neuberger T, Ross AC · Nutrients · 2021-10-13

Preclinical / mechanistic

155. Ketogenic diet aggravates kidney dysfunction by exacerbating metabolic disorders and inhibiting autophagy in spontaneously hypertensive rats.

Jia P, Huang B, You Y, Su H, Gao L · Biochemical and biophysical research communications · 2021-08-03

Other

156. The effect of ketogenic diet on serum lipid concentrations in children with medication resistant epilepsy.

Yılmaz Ü, Edizer S, Köse M, Akışin Z, Güzin Y, Pekuz S, Kırkgöz HH, Yavuz M, Ünalp A · Seizure · 2021-06-10

Preclinical / mechanistic

157. Ketogenic diet with medium-chain triglycerides restores skeletal muscle function and pathology in a rat model of Duchenne muscular dystrophy.

Fujikura Y, Sugihara H, Hatakeyama M, Oishi K, Yamanouchi K · FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2021-07-16

Clinical trial / intervention

158. Effects of low-carbohydrate diet and ketogenic diet on glucose and lipid metabolism in type 2 diabetic mice.

Yang Z, Mi J, Wang Y, Xue L, Liu J, Fan M, Zhang D, Wang L, Qian H, Li Y · Nutrition (Burbank, Los Angeles County, Calif.) · 2021-03-04

Systematic review / meta-analysis

159. Effect of a Ketogenic Diet on the Nutritional Parameters of Obese Patients: A Systematic Review and Meta-Analysis.

López-Espinoza MÁ, Chacón-Moscoso S, Sanduvete-Chaves S, Ortega-Maureira MJ, Barrientos-Bravo T · Nutrients · 2021-08-25

Review

160. Ketogenic diet for depression: A potential dietary regimen to maintain euthymia?

Włodarczyk A, Cubała WJ, Stawicki M · Progress in neuro-psychopharmacology & biological psychiatry · 2021-01-23

Clinical trial / intervention

161. The possibility of use of the ketogenic diet and medium chain triglycerides supplementation in the support therapy of Alzheimer disease.

Włodarek D · Current opinion in clinical nutrition and metabolic care · 2021-03-21

Clinical trial / intervention

162. The Feasibility and Tolerability of Medium Chain Triglycerides in Women with a Catamenial Seizure Pattern on the Modified Atkins Diet.

Felton EA, Henry-Barron BJ, Jan AK, Shegelman A, Faltersack K, Vizthum D, Cervenka MC · Nutrients · 2021-06-30

Randomized clinical trial

163. An fMRI Investigation into the Effects of Ketogenic Medium-Chain Triglycerides on Cognitive Function in Elderly Adults: A Pilot Study.

Yomogida Y, Matsuo J, Ishida I, Ota M, Nakamura K, Ashida K, Kunugi H · Nutrients · 2021-06-22

Other

164. Successful implementation of classical ketogenic dietary therapy in a patient with Niemann-Pick disease type C.

Höller A, Albrecht U, Baumgartner Sigl S, Zöggeler T, Ramoser G, Bernar B, Karall D, Scholl-Bürgi S · Molecular genetics and metabolism reports · 2021-02-05

Other

165. Hypercholesterolemia exacerbated by a ketogenic diet.

Khovidhunkit W, Hanvivadhanakul P · Journal of clinical lipidology · 2021-05-07

Clinical trial / intervention

166. Effect of a Free-Living Ketogenic Diet on Feasibility, Satiety, Body Composition, and Metabolic Health in Women: The Grading Level of Optimal Carbohydrate for Women (GLOW) Study.

Saenz C, Hooper S, Orange T, Knight A, Barragan M, Lynch T, Remenapp A, Coyle K, Winters C, Hausenblas H · Journal of the American College of Nutrition · 2021-03-11

Randomized clinical trial

167. Effects of calorie restricted low carbohydrate high fat ketogenic vs. non-ketogenic diet on strength, body-composition, hormonal and lipid profile in trained middle-aged men.

Vidić V, Ilić V, Toskić L, Janković N, Ugarković D · Clinical nutrition (Edinburgh, Scotland) · 2021-02-26

Preclinical / mechanistic

168. Ketogenic Diets Induced Glucose Intolerance and Lipid Accumulation in Mice with Alterations in Gut Microbiota and Metabolites.

Li Y, Yang X, Zhang J, Jiang T, Zhang Z, Wang Z, Gong M, Zhao L, Zhang C · mBio · 2021-03-30

Preclinical / mechanistic

169. Octanoic acid a major component of widely consumed medium-chain triglyceride ketogenic diet is detrimental to bone.

Jain S, Rai R, Singh D, Vohora D · Scientific reports · 2021-03-26

Preclinical / mechanistic

170. Ketogenic Diet Enhances the Cholesterol Accumulation in Liver and Augments the Severity of CCl4 and TAA-Induced Liver Fibrosis in Mice.

Liao YJ, Wang YH, Wu CY, Hsu FY, Chien CY, Lee YC · International journal of molecular sciences · 2021-03-13

Systematic review / meta-analysis

171. Influences of Ketogenic Diet on Body Fat Percentage, Respiratory Exchange Rate, and Total Cholesterol in Athletes: A Systematic Review and Meta-Analysis.

Lee HS, Lee J · International journal of environmental research and public health · 2021-03-12

Other

172. Differential ketogenic diet-induced shift in CSF lipid/carbohydrate metabolome of pediatric epilepsy patients with optimal vs. no anticonvulsant response: a pilot study.

Masino SA, Ruskin DN, Freedgood NR, Lindefeldt M, Dahlin M · Nutrition & metabolism · 2021-03-01

Preclinical / mechanistic

173. Transcriptome analysis of two structurally related flavonoids; Apigenin and Chrysin revealed hypocholesterolemic and ketogenic effects in mouse embryonic fibroblasts.

Puthanveetil P, Kong X, Bräse S, Voros G, Peer WA · European journal of pharmacology · 2020-12-23

Systematic review / meta-analysis

174. Effects of Combined Exercise and Low Carbohydrate Ketogenic Diet Interventions on Waist Circumference and Triglycerides in Overweight and Obese Individuals: A Systematic Review and Meta-Analysis.

Lee HS, Lee J · International journal of environmental research and public health · 2021-01-19

Preclinical / mechanistic

175. The Safety of Very-long-term Intake of a Ketogenic Diet Containing Medium-chain Triacylglycerols.

Fukazawa A, Karasawa T, Yokota Y, Kondo S, Aoyama T, Terada S · Journal of oleo science · 2021-07-01

Case report / case series

176. Ketogenic diets, not for everyone.

Goldberg IJ, Ibrahim N, Bredefeld C, Foo S, Lim V, Gutman D, Huggins LA, Hegele RA · Journal of clinical lipidology · 2020-10-31

Preclinical / mechanistic

177. The Effects of a Ketogenic Medium-Chain Triglyceride Diet on the Feces in Dogs With Idiopathic Epilepsy.

Pilla R, Law TH, Pan Y, Zanghi BM, Li Q, Want EJ, Lidbury JA, Steiner JM, Suchodolski JS, Volk HA · Frontiers in veterinary science · 2020-12-22

Preclinical / mechanistic

178. Ketogenic Diet: Impact on Cellular Lipids in Hippocampal Murine Neurons.

Dabke P, Brogden G, Naim HY, Das AM · Nutrients · 2020-12-18

Preclinical / mechanistic

179. Biochemical and histomorphological changes in testosterone propionate-induced benign prostatic hyperplasia in male Wistar rats treated with ketogenic diet.

Kayode OT, Owolabi AV, Kayode AAA · Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2020-10-28

Clinical trial / intervention

180. A ketogenic diet combined with exercise alters mitochondrial function in human skeletal muscle while improving metabolic health.

Miller VJ, LaFountain RA, Barnhart E, Sapper TS, Short J, Arnold WD, Hyde PN, Crabtree CD, Kackley ML, Kraemer WJ, Villamena FA, Volek JS · American journal of physiology. Endocrinology and metabolism · 2020-09-28

Review

181. Emerging Therapeutic Promise of Ketogenic Diet to Attenuate Neuropathological Alterations in Alzheimer's Disease.

Uddin MS, Kabir MT, Tewari D, Al Mamun A, Barreto GE, Bungau SG, Bin-Jumah MN, Abdel-Daim MM, Ashraf GM · Molecular neurobiology · 2020-08-20

Clinical trial / intervention

182. [The impact on metabolic and reproductive diseases of low-carbohydrate and ketogenic diets].

Moreno-Sepúlveda J, Capponi M · Revista medica de Chile · 2019-08-22

Clinical trial / intervention

183. Very low calorie ketogenic diets in overweight and obesity treatment: Effects on anthropometric parameters, body composition, satiety, lipid profile and microbiota.

Di Rosa C, Lattanzi G, Taylor SF, Manfrini S, Khazrai YM · Obesity research & clinical practice · 2020-09-09

Observational human study

184. Longitudinal changes in insulin resistance in children with epilepsy on ketogenic diet: Prevalence and risk factors.

Kong J, Nam SO, Ko A, Byun SY, Lim TJ, Kim YM, Yeon GM, Cho JW, Lee YJ · Epilepsy & behavior : E&B · 2020-08-22

Case report / case series

185. Reversal of severe hypertriglyceridemia with intermittent fasting and a very-low-carbohydrate ketogenic diet: a case series.

Das S, McCreary J, Shamim S, Kalayjian T · Current opinion in endocrinology, diabetes, and obesity · 2020-08-03

Review

186. Adenosine and Ketogenic Treatments.

Ruskin DN, Kawamura M, Masino SA · Journal of caffeine and adenosine research · 2020-09-16

Case report / case series

187. Significant Impact of the Ketogenic Diet on Low-Density Lipoprotein Cholesterol Levels.

Salas Noain J, Minupuri A, Kulkarni A, Zheng S · Cureus · 2020-07-27

Preclinical / mechanistic

188. Ketogenic diet improves and restores redox status and biochemical indices in monosodium glutamate-induced rat testicular toxicity.

Kayode OT, Rotimi DE, Olaolu TD, Adeyemi OS · Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2020-05-17

Case report / case series

189. A Standard Lipid Panel Is Insufficient for the Care of a Patient on a High-Fat, Low-Carbohydrate Ketogenic Diet.

Norwitz NG, Loh V · Frontiers in medicine · 2020-04-15

Other

190. Transition from ketogenic diet to triheptanoin in patients with GLUT1 deficiency syndrome.

Hainque E, Meneret A, Gras D, Atencio M, Luton MP, Barbier M, De Saint Martin A, Billette de Villemeur T, Ottolenghi C, Roze E, Mochel F · Journal of neurology, neurosurgery, and psychiatry · 2019-11-06

Systematic review / meta-analysis

191. Efficacy and safety of very low calorie ketogenic diet (VLCKD) in patients with overweight and obesity: A systematic review and meta-analysis.

Castellana M, Conte E, Cignarelli A, Perrini S, Giustina A, Giovanella L, Giorgino F, Trimboli P · Reviews in endocrine & metabolic disorders · 2019-11-11

Randomized clinical trial

192. Cardiometabolic risk and effectiveness of the modified Atkins Ketogenic Diet for adult patients with pharmacoresistant epilepsies in a middle-income country.

de Souza Neves G, Dos Santos Lunardi M, Papini Gabiatti M, Kurrle Rieger Venske D, Ribeiro LC, Lin K, Dubois Moreira J · Epilepsy research · 2020-01-16

Case report / case series

193. Ketogenic Diet-induced Elevated Cholesterol, Elevated Liver Enzymes and Potential Non-alcoholic Fatty Liver Disease.

Anekwe CV, Chandrasekaran P, Stanford FC · Cureus · 2020-01-08

Randomized clinical trial

194. Metabolic and Immunological Effects of Intermittent Fasting on a Ketogenic Diet Containing Medium-Chain Triglycerides in Healthy Dogs.

Leung YB, Cave NJ, Heiser A, Edwards PJB, Godfrey AJR, Wester T · Frontiers in veterinary science · 2020-01-08

Preclinical / mechanistic

195. Magnesium Supplementation did not affect the Antiseizure Property of Ketogenic Diet but Reduced Lipid Dysmetabolism.

Sanya EO, Adeyanju OA, Olarinoye JK, Bello H, Alaofin WA, Wahab KW, Soladoye AA · West African journal of medicine · 2020-02-08

Randomized clinical trial

196. The ketogenic diet: Pros and cons.

O'Neill B, Raggi P · Atherosclerosis · 2019-11-28

Randomized clinical trial

197. A Ketogenic Diet Is Acceptable in Women with Ovarian and Endometrial Cancer and Has No Adverse Effects on Blood Lipids: A Randomized, Controlled Trial.

Cohen CW, Fontaine KR, Arend RC, Gower BA · Nutrition and cancer · 2019-07-27

Preclinical / mechanistic

198. Ketogenic diet in combination with voluntary exercise impacts markers of hepatic metabolism and oxidative stress in male and female Wistar rats.

Moore MP, Cunningham RP, Kelty TJ, Boccardi LR, Nguyen NY, Booth FW, Rector RS · Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme · 2019-05-22

Preclinical / mechanistic

199. A low-carbohydrate ketogenic diet induces the expression of very-low-density lipoprotein receptor in liver and affects its associated metabolic abnormalities.

Okuda T · NPJ science of food · 2019-12-02

Observational human study

200. Medium-chain triglyceride ketogenic diet is effective for treatment of an adult with super-refractory status epilepticus: a case report and literature review.

Prasoppokakorn T, Jirasakuldej S, Lakananurak N · European journal of clinical nutrition · 2019-07-17

Preclinical / mechanistic

201. Ketone body receptor GPR43 regulates lipid metabolism under ketogenic conditions.

Miyamoto J, Ohue-Kitano R, Mukouyama H, Nishida A, Watanabe K, Igarashi M, Irie J, Tsujimoto G, Satoh-Asahara N, Itoh H, Kimura I · Proceedings of the National Academy of Sciences of the United States of America · 2019-11-04

Review

202. Ketogenic Diet: A New Light Shining on Old but Gold Biochemistry.

Longo R, Peri C, Cricrì D, Coppi L, Caruso D, Mitro N, De Fabiani E, Crestani M · Nutrients · 2019-10-17

Systematic review / meta-analysis

203. Review of current evidence and clinical recommendations on the effects of low-carbohydrate and very-low-carbohydrate (including ketogenic) diets for the management of body weight and other cardiometabolic risk factors: A scientific statement from the National Lipid Association Nutrition and Lifestyle Task Force.

Kirkpatrick CF, Bolick JP, Kris-Etherton PM, Sikand G, Aspry KE, Soffer DE, Willard KE, Maki KC · Journal of clinical lipidology · 2019-09-13

Clinical trial / intervention

204. Improvement in Glycemic and Lipid Profiles in Type 2 Diabetics with a 90-Day Ketogenic Diet.

Walton CM, Perry K, Hart RH, Berry SL, Bikman BT · Journal of diabetes research · 2019-08-14

Case report / case series

205. Successful Management of Ketogenic Parenteral Nutrition: A Pediatric Case Study.

Lowe H, Segal S, Mouzaki M, Langos V, Dlamini N · JPEN. Journal of parenteral and enteral nutrition · 2018-12-20

Clinical trial / intervention

206. Ketogenic diet ameliorates axonal defects and promotes myelination in Pelizaeus-Merzbacher disease.

Stumpf SK, Berghoff SA, Trevisiol A, Spieth L, Düking T, Schneider LV, Schlaphoff L, Dreha-Kulaczewski S, Bley A, Burfeind D, Kusch K, Mitkovski M, Ruhwedel T, Guder P, Röhse H, Denecke J, Gärtner J, Möbius W, Nave KA, Saher G · Acta neuropathologica · 2019-03-27

Other

207. Glucose and Lipid Homeostasis and Inflammation in Humans Following an Isocaloric Ketogenic Diet.

Rosenbaum M, Hall KD, Guo J, Ravussin E, Mayer LS, Reitman ML, Smith SR, Walsh BT, Leibel RL · Obesity (Silver Spring, Md.) · 2019-05-08

Other

208. [Effects of ketogenic diet on lipid metabolism in children with intractable epilepsy].

Chen H, Chen YH, Liu L, Wang Y · Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2019-05-21

Review

209. The ketogenic diet as a potential treatment and prevention strategy for Alzheimer's disease.

Broom GM, Shaw IC, Rucklidge JJ · Nutrition (Burbank, Los Angeles County, Calif.) · 2018-10-10

Clinical trial / intervention

210. Ketogenic diet rescues cognition in ApoE4+ patient with mild Alzheimer's disease: A case study.

Morrill SJ, Gibas KJ · Diabetes & metabolic syndrome · 2019-01-24

Randomized clinical trial

211. Two-Week Exclusive Supplementation of Modified Ketogenic Nutrition Drink Reserves Lean Body Mass and Improves Blood Lipid Profile in Obese Adults: A Randomized Clinical Trial.

Choi HR, Kim J, Lim H, Park YK · Nutrients · 2018-12-03

Clinical trial / intervention

212. Metabolic perturbations associated with the consumption of a ketogenic medium-chain TAG diet in dogs with idiopathic epilepsy.

Law TH, Volk HA, Pan Y, Zanghi B, Want EJ · The British journal of nutrition · 2018-07-13

Other

213. Breath profiles of children on ketogenic therapy.

Ruzsányi V, Péter Kalapos M, Schmidl C, Karall D, Scholl-Bürgi S, Baumann M · Journal of breath research · 2018-06-08

Randomized clinical trial

214. The Effect of Medium Chain Triglycerides on Time to Nutritional Ketosis and Symptoms of Keto-Induction in Healthy Adults: A Randomised Controlled Clinical Trial.

D C Harvey CJ, Schofield GM, Williden M, McQuillan JA · Journal of nutrition and metabolism · 2018-05-22

Clinical trial / intervention

215. A modified ketogenic gluten-free diet with MCT improves behavior in children with autism spectrum disorder.

Lee RWY, Corley MJ, Pang A, Arakaki G, Abbott L, Nishimoto M, Miyamoto R, Lee E, Yamamoto S, Maunakea AK, Lum-Jones A, Wong M · Physiology & behavior · 2018-02-05

Review

216. Internist, anesthesiologist and surgeon use of ketogenic diet.

Cenci L, Paoli A, Omar HR, Dalvi P, Camporesi EM, Mangar D, Quartesan S, Fiorito A, Bosco G · Minerva gastroenterologica e dietologica · 2018-01-09

Clinical trial / intervention

217. Ketogenic Medium Chain Triglycerides Increase Brain Energy Metabolism in Alzheimer's Disease.

Croteau E, Castellano CA, Richard MA, Fortier M, Nugent S, Lepage M, Duchesne S, Whittingstall K, Turcotte ÉE, Bocti C, Fülöp T, Cunnane SC · Journal of Alzheimer's disease : JAD · 2018-06-20

Other

218. Efficacy of a ketogenic diet with concomitant intranasal perillyl alcohol as a novel strategy for the therapy of recurrent glioblastoma.

Santos JG, Da Cruz WMS, Schönthal AH, Salazar MD, Fontes CAP, Quirico-Santos T, Da Fonseca CO · Oncology letters · 2017-11-08

Preclinical / mechanistic

219. A ketogenic diet supplemented with medium-chain triglycerides enhances the anti-tumor and anti-angiogenic efficacy of chemotherapy on neuroblastoma xenografts in a CD1-nu mouse model.

Aminzadeh-Gohari S, Feichtinger RG, Vidali S, Locker F, Rutherford T, O'Donnel M, Stöger-Kleiber A, Mayr JA, Sperl W, Kofler B · Oncotarget · 2017-08-08

Other

220. Neuronal decanoic acid oxidation is markedly lower than that of octanoic acid: A mechanistic insight into the medium-chain triglyceride ketogenic diet.

Khabbush A, Orford M, Tsai YC, Rutherford T, O'Donnell M, Eaton S, Heales SJR · Epilepsia · 2017-07-06

Review

221. Ketogenic diet and testosterone increase: Is the increased cholesterol intake responsible? To what extent and under what circumstances can there be benefits?

Santos HO · Hormones (Athens, Greece) · 2017-09-30

Other

222. Emulsification Increases the Acute Ketogenic Effect and Bioavailability of Medium-Chain Triglycerides in Humans: Protein, Carbohydrate, and Fat Metabolism.

Courchesne-Loyer A, Lowry CM, St-Pierre V, Vandenberghe C, Fortier M, Castellano CA, Wagner JR, Cunnane SC · Current developments in nutrition · 2017-06-21

Clinical trial / intervention

223. The efficacy of the ketogenic diet in infants and young children with refractory epilepsies using a formula-based powder.

Ashrafi MR, Hosseini SA, Zamani GR, Mohammadi M, Tavassoli A, Badv RS, Heidari M, Karimi P, Malamiri RA · Acta neurologica Belgica · 2016-12-07

Other

224. Impact of a 6-week non-energy-restricted ketogenic diet on physical fitness, body composition and biochemical parameters in healthy adults.

Urbain P, Strom L, Morawski L, Wehrle A, Deibert P, Bertz H · Nutrition & metabolism · 2017-02-20

Observational human study

225. Is ketogenic diet treatment hepatotoxic for children with intractable epilepsy?

Arslan N, Guzel O, Kose E, Yılmaz U, Kuyum P, Aksoy B, Çalık T · Seizure · 2016-11-13

Clinical trial / intervention

226. The effects of classic ketogenic diet on serum lipid profile in children with refractory seizures.

Zamani GR, Mohammadi M, Ashrafi MR, Karimi P, Mahmoudi M, Badv RS, Tavassoli AR, Azizi Malamiri R · Acta neurologica Belgica · 2016-01-20

Randomized clinical trial

227. Effect of DHA supplementation in a very low-calorie ketogenic diet in the treatment of obesity: a randomized clinical trial.

de Luis D, Domingo JC, Izaola O, Casanueva FF, Bellido D, Sajoux I · Endocrine · 2016-04-27

Case report / case series

228. Severe Hypertriglyceridemia in Glut1D on Ketogenic Diet.

Klepper J, Leiendecker B, Heussinger N, Lausch E, Bosch F · Neuropediatrics · 2016-02-22

Other

229. The effect of olive oil-based ketogenic diet on serum lipid levels in epileptic children.

Güzel O, Yılmaz U, Uysal U, Arslan N · Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2015-12-23

Preclinical / mechanistic

230. Effects of exogenous ketone supplementation on blood ketone, glucose, triglyceride, and lipoprotein levels in Sprague-Dawley rats.

Kesl SL, Poff AM, Ward NP, Fiorelli TN, Ari C, Van Putten AJ, Sherwood JW, Arnold P, D'Agostino DP · Nutrition & metabolism · 2016-02-04

Other

231. Effectiveness of Medium Chain Triglyceride Ketogenic Diet in Thai Children with Intractable Epilepsy.

Chomtho K, Suteerojntrakool O, Chomtho S · Journal of the Medical Association of Thailand = Chotmaihet thangphaet · 2016-06-03

Other

232. Diet and identity: being a good parent in the face of contradictions presented by the ketogenic diet.

Webster M, Gabe J · Sociology of health & illness · 2015-09-18

Observational human study

233. The impact of the modified Atkins diet on lipid profiles in adults with epilepsy.

Cervenka MC, Patton K, Eloyan A, Henry B, Kossoff EH · Nutritional neuroscience · 2014-11-10

Preclinical / mechanistic

234. White Matter Lipids as a Ketogenic Fuel Supply in Aging Female Brain: Implications for Alzheimer's Disease.

Klosinski LP, Yao J, Yin F, Fonteh AN, Harrington MG, Christensen TA, Trushina E, Brinton RD · EBioMedicine · 2015-11-03

Other

235. Ketogenic response to cotreatment with bezafibrate and medium chain triacylglycerols in healthy humans.

Courchesne-Loyer A, St-Pierre V, Hennebelle M, Castellano CA, Fortier M, Tessier D, Cunnane SC · Nutrition (Burbank, Los Angeles County, Calif.) · 2015-06-06

Preclinical / mechanistic

236. Neurobehavioral Deficits in a Rat Model of Recurrent Neonatal Seizures Are Prevented by a Ketogenic Diet and Correlate with Hippocampal Zinc/Lipid Transporter Signals.

Tian T, Ni H, Sun BL · Biological trace element research · 2015-03-17

Preclinical / mechanistic

237. HEPATIC FATTY ACID PROFILE OF RATS FED A TRIHEPTANOIN-BASED KETOGENIC DIET.

Vieira de Melo IS, Da Rocha Ataide T, Lima de Oliveira S, Bezerra Bueno N, Duarte de Freitas J, Goulart Sant'Ana AE · Nutricion hospitalaria · 2015-07-01

Clinical trial / intervention

238. Growth of human colon cancer cells in nude mice is delayed by ketogenic diet with or without omega-3 fatty acids and medium-chain triglycerides.

Hao GW, Chen YS, He DM, Wang HY, Wu GH, Zhang B · Asian Pacific journal of cancer prevention : APJCP · 2015-03-17

Other

239. Effects of ketogenic diet on vascular function.

Kapetanakis M, Liuba P, Odermarsky M, Lundgren J, Hallböök T · European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society · 2014-03-25

Preclinical / mechanistic

240. Influence of a ketogenic diet, fish-oil, and calorie restriction on plasma metabolites and lipids in C57BL/6J mice.

Meidenbauer JJ, Ta N, Seyfried TN · Nutrition & metabolism · 2014-05-22

Other

241. The impact of the ketogenic diet on arterial morphology and endothelial function in children and young adults with epilepsy: a case-control study.

Coppola G, Natale F, Torino A, Capasso R, D'Aniello A, Pironti E, Santoro E, Calabrò R, Verrotti A · Seizure · 2013-12-12

Preclinical / mechanistic

242. Long-term ketogenic diet causes glucose intolerance and reduced β- and α-cell mass but no weight loss in mice.

Ellenbroek JH, van Dijck L, Töns HA, Rabelink TJ, Carlotti F, Ballieux BE, de Koning EJ · American journal of physiology. Endocrinology and metabolism · 2014-01-07

Preclinical / mechanistic

243. Pantethine treatment is effective in recovering the disease phenotype induced by ketogenic diet in a pantothenate kinase-associated neurodegeneration mouse model.

Brunetti D, Dusi S, Giordano C, Lamperti C, Morbin M, Fugnanesi V, Marchet S, Fagiolari G, Sibon O, Moggio M, d'Amati G, Tiranti V · Brain : a journal of neurology · 2013-12-06

Preclinical / mechanistic

244. A gestational ketogenic diet alters maternal metabolic status as well as offspring physiological growth and brain structure in the neonatal mouse.

Sussman D, Ellegood J, Henkelman M · BMC pregnancy and childbirth · 2013-10-29

Clinical trial / intervention

245. Role of choline deficiency in the Fatty liver phenotype of mice fed a low protein, very low carbohydrate ketogenic diet.

Schugar RC, Huang X, Moll AR, Brunt EM, Crawford PA · PloS one · 2013-08-29

Observational human study

246. Can children with hyperlipidemia receive ketogenic diet for medication-resistant epilepsy?

Liu YM, Lowe H, Zak MM, Kobayashi J, Chan VW, Donner EJ · Journal of child neurology · 2013-02-20

Case report / case series

247. Lipoid pneumonia--a case of refractory pneumonia in a child treated with ketogenic diet.

Buda P, Wieteska-Klimczak A, Własienko A, Mazur A, Ziołkowski J, Jaworska J, Kościesza A, Dunin-Wąsowicz D, Książyk J · Pneumonologia i alergologia polska · 2013-08-22

Case report / case series

248. Case report of pyruvate dehydrogenase deficiency with unusual increase of fats during ketogenic diet treatment.

Di Pisa V, Cecconi I, Gentile V, Di Pietro E, Marchiani V, Verrotti A, Franzoni E · Journal of child neurology · 2012-02-28

Clinical trial / intervention

249. Effect of low-calorie versus low-carbohydrate ketogenic diet in type 2 diabetes.

Hussain TA, Mathew TC, Dashti AA, Asfar S, Al-Zaid N, Dashti HM · Nutrition (Burbank, Los Angeles County, Calif.) · 2012-06-05

Other

250. Transcript profiling of the ruminant liver indicates a unique program of transcriptional regulation of ketogenic enzymes during food restriction.

Doelman J, Cao H, Purdie NG, Kim JJ, Swanson KC, Osborne VR, Tey J, Ali A, Feng Z, Karrow NA, Cant JP · Comparative biochemistry and physiology. Part D, Genomics & proteomics · 2012-06-15

Review

251. Alternative diets to the classical ketogenic diet--can we be more liberal?

Miranda MJ, Turner Z, Magrath G · Epilepsy research · 2012-07-06

Clinical trial / intervention

252. Long-term follow-up of children treated with the modified Atkins diet.

Chen W, Kossoff EH · Journal of child neurology · 2012-04-24

Randomized clinical trial

253. The effect of the classical and medium chain triglyceride ketogenic diet on vitamin and mineral levels.

Christodoulides SS, Neal EG, Fitzsimmons G, Chaffe HM, Jeanes YM, Aitkenhead H, Cross JH · Journal of human nutrition and dietetics : the official journal of the British Dietetic Association · 2011-05-27

Case report / case series

254. Successful treatment of severe cardiomyopathy in glycogen storage disease type III With D,L-3-hydroxybutyrate, ketogenic and high-protein diet.

Valayannopoulos V, Bajolle F, Arnoux JB, Dubois S, Sannier N, Baussan C, Petit F, Labrune P, Rabier D, Ottolenghi C, Vassault A, Broissand C, Bonnet D, de Lonlay P · Pediatric research · 2011-08-23

Guideline / consensus

255. A pilot study of the Spanish Ketogenic Mediterranean Diet: an effective therapy for the metabolic syndrome.

Pérez-Guisado J, Muñoz-Serrano A · Journal of medicinal food · 2011-05-25

Preclinical / mechanistic

256. PPARα deficiency augments a ketogenic diet-induced circadian PAI-1 expression possibly through PPARγ activation in the liver.

Oishi K, Uchida D, Ohkura N, Horie S · Biochemical and biophysical research communications · 2010-09-18

Other

257. Long-term outcomes of children treated with the ketogenic diet in the past.

Patel A, Pyzik PL, Turner Z, Rubenstein JE, Kossoff EH · Epilepsia · 2010-02-01

Other

258. Low-carbohydrate ketogenic diet and the combination of orlistat with a low-fat diet lead to comparable improvements in weight and blood lipids, but LCKD more beneficial for blood pressure.

Gardner CD · Evidence-based medicine · 2010-06-05

Preclinical / mechanistic

259. Restricted ketogenic diet enhances the therapeutic action of N-butyldeoxynojirimycin towards brain GM2 accumulation in adult Sandhoff disease mice.

Denny CA, Heinecke KA, Kim YP, Baek RC, Loh KS, Butters TD, Bronson RT, Platt FM, Seyfried TN · Journal of neurochemistry · 2010-04-03

Preclinical / mechanistic

260. Ketogenic diet slows down mitochondrial myopathy progression in mice.

Ahola-Erkkilä S, Carroll CJ, Peltola-Mjösund K, Tulkki V, Mattila I, Seppänen-Laakso T, Oresic M, Tyynismaa H, Suomalainen A · Human molecular genetics · 2010-02-17

Clinical trial / intervention

261. Resistance training in overweight women on a ketogenic diet conserved lean body mass while reducing body fat.

Jabekk PT, Moe IA, Meen HD, Tomten SE, Høstmark AT · Nutrition & metabolism · 2010-03-02

Preclinical / mechanistic

262. A ketogenic diet increases succinic dehydrogenase activity in aging cardiomyocytes.

Balietti M, Fattoretti P, Giorgetti B, Casoli T, Di Stefano G, Solazzi M, Platano D, Aicardi G, Bertoni-Freddari C · Annals of the New York Academy of Sciences · 2009-09-03

Clinical trial / intervention

263. Metabolic response to a ketogenic breakfast in the healthy elderly.

Freemantle E, Vandal M, Tremblay Mercier J, Plourde M, Poirier J, Cunnane SC · The journal of nutrition, health & aging · 2009-03-21

Preclinical / mechanistic

264. Ketogenic diet-fed rats have increased fat mass and phosphoenolpyruvate carboxykinase activity.

Ribeiro LC, Chittó AL, Müller AP, Rocha JK, Castro da Silva M, Quincozes-Santos A, Nardin P, Rotta LN, Ziegler DR, Gonçalves CA, Da Silva RS, Perry ML, Gottfried C · Molecular nutrition & food research · 2008-07-26

Other

265. Growth of children on classical and medium-chain triglyceride ketogenic diets.

Neal EG, Chaffe HM, Edwards N, Lawson MS, Schwartz RH, Cross JH · Pediatrics · 2008-08-05

Randomized clinical trial

266. Management and risk factors for dyslipidemia with the ketogenic diet.

Nizamuddin J, Turner Z, Rubenstein JE, Pyzik PL, Kossoff EH · Journal of child neurology · 2008-07-29

Preclinical / mechanistic

267. Ketogenic diets cause opposing changes in synaptic morphology in CA1 hippocampus and dentate gyrus of late-adult rats.

Balietti M, Giorgetti B, Fattoretti P, Grossi Y, Di Stefano G, Casoli T, Platano D, Solazzi M, Orlando F, Aicardi G, Bertoni-Freddari C · Rejuvenation research · 2008-07-03

Preclinical / mechanistic

268. Effects of short-term and long-term treatment with medium- and long-chain triglycerides ketogenic diet on cortical spreading depression in young rats.

de Almeida Rabello Oliveira M, da Rocha Ataíde T, de Oliveira SL, de Melo Lucena AL, de Lira CE, Soares AA, de Almeida CB, Ximenes-da-Silva A · Neuroscience letters · 2008-01-19

Review

269. Ketogenic diets for weight loss: A review of their principles, safety and efficacy.

Sumithran P, Proietto J · Obesity research & clinical practice · 2007-06-25

Clinical trial / intervention

270. A prospective study of the modified Atkins diet for intractable epilepsy in adults.

Kossoff EH, Rowley H, Sinha SR, Vining EP · Epilepsia · 2007-10-05

Other

271. Effect of short-term ketogenic diet on redox status of human blood.

Nazarewicz RR, Ziolkowski W, Vaccaro PS, Ghafourifar P · Rejuvenation research · 2007-08-01

Other

272. Commentary on the effects of a ketogenic diet enriched with omega-3 polyunsaturated fatty acids on plasma phospholipid fatty acid profile in children with drug-resistant epilepsy.

Taha AY, McIntyre Burnham W · Epilepsy research · 2007-09-11

Clinical trial / intervention

273. Beneficial effects of ketogenic diet in obese diabetic subjects.

Dashti HM, Mathew TC, Khadada M, Al-Mousawi M, Talib H, Asfar SK, Behbahani AI, Al-Zaid NS · Molecular and cellular biochemistry · 2007-04-20

Randomized clinical trial

274. Efficacy and tolerability of the ketogenic diet according to lipid:nonlipid ratios--comparison of 3:1 with 4:1 diet.

Seo JH, Lee YM, Lee JS, Kang HC, Kim HD · Epilepsia · 2007-03-26

Other

275. Plasma phospholipid fatty acids are influenced by a ketogenic diet enriched with n-3 fatty acids in children with epilepsy.

Dahlin M, Hjelte L, Nilsson S, Amark P · Epilepsy research · 2006-12-05

Review

276. [The role of the ketogenic diet in the management of epilepsy].

Starbała A, Bawa SH · Roczniki Panstwowego Zakladu Higieny · 2007-08-23

Observational human study

277. Long-term use of the ketogenic diet in the treatment of epilepsy.

Groesbeck DK, Bluml RM, Kossoff EH · Developmental medicine and child neurology · 2006-05-08

Preclinical / mechanistic

278. Markedly raised intake of saturated and monounsaturated fatty acids in rats on a high-fat ketogenic diet does not inhibit carbon recycling of 13C-alpha-linolenate.

Taha AY, Ryan MA, Cunnane SC · Lipids · 2006-12-22

Randomized clinical trial

279. Effect of a low-carbohydrate, ketogenic diet program compared to a low-fat diet on fasting lipoprotein subclasses.

Westman EC, Yancy WS, Olsen MK, Dudley T, Guyton JR · International journal of cardiology · 2005-11-16

Clinical trial / intervention

280. Long term effects of ketogenic diet in obese subjects with high cholesterol level.

Dashti HM, Al-Zaid NS, Mathew TC, Al-Mousawi M, Talib H, Asfar SK, Behbahani AI · Molecular and cellular biochemistry · 2006-04-21

Randomized clinical trial

281. Ketogenic low-carbohydrate diets have no metabolic advantage over nonketogenic low-carbohydrate diets.

Johnston CS, Tjonn SL, Swan PD, White A, Hutchins H, Sears B · The American journal of clinical nutrition · 2006-05-11

Preclinical / mechanistic

282. Despite transient ketosis, the classic high-fat ketogenic diet induces marked changes in fatty acid metabolism in rats.

Taha AY, Ryan MA, Cunnane SC · Metabolism: clinical and experimental · 2004-10-18

Other

283. Long-term effects of a ketogenic diet in obese patients.

Dashti HM, Mathew TC, Hussein T, Asfar SK, Behbahani A, Khoursheed MA, Al-Sayer HM, Bo-Abbas YY, Al-Zaid NS · Experimental and clinical cardiology · 2009-07-31

Randomized clinical trial

284. Differential metabolic effects of saturated versus polyunsaturated fats in ketogenic diets.

Fuehrlein BS, Rutenberg MS, Silver JN, Warren MW, Theriaque DW, Duncan GE, Stacpoole PW, Brantly ML · The Journal of clinical endocrinology and metabolism · 2004-04-09

Case report / case series

285. Patient with gemfibrozil-controlled hypertriglyceridemia that developed acute pancreatitis after starting ketogenic diet.

Buse GJ, Riley KD, Dress CM, Neumaster TD · Current surgery · 2004-03-31

Other

286. Effects of the ketogenic diet in the glucose transporter 1 deficiency syndrome.

Klepper J, Diefenbach S, Kohlschütter A, Voit T · Prostaglandins, leukotrienes, and essential fatty acids · 2003-06-06

Review

287. A review of low-carbohydrate ketogenic diets.

Westman EC, Mavropoulos J, Yancy WS, Volek JS · Current atherosclerosis reports · 2003-10-04

Other

288. Metabolic syndrome and low-carbohydrate ketogenic diets in the medical school biochemistry curriculum.

Feinman RD, Makowske M · Metabolic syndrome and related disorders · 2008-03-29

Observational human study

289. Effect of a high-fat ketogenic diet on plasma levels of lipids, lipoproteins, and apolipoproteins in children.

Kwiterovich PO, Vining EP, Pyzik P, Skolasky R, Freeman JM · JAMA · 2003-08-21

Randomized clinical trial

290. A prospective study: growth and nutritional status of children treated with the ketogenic diet.

Liu YM, Williams S, Basualdo-Hammond C, Stephens D, Curtis R · Journal of the American Dietetic Association · 2003-06-05

Other

291. A ketogenic diet favorably affects serum biomarkers for cardiovascular disease in normal-weight men.

Sharman MJ, Kraemer WJ, Love DM, Avery NG, Gómez AL, Scheett TP, Volek JS · The Journal of nutrition · 2002-07-05

Case report / case series

292. Acute pancreatitis causing death in a child on the ketogenic diet.

Stewart WA, Gordon K, Camfield P · Journal of child neurology · 2001-09-29

Review

293. [The return to the ketogenic diet. What role does it play in the treatment of refractory seizures of infancy?].

Moreno Villares JM, Oliveros-Leal L, Simón-Heras R, Mateos-Beato F · Revista de neurologia · 2001-09-20

Preclinical / mechanistic

294. Lipid and fatty acid profiles in rats consuming different high-fat ketogenic diets.

Dell CA, Likhodii SS, Musa K, Ryan MA, Burnham WM, Cunnane SC · Lipids · 2001-06-01

Preclinical / mechanistic

295. Induction of the apolipoprotein AI gene by fasting: a relationship with ketosis but not with ketone bodies.

Haas MJ, Reinacher D, Pun K, Wong NC, Mooradian AD · Metabolism: clinical and experimental · 2001-01-06

Other

296. Growth and nutritional outcomes of children treated with the ketogenic diet.

Couch SC, Schwarzman F, Carroll J, Koenigsberger D, Nordli DR, Deckelbaum RJ, DeFelice AR · Journal of the American Dietetic Association · 1999-12-28

Review

297. Implementing a ketogenic diet based on medium-chain triglyceride oil in pediatric patients with cancer.

Nebeling LC, Lerner E · Journal of the American Dietetic Association · 1995-06-01

Preclinical / mechanistic

298. Pyruvate metabolism by lymphocytes: evidence for an additional ketogenic tissue.

Curi R, Williams JF, Newsholme EA · Biochemistry international · 1989-10-01

Case report / case series

299. Therapeutic effects of a ketogenic diet in Rett syndrome.

Haas RH, Rice MA, Trauner DA, Merritt TA · American journal of medical genetics. Supplement · 1986-01-01

Other

300. Early biochemical and EEG correlates of the ketogenic diet in children with atypical absence epilepsy.

Ross DL, Swaiman KF, Torres F, Hansen J · Pediatric neurology · 1985-03-01

Preclinical / mechanistic

301. [Effect of ketogenic diet on the convulsive threshold and brain amino acid and monoamine levels in young mice].

Otani K, Yamatodani A, Wada H, Mimaki T, Yabuuchi H · No to hattatsu = Brain and development · 1984-01-01

Preclinical / mechanistic

302. Effects of ketogenic diet on electroconvulsive threshold and brain contents of adenosine nucleotides.

Nakazawa M, Kodama S, Matsuo T · Brain & development · 1983-01-01

Other

303. Effect of ketogenic diets in gestation on some characteristics of carbohydrate metabolism in fetal pig brain and liver.

Rosebrough RW, Steele NC, Frobish LT · Growth · 1981-01-01

Other

304. Respiratory quotients lower than 0.70 in ketogenic diets.

Schutz Y, Ravussin E · The American journal of clinical nutrition · 1980-06-01

Review

305. The ketogenic diet: mechanism of anticonvulsant action.

Withrow CD · Advances in neurology · 1980-01-01

Preclinical / mechanistic

306. Protective effects of ketogenic diets on signs of hypoglycemia.

Johnson WA, Weiner MW · Diabetes · 1978-11-01

Other

307. Lipid metabolism in the neonate. III. The ketogenic effect of Intralipid infusion in the neonate.

Andrew G, Chan G, Schiff D · The Journal of pediatrics · 1978-06-01

Other

308. Medium chain triglyceride oil ketogenic diets in the treatment of childhood epilepsy.

Clark BJ, House FM · Journal of human nutrition · 1978-04-01

Other

309. Medium-chain triglycerides in a ketogenic diet.

Stephenson JB, House FM, Stromberg P · Developmental medicine and child neurology · 1977-10-01

Preclinical / mechanistic

310. Ketogenic response to medium-chain triglyceride load in the rat.

Bach A, Schirardin H, Weryha A, Bauer M · The Journal of nutrition · 1977-10-01

Preclinical / mechanistic

311. Experimental hyperosmolar diabetic syndrome. Ketogenic response to medium-chain triglycerides.

Gordon EE, Duga J · Diabetes · 1975-03-01

Preclinical / mechanistic

312. Glucogenic and ketogenic capacities of lard, safflower oil, and triumdecanoin in fasting rats.

Anderson RL, Boggs RW · The Journal of nutrition · 1975-02-01

Preclinical / mechanistic

313. An animal model for the ketogenic diet.

Appleton DB, DeVivo DC · Epilepsia · 1974-06-01

Other

314. Ketogenic diet containing medium-chain triglycerides.

Signore JM · Journal of the American Dietetic Association · 1973-03-01

Other

315. Short-term effect of Ketogenic diet and Low-calorie diet on Ketometabolism and lipid metabolism.

Bahrami F, Buetler E, Freiburghaus K, Seubnooch P, Bally L, Maurer J, Flück CE, Wiest R, Masoodi M · The Journal of nutritional biochemistry · 2025-11-18

Clinical trial / intervention

316. Medium-chain triglycerides and ketogenic diet prevent alterations of the gut microbiome in transgenic Alzheimer's disease mice.

M'Bra PEH, Suárez-Uribe I, Avino M, Ng Kwan Lim E, Mayhue M, Balthazar P, Aumont A, Prévost K, Massé E, Fernandes KJL · Communications biology · 2025-12-07

Preclinical / mechanistic

317. Ketogenic Nutrition in Combination With PPARα Activation Induced Metabolic Failure and Exacerbated Muscle Weakness in Septic Mice.

Lauwers C, Vankrunkelsven W, Derde S, Vander Perre S, Derese I, Pauwels L, Vanhorebeek I, Libbrecht L, Vermeersch P, Gunst J, Van den Berghe G, Casaer MP, Langouche L · Journal of cachexia, sarcopenia and muscle · 2025-10-17

Other

318. Gut microbiota regulates hepatic ketogenesis and lipid accumulation in ketogenic diet-induced hyperketonemia by disrupting bile acid metabolism.

Luo Z, Huang Y, Yong K, Wu D, Zheng L, Yao X, Shen L, Yu S, Wang B, Cao S · Gut microbes · 2025-04-23

Randomized clinical trial

319. Adaptive Ketogenic-Mediterranean Protocol (AKMP) in Real Clinical Practice: 14-Week Pre-Post Cohort Study on Glucolipid Markers and Safety.

García-Gorrita C, San Onofre N, Merino-Torres JF, Soriano JM · Nutrients · 2025-11-14

Clinical trial / intervention

320. Case series: Effects of a ketogenic diet on cardiometabolic health in seven outpatients with bipolar disorder.

Schreel L, Bürkle M, Thiem A, von Baehr V, Sauren J, Keferstein G · Frontiers in nutrition · 2025-10-07

Clinical trial / intervention

321. A long-term ketogenic diet causes hyperlipidemia, liver dysfunction, and glucose intolerance from impaired insulin secretion in mice.

Gallop MR, Vieira RFL, Mower PD, Matsuzaki ET, Liou W, Smart FE, Roberts S, Evason KJ, Holland WL, Chaix A · Science advances · 2025-09-19

Preclinical / mechanistic

322. Dietary lipids, not ketone body metabolites, influence intestinal tumorigenesis in a ketogenic diet.

Shay JES, Chi F, Tzouanas CN, Hoeve JT, Williams KJ, Sever T, Fuentes I, Yilmaz ÖH · bioRxiv : the preprint server for biology · 2025-09-13

Randomized clinical trial

323. The Effect of Short-Term Healthy Ketogenic Diet Ready-To-Eat Meals Versus Healthy Ketogenic Diet Counselling on Weight Loss in Overweight Adults: A Pilot Randomized Controlled Trial.

Tay MHJ, Yap QV, Lim SL, Ong YWY, Wee VCHT, Khoo CM · Nutrients · 2025-08-01

Preclinical / mechanistic

324. Ramipril and ketogenic diet response in cognitive dysfunction of insulin-resistant rats.

Abdel-Kareem NM, Elshazly SM, Abd El Fattah MA, Zaitone SA, Elmasry TA, Saleh A, Abd El-Haleim EA · Frontiers in pharmacology · 2025-07-11

Clinical trial / intervention

325. Rosuvastatin Improved LDL Subfractions Profile in a Patient with Type 1 Diabetes Following a Ketogenic Diet: A Case Report.

Janić M, Lunder M, Janež A, Šabović M, Maggio V, Rizzo M · Current vascular pharmacology · 2025-07-02

Other

326. Persistent hypercholesterolemia due to weight maintenance via a ketogenic diet in anorexia nervosa: A case report.

Nohara C, Ayani N, Suzuki C, Kobayashi H, Yamano S, Matsuoka T · PCN reports : psychiatry and clinical neurosciences · 2025-05-20

Systematic review / meta-analysis

327. Effects of ketogenic diets on polycystic ovary syndrome: a systematic review and meta-analysis.

Cannarella R, Rubulotta M, Leonardi A, Crafa A, Calvo A, Barbagallo F, La Vignera S, Calogero AE · Reproductive biology and endocrinology : RB&E · 2025-05-20

Case report / case series

328. Low-density lipoprotein cholesterol elevation, ketogenic diets, body mass index, and heterozygous ABCG5 genetic variation: Review, case report, and large population analysis.

Schaefer EJ, Tedder B, Asztalos BF, Callu R, Geller AS, Diffenderfer MR, Roth M · Journal of clinical lipidology · 2025-03-21

Preclinical / mechanistic

329. Mitochondrial ACSS1-K635 acetylation knock-in mice exhibit altered liver lipid metabolism on a ketogenic diet.

Xu G, Schell J, Quan S, Gao Y, Wei SJ, Pan M, Han X, Li G, Zhou D, Jiang H, Dong FF, Munkácsy E, Horikoshi N, Gius D · Free radical biology & medicine · 2025-03-10

Preclinical / mechanistic

330. Hepatic toll of keto: unveiling the inflammatory and structural consequences of ketogenic diet in rats.

Rezazadeh K, Barzegar M, Nezamdoost E, Shoaran M, Abbasi MM, Ghasemi B, Madadi S, Raeisi S · BMC nutrition · 2025-04-09

Preclinical / mechanistic

331. Vegetal oil-based ketogenic diet improves inflammation and fibrosis in experimental metabolic dysfunction-associated steatohepatitis.

Provera A, Ramavath NN, Gadipudi LL, Vecchio C, Caputo M, Antonioli A, Tini S, Sheferaw AN, Reano S, Filigheddu N, Manfredi M, Barberis E, Cocolin L, Ferrocino I, Locatelli M, Caprio M, Tacke F, Albano E, Prodam F, Sutti S · Frontiers in immunology · 2025-04-01

Other

332. [ON THE ANTI-KETOGENIC ACTIVITY OF GLYOXYLIC ACID].

CHEVPILO Ia, PRONINA ZV, KOKUNIN VA · Ukrains'kyi biokhimichnyi zhurnal · 1964-01-01

Other

333. [Effects of a ketogenic diet on the glyco-lipidic metabolism in obese subjects of pre-puberal age].

Del Guercio MJ, Carnelutti M, Cantone A · La Pediatria · 1967-03-01

Lipid Energy Model / LMHR Recent peer-reviewed literature

Source-verified selection covering the LMHR phenotype, LDL-C response to carbohydrate restriction, the Lipid Energy Model, coronary imaging evidence, and published scientific critiques.

Meta-analysis

1. Increased low-density lipoprotein cholesterol on a low-carbohydrate diet in adults with normal but not high body weight: A meta-analysis

Soto-Mota A, Flores-Jurado Y, Norwitz NG, Feldman D, Pereira MA, Danaei G, Ludwig DS · American Journal of Clinical Nutrition · 2024-03

Human clinical evidence

2. Carbohydrate Restriction-Induced Elevations in LDL-Cholesterol and Atherosclerosis: The KETO Trial

Budoff M, Manubolu VS, Kinninger A, Norwitz NG, Feldman D, Wood TR, et al. · JACC Advances · 2024-08-28

Human crossover study

3. Thyroid markers and body composition predict LDL-cholesterol change in lean healthy women on a ketogenic diet: experimental support for the lipid energy model

Cooper ID, Sanchez-Pizarro C, Norwitz NG, Feldman D, Kyriakidou Y, Edwards K, et al. · Frontiers in Endocrinology · 2023-12-21

Human observational evidence

4. Elevated LDL Cholesterol with a Carbohydrate-Restricted Diet: Evidence for a "Lean Mass Hyper-Responder" Phenotype

Norwitz NG, Feldman D, Soto-Mota A, Kalayjian T, Ludwig DS · Current Developments in Nutrition · 2021-11-30

Clinical review

5. Ketogenic Diets and Low-Density Lipoprotein Cholesterol in Adults With Normal Weight: An Emerging Clinical Challenge

DiMattia ZS, Petersen KS · Journal of the American Heart Association · 2026-05-05

Mechanistic model / review

6. The Lipid Energy Model: Reimagining Lipoprotein Function in the Context of Carbohydrate-Restricted Diets

Norwitz NG, Soto-Mota A, Kaplan B, Ludwig DS, Budoff M, Kontush A, Feldman D · Metabolites · 2022-05-20

Scientific commentary / critique

7. Evidence for a Lean Mass Hyperresponder Phenotype Is Lacking with Increases in LDL Cholesterol of Clinical Significance in All Categories of Response to a Carbohydrate-Restricted Diet

Moore JM, Diefenbach D, Nadendla M, Hiebert N · Current Developments in Nutrition · 2022-05-27

Thyroid Disorders Recent peer-reviewed literature

Evidence is ordered preferentially by systematic reviews/meta-analyses and recent high-level evidence, followed by recent clinical studies and then relevant mechanistic work.

Recent review · 2025

1. Ketogenic Diet and Thyroid Function

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Human metabolic study

2. Thyroid markers and body composition predict LDL-cholesterol change in lean healthy women on a ketogenic diet: experimental support for the lipid energy model

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Clinical / mechanistic study

3. Could the Ketogenic Diet induce a shift in thyroid function?

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Preclinical / mechanistic

4. Effect of long-term use of very low-carbohydrate Ketogenic diet on the thyroid gland and adipose tissue of adult male albino rats (biochemical and histological study).

Ibrahim RA, Elwaddah NM, Aziz NM, Yousef JE, Abd El-Aleem SAE, Saber EA · Journal of molecular histology · 2026-07-30

Randomized clinical trial

5. The ketogenic diet alleviates autoimmune thyroiditis caused by Th17/Treg imbalance by inhibiting the HMGB1/NLRP3 signaling pathway.

Luo Y, Gao H, Wang M, Wang Z, Jin Z, Song N, Liu Z, Yang X · PloS one · 2026-05-08

Preclinical / mechanistic

6. Effects of Ketogenic Diet on Behavioral, Metabolic, and Peripheral Tissue Changes in a Propylthiouracil-Induced Hypothyroidism Model.

Akkaya EC, Ilgin R, Kızıldağ S, Argon A, Hoşgörler F · Medical principles and practice : international journal of the Kuwait University, Health Science Centre · 2026-05-08

Other

7. Low-Carbohydrate (Ketogenic) Diet in Children with Obesity: Part 2-Hormonal Effects of the Ketogenic Diet.

Paskaleva IN, Kaleva NN, Dimcheva TD, Ivanov IS · Children (Basel, Switzerland) · 2026-03-14

Other

8. Metabolomics reveals the implication of acetoacetate and ketogenic diet therapy in radioiodine-refractory differentiated thyroid carcinoma.

Wang J, Xu Q, Xuan Z, Mao Y, Tang X, Yang K, Song F, Zhu X · The oncologist · 2024-01-05

Review

9. Obesity and Obesity-Related Thyroid Dysfunction: Any Potential Role for the Very Low-Calorie Ketogenic Diet (VLCKD)?

Chapela SP, Simancas-Racines A, Ceriani F, Martinuzzi ALN, Russo MP, Zambrano AK, Simancas-Racines D, Verde L, Muscogiuri G, Katsanos CS, Frias-Toral E, Barrea L · Current nutrition reports · 2024-03-25

Randomized clinical trial

10. Correction: Could the ketogenic diet induce a shift in thyroid function and support a metabolic advantage in healthy participants? A pilot randomized-controlled-crossover trial.

Iacovides S, Maloney SK, Bhana S, Angamia Z, Meiring RM · PloS one · 2023-11-27

Case report / case series

11. Persistent hypercalcemia mimicking hypophosphatasia after discontinuation of a ketogenic diet: a case report.

Sasidharan Pillai S, Robilliard R, Fredette ME, Serrano-Gonzalez M, Scully KJ · Journal of pediatric endocrinology & metabolism : JPEM · 2023-10-05

Systematic review / meta-analysis

12. Effects of the ketogenic diet on bone health: A systematic review.

Garofalo V, Barbagallo F, Cannarella R, Calogero AE, La Vignera S, Condorelli RA · Frontiers in endocrinology · 2023-02-02

Randomized clinical trial

13. Could the ketogenic diet induce a shift in thyroid function and support a metabolic advantage in healthy participants? A pilot randomized-controlled-crossover trial.

Iacovides S, Maloney SK, Bhana S, Angamia Z, Meiring RM · PloS one · 2022-06-03

Other

14. The effect of ketogenic diet on thyroid functions in children with drug-resistant epilepsy.

Yılmaz Ü, Nalbantoğlu Ö, Güzin Y, Edizer S, Akışin Z, Pekuz S, Kırkgöz HH, Yavuz M, Ünalp A, Özkan B · Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2021-04-12

Case report / case series

15. Hypercalcemia in Children Using the Ketogenic Diet: A Multicenter Study.

Hawkes CP, Roy SM, Dekelbab B, Frazier B, Grover M, Haidet J, Listman J, Madsen S, Roan M, Rodd C, Sopher A, Tebben P, Levine MA · The Journal of clinical endocrinology and metabolism · 2020-08-23

Other

16. Effects of modified Atkins diet on thyroid function in adult patients with pharmacoresistant epilepsy.

Molteberg E, Thorsby PM, Kverneland M, Iversen PO, Selmer KK, Nakken KO, Taubøll E · Epilepsy & behavior : E&B · 2020-07-19

Other

17. Longitudinal Change in Thyroid Hormone Levels in Children with Epilepsy on a Ketogenic Diet: Prevalence and Risk Factors.

Lee YJ, Nam SO, Kim KM, Kim YM, Yeon GM · Journal of epilepsy research · 2017-12-31

Other

18. Changes of thyroid hormonal status in patients receiving ketogenic diet due to intractable epilepsy.

Kose E, Guzel O, Demir K, Arslan N · Journal of pediatric endocrinology & metabolism : JPEM · 2016-07-14

Other

19. Hormonal and metabolic changes induced by an isocaloric isoproteinic ketogenic diet in healthy subjects.

Fery F, Bourdoux P, Christophe J, Balasse EO · Diabete & metabolisme · 1982-12-01

Preclinical / mechanistic

20. Effect of thyroid state on ketogenic capacity of the isolated perfused liver of starved rats.

Müller MJ, Köster H, Seitz HJ · Biochimica et biophysica acta · 1981-12-23

Review

21. Ketogenic Diet and Thyroid Function: A Delicate Metabolic Balancing Act.

Vranjić P, Vuković M, Blažetić S, Viljetić B · Current issues in molecular biology · 2025-08-28

Cushing Syndrome Recent peer-reviewed literature

Source-audited selection from the connected PDF archive. Systematic reviews/meta-analyses and recent human evidence are prioritized when available; sparse areas are explicitly kept sparse.

Disease-focused review

1. Very Low-Calorie Ketogenic Diet: A Potential Application in the Treatment of Hypercortisolism Comorbidities

Original publication title: Very Low-Calorie Ketogenic Diet: A Potential Application in the Treatment of Hypercortisolism Comorbidities

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Clinical/review evidence

2. Nutritional Intervention in Cushing’s Disease: The Potential Role of a Ketogenic Strategy

Original publication title: Nutritional Intervention in Cushing’s Disease: The Potential Role of a Ketogenic Strategy

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Clinical trial / intervention

3. Nutritional Intervention in Cushing's Disease: The Ketogenic Diet's Effects on Metabolic Comorbidities and Adrenal Steroids.

Guarnotta V, Amodei R, Di Gaudio F, Giordano C · Nutrients · 2023-11-02

Case report / case series

4. Ketogenic Diet Initially Masks Symptoms of Hypercortisolism in Cushing's Disease.

Dugandzic MK, Pierre-Michel EC, Kalayjian T · Metabolites · 2022-10-28

Clinical trial / intervention

5. The Role of Very Low Calorie Ketogenic Diet in Sympathetic Activation through Cortisol Secretion in Male Obese Population.

Polito R, Messina G, Valenzano A, Scarinci A, Villano I, Monda M, Cibelli G, Porro C, Pisanelli D, Monda V, Messina A · Journal of clinical medicine · 2021-09-18

Polyendocrine Metabolic Ovarian Syndrome (PMOS, formerly PCOS) Recent peer-reviewed literature

Source-audited references from the connected PDF archive. Only papers directly relevant to this topic and ketogenic therapy/ketosis are shown.

1. The effects of ketogenic diet on polycystic ovary syndrome: a systematic review

Bibliographic record reviewed for inclusion in the curated Scientific Library.

2. Effects of the very low-carbohydrate ketogenic diet in women with polycystic ovary syndrome: a systematic review with meta-analysis of clinical trials

Bibliographic record reviewed for inclusion in the curated Scientific Library.

3. Polycystic Ovary Syndrome and the Effects of a Ketogenic Diet: A Scoping Review

Bibliographic record reviewed for inclusion in the curated Scientific Library.

4. A Ketogenic Diet Followed by Gradual Carbohydrate Reintroduction Restores Menstrual Cycles in Women with Polycystic Ovary Syndrome with Oligomenorrhea Independent of Body Weight Loss

Bibliographic record reviewed for inclusion in the curated Scientific Library.

5. Ketogenic diet improves fertility in patients with polycystic ovary syndrome

Bibliographic record reviewed for inclusion in the curated Scientific Library.

6. Effects of ketogenic diet on weight loss parameters among obese or overweight patients with polycystic ovary syndrome: a systematic review and meta-analysis of randomized controlled trials

Bibliographic record reviewed for inclusion in the curated Scientific Library.

7. Effects of Ketogenic Diet on Reproductive Hormones in PCOS

Bibliographic record reviewed for inclusion in the curated Scientific Library.

8. Low-Calorie Ketogenic Diet: Potential Application in PCOS

Bibliographic record reviewed for inclusion in the curated Scientific Library.

9. Ketogenic Diet as a Possible Non-pharmacological Therapy in Main Endocrine Diseases of the Female Reproductive System

Bibliographic record reviewed for inclusion in the curated Scientific Library.

10. Ketogenic Diet as Medical Prescription in Women with Polycystic Ovary Syndrome

Bibliographic record reviewed for inclusion in the curated Scientific Library.

11. Effects of a ketogenic diet in overweight women with PCOS

Bibliographic record reviewed for inclusion in the curated Scientific Library.

12. Effects of a Ketogenic Diet in Overweight and Obese Women with PCOS

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Systematic review & meta-analysis · 2024

13. Effects of Ketogenic Diet on Weight Loss Parameters among Patients with Overweight or Obesity and Polycystic Ovary Syndrome: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

Original publication title: Effects of Ketogenic Diet on Weight Loss Parameters among Patients with Overweight or Obesity and Polycystic Ovary Syndrome: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Clinical review / human evidence

14. The Impact of Nutritional Therapy in the Management of Overweight/Obese PCOS Patients Candidates for IVF

Original publication title: The Impact of Nutritional Therapy in the Management of Overweight/Obese PCOS Patients Candidates for IVF

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Review · 2023

15. Low-Calorie Ketogenic Diet: Potential Application in Polycystic Ovary Syndrome

Original publication title: Low-Calorie Ketogenic Diet: Potential Application in Polycystic Ovary Syndrome

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Comprehensive review

16. Pathophysiology and Nutritional Approaches in Polycystic Ovary Syndrome: A Comprehensive Review

Original publication title: Pathophysiology and Nutritional Approaches in Polycystic Ovary Syndrome: A Comprehensive Review

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Human clinical study

17. Effects of a Ketogenic Diet in Overweight Women with Polycystic Ovary Syndrome

Original publication title: Effects of a Ketogenic Diet in Overweight Women with Polycystic Ovary Syndrome

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Human clinical study

18. Effects of a Mixed Ketogenic Diet in Overweight and Obese Women with PCOS

Original publication title: Effects of a Mixed Ketogenic Diet in Overweight and Obese Women with PCOS

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Human reproductive study

19. Does the Ketogenic Diet Improve the Quality of Ovarian Function in Women with Obesity?

Original publication title: Does the Ketogenic Diet Improve the Quality of Ovarian Function in Women with Obesity?

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Randomized clinical trial

20. Ketogenic diet combined with probiotics for polyendocrine metabolic ovarian syndrome: research progress from the perspective of the gut microbiota-host metabolic axis.

Yang Y, Dai F, He X, Zhao P, Chen Q · Frontiers in nutrition · 2026-09-02

Systematic review / meta-analysis

21. Inconsistency Between the Definition of "Real-World Exposure" and the Predefined Inclusion Criteria in a Systematic Review on the Ketogenic Diet for Polycystic Ovary Syndrome.

Zhu H, Lu C, Shen L · Clinical nutrition (Edinburgh, Scotland) · 2026-07-20

Systematic review / meta-analysis

22. Ketogenic diet as a therapeutic intervention for biochemical hyperandrogenism in PCOS women with obesity or overweight: a meta-analytic study.

Maseroli E, Alfaroli C, Cirillo M, Ravelli SA, Lambrinoudaki I, Focardi M, Virgili G, Vignozzi L · Journal of endocrinological investigation · 2026-06-13

Systematic review / meta-analysis

23. Effects of the Ketogenic Diet on Gonadal Hormones: A Systematic Review.

Lima M, Fabe J, Grigolon RB, Ceolin G, Palma N, Gerchman F, Brietzke E, Gomes FA · Nutrition reviews · 2026-05-12

Other

24. Low-Carbohydrate (Ketogenic) Diet in Children with Obesity: Part 2-Hormonal Effects of the Ketogenic Diet.

Paskaleva IN, Kaleva NN, Dimcheva TD, Ivanov IS · Children (Basel, Switzerland) · 2026-03-14

Randomized clinical trial

25. The effects of portfolio moderate-carbohydrate and ketogenic diets on anthropometric indices, metabolic status, and hormonal levels in overweight or obese women with polycystic ovary syndrome: a randomized controlled trial.

Sharifi M, Saber A, Moludi J, Salimi Y, Jahan-Mihan A · Nutrition journal · 2024-12-02

Systematic review / meta-analysis

26. The effects of ketogenic diet on metabolic and hormonal parameters in patients with polycystic ovary syndrome: a systematic review and meta-analysis of clinical trials.

Eshaghhosseiny N, Ahmadi M, Izadi B, Vali M, Akbari M, Azari I, Akbari H · Journal of diabetes and metabolic disorders · 2024-05-21

Preclinical / mechanistic

27. A ketogenic diet alleviates the apoptosis of granulosa cells by inhibiting the activation of cGAS-STING signaling pathway in PCOS mice.

Zhao B, Wu H, Yao Q, Bai W, Kang J · Cell communication and signaling : CCS · 2024-11-27

Observational human study

28. Ketogenic diet improves fertility in patients with polycystic ovary syndrome: a brief report.

Tsushima Y, Nachawi N, Pantalone KM, Griebeler ML, Alwahab UA · Frontiers in nutrition · 2024-09-12

Preclinical / mechanistic

29. Effect of the ketogenic diet on gut microbiome composition and metabolomics in polycystic ovarian syndrome rats induced by letrozole and a high-fat diet.

Wang R, Zhao Y, Fang X, Miao C, Ren N, Chen Y, Cheng W, Zhang Q · Nutrition (Burbank, Los Angeles County, Calif.) · 2023-06-08

Clinical trial / intervention

30. Effects of Ketogenic Diet on Reproductive Hormones in Women With Polycystic Ovary Syndrome.

Khalid K, Apparow S, Mushaddik IL, Anuar A, Rizvi SAA, Habib A · Journal of the Endocrine Society · 2023-09-07

Clinical trial / intervention

31. Low-Calorie Ketogenic Diet: Potential Application in the Treatment of Polycystic Ovary Syndrome in Adolescents.

Calcaterra V, Cena H, Sottotetti F, Hruby C, Madini N, Zelaschi N, Zuccotti G · Nutrients · 2023-08-15

Randomized clinical trial

32. A comparison of the portfolio low-carbohydrate diet and the ketogenic diet in overweight and obese women with polycystic ovary syndrome: study protocol for a randomized controlled trial.

Najafabadi MS, Moludi J, Salimi Y, Saber A · Trials · 2023-08-09

Clinical trial / intervention

33. Adding a ketogenic dietary intervention to IVF treatment in patients with polycystic ovary syndrome improves implantation and pregnancy.

Palafox-Gómez C, Ortiz G, Madrazo I, López-Bayghen E · Reproductive toxicology (Elmsford, N.Y.) · 2023-06-07

Preclinical / mechanistic

34. Corrigendum to "Ketogenic diet restores hormonal, apoptotic/proliferative balance and enhances the effect of metformin on a letrozole-induced polycystic ovary model in rats" [Life Sci. 313 (2022) 121285].

Ahmed AF, Sharkawi SS, AbdelHameed SS, Bayoumi AM, Moussa RS, Alhakamy NA, Al Sadoun H, Mansouri RA, El-Moselhy MA, El-Daly M, Anter AF · Life sciences · 2023-06-02

Randomized clinical trial

35. Efficacy of very low-calorie ketogenic diet with the Pronokal® method in obese women with polycystic ovary syndrome: a 16-week randomized controlled trial.

Pandurevic S, Mancini I, Mitselman D, Magagnoli M, Teglia R, Fazzeri R, Dionese P, Cecchetti C, Caprio M, Moretti C, Sicinska J, Agostini A, Gazineo D, Godino L, Sajoux I, Fanelli F, Meriggiola CM, Pagotto U, Gambineri A · Endocrine connections · 2023-06-12

Clinical trial / intervention

36. Effects of a ketogenic diet on reproductive and metabolic phenotypes in mice with polycystic ovary syndrome†.

Liu S, Yao Q, Li X, Wu H, Sun C, Bai W, Kang J · Biology of reproduction · 2022-05-13

Other

37. Short-time effects of ketogenic diet or modestly hypocaloric Mediterranean diet on overweight and obese women with polycystic ovary syndrome.

Cincione IR, Graziadio C, Marino F, Vetrani C, Losavio F, Savastano S, Colao A, Laudisio D · Journal of endocrinological investigation · 2022-11-19

Other

38. Correction: Ketogenic Diet as Medical Prescription in Women with Polycystic Ovary Syndrome (PCOS).

Barrea L, Verde L, Camajani E, Cernea S, Frias-Toral E, Lamabadusuriya D, Ceriani F, Savastano S, Colao A, Muscogiuri G · Current nutrition reports · 2023-02-16

Guideline / consensus

39. Ketogenic Diet as Medical Prescription in Women with Polycystic Ovary Syndrome (PCOS).

Barrea L, Verde L, Camajani E, Cernea S, Frias-Toral E, Lamabadusuriya D, Ceriani F, Savastano S, Colao A, Muscogiuri G · Current nutrition reports · 2023-01-25

Preclinical / mechanistic

40. Ketogenic diet restores hormonal, apoptotic/proliferative balance and enhances the effect of metformin on a letrozole-induced polycystic ovary model in rats.

Ahmed AF, Sharkawi SS, AbdelHameed SS, Bayoumi AM, Moussa RS, Alhakamy NA, Al Sadoun H, Mansouri RA, El-Moselhy MA, El-Daly M, Anter AF · Life sciences · 2022-12-13

Clinical trial / intervention

41. Effects of a ketogenic diet in women with PCOS with different uric acid concentrations: a prospective cohort study.

Yang M, Bai W, Jiang B, Wang Z, Wang X, Sun Y, Liu F, Cui G, Song X, Li J, Wu F · Reproductive biomedicine online · 2022-04-02

Other

42. Effects of Mixed of a Ketogenic Diet in Overweight and Obese Women with Polycystic Ovary Syndrome.

Cincione RI, Losavio F, Ciolli F, Valenzano A, Cibelli G, Messina G, Polito R · International journal of environmental research and public health · 2021-11-27

Randomized clinical trial

43. Ketogenic diet in women with polycystic ovary syndrome and liver dysfunction who are obese: A randomized, open-label, parallel-group, controlled pilot trial.

Li J, Bai WP, Jiang B, Bai LR, Gu B, Yan SX, Li FY, Huang B · The journal of obstetrics and gynaecology research · 2021-01-18

Review

44. [Ketogenic Diet and its Evidence-Based Therapeutic Implementation in Endocrine Diseases].

Stocker RK, Reber Aubry E, Bally L, Nuoffer JM, Stanga Z · Praxis · 2019-06-13

Clinical trial / intervention

45. Current Insights Into Inositol Isoforms, Mediterranean and Ketogenic Diets for Polycystic Ovary Syndrome: From Bench to Bedside.

Muscogiuri G, Palomba S, Laganà AS, Orio F · Current pharmaceutical design · 2016-06-01

Other

46. The effects of a low-carbohydrate, ketogenic diet on the polycystic ovary syndrome: a pilot study.

Mavropoulos JC, Yancy WS, Hepburn J, Westman EC · Nutrition & metabolism · 2005-12-16

Systematic review / meta-analysis

47. The effects of ketogenic diet on polycystic ovary syndrome: A systematic review and meta-analysis.

Arsenaki E, Stathi D, Triantafyllidis KK, Seldon Y, Bobotis S, Lockett G, Haran S, Kyrgiou M, Saso S, Kechagias KS · Clinical nutrition (Edinburgh, Scotland) · 2025-12-03

Clinical trial / intervention

48. Therapeutic effectiveness of low-calorie ketogenic diet on body composition and biochemical parameters in polycystic ovary syndrome - An ıntervention study.

Seven Avuk H, Baş M · Nutricion hospitalaria · 2025-11-13

Clinical trial / intervention

49. Breaking the metabolic-inflammatory vicious cycle in polycystic ovary syndrome: a comparative review of ketogenic and high-fat diets.

Yang W, Pang N, He X · Lipids in health and disease · 2025-10-06

Systematic review / meta-analysis

50. Effects of ketogenic diets on polycystic ovary syndrome: a systematic review and meta-analysis.

Cannarella R, Rubulotta M, Leonardi A, Crafa A, Calvo A, Barbagallo F, La Vignera S, Calogero AE · Reproductive biology and endocrinology : RB&E · 2025-05-20

Systematic review / meta-analysis

51. Impact of Ketogenic Diet on Weight, Metabolic, and Endocrine Parameters in Women with Polycystic Ovary Syndrome: A Systematic Review and Meta-Analysis.

Turetta C, Turetta C, Giannini A, Tarsitano MG, Gianfrilli D, Paoli A, Kontopantelis E, De Angelis E, Minnetti M, Poggiogalle E, Colizza A, De Vincentiis M, Laganà AS, Bogani G, Palaia I, Muzii L, Di Donato V · Gynecologic and obstetric investigation · 2025-02-20

Neurology & Neuroscience

Epilepsy Recent peer-reviewed literature

Source-audited references from the connected PDF archive. Only papers directly relevant to this topic and ketogenic therapy/ketosis are shown.

1. The Effect of Ketonemia on the Course of Epilepsy

Wilder RM. Mayo Clinic Bulletin. 1921;2:307-308. Historical ketogenic-diet reference.

2. High Fat Diets in Epilepsy

Wilder RM. Mayo Clinic Bulletin. 1921;2:308. Historical ketogenic-diet reference.

3. The Ketogenic Diet in the Treatment of Epilepsy: A Preliminary Report

Peterman MG. American Journal of Diseases of Children. 1924;28:28-33. Historical ketogenic-diet reference.

4. The Ketogenic Diet in Epilepsy

Peterman MG. JAMA. 1925;84:1979-1983. Historical ketogenic-diet reference.

5. The Ketogenic Diet in the Treatment of Idiopathic Epilepsy

Talbot FB, Metcalf K, Moriarty ME. American Journal of Diseases of Children. 1926;32:316-318. Historical ketogenic-diet reference.

6. Long-term effectiveness and tolerability of ketogenic diet therapy in patients with genetic epilepsy

Bibliographic record reviewed for inclusion in the curated Scientific Library.

7. Effects of ketogenic diet on the classification and functional composition of intestinal flora in children with mitochondrial epilepsy

Bibliographic record reviewed for inclusion in the curated Scientific Library.

8. Ketogenic diet for epilepsy control

Bibliographic record reviewed for inclusion in the curated Scientific Library.

9. Ketogenic Diets in the Management of Lennox-Gastaut Syndrome

Bibliographic record reviewed for inclusion in the curated Scientific Library.

10. The Metabolic Role of Ketogenic Diets in Treating Epilepsy

Bibliographic record reviewed for inclusion in the curated Scientific Library.

11. Ketogenic and Low FODMAP Diet in Therapeutic Management of a Young Autistic Patient with Epilepsy and Dysmetabolism

Bibliographic record reviewed for inclusion in the curated Scientific Library.

12. Improving the effects of ketogenic diet therapy in children with drug-resistant epilepsy

Bibliographic record reviewed for inclusion in the curated Scientific Library.

13. Optimal clinical management of children receiving dietary therapies for epilepsy

Bibliographic record reviewed for inclusion in the curated Scientific Library.

14. The effectiveness of the ketogenic diet in drug-resistant epilepsy

Bibliographic record reviewed for inclusion in the curated Scientific Library.

15. Use of ketogenic diet therapy in infants with epilepsy

Bibliographic record reviewed for inclusion in the curated Scientific Library.

16. The ketogenic diet increases Neuregulin 1 in an epilepsy model

Bibliographic record reviewed for inclusion in the curated Scientific Library.

17. Treatment of refractory epilepsy: comparison of ketogenic dietary approaches

Bibliographic record reviewed for inclusion in the curated Scientific Library.

18. Seizure modulation by the gut microbiota and ketogenic diet

Bibliographic record reviewed for inclusion in the curated Scientific Library.

19. The gut microbiome and the ketogenic diet in epilepsy

Bibliographic record reviewed for inclusion in the curated Scientific Library.

20. The efficacy of non-fasting ketogenic diet protocols in epilepsy

Bibliographic record reviewed for inclusion in the curated Scientific Library.

21. Super-Refractory Status Epilepticus: Prognosis and Recent Advances in Management including ketogenic therapy

Bibliographic record reviewed for inclusion in the curated Scientific Library.

22. Stress biomarkers in adult patients with drug-resistant epilepsy during ketogenic diet therapy

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Review

23. The Interplay Between Microbiota and the Brain-Gut Axis in Epilepsy Treatment

Original publication title: The Interplay Between Microbiota and the Brain-Gut Axis in Epilepsy Treatment

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Mechanistic / translational

24. Fecal Transfers from Children on the Ketogenic Diet Mimic Key Metabolic Effects

Original publication title: Fecal Transfers from Children on the Ketogenic Diet Mimic Key Metabolic Effects

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Review

25. Epilepsy, Gut Microbiota, and Circadian Rhythm

Original publication title: Epilepsy, Gut Microbiota, and Circadian Rhythm

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Mechanistic review

26. Ketone Bodies and Brain Metabolism: New Insights and Perspectives for Neurological Diseases

Original publication title: Ketone Bodies and Brain Metabolism: New Insights and Perspectives for Neurological Diseases

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Clinical evidence

27. Intractable Seizures in Children With Type 1 Diabetes Treated With Ketogenic Dietary Therapy

Original publication title: Intractable Seizures in Children With Type 1 Diabetes Treated With Ketogenic Dietary Therapy

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Human neurophysiology study

28. Graph Theory-Based Electroencephalographic Connectivity During Ketogenic Diet Therapy

Original publication title: Graph Theory-Based Electroencephalographic Connectivity During Ketogenic Diet Therapy

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Prospective clinical study

29. Prospective Controlled Study of Efficacy and Influencing Factors of Ketogenic Diet Therapy in Epilepsy

Original publication title: Prospective Controlled Study of Efficacy and Influencing Factors of Ketogenic Diet Therapy in Epilepsy

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Clinical evidence

30. Ketogenic Diet in Infants With Early-Onset Epileptic Encephalopathy

Original publication title: Ketogenic Diet in Infants With Early-Onset Epileptic Encephalopathy

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Clinical evidence

31. Ketogenic Diet Therapy for Refractory Epilepsy

Original publication title: Ketogenic Diet Therapy for Refractory Epilepsy

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Review / clinical evidence

32. Ketogenic Diet in the Treatment of Epilepsy

Original publication title: Ketogenic Diet in the Treatment of Epilepsy

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Human clinical study

33. Effects of Classic Ketogenic Diet in Children With Refractory Epilepsy

Original publication title: Effects of Classic Ketogenic Diet in Children With Refractory Epilepsy

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Review

34. Diet in the Treatment of Epilepsy: What We Know

Original publication title: Diet in the Treatment of Epilepsy: What We Know

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Clinical analysis

35. Analysis of Factors That May Affect the Effectiveness of Ketogenic Diet Therapy in Epilepsy

Original publication title: Analysis of Factors That May Affect the Effectiveness of Ketogenic Diet Therapy in Epilepsy

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Clinical evidence

36. Effectiveness and safety analysis of ketogenic diet therapy for drug-resistant epilepsy caused by structural pathology

Original publication title: Effectiveness and safety analysis of ketogenic diet therapy for drug-resistant epilepsy caused by structural pathology

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Observational human study

37. [Effectiveness and tolerability of ketogenic diet therapy in children with genetic developmental and epileptic encephalopathy onset within 2 years of age].

Song TY, Deng J, Chen CH, Wang XH, Tian XJ, Wu ML, Wang X, Zhang HW, Chen XY, Wang Y, Niyazi Y, Abudureyimu G, Fang F · Zhonghua er ke za zhi = Chinese journal of pediatrics · 2026-09-15

Other

38. Comment on: ketogenic diet for status epilepticus in adult intensive care unit patients: a standard operating procedure.

Schmidbauer ML, Dimitriadis K · Neurological research and practice · 2026-09-09

Randomized clinical trial

39. A randomized controlled trial of a multimodality digital health intervention to aid the delivery of the modified ketogenic diet therapy for epilepsy: The Keto eCoach trial protocol.

Kaul N, Vivash L, Chen S, King L, Johns H, Churilov L, Chen Z, Nicolo JP, Heaven D, Meredith E, Ervine R, Todd L, Zappa B, Ademi Z, Geethadevi GM, Erlichster M, Skafidas E, O'Brien TJ, Kwan P · Epilepsia open · 2026-09-07

Other

40. Influence of baseline nutritional status on ketogenic diet efficacy in children with drug-resistant epilepsy.

Chen YT, Lee LJ, Fan PC, Lee WT · Pediatric research · 2026-08-27

Other

41. Do Children with Drug-Resistant Epilepsy Exhibit the Same Eating Habits and Feeding Difficulties as Their Healthy Peers? A Multifaceted Assessment of Eating Habits, Feeding Behaviors, and Nutritional Status in Pediatric Patients with Drug-Resistant Epilepsy on a Ketogenic Diet Compared with Healthy Children in Lower Silesia.

Gołąbek KD, Gruna-Ożarowska A, Wronowicz J, Regulska-Ilow B · Nutrients · 2026-08-26

Case report / case series

42. Management of ketogenic diet therapy in patients with ileostomy: A report of 2 cases.

Baker BJ, Olbina AE, Godfrey MA, Graber AE, Parrish TN, Delima SIR · Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition · 2026-08-25

Clinical trial / intervention

43. Epigenetic ageing is accelerated in drug-resistant epilepsy and dynamically modulated during ketogenic diet therapy.

Gervin K, Kverneland M, Nakken KO, Rudi K, Iversen PO, Selmer KK · EBioMedicine · 2026-08-22

Systematic review / meta-analysis

44. Impact of medium-chain triglyceride with and without ketogenic diet in the management of drug-resistant epilepsy: a systematic review.

Pellizzari M, De Clauser L, Mir-Majidi S, Leone A, Veggiotti P, Previtali R, Olivotto S, Bertoli S, De Amicis R · Nutritional neuroscience · 2026-08-20

Observational human study

45. Glucose Transporter Type 1 Deficiency Syndrome: Clinical Variability and Challenges in Ketogenic Diet Management in a Paediatric Case Series.

Viegas M, Baptista N, Martins F, Almeida J, Pereira C, Rodrigues F, Salgado J, Ribeiro J, Ferreira S, Diogo R · Journal of clinical medicine · 2026-08-19

Preclinical / mechanistic

46. Ketogenic diet attenuates seizures by promoting lipid droplet formation via peroxisome proliferator-activated receptor gamma signaling pathway.

Xi Z, Zhang W, Liu Q, Wang Q, Qi Y · Life sciences · 2026-08-19

Observational human study

47. Real-world experience with GLP-1 receptor agonists in adults with epilepsy following a modified atkins diet.

El Zibaoui R, McDonald TJW, Henry-Barron BJ, Vizthum D, Cervenka MC · Epilepsy research · 2026-08-14

Clinical trial / intervention

48. The ketogenic diet ameliorates behavioral abnormalities in a PTZ-induced zebrafish larvae model via modulating neurotransmitter balance.

Yang X, Lin J, Zhang Q, Xia Y, Zhou S, Wang Y, Li Q, Yu L · IBRO neuroscience reports · 2026-08-04

Systematic review / meta-analysis

49. Corrigendum to "The efficacy and safety of ketogenic diet therapy among adolescents and adults with drug resistant epilepsy: A systematic review and meta-analysis" [Seizure: European Journal of Epilepsy volume 140 (2026) p39-51].

Farrar T, D'Silva A, Cardamone M, Palacios-Derflingher L, Farrar MA · Seizure · 2026-08-03

Randomized clinical trial

50. The Ketogenic Diet in the Prevention and Treatment of Hypertension (HTN).

Rodzeń Ł, Dyńka D, Rodzeń M, Karakuła-Juchnowicz H, Łojko D, Kraszewski S, Grzywacz Ż, Bikman B, Unwin J, Unwin D, Fazio S · Biomedicines · 2026-07-31

Observational human study

51. Continuing Ketogenic Diet Therapy in Setting of Hypercalcemia.

Sarabia L, Wetzel A, Sawyer J, Giannini S, Imel E, Delima SI · Journal of child neurology · 2026-07-30

Observational human study

52. Ketogenic diet for pediatric drug-resistant epilepsy: sleep, children's psychosocial functioning, and maternal mental health.

Nassar MF, El-Rashidy OF, Shata MO, ElHagaar MA, Abdelmageed RI · Pediatric research · 2026-07-28

Observational human study

53. Effects of ketogenic diet therapy in outpatient anti epileptic drug cost reduction and parental satisfaction among children with intractable epilepsy.

Rafli A, Handryastuti S, Soebadi A, Santoso DN, Rahmawati I, Pramana R, Ramadhan R, Anthony CP, Mangunatmadja I · Frontiers in neurology · 2026-07-17

Other

54. Metabolomic Profiling of Plasma in Children with Drug-Resistant Epilepsy: The Effect of the Ketogenic Diet on Energy and Amino Acid Pathways.

Cieślak M, Gątarek P, Safiński P, Przyslo L, Kałużna-Czaplińska J · Nutrients · 2026-07-17

Systematic review / meta-analysis

55. Ketogenic diet in adult obesity: safety, limitations, and evidence from various clinical applications.

Kacprzak U, Adamaszek N, Buczkowska A, Sochowska J, Flejszman M, Danieluk J, Wójcik J, Stochaj L, Gliński M, Dołęga-Mostowska D · Roczniki Panstwowego Zakladu Higieny · 2026-07-14

Clinical trial / intervention

56. Incidence and risk factors of ketogenic diet-associated nephrolithiasis in children with drug-resistant epilepsy: A tertiary care center experience.

Amer F, Alotaibi W, Bashir S, AlBaradie R, Al Hany E, Ali M, Alamri A, Mir A · Epilepsy research · 2026-07-13

Review

57. Reviewer Comment on Sharma et al. "Effect of Concurrent Anti-Seizure Medications on the Efficacy of the Ketogenic Diet in Children with Epilepsy".

Datta AN · The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques · 2026-07-13

Clinical trial / intervention

58. Predicting the efficacy of classic ketogenic diet therapy in children with refractory epilepsy using dynamic changes in the glucose-ketone index (GKI).

Li J, Wang T, Yu L, Ni Y, Li Y, Zhang Y, Zhou S, Wang Y · Seizure · 2026-07-12

Clinical trial / intervention

59. Ketogenic Diet-Mediated Immunomodulation for Prevention of Epilepsia Partialis Continua in Rasmussen's Encephalitis: Review and Case Study.

Salgado Rueda SA, Moreno Guerra N, Vargas Rojas JL · Case reports in neurology · 2026-07-10

Observational human study

60. Ketogenic diet enhances cardiac autonomic stability in pediatric drug-resistant epilepsy: A longitudinal heart rate variability study.

Karaca NB, Kavgacı A, Terlemez S, Aktaş E, Serdaroğlu E, Hirfanoğlu T, Serdaroğlu A, Demir E, Arhan E · Epilepsy research · 2026-07-10

Clinical trial / intervention

61. The Ketogenic Diet: A Possible Intervention for Improving Hippocampal Function in Neurological Disorders.

Jahanmehr D, Ahmadi A, Fadaei M, Sangi Nasab Lahijan A, Shafiee Sabet M, Kalantari Dehaghi H, Asadi-Golshan R · Nutrition reviews · 2026-07-10

Observational human study

62. Modified Atkins diet therapy in adult drug-resistant epilepsy: Quality of life and mental health outcomes.

Carneiro RAVD, Cardoso RM, Lunardi MDS, Lima MC, Anzani S, Darella AX, Salvador MT, de Paula Moraes T, Sostizzo NC, Venske DK, Moreira JD, Ribeiro LC, Borgatto AF, Lin K · Epilepsia · 2026-07-09

Observational human study

63. Neurodevelopmental Risk Factors and Comparative Efficacy of Ketogenic Diet in Children With Spike-Wave Activation in Sleep: A Cohort Study.

Ma J, Wang J, Song X, Xie L, Li X, Hu Y, Hong S, Jiang L, Li T · Pediatric neurology · 2026-07-08

Systematic review / meta-analysis

64. Ketogenic diet therapies for the treatment of drug-resistant epilepsy in children and adults: A systematic review.

Vaccarezza MM, Sanguine VL, Balaciano G · PloS one · 2026-07-02

Other

65. Critical Nutrients in the Ketogenic Diet for Adolescents Based on Optimized Hypothetical Meal Plans.

Assmann M, Albrecht I, Fischer T · Nutrients · 2026-06-27

Clinical trial / intervention

66. Quality of Life and Associated Factors in Primary Caregivers of Children with Refractory Epilepsy on Long-Term Ketogenic Diet: A Cross-Sectional Study.

Li X, Wang J, Yi X, Deng Q, Zhao Y, Liu Y · Healthcare (Basel, Switzerland) · 2026-06-18

Randomized clinical trial

67. Ketogenic Diet for Intensive Care Patients: A Scoping Review.

Bryła J, Szczupak M, Krupa-Nurcek S · Nutrients · 2026-06-16

Preclinical / mechanistic

68. Effect of the ketogenic diet on absence seizures in rats with genetic absence epilepsy.

Acikgoz NB, Toplu-Hocaoglu A, Yildirim BA, Yananli HR, Turkdogan D, Onat F · Epilepsy research · 2026-06-16

Case report / case series

69. Corpus Callosotomy in LIS1 Lissencephaly: Postoperative Ketogenic Diet-Related Metabolic Derangements and Feeding Intolerance.

Jalal A, Waggoner R, Lau J, George AJ, Salman H, Salman B · Cureus · 2026-06-13

Clinical trial / intervention

70. Use of medium-chain triglycerides in paediatric patients with drug-resistant epilepsy without ketogenic therapy.

Viollaz R, Alberti MJ, de Clauser L, Vilavedra JF · Epilepsy & behavior : E&B · 2026-06-12

Observational human study

71. Early Electroencephalographic Changes After Ketogenic Diet Initiation Are Associated With Clinical Response in Pediatric Drug-Resistant Epilepsy.

Yavuz M, Unalp A, Gulagız F, Guzin Y, Yılmaz U · Seizure · 2026-06-10

Review

72. The Ketogenic Diet: Three Decades Later.

Kossoff EH, Turner Z, Hartman AL · Journal of child neurology · 2026-06-04

Clinical trial / intervention

73. Ketogenic diet in children with epilepsy: A bibliometric and science mapping analysis of global research.

Kilic KM, Aydin H · Brain & development · 2026-06-03

Other

74. Cook4Keto: Bridging culinary expertise and clinical practice to improve adherence to ketogenic diet therapy in drug-refractory epilepsy.

Castellucci G, Calka A, Pedapati R, Manchala DA, Ivaniuk A, Jesus-Ribeiro J, Sheikh I, Beniczky S · Epileptic disorders : international epilepsy journal with videotape · 2026-06-01

Case report / case series

75. Ketogenic diet therapy for epilepsy in conjunction with concurrent inflammatory bowel disease: Case series and recommendations.

Kossoff EH, Bessone SK, Chatfield B, Jerger L, Madsen S, Parrish T, Turner Z, Vanatta L, Worden LT · Epilepsy research · 2026-05-31

Other

76. A price check on the ketogenic diet for adults with epilepsy in Australia.

King L, Maccarrone J, Kaur A, Chen S, Kwan P, O'Brien TJ, Kaul N · Epilepsia open · 2026-05-25

Clinical trial / intervention

77. The Ketogenic Diet Fails to Mitigate Seizures and Neuroinflammatory Responses in a Mouse Model of Virus-Induced Epilepsy.

Meili CH, Allen K, Doty DJ, Del Fiol S, DePaula-Silva AB · bioRxiv : the preprint server for biology · 2026-05-21

Observational human study

78. Effect of Concurrent Anti-Seizure Medications on the Efficacy of the Ketogenic Diet in Children with Epilepsy.

Sharma S, Aschner A, Kabir N, Donner E · The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques · 2026-05-21

Case report / case series

79. Reversible high-fat ketogenic formula-induced hypertriglyceridemia in a child with NALCN mutation on a ketogenic diet: a case report.

Elbarky A, Dawoud H, Elballat KE, Gamal H, Salamah A · Molecular biology reports · 2026-05-20

Preclinical / mechanistic

80. Fourier Transform Infrared Imaging Supported by Raman Spectroscopy Reveals Biochemical Changes in Adult Rat Brains Following Prenatal Exposure to a Ketogenic Diet.

Rugiel M, Setkowicz Z, Drozdz A, Wilk A, Brylowska Z, Chwiej J · ACS chemical neuroscience · 2026-05-19

Systematic review / meta-analysis

81. The efficacy and safety of ketogenic diet therapy among adolescents and adults with drug resistant epilepsy: A systematic review and meta-analysis.

Farrar T, D'Silva A, Cardamone M, Palacios-Derflingher L, Farrar MA · Seizure · 2026-05-17

Observational human study

82. Risks of using standard reference ranges for carbohydrate and lipid metabolism in low-carbohydrate diets: insights from ketogenic diet therapy in children with refractory epilepsy.

Matsui K, Mori M, Kumada T · Diabetology international · 2026-05-15

Other

83. Critical Nutrients in Ketogenic Diets for Infants and Children Under Ten Years of Age-A Hypothetical Study.

Assmann M, Albrecht I, Fischer T · Nutrients · 2026-05-14

Guideline / consensus

84. Ketogenic diet therapy for children with super-refractory status epilepticus in intensive care: International clinical practice recommendations.

Blackford R, Whiteley VJ, Hardy I, Armeno M, Bollard T, Cross JH, Eltze C, George S, Howard C, Nijstad AL, Talzzia E, Paget C, Ray S, Simpson Z, Song-Pozderac E, Szmurlo A, Tan-Smith C, Vanatta L, van der Louw E, Schoeler NE, Ketogenic Dietitians Research Network · Epilepsia open · 2026-05-14

Observational human study

85. Micronutrient intake in adults with drug-resistant epilepsy treated with the modified Atkins diet needs monitoring.

Kjendbakke I, Selmer KK, Nakken KO, Hofoss D, Iversen PO, Kverneland M · Frontiers in nutrition · 2026-05-07

Observational human study

86. Gut microbiota shifts and short-chain fatty acids alterations in pediatric epilepsy patients on a Mediterranean ketogenic diet.

Zouganeli S, Mitsou EK, Yannakoulia M, Intze E, Mountzouris KC, Fessatou S, Attilakos A, Kyriacou A, Dinopoulos A · Epileptic disorders : international epilepsy journal with videotape · 2026-05-07

Observational human study

87. Concurrent use of ketogenic diet therapy and cannabidiol in children and adults with epilepsy: A multicenter retrospective cohort study.

Hinkley LM, Cervenka MC, Bessone SK, Turner Z, Kossoff EH · Epilepsy research · 2026-05-05

Guideline / consensus

88. Ketoproof? A systematic classification of pharmaceutical excipients for ketogenic diet therapy.

El Abdouni S, den Uil MG, Kafa Z, Ribeiro TS, van der Louw EJTM, Ruijgrok EJ, Nijstad AL · International journal of clinical pharmacy · 2026-05-05

Systematic review / meta-analysis

89. Exploring the rise of the ketogenic dietary therapies for epilepsy in Latin America: A systematic review and meta-analysis.

Shibaki R, de Oliveira Franco MDNS, Camargo JSL, Citro GM, Ramos EM, Bruzzone M · Epilepsy research · 2026-04-30

Other

90. Ketogenic diet therapy for epilepsy in Australia: insights from the Pharmaceutical Benefits Scheme.

Kaul N, King L, Chen S, Kwan P, O'Brien TJ · Internal medicine journal · 2026-04-29

Preclinical / mechanistic

91. From gut to brain: short-term ketogenic diet alleviates status epilepticus-induced cognitive deficits in rats.

Chen Y, Xu W, Hou Q, Jiang Y · Frontiers in physiology · 2026-04-28

Observational human study

92. Efficacy of Treating Post-Traumatic Epilepsy in Children With Ketogenic Diet.

Choi HW, Bhalla S, Holt P, Johnson M · Journal of child neurology · 2026-04-25

Observational human study

93. Long term outcomes of children started on the Ketogenic diet for pediatric super refractory status epilepticus- 15 years single center experience.

Hommady R, Lowe H, Dickson J, Owusu K, Kobayashi J, Hahn C, Zak M, Hopkins S, Jain P, McKinnon N, Donner E, Sharma S · Seizure · 2026-04-16

Other

94. Can Artificial Intelligence Chatbots Plan Therapeutic Ketogenic Diets for Children With Epilepsy?

Ajmera F, Lowe H, Dickson J, Owusu K, Zak M, Sharma S · Journal of human nutrition and dietetics : the official journal of the British Dietetic Association · 2026-04-13

Clinical trial / intervention

95. Emergence of hypomania and mania following initiation of a ketogenic diet: case series.

Palmer CM · Frontiers in nutrition · 2026-04-08

Observational human study

96. Clinical and laboratory outcomes of ketogenic versus glycine-restricted diet in nonketotic hyperglycinemia: A comparative study.

Bozacı AE, Erdal İ, Öner G, Clark ÖA, Köken ÖY, Soyuçen E · Molecular genetics and metabolism · 2026-04-07

Other

97. Investigation of the implementation and utilization of ketogenic diet therapy in China : For the Commission on Standardized Development of Epilepsy Centers and Commission on Ketogenic Diet, China Association Against Epilepsy.

Xi W, Lin Y, Tian S, Liao J, Wang Y · Acta epileptologica · 2026-04-01

Clinical trial / intervention

98. Modulatory role of the ketogenic diet in glial scar formation after traumatic brain injury: A Fourier transform infrared, Raman, and X-ray fluorescence microscopy study.

Kawon K, Setkowicz Z, Czyzycki M, Rauk Z, Wilk A, Slawek A, Cieslak J, Aquilanti G, Carlomagno I, Drozdz A, Chwiej J · Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy · 2026-03-31

Clinical trial / intervention

99. Ketogenic Diet and Brain Health: Cerebrovascular Mechanisms, Neuroprotection, and Translational Implications.

Mózes N, Fehér Á, Csípő T, Fazekas-Pongor V, Lipécz Á, Major D, Lehoczki A, Dósa N, Pártos K, Csík B, Yi HW, Kaposvári C, Horváth K, Fekete M · Nutrients · 2026-03-29

Preclinical / mechanistic

100. Sexual dimorphism shapes renal metabolic adaptation to a ketogenic diet.

Kelly ME, Hoffner LA, Ramirez CB, Anica AL, Kim J, Tong G, Kim Y, Mannepalli V, Choi W, Jang KH, Alam YH, Jung S, Le J, Lopez ML, Rubtsova VI, Bae H, Chun Y, Song WS, Tamburini IJ, Schuster VL, Anton-Culver H, Lau WL, Martinez TF, Lee G, Jang C · Cell reports · 2026-03-28

Clinical trial / intervention

101. The Ketogenic Diet and Potential Micronutrient Risks in Drug-Resistant Epilepsy Management: A Literature Review.

Singh B, Botten P, Richardson KP, Weaver C, Purohit S · Nutrients · 2026-03-27

Observational human study

102. Challenges in epilepsy management in the Eastern Mediterranean (Part I): Disparities in pharmacological treatment and ketogenic diet access.

Shaaban S, Al-Ramadhani R, Alkalbani L, Kurdi D, Almasaad B, Tilako A, Dhia RB, Nderbe Melom C, Al Shehhi W, AlKhaja M, Albastaki HAK, Abdulrahman A, Ibrahim A, Benkirane N, Mohsen S · Epileptic disorders : international epilepsy journal with videotape · 2026-03-27

Guideline / consensus

103. ILAE dietary treatments task force special report: Maternal ketogenic diet exposure in epilepsy pregnancy registries-A call to action.

Kverneland M, De Giorgis V, Healy L, Faltersack K, McDonald TJW, Armeno M, Cervenka MC, Devlin A · Epilepsia open · 2026-03-25

Other

104. "Not always the magic bullet"-Insufficient seizure control by ketogenic dietary therapies in Glut1 Deficiency Syndrome.

Klepper J, Runkel E, Kiesel L · Epilepsia open · 2026-03-14

Clinical trial / intervention

105. DNA methylation of antiseizure medication metabolism genes and pharmacokinetic changes in adult epilepsy patients treated with the modified Atkins diet.

Gervin K, Kverneland M, Nakken KO, Rudi K, Iversen PO, Landmark CJ, Selmer KK · Genes & nutrition · 2026-03-13

Randomized clinical trial

106. From clinical practice to mechanistic insights in ketogenic diets for epilepsy.

Figueroa AG, Joshi CN, Patel MN · The Lancet. Neurology · 2026-03-11

Preclinical / mechanistic

107. Ketogenic diet causes bone loss in growing and adult mice and reduces the skeletal response to exercise.

Osipov B, Robison L, Hanel J, Orr SV, Lin YY, Buxton A, Rahmati M, Tseng MC, Renato MR, Shenoy R, Bhat AS, Saiz A, Ferguson VL, Loots GG, Christiansen BA · Bone · 2026-03-09

Other

108. Electroencephalography-Based Machine Learning Models for Predicting Ketogenic Diet Outcomes in Pediatric Drug-Resistant Epilepsy.

Hung PL, Chen JP, Lin TP, Hsieh TY, Chen YF, Su TY, Peng SJ · Pediatric neurology · 2026-02-19

Case report / case series

109. Ketogenic Diet as an Epigenetic Therapy in SETD1B-Related Epilepsy.

Tsang E, Gloss BS, Hayes JP, Holland AJA, Menezes MP, Branson JA, Mohammad SS, Yan JJ, Patel S, Han VX, Dale RC · Annals of clinical and translational neurology · 2026-02-19

Other

110. Knowledge and attitudes toward ketogenic dietary therapy in adults with epilepsy.

Lutz MT, Alex M, Brandhoff F, Mayer T · Epilepsy & behavior : E&B · 2026-02-17

Other

111. Case Report: Management of Hemiconvulsion Hemiplegic Epilepsy Syndrome Utilizing Ketamine and Ketogenic Diet.

Thomas J, Metzler L, Viorritto E, Salazar NC · Pediatric neurology · 2026-02-05

Observational human study

112. Efficacy differences between tocilizumab and ketogenic diet during acute phase of febrile Infection-Related epilepsy syndrome in children: A retrospective cohort study.

Yan X, He J, Cheng M, Hong S, Jiang L, Han W · Epilepsy & behavior : E&B · 2026-02-02

Clinical trial / intervention

113. From Refractory Epilepsy to Neurodegeneration: Emerging Mechanistic and Clinical Insights Into the Ketogenic Diet.

Ahire C, Yadav R, Bhamare UU, Kaur G, Palkar MB · FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026-01-25

Clinical trial / intervention

114. Ketogenic diet improves cognitive impairment in rats with temporal lobe epilepsy by activating the Nrf2/HO-1/GPX4 signaling axis to inhibit ferroptosis.

Yang L, Wang J, Wang X, Li B, Zhao D, Li C, Li C, Cui Y, Chen Q, Yang Y, Gu J, Hou S, Zhang L, Qiang Y · Free radical biology & medicine · 2026-01-21

Review

115. Rewiring the brain: Ketogenic diet and gut microbiota in nervous system development.

Jędrusik J, Setkowicz Z · Nutrition (Burbank, Los Angeles County, Calif.) · 2026-01-10

Observational human study

116. Managing GLUT 1 Deficiency with the Ketogenic Diet: A Retrospective Look at Seizures, Medications, and Side Effects in a Pediatric Cohort.

Morris S, Blackford R, Lowman W, Fisher B · Journal of child neurology · 2026-01-09

Observational human study

117. Ketogenic Diet in Super-Refractory Status Epilepticus: A Retrospective Cohort Study with Severity-Matched Controls in Critically Ill Adults.

Feil K, Kindzierski S, Single C, Geiger-Primo L, Schweikert D, Adolph M, Kegele J, Lerche H, Ziemann U, Möller L, Mengel A, IGNITE Study Group · Neurocritical care · 2026-01-08

Observational human study

118. Weaning from ketogenic diet therapy in children with epilepsy: Insights from a retrospective study.

Donnard N, Dozières-Puyravel B, Geraldes K, Perrot C, Quéméner V, Goujon E, Truchy P, Nasser H, Mauvais FX, Danse M, Auvin S · Epilepsia · 2025-12-24

Clinical trial / intervention

119. Ketogenic Diet Reduces Alcohol Consumption and Improves Memory and Sociability in Mice.

Bechard AR, Storie K, Grzeskowiak A, Forcier M, Nunez Y, Brambhatt D, Azurin S, Connell R, Kamel J · Journal of studies on alcohol and drugs · 2025-12-15

Observational human study

120. Benefits and adverse effects of ketogenic diet treatment in pediatric patients with inborn errors of metabolism.

Wesół-Kucharska D, Kaczor MA, Emczyńska-Seliga EEV · Advances in clinical and experimental medicine : official organ Wroclaw Medical University · 2025-11-22

Observational human study

121. One Center's Experience With Outpatient Initiation of Ketogenic Therapy in Infants 18 Months or Younger.

Becu CT, Vanatta L, Sports CE, Jarrar R · Journal of child neurology · 2025-11-11

Systematic review / meta-analysis

122. Modified Atkins Diet versus low glycemic index treatment in children with drug-resistant epilepsy: A systematic review and meta-analysis.

Sharawat IK, Panda P, Dawman L, Gupta D, Panda PK · Seizure · 2024-12-04

Observational human study

123. The effect of the modified Atkins diet and anti-seizure medications on lipid marker levels in adults with epilepsy.

Muller AL, Diaz-Arias L, Cervenka MC, McDonald TJW · Nutritional neuroscience · 2024-09-04

Review

124. Ketogenic diet therapy for the treatment of pediatric epilepsy.

Haridas B, Testino A, Kossoff EH · Epileptic disorders : international epilepsy journal with videotape · 2024-12-12

Other

125. Survey of Latin American ketogenic diet centers: Challenges and success for "La Terapia Cetogénica".

Armeno M, Kossoff EH, Guilhoto L, Caraballo R · Epileptic disorders : international epilepsy journal with videotape · 2024-12-05

Other

126. Favorable response to ketogenic diet therapy in a patient with DYNC1H1-related epilepsy.

Phitsanuwong C, Schimpf S, Yano ST · Epilepsy & behavior reports · 2024-12-26

Review

127. Exploring ketogenic diet resistance in glucose transporter type 1 deficiency syndrome: A comprehensive review and critical appraisal.

Falsaperla R, Sortino V, Kluger GJ, Herberhold T, Rüegger A, Striano P, Ruggieri M, Klepper J, Ramantani G · Epilepsia open · 2024-12-06

Observational human study

128. Ketogenic diet treatment for super-refractory status epilepticus in the intensive care unit: feasibility, safety and effectiveness.

Ren Y, Zhang M, Fu X, Zhang Y, Liu F, Wu C, Shi H, Tian F, Liu G, Lin Y, Su Y, Chen W · Frontiers in neurology · 2025-01-13

Review

129. Ketogenic diet as a therapeutic approach in autism spectrum disorder: a narrative review.

Öztürk E, Aslan Çin NN, Cansu A, Akyol A · Metabolic brain disease · 2024-12-18

Observational human study

130. MicroRNAs as potential biomarkers of response to modified Atkins diet in treatment of adults with drug-resistant epilepsy: A proof-of-concept study.

Samões R, Cavalheiro A, Santos C, Lopes J, Teixeira C, Tavares MM, Carvalho C, Lemos C, E Costa PP, Cavaco S, Chaves J, Leal B · Epilepsy research · 2024-11-08

Observational human study

131. A case series of the efficacy and tolerability of ketogenic diet in children with drug-resistant epilepsy due to neonatal hypoglycemia.

Dou X, Wu Y, Liang L, Yang Y, Li F, Li X, Wang D · Epilepsy & behavior : E&B · 2024-10-30

Clinical trial / intervention

132. Ketogenic diet therapy for epilepsy: Clinical pearls.

Pinto AL, Montenegro MA, Valente K, Sampaio LB · Epilepsy & behavior : E&B · 2024-10-28

Preclinical / mechanistic

133. The hydroxycarboxylic acid receptor HCA2 is required for the protective effect of ketogenic diet in epilepsy.

Richardson JC, Higgins GA, Upton N, Massey P, Cunningham M, Wilson S, Holenz J, Taylor C, Lavrov A, Lin H, Matsuoka Y, Brown AJ · Pharmacology research & perspectives · 2024-09-19

Preclinical / mechanistic

134. Exogenous ketones exert antiseizure effects and modulate the gut microbiome and mycobiome in a clinically relevant murine model of epilepsy.

Mu C, Kesler M, Chen X, Shearer J, Teskey GC, Rho JM · Epilepsia · 2024-10-16

Observational human study

135. Ketogenic diet effectiveness is superior for drug resistant epilepsy with causative genetic mutation than those without genetic etiology.

Hsieh TY, Su TY, Hung KY, Hsu MS, Lin YJ, Kuo HC, Hung PL · Epilepsy & behavior : E&B · 2024-09-22

Other

136. Nice to know 2: The impact of NICE guidelines on ketogenic diet services in the UK and Ireland - An update.

Whiteley VJ, Schoeler NE, Ketogenic Dietitians Research Network · Journal of human nutrition and dietetics : the official journal of the British Dietetic Association · 2024-08-19

Observational human study

137. Ketogenic diet therapies as a non-pharmacological adjuvant in resistant epilepsy: retrospective analysis of adult outpatients in Colombia.

Ballesteros Tapias JK, Conde Hurtado DI, Castaño LH, Pérez AM · Nutritional neuroscience · 2024-04-15

Clinical trial / intervention

138. Ketogenic Diet and Neuroinflammation: Implications for Neuroimmunometabolism and Therapeutic Approaches to Refractory Epilepsy.

Guerreiro D, Almeida A, Ramalho R · Nutrients · 2024-11-22

Randomized clinical trial

139. Impact of L-carnitine supplementation on gastric emptying and bowel function in pediatric ketogenic diet therapy: a clinical trial.

Nassar MF, Shata MO, Awadallah SM, Youssef MA, Ibrahim HE · Scientific reports · 2024-11-15

Review

140. Ketogenic diets therapy in the management of epileptic spasms syndrome.

Wang M, Zhao F, Sun L, Yu Y, Zhang H · Frontiers in pediatrics · 2024-11-06

Preclinical / mechanistic

141. Element Changes Occurring in Brain Point at the White Matter Abnormalities in Rats Exposed to the Ketogenic Diet During Prenatal Life.

Rugieł M, Setkowicz Z, Czyzycki M, Simon R, Baumbach T, Chwiej J · ACS chemical neuroscience · 2024-10-23

Clinical trial / intervention

142. A Ketogenic Diet Affects Gut Microbiota by Regulating Gut Microbiota and Promoting Hippocampal TRHR Expression to Combat Seizures.

Xiong W, Lin X, Lin X, Wu L, Lin W · Journal of molecular neuroscience : MN · 2024-11-03

Observational human study

143. Ketogenic diet registry for epilepsy: A cross-sectional feasibility study.

Neal EG, Whiteley VJ, van der Louw E, Devlin AM, Eltze C, Pujar S, Simpson Z, Hardy I, Palmer A, Szmurlo A, Parker AP, Mills N, Ord R, Lagae L, Kerckhove KV, van den Berg S, Cross JH, Schoeler NE · European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society · 2024-10-28

Preclinical / mechanistic

144. Association between seizure reduction during ketogenic diet treatment of epilepsy and changes in circulatory metabolites and gut microbiota composition.

Dahlin M, Wheelock CE, Prast-Nielsen S · EBioMedicine · 2024-11-04

Other

145. What do ketogenic dietitians and physicians need? A survey from the KetoCollegeAdvance™ training in United Kingdom.

Kossoff EH, Simpson Z, Fountain J · Epilepsy & behavior : E&B · 2024-10-11

Review

146. The role of ketogenic diets in the treatment of status epilepticus.

Schoeler NE · Epilepsy & behavior : E&B · 2024-10-09

Review

147. Categorizing Monogenic Epilepsies by Genetic Mechanisms May Predict Efficacy of the Ketogenic Diet.

Kim JA, Schimpf S, Yano ST, Nordli D, Phitsanuwong C · Pediatric neurology · 2024-07-30

Observational human study

148. [Micronutrients intake in patients with refractory epilepsy with ketogenic diet treatment].

Velandia S, Astudillo P, Acevedo K, Le Roy C · Andes pediatrica : revista Chilena de pediatria · 2023-09-28

Review

149. Acute Changes in Liver Function Tests During Initiation of Ketogenic Diet.

Katyayan A, Nayak A, Diaz-Medina G, Handoko M, Riviello JJ · Journal of child neurology · 2024-09-16

Review

150. A side-by-side comparison of fine-tuning options for treatment of medically refractory epilepsy: Antiseizure medications, vagus nerve stimulation and ketogenic diet therapies.

Bonno D, Vanatta L, Kossoff E · Epilepsy research · 2024-08-17

Clinical trial / intervention

151. Optimizing ketogenic diet therapy for childhood epilepsy: Identifying key factors for seizure control and psychomotor enhancement.

Tong X, Wang Q, Yang J, Zhou J, Chen X, Gan J, Cai Q, Yu T, Luo R · Epilepsia · 2024-08-27

Systematic review / meta-analysis

152. Nurture growth: Ketogenic diet therapy and growth velocity in infants under 12 months with epilepsy - A systematic review and infant data study.

Maass A, Sutter F, Trimmel-Schwahofer P, Lämmer C, Schoene-Bake JC, Schönlaub A, Höller A, Dressler A · Epilepsy & behavior : E&B · 2024-08-24

Observational human study

153. Factors associated with seizure response in adults with epilepsy on a modified Atkins diet.

Huerta N, Lu M, Henry-Barron BJ, Cervenka MC, McDonald TJW · Seizure · 2024-08-22

Observational human study

154. Maintenance of response to ketogenic diet therapy for drug-resistant epilepsy post diet discontinuation: A multi-centre case note review.

Schoeler NE, Ridout D, Neal EG, Becirovic M, Whiteley VJ, Meskell R, Lightfoot K, Mills N, Ives T, Bara V, Cameron E, Thomas P, Wilford E, Fox R, Fabe J, Leong JY, Tan-Smith C, Ketogenic Dietitians Research Network · Seizure · 2024-08-05

Preclinical / mechanistic

155. Ketogenic Diets Alter the Gut Microbiome, Resulting in Decreased Susceptibility to and Cognitive Impairment in Rats with Pilocarpine-Induced Status Epilepticus.

Li B, Ma Y, Wang X, Zhao D, Wang Z, Wang G, Li C, Yang L, Ji H, Liu K, Chen Q, Yang Y, Ma W, Du J, Ma L, Zhang L, Qiang Y · Neurochemical research · 2024-06-27

Clinical trial / intervention

156. Sequential Treatment with Modified Atkins Diet and Low Glycemic Index Treatment for Drug-Resistant Epilepsy in Children.

Mulyan A, Kaushik JS, Dabla S · Neuropediatrics · 2024-06-21

Guideline / consensus

157. Human milk and breastfeeding during ketogenic diet therapy in infants with epilepsy: Clinical practice guideline.

van der Louw E, Trimmel-Schwahofer P, Devlin A, Armeno M, Thompson L, Cross JH, Auvin S, Dressler A · Developmental medicine and child neurology · 2024-04-26

Clinical trial / intervention

158. Short-term effectiveness and side effects of ketogenic diet for drug-resistant epilepsy in children with genetic epilepsy syndromes.

Muthaffar OY, Alyazidi AS, Alsowat D, Alasiri AA, Albaradie R, Jad LA, Kayyali H, Jan MMS, Bamaga AK, Alsubaie MA, Daghistani R, Baeesa SS, Alaifan MA, Makraz A, Alsharief AN, Naseer MI · Frontiers in neurology · 2024-09-18

Other

159. Clinician Understanding, Acceptance and utilization of Ketogenic diet therapy for epilepsy in Australia and New Zealand: An online survey.

Farrar TE, D'Silva A, Cardamone M, Bartley ML, Wong CH, Farrar MA · Epilepsy & behavior reports · 2024-09-16

Review

160. Putative Role of Adenosine A1 Receptors in Exogenous Ketone Supplements-Evoked Anti-Epileptic Effect.

Kovács Z, Rauch E, D'Agostino DP, Ari C · International journal of molecular sciences · 2024-09-12

Other

161. Fueling Recovery: The Therapeutic Role of Ketogenic Diet in Neurological Pathologies.

Khan AYY, Khalid Rana MA, Mehmood Qadri H, Amir A · Cureus · 2024-09-05

Clinical trial / intervention

162. A New Nomenclature for the Very Low-Calorie Ketogenic Diet (VLCKD): Very Low-Energy Ketogenic Therapy (VLEKT). Ketodiets and Nutraceuticals Expert Panels: "KetoNut", Italian Society of Nutraceuticals (SINut) and the Italian Association of Dietetics and Clinical Nutrition (ADI).

Barrea L, Caprio M, Grassi D, Cicero AFG, Bagnato C, Paolini B, Muscogiuri G · Current nutrition reports · 2024-07-23

Preclinical / mechanistic

163. Effective reduction in seizure severity and prevention of a fatty liver by a novel low ratio ketogenic diet composition in the rapid kindling rat model of epileptogenesis.

Meeusen H, Kalf RS, Broekaart DWM, Silva JP, Verkuyl JM, van Helvoort A, Gorter JA, van Vliet EA, Aronica E · Experimental neurology · 2024-06-12

Systematic review / meta-analysis

164. Efficacy of anti-seizure medications and alternative therapies (ketogenic diet, CBD, and quinidine) in KCNT1-related epilepsy: A systematic review.

Gras M, Bearden D, West J, Nabbout R · Epilepsia open · 2024-06-22

Randomized clinical trial

165. Efficacy and tolerability of classical and polyunsaturated fatty acids ketogenic diet in controlling paediatric refractory epilepsy - A randomized study.

Ray S, Nathan J, Godhia M · Epilepsy research · 2024-06-13

Randomized clinical trial

166. The use of ketogenic diets in children living with drug-resistant epilepsy, glucose transporter 1 deficiency syndrome and pyruvate dehydrogenase deficiency: A scoping review.

Cameron T, Allan K, Kay Cooper · Journal of human nutrition and dietetics : the official journal of the British Dietetic Association · 2024-06-04

Preclinical / mechanistic

167. Dietary fiber content in clinical ketogenic diets modifies the gut microbiome and seizure resistance in mice.

Özcan E, Yu KB, Dinh L, Lum GR, Lau K, Hsu J, Arino M, Paramo J, Lopez-Romero A, Hsiao EY · bioRxiv : the preprint server for biology · 2024-07-31

Case report / case series

168. The Efficacy of a Ketogenic Diet in a Case With Febrile Infection-Related Epilepsy Syndrome in the Chronic Phase: A Case Report.

Yoneno S, Baba S, Sumitomo N, Miyamoto K, Takahashi K, Shimizu-Motohashi Y, Saito T, Komaki H · Cureus · 2024-07-09

Other

169. Ketogenic diet therapy leads to antiseizure medication reduction in children and adults with drug-resistant epilepsy.

He F, Ye L, Wang L, Zhou J, Shao X, Miao P, Wang S, Li H, Ding Y, Wang S · CNS neuroscience & therapeutics · 2024-06-29

Systematic review / meta-analysis

170. Literature Review: Support for caregivers of children on the ketogenic diet for epilepsy and other neurologic disorders.

Metzger S, Lee J, McDavid L · Epilepsy & behavior : E&B · 2024-05-16

Observational human study

171. Prospective study of the modified Atkins diet in adult drug-resistant epilepsy: effectiveness, tolerability, and adherence.

Alanis Guevara MI, García de Alba García JE, López Alanis AL, González Ojeda A, Fuentes Orozco C · Neurologia · 2023-04-28

Systematic review / meta-analysis

172. Modified Atkins Diet in Adolescents and Adults with Drug Resistant Epilepsy: A Systematic Review and Meta-Analysis.

Manral M, Tripathi S, Rawat D, Tripathi M · Journal of epilepsy research · 2024-06-30

Case report / case series

173. PURA-Related Neurodevelopmental Disorders with Epilepsy Treated with Ketogenic Diet: A Case-Based Review.

Falsaperla R, Sortino V, Schinocca MA, Fusto G, Rizzo R, Barberi C, Ruggieri M, Pappalardo XG · Genes · 2024-06-27

Systematic review / meta-analysis

174. Advances in Ketogenic Diet Therapies in Pediatric Epilepsy: A Systematic Review.

Parveen D, Jain V, Kannan D, Mandava P, Urazbayeva M, Marie C, Sanjeev JA, Patel P, McCarthy K, Wilson M, Patel U, Hsieh YC, Chavda D, Thakker Z · The primary care companion for CNS disorders · 2024-06-25

Clinical trial / intervention

175. Inflammation and oxidative stress in epileptic children: from molecular mechanisms to clinical application of ketogenic diet.

Ildarabadi A, Mir Mohammad Ali SN, Rahmani F, Mosavari N, Pourbakhtyaran E, Rezaei N · Reviews in the neurosciences · 2024-02-14

Guideline / consensus

176. Changes in pediatric referrals after the 2009 ketogenic diet consensus recommendations.

Stainman RS, Turner Z, Kossoff EH · Epilepsy & behavior : E&B · 2024-04-20

Observational human study

177. Diagnosis and treatment of growth hormone deficiency in children on the ketogenic diet: A case series.

Groveman S, Klepper J, Liesenkötter KP, Grimberg A, Bergqvist AGC · Epilepsia open · 2024-04-20

Systematic review / meta-analysis

178. Adherence to ketogenic dietary therapies in epilepsy: A systematic review of literature.

Lopes Neri LC, Guglielmetti M, Fiorini S, Pasca L, Zanaboni MP, de Giorgis V, Tagliabue A, Ferraris C · Nutrition research (New York, N.Y.) · 2024-03-21

Systematic review / meta-analysis

179. The impact of ketogenic diet on drug-resistant epilepsy in children: A comprehensive review and meta-analysis.

Mustafa MS, Shafique MA, Aheed B, Ashraf F, Ali SMS, Iqbal MF, Haseeb A · Irish journal of medical science · 2024-02-05

Observational human study

180. The Assessment of the Efficacy, Safety, and Challenges of Ketogenic Diet Therapy in Children with Epilepsy: The First Experience of a Single Center.

Karandienė J, Endzinienė M, Liaušienė K, Jurkevičienė G · Medicina (Kaunas, Lithuania) · 2024-05-31

Preclinical / mechanistic

181. A novel hepatocyte ketone production assay to help the selection of nutrients for the ketogenic diet treatment of epilepsy.

Meeusen H, Romagnolo A, Holsink SAC, van den Broek TJM, van Helvoort A, Gorter JA, van Vliet EA, Verkuyl JM, Silva JP, Aronica E · Scientific reports · 2024-05-24

Systematic review / meta-analysis

182. ADCY3: the pivotal gene in classical ketogenic diet for the treatment of epilepsy.

Lin M, Gong J, Wu L, Lin X, Zhang Y, Lin W, Huang H, Zhu C · Frontiers in cellular neuroscience · 2024-05-22

Other

183. Control of seizure-like dynamics in neuronal populations with excitability adaptation related to ketogenic diet.

Eydam S, Franović I, Kang L · Chaos (Woodbury, N.Y.) · 2023-10-13

Other

184. Drug-resistant epilepsy and ketogenic diet therapy - a qualitative study of families' experiences.

Carroll JH, Parkin T, Cross JH, Hickson M, Williams E, Aldridge V, Collinson A · Seizure · 2024-04-26

Other

185. Glutamate-reduced diet and ketogenic diet for pediatric drug-resistant epilepsy: a novel approach to treatment.

Mughal ZUN, Malik A, Rangwala BS, Rangwala HS, Fatima H, Ali M, Farah AA · Annals of medicine and surgery (2012) · 2024-03-18

Observational human study

186. Ketogenic diet therapy in children with epilepsy caused by SLC2A1 mutations: a single-center single-arm retrospective study.

Wang YY, Zhou YQ, Luo LJ, Wang CJ, Shen N, Li H, Wang JW · World journal of pediatrics : WJP · 2022-10-27

Other

187. Author Correction: Ketogenic diet-produced β-hydroxybutyric acid accumulates brain GABA and increases GABA/glutamate ratio to inhibit epilepsy.

Qiao YN, Li L, Hu SH, Yang YX, Ma ZZ, Huang L, An YP, Yuan YY, Lin Y, Xu W, Li Y, Lin PC, Cao J, Zhao JY, Zhao SM · Cell discovery · 2024-04-30

Review

188. Telemedicine for Ketogenic Dietary Treatment in Refractory Epilepsy and Inherited Metabolic Disease: State of Play and Future Perspectives.

Höller A, Welte S, Schönlaub AK, Uhlisch C, Scholl-Bürgi S, Male-Dressler A, Pfeifer B, Schreier G · Studies in health technology and informatics · 2024-04-29

Review

189. [Fourteenth Jesús Culebras Lecture. Ketogenic diet, a half-discovered treatment].

Pedrón Giner CC · Nutricion hospitalaria · 2024-04-26

Review

190. Drug resistant epilepsy and ketogenic diet: A narrative review of mechanisms of action.

Mishra P, Singh SC, Ramadass B · World neurosurgery: X · 2024-02-25

Clinical trial / intervention

191. Tolerance, adherence, and acceptability of a ketogenic 2.5:1 ratio, nutritionally complete, medium chain triglyceride-containing liquid feed in children and adults with drug-resistant epilepsy following a ketogenic diet.

Griffen C, Schoeler NE, Browne R, Cameron T, Kirkpatrick M, Thowfeek S, Munn J, Champion H, Mills N, Phillips S, Air L, Devlin A, Nicol C, Macfarlane S, Bittle V, Thomas P, Cooke L, Ackril J, Allford A, Appleyard V, Szwec C, Atwal K, Hubbard GP, Stratton RJ · Epilepsia open · 2024-02-27

Other

192. Response to "Pediatric refractory epilepsy: Exploring the ketogenic diet's influence on seizure recurrence".

Zhang Y, Li Y, Ni Y, Gong X, Lu Z, Zhou Y, Wang Y, Yu L, Zhou S · Epileptic disorders : international epilepsy journal with videotape · 2024-02-09

Other

193. Pediatric refractory epilepsy: Exploring the ketogenic diet's influence on seizure recurrence.

Panda PK, Sharawat IK · Epileptic disorders : international epilepsy journal with videotape · 2024-02-06

Case report / case series

194. ATN1-related infantile developmental and epileptic encephalopathy responding to Ketogenic diet.

Xie Y, Su T, Liu Y, Xu S · Seizure · 2024-01-19

Observational human study

195. Long-term effectiveness and tolerability of ketogenic diet therapy in patients with genetic developmental and epileptic encephalopathy onset within the first 6 months of life.

Song T, Deng J, Chen C, Wang X, Han T, Wang X, Fang T, Tian X, Fang F · Epilepsia open · 2024-01-18

Case report / case series

196. GLUT-1DS resistant to ketogenic diet: from clinical feature to in silico analysis. An exemplificative case report with a literature review.

Falsaperla R, Sortino V, Vitaliti G, Privitera GF, Ruggieri M, Fusto G, Pappalardo XG · Neurogenetics · 2024-01-08

Clinical trial / intervention

197. A Ketogenic Diet may Improve Cognitive Function in Rats with Temporal Lobe Epilepsy by Regulating Endoplasmic Reticulum Stress and Synaptic Plasticity.

Qiao Q, Tian S, Zhang Y, Che L, Li Q, Qu Z, Wang W · Molecular neurobiology · 2023-10-23

Clinical trial / intervention

198. Ketogenic dietary therapy utilization in Kenya: A qualitative exploration of dietitian's perceptions.

Samia P, Naanyu V, Helen Cross J, Idro R, Boon P, Wilmshurst J, Luchters S · Epilepsy & behavior reports · 2024-03-20

Case report / case series

199. Experience with the Ketogenic Diet in a Boy with CLCN4 Related Neurodevelopmental Disorder.

Sager G, Yukselmis U, Güzel O, Turkyilmaz A, Akcay M · Balkan journal of medical genetics : BJMG · 2024-03-12

Systematic review / meta-analysis

200. Effect of the ketogenic diet as a treatment for refractory epilepsy in children and adolescents: a systematic review of reviews.

Díez-Arroyo C, García-García M, Soto-Méndez MJ, Molina-Montes E, Gil-Campos M, Gil Á, Gutiérrez-Jimeno M, Hernández-Ruiz Á · Nutrition reviews · 2024-03-12

Other

201. Efficacy and safety of modified medium-chain triglyceride ketogenic diet in patients with drug-resistant epilepsy.

Li H, Wang Y, Guo J, Zhang P, Xu Z, Peng K, Dong X, Zhao L · Acta epileptologica · 2024-03-06

Preclinical / mechanistic

202. The Unconventional Effects of the Ketogenic Diet (KD) in Preclinical Epilepsy.

Simeone T, Simeone K · Epilepsy currents · 2024-01-10

Preclinical / mechanistic

203. Assessment of a one-week ketogenic diet on brain glycolytic metabolism and on the status epilepticus stage of a lithium-pilocarpine rat model.

Doyen M, Lambert C, Roeder E, Boutley H, Chen B, Pierson J, Verger A, Raffo E, Karcher G, Marie PY, Maskali F · Scientific reports · 2024-03-01

Review

204. Role of ketogenic diet in neurodegenerative diseases focusing on Alzheimer diseases: The guardian angle.

Al-Kuraishy HM, Jabir MS, Albuhadily AK, Al-Gareeb AI, Jawad SF, Swelum AA, Hadi NR · Ageing research reviews · 2024-02-14

Other

205. Ketogenic diet for epilepsy and obesity: Is it the same?

Tagliabue A, Armeno M, Berk KA, Guglielmetti M, Ferraris C, Olieman J, van der Louw E · Nutrition, metabolism, and cardiovascular diseases : NMCD · 2024-01-14

Clinical trial / intervention

206. The impact of microbiota and ketogenic diet interventions in the management of drug-resistant epilepsy.

Diaz-Marugan L, Rutsch A, Kaindl AM, Ronchi F · Acta physiologica (Oxford, England) · 2024-02-05

Systematic review / meta-analysis

207. Ketogenic diets: A systematic review of current scientific evidence and possible applicability in dogs and cats.

Vendramini THA, Amaral AR, Rentas MF, Nogueira JPDS, Pedrinelli V, de Oliveira VV, Zafalon RVA, Brunetto MA · Journal of animal physiology and animal nutrition · 2023-12-13

Systematic review / meta-analysis

208. Keto Clarity: A Comprehensive Systematic Review Exploring the Efficacy, Safety, and Mechanisms of Ketogenic Diet in Pediatric Epilepsy.

Faheem Y, Jaiswal A, Shergill K, Boppana K, Almansouri NE, Bakkannavar S, Yu AK · Cureus · 2024-02-25

Preclinical / mechanistic

209. Ketogenic diet-produced β-hydroxybutyric acid accumulates brain GABA and increases GABA/glutamate ratio to inhibit epilepsy.

Qiao YN, Li L, Hu SH, Yang YX, Ma ZZ, Huang L, An YP, Yuan YY, Lin Y, Xu W, Li Y, Lin PC, Cao J, Zhao JY, Zhao SM · Cell discovery · 2024-02-13

Clinical trial / intervention

210. Ketogenic diet in pharmacoresistant epilepsies: a clinical nutritional assessment.

Mendonça CN, Henriques-Souza AMM, Viana LA, Souza PA, Alves Neto LB, Mello MJG · Arquivos de neuro-psiquiatria · 2024-02-23

Clinical trial / intervention

211. Efficacy and safety of a smartphone application-based treatment of ketogenic diet in pediatric refractory epilepsy.

Li W, Gu W, Liang C, Tu F, Ding L, Lu X, Guo H, Zheng G, Wu C · Epilepsia open · 2023-12-21

Observational human study

212. Use of ketogenic dietary therapy for drug-resistant epilepsy in early infancy.

Armeno M, Calligaris S, Gagiulo D, Cresta A, Vaccarezza MM, Diez CG, Alberti MJ, Viollaz R, Vilavedra F, Caraballo RH · Epilepsia open · 2023-11-20

Other

213. Retracted: Curative Effect of Prebiotics/Probiotics-Assisted Ketogenic Diet on Children with Refractory Epilepsy.

International EM · Emergency medicine international · 2024-01-24

Observational human study

214. Hypocarnitinemia and its effect on seizure control in adult patients with intractable epilepsy on the modified Atkins diet.

Chu DY, Ravelli MN, Faltersack KM, Woods AL, Almane D, Li Z, Sampene E, Felton EA · Frontiers in nutrition · 2024-01-05

Other

215. Ketogenic Diet: Parental Experiences and Expectations.

Orr E, Whitney R, Nandeesha N, Kossoff EH, RamachandranNair R · Journal of child neurology · 2024-02-05

Review

216. Risks of the ketogenic diet in CKD - the con part.

Joshi S, Shi R, Patel J · Clinical kidney journal · 2023-11-07

Other

217. Evaluating the efficacy of a ketogenic diet in managing drug resistant paediatric DEDPC5-related epilepsy.

Winczewska-Wiktor A, Braszka M, Harada-Laszlo M, Badura-Stronka M, Kaczmarek I, Starczewska M, Wencel-Warot A, Steinborn B, Jamsheer A · Epilepsy & behavior : E&B · 2023-12-19

Review

218. Is ketogenic diet a 'precision medicine'? Recent developments and future challenges.

Falsaperla R, Sortino V, Striano P, Kluger G, Ramantani G, Ruggieri M, Network for Therapy in Rare Epilepsies (NETRE) · European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society · 2023-11-15

Other

219. Corrigendum to: Glutathione Increase and Seizure Burden Decrease in Patients with Intractable Epilepsy on Ketogenic Diet.

Hazany S, DeClouette B, Lowe J, Hwang DH, Kim PE, Bluml S, Partikian A · Journal of epilepsy research · 2023-12-31

Randomized clinical trial

220. The Effectiveness of Modified Atkins Ketogenic Diet on Children with Intractable Epilepsy: A Pilot Study from Indonesia.

Rafli A, Handryastuti S, Karyanti MR, Devaera Y, Hafifah CN, Mangunatmadja I, Kadim M, Herini ES, Nofi LS, Ratnawati A, Fitrianti S · Journal of nutrition and metabolism · 2023-12-29

Preclinical / mechanistic

221. Fecal transfers from children on the ketogenic diet mimic the anti-seizure effect in mice.

Prast-Nielsen S · Cell reports · 2023-12-08

Preclinical / mechanistic

222. Ketogenic diet therapy for pediatric epilepsy is associated with alterations in the human gut microbiome that confer seizure resistance in mice.

Lum GR, Ha SM, Olson CA, Blencowe M, Paramo J, Reyes B, Matsumoto JH, Yang X, Hsiao EY · Cell reports · 2023-12-08

Other

223. Predictors of elevations in fasting lipid levels in adults with epilepsy on a modified Atkins diet.

McDonald TJW, Diaz-Arias L, Vizthum D, Henry-Barron BJ, Cervenka MC · Seizure · 2023-11-21

Randomized clinical trial

224. Classic ketogenic diet versus further antiseizure medicine in infants with drug-resistant epilepsy (KIWE): a UK, multicentre, open-label, randomised clinical trial.

Schoeler NE, Marston L, Lyons L, Halsall S, Jain R, Titre-Johnson S, Balogun M, Heales SJR, Eaton S, Orford M, Neal E, Reilly C, Eltze C, Stephen E, Mallick AA, O'Callaghan F, Agrawal S, Parker A, Kirkpatrick M, Brunklaus A, McLellan A, McCullagh H, Samanta R, Kneen R, Tan HJ, Devlin A, Prasad M, Rattihalli R, Basu H, Desurkar A, Williams R, Fallon P, Nazareth I, Freemantle N, Cross JH, KIWE study group · The Lancet. Neurology · 2023-06-26

Review

225. Propofol for Anesthesia in Pediatric Patients With Epilepsy on the Ketogenic Diet: A Single-Center Experience.

Bui PH, Handoko M, Diaz-Medina G, Ng AS, Katyayan A · Pediatric neurology · 2023-08-25

Preclinical / mechanistic

226. A novel de novo HCN2 loss-of-function variant causing developmental and epileptic encephalopathy treated with a ketogenic diet.

DiFrancesco JC, Ragona F, Murano C, Frosio A, Melgari D, Binda A, Calamaio S, Prevostini R, Mauri M, Canafoglia L, Castellotti B, Messina G, Gellera C, Previtali R, Veggiotti P, Milanesi R, Barbuti A, Solazzi R, Freri E, Granata T, Rivolta I · Epilepsia · 2023-10-07

Other

227. Long-term effectiveness and seizure recurrence risk factors of ketogenic diet for pediatric refractory epilepsy: Experience from a tertiary care center in China.

Zhang Y, Li Y, Ni Y, Gong X, Lu Z, Zhou Y, Wang Y, Yu L, Zhou S · Epileptic disorders : international epilepsy journal with videotape · 2023-09-23

Observational human study

228. Feasibility, tolerability and efficacy of the ketogenic diet in children with drug-resistant epilepsy in Vietnam.

Nguyen TMT, Jallon P, Korff C, Nguyen H, Nguyen The Tich S · Epilepsia open · 2023-10-03

Observational human study

229. Stress biomarkers in adult patients with drug-resistant epilepsy on a modified Atkins diet: A prospective study.

Molteberg E, Thorsby PM, Kverneland M, Iversen PO, Selmer KK, Hofoss D, Nakken KO, Taubøll E · Epilepsia open · 2023-09-13

Randomized clinical trial

230. Impact of two ketogenic diet types in refractory childhood epilepsy.

El-Shafie AM, Bahbah WA, Abd El Naby SA, Omar ZA, Basma EM, Hegazy AAA, El Zefzaf HMS · Pediatric research · 2023-03-11

Systematic review / meta-analysis

231. Modified Atkins diet for drug-resistant epilepsy: A systematic review and meta-analysis of randomized controlled trials.

Mutarelli A, Nogueira A, Felix N, Godoi A, Dagostin CS, Castro LHM, Mota Telles JP · Seizure · 2023-09-12

Other

232. Ketogenic Diets in Children With Intractable Epilepsy and its Effects on Gastrointestinal Function, Gut Microbiome, Inflammation, and Quality of Life.

Menzies J, Sundararaj A, Cardamone M, McHarg A, Leach S, Krishnan U · Journal of pediatric gastroenterology and nutrition · 2023-09-08

Preclinical / mechanistic

233. Ketogenic diet influence on the elemental homeostasis of internal organs is gender dependent.

Kawon K, Rugiel M, Setkowicz Z, Matusiak K, Kubala-Kukus A, Stabrawa I, Szary K, Rauk Z, Chwiej J · Scientific reports · 2023-10-27

Other

234. Changes in lipids and inflammation in adults with super-refractory status epilepticus on a ketogenic diet.

Dickens AM, Johnson TP, Lamichhane S, Kumar A, Pardo CA, Gutierrez EG, Haughey N, Cervenka MC · Frontiers in molecular biosciences · 2023-10-23

Other

235. [Optimizing carbohydrate intake from drugs in epileptic patients on a ketogenic diet].

Corazón Villanueva J, de la Torre Ortíz M, Puebla García V, Martínez Sesmero JM · Nutricion hospitalaria · 2023-10-09

Randomized clinical trial

236. The Modified Atkins Diet for Epilepsy: Two Decades of an "Alternative" Ketogenic Diet Therapy.

Kossoff EH · Pediatric neurology · 2023-07-22

Other

237. The efficacy of a medium-chain triglyceride ketogenic diet for drug-resistant epilepsy with PIGA germline variant.

Ikeda A, Nagafuchi H, Enomoto Y, Kurosawa K, Tsuyusaki Y, Tsuji M, Goto T · Seizure · 2023-08-07

Observational human study

238. Ketogenic Diet in Neonates with Drug-Resistant Epilepsy: Efficacy and Side Effects-A Single Center's Initial Experience.

Falsaperla R, Sortino V, Collotta AD, Privitera GF, Palmeri A, Mauceri L, Ruggieri M · Neuropediatrics · 2023-06-15

Other

239. Kidney Stones in Epileptic Children Receiving Ketogenic Diet: Frequency and Risk Factors.

Güzin Y, Yılmaz Ü, Devrim F, Dinçel N, Ünalp A · Neuropediatrics · 2023-05-31

Randomized clinical trial

240. Modified Atkins Diet vs. Ketogenic Diet in the Management of Children with Epileptic Spasms Refractory to First Line Treatment: An Open Labelled, Randomized Controlled Trial.

Sharma S, Dabla S, Kaushik JS · Indian journal of pediatrics · 2023-05-26

Systematic review / meta-analysis

241. Ketogenic Diet and Multiple Health Outcomes: An Umbrella Review of Meta-Analysis.

Chen S, Su X, Feng Y, Li R, Liao M, Fan L, Liu J, Chen S, Zhang S, Cai J, Zhu S, Niu J, Ye Y, Lo K, Zeng F · Nutrients · 2023-09-27

Guideline / consensus

242. Parenteral medication considerations for the ketogenic diet.

Abu-Sawwa R, Busque K, Cokley J · American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists · 2023-09-25

Observational human study

243. Effect of a ketogenic diet on decrease of seizures in refractory epilepsy among children (infancy to 14 years old) in Saudi Arabia: a cross-sectional study.

Baghdadi LR, Alhomaidi RA, Alhelal FS, Alqahtani AA, Aldosary SA, Almohammedi SM, Almutairi RA, Jad LA, AlShammari HH · Translational pediatrics · 2023-08-29

Preclinical / mechanistic

244. Safe use of the ketogenic diet in an infant with microcephaly, epilepsy, and diabetes syndrome: a case report.

Zegarra WA, Gallentine WB, Ruzhnikov MR, McAndrews CA, Gloyn AL, Addala A · BMC pediatrics · 2023-09-09

Observational human study

245. Feasibility of ketogenic diet therapy variants for refractory epilepsy in neonates to infants under 2 years old.

Hsieh TY, Su TY, Hung KY, Hsu MS, Lin YJ, Kuo HC, Hung PL · Epilepsy & behavior : E&B · 2023-08-05

Observational human study

246. Factors Associated With Growth in Patients Treated With the Classic Ketogenic Diet for Drug-Resistant Epilepsy.

Thompson L, Sullivan DK, Varghese K, Abdelmoity A, Malik M, Abdelmoity A, Hall A · Pediatric neurology · 2023-06-21

Other

247. Dynamics of glucose concentration during the initiation of ketogenic diet treatment in children with refractory epilepsy: Results of continuous glucose monitoring.

Brožová K, Michalec J, Brabec M, Bořilová P, Kohout P, Brož J · Epilepsia open · 2023-07-04

Clinical trial / intervention

248. Decreased serum concentrations of antiseizure medications in children with drug resistant epilepsy following treatment with ketogenic diet.

Pedersen S, Kverneland M, Rudi K, Gervin K, Landmark CJ, Iversen PO, Selmer KK · Epilepsia open · 2023-05-09

Review

249. The place of a ketogenic diet in the treatment of resistant epilepsy: a comprehensive review.

Cicek E, Sanlier N · Nutritional neuroscience · 2022-07-05

Clinical trial / intervention

250. Microbiota-gut-brain axis and ketogenic diet: how close are we to tackling epilepsy?

Mengoli M, Conti G, Fabbrini M, Candela M, Brigidi P, Turroni S, Barone M · Microbiome research reports · 2023-08-29

Other

251. Validation of an Italian Questionnaire of Adherence to the Ketogenic Dietary Therapies: iKetoCheck.

Lopes Neri LC, Guglielmetti M, De Giorgis V, Pasca L, Zanaboni MP, Trentani C, Ballante E, Grumi S, Ferraris C, Tagliabue A, On Behalf Of The KDTs Delphi Validation Study Group · Foods (Basel, Switzerland) · 2023-08-26

Preclinical / mechanistic

252. Does Ketogenic Diet Used in Pregnancy Affect the Nervous System Development in Offspring?─FTIR Microspectroscopy Study.

Rugiel M, Setkowicz-Janeczko Z, Kosiek W, Rauk Z, Kawon K, Chwiej J · ACS chemical neuroscience · 2023-07-20

Review

253. Modified Atkins diet in children with epilepsy with eyelid myoclonia (Jeavons syndrome).

Paibool W, Schimpf S, Nordli DR, Phitsanuwong C · Epilepsy & behavior : E&B · 2023-07-16

Observational human study

254. A case-control evaluation of Spasm control and Tolerability of the Modified Atkins diet versus classic ketogenic diet in Chinese Children with infantile epileptic spasms syndrome.

Dou X, Jia S, Wang Z, Wang Y, Wu F, Wu Y, Niu M, Li X, Wang D · Seizure · 2023-07-07

Preclinical / mechanistic

255. Intermittent vs continuous ketogenic diet: Impact on seizures, gut microbiota, and mitochondrial metabolism.

Shearer J, Scantlebury MH, Rho JM, Tompkins TA, Mu C · Epilepsia · 2023-06-29

Other

256. Patient and carer perspectives on the use of video consultations in the management of the ketogenic diet for epilepsy.

Bara VB, Schoeler N, Carroll JH, Simpson Z, Cameron T, Ketogenic Dietitians Research Network KDRN · Epilepsy & behavior : E&B · 2023-06-12

Review

257. Effects of very low carbohydrate ketogenic diets on skeletal health.

Best CM, Hsu S · Current opinion in endocrinology, diabetes, and obesity · 2023-05-02

Other

258. Ketonemia variability through menstrual cycle in patients undergoing classic ketogenic diet.

Pasca L, Ferraris C, Guglielmetti M, Varesio C, Totaro M, Trentani C, Marazzi C, Brambilla I, Ballante E, Armeno M, Valenzuela GR, Caraballo RH, Veggiotti P, Tagliabue A, De Giorgis V · Frontiers in nutrition · 2023-07-27

Other

259. Ketogenic diet in childhood epilepsy: clinical algorithm in a tertiary care center.

Shaaban S, Al-Beltagi M, El Rashidy O, Nassar M, El Gendy Y · Frontiers in pediatrics · 2023-07-06

Case report / case series

260. Early Infantile Epileptic Encephalopathy In Asparagine-Linked Glycosylation Thirteen (ALG13) Gene Defect And Dramatic Response With Ketogenic Diet.

Chand P, Sulaiman A, Angez M, Kirmani S · JPMA. The Journal of the Pakistan Medical Association · 2023-07-21

Randomized clinical trial

261. Utilization of the ketogenic diet for adults with status epilepticus.

Teixeira FJP, Shannon J, Busl KM, Robinson CP, Ahmed B, Katz J, Miao G, Seckar J, Bruzzone M, Cervenka MC, Maciel CB · Epilepsy & behavior : E&B · 2023-06-02

Observational human study

262. Difficulties in the implementation of the ketogenic diet in adult patients with refractory epilepsy.

Erkent I, Ilgaz F, Dericioglu N · Epilepsy & behavior : E&B · 2023-05-14

Case report / case series

263. Ketogenic diet-responsive drug-resistant epilepsy in a case of asparagine synthetase deficiency with a novel compound heterozygous missense variant.

Altıntaş M, Yıldırım M, Uçar Çİ, Köse E, Bektaş Ö, Teber S · Clinical neurology and neurosurgery · 2023-05-08

Observational human study

264. Brain Glutathione Increase and Seizure Burden Decrease in Patients with Intractable Epilepsy on Ketogenic Diet.

Hazany S, DeClouette B, Lowe J, Hwang DH, Kim PE, Bluml S, Partikian A · Journal of epilepsy research · 2023-06-30

Observational human study

265. Correction to "genome-wide decrease in DNA methylation in adults with epilepsy treated with modified ketogenic diet: A prospective study".

Epilepsia · 2023-04-27

Observational human study

266. Role of EEG as a monitoring tool in patients with glucose transporter type I deficiency syndrome (GLUT1-DS) on ketogenic diet.

Toro-Perez J, Healy S, Sell E, Bulusu S, Whiting S · Epileptic disorders : international epilepsy journal with videotape · 2023-05-06

Clinical trial / intervention

267. The ketogenic diet for Dravet syndrome: A multicenter retrospective study.

Yu M, Li H, Sun D, Li D, Zhong J, Gu Q, Huang S, Luo R, Zhu D, Yuan B, Li B, Xiao N, Chen Y, Zhang Y, Wei J, Jiang Y, Liao J, Qin J, China Association Against Epilepsy Ketogenic Diet Group · Nutrition (Burbank, Los Angeles County, Calif.) · 2023-02-12

Case report / case series

268. Ketogenic Diet Attenuates Refractory Epilepsy of Harel-Yoon Syndrome With ATAD3A Variants: A Case Report and Review of Literature.

Chen Y, Rong S, Luo H, Huang B, Hu F, Chen M, Li C · Pediatric neurology · 2023-03-09

Randomized clinical trial

269. The Relationship of Ketogenic Diet with Neurodegenerative and Psychiatric Diseases: A Scoping Review from Basic Research to Clinical Practice.

Mentzelou M, Dakanalis A, Vasios GK, Gialeli M, Papadopoulou SK, Giaginis C · Nutrients · 2023-05-11

Randomized clinical trial

270. Keto Is Not Just for Kids: A Randomized Trial of a Modified Atkins Diet for Adolescents and Adults With Anti-Seizure Medication-Resistant Epilepsy.

Cervenka MC · Epilepsy currents · 2023-03-05

Other

271. Ketogenic diet in children and adolescents: The effects on growth and nutritional status.

Corsello A, Trovato CM, Di Profio E, Cardile S, Campoy C, Zuccotti G, Verduci E, Diamanti A · Pharmacological research · 2023-04-22

Randomized clinical trial

272. Health-related quality of life in adults with drug-resistant focal epilepsy treated with modified Atkins diet in a randomized clinical trial.

Kverneland M, Nakken KO, Hofoss D, Skogan AH, Iversen PO, Selmer KK, Lossius MI · Epilepsia · 2023-03-29

Case report / case series

273. Choice of pharmaceutical form as a key factor during ketogenic diet: a case report.

Rodríguez-Ramallo H, Báez-Gutiérrez N, Valverde Fernandez J, Araujo-Rodríguez FJ · European journal of hospital pharmacy : science and practice · 2021-06-08

Observational human study

274. A Review of Ketogenic Dietary Therapies for Epilepsy and Neurological Diseases: A Proposal to Implement an Adapted Model to Include Healthy Mediterranean Products.

Ferraris C, Guglielmetti M, Neri LCL, Allehdan S, Mohsin Albasara JM, Fareed Alawadhi HH, Trentani C, Perna S, Tagliabue A · Foods (Basel, Switzerland) · 2023-04-22

Observational human study

275. Comprehensive study of metabolic changes induced by a ketogenic diet therapy using GC/MS- and LC/MS-based metabolomics.

Akiyama M, Akiyama T, Saigusa D, Hishinuma E, Matsukawa N, Shibata T, Tsuchiya H, Mori A, Fujii Y, Mogami Y, Tokorodani C, Kuwahara K, Numata-Uematsu Y, Inoue K, Kobayashi K · Seizure · 2023-03-16

Other

276. Metabolomic, proteomic, and transcriptomic changes in adults with epilepsy on modified Atkins diet.

Leitner DF, Siu Y, Korman A, Lin Z, Kanshin E, Friedman D, Devore S, Ueberheide B, Tsirigos A, Jones DR, Wisniewski T, Devinsky O · Epilepsia · 2023-02-24

Other

277. Use of Ketogenic Diet in Two Indian Children with a Rare Early-Onset Epileptic Encephalopathy.

Gunasekaran PK, Laxmi V, Bilamge A, Saini L · Indian journal of pediatrics · 2023-02-02

Randomized clinical trial

278. Safety, Efficacy, and Tolerability of Modified Atkins Diet in Persons With Drug-Resistant Epilepsy: A Randomized Controlled Trial.

Manral M, Dwivedi R, Gulati S, Kaur K, Nehra A, Pandey RM, Upadhyay AD, Sapra S, Tripathi M · Neurology · 2023-01-04

Other

279. Effect of a Ketogenic Medium Chain Triglyceride-Enriched Diet on the Fecal Microbiota in Canine Idiopathic Epilepsy: A Pilot Study.

García-Belenguer S, Grasa L, Palacio J, Moral J, Rosado B · Veterinary sciences · 2023-03-24

Other

280. The effects of ketogenic diet on beta-hydroxybutyrate, arachidonic acid, and oxidative stress in pediatric epilepsy.

Poorshiri B, Barzegar M, Afghan M, Shiva S, Shahabi P, Golchinfar Z, Yousefi Nodeh HR, Raeisi S · Epilepsy & behavior : E&B · 2023-02-04

Other

281. Experience with the ketogenic diet in premature neonates.

Phitsanuwong C, Kim JA, Schimpf S, Nordli DR · Epilepsia open · 2022-12-01

Observational human study

282. Antiseizure medication reduction and withdrawal in children with drug-resistant epilepsy after starting the ketogenic diet.

Gogou M, Pujar S, Nemani T, Chiang C, Simpson Z, Hardy I, Schoeler N, Cross JH, Eltze C · Developmental medicine and child neurology · 2022-08-15

Case report / case series

283. Impressive efficacy of the ketogenic diet in a KCNQ2 encephalopathy infant: a case report and exhaustive literature review.

Falsaperla R, Marino SD, Salomone G, Madia F, Marino S, Tardino LG, Scalia B, Ruggieri M · Translational pediatrics · 2023-01-16

Other

284. The Ketogenic Diet in Children with Epilepsy: A Focus on Parental Stress and Family Compliance.

Operto FF, Labate A, Aiello S, Perillo C, de Simone V, Rinaldi R, Coppola G, Pastorino GMG · Nutrients · 2023-02-20

Observational human study

285. Ketogenic diet for epilepsy control and enhancement in adaptive behavior.

El-Rashidy OF, Nassar MF, Shokair WA, El Gendy YGA · Scientific reports · 2023-02-06

Systematic review / meta-analysis

286. Let food be thy medicine. The interaction between ketogenic diet therapy and anti-seizure medications: A systematic review.

Armeno ML, Kossoff EH · Epileptic disorders : international epilepsy journal with videotape · 2023-04-17

Observational human study

287. Impact of ketogenic diet therapy on growth in children with epilepsy.

Lu S, Champion H, Mills N, Simpson Z, Whiteley VJ, Schoeler NE · Epilepsy research · 2023-01-06

Review

288. Does the ketogenic ratio matter when using ketogenic diet therapy in pediatric epilepsy?

Sharma S, Whitney R, Kossoff EH, RamachandranNair R · Epilepsia · 2022-12-15

Observational human study

289. Efficacy, Retention Rate, and Influencing Factors of Ketogenic Diet Therapy in Children with Refractory Epilepsy: A Retrospective Study.

Shen J, Jiang T, Gao F, Jiang K · Neuropediatrics · 2022-09-13

Review

290. Ketogenic Diet and Ketone Bodies against Ischemic Injury: Targets, Mechanisms, and Therapeutic Potential.

Makievskaya CI, Popkov VA, Andrianova NV, Liao X, Zorov DB, Plotnikov EY · International journal of molecular sciences · 2023-01-30

Clinical trial / intervention

291. Long-term outcomes of infantile spasms in children treated with ketogenic diet therapy in combination with anti-seizure medications in a resource-limited region.

Liao J, Hu Z, Lin S, Lu X, Wen J, Duan J, Zou D, Zou H, Yu M, Liu L, Qiao X, Ye Y · Frontiers in epidemiology · 2023-01-16

Case report / case series

292. [Oral desensitization with Ketocal® in an infant with ketogenic diet and cow's milk protein allergy].

Benítez Provedo C, Martínez Ibeas MA, Losada Del Pozo R, Montes Arjona AM, Blanco Rodríguez M, Del Río Camacho G · Nutricion hospitalaria · 2022-10-18

Randomized clinical trial

293. Intractable Seizures in Children With Type 1 Diabetes: Implications of the Ketogenic Diet.

Vidmar KK, Pollock AJ · WMJ : official publication of the State Medical Society of Wisconsin · 2023-01-13

Clinical trial / intervention

294. Fat not so bad? The role of ketone bodies and ketogenic diet in the treatment of endothelial dysfunction and hypertension.

Pirola L, Ciesielski O, Balcerczyk A · Biochemical pharmacology · 2022-11-13

Other

295. Corrigendum to "Gut flora and metabolism are altered in epilepsy and partially restored after ketogenic diets" [Microb. Pathog. 155 (2021) 104899].

Gong X, Cai Q, Liu X, An D, Zhou D, Luo R, Peng R, Hong Z · Microbial pathogenesis · 2022-10-26

Randomized clinical trial

296. Modified Atkins diet versus levetiracetam for non-surgical drug-resistant epilepsy in children: A randomized open-label study.

Archna, Garg D, Goel S, Mukherjee SB, Pemde HK, Jain P, Sharma S · Seizure · 2022-10-14

Observational human study

297. Research Involvement in a Group of Registered Dietitian Nutritionists Specializing in Ketogenic Diet Therapies for Epilepsy.

Lowe J, Brown J, Klier K, White JD, Briceno Alliegro L, Sewak S, Mele-Hayes D · Journal of the Academy of Nutrition and Dietetics · 2022-05-17

Review

298. Ketogenic Diets in the Management of Lennox-Gastaut Syndrome-Review of Literature.

Skrobas U, Duda P, Bryliński Ł, Drożak P, Pelczar M, Rejdak K · Nutrients · 2022-11-23

Observational human study

299. Tolerance and response to ketogenic therapy in neonates and infants younger than 4 months. Case series in a hospital center in Medellin, Colombia.

Serrano-Tabares C, Trujillo-Gómez J, Morales-Gil RM, Aguilar-Pérez Y, Jiménez-Villegas MJ · Revista de neurologia · 2022-11-10

Systematic review / meta-analysis

300. Effect of the modified Atkins diet in adults with drug-resistant epilepsy: A controlled study.

Quiroga-Padilla PJ, Briceño C, Mayor LC · Epilepsy & behavior : E&B · 2022-10-07

Review

301. Modified low ratio ketogenic therapy in the treatment of adults with super-refractory status epilepticus.

Kaul N, Nation J, Laing J, Nicolo JP, Deane AM, Udy AA, Kwan P, O'Brien TJ · JPEN. Journal of parenteral and enteral nutrition · 2022-04-07

Other

302. Graph Theory-Based Electroencephalographic Connectivity via Phase-Locking Value and Its Association with Ketogenic Diet Responsiveness in Patients with Focal Onset Seizures.

Hsieh TY, Hung PL, Su TY, Peng SJ · Nutrients · 2022-10-23

Systematic review / meta-analysis

303. Efficacy of ketogenic diet in CDKL5-related epilepsy: a single arm meta-analysis.

Zhang J, Ma J, Chang X, Wu P, Li S, Wu Y · Orphanet journal of rare diseases · 2022-10-23

Clinical trial / intervention

304. The Efficacy of the Ketogenic Diet in Improving Seizures and EEG Findings in Patients with Refractory Infantile Spasms.

Hanifiha M, Shervin Badv R, Mahmoudi M, Tavasoli AR · Iranian journal of child neurology · 2022-10-23

Systematic review / meta-analysis

305. Modified Atkins diet versus ketogenic diet in children with drug-resistant epilepsy: A meta-analysis of comparative studies.

Mhanna A, Mhanna M, Beran A, Al-Chalabi M, Aladamat N, Mahfooz N · Clinical nutrition ESPEN · 2022-09-10

Observational human study

306. Effects of the ketogenic diet therapy in patients with STXBP1-related encephalopathy.

Nam JY, Teng LY, Cho K, Kang HC, Lee JS, Kim HD, Kim SH · Epilepsy research · 2022-08-01

Clinical trial / intervention

307. The effect of ketogenic diet escalation in adolescents and adults with drug-resistant epilepsy: a prospective study.

Kishk NA, Yousof HZ, Ebraheim AM, Elkholy TAFA, Soliman SH, Mohammed RA, Shamloul RM · Nutritional neuroscience · 2021-05-20

Preclinical / mechanistic

308. Ketogenic Diet Alleviates Hippocampal Neurodegeneration Possibly via ASIC1a and the Mitochondria-Mediated Apoptotic Pathway in a Rat Model of Temporal Lobe Epilepsy.

Qiao Q, Qu Z, Tian S, Cao H, Zhang Y, Sun C, Jia L, Wang W · Neuropsychiatric disease and treatment · 2022-09-25

Systematic review / meta-analysis

309. Ketogenic diet, epilepsy and cognition: what do we know so far? A systematic review.

Lima MC, Gabiatti MP, Moreira JD, Ribeiro LC, Lunardi MDS, Lin K, Venske DK · Nutrition reviews · 2022-05-11

Randomized clinical trial

310. Expanding Indications for a Ketogenic Diet as an Adjuvant Therapy in Adult Refractory Status Epilepticus: an Exploratory Study Using Moderation Analysis.

Koh S, Kim TJ, Shin HB, Kim HK, Park B, Moon SY, Kim BG, Huh K, Choi JY · Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2022-08-16

Other

311. Efficacy of the ketogenic diet in Chinese adults versus children with drug-resistant epilepsy: A pilot study.

He F, Qiu J, Li H, Guo H, Wang S, Ding Y, Xu S, Wang Z, Feng J, Zhang P, Ding M, Wang S · Epilepsy & behavior : E&B · 2022-07-13

Observational human study

312. Genome-wide decrease in DNA methylation in adults with epilepsy treated with modified ketogenic diet: A prospective study.

Pedersen S, Kverneland M, Nakken KO, Rudi K, Iversen PO, Gervin K, Selmer KK · Epilepsia · 2022-07-10

Preclinical / mechanistic

313. Ameliorating effect of ketogenic diet on acute status epilepticus: Insights into biochemical and histological changes in rat hippocampus.

Shehata NI, Abdelsamad MA, Amin HAA, Sadik NAH, Shaheen AA · Journal of food biochemistry · 2022-05-11

Systematic review / meta-analysis

314. Ketogenic diet for epilepsy: an overview of systematic review and meta-analysis.

Ruan Y, Chen L, She D, Chung Y, Ge L, Han L · European journal of clinical nutrition · 2022-01-13

Case report / case series

315. Benefits of ketogenic diet in a pediatric patient with Ehlers-Danlos syndrome and STXBP1-related epileptic encephalopathy.

Ünalp A, Gazeteci Tekin H, Karaoğlu P, Akışın Z · The International journal of neuroscience · 2020-12-09

Clinical trial / intervention

316. Ketogenic Diet Treatment of Defects in the Mitochondrial Malate Aspartate Shuttle and Pyruvate Carrier.

Bölsterli BK, Boltshauser E, Palmieri L, Spenger J, Brunner-Krainz M, Distelmaier F, Freisinger P, Geis T, Gropman AL, Häberle J, Hentschel J, Jeandidier B, Karall D, Keren B, Klabunde-Cherwon A, Konstantopoulou V, Kottke R, Lasorsa FM, Makowski C, Mignot C, O'Gorman Tuura R, Porcelli V, Santer R, Sen K, Steinbrücker K, Syrbe S, Wagner M, Ziegler A, Zöggeler T, Mayr JA, Prokisch H, Wortmann SB · Nutrients · 2022-08-31

Review

317. [Controlling carbohydrate content in antiepileptic medications for children on a ketogenic diet].

Martín Prado S, Pozas Del Río M, Cañedo Villarroya E, Pedrón Giner C · Nutricion hospitalaria · 2022-05-14

Guideline / consensus

318. The CORE-KDT study: a mixed methods protocol to establish core outcomes for refractory childhood epilepsy treated with ketogenic diet therapy.

Carroll JH, Cross JH, Hickson M, Williams E, Aldridge V, Collinson A · Trials · 2022-08-17

Other

319. Validation of ketogenic diet adherence questionnaire: Keto-check.

Neri LCL, Sampaio LPB · Arquivos de neuro-psiquiatria · 2022-10-17

Randomized clinical trial

320. Efficacy and Safety of the Ketogenic Diet for Mitochondrial Disease With Epilepsy: A Prospective, Open-labeled, Controlled Study.

Huang L, Li H, Zhong J, Yang L, Chen G, Wang D, Zheng G, Han H, Han X, Long Y, Wang X, Liang J, Yu M, Shen X, Fan M, Fang F, Liao J, Sun D · Frontiers in neurology · 2022-08-01

Other

321. Ketogenic diet for focal epilepsy with SPTAN1 encephalopathy.

Kishimoto K, Nabatame S, Kagitani-Shimono K, Kato M, Tohyama J, Nakashima M, Matsumoto N, Ozono K · Epileptic disorders : international epilepsy journal with videotape · 2022-08-04

Observational human study

322. Glycemic biomarkers in children with drug-resistant epilepsy on various types of ketogenic diet therapies: A cross-sectional study.

Teng LY, Lee VW, Murugesu S, Lee JX, Ibrahim NS, Ishak MF, Mohamed AR, Khoo TB · Epilepsia · 2022-05-23

Other

323. Effects of ketogenic diet on children with refractory epilepsy, electroencephalogram and neurobehavioral development.

Xing Y, Liu S, Lin Q · Minerva medica · 2020-12-18

Clinical trial / intervention

324. Western and ketogenic diets in neurological disorders: can you tell the difference?

Habashy KJ, Ahmad F, Ibeh S, Mantash S, Kobeissy F, Issa H, Habis R, Tfaily A, Nabha S, Harati H, Reslan MA, Yehya Y, Barsa C, Shaito A, Zibara K, El-Yazbi AF, Kobeissy FH · Nutrition reviews · 2022-02-17

Observational human study

325. Clinical implementation of ketogenic diet in children with drug-resistant epilepsy: Advantages, disadvantages, and difficulties.

Tong X, Deng Y, Liu L, Tang X, Yu T, Gan J, Cai Q, Luo R, Xiao N · Seizure · 2022-04-29

Clinical trial / intervention

326. Core outcome set development for childhood epilepsy treated with ketogenic diet therapy: Results of a scoping review and parent interviews.

Carroll JH, Martin-McGill KJ, Cross JH, Hickson M, Williams E, Aldridge V, Collinson A · Seizure · 2022-05-13

Preclinical / mechanistic

327. Increased Hippocampal Afterdischarge Threshold in Ketogenic Diet is Accompanied by Enhanced Kynurenine Pathway Activity.

Osuch B, Kołosowska K, Chmielewska N, Turzyńska D, Sobolewska A, Szyndler J, Maciejak P · Neurochemical research · 2022-05-06

Randomized clinical trial

328. Effect of a Ketogenic Diet on Oxidative Posttranslational Protein Modifications and Brain Homogenate Denaturation in the Kindling Model of Epilepsy in Mice.

Andreeva-Gateva P, Sabit Z, Bakalov D, Sayiner S, Tafradjiiska-Hadjiolova R, Zaharinova S, Abarova S, Koynova R, Tenchov B · Neurochemical research · 2022-03-22

Observational human study

329. Six-month effects of modified Atkins diet implementation on indices of cardiovascular disease risk in adults with epilepsy.

McDonald TJW, Diaz-Arias L, Vizthum D, Henry-Barron BJ, Schlechter H, Kossoff EH, Cervenka MC · Nutritional neuroscience · 2021-01-23

Clinical trial / intervention

330. Favorable response to classic ketogenic diet in a child with anti-GAD 65 antibody mediated super refractory status epilepticus.

Sivathanu D, Kewalramani D, Kumar Manokaran R · Epilepsy & behavior reports · 2022-06-07

Observational human study

331. Ketogenic dietary therapies for epilepsy: Experience in 160 patients over 18 years.

Ruiz Herrero J, Cañedo Villarroya E, García Peñas JJ, García Alcolea B, Gómez Fernández B, Puerta Macfarland LA, Pedrón-Giner C · Anales de pediatria · 2022-05-29

Clinical trial / intervention

332. Higher levels of Bifidobacteria and tumor necrosis factor in children with drug-resistant epilepsy are associated with anti-seizure response to the ketogenic diet.

Dahlin M, Singleton SS, David JA, Basuchoudhary A, Wickström R, Mazumder R, Prast-Nielsen S · EBioMedicine · 2022-05-19

Systematic review / meta-analysis

333. The Efficacy and Safety of Ketogenic Diets in Drug-Resistant Epilepsy in Children and Adolescents: a Systematic Review of Randomized Controlled Trials.

Desli E, Spilioti M, Evangeliou A, Styllas F, Magkos F, Dalamaga M · Current nutrition reports · 2022-03-18

Observational human study

334. Curative Effect of Prebiotics/Probiotics-Assisted Ketogenic Diet on Children with Refractory Epilepsy.

Su L, Li S, Sun B · Emergency medicine international · 2022-05-28

Randomized clinical trial

335. Addition of Prebiotics to the Ketogenic Diet Improves Metabolic Profile but Does Not Affect Seizures in a Rodent Model of Infantile Spasms Syndrome.

Mu C, Pochakom A, Reimer RA, Choudhary A, Wang M, Rho JM, Scantlebury MH, Shearer J · Nutrients · 2022-05-26

Observational human study

336. Ketogenic Diet Therapy for Drug-Resistant Epilepsy and Cognitive Impairment in Children With Tuberous Sclerosis Complex.

Fang Y, Li D, Wang M, Zhao X, Duan J, Gu Q, Li B, Zha J, Mei D, Bian G, Zhang M, Zhang H, Hu J, Yang L, Yu L, Li H, Liao J · Frontiers in neurology · 2022-05-24

Case report / case series

337. Keto-Bezoar: Adverse Event Related to Initiation of Ketogenic Diet in an Infant.

Stegall C, Evans MC, Hollinger LE, Walz AA · JPGN reports · 2022-02-25

Case report / case series

338. Positive impact of a modified Atkins diet on cognition, seizure control, and abnormal movements in an adult with glucose transporter type 1 deficiency syndrome: case report.

Diaz-Arias LA, Henry-Barron BJ, Buchholz A, Cervenka MC · Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2022-03-03

Case report / case series

339. Increase of Human Milk Fat Inducing Nutritional Ketosis in Exclusively Breastfed Infant, Brought About by Treating the Mother With Ketogenic Dietary Therapy.

Tan-Smith C, Little H, Fabe J, Dickson C, Shillito P · Journal of human lactation : official journal of International Lactation Consultant Association · 2021-10-05

Observational human study

340. Ketonuria and Seizure Control in the Medium Chain Triglyceride and Classic Ketogenic Diets.

Lowe H, Keller AE, Tanzini E, Aimola S, Liu YMC, Zak M, Chan V, Kobayashi J, Donner EJ · The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques · 2021-06-02

Clinical trial / intervention

341. Effects of Classic Ketogenic Diet in Children with Refractory Epilepsy: A Retrospective Cohort Study in Kingdom of Bahrain.

Perna S, Ferraris C, Guglielmetti M, Alalwan TA, Mahdi AM, Guido D, Tagliabue A · Nutrients · 2022-04-22

Observational human study

342. Factors associated with initiation of the modified Atkins diet in adults with drug-resistant epilepsy.

Quiroga-Padilla PJ, Briceño C, Mayor LC · Epilepsy & behavior : E&B · 2022-02-24

Preclinical / mechanistic

343. Ketogenic diet impairs neurological development of neonatal rats and affects biochemical composition of maternal brains: evidence of functional recovery in pups.

Kosiek W, Rauk Z, Szulc P, Cichy A, Rugieł M, Chwiej J, Janeczko K, Setkowicz Z · Brain structure & function · 2022-01-17

Observational human study

344. Efficacy and tolerability of the modified Atkins diet in children with drug-resistant genetic generalized epilepsy.

Kacker S, Nordli DR, Phitsanuwong C · Epileptic disorders : international epilepsy journal with videotape · 2021-11-27

Observational human study

345. The efficacy of non-fasting ketogenic diet protocol in the management of intractable epilepsy in pediatric patients: a single center study from Saudi Arabia.

Alameen Ali H, Muthaffar O, AlKarim N, Kayyali H, Elmardenly A, Tamim A, Alansari H · The Journal of international medical research · 2022-03-09

Observational human study

346. Outcomes of parenteral vs enteral ketogenic diet in pediatric super-refractory status epilepticus.

Chomtho S, Uaariyapanichkul J, Chomtho K · Seizure · 2022-02-05

Other

347. Effect of ketogenic diet for drug-resistant epilepsy on immunological cells.

Nassar MF, El-Gendy YGA, Hamza MT, Mohamed MN, Radwan N · Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2021-08-27

Case report / case series

348. Craniotomy Complicated by Severe Metabolic Acidosis Requiring Massive Transfusion in an Infant on Ketogenic Diet Therapy for Intractable Epilepsy.

Hayes SB, Munlemvo DM, Gillis HC, Tobias JD · International medical case reports journal · 2022-02-15

Case report / case series

349. Ketogenic Diet for a Young Adult Patient With Chronic-Phase Febrile Infection-Related Epilepsy Syndrome.

Obara K, Ono T · Cureus · 2022-02-10

Clinical trial / intervention

350. Probiotics counteract hepatic steatosis caused by ketogenic diet and upregulate AMPK signaling in a model of infantile epilepsy.

Mu C, Nikpoor N, Tompkins TA, Rho JM, Scantlebury MH, Shearer J · EBioMedicine · 2022-02-09

Systematic review / meta-analysis

351. Ketogenic diet in pediatric seizures: a randomized controlled trial review and meta-analysis.

Pizzo F, Collotta AD, Di Nora A, Costanza G, Ruggieri M, Falsaperla R · Expert review of neurotherapeutics · 2022-02-25

Review

352. Updates on the ketogenic diet therapy for pediatric epilepsy.

Ko A, Kwon HE, Kim HD · Biomedical journal · 2021-11-19

Clinical trial / intervention

353. Transcriptomic profile of epileptic children treated with ketogenic therapies.

Ruiz-Herrero J, Olaso-Gonzalez G, Serna E, Cañedo-Villarroya E, Correas AG, Gambini J, Gomez-Cabrera MC, Pedrón-Giner C, Vina J · Journal of integrative neuroscience · 2021-08-05

Other

354. Monitoring Glucose Concentrations in Children with Epilepsy on a Ketogenic Diet.

Schiller K, Avigdor T, Kortas A, Kunz M, Unterholzner G, Klingelhöfer M, Rauchenzauner M · Healthcare (Basel, Switzerland) · 2022-01-27

Other

355. Analysis of Factors That May Affect the Effectiveness of Ketogenic Diet Treatment in Pediatric and Adolescent Patients.

Winczewska-Wiktor A, Hirschfeld AS, Badura-Stronka M, Komasińska-Piotrowska P, Steinborn B · Journal of clinical medicine · 2022-01-25

Other

356. The Effect of the Ketogenic Diet on Adiponectin, Omentin and Vaspin in Children with Drug-Resistant Epilepsy.

Chyra M, Roczniak W, Świętochowska E, Dudzińska M, Oświęcimska J · Nutrients · 2022-01-22

Other

357. Efficacy of Anti-seizure Medications, Quinidine, and Ketogenic Diet Therapy for KCNT1-Related Epilepsy and Genotype-Efficacy Correlation Analysis.

Lin Z, Sang T, Yang Y, Wu Y, Dong Y, Ji T, Zhang Y, Wu Y, Gao K, Jiang Y · Frontiers in neurology · 2022-01-18

Review

358. Interactions between the gut microbiome and ketogenic diet in refractory epilepsy.

Özcan E, Lum GR, Hsiao EY · International review of neurobiology · 2022-06-25

Case report / case series

359. A rare case of hypomyelinating leukodystrophy-14 benefiting from ketogenic diet therapy.

Ünalp A, Köse M, Karaoğlu P, Güzin Y, Yılmaz Ü · The Turkish journal of pediatrics · 2022-09-09

Other

360. Evaluation of ketogenic diet therapy in children diagnosed with drug-resistant epilepsy: a single-center experience.

Yıldırım GK, Yağcı M, Uygur AÇ, Özen H, Yarar C, Çarman KB · The Turkish journal of pediatrics · 2022-07-28

Other

361. The effectiveness of the ketogenic diet in drug-resistant childhood epilepsy.

Yılmaz Ü, Edizer S, Akışin Z, Köse M, Güzin Y, Gürbüz G, Baysal BT, Sarıtaş S, Pekuz S, Kırkgöz HH, Yavuz M, Ünalp A · The Turkish journal of pediatrics · 2022-05-25

Other

362. Effects of dietary components on intestinal short-chain fatty acids (SCFAs) synthesis in healthy adult persons following a ketogenic diet.

Gudan A, Skonieczna-Żydecka K, Palma J, Drozd A, Stachowska E · Roczniki Panstwowego Zakladu Higieny · 2022-03-24

Randomized clinical trial

363. Prospective control study of efficacy and influencing factors of a ketogenic diet on refractory epilepsy in children.

Feng L, Wang J, Li X, Hu Y, Hong S, Jiang L · Translational pediatrics · 2021-11-26

Other

364. Medium-chain Triglyceride Ketogenic Diet as a Treatment Strategy for Adult Super-refractory Status Epilepticus.

Dutta K, Satishchandra P, Borkotokey M · Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2022-02-03

Observational human study

365. Efficacy of the Ketogenic Diet for Pediatric Epilepsy According to the Presence of Detectable Somatic mTOR Pathway Mutations in the Brain.

Ko A, Sim NS, Choi HS, Yang D, Kim SH, Lee JS, Kim DS, Lee JH, Kim HD, Kang HC · Journal of clinical neurology (Seoul, Korea) · 2020-12-21

Review

366. Novel UBE3A pathogenic variant in a large Georgian family produces non-convulsive status epilepticus responsive to ketogenic diet.

Melikishvili G, Bienvenu T, Tabatadze N, Gachechiladze T, Kurua E, Gverdtsiteli S, Melikishvili M, Dulac O · Seizure · 2021-11-24

Observational human study

367. Evaluation of the seizure control and the tolerability of ketogenic diet in Chinese children with structural drug-resistant epilepsy.

Dou X, Xu X, Mo T, Chen H, Wang Z, Li X, Jia S, Wang D · Seizure · 2021-11-25

Other

368. Modified Atkins diet for drug-resistant epilepsy and the risk of urolithiasis.

Nassar MF, El-Rashidy OF, Abdelhamed MH, Shata MO · Pediatric research · 2021-09-08

Systematic review / meta-analysis

369. The Role of the Gut Microbiota on the Beneficial Effects of Ketogenic Diets.

Attaye I, van Oppenraaij S, Warmbrunn MV, Nieuwdorp M · Nutrients · 2021-12-31

Observational human study

370. [Treatment of refractory epilepsy. A comparison between classic ketogenic diet and modified Atkins diet in terms of efficacy, adherence, and undesirable effects].

Cabrera AM, Fain H, Fain B, Muniategui J, Buiras VM, Galicchio S, Cacchia PA, Retamero M, Ocampo RP, Porto MB · Nutricion hospitalaria · 2021-08-27

Randomized clinical trial

371. Nutritional Formulation for Patients with Angelman Syndrome: A Randomized, Double-Blind, Placebo-Controlled Study of Exogenous Ketones.

Carson RP, Herber DL, Pan Z, Phibbs F, Key AP, Gouelle A, Ergish P, Armour EA, Patel S, Duis J · The Journal of nutrition · 2021-04-08

Observational human study

372. Long-term effectiveness and adverse effects of ketogenic diet therapy in infants with drug-resistant epilepsy treated at a single center in Argentina.

Armeno M, Verini A, Caballero E, Cresta A, Valenzuela GR, Caraballo R · Epilepsy research · 2021-10-30

Clinical trial / intervention

373. Qualitative exploration of feasibility and acceptability of the modified Atkins diet therapy for children with drug resistant epilepsy in Kenya.

Samia P, Naanyu V, Cross JH, Idro R, Boon P, Wilmshurst J, Luchters S · Epilepsy & behavior : E&B · 2021-11-02

Review

374. Microbiota-gut-brain axis: A novel potential target of ketogenic diet for epilepsy.

Tang Y, Wang Q, Liu J · Current opinion in pharmacology · 2021-10-01

Other

375. The effect of ketogenic diet on thyroid functions in children with drug-resistant epilepsy.

Yılmaz Ü, Nalbantoğlu Ö, Güzin Y, Edizer S, Akışin Z, Pekuz S, Kırkgöz HH, Yavuz M, Ünalp A, Özkan B · Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2021-04-12

Observational human study

376. The effect of the ketogenic diet on leptin, chemerin and resistin levels in children with epilepsy.

Chyra M, Swietochowska E, Gorska-Flak K, Dudzinska M, Oswiecimska J · Neuro endocrinology letters · 2021-02-10

Preclinical / mechanistic

377. Adenosine Receptors Modulate the Exogenous Ketogenic Supplement-Evoked Alleviating Effect on Lipopolysaccharide-Generated Increase in Absence Epileptic Activity in WAG/Rij Rats.

Brunner B, Ari C, D'Agostino DP, Kovács Z · Nutrients · 2021-11-15

Observational human study

378. Evaluation of the effects of ketogenic diet therapy on sleep quality in children with drug-resistant epilepsy and their mothers.

Ünalp A, Baysal BT, Sarıtaş S, Güzin Y, Edizer S, Akışın Z, Yılmaz Ü · Epilepsy & behavior : E&B · 2021-10-07

Observational human study

379. Altered cytokine levels in cerebrospinal fluid following ketogenic diet of children with refractory epilepsy.

Wickström R, Ygberg S, Lindefeldt M, Dahlin M · Epilepsy research · 2021-09-22

Observational human study

380. Efficacy and safety of ketogenic dietary theraphies in infancy. A single-center experience in 42 infants less than two years of age.

Ruiz-Herrero J, Cañedo-Villarroya E, Pérez-Sebastián I, Bernardino-Cuesta B, Pedrón-Giner C · Seizure · 2021-08-29

Clinical trial / intervention

381. The relation of etiology based on the 2017 ILAE classification to the effectiveness of the ketogenic diet in drug-resistant epilepsy in childhood.

Breu M, Häfele C, Trimmel-Schwahofer P, Schmidt WM, Laconne F, Vodopiutz J, Male C, Dressler A · Epilepsia · 2021-08-28

Systematic review / meta-analysis

382. Considering safety and patient tolerance in the use of ketogenic diet in the management of refractory and super-refractory status epilepticus: a systematic review.

Dozières-Puyravel B, Höhn S, Auvin S · Expert review of neurotherapeutics · 2021-07-24

Other

383. Ketogenic diet as elective treatment in patients with drug-unresponsive hyperinsulinemic hypoglycemia caused by glucokinase mutations.

Maiorana A, Caviglia S, Greco B, Alfieri P, Cumbo F, Campana C, Bernabei SM, Cusmai R, Mosca A, Dionisi-Vici C · Orphanet journal of rare diseases · 2021-10-11

Other

384. New developments for dietary treatment of epilepsy after a century of history for the ketogenic diet.

Auvin S · Brain communications · 2021-10-07

Case report / case series

385. Super-refractory status epilepticus and ketogenic diet in intensive care: a series report.

Camões J, Reis AH, Sousa L, Gomes E · Revista Brasileira de terapia intensiva · 2022-01-24

Review

386. Practical Considerations for Ketogenic Diet in Adults With Super-Refractory Status Epilepticus.

Kaul N, Laing J, Nicolo JP, Nation J, Kwan P, O'Brien TJ · Neurology. Clinical practice · 2020-05-31

Other

387. International Recommendations for the Management of Adults Treated With Ketogenic Diet Therapies.

Cervenka MC, Wood S, Bagary M, Balabanov A, Bercovici E, Brown MG, Devinsky O, Di Lorenzo C, Doherty CP, Felton E, Healy LA, Klein P, Kverneland M, Lambrechts D, Langer J, Nathan J, Munn J, Nguyen P, Phillips M, Roehl K, Tanner A, Williams C, Zupec-Kania B · Neurology. Clinical practice · 2019-11-14

Case report / case series

388. Beneficial effects of the ketogenic diet on drug-resistant epileptic encephalopathy associated with a de novo NBEA pathogenic variant.

Schiavoni S, Spagnoli C, Rizzi S, Salerno GG, Frattini D, Pisani F, Fusco C · Epileptic disorders : international epilepsy journal with videotape · 2021-10-06

Other

389. Is the antiseizure effect of ketogenic diet in children with drug-resistant epilepsy mediated through proinflammatory cytokines?

Thambi M, Nathan J, Bailur S, Unnikrishnan MK, Ballal M, Radhakrishnan K · Epilepsy research · 2021-07-21

Observational human study

390. Ketogenic Diet Therapy for Epilepsy Associated With Aicardi Syndrome.

Sanchez MAR, Cervenka MC, Bessone SK, Kossoff EH · Journal of child neurology · 2021-07-09

Other

391. The effect of ketogenic diet on serum lipid concentrations in children with medication resistant epilepsy.

Yılmaz Ü, Edizer S, Köse M, Akışin Z, Güzin Y, Pekuz S, Kırkgöz HH, Yavuz M, Ünalp A · Seizure · 2021-06-10

Observational human study

392. Efficacy and tolerability of a whey-based, medium-chain triglyceride-enhanced ketogenic formula in children with refractory epilepsy: A retrospective study.

Wheeler CE, Temkit M, Wilfong AA, Vanatta L, Jarrar R · Seizure · 2021-05-08

Preclinical / mechanistic

393. A ketogenic diet protects DBA/1 and Scn1aR1407X/+ mice against seizure-induced respiratory arrest independent of ketosis.

Crotts MS, Kim Y, Bravo E, Richerson GB, Teran FA · Epilepsy & behavior : E&B · 2021-09-29

Other

394. Expanding Dietary Therapy Beyond the Classic Ketogenic Diet: On the Use of the Modified Atkins Diet and Low Glycemic Index Treatment in Pediatric Epilepsy.

Whitney R, Nair RR · Indian pediatrics · 2021-09-11

Randomized clinical trial

395. Modified Atkins Diet vs Low Glycemic Index Treatment for Drug-Resistant Epilepsy in Children: An Open Label, Randomized Controlled Trial.

Gupta S, Dabla S, Kaushik JS · Indian pediatrics · 2021-02-25

Case report / case series

396. Ketogenic diet (KD) therapy in the acute phase of febrile infection-related epilepsy syndrome (FIRES): a case report.

Li WJ, Xue CL, Zhang Y, Wu LH, Chen DM, Chen F, Xu J, Li Z, Miao HJ · Translational pediatrics · 2021-03-25

Other

397. Challenges faced by people with epilepsy on ketogenic diet therapy and their caregivers during the COVID-19 pandemic in Brazil.

Alencastro Veiga Domingues Carneiro R, Dos Santos Lunardi M, Matheus Uberna Giacomini F, Kurrle Rieger D, Dubois Moreira J, Carina Ribeiro da Silva L, Pereira Brito Sampaio L, Lin K · Epilepsy & behavior : E&B · 2021-07-10

Preclinical / mechanistic

398. The link between brain acidosis, breathing and seizures: a novel mechanism of action for the ketogenic diet in a model of infantile spasms.

Choudhary A, Mu C, Barrett KT, Charkhand B, Williams-Dyjur C, Marks WN, Shearer J, Rho JM, Scantlebury MH · Brain communications · 2021-08-28

Other

399. Hypoglycemia during treatment with the ketogenic diet in a child with refractory epilepsy-results of continuous glucose monitoring.

Brožová K, Holubová A, Bořilová P, Brabec M, Kohout P, Hadač J, Brož J · Neuro endocrinology letters · 2020-09-06

Review

400. Ketone Bodies in the Brain Beyond Fuel Metabolism: From Excitability to Gene Expression and Cell Signaling.

García-Rodríguez D, Giménez-Cassina A · Frontiers in molecular neuroscience · 2021-08-27

Preclinical / mechanistic

401. Ketogenic diet-mediated seizure reduction preserves CA1 cell numbers in epileptic Kcna1-null mice: An unbiased stereological assessment.

Simeone KA, Wilke JC, Matthews SA, Simeone TA, Rho JM · Epilepsia · 2021-07-07

Observational human study

402. Does the size of a ketogenic diet admission group influence outcomes?

Alem D, Jager L, Turner Z, Stanfield A, Kossoff EH · Epilepsy & behavior : E&B · 2021-05-28

Preclinical / mechanistic

403. Neuroprotective effect of both synbiotics and ketogenic diet in a pentylenetetrazol-induced acute seizure murine model.

Eor JY, Son YJ, Kim JY, Kang HC, Youn SE, Kim JH, Kim SH · Epilepsy research · 2021-05-13

Systematic review / meta-analysis

404. Efficacy and safety of corpus callosotomy and ketogenic diet in children with Lennox Gastaut syndrome: a systematic review and meta-analysis.

Sharawat IK, Panda PK, Sihag RK, Panda P, Dawman L · Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2021-04-19

Other

405. Keto-on-the-Clock: A Survey of Dietetic Care Contact Time Taken to Provide Ketogenic Diets for Drug-Resistant Epilepsy in the UK.

Lambert B, Lightfoot K, Meskell R, Whiteley VJ, Martin-McGill KJ, Schoeler NE · Nutrients · 2021-07-21

Review

406. A Clinical Perspective of Low Carbohydrate Ketogenic Diets: A Narrative Review.

Sukkar SG, Muscaritoli M · Frontiers in nutrition · 2021-07-12

Review

407. Ketogenic diet, seizure control, and cardiometabolic risk in adult patients with pharmacoresistant epilepsy: a review.

Neves GS, Lunardi MS, Lin K, Rieger DK, Ribeiro LC, Moreira JD · Nutrition reviews · 2020-11-25

Systematic review / meta-analysis

408. Ketogenic diet for mitochondrial disease: a systematic review on efficacy and safety.

Zweers H, van Wegberg AMJ, Janssen MCH, Wortmann SB · Orphanet journal of rare diseases · 2021-07-03

Clinical trial / intervention

409. Emerging Role of the Ketogenic Dietary Therapies beyond Epilepsy in Child Neurology.

Kapoor D, Garg D, Sharma S · Annals of Indian Academy of Neurology · 2021-05-11

Case report / case series

410. Cerebral folate deficiency in two siblings caused by biallelic variants including a novel mutation of FOLR1 gene: Intrafamilial heterogeneity following early treatment and the role of ketogenic diet.

Papadopoulou MT, Dalpa E, Portokalas M, Katsanika I, Tirothoulaki K, Spilioti M, Gerou S, Plecko B, Evangeliou AE · JIMD reports · 2021-06-04

Randomized clinical trial

411. Evaluation of the Modified Atkins Diet for the Treatment of Epileptic Spasms Refractory to Hormonal Therapy: A Randomized Controlled Trial.

Sharma S, Goel S, Kapoor D, Garg D, Panda I, Elwadhi A, Patra B, Mukherjee SB, Pemde H · Journal of child neurology · 2021-04-09

Preclinical / mechanistic

412. The ketogenic diet raises brain oxygen levels, attenuates postictal hypoxia, and protects against learning impairments.

Gom RC, Bhatt D, Villa BR, George AG, Lohman AW, Mychasiuk R, Rho JM, Teskey GC · Neurobiology of disease · 2021-03-17

Clinical trial / intervention

413. The Feasibility and Tolerability of Medium Chain Triglycerides in Women with a Catamenial Seizure Pattern on the Modified Atkins Diet.

Felton EA, Henry-Barron BJ, Jan AK, Shegelman A, Faltersack K, Vizthum D, Cervenka MC · Nutrients · 2021-06-30

Clinical trial / intervention

414. Graph Theory-Based Electroencephalographic Connectivity and Its Association with Ketogenic Diet Effectiveness in Epileptic Children.

Su TY, Hung PL, Chen C, Lin YJ, Peng SJ · Nutrients · 2021-06-25

Observational human study

415. Ketogenic Diet Therapy for the Treatment of Post-encephalitic and Autoimmune-Associated Epilepsies.

Husari KS, Cervenka MC · Frontiers in neurology · 2021-06-16

Observational human study

416. Ketogenic Diet in the Treatment of Super-Refractory Status Epilepticus at a Pediatric Intensive Care Unit: A Single-Center Experience.

Breu M, Häfele C, Glatter S, Trimmel-Schwahofer P, Golej J, Male C, Feucht M, Dressler A · Frontiers in neurology · 2021-06-03

Review

417. Growth and nutritional status of pediatric patients treated with the ketogenic diet.

Santiworakul C, Chomtho K, Chomtho S · Asia Pacific journal of clinical nutrition · 2021-06-30

Observational human study

418. Gut flora and metabolism are altered in epilepsy and partially restored after ketogenic diets.

Gong X, Cai Q, Liu X, An D, Zhou D, Luo R, Peng R, Hong Z · Microbial pathogenesis · 2021-04-21

Other

419. The Role of Mentorship and Collaboration in the Fall and Rebirth of the Ketogenic Diet.

Catenaccio E, Bergin AM, Pinto ALR, Nickels K, Kossoff EH · Pediatric neurology · 2021-03-04

Other

420. Micronutrient supplementation needs more attention in patients with refractory epilepsy under ketogenic diet treatment.

Prudencio MB, de Lima PA, Murakami DK, Sampaio LPB, Damasceno NRT · Nutrition (Burbank, Los Angeles County, Calif.) · 2021-01-29

Other

421. Successful implementation of classical ketogenic dietary therapy in a patient with Niemann-Pick disease type C.

Höller A, Albrecht U, Baumgartner Sigl S, Zöggeler T, Ramoser G, Bernar B, Karall D, Scholl-Bürgi S · Molecular genetics and metabolism reports · 2021-02-05

Observational human study

422. Neutropenia in Children Treated With Ketogenic Diet Therapy.

Munro K, Keller AE, Lowe H, Ferrara E, Whitney R, Liu CYM, Zak M, Chan V, Kobayashi J, Donner EJ · Journal of child neurology · 2021-01-04

Observational human study

423. Ketogenic diet experience at Ondokuz Mayıs University.

Tekin E, Serdaroğlu FM, Şahin Ş, Taşdemir HA · Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2020-10-26

Clinical trial / intervention

424. The ketogenic diet increases Neuregulin 1 expression via elevating histone acetylation and its anti-seizure effect requires ErbB4 kinase activity.

Wang J, Huang J, Yao S, Wu JH, Li HB, Gao F, Wang Y, Huang GB, You QL, Li J, Chen X, Sun XD · Cell & bioscience · 2021-05-21

Review

425. The Chemistry of the Ketogenic Diet: Updates and Opportunities in Organic Synthesis.

Williams MS, Turos E · International journal of molecular sciences · 2021-05-15

Observational human study

426. Adjunctive use of the ketogenic diet in a young adult with UBE2A deficiency syndrome and super-refractory status epilepticus.

Allen CM, Hall CA, Cox NE, Ryan H, De Beer T, O'Donoghue MF · Epilepsy & behavior reports · 2021-05-07

Other

427. Ketogenic Diets for Drug-Resistant Epilepsy.

Covey C · American family physician · 2021-04-30

Other

428. Evaluation of E-Health Applications for Paediatric Patients with Refractory Epilepsy and Maintained on Ketogenic Diet.

Costa AM, Marchiò M, Bruni G, Bernabei SM, Cavalieri S, Bondi M, Biagini G · Nutrients · 2021-04-09

Case report / case series

429. Ketogenic Diet in Infants with Early-Onset Epileptic Encephalopathy and SCN2A Mutation.

Tian X, Zhang Y, Zhang J, Lu Y, Men X, Wang X · Yonsei medical journal · 2020-08-12

Observational human study

430. The psychiatric effects of ketogenic diet therapy on adults with chronic epilepsy.

Shegelman A, Carson KA, McDonald TJW, Henry-Barron BJ, Diaz-Arias LA, Cervenka MC · Epilepsy & behavior : E&B · 2021-02-18

Other

431. Efficacy of 3 Major Ketogenic Diet Therapies in Children With Drug-Resistant Epilepsy.

Yue J, Liu SY, Yang H · JAMA pediatrics · 2021-01-26

Other

432. Efficacy of 3 Major Ketogenic Diet Therapies in Children With Drug-Resistant Epilepsy-Reply.

Sondhi V, Gulati S · JAMA pediatrics · 2021-01-26

Case report / case series

433. Possible Role of High-Dose Barbiturates and Early Administration of Parenteral Ketogenic Diet for Reducing Development of Chronic Epilepsy in Febrile Infection-Related Epilepsy Syndrome: A Case Report.

Baba S, Okanishi T, Ohsugi K, Suzumura R, Niimi K, Shimizu S, Sakihama H, Itamura S, Hirano K, Nishimura M, Fujimoto A, Enoki H · Neuropediatrics · 2020-11-23

Clinical trial / intervention

434. The efficacy comparison of classic ketogenic diet and modified Atkins diet in children with refractory epilepsy: a clinical trial.

Poorshiri B, Barzegar M, Tahmasebi S, Shiva S, Raeisi S, Ebadi Z · Acta neurologica Belgica · 2019-11-01

Review

435. Ketogenic diet: overview, types, and possible anti-seizure mechanisms.

Barzegar M, Afghan M, Tarmahi V, Behtari M, Rahimi Khamaneh S, Raeisi S · Nutritional neuroscience · 2019-06-26

Preclinical / mechanistic

436. One Month of Classic Therapeutic Ketogenic Diet Decreases Short Chain Fatty Acids Production in Epileptic Patients.

Ferraris C, Meroni E, Casiraghi MC, Tagliabue A, De Giorgis V, Erba D · Frontiers in nutrition · 2021-03-29

Preclinical / mechanistic

437. Leucine-Enriched Essential Amino Acids Enhance the Antiseizure Effects of the Ketogenic Diet in Rats.

Takeuchi F, Nishikata N, Nishimura M, Nagao K, Kawamura M · Frontiers in neuroscience · 2021-03-19

Observational human study

438. Combined use of the ketogenic diet and vagus nerve stimulation in pediatric drug-resistant epilepsy.

Abdelmoity AT, Le Pichon JB, Abdelmoity SA, Sherman AK, Hall AS, Abdelmoity AT · Epilepsia open · 2021-01-15

Other

439. Differential ketogenic diet-induced shift in CSF lipid/carbohydrate metabolome of pediatric epilepsy patients with optimal vs. no anticonvulsant response: a pilot study.

Masino SA, Ruskin DN, Freedgood NR, Lindefeldt M, Dahlin M · Nutrition & metabolism · 2021-03-01

Other

440. Drug-drug and drug-food interactions in an infant with early-onset SCN2A epilepsy treated with carbamazepine, phenytoin and a ketogenic diet.

Welzel T, Ziesenitz VC, Weber P, Datta AN, van den Anker JN, Gotta V · British journal of clinical pharmacology · 2020-08-13

Review

441. Pearls and Pitfalls of Introducing Ketogenic Diet in Adult Status Epilepticus: A Practical Guide for the Intensivist.

Katz JB, Owusu K, Nussbaum I, Beekman R, DeFilippo NA, Gilmore EJ, Hirsch LJ, Cervenka MC, Maciel CB · Journal of clinical medicine · 2021-02-22

Clinical trial / intervention

442. Neuregulin 1/ErbB4 signaling contributes to the anti-epileptic effects of the ketogenic diet.

Wang J, Huang J, Li YQ, Yao S, Wu CH, Wang Y, Gao F, Xu MD, Huang GB, Zhao CQ, Wu JH, Zhang YL, Jiao R, Deng ZH, Jie W, Li HB, Xuan A, Sun XD · Cell & bioscience · 2021-02-03

Case report / case series

443. Ketogenic Diet Therapy for Intractable Epilepsy in Infantile Alexander Disease: A Small Case Series and Analyses of Astroglial Chemokines and Proinflammatory Cytokines.

Hamada S, Kato T, Kora K, Kawaguchi T, Okubo T, Ide M, Tanaka T, Yoshida T, Sakakibara T · Epilepsy research · 2020-12-03

Clinical trial / intervention

444. Reducing Prescribing Errors in Hospitalized Children on the Ketogenic Diet.

Siegel BI, Johnson M, Dawson TE, Kurzen E, Holt PJ, Wolf DS, Orenstein EW · Pediatric neurology · 2020-11-22

Case report / case series

445. Hypercalcemia in Children Using the Ketogenic Diet: A Multicenter Study.

Hawkes CP, Roy SM, Dekelbab B, Frazier B, Grover M, Haidet J, Listman J, Madsen S, Roan M, Rodd C, Sopher A, Tebben P, Levine MA · The Journal of clinical endocrinology and metabolism · 2020-08-23

Clinical trial / intervention

446. Energy Metabolism and Ketogenic Diets: What about the Skeletal Health? A Narrative Review and a Prospective Vision for Planning Clinical Trials on this Issue.

Merlotti D, Cosso R, Eller-Vainicher C, Vescini F, Chiodini I, Gennari L, Falchetti A · International journal of molecular sciences · 2021-01-04

Other

447. Ketogenic diet therapy map of Turkey.

Serdaroğlu A, Arhan EP, Ketogenic Diet Therapy Map of Turkey Study Group · The Turkish journal of pediatrics · 2021-11-05

Case report / case series

448. Ketogenic Diet for Super-refractory Status Epilepticus: A Case Series and Review of Literature.

Anand S, Vibhute AS, Das A, Pandey S, Paliwal VK · Annals of Indian Academy of Neurology · 2021-02-05

Other

449. Ketogenic diet and growth in Chinese infants with refractory epilepsy.

Liu Y, Wan J, Gao Z, Xu L, Kong L · Asia Pacific journal of clinical nutrition · 2021-03-31

Observational human study

450. The role of ketogenic diet in controlling epileptic seizures.

Al-Baradie RS, Alshammari A, Alajmi M, Bashir S · Neurosciences (Riyadh, Saudi Arabia) · 2020-06-21

Case report / case series

451. Ketogenic diet in a patient with refractory status epilepticus due to POLG mutation.

Koessler M, Haberlandt E, Karall D, Baumann M, Höller A, Scholl-Bürgi S · JIMD reports · 2020-10-01

Preclinical / mechanistic

452. Gut microbiota modulation by both Lactobacillus fermentum MSK 408 and ketogenic diet in a murine model of pentylenetetrazole-induced acute seizure.

Eor JY, Tan PL, Son YJ, Kwak MJ, Kim SH · Epilepsy research · 2020-11-21

Systematic review / meta-analysis

453. Use of ketogenic diets in the treatment of central nervous system diseases: a systematic review.

Christensen MG, Damsgaard J, Fink-Jensen A · Nordic journal of psychiatry · 2020-08-06

Review

454. Metabolic epilepsies amenable to ketogenic therapies: Indications, contraindications, and underlying mechanisms.

Gavrilovici C, Rho JM · Journal of inherited metabolic disease · 2020-08-11

Clinical trial / intervention

455. Ketogenic Diet for the Treatment and Prevention of Dementia: A Review.

Davis JJ, Fournakis N, Ellison J · Journal of geriatric psychiatry and neurology · 2020-01-30

Observational human study

456. An Examination of Serum Acylcarnitine and Amino Acid Profiles at Different Time Point of Ketogenic Diet Therapy and Their Association of Ketogenic Diet Effectiveness.

Hung PL, Lin JL, Chen C, Hung KY, Hsieh TY, Hsu MH, Kuo HC, Lin YJ · Nutrients · 2020-12-23

Preclinical / mechanistic

457. The Effects of a Ketogenic Medium-Chain Triglyceride Diet on the Feces in Dogs With Idiopathic Epilepsy.

Pilla R, Law TH, Pan Y, Zanghi BM, Li Q, Want EJ, Lidbury JA, Steiner JM, Suchodolski JS, Volk HA · Frontiers in veterinary science · 2020-12-22

Review

458. [Ketogenic diet – mechanism of action and perspectives for the use in the therapy: data from clinical studies].

Pondel N, Liśkiewicz D, Liśkiewicz A · Postepy biochemii · 2020-12-13

Other

459. The Ketogenic Diet Increases In Vivo Glutathione Levels in Patients with Epilepsy.

Napolitano A, Longo D, Lucignani M, Pasquini L, Rossi-Espagnet MC, Lucignani G, Maiorana A, Elia D, De Liso P, Dionisi-Vici C, Cusmai R · Metabolites · 2020-12-10

Other

460. Reply: Rational therapy with vigabatrin and a ketogenic diet in a patient with GAD1 deficiency.

Weckhuysen S, Tajsharghi H · Brain : a journal of neurology · 2020-11-11

Other

461. Rational therapy with vigabatrin and a ketogenic diet in a patient with GAD1 deficiency.

von Hardenberg S, Richter MF, Hethey S, Yaspo ML, Auber B, Schlegelberger B, Illig T, Guthmann F, Christen HJ, Ripperger T, Bergmann AK · Brain : a journal of neurology · 2020-11-05

Clinical trial / intervention

462. Incidence of potential adverse events during hospital-based ketogenic diet initiation among children with drug-resistant epilepsy.

Mir A, Albaradie R, Alamri A, AlQahtani M, Hany E, Hussain A, Joseph M, Bashir S · Epilepsia open · 2020-11-25

Other

463. Challenges in telemedicine for adult patients with drug-resistant epilepsy undergoing ketogenic diet treatment during the COVID-19 pandemic in the public healthcare system in Brazil.

Lima MC, Sander M, Dos Santos Lunardi M, Ribeiro LC, Rieger DK, Lin K, Moreira JD · Epilepsy & behavior : E&B · 2020-11-21

Review

464. Anticonvulsant mechanisms of the ketogenic diet and caloric restriction.

Rudy L, Carmen R, Daniel R, Artemio R, Moisés RO · Epilepsy research · 2020-11-01

Clinical trial / intervention

465. Ketogenic Diet Therapies for Seizures and Status Epilepticus.

McDonald TJW, Cervenka MC · Seminars in neurology · 2020-11-05

Randomized clinical trial

466. Can change in gut microbiota composition be used as a surrogate marker of treatment efficacy of ketogenic diet in patients with drug-resistant epilepsy?

Thambi M, Nathan J, Radhakrishnan K · Epilepsy & behavior : E&B · 2020-10-20

Review

467. Perioperative Management of Children on Ketogenic Dietary Therapies.

Conover ZR, Talai A, Klockau KS, Ing RJ, Chatterjee D · Anesthesia and analgesia · 2020-08-10

Case report / case series

468. Use of Perampanel and a Ketogenic Diet in Nonketotic Hyperglycinemia: A Case Report.

Daida A, Hamano SI, Ikemoto S, Hirata Y, Matsuura R, Koichihara R, Oba D, Ohashi H · Neuropediatrics · 2020-03-16

Review

469. The Ketogenic Diet for the Treatment of Mood Disorders in Comorbidity With Epilepsy in Children and Adolescents.

Operto FF, Matricardi S, Pastorino GMG, Verrotti A, Coppola G · Frontiers in pharmacology · 2020-11-24

Review

470. Caloric Restriction and Ketogenic Diet Therapy for Epilepsy: A Molecular Approach Involving Wnt Pathway and KATP Channels.

Rubio C, Luna R, Rosiles A, Rubio-Osornio M · Frontiers in neurology · 2020-11-05

Observational human study

471. [Clinical characteristics and ketogenic diet therapy of glucose transporter type 1 deficiency syndrome in children: a multicenter clinical study].

Yu LF, Zhang YQ, Duan J, Ni Y, Gong XY, Lu ZY, Liao JX, Lu XP, Shi ZN, Lei MF, Zhong JM, Zha J, Zhou SZ · Zhonghua er ke za zhi = Chinese journal of pediatrics · 2020-10-29

Other

472. Telemedicine, drug-resistant epilepsy, and ketogenic dietary therapies: A patient survey of a pediatric remote-care program during the COVID-19 pandemic.

Semprino M, Fasulo L, Fortini S, Martorell Molina CI, González L, Ramos PA, Martínez C, Caraballo R · Epilepsy & behavior : E&B · 2020-10-03

Randomized clinical trial

473. Ketogenic diet for infants with epilepsy: A literature review.

Falsaperla R, D'Angelo G, Praticò AD, Mauceri L, Barbagallo M, Pavone P, Catanzaro S, Gitto E, Corsello G, Ruggieri M · Epilepsy & behavior : E&B · 2020-09-28

Review

474. A unifying mechanism of ketogenic diet action: The multiple roles of nicotinamide adenine dinucleotide.

Elamin M, Ruskin DN, Sacchetti P, Masino SA · Epilepsy research · 2020-09-14

Review

475. Ketogenic diet and Neuroinflammation.

Koh S, Dupuis N, Auvin S · Epilepsy research · 2020-09-06

Review

476. Ketogenic diet, neuroprotection, and antiepileptogenesis.

Murugan M, Boison D · Epilepsy research · 2020-08-19

Observational human study

477. Longitudinal changes in insulin resistance in children with epilepsy on ketogenic diet: Prevalence and risk factors.

Kong J, Nam SO, Ko A, Byun SY, Lim TJ, Kim YM, Yeon GM, Cho JW, Lee YJ · Epilepsy & behavior : E&B · 2020-08-22

Other

478. Pediatric to Adult Transitions of Ketogenic Dietary Therapy for Epilepsy.

Seaborg K, Wang X, Olson C, Felton EA · Journal of child neurology · 2020-07-23

Review

479. Ketogenic Diet in patients with refractory epilepsy.

Rebollo G MJ, Díaz Sm X, Soto R M, Pacheco A J, Witting E S, Daroch R I, Moraga M F · Revista chilena de pediatria · 2019-12-16

Other

480. [Ketogenic diet for refractory childhood epilepsy].

Castro V F, Heresi V C · Revista chilena de pediatria · 2021-01-05

Other

481. Ketogenic diet in drug-resistant epilepsy with encephalopathy.

Mc Manus EJ, Mc Coy S, Lynch CDP, C L Phillips M · Internal medicine journal · 2019-11-11

Review

482. What are the effects of ketogenic diets on drug-resistant epilepsy? A Cochrane Review summary with commentary.

Arman S · Developmental medicine and child neurology · 2020-08-18

Randomized clinical trial

483. Efficacy of Ketogenic Diet, Modified Atkins Diet, and Low Glycemic Index Therapy Diet Among Children With Drug-Resistant Epilepsy: A Randomized Clinical Trial.

Sondhi V, Agarwala A, Pandey RM, Chakrabarty B, Jauhari P, Lodha R, Toteja GS, Sharma S, Paul VK, Kossoff E, Gulati S · JAMA pediatrics · 2020-08-08

Systematic review / meta-analysis

484. Efficacy of the ketogenic diet in patients with Dravet syndrome: A meta-analysis.

Wang YQ, Fang ZX, Zhang YW, Xie LL, Jiang L · Seizure · 2020-07-18

Other

485. Effects of modified Atkins diet on thyroid function in adult patients with pharmacoresistant epilepsy.

Molteberg E, Thorsby PM, Kverneland M, Iversen PO, Selmer KK, Nakken KO, Taubøll E · Epilepsy & behavior : E&B · 2020-07-19

Review

486. A gut feeling about the ketogenic diet in epilepsy.

Pittman QJ · Epilepsy research · 2020-06-29

Preclinical / mechanistic

487. Proteomics for Studying the Effects of Ketogenic Diet Against Lithium Chloride/Pilocarpine Induced Epilepsy in Rats.

Zheng YQ, Jin MF, Suo GH, Wu YJ, Sun YX, Ni H · Frontiers in neuroscience · 2020-09-29

Other

488. Families' Perception of Classic Ketogenic Diet Management in Acute Medical Conditions: A Web-Based Survey.

Pasca L, Varesio C, Ferraris C, Guglielmetti M, Trentani C, Tagliabue A, Veggiotti P, De Giorgis V · Nutrients · 2020-09-24

Review

489. Adenosine and Ketogenic Treatments.

Ruskin DN, Kawamura M, Masino SA · Journal of caffeine and adenosine research · 2020-09-16

Preclinical / mechanistic

490. MRI spectroscopic and tractography studies indicate consequences of long-term ketogenic diet.

Gzieło K, Janeczko K, Węglarz W, Jasiński K, Kłodowski K, Setkowicz Z · Brain structure & function · 2020-07-17

Review

491. Mental, emotional, and behavioral effects of ketogenic diet for non-epileptic neuropsychiatric conditions.

Grigolon RB, Gerchman F, Schöffel AC, Hawken ER, Gill H, Vazquez GH, Mansur RB, McIntyre RS, Brietzke E · Progress in neuro-psychopharmacology & biological psychiatry · 2020-04-17

Review

492. Therapeutic Use of the Ketogenic Diet in Refractory Epilepsy: What We Know and What Still Needs to Be Learned.

Zarnowska IM · Nutrients · 2020-08-27

Review

493. Exploring the mechanisms of action of the antidepressant effect of the ketogenic diet.

Ricci A, Idzikowski MA, Soares CN, Brietzke E · Reviews in the neurosciences · 2019-08-08

Observational human study

494. The efficacy and safety of a ketogenic diet for children with refractory epilepsy in China: a retrospective single-center cohort study.

Li H, Ouyang M, Zhang P, Fei L, Hu X · Translational pediatrics · 2020-09-21

Observational human study

495. Ketogenic diet treatment of children in the intensive care unit: Safety, tolerability, and effectiveness.

Worden LT, Abend NS, Bergqvist AGC · Seizure · 2020-07-13

Other

496. Effects of the ketogenic diet on platelet counts and global coagulation tests in childhood epilepsy.

Dressler A, Chiara H, Benninger F, Waldhoer T, Gröppel G, Trimmel-Schwahofer P, Samueli S, Reithofer E, Elisa E, Feucht M, Male C · Seizure · 2020-05-04

Review

497. The ketogenic diet for infants: How long can you go?

Dressler A, Trimmel-Schwahofer P · Epilepsy research · 2020-05-06

Other

498. Long-term outcomes of ketogenic diet in patients with tuberous sclerosis complex-derived epilepsy.

Youn SE, Park S, Kim SH, Lee JS, Kim HD, Kang HC · Epilepsy research · 2020-04-29

Case report / case series

499. Successful treatment of intractable epilepsy with ketogenic diet therapy in twins with ALG3-CDG.

Paketci C, Edem P, Hiz S, Sonmezler E, Soydemir D, Sarikaya Uzan G, Oktay Y, O'Heir E, Beltran S, Laurie S, Töpf A, Lochmuller H, Horvath R, Yis U · Brain & development · 2020-05-07

Preclinical / mechanistic

500. Gestational exposure to a ketogenic diet increases sociability in CD-1 mice.

Arqoub AMS, Flynn KG, Martinez LA · Behavioral neuroscience · 2020-03-30

Preclinical / mechanistic

501. Ketogenic Diet Provided During Three Months Increases KCC2 Expression but Not NKCC1 in the Rat Dentate Gyrus.

Granados-Rojas L, Jerónimo-Cruz K, Juárez-Zepeda TE, Tapia-Rodríguez M, Tovar AR, Rodríguez-Jurado R, Carmona-Aparicio L, Cárdenas-Rodríguez N, Coballase-Urrutia E, Ruíz-García M, Durán P · Frontiers in neuroscience · 2020-07-07

Other

502. Ketogenic diet in Zambia: Managing drug-resistant epilepsy in a low and middle income country.

Nkole KL, Kawatu N, Patel AA, Kanyinji C, Njobvu T, Chipeta J, Musuku J, Ciccone O, Tarrant S, Bergin AM · Epilepsy & behavior reports · 2020-07-03

Observational human study

503. Use of Remote Monitoring by E-mail for Long-Term Management of the Classic Ketogenic Diet.

Ferraris C, Guglielmetti M, Tamagni E, Trentani C, De Giorgis V, Pasca L, Varesio C, Ferraro OE, Tagliabue A · Nutrients · 2020-06-19

Randomized clinical trial

504. Efficacy and Safety of a Ketogenic Diet in Children and Adolescents with Refractory Epilepsy-A Review.

Wells J, Swaminathan A, Paseka J, Hanson C · Nutrients · 2020-06-17

Clinical trial / intervention

505. Application of ketogenic diets for pediatric neurocritical care.

Lin KL, Lin JJ, Wang HS · Biomedical journal · 2020-07-05

Systematic review / meta-analysis

506. Use of ketogenic diet therapy in infants with epilepsy: A systematic review and meta-analysis.

Lyons L, Schoeler NE, Langan D, Cross JH · Epilepsia · 2020-05-26

Systematic review / meta-analysis

507. Ketogenic diet for the treatment of pediatric epilepsy: review and meta-analysis.

Sourbron J, Klinkenberg S, van Kuijk SMJ, Lagae L, Lambrechts D, Braakman HMH, Majoie M · Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2020-03-16

Clinical trial / intervention

508. The ketogenic diet all grown up-Ketogenic diet therapies for adults.

Husari KS, Cervenka MC · Epilepsy research · 2020-03-10

Review

509. Not your parents' ketogenic diet - Flexibility in 2020.

Blackford R · Epilepsy research · 2020-03-04

Review

510. Role of the ketogenic diet in acute neurological diseases.

Arora N, Mehta TR · Clinical neurology and neurosurgery · 2020-02-15

Other

511. Ketogenic Dietary Therapy Controversies for Its Second Century.

Kossoff E, Cervenka M · Epilepsy currents · 2019-12-02

Clinical trial / intervention

512. The 'epileptic diet'- ketogenic and/or slow release of glucose intervention: A review.

Qi X, Tester RF · Clinical nutrition (Edinburgh, Scotland) · 2019-06-08

Other

513. Selenium and antioxidant levels in children with intractable epilepsy receiving ketogenic diet.

El-Rashidy OF, Youssef MM, Elgendy YG, Mohsen MA, Morsy SM, Dawh SA, Saad K · Acta neurologica Belgica · 2020-02-27

Case report / case series

514. Usefulness of Continuous Glucose Monitoring for Prevention and Early Detection of Hypoglycemia Caused by a Ketogenic Diet and Late Dumping Syndrome.

Morikawa M, Hara Y, Nakazawa Y, Inaba Y, Motobayashi M · Pediatric neurology · 2019-12-26

Observational human study

515. Effectiveness, retention, and safety of modified ketogenic diet in adults with epilepsy at a tertiary-care centre in the UK.

Green SF, Nguyen P, Kaalund-Hansen K, Rajakulendran S, Murphy E · Journal of neurology · 2020-01-10

Case report / case series

516. Clinical Reasoning: Ketogenic diet in adult super-refractory status epilepticus.

Noviawaty I, Olaru E, Rondello C, Fitzsimmons B, Raghavan M · Neurology · 2020-02-27

Case report / case series

517. A girl with protein-losing enteropathy during a ketogenic diet: a case report.

Wang J, Jiang L, Cheng M · BMC pediatrics · 2020-03-03

Other

518. Biochemical assessment of patients following ketogenic diets for epilepsy: Current practice in the UK and Ireland.

Schoeler NE, Simpson Z, Whiteley VJ, Nguyen P, Meskell R, Lightfoot K, Martin-McGill KJ, Olpin S, Ivison F, Ketogenic Dietitians Research Network (KDRN) · Epilepsia open · 2019-11-29

Systematic review / meta-analysis

519. Systematic review of ketogenic diet use in adult patients with status epilepticus.

Mahmoud SH, Ho-Huang E, Buhler J · Epilepsia open · 2019-11-24

Preclinical / mechanistic

520. Preclinical testing of the ketogenic diet in fragile X mice.

Westmark PR, Gutierrez A, Gholston AK, Wilmer TM, Westmark CJ · Neurochemistry international · 2020-01-17

Review

521. Ketogenic diets and protective mechanisms in epilepsy, metabolic disorders, cancer, neuronal loss, and muscle and nerve degeneration.

Li RJ, Liu Y, Liu HQ, Li J · Journal of food biochemistry · 2020-01-14

Other

522. Editorial: Ketogenic Diet in Epilepsy and Associated Comorbidities: Clinical Efficacy and Mechanisms.

Li T, Qin J, Chu XP · Frontiers in neurology · 2020-02-19

Randomized clinical trial

523. Cardiometabolic risk and effectiveness of the modified Atkins Ketogenic Diet for adult patients with pharmacoresistant epilepsies in a middle-income country.

de Souza Neves G, Dos Santos Lunardi M, Papini Gabiatti M, Kurrle Rieger Venske D, Ribeiro LC, Lin K, Dubois Moreira J · Epilepsy research · 2020-01-16

Observational human study

524. The Ketogenic Diet Including Breast Milk for Treatment of Infants with Severe Childhood Epilepsy: Feasibility, Safety, and Effectiveness.

Dressler A, Häfele C, Giordano V, Benninger F, Trimmel-Schwahofer P, Gröppel G, Samueli S, Feucht M, Male C, Repa A · Breastfeeding medicine : the official journal of the Academy of Breastfeeding Medicine · 2019-11-26

Case report / case series

525. Accuracy of Flash Glucose Monitoring in a Patient with Dravet Syndrome on a Ketogenic Diet.

Kortas A, Schiller K, Unterholzner G, Rauchenzauner M · Neuropediatrics · 2019-09-17

Case report / case series

526. Modified Atkins Diet with slow reduction of carbohydrate.

Gauthier A, Simic N, Jones KC, RamachandranNair R · Epilepsy & behavior reports · 2019-12-19

Preclinical / mechanistic

527. Magnesium Supplementation did not affect the Antiseizure Property of Ketogenic Diet but Reduced Lipid Dysmetabolism.

Sanya EO, Adeyanju OA, Olarinoye JK, Bello H, Alaofin WA, Wahab KW, Soladoye AA · West African journal of medicine · 2020-02-08

Case report / case series

528. Monocarboxylate transporter-1 deficiency results in severe metabolic acidosis with ketogenic diet in early onset absence epilepsy: Case report.

Le A, Yeganeh M, Buhas D, Trempe MJ, Myers KA · Seizure · 2019-11-28

Randomized clinical trial

529. Potassium citrate and metabolic acidosis in children with epilepsy on the ketogenic diet: a prospective controlled study.

Bjurulf B, Magnus P, Hallböök T, Strømme P · Developmental medicine and child neurology · 2019-11-19

Observational human study

530. A Switch to Polyunsaturated Fatty Acid Based Ketogenic Diet Improves Seizure Control in Patients with Drug-resistant Epilepsy on the Mixed Fat Ketogenic Diet: A Retrospective Open Label Trial.

Nathan J, Bailur S, Datay K, Sharma S, Khedekar Kale D · Cureus · 2019-12-16

Observational human study

531. Ketogenic Diet for Refractory Childhood Epilepsy: Beyond Seizures Control, the Experience of a Portuguese Pediatric Centre.

Romão Luz I, Pereira C, Garcia P, Ferreira F, Faria A, Macedo C, Diogo L, Robalo C · Acta medica portuguesa · 2019-12-02

Observational human study

532. The Ketogenic Diet and Its Effect on Bone Mineral Density: A Retrospective Observational Cohort Study.

Draaisma JMT, Hampsink BM, Janssen M, van Houdt NBM, Linders ETAM, Willemsen MA · Neuropediatrics · 2019-08-09

Other

533. Benefits of a Ketogenic Teaching Kitchen.

Fenton C, Groveman S, Chee CM, Bergqvist AGC · Journal of child neurology · 2019-08-08

Observational human study

534. Medium-chain triglyceride ketogenic diet is effective for treatment of an adult with super-refractory status epilepticus: a case report and literature review.

Prasoppokakorn T, Jirasakuldej S, Lakananurak N · European journal of clinical nutrition · 2019-07-17

Guideline / consensus

535. [Consensus on ketogenic diet therapy for epilepsy and related nervous system diseases].

Subspecialty Group of Neurology, the Society of Pediatrics, Chinese Medical Association, China Association Against Epilepsy, Editorial Board, Chinese Journal of Pediatrics · Zhonghua er ke za zhi = Chinese journal of pediatrics · 2019-11-01

Clinical trial / intervention

536. Pharmacokinetic interaction between modified Atkins diet and antiepileptic drugs in adults with drug-resistant epilepsy.

Kverneland M, Taubøll E, Molteberg E, Veierød MB, Selmer KK, Nakken KO, Iversen PO · Epilepsia · 2019-10-10

Clinical trial / intervention

537. Lessons learned from recent clinical trials of ketogenic diet therapies in adults.

McDonald TJW, Cervenka MC · Current opinion in clinical nutrition and metabolic care · 2019-09-11

Randomized clinical trial

538. Ketogenic Diet and Epilepsy.

Ułamek-Kozioł M, Czuczwar SJ, Januszewski S, Pluta R · Nutrients · 2019-10-18

Review

539. Ketone Administration for Seizure Disorders: History and Rationale for Ketone Esters and Metabolic Alternatives.

Poff AM, Rho JM, D'Agostino DP · Frontiers in neuroscience · 2019-10-15

Other

540. Effects of a Formula-Based Ketogenic Diet on Refractory Epilepsy in 1 to 3 Year-Old Patients under Classic Ketogenic Diet.

Karimzadeh P, Moosavian T, Moosavian HR · Iranian journal of child neurology · 2018-09-29

Other

541. Ketogenic parenteral nutrition in three paediatric patients with epilepsy with migrating focal seizures.

Armeno M, Verini A, Araujo MB, Reyes G, Caraballo RH · Epileptic disorders : international epilepsy journal with videotape · 2019-10-17

Other

542. The equivalence of the ketogenic diet and adrenocorticotropic hormone for treatment of infantile spasms: More suggestion than conclusion.

Hussain SA · Epilepsia · 2019-08-28

Other

543. In response: The equivalence of the ketogenic diet and adrenocorticotropic hormone for treatment of infantile spasms: More suggestion than conclusion.

Dressler A, Benninger F, Trimmel-Schwahofer P, Gröppel G, Porsche B, Abraham K, Mühlebner A, Samueli S, Male C, Feucht M · Epilepsia · 2019-08-28

Observational human study

544. Pediatric emergency department visit characteristics of the patients on the ketogenic diet.

Çağlar A, Edizer S, Sarıtaş S, Çelebi Çelik F, Önder M, Er A, Ulusoy E, Akgül F, Ünalp A, Yılmaz Ü, Apa H · Epilepsy & behavior : E&B · 2019-08-06

Clinical trial / intervention

545. Age and Ketogenic Diet Have Dissociable Effects on Synapse-Related Gene Expression Between Hippocampal Subregions.

Hernandez AR, Hernandez CM, Truckenbrod LM, Campos KT, McQuail JA, Bizon JL, Burke SN · Frontiers in aging neuroscience · 2019-09-13

Other

546. Outpatient initiation of the ketogenic diet.

Craiu DC · European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society · 2019-11-02

Observational human study

547. Outpatient initiation of the ketogenic diet in children with pharmacoresistant epilepsy: An effectiveness, safety and economic perspective.

van der Louw E, Olieman J, Poley MJ, Wesstein T, Vehmeijer F, Catsman-Berrevoets C, Neuteboom R · European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society · 2019-06-29

Other

548. The risk of hypoglycemia and the ketogenic diet for super-refractory status epilepticus patients.

Brožová K, Brož J · Brain & development · 2019-02-22

Preclinical / mechanistic

549. Bone microstructure and metabolism changes under the combined intervention of ketogenic diet with intermittent fasting: an in vivo study of rats.

Xu X, Ding J, Wu X, Huang Z, Kong G, Liu Q, Yang Z, Huang Z, Zhu Q · Experimental animals · 2019-04-03

Preclinical / mechanistic

550. The Impact of the Ketogenic Diet on Glial Cells Morphology. A Quantitative Morphological Analysis.

Gzielo K, Soltys Z, Rajfur Z, Setkowicz ZK · Neuroscience · 2019-06-18

Other

551. Absence of increased blood decanoic acid levels in children with epilepsy treated with classic ketogenic diet.

Enderlin J, Loussouarn A, Benoist JF, Dozières-Puyravel B, Auvin S · Epileptic disorders : international epilepsy journal with videotape · 2019-08-02

Case report / case series

552. Successful Management of Ketogenic Parenteral Nutrition: A Pediatric Case Study.

Lowe H, Segal S, Mouzaki M, Langos V, Dlamini N · JPEN. Journal of parenteral and enteral nutrition · 2018-12-20

Observational human study

553. Long-Term Effects of a Classic Ketogenic Diet on Ghrelin and Leptin Concentration: A 12-Month Prospective Study in a Cohort of Italian Children and Adults with GLUT1-Deficiency Syndrome and Drug Resistant Epilepsy.

De Amicis R, Leone A, Lessa C, Foppiani A, Ravella S, Ravasenghi S, Trentani C, Ferraris C, Veggiotti P, De Giorgis V, Tagliabue A, Battezzati A, Bertoli S · Nutrients · 2019-07-25

Other

554. Ghrelin Plasma Levels After 1 Year of Ketogenic Diet in Children With Refractory Epilepsy.

Marchiò M, Roli L, Lucchi C, Costa AM, Borghi M, Iughetti L, Trenti T, Guerra A, Biagini G · Frontiers in nutrition · 2019-07-24

Other

555. Quality of Life in Chronic Ketogenic Diet Treatment: The GLUT1DS Population Perspective.

Varesio C, Pasca L, Parravicini S, Zanaboni MP, Ballante E, Masnada S, Ferraris C, Bertoli S, Tagliabue A, Veggiotti P, De Giorgis V · Nutrients · 2019-07-19

Observational human study

556. A Prospective Study on Changes in Nutritional Status and Growth Following Two Years of Ketogenic Diet (KD) Therapy in Children with Refractory Epilepsy.

Armeno M, Verini A, Del Pino M, Araujo MB, Mestre G, Reyes G, Caraballo RH · Nutrients · 2019-07-14

Review

557. The Effects of Ketogenic Diet Treatment in Kcna1-Null Mouse, a Model of Sudden Unexpected Death in Epilepsy.

Ren Y, Chang J, Li C, Jia C, Li P, Wang Y, Chu XP · Frontiers in neurology · 2019-07-10

Review

558. A Journey of Dietary Therapies for Epilepsy in Iran: Diet Restriction in the Ancient Era to the Ketogenic Diet in the Modern Period.

Karimzadeh P, Tabrizi A · Iranian journal of child neurology · 2019-05-11

Other

559. Changes in tryptophan and kynurenine pathway metabolites in the blood of children treated with ketogenic diet for refractory epilepsy.

Żarnowska I, Wróbel-Dudzińska D, Tulidowicz-Bielak M, Kocki T, Mitosek-Szewczyk K, Gasior M, Turski WA · Seizure · 2019-05-09

Clinical trial / intervention

560. Prospective study of growth and bone mass in Swedish children treated with the modified Atkins diet.

Svedlund A, Hallböök T, Magnusson P, Dahlgren J, Swolin-Eide D · European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society · 2019-04-08

Review

561. Ketogenic dietary therapies for epilepsy and beyond.

deCampo DM, Kossoff EH · Current opinion in clinical nutrition and metabolic care · 2019-04-30

Observational human study

562. Initiating the ketogenic diet in infants with treatment refractory epilepsy while maintaining a breast milk diet.

Le Pichon JB, Thompson L, Gustafson M, Abdelmoity A · Seizure · 2019-03-26

Review

563. Effect of ketogenic diets on leukocyte counts in patients with epilepsy.

Schreck KC, Lwin M, Strowd RE, Henry-Barron BJ, Blakeley JO, Cervenka MC · Nutritional neuroscience · 2017-12-18

Observational human study

564. The ketogenic diet in children 3 years of age or younger: a 10-year single-center experience.

Kim SH, Shaw A, Blackford R, Lowman W, Laux LC, Millichap JJ, Nordli DR · Scientific reports · 2019-06-19

Observational human study

565. The Efficacy of Ketogenic Diet in 60 Chinese Patients With Dravet Syndrome.

Tian X, Chen J, Zhang J, Yang X, Ji T, Zhang Y, Wu Y, Fang F, Wu X, Zhang Y · Frontiers in neurology · 2019-06-13

Review

566. Ketone Bodies in Neurological Diseases: Focus on Neuroprotection and Underlying Mechanisms.

Yang H, Shan W, Zhu F, Wu J, Wang Q · Frontiers in neurology · 2019-06-12

Review

567. Crosstalk between the Ketogenic Diet and Epilepsy: From the Perspective of Gut Microbiota.

Fan Y, Wang H, Liu X, Zhang J, Liu G · Mediators of inflammation · 2019-06-03

Guideline / consensus

568. Understanding the core principles of a 'modified ketogenic diet': a UK and Ireland perspective.

Martin-McGill KJ, Lambert B, Whiteley VJ, Wood S, Neal EG, Simpson ZR, Schoeler NE, Ketogenic Dietitians Research Network (KDRN) · Journal of human nutrition and dietetics : the official journal of the British Dietetic Association · 2019-03-11

Other

569. A Proof-of-Principle, Case-Control Study to Compensate for Potential Carbohydrates in Liquid Antiseizure Drugs in Children on the Ketogenic Diet.

Haney CA, Charpentier A, Turner Z, Bessone SK, Doerrer SC, Kossoff EH · Journal of child neurology · 2019-02-20

Other

570. Ketogenic Diet in Epilepsy of Infancy With Migrating Focal Seizures.

Madaan P, Jauhari P, Chakrabarty B, Gulati S · Pediatric neurology · 2019-01-07

Randomized clinical trial

571. The Feasibility, Safety and Effectiveness of a Ketogenic Diet for Refractory Status Epilepticus in Adults in the Intensive Care Unit.

Francis BA, Fillenworth J, Gorelick P, Karanec K, Tanner A · Neurocritical care · 2018-11-30

Case report / case series

572. Ketogenic diet, a potentially valuable therapeutic option for the management of refractory epilepsy in classical neonatal nonketotic hyperglycinemia: a case report.

Kava MP, Robertson A, Greed L, Balasubramaniam S · European journal of clinical nutrition · 2018-08-14

Clinical trial / intervention

573. Food and Food Products on the Italian Market for Ketogenic Dietary Treatment of Neurological Diseases.

Leone A, De Amicis R, Lessa C, Tagliabue A, Trentani C, Ferraris C, Battezzati A, Veggiotti P, Foppiani A, Ravella S, Bertoli S · Nutrients · 2019-05-17

Observational human study

574. Optimized mid-long term management of ketogenic diet in children with refractory epilepsy.

Sheng GM, Yin P, Lv M, Zhu YH, Li BM, Lei GF, Liu H · Journal of biological regulators and homeostatic agents · 2019-06-18

Case report / case series

575. Treatment of myoclonic-atonic epilepsy caused by SLC2A1 de novo mutation with ketogenic diet: A case report.

Wei Z, Wang L, Deng Y · Medicine · 2019-05-03

Clinical trial / intervention

576. Outcome measurement and reporting in childhood epilepsy treated with ketogenic diet therapy: a scoping review protocol.

Carroll J, Martin-McGill K, Cross H, Hickson M, Collinson A · JBI database of systematic reviews and implementation reports · 2019-03-20

Observational human study

577. Failure of ketogenic diet therapy in GLUT1 deficiency syndrome.

Bekker YAC, Lambrechts DA, Verhoeven JS, van Boxtel J, Troost C, Kamsteeg EJ, Willemsen MA, Braakman HMH · European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society · 2019-02-27

Review

578. The Ketogenic and Modified Atkins Diet Therapy for Children With Refractory Epilepsy of Genetic Etiology.

Jagadish S, Payne ET, Wong-Kisiel L, Nickels KC, Eckert S, Wirrell EC · Pediatric neurology · 2018-12-29

Observational human study

579. The ketogenic diet for super-refractory status epilepticus patients in intensive care units.

Park EG, Lee J, Lee J · Brain & development · 2019-01-09

Systematic review / meta-analysis

580. Short-term and long-term efficacy of classical ketogenic diet and modified Atkins diet in children and adolescents with epilepsy: A systematic review and meta-analysis.

Rezaei S, Abdurahman AA, Saghazadeh A, Badv RS, Mahmoudi M · Nutritional neuroscience · 2017-10-25

Observational human study

581. Ketogenic Diet as a Treatment for Super-Refractory Status Epilepticus in Febrile Infection-Related Epilepsy Syndrome.

Peng P, Peng J, Yin F, Deng X, Chen C, He F, Wang X, Guang S, Mao L · Frontiers in neurology · 2019-04-26

Preclinical / mechanistic

582. Bone loss and biomechanical reduction of appendicular and axial bones under ketogenic diet in rats.

Ding J, Xu X, Wu X, Huang Z, Kong G, Liu J, Huang Z, Liu Q, Li R, Yang Z, Liu Y, Zhu Q · Experimental and therapeutic medicine · 2019-02-04

Preclinical / mechanistic

583. The effect of ketogenic diet on behaviors and synaptic functions of naive mice.

Huang J, Li YQ, Wu CH, Zhang YL, Zhao ST, Chen YJ, Deng YH, Xuan A, Sun XD · Brain and behavior · 2019-03-07

Clinical trial / intervention

584. How often is antiseizure drug-free ketogenic diet therapy achieved?

Shah LM, Turner Z, Bessone SK, Winesett SP, Stanfield A, Kossoff EH · Epilepsy & behavior : E&B · 2019-03-01

Clinical trial / intervention

585. Do certain subpopulations of adults with drug-resistant epilepsy respond better to modified ketogenic diet treatments? Evaluation based on prior resective surgery, type of epilepsy, imaging abnormalities, and vagal nerve stimulation.

Falco-Walter JJ, Roehl K, Ouyang B, Balabanov A · Epilepsy & behavior : E&B · 2019-02-07

Preclinical / mechanistic

586. Ketogenic and anaplerotic dietary modifications ameliorate seizure activity in Drosophila models of mitochondrial encephalomyopathy and glycolytic enzymopathy.

Fogle KJ, Smith AR, Satterfield SL, Gutierrez AC, Hertzler JI, McCardell CS, Shon JH, Barile ZJ, Novak MO, Palladino MJ · Molecular genetics and metabolism · 2019-01-17

Case report / case series

587. Ketogenic diet as a successful early treatment modality for SCN2A mutation.

Turkdogan D, Thomas G, Demirel B · Brain & development · 2018-11-08

Observational human study

588. Decreased ghrelin and des-acyl ghrelin plasma levels in patients affected by pharmacoresistant epilepsy and maintained on the ketogenic diet.

Marchiò M, Roli L, Giordano C, Trenti T, Guerra A, Biagini G · Clinical nutrition (Edinburgh, Scotland) · 2018-03-23

Preclinical / mechanistic

589. Time of Day and a Ketogenic Diet Influence Susceptibility to SUDEP in Scn1a R1407X/+ Mice.

Teran FA, Kim Y, Crotts MS, Bravo E, Emaus KJ, Richerson GB · Frontiers in neurology · 2019-03-29

Systematic review / meta-analysis

590. Three and Six Months of Ketogenic Diet for Intractable Childhood Epilepsy: A Systematic Review and Meta-Analysis.

Liu XY, Chen J, Zhu M, Zheng G, Guo H, Lu X, Wang X, Yang X · Frontiers in neurology · 2019-03-15

Preclinical / mechanistic

591. Ketone Bodies Inhibit the Opening of Acid-Sensing Ion Channels (ASICs) in Rat Hippocampal Excitatory Neurons in vitro.

Zhu F, Shan W, Xu Q, Guo A, Wu J, Wang Q · Frontiers in neurology · 2019-03-12

Observational human study

592. Efficacy of the ketogenic diet in Chinese children with Dravet syndrome: A focus on neuropsychological development.

Liu F, Peng J, Zhu C, Xiao H, He F, Yin F, Chen C · Epilepsy & behavior : E&B · 2019-01-12

Review

593. Role of DNA Methylation and Adenosine in Ketogenic Diet for Pharmacoresistant Epilepsy: Focus on Epileptogenesis and Associated Comorbidities.

Chen F, He X, Luan G, Li T · Frontiers in neurology · 2019-02-26

Preclinical / mechanistic

594. Neuro-Behavioral Status and the Hippocampal Expression of Metabolic Associated Genes in Wild-Type Rat Following a Ketogenic Diet.

Ling Y, Wang DD, Sun YX, Zhao DJ, Ni H · Frontiers in neurology · 2019-02-05

Review

595. Ketogenic Diet and Epilepsy: What We Know So Far.

D'Andrea Meira I, Romão TT, Pires do Prado HJ, Krüger LT, Pires MEP, da Conceição PO · Frontiers in neuroscience · 2019-01-29

Clinical trial / intervention

596. The ketogenic diet influences taxonomic and functional composition of the gut microbiota in children with severe epilepsy.

Lindefeldt M, Eng A, Darban H, Bjerkner A, Zetterström CK, Allander T, Andersson B, Borenstein E, Dahlin M, Prast-Nielsen S · NPJ biofilms and microbiomes · 2019-01-23

Review

597. Metabolism and epilepsy: Ketogenic diets as a homeostatic link.

Masino SA, Rho JM · Brain research · 2018-06-06

Review

598. [Multidisciplinary teamwork in the clinical application of the ketogenic diet].

Fasulo L, Semprino M, Caraballo R · Medicina · 2019-07-09

Case report / case series

599. Implementation of ketogenic diet in children with drug-resistant epilepsy in a medium resources setting: Egyptian experience.

Gerges M, Selim L, Girgis M, El Ghannam A, Abdelghaffar H, El-Ayadi A · Epilepsy & behavior case reports · 2018-11-23

Guideline / consensus

600. Yield of laboratory testing in pediatric ketogenic diet patients: Critical assessment of abnormal results and impact on clinical care.

Joshi C, Stillman C, Criteser S, Oliver J, Conley A, Sillau S, Zupec-Kania B · Epilepsy research · 2018-11-16

Clinical trial / intervention

601. Efficacy and tolerability of olive oil-based ketogenic diet in children with drug-resistant epilepsy: A single center experience from Turkey.

Guzel O, Uysal U, Arslan N · European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society · 2018-11-20

Preclinical / mechanistic

602. A Ketogenic Diet Improves Mitochondrial Biogenesis and Bioenergetics via the PGC1α-SIRT3-UCP2 Axis.

Hasan-Olive MM, Lauritzen KH, Ali M, Rasmussen LJ, Storm-Mathisen J, Bergersen LH · Neurochemical research · 2018-07-19

Preclinical / mechanistic

603. Preventive effects of ketone ester BD-AcAc2 on central nervous system oxygen toxicity and concomitant acute lung injury.

Yi H, Yu S, Zhang Y, Li R, Zhang D, Zhang D, Xu W · Diving and hyperbaric medicine · 2018-08-09

Case report / case series

604. Efficacy of ketogenic diet for pyruvate dehydrogenase complex deficiency.

Chida R, Shimura M, Nishimata S, Kashiwagi Y, Kawashima H · Pediatrics international : official journal of the Japan Pediatric Society · 2018-11-08

Observational human study

605. Use of cooking oils in a 2:1 ratio classical ketogenic diet for intractable pediatric epilepsy: Long-term effectiveness and tolerability.

Lee HF, Chi CS, Liao JH · Epilepsy research · 2018-09-12

Preclinical / mechanistic

606. Ketogenic diet regulates the antioxidant catalase via the transcription factor PPARγ2.

Knowles S, Budney S, Deodhar M, Matthews SA, Simeone KA, Simeone TA · Epilepsy research · 2018-09-21

Other

607. Guiding Ketogenic Diet with Breath Acetone Sensors.

Güntner AT, Kompalla JF, Landis H, Theodore SJ, Geidl B, Sievi NA, Kohler M, Pratsinis SE, Gerber PA · Sensors (Basel, Switzerland) · 2018-10-28

Other

608. Gut Microbes May Account for the Anti-Seizure Effects of the Ketogenic Diet.

Hampton T · JAMA · 2018-10-05

Systematic review / meta-analysis

609. Cognitive benefits of the ketogenic diet in patients with epilepsy: A systematic overview.

van Berkel AA, IJff DM, Verkuyl JM · Epilepsy & behavior : E&B · 2018-08-31

Other

610. Question 1: Is there a role for the ketogenic diet in refractory status epilepticus?

Fessas P, Duret A · Archives of disease in childhood · 2018-08-13

Observational human study

611. Effect of Ketogenic Diet on Motor Functions and Daily Living Activities of Children With Multidrug-Resistant Epilepsy: A Prospective Study.

Çubukçu D, Güzel O, Arslan N · Journal of child neurology · 2018-07-31

Other

612. Ketogenic diet and avoidance of mitochondrion-toxic AEDs may improve the outcome of mitochondrial epilepsy.

Finsterer J, Zarrouk-Mahjoub S · Clinical neurology and neurosurgery · 2018-02-22

Other

613. Gut Microbiota, the Ketogenic Diet and Epilepsy.

Spinelli E, Blackford R · Pediatric neurology briefs · 2018-09-21

Observational human study

614. Altered gut microbiome composition in children with refractory epilepsy after ketogenic diet.

Zhang Y, Zhou S, Zhou Y, Yu L, Zhang L, Wang Y · Epilepsy research · 2018-06-28

Clinical trial / intervention

615. Metabolic perturbations associated with the consumption of a ketogenic medium-chain TAG diet in dogs with idiopathic epilepsy.

Law TH, Volk HA, Pan Y, Zanghi B, Want EJ · The British journal of nutrition · 2018-07-13

Case report / case series

616. SCN2A mutation in an infant presenting with migrating focal seizures and infantile spasm responsive to a ketogenic diet.

Su DJ, Lu JF, Lin LJ, Liang JS, Hung KL · Brain & development · 2018-04-04

Preclinical / mechanistic

617. Ketogenic Diet Modulates NAD+-Dependent Enzymes and Reduces DNA Damage in Hippocampus.

Elamin M, Ruskin DN, Masino SA, Sacchetti P · Frontiers in cellular neuroscience · 2018-08-30

Observational human study

618. Prospective study of the efficacy of a ketogenic diet in 20 patients with Dravet syndrome.

Yan N, Xin-Hua W, Lin-Mei Z, Yi-Ming C, Wen-Hui L, Yuan-Feng Z, Shui-Zhen Z · Seizure · 2018-06-30

Randomized clinical trial

619. Improving compliance in adults with epilepsy on a modified Atkins diet: A randomized trial.

McDonald TJW, Henry-Barron BJ, Felton EA, Gutierrez EG, Barnett J, Fisher R, Lwin M, Jan A, Vizthum D, Kossoff EH, Cervenka MC · Seizure · 2018-06-22

Randomized clinical trial

620. Effect of modified Atkins diet in adults with drug-resistant focal epilepsy: A randomized clinical trial.

Kverneland M, Molteberg E, Iversen PO, Veierød MB, Taubøll E, Selmer KK, Nakken KO · Epilepsia · 2018-06-14

Other

621. Efficacy and safety of ketogenic diet for treatment of pediatric convulsive refractory status epilepticus.

Arya R, Peariso K, Gaínza-Lein M, Harvey J, Bergin A, Brenton JN, Burrows BT, Glauser T, Goodkin HP, Lai YC, Mikati MA, Fernández IS, Tchapyjnikov D, Wilfong AA, Williams K, Loddenkemper T, pediatric Status Epilepticus Research Group (pSERG) · Epilepsy research · 2018-04-27

Review

622. The ketogenic diet in disease and development.

Barry D, Ellul S, Watters L, Lee D, Haluska R, White R · International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience · 2018-04-22

Observational human study

623. The Efficacy of Ketogenic Diet for Specific Genetic Mutation in Developmental and Epileptic Encephalopathy.

Ko A, Jung DE, Kim SH, Kang HC, Lee JS, Lee ST, Choi JR, Kim HD · Frontiers in neurology · 2018-07-16

Review

624. Electrical Control in Neurons by the Ketogenic Diet.

Sada N, Inoue T · Frontiers in cellular neuroscience · 2018-07-16

Other

625. The Gut Microbiota Mediates the Anti-Seizure Effects of the Ketogenic Diet.

Olson CA, Vuong HE, Yano JM, Liang QY, Nusbaum DJ, Hsiao EY · Cell · 2018-07-16

Other

626. Ketogenic Diet an Option for Treating Uncontrolled Epilepsy.

Mullins S, Bean SC, Abrahams J · American family physician · 2018-09-15

Other

627. Corrigendum to "Complications During Ketogenic Diet Initiation: Prevalence, Treatment and Influence on Seizure Outcomes" [Pediatr Neurol. 68 (2017) 35-39].

Lin A, Turner Z, Doerrer SC, Stanfield A, Kossoff EH · Pediatric neurology · 2018-05-10

Other

628. β-Hydroxybutyrate Detection with Proton MR Spectroscopy in Children with Drug-Resistant Epilepsy on the Ketogenic Diet.

Wright JN, Saneto RP, Friedman SD · AJNR. American journal of neuroradiology · 2018-05-03

Other

629. Prediction of responders to ketogenic diet based on syndrome and etiology: identification of a new target population?

Auvin S · Developmental medicine and child neurology · 2018-03-22

Other

630. The ketogenic diet is effective for refractory epilepsy associated with acquired structural epileptic encephalopathy.

Villaluz MM, Lomax LB, Jadhav T, Cross JH, Scheffer IE · Developmental medicine and child neurology · 2018-02-16

Observational human study

631. Use of the Modified Atkins Diet in Intractable Pediatric Epilepsy.

Park EG, Lee J, Lee J · Journal of epilepsy research · 2018-06-30

Clinical trial / intervention

632. Therapeutic augmentation of ketogenic diet with a sodium-glucose cotransporter 2 inhibitor in a super-refractory status epilepticus patient.

Blunck JR, Newman JW, Fields RK, Croom JE · Epilepsy & behavior case reports · 2018-06-20

Other

633. Breath profiles of children on ketogenic therapy.

Ruzsányi V, Péter Kalapos M, Schmidl C, Karall D, Scholl-Bürgi S, Baumann M · Journal of breath research · 2018-06-08

Preclinical / mechanistic

634. Regulation of kynurenine metabolism by a ketogenic diet.

Heischmann S, Gano LB, Quinn K, Liang LP, Klepacki J, Christians U, Reisdorph N, Patel M · Journal of lipid research · 2018-03-31

Observational human study

635. Ketogenic Diet in Refractory Childhood Epilepsy: Starting With a Liquid Formulation in an Outpatient Setting.

Weijenberg A, van Rijn M, Callenbach PMC, de Koning TJ, Brouwer OF · Child neurology open · 2018-05-29

Other

636. [Treatment with neurostimulation and ketogenic diet for people with medically refractory epilepsy].

Kumlien E, Hallbook T, Dahlin M · Lakartidningen · 2018-05-22

Observational human study

637. Ketogenic diet effects on 52 children with pharmacoresistant epileptic encephalopathy: A clinical prospective study.

Wu Q, Wang H, Fan YY, Zhang JM, Liu XY, Fang XY, Yang FH, Cao QJ, Qi Y · Brain and behavior · 2018-04-18

Case report / case series

638. Copper Deficiency Anemia and Neutropenia Due to Ketogenic Diet.

Chin A · Pediatrics · 2017-12-18

Clinical trial / intervention

639. A pragmatic study on efficacy, tolerability and long term acceptance of ketogenic diet therapy in 74 South Indian children with pharmacoresistant epilepsy.

Baby N, Vinayan KP, Pavithran N, Grace Roy A · Seizure · 2018-03-21

Case report / case series

640. ATP1A3-related epileptic encephalopathy responding to ketogenic diet.

Schirinzi T, Graziola F, Cusmai R, Fusco L, Nicita F, Elia M, Travaglini L, Bertini E, Curatolo P, Vigevano F, Capuano A · Brain & development · 2018-02-01

Review

641. Do ketone bodies mediate the anti-seizure effects of the ketogenic diet?

Simeone TA, Simeone KA, Stafstrom CE, Rho JM · Neuropharmacology · 2018-01-08

Observational human study

642. Ketogenic diet use in children with intractable epilepsy secondary to malformations of cortical development: A two- centre experience.

Pasca L, Caraballo RH, De Giorgis V, Reyes JG, Macasaet JA, Masnada S, Armeno M, Musicco M, Tagliabue A, Veggiotti P · Seizure · 2018-03-08

Observational human study

643. Ketogenic diet therapy in infants less than two years of age for medically refractory epilepsy.

Ismayilova N, Leung MA, Kumar R, Smith M, Williams RE · Seizure · 2018-03-02

Other

644. Ketogenic Therapy: First-Line Management of Intractable Seizures in Children.

Williams L · AACN advanced critical care · 2018-03-03

Review

645. [Update on the adverse effects during therapy with a ketogenic diet in paediatric refractory epilepsy].

Armeno M, Araujo C, Sotomontesano B, Caraballo RH · Revista de neurologia · 2018-03-15

Preclinical / mechanistic

646. The Antiepileptic Ketogenic Diet Alters Hippocampal Transporter Levels and Reduces Adiposity in Aged Rats.

Hernandez AR, Hernandez CM, Campos KT, Truckenbrod LM, Sakarya Y, McQuail JA, Carter CS, Bizon JL, Maurer AP, Burke SN · The journals of gerontology. Series A, Biological sciences and medical sciences · 2017-07-11

Review

647. [The effects of ketogenic diet are numerous].

Møhl T, Miranda MJ · Ugeskrift for laeger · 2018-03-15

Other

648. [Intravenous ketogenic diet for super-refractory status epilepticus in a case].

Peng P, Deng XL, Yang LF · Zhonghua er ke za zhi = Chinese journal of pediatrics · 2018-03-10

Other

649. Ketogenic parenteral nutrition in 17 pediatric patients with epilepsy.

Dressler A, Haiden N, Trimmel-Schwahofer P, Benninger F, Samueli S, Gröppel G, Spatzierer S, Mühlebner A, Abraham K, Feucht M · Epilepsia open · 2017-11-16

Preclinical / mechanistic

650. Indispensable Amino Acid-Deficient Diets Induce Seizures in Ketogenic Diet-Fed Rodents, Demonstrating a Role for Amino Acid Balance in Dietary Treatments for Epilepsy.

Gietzen DW, Lindström SH, Sharp JW, Teh PS, Donovan MJ · The Journal of nutrition · 2017-07-04

Randomized clinical trial

651. [Epilepsy, cognition and ketogenic diet].

Garcia-Penas JJ · Revista de neurologia · 2018-03-09

Observational human study

652. Ketogenic diet using a Japanese ketogenic milk for patients with epilepsy: A multi-institutional study.

Kumada T, Imai K, Takahashi Y, Nabatame S, Oguni H · Brain & development · 2017-11-26

Randomized clinical trial

653. Ketogenic Diet Based on Extra Virgin Coconut Oil Has No Effects in Young Wistar Rats With Pilocarpine-Induced Epilepsy.

Melo IT, M Rêgo E, Bueno NB, Gomes TC, Oliveira SL, Trindade-Filho EM, Cabral CR, Machado TS, Galvão JA, R Ataide T · Lipids · 2018-03-23

Preclinical / mechanistic

654. Ketogenic diet-induced extension of longevity in epileptic Kcna1-null mice is influenced by gender and age at treatment onset.

Chun KC, Ma SC, Oh H, Rho JM, Kim DY · Epilepsy research · 2017-11-21

Other

655. [Mechanisms of ketogenic diet action].

Tiulganova DA, Nasaev SS, Chugreev IA, Rodionova MA, Zavyalov GA · Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova · 2019-01-31

Other

656. An mHealth Application for Educating and Monitoring Patients Treated with a Ketogenic Diet Regimen.

Zini EM, Tagliabue A, Trentani C, Ferraris C, Boninsegna R, Quaglini S, Lanzola G · Studies in health technology and informatics · 2018-04-22

Other

657. A randomized controlled trial of the ketogenic diet in refractory childhood epilepsy.

Lambrechts DAJE, de Kinderen RJA, Vles JSH, de Louw AJA, Aldenkamp AP, Majoie HJM · Acta neurologica Scandinavica · 2017-12-06

Preclinical / mechanistic

658. Inhibition of monoacylglycerol lipase terminates diazepam-resistant status epilepticus in mice and its effects are potentiated by a ketogenic diet.

Terrone G, Pauletti A, Salamone A, Rizzi M, Villa BR, Porcu L, Sheehan MJ, Guilmette E, Butler CR, Piro JR, Samad TA, Vezzani A · Epilepsia · 2017-11-24

Observational human study

659. Prevalence of Genetic Disorders and GLUT1 Deficiency in a Ketogenic Diet Clinic.

Hewson S, Brunga L, Ojeda MF, Imhof E, Patel J, Zak M, Donner EJ, Kobayashi J, Salomons GS, Mercimek-Andrews S · The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques · 2017-11-16

Preclinical / mechanistic

660. Ketogenic diet attenuates neuronal injury via autophagy and mitochondrial pathways in pentylenetetrazol-kindled seizures.

Wang BH, Hou Q, Lu YQ, Jia MM, Qiu T, Wang XH, Zhang ZX, Jiang Y · Brain research · 2017-10-19

Observational human study

661. Analysis of hematological parameters in patients treated with ketogenic diet due to drug-resistant epilepsy.

Kose E, Guzel O, Arslan N · Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2017-10-16

Review

662. The Anticonvulsant Effects of Ketogenic Diet on Epileptic Seizures and Potential Mechanisms.

Zhang Y, Xu J, Zhang K, Yang W, Li B · Current neuropharmacology · 2017-04-09

Other

663. Longitudinal Change in Thyroid Hormone Levels in Children with Epilepsy on a Ketogenic Diet: Prevalence and Risk Factors.

Lee YJ, Nam SO, Kim KM, Kim YM, Yeon GM · Journal of epilepsy research · 2017-12-31

Systematic review / meta-analysis

664. Safety and tolerability of the ketogenic diet used for the treatment of refractory childhood epilepsy: a systematic review of published prospective studies.

Cai QY, Zhou ZJ, Luo R, Gan J, Li SP, Mu DZ, Wan CM · World journal of pediatrics : WJP · 2017-07-12

Other

665. Effect of ketogenic diet and other dietary therapies on anti-epileptic drug concentrations in patients with epilepsy.

Heo G, Kim SH, Chang MJ · Journal of clinical pharmacy and therapeutics · 2017-06-18

Review

666. Ketogenic Diets for Adults With Highly Refractory Epilepsy.

McDonald TJW, Cervenka MC · Epilepsy currents · 2017-12-09

Other

667. Ketogenic Diet in Super-Refractory Status Epilepticus.

Smith G, Press CA · Pediatric neurology briefs · 2017-11-30

Other

668. Development and pilot testing of a parent-reported health-related quality of life measure for children on the ketogenic diet: The KetoQoL.

Barwick K, Parker T, Murphy N, Todd A, Leveritt M, Wilkinson SA · Nutrition & dietetics : the journal of the Dietitians Association of Australia · 2017-04-12

Case report / case series

669. Severe Neutropenia and Anemia in a Child With Epilepsy and Copper Deficiency on a Ketogenic Diet.

Rashidian H, Liu YMC, Geraghty MT, Kobayashi J, Donner EJ, Klaassen RJ · Pediatric neurology · 2017-08-24

Randomized clinical trial

670. The modified ketogenic diet for adults with refractory epilepsy: An evaluation of a set up service.

Martin-McGill KJ, Jenkinson MD, Tudur Smith C, Marson AG · Seizure · 2017-09-01

Clinical trial / intervention

671. Electrographic Changes Accompanying Recurrent Seizures under Ketogenic Diet Treatment.

Lucchi C, Marchiò M, Caramaschi E, Giordano C, Giordano R, Guerra A, Biagini G · Pharmaceuticals (Basel, Switzerland) · 2017-10-20

Review

672. Ketogenic diet in endocrine disorders: Current perspectives.

Gupta L, Khandelwal D, Kalra S, Gupta P, Dutta D, Aggarwal S · Journal of postgraduate medicine · 2017-10-13

Observational human study

673. The effect of the ketogenic diet on the developing skeleton.

Simm PJ, Bicknell-Royle J, Lawrie J, Nation J, Draffin K, Stewart KG, Cameron FJ, Scheffer IE, Mackay MT · Epilepsy research · 2017-07-26

Clinical trial / intervention

674. The ketogenic diet in patients with myoclonic status in non-progressive encephalopathy.

Caraballo R, Darra F, Reyes G, Armeno M, Cresta A, Mestre G, Bernardina BD · Seizure · 2017-07-11

Other

675. Ketogenic diet poses a significant effect on imbalanced gut microbiota in infants with refractory epilepsy.

Xie G, Zhou Q, Qiu CZ, Dai WK, Wang HP, Li YH, Liao JX, Lu XG, Lin SF, Ye JH, Ma ZY, Wang WJ · World journal of gastroenterology · 2017-04-24

Other

676. Ketogenic Diet: It Has a Role in Our Armamentarium of Treatment of Refractory Seizures.

Pack AM · Epilepsy currents · 2017-12-12

Review

677. An acidosis-sparing ketogenic (ASK) diet to improve efficacy and reduce adverse effects in the treatment of refractory epilepsy.

Yuen AWC, Walcutt IA, Sander JW · Epilepsy & behavior : E&B · 2017-06-28

Review

678. Practice Paper of the Academy of Nutrition and Dietetics: Classic and Modified Ketogenic Diets for Treatment of Epilepsy.

Roehl K, Sewak SL · Journal of the Academy of Nutrition and Dietetics · 2017-06-05

Other

679. Use of the ketogenic diet to manage refractory epilepsy in CDKL5 disorder: Experience of >100 patients.

Lim Z, Wong K, Olson HE, Bergin AM, Downs J, Leonard H · Epilepsia · 2017-06-12

Preclinical / mechanistic

680. Synergistic protection against acute flurothyl-induced seizures by adjuvant treatment of the ketogenic diet with the type 2 diabetes drug pioglitazone.

Simeone TA, Matthews SA, Simeone KA · Epilepsia · 2017-05-28

Other

681. Impact of Child Life Services on Children and Families Admitted to Start the Ketogenic Diet.

Kossoff EH, Sutter L, Doerrer SC, Haney CA, Turner Z · Journal of child neurology · 2017-05-08

Other

682. What is a ketogenic diet and how does it affect the use of medicines?

McArtney R, Bailey A, Champion H · Archives of disease in childhood. Education and practice edition · 2016-07-28

Other

683. Non-ketogenic combination of nutritional strategies provides robust protection against seizures.

Dallérac G, Moulard J, Benoist JF, Rouach S, Auvin S, Guilbot A, Lenoir L, Rouach N · Scientific reports · 2017-07-14

Preclinical / mechanistic

684. Reduction of epileptiform activity in ketogenic mice: The role of monocarboxylate transporters.

Forero-Quintero LS, Deitmer JW, Becker HM · Scientific reports · 2017-07-07

Review

685. The role for ketogenic diets in epilepsy and status epilepticus in adults.

Williams TJ, Cervenka MC · Clinical neurophysiology practice · 2017-07-01

Other

686. The Ketogenic Diet: Making a Comeback.

Walczyk T, Wick JY · The Consultant pharmacist : the journal of the American Society of Consultant Pharmacists · 2017-07-14

Preclinical / mechanistic

687. Various ketogenic diets can differently support brain resistance against experimentally evoked seizures and seizure-induced elemental anomalies of hippocampal formation.

Chwiej J, Patulska A, Skoczen A, Matusiak K, Janeczko K, Ciarach M, Simon R, Setkowicz Z · Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) · 2017-04-10

Preclinical / mechanistic

688. The ketogenic diet metabolite beta-hydroxybutyrate (β-HB) reduces incidence of seizure-like activity (SLA) in a Katp- and GABAb-dependent manner in a whole-animal Drosophila melanogaster model.

Li J, O'Leary EI, Tanner GR · Epilepsy research · 2017-04-05

Other

689. The Effect of Ketogenic Diet on Serum Selenium Levels in Patients with Intractable Epilepsy.

Arslan N, Kose E, Guzel O · Biological trace element research · 2016-11-21

Preclinical / mechanistic

690. The effect of ketogenic diet in an animal model of autism induced by prenatal exposure to valproic acid.

Castro K, Baronio D, Perry IS, Riesgo RDS, Gottfried C · Nutritional neuroscience · 2016-02-08

Observational human study

691. Ketogenic Diet for the Management of Epilepsy Associated with Tuberous Sclerosis Complex in Children.

Park S, Lee EJ, Eom S, Kang HC, Lee JS, Kim HD · Journal of epilepsy research · 2017-06-30

Observational human study

692. Ketogenic diet: Predictors of seizure control.

Agarwal N, Arkilo D, Farooq O, Gillogly C, Kavak KS, Weinstock A · SAGE open medicine · 2017-06-06

Other

693. Why should modified Atkins diet be encouraged for treating epilepsy in emerging countries?

Satte A, Kossoff EH, Belghiti M, Zerhouni A, Ouhabi H, Guerinech H, Mounach J · African health sciences · 2017-10-25

Other

694. Response to "A randomized controlled trial of the ketogenic diet in refractory childhood epilepsy".

Almomen M, Burton J · Acta neurologica Scandinavica · 2017-04-27

Review

695. Use of the Ketogenic Diet to Treat Intractable Epilepsy in Mitochondrial Disorders.

Paleologou E, Ismayilova N, Kinali M · Journal of clinical medicine · 2017-05-26

Other

696. An examination of biochemical parameters and their association with response to ketogenic dietary therapies.

Schoeler NE, Bell G, Yuen A, Kapelner AD, Heales SJR, Cross JH, Sisodiya S · Epilepsia · 2017-04-03

Randomized clinical trial

697. Long-term clinical outcomes and economic evaluation of the ketogenic diet versus care as usual in children and adolescents with intractable epilepsy.

Wijnen BFM, de Kinderen RJA, Lambrechts DAJE, Postulart D, Aldenkamp AP, Majoie MHJM, Evers SMAA · Epilepsy research · 2017-03-21

Review

698. Ketogenic diet and childhood neurological disorders other than epilepsy: an overview.

Verrotti A, Iapadre G, Pisano S, Coppola G · Expert review of neurotherapeutics · 2016-11-21

Randomized clinical trial

699. Ketogenic diet in the treatment of epilepsy in children under the age of 2 years: study protocol for a randomised controlled trial.

Titre-Johnson S, Schoeler N, Eltze C, Williams R, Vezyroglou K, McCullagh H, Freemantle N, Heales S, Kneen R, Marston L, Martland T, Nazareth I, Neal E, Lux A, Parker A, Agrawal S, Fallon P, Cross JH · Trials · 2017-04-26

Randomized clinical trial

700. Modified Atkins diet in adult with refractory epilepsy: A controlled randomized clinical trial.

Zare M, Okhovat AA, Esmaillzadeh A, Mehvari J, Najafi MR, Saadatnia M · Iranian journal of neurology · 2017-08-02

Other

701. The use of a formula-based ketogenic diet in children with refractory epilepsy.

Sampaio LPB, Takakura C, Manreza MLG · Arquivos de neuro-psiquiatria · 2016-09-07

Preclinical / mechanistic

702. Sex-Specific Life Course Changes in the Neuro-Metabolic Phenotype of Glut3 Null Heterozygous Mice: Ketogenic Diet Ameliorates Electroencephalographic Seizures and Improves Sociability.

Dai Y, Zhao Y, Tomi M, Shin BC, Thamotharan S, Mazarati A, Sankar R, Wang EA, Cepeda C, Levine MS, Zhang J, Frew A, Alger JR, Clark PM, Sondhi M, Kositamongkol S, Leibovitch L, Devaskar SU · Endocrinology · 2016-11-03

Observational human study

703. Modified Atkins diet is an effective treatment for children with Doose syndrome.

Wiemer-Kruel A, Haberlandt E, Hartmann H, Wohlrab G, Bast T · Epilepsia · 2017-02-23

Review

704. New insights into the mechanisms of the ketogenic diet.

Boison D · Current opinion in neurology · 2017-02-01

Other

705. Changes of thyroid hormonal status in patients receiving ketogenic diet due to intractable epilepsy.

Kose E, Guzel O, Demir K, Arslan N · Journal of pediatric endocrinology & metabolism : JPEM · 2016-07-14

Preclinical / mechanistic

706. Proconvulsant effects of the ketogenic diet in electroshock-induced seizures in mice.

Zarnowska I, Luszczki JJ, Zarnowski T, Wlaz P, Czuczwar SJ, Gasior M · Metabolic brain disease · 2016-09-20

Guideline / consensus

707. A Practical Approach to Ketogenic Diet in the Pediatric Intensive Care Unit for Super-Refractory Status Epilepticus.

Farias-Moeller R, Bartolini L, Pasupuleti A, Brittany Cines RD, Kao A, Carpenter JL · Neurocritical care · 2016-08-25

Observational human study

708. The efficacy of the modified Atkins diet in North Sea Progressive Myoclonus Epilepsy: an observational prospective open-label study.

van Egmond ME, Weijenberg A, van Rijn ME, Elting JW, Gelauff JM, Zutt R, Sival DA, Lambrechts RA, Tijssen MA, Brouwer OF, de Koning TJ · Orphanet journal of rare diseases · 2017-03-07

Randomized clinical trial

709. Phase I/II multicenter ketogenic diet study for adult superrefractory status epilepticus.

Cervenka MC, Hocker S, Koenig M, Bar B, Henry-Barron B, Kossoff EH, Hartman AL, Probasco JC, Benavides DR, Venkatesan A, Hagen EC, Dittrich D, Stern T, Radzik B, Depew M, Caserta FM, Nyquist P, Kaplan PW, Geocadin RG · Neurology · 2017-02-08

Preclinical / mechanistic

710. Antiseizure Effects of Ketogenic Diet on Seizures Induced with Pentylenetetrazole, 4-Aminopyridine and Strychnine in Wistar Rats.

Sanya EO, Soladoye AO, Desalu OO, Kolo PM, Olatunji LA, Olarinoye JK · Nigerian journal of physiological sciences : official publication of the Physiological Society of Nigeria · 2017-03-06

Observational human study

711. Efficacy of a ketogenic diet in resistant myoclono-astatic epilepsy: A French multicenter retrospective study.

Stenger E, Schaeffer M, Cances C, Motte J, Auvin S, Ville D, Maurey H, Nabbout R, de Saint-Martin A · Epilepsy research · 2017-02-20

Other

712. Decreased health care utilization and health care costs in the inpatient and emergency department setting following initiation of ketogenic diet in pediatric patients: The experience in Ontario, Canada.

Whiting S, Donner E, RamachandranNair R, Grabowski J, Jetté N, Duque DR · Epilepsy research · 2017-02-20

Clinical trial / intervention

713. Complications During Ketogenic Diet Initiation: Prevalence, Treatment, and Influence on Seizure Outcomes.

Lin A, Turner Z, Doerrer SC, Stanfield A, Kossoff EH · Pediatric neurology · 2017-01-16

Clinical trial / intervention

714. The efficacy of the ketogenic diet in infants and young children with refractory epilepsies using a formula-based powder.

Ashrafi MR, Hosseini SA, Zamani GR, Mohammadi M, Tavassoli A, Badv RS, Heidari M, Karimi P, Malamiri RA · Acta neurologica Belgica · 2016-12-07

Case report / case series

715. Combination of ketogenic diet and stiripentol for super-refractory status epilepticus: A case report.

Uchida Y, Kato D, Toyoda T, Oomura M, Ueki Y, Ohkita K, Matsukawa N · Journal of the neurological sciences · 2016-12-15

Case report / case series

716. Ketogenic diet therapy for epilepsy during pregnancy: A case series.

van der Louw EJ, Williams TJ, Henry-Barron BJ, Olieman JF, Duvekot JJ, Vermeulen MJ, Bannink N, Williams M, Neuteboom RF, Kossoff EH, Catsman-Berrevoets CE, Cervenka MC · Seizure · 2016-12-26

Observational human study

717. Use of the ketogenic diet in the neonatal intensive care unit-Safety and tolerability.

Thompson L, Fecske E, Salim M, Hall A · Epilepsia · 2017-01-12

Preclinical / mechanistic

718. GAPDH-mediated posttranscriptional regulations of sodium channel Scn1a and Scn3a genes under seizure and ketogenic diet conditions.

Lin GW, Lu P, Zeng T, Tang HL, Chen YH, Liu SJ, Gao MM, Zhao QH, Yi YH, Long YS · Neuropharmacology · 2016-11-02

Review

719. How does the ketogenic diet induce anti-seizure effects?

Rho JM · Neuroscience letters · 2015-07-26

Systematic review / meta-analysis

720. Ketogenic Diets in the Treatment of Epilepsy.

Elia M, Klepper J, Leiendecker B, Hartmann H · Current pharmaceutical design · 2017-06-20

Other

721. Changes in quality of life as a result of ketogenic diet therapy: A new approach to assessment with the potential for positive therapeutic effects.

Bruce S, Devlin A, Air L, Cook L · Epilepsy & behavior : E&B · 2016-12-27

Preclinical / mechanistic

722. Ketogenic diets improve behaviors associated with autism spectrum disorder in a sex-specific manner in the EL mouse.

Ruskin DN, Fortin JA, Bisnauth SN, Masino SA · Physiology & behavior · 2016-11-09

Other

723. The addition of ketone bodies alleviates mitochondrial dysfunction by restoring complex I assembly in a MELAS cellular model.

Frey S, Geffroy G, Desquiret-Dumas V, Gueguen N, Bris C, Belal S, Amati-Bonneau P, Chevrollier A, Barth M, Henrion D, Lenaers G, Bonneau D, Reynier P, Procaccio V · Biochimica et biophysica acta. Molecular basis of disease · 2016-11-01

Clinical trial / intervention

724. Control of seizures by ketogenic diet-induced modulation of metabolic pathways.

Clanton RM, Wu G, Akabani G, Aramayo R · Amino acids · 2016-09-28

Preclinical / mechanistic

725. Regulation of brain PPARgamma2 contributes to ketogenic diet anti-seizure efficacy.

Simeone TA, Matthews SA, Samson KK, Simeone KA · Experimental neurology · 2016-08-12

Clinical trial / intervention

726. To treat or not to treat drug-refractory epilepsy by the ketogenic diet? That is the question.

Ułamek-Kozioł M, Pluta R, Bogucka-Kocka A, Czuczwar SJ · Annals of agricultural and environmental medicine : AAEM · 2016-12-30

Review

727. The Ketogenic Diet: A Practical Guide for Pediatricians.

Luat AF, Coyle L, Kamat D · Pediatric annals · 2016-12-16

Observational human study

728. Pediatric patients on ketogenic diet undergoing general anesthesia-a medical record review.

Soysal E, Gries H, Wray C · Journal of clinical anesthesia · 2016-08-20

Observational human study

729. Is ketogenic diet treatment hepatotoxic for children with intractable epilepsy?

Arslan N, Guzel O, Kose E, Yılmaz U, Kuyum P, Aksoy B, Çalık T · Seizure · 2016-11-13

Observational human study

730. Therapeutic effects of the ketogenic diet in children with Lennox-Gastaut syndrome.

Zhang Y, Wang Y, Zhou Y, Zhang L, Yu L, Zhou S · Epilepsy research · 2016-11-09

Preclinical / mechanistic

731. Ketone ester supplementation attenuates seizure activity, and improves behavior and hippocampal synaptic plasticity in an Angelman syndrome mouse model.

Ciarlone SL, Grieco JC, D'Agostino DP, Weeber EJ · Neurobiology of disease · 2016-08-18

Preclinical / mechanistic

732. Long-Term Effects of Ketogenic Diet on Subsequent Seizure-Induced Brain Injury During Early Adulthood: Relationship of Seizure Thresholds to Zinc Transporter-Related Gene Expressions.

Tian T, Li LL, Zhang SQ, Ni H · Biological trace element research · 2016-05-05

Clinical trial / intervention

733. The effects of classic ketogenic diet on serum lipid profile in children with refractory seizures.

Zamani GR, Mohammadi M, Ashrafi MR, Karimi P, Mahmoudi M, Badv RS, Tavassoli AR, Azizi Malamiri R · Acta neurologica Belgica · 2016-01-20

Review

734. How effective is the ketogenic diet for electrical status epilepticus of sleep?

Kelley SA, Kossoff EH · Epilepsy research · 2016-09-23

Randomized clinical trial

735. Evaluation of a simplified modified Atkins diet for use by parents with low levels of literacy in children with refractory epilepsy: A randomized controlled trial.

Sharma S, Goel S, Jain P, Agarwala A, Aneja S · Epilepsy research · 2016-09-01

Case report / case series

736. SLC6A1 Mutation and Ketogenic Diet in Epilepsy With Myoclonic-Atonic Seizures.

Palmer S, Towne MC, Pearl PL, Pelletier RC, Genetti CA, Shi J, Beggs AH, Agrawal PB, Brownstein CA · Pediatric neurology · 2016-07-28

Observational human study

737. A prospective study on changes in blood levels of cholecystokinin-8 and leptin in patients with refractory epilepsy treated with the ketogenic diet.

Lambrechts DA, Brandt-Wouters E, Verschuure P, Vles HS, Majoie MJ · Epilepsy research · 2016-08-16

Observational human study

738. Use of modified Atkins diet in glucose transporter type 1 deficiency syndrome.

Amalou S, Gras D, Ilea A, Greneche MO, Francois L, Bellavoine V, Delanoe C, Auvin S · Developmental medicine and child neurology · 2016-06-08

Other

739. Efficacy and tolerability of the modified Atkins diet in young children with refractory epilepsy: Indian experience.

Mehta R, Goel S, Sharma S, Jain P, Mukherjee SB, Aneja S · Annals of Indian Academy of Neurology · 2016-12-21

Review

740. Ketogenic diet for epilepsy treatment.

Sampaio LP · Arquivos de neuro-psiquiatria · 2016-05-04

Case report / case series

741. Ketogenic diet - A novel treatment for early epileptic encephalopathy due to PIGA deficiency.

Joshi C, Kolbe DL, Mansilla MA, Mason S, Smith RJ, Campbell CA · Brain & development · 2016-04-25

Observational human study

742. Does ketogenic diet have any negative effect on cardiac systolic and diastolic functions in children with intractable epilepsy?: One-year follow-up results.

Ozdemir R, Kucuk M, Guzel O, Karadeniz C, Yilmaz U, Mese T · Brain & development · 2016-04-05

Review

743. MED23-associated refractory epilepsy successfully treated with the ketogenic diet.

Lionel AC, Monfared N, Scherer SW, Marshall CR, Mercimek-Mahmutoglu S · American journal of medical genetics. Part A · 2016-06-17

Preclinical / mechanistic

744. Ketogenic diet treatment increases longevity in Kcna1-null mice, a model of sudden unexpected death in epilepsy.

Simeone KA, Matthews SA, Rho JM, Simeone TA · Epilepsia · 2016-06-27

Other

745. Outcome of ketogenic diets in GLUT1 deficiency syndrome in Japan: A nationwide survey.

Fujii T, Ito Y, Takahashi S, Shimono K, Natsume J, Yanagihara K, Oguni H · Brain & development · 2016-02-26

Preclinical / mechanistic

746. Ketogenic diet prevents neuronal firing increase within the substantia nigra during pentylenetetrazole-induced seizure in rats.

Viggiano A, Stoddard M, Pisano S, Operto FF, Iovane V, Monda M, Coppola G · Brain research bulletin · 2016-07-02

Clinical trial / intervention

747. Valproate effect on ketosis in children under ketogenic diet.

Spilioti M, Pavlou E, Gogou M, Katsanika I, Papadopoulou-Alataki E, Grafakou O, Gkampeta A, Dinopoulos A, Evangeliou A · European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society · 2016-04-13

Randomized clinical trial

748. Ketogenic Diet, but Not Polyunsaturated Fatty Acid Diet, Reduces Spontaneous Seizures in Juvenile Rats with Kainic Acid-induced Epilepsy.

Dustin SM, Stafstrom CE · Journal of epilepsy research · 2016-06-30

Observational human study

749. The Impact of 3:1 Ketogenic Diet on Cardiac Repolarization Changes in Children with Refractory Seizures: A Prospective Follow-Up Study.

Özdemir R, Güzel O, Küçük M, Karadeniz C, Yılmaz Ü, Calik T, Meşe T · Neuropediatrics · 2016-04-04

Review

750. Ketogenic dietary therapies in adults with epilepsy: a practical guide.

Schoeler NE, Cross JH · Practical neurology · 2016-02-23

Case report / case series

751. Usefulness of ketogenic diet in a girl with migrating partial seizures in infancy.

Mori T, Imai K, Oboshi T, Fujiwara Y, Takeshita S, Saitsu H, Matsumoto N, Takahashi Y, Inoue Y · Brain & development · 2016-01-11

Other

752. [Ketogenic diet as a therapeutic option in refractory epilepsy].

Gorria Redondo N, Angulo García ML, Montesclaros Hortigüela Saeta M, Conejo Moreno D · Anales de pediatria (Barcelona, Spain : 2003) · 2015-12-03

Systematic review / meta-analysis

753. [Effectiveness of a ketogenic diet in children with refractory epilepsy: a systematic review].

Araya-Quintanilla F, Celis-Rosati A, Rodriguez-Leiva C, Silva-Navarro C, Silva-Pinto Y, Toro-Jeria B · Revista de neurologia · 2016-05-06

Review

754. Mechanisms of Action of Antiseizure Drugs and the Ketogenic Diet.

Rogawski MA, Löscher W, Rho JM · Cold Spring Harbor perspectives in medicine · 2016-05-02

Other

755. The effects of ketogenic diet on the Th17/Treg cells imbalance in patients with intractable childhood epilepsy.

Ni FF, Li CR, Liao JX, Wang GB, Lin SF, Xia Y, Wen JL · Seizure · 2016-03-22

Guideline / consensus

756. [National consensus on the modified Atkins diet].

Vaccarezza M, Agustinho A, Alberti MJ, Argumedo L, Armeno M, Blanco V, Bouquet C, Cabrera A, Caraballo R, Caramuta L, Cresta A, de Grandis ES, DeMartini MG, Diez C, Diz M, Dlugoszewski C, Escobal N, Ferrero H, Galicchio S, Gambarini V, Gamboni B, Gonzalez L, Guisande S, Hassan A, Matarrese P, Mestre G, Pesce L, Rios V, Semprino M, Sosa P, Toma M, Viollaz R, Panico L · Revista de neurologia · 2016-04-12

Other

757. ERRATUM: Ketogenic Diet for Children with Epilepsy: A Practical Meal Plan in a Hospital.

Lee E, Kang HC, Kim HD · Clinical nutrition research · 2016-04-30

Other

758. The effect of olive oil-based ketogenic diet on serum lipid levels in epileptic children.

Güzel O, Yılmaz U, Uysal U, Arslan N · Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2015-12-23

Preclinical / mechanistic

759. Effectiveness of ketogenic diet in pentylenetetrazol-induced and kindling rats as well as its potential mechanisms.

Wang S, Ding Y, Ding XY, Liu ZR, Shen CH, Jin B, Guo Y, Wang S, Ding MP · Neuroscience letters · 2016-01-02

Systematic review / meta-analysis

760. Ketogenic diet and other dietary treatments for epilepsy.

Martin K, Jackson CF, Levy RG, Cooper PN · The Cochrane database of systematic reviews · 2016-02-09

Other

761. [Ketogenic diet also for adult epileptics?].

Füessl HS, Stiefelhagen P · MMW Fortschritte der Medizin · 2016-03-11

Other

762. Effectiveness of Medium Chain Triglyceride Ketogenic Diet in Thai Children with Intractable Epilepsy.

Chomtho K, Suteerojntrakool O, Chomtho S · Journal of the Medical Association of Thailand = Chotmaihet thangphaet · 2016-06-03

Guideline / consensus

763. Recommendations for the clinical management of children with refractory epilepsy receiving the ketogenic diet.

Alberti MJ, Agustinho A, Argumedo L, Armeno M, Blanco V, Bouquet C, Cabrera A, Caraballo R, Caramuta L, Cresta A, de Grandis ES, De Martini MG, Diez C, Dlugoszewski C, Escobal N, Ferrero H, Galicchio S, Gambarini V, Gamboni B, Guisande S, Hassan A, Matarrese P, Mestre G, Pesce L, Ríos V, Sosa P, Vaccarezza M, Viollaz R, Panico L · Archivos argentinos de pediatria · 2015-12-23

Other

764. A fatty acid in the MCT ketogenic diet for epilepsy treatment blocks AMPA receptors.

Rogawski MA · Brain : a journal of neurology · 2016-02-26

Observational human study

765. Limited efficacy of the ketogenic diet in the treatment of highly refractory epileptic spasms.

Hussain SA, Shin JH, Shih EJ, Murata KK, Sewak S, Kezele ME, Sankar R, Matsumoto JH · Seizure · 2016-01-09

Other

766. Six-month efficacy of the Ketogenic diet is predicted after 3 months and is unrelated to clinical variables.

Wu YJ, Zhang LM, Chai YM, Wang J, Yu LF, Li WH, Zhou YF, Zhou SZ · Epilepsy & behavior : E&B · 2016-01-16

Observational human study

767. Ketogenic diet effects on neurobehavioral development of children with intractable epilepsy: A prospective study.

Zhu D, Wang M, Wang J, Yuan J, Niu G, Zhang G, Sun L, Xiong H, Xie M, Zhao Y · Epilepsy & behavior : E&B · 2016-01-13

Randomized clinical trial

768. Effects of a ketogenic diet on ADHD-like behavior in dogs with idiopathic epilepsy.

Packer RM, Law TH, Davies E, Zanghi B, Pan Y, Volk HA · Epilepsy & behavior : E&B · 2016-01-07

Preclinical / mechanistic

769. Ketogenic diet change cPLA2/clusterin and autophagy related gene expression and correlate with cognitive deficits and hippocampal MFs sprouting following neonatal seizures.

Ni H, Zhao DJ, Tian T · Epilepsy research · 2015-12-03

Preclinical / mechanistic

770. Is the interaction between fatty acids and tryptophan responsible for the efficacy of a ketogenic diet in epilepsy? The new hypothesis of action.

Maciejak P, Szyndler J, Turzyńska D, Sobolewska A, Kołosowska K, Krząścik P, Płaźnik A · Neuroscience · 2015-11-19

Observational human study

771. Ketogenic Diet Decreases Emergency Room Visits and Hospitalizations Related to Epilepsy.

Kayyali HR, Luniova A, Abdelmoity A · Epilepsy research and treatment · 2016-09-26

Randomized clinical trial

772. [Autism spectrum disorder and epilepsy: the role of ketogenic diet].

Garcia-Penas JJ · Revista de neurologia · 2016-03-01

Clinical trial / intervention

773. Ketogenic Diet for Children with Epilepsy: A Practical Meal Plan in a Hospital.

Lee E, Kang HC, Kim HD · Clinical nutrition research · 2016-01-29

Case report / case series

774. Hepatic Dysfunction as a Complication of Combined Valproate and Ketogenic Diet.

Stevens CE, Turner Z, Kossoff EH · Pediatric neurology · 2015-10-24

Randomized clinical trial

775. An economic evaluation of the ketogenic diet versus care as usual in children and adolescents with intractable epilepsy: An interim analysis.

de Kinderen RJ, Lambrechts DA, Wijnen BF, Postulart D, Aldenkamp AP, Majoie MH, Evers SM · Epilepsia · 2015-11-29

Observational human study

776. Retrospective evaluation of low long-term efficacy of antiepileptic drugs and ketogenic diet in 39 patients with CDKL5-related epilepsy.

Müller A, Helbig I, Jansen C, Bast T, Guerrini R, Jähn J, Muhle H, Auvin S, Korenke GC, Philip S, Keimer R, Striano P, Wolf NI, Püst B, Thiels Ch, Fogarasi A, Waltz S, Kurlemann G, Kovacevic-Preradovic T, Ceulemans B, Schmitt B, Philippi H, Tarquinio D, Buerki S, von Stülpnagel C, Kluger G · European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society · 2015-09-10

Other

777. Diet and identity: being a good parent in the face of contradictions presented by the ketogenic diet.

Webster M, Gabe J · Sociology of health & illness · 2015-09-18

Randomized clinical trial

778. Efficacy of the classic ketogenic and the modified Atkins diets in refractory childhood epilepsy.

Kim JA, Yoon JR, Lee EJ, Lee JS, Kim JT, Kim HD, Kang HC · Epilepsia · 2015-12-10

Case report / case series

779. The ketogenic diet in two paediatric patients with refractory myoclonic status epilepticus.

Caraballo RH, Valenzuela GR, Armeno M, Fortini S, Mestre G, Cresta A · Epileptic disorders : international epilepsy journal with videotape · 2015-11-27

Other

780. Variants in KCNJ11 and BAD do not predict response to ketogenic dietary therapies for epilepsy.

Schoeler NE, Leu C, White J, Plagnol V, Ellard S, Matarin M, Yellen G, Thiele EA, Mackay M, McMahon JM, Scheffer IE, Sander JW, Cross JH, Sisodiya SM · Epilepsy research · 2015-10-24

Clinical trial / intervention

781. A prospective study of the modified Atkins diet for adults with idiopathic generalized epilepsy.

Kverneland M, Selmer KK, Nakken KO, Iversen PO, Taubøll E · Epilepsy & behavior : E&B · 2015-11-14

Preclinical / mechanistic

782. Ketogenic diet prevents epileptogenesis and disease progression in adult mice and rats.

Lusardi TA, Akula KK, Coffman SQ, Ruskin DN, Masino SA, Boison D · Neuropharmacology · 2015-08-06

Case report / case series

783. Ketogenic Diet as a Therapeutic Option in Super-refractory Status Epilepticus.

Fung EL, Chang SK, Yam KK, Yau PY · Pediatrics and neonatology · 2015-05-14

Observational human study

784. Concomitant lamotrigine use is associated with decreased efficacy of the ketogenic diet in childhood refractory epilepsy.

van der Louw EJ, Desadien R, Vehmeijer FO, van der Sijs H, Catsman-Berrevoets CE, Neuteboom RF · Seizure · 2015-09-21

Other

785. Efficacy of the Ketogenic Diet for the Treatment of Refractory Childhood Epilepsy: Cerebrospinal Fluid Neurotransmitters and Amino Acid Levels.

Sariego-Jamardo A, García-Cazorla A, Artuch R, Castejón E, García-Arenas D, Molero-Luis M, Ormazábal A, Sanmartí FX · Pediatric neurology · 2015-08-08

Observational human study

786. Can we predict efficacy of the ketogenic diet in children with refractory epilepsy?

Vehmeijer FO, van der Louw EJ, Arts WF, Catsman-Berrevoets CE, Neuteboom RF · European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society · 2015-07-09

Other

787. Use of the ketogenic diet in an adult with myoclonic status epilepticus.

Cash C · Clinical nutrition ESPEN · 2015-08-28

Other

788. CSF Amino Acids, Pterins and Mechanism of the Ketogenic Diet.

Millichap JG · Pediatric neurology briefs · 2016-03-03

Observational human study

789. The ketogenic diet in infants--Advantages of early use.

Dressler A, Trimmel-Schwahofer P, Reithofer E, Gröppel G, Mühlebner A, Samueli S, Grabner V, Abraham K, Benninger F, Feucht M · Epilepsy research · 2015-07-09

Observational human study

790. The MCT-ketogenic diet as a treatment option in refractory childhood epilepsy: A prospective study with 2-year follow-up.

Lambrechts DA, de Kinderen RJ, Vles HS, de Louw AJ, Aldenkamp AP, Majoie MJ · Epilepsy & behavior : E&B · 2015-08-24

Other

791. The Effects of Ketogenic Diet on Seizures, Cognitive Functions, and Other Neurological Disorders in Classical Phenotype of Glucose Transporter 1 Deficiency Syndrome.

Gumus H, Bayram AK, Kardas F, Canpolat M, Çağlayan AO, Kumandas S, Kendirci M, Per H · Neuropediatrics · 2015-08-12

Observational human study

792. The Short-Term Effect of Ketogenic Diet on Carotid Intima-Media Thickness and Elastic Properties of the Carotid Artery and the Aorta in Epileptic Children.

Doksöz Ö, Güzel O, Yılmaz Ü, İşgüder R, Çeleğen K, Meşe T, Uysal U · Journal of child neurology · 2015-04-08

Preclinical / mechanistic

793. Neurobehavioral Deficits in a Rat Model of Recurrent Neonatal Seizures Are Prevented by a Ketogenic Diet and Correlate with Hippocampal Zinc/Lipid Transporter Signals.

Tian T, Ni H, Sun BL · Biological trace element research · 2015-03-17

Case report / case series

794. Ketogenic diet in a patient with congenital hyperinsulinism: a novel approach to prevent brain damage.

Maiorana A, Manganozzi L, Barbetti F, Bernabei S, Gallo G, Cusmai R, Caviglia S, Dionisi-Vici C · Orphanet journal of rare diseases · 2015-09-24

Other

795. First Application of Ketogenic Diet on a Child With Intractable Epilepsy in Ghana.

Cao D, Badoe E, Zhu Y, Zhao X, Hu Y, Liao J · Child neurology open · 2015-09-21

Preclinical / mechanistic

796. Ketone Bodies Mediate Antiseizure Effects.

Krueger JM, Nordli DR · Pediatric neurology briefs · 2016-03-03

Observational human study

797. The Short-Term Effects of Ketogenic Diet on Cardiac Ventricular Functions in Epileptic Children.

Doksöz Ö, Çeleğen K, Güzel O, Yılmaz Ü, Uysal U, İşgüder R, Çeleğen M, Meşe T · Pediatric neurology · 2015-06-18

Review

798. Predictors of Ketogenic Diet Efficacy in Children Based on the Electroencephalogram (EEG).

Walker I, Said RR · Journal of child neurology · 2014-11-20

Preclinical / mechanistic

799. Anticonvulsant properties of an oral ketone ester in a pentylenetetrazole-model of seizure.

Viggiano A, Pilla R, Arnold P, Monda M, D'Agostino D, Coppola G · Brain research · 2015-05-27

Preclinical / mechanistic

800. The influence of the ketogenic diet on the elemental and biochemical compositions of the hippocampal formation.

Chwiej J, Skoczen A, Matusiak K, Janeczko K, Patulska A, Sandt C, Simon R, Ciarach M, Setkowicz Z · Epilepsy & behavior : E&B · 2015-05-16

Case report / case series

801. SCN2A mutation in a Chinese boy with infantile spasm - response to Modified Atkins Diet.

Wong VC, Fung CW, Kwong AK · Brain & development · 2014-11-07

Systematic review / meta-analysis

802. Epilepsy: behavioural, psychological, and ketogenic diet treatments.

Cross H · BMJ clinical evidence · 2015-07-10

Review

803. Ketogenic diets in patients with inherited metabolic disorders.

Scholl-Bürgi S, Höller A, Pichler K, Michel M, Haberlandt E, Karall D · Journal of inherited metabolic disease · 2015-06-25

Observational human study

804. The ketogenic diet can be used successfully in combination with corticosteroids for epileptic encephalopathies.

Ville D, Chiron C, Laschet J, Dulac O · Epilepsy & behavior : E&B · 2015-06-08

Observational human study

805. Ketogenic diet in patients with epileptic encephalopathy with electrical status epilepticus during slow sleep.

Reyes G, Flesler S, Armeno M, Fortini S, Ariela A, Cresta A, Mestre G, Caraballo RH · Epilepsy research · 2015-04-09

Preclinical / mechanistic

806. Rapid adaptation of rat brain and liver metabolism to a ketogenic diet: an integrated study using (1)H- and (13)C-NMR spectroscopy.

Roy M, Beauvieux MC, Naulin J, El Hamrani D, Gallis JL, Cunnane SC, Bouzier-Sore AK · Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2015-03-18

Case report / case series

807. Cardiopulmonary bypass considerations for pediatric patients on the ketogenic diet.

Melchior RW, Dreher M, Ramsey E, Savoca M, Rosenthal T · Perfusion · 2014-11-07

Review

808. The ketogenic diet in pharmacoresistant childhood epilepsy.

Winesett SP, Bessone SK, Kossoff EH · Expert review of neurotherapeutics · 2015-05-20

Other

809. Protein-losing enteropathy in a patient on ketogenic diet for limbic encephalitis--treatment effect or underlying pathology?

Mordaunt DA · Pediatric neurology · 2015-02-23

Case report / case series

810. Epilepsy of infancy with migrating focal seizures: three patients treated with the ketogenic diet.

Caraballo R, Noli D, Cachia P · Epileptic disorders : international epilepsy journal with videotape · 2015-04-22

Other

811. How do you keto? Survey of North American pediatric ketogenic diet centers.

Jung DE, Joshi SM, Berg AT · Journal of child neurology · 2014-08-19

Other

812. Substantial and sustained seizure reduction with ketogenic diet in a patient with Ohtahara syndrome.

Sivaraju A, Nussbaum I, Cardoza CS, Mattson RH · Epilepsy & behavior case reports · 2015-05-15

Preclinical / mechanistic

813. Effects of a ketogenic diet on hippocampal plasticity in freely moving juvenile rats.

Blaise JH, Ruskin DN, Koranda JL, Masino SA · Physiological reports · 2015-05-27

Other

814. Refractory status epilepticus from NMDA receptor encephalitis successfully treated with an adjunctive ketogenic diet.

Amer S, Shah P, Kommineni V · Annals of Indian Academy of Neurology · 2015-05-29

Case report / case series

815. Intravenous ketogenic diet therapy for treatment of the acute stage of super-refractory status epilepticus in a pediatric patient.

Lin JJ, Lin KL, Chan OW, Hsia SH, Wang HS, CHEESE Study Group · Pediatric neurology · 2014-12-31

Observational human study

816. Ten-year single-center experience of the ketogenic diet: factors influencing efficacy, tolerability, and compliance.

Wibisono C, Rowe N, Beavis E, Kepreotes H, Mackie FE, Lawson JA, Cardamone M · The Journal of pediatrics · 2015-01-30

Review

817. The Keilah Foundation: making the ketogenic diet viable for children in Africa.

Megaw K, Wilmshurst JM · Epilepsia · 2014-10-13

Observational human study

818. Use of the modified Atkins diet in Lennox Gastaut syndrome.

Sharma S, Jain P, Gulati S, Sankhyan N, Agarwala A · Journal of child neurology · 2014-03-20

Clinical trial / intervention

819. Modified Atkins diet may reduce serum concentrations of antiepileptic drugs.

Kverneland M, Taubøll E, Selmer KK, Iversen PO, Nakken KO · Acta neurologica Scandinavica · 2014-10-14

Other

820. Cost-effectiveness of the ketogenic diet and vagus nerve stimulation for the treatment of children with intractable epilepsy.

de Kinderen RJ, Postulart D, Aldenkamp AP, Evers SM, Lambrechts DA, Louw AJ, Majoie MH, Grutters JP · Epilepsy research · 2014-12-13

Observational human study

821. Exploring the relationship between preferences for high fat foods and efficacy of the ketogenic and modified Atkins diets among children with seizure disorders.

Amari A, Turner Z, Rubenstein JE, Miller JR, Kossoff EH · Seizure · 2014-11-08

Preclinical / mechanistic

822. Effects of ketogenic diets on the occurrence of pilocarpine-induced status epilepticus of rats.

Gama IR, Trindade-Filho EM, Oliveira SL, Bueno NB, Melo IT, Cabral-Junior CR, Barros EM, Galvão JA, Pereira WS, Ferreira RC, Domingos BR, da Rocha Ataide T · Metabolic brain disease · 2014-07-09

Case report / case series

823. The ketogenic diet as broad-spectrum treatment for super-refractory pediatric status epilepticus: challenges in implementation in the pediatric and neonatal intensive care units.

Cobo NH, Sankar R, Murata KK, Sewak SL, Kezele MA, Matsumoto JH · Journal of child neurology · 2014-01-23

Other

824. [Experience of using ketogenic diet in a patient with glucose transporter 1 deficiency syndrome (a case report)].

Lukyanova EG, Ayvazyan SO, Osipova KV, Pyreva EA, Sorvacheva TN · Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova · 2015-09-11

Systematic review / meta-analysis

825. Efficacy of and patient compliance with a ketogenic diet in adults with intractable epilepsy: a meta-analysis.

Ye F, Li XJ, Jiang WL, Sun HB, Liu J · Journal of clinical neurology (Seoul, Korea) · 2015-01-02

Observational human study

826. Efficacy and tolerability of the ketogenic diet in Dravet syndrome - Comparison with various standard antiepileptic drug regimen.

Dressler A, Trimmel-Schwahofer P, Reithofer E, Mühlebner A, Gröppel G, Reiter-Fink E, Benninger F, Grassl R, Feucht M · Epilepsy research · 2014-10-28

Observational human study

827. Effectiveness of the ketogenic diet used to treat resistant childhood epilepsy in Scandinavia.

Hallböök T, Sjölander A, Åmark P, Miranda M, Bjurulf B, Dahlin M · European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society · 2014-10-06

Preclinical / mechanistic

828. Seizure control by derivatives of medium chain fatty acids associated with the ketogenic diet show novel branching-point structure for enhanced potency.

Chang P, Zuckermann AM, Williams S, Close AJ, Cano-Jaimez M, McEvoy JP, Spencer J, Walker MC, Williams RS · The Journal of pharmacology and experimental therapeutics · 2014-10-17

Clinical trial / intervention

829. Dietary and medication adjustments to improve seizure control in patients treated with the ketogenic diet.

Selter JH, Turner Z, Doerrer SC, Kossoff EH · Journal of child neurology · 2014-05-22

Observational human study

830. Ketogenic diet therapy can improve ACTH-resistant West syndrome in Japan.

Hirano Y, Oguni H, Shiota M, Nishikawa A, Osawa M · Brain & development · 2014-02-18

Review

831. Monocarboxylate transporters in temporal lobe epilepsy: roles of lactate and ketogenic diet.

Lauritzen F, Eid T, Bergersen LH · Brain structure & function · 2013-11-19

Other

832. Ketogenic Diet Provides Neuroprotective Effects against Ischemic Stroke Neuronal Damages.

Shaafi S, Mahmoudi J, Pashapour A, Farhoudi M, Sadigh-Eteghad S, Akbari H · Advanced pharmaceutical bulletin · 2014-12-31

Review

833. Neurobiochemical mechanisms of a ketogenic diet in refractory epilepsy.

Lima PA, Sampaio LP, Damasceno NR · Clinics (Sao Paulo, Brazil) · 2014-02-04

Observational human study

834. Ketogenic diet in pediatric patients with refractory focal status epilepticus.

Caraballo RH, Flesler S, Armeno M, Fortini S, Agustinho A, Mestre G, Cresta A, Buompadre MC, Escobal N · Epilepsy research · 2014-10-13

Case report / case series

835. Cognitive outcomes in febrile infection-related epilepsy syndrome treated with the ketogenic diet.

Singh RK, Joshi SM, Potter DM, Leber SM, Carlson MD, Shellhaas RA · Pediatrics · 2014-10-22

Preclinical / mechanistic

836. Ketogenic diet sensitizes glucose control of hippocampal excitability.

Kawamura M, Ruskin DN, Geiger JD, Boison D, Masino SA · Journal of lipid research · 2014-08-28

Observational human study

837. Linear growth of children on a ketogenic diet: does the protein-to-energy ratio matter?

Nation J, Humphrey M, MacKay M, Boneh A · Journal of child neurology · 2013-12-05

Other

838. Assessing parents' attitudes towards ketogenic dietary therapies.

Schoeler NE, MacDonald L, Champion H, Cross JH, Sander JW, Sisodiya SM, Horne R · Epilepsy & behavior : E&B · 2014-08-19

Observational human study

839. Ketogenic diet in patients with Lennox-Gastaut syndrome.

Caraballo RH, Fortini S, Fresler S, Armeno M, Ariela A, Cresta A, Mestre G, Escobal N · Seizure · 2014-06-19

Case report / case series

840. Ketogenic diet therapy is effective in encephalitis with refractory seizures.

Matsuzono K, Kurata T, Deguchi S, Yamashita T, Deguchi K, Abe K · Neurological research · 2014-04-16

Review

841. Nonpharmacologic care for patients with Lennox-Gastaut syndrome: ketogenic diets and vagus nerve stimulation.

Kossoff EH, Shields WD · Epilepsia · 2013-12-27

Case report / case series

842. Management of symptomatic cholelithiasis while on ketogenic diet: a case report.

Desai AA, Thompson LM, Abdelmoity AT, Kayyali H, St Peter SD · Pediatric neurology · 2014-05-21

Guideline / consensus

843. [National consensus on the ketogenic diet].

Armeno M, Caraballo R, Vaccarezza M, Alberti MJ, Ríos V, Galicchio S, de Grandis ES, Mestre G, Escobal N, Matarrese P, Viollaz R, Agostinho A, Díez C, Cresta A, Cabrera A, Blanco V, Ferrero H, Gambarini V, Sosa P, Bouquet C, Caramuta L, Guisande S, Gamboni B, Hassan A, Pesce L, Argumedo L, Dlugoszewski C, DeMartini MG, Panico L · Revista de neurologia · 2014-08-27

Preclinical / mechanistic

844. Glucose reduces the anticonvulsant effects of the ketogenic diet in EL mice.

Mantis JG, Meidenbauer JJ, Zimick NC, Centeno NA, Seyfried TN · Epilepsy research · 2014-06-02

Other

845. Ketogenic diet in children with intractable epilepsy: what about resting energy expenditure and growth?

Bertoli S, Battezzati A, Tagliabue A · Developmental medicine and child neurology · 2014-05-15

Other

846. Long-term impact of the ketogenic diet on growth and resting energy expenditure in children with intractable epilepsy.

Groleau V, Schall JI, Stallings VA, Bergqvist CA · Developmental medicine and child neurology · 2014-04-20

Review

847. Ketone body therapy: from the ketogenic diet to the oral administration of ketone ester.

Hashim SA, VanItallie TB · Journal of lipid research · 2014-03-05

Other

848. Re: the ketogenic diet for the treatment of pediatric status epilepticus.

Fung LW · Pediatric neurology · 2014-03-25

Other

849. Is ketogenic diet truly effective in mitochondrial epilepsy?

Finsterer J, Kothari S · Pediatric neurology · 2014-05-14

Case report / case series

850. The ketogenic diet for the treatment of myoclonic astatic epilepsy in a child with type 1 diabetes mellitus.

Aylward NM, Shah N, Sellers EA · Canadian journal of diabetes · 2014-07-09

Other

851. Treatment of refractory epilepsy with the modified Atkins diet.

Vaccarezza MM, Toma MV, Ramos Guevara JD, Diez CG, Agosta GE · Archivos argentinos de pediatria · 2013-03-27

Other

852. Epilepsy Treatment Simplified through Mobile Ketogenic Diet Planning.

Li H, Jauregui JL, Fenton C, Chee CM, Bergqvist AGC · Journal of mobile technology in medicine · 2017-08-11

Review

853. The ketogenic diet and other dietary treatments for refractory epilepsy in children.

Sharma S, Jain P · Annals of Indian Academy of Neurology · 2014-03-26

Clinical trial / intervention

854. The ketogenic and atkins diets effect on intractable epilepsy: a comparison.

Ghazavi A, Tonekaboni SH, Karimzadeh P, Nikibakhsh AA, Khajeh A, Fayyazi A · Iranian journal of child neurology · 2013-08-11

Other

855. Ketogenic diet for high partial pressure oxygen diving.

Valadao JM, Vigilante JA, DiGeorge NW, O'Connor SE, Bear A, Kenyon J, Annis H, Dituri J, Dituri AE, Whelan HT · Undersea & hyperbaric medicine : journal of the Undersea and Hyperbaric Medical Society, Inc · 2014-08-12

Other

856. Effects of ketogenic diet on vascular function.

Kapetanakis M, Liuba P, Odermarsky M, Lundgren J, Hallböök T · European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society · 2014-03-25

Preclinical / mechanistic

857. Ketogenic diet alters dopaminergic activity in the mouse cortex.

Church WH, Adams RE, Wyss LS · Neuroscience letters · 2014-04-24

Case report / case series

858. Long-term effects of a ketogenic diet on body composition and bone mineralization in GLUT-1 deficiency syndrome: a case series.

Bertoli S, Trentani C, Ferraris C, De Giorgis V, Veggiotti P, Tagliabue A · Nutrition (Burbank, Los Angeles County, Calif.) · 2014-01-29

Observational human study

859. Can an early 24-hour EEG predict the response to the ketogenic diet? A prospective study in 34 children and adults with refractory epilepsy treated with the ketogenic diet.

Ebus SC, Lambrechts DA, Herraets IJ, Majoie MJ, de Louw AJ, Boon PJ, Aldenkamp AP, Arends JB · Seizure · 2014-04-02

Other

860. Ketogenic diet in adolescents and adults with epilepsy.

Nei M, Ngo L, Sirven JI, Sperling MR · Seizure · 2014-03-12

Observational human study

861. [Therapeutic effect of ketogenic diet for refractory epilepsy in children: a prospective observational study].

Zhu DN, Xie MM, Wang JH, Wang J, Ma DY, Sun L, Li LC, Wang MM · Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2014-05-27

Preclinical / mechanistic

862. In vivo ketogenic diet treatment attenuates pathologic sharp waves and high frequency oscillations in in vitro hippocampal slices from epileptic Kv 1.1α knockout mice.

Simeone TA, Samson KK, Matthews SA, Simeone KA · Epilepsia · 2014-04-04

Observational human study

863. Early efficacy of the ketogenic diet is not affected by initial body mass index percentile.

Shull S, Diaz-Medina G, Wong-Kisiel L, Nickels K, Eckert S, Wirrell E · Pediatric neurology · 2014-01-07

Review

864. Neuroactive peptides as putative mediators of antiepileptic ketogenic diets.

Giordano C, Marchiò M, Timofeeva E, Biagini G · Frontiers in neurology · 2014-04-29

Randomized clinical trial

865. Risk of seizure recurrence after achieving initial seizure freedom on the ketogenic diet.

Taub KS, Kessler SK, Bergqvist AG · Epilepsia · 2014-03-27

Other

866. Dispersion durations of P-wave and QT interval in children treated with a ketogenic diet.

Doksöz Ö, Güzel O, Yılmaz Ü, Işgüder R, Çeleğen K, Meşe T · Pediatric neurology · 2013-12-10

Other

867. The impact of the ketogenic diet on arterial morphology and endothelial function in children and young adults with epilepsy: a case-control study.

Coppola G, Natale F, Torino A, Capasso R, D'Aniello A, Pironti E, Santoro E, Calabrò R, Verrotti A · Seizure · 2013-12-12

Other

868. Occurrence of GLUT1 deficiency syndrome in patients treated with ketogenic diet.

Ramm-Pettersen A, Nakken KO, Haavardsholm KC, Selmer KK · Epilepsy & behavior : E&B · 2014-02-06

Observational human study

869. Ketogenic diet efficacy in the treatment of intractable epileptic spasms.

Kayyali HR, Gustafson M, Myers T, Thompson L, Williams M, Abdelmoity A · Pediatric neurology · 2013-12-04

Observational human study

870. [The use of the ketogenic diet as treatment for refractory epilepsy in the paediatric age].

Pablos-Sánchez T, Oliveros-Leal L, Núñez-Enamorado N, Camacho-Salas A, Moreno-Villares JM, Simón-De las Heras R · Revista de neurologia · 2014-01-09

Review

871. The modified atkins diet in refractory epilepsy.

Sharma S, Jain P · Epilepsy research and treatment · 2014-01-30

Review

872. The ketogenic diet: initiation at goal calories versus gradual caloric advancement.

Bansal S, Cramp L, Blalock D, Zelleke T, Carpenter J, Kao A · Pediatric neurology · 2013-11-05

Other

873. Childhood absence epilepsy successfully treated with the paleolithic ketogenic diet.

Clemens Z, Kelemen A, Fogarasi A, Tóth C · Neurology and therapy · 2013-09-21

Systematic review / meta-analysis

874. Therapeutic Success of the Ketogenic Diet as a Treatment Option for Epilepsy: a Meta-analysis.

Li HF, Zou Y, Ding G · Iranian journal of pediatrics · 2013-01-10

Clinical trial / intervention

875. A decade of the modified Atkins diet (2003–2013): Results, insights, and future directions.

Kossoff EH, Cervenka MC, Henry BJ, Haney CA, Turner Z · Epilepsy & behavior : E&B · 2014-01-04

Other

876. Modified Atkins diet vs classic ketogenic formula in intractable epilepsy.

El-Rashidy OF, Nassar MF, Abdel-Hamid IA, Shatla RH, Abdel-Hamid MH, Gabr SS, Mohamed SG, El-Sayed WS, Shaaban SY · Acta neurologica Scandinavica · 2013-05-16

Preclinical / mechanistic

877. Ketogenic diet improves forelimb motor function after spinal cord injury in rodents.

Streijger F, Plunet WT, Lee JH, Liu J, Lam CK, Park S, Hilton BJ, Fransen BL, Matheson KA, Assinck P, Kwon BK, Tetzlaff W · PloS one · 2013-11-04

Case report / case series

878. Ketogenic diet in 3 cases of childhood refractory status epilepticus.

Sort R, Born AP, Pedersen KN, Fonsmark L, Uldall P · European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society · 2013-06-14

Preclinical / mechanistic

879. Consumption of a low-carbohydrate and high-fat diet (the ketogenic diet) exaggerates biotin deficiency in mice.

Yuasa M, Matsui T, Ando S, Ishii Y, Sawamura H, Ebara S, Watanabe T · Nutrition (Burbank, Los Angeles County, Calif.) · 2012-12-27

Other

880. Epilepsy characteristics and psychosocial factors associated with ketogenic diet success.

McNamara NA, Carbone LA, Shellhaas RA · Journal of child neurology · 2012-09-21

Observational human study

881. Prognostic factors of infantile spasms: role of treatment options including a ketogenic diet.

Lee J, Lee JH, Yu HJ, Lee M · Brain & development · 2013-07-12

Review

882. Can we predict a favourable response to Ketogenic Diet Therapies for drug-resistant epilepsy?

Schoeler NE, Cross JH, Sander JW, Sisodiya SM · Epilepsy research · 2013-06-30

Observational human study

883. Movement disorders in GLUT1 deficiency syndrome respond to the modified Atkins diet.

Leen WG, Mewasingh L, Verbeek MM, Kamsteeg EJ, van de Warrenburg BP, Willemsen MA · Movement disorders : official journal of the Movement Disorder Society · 2013-06-25

Case report / case series

884. Intravenous initiation and maintenance of ketogenic diet: proof of concept in super-refractory status epilepticus.

Strzelczyk A, Reif PS, Bauer S, Belke M, Oertel WH, Knake S, Rosenow F · Seizure · 2013-04-15

Review

885. The ketogenic diet in Dravet syndrome.

Laux L, Blackford R · Journal of child neurology · 2013-05-07

Other

886. [Changes in serum levels of selenium, zinc and copper in patients on a ketogenic diet using Ketonformula].

Hayashi A, Kumada T, Nozaki F, Hiejima I, Miyajima T, Fujii T · No to hattatsu = Brain and development · 2013-08-20

Other

887. Transitioning pediatric patients receiving ketogenic diets for epilepsy into adulthood.

Kossoff EH, Henry BJ, Cervenka MC · Seizure · 2013-04-06

Observational human study

888. Ketogenic diet for infantile spasms refractory to first-line treatments: an open prospective study.

Pires ME, Ilea A, Bourel E, Bellavoine V, Merdariu D, Berquin P, Auvin S · Epilepsy research · 2013-01-26

Preclinical / mechanistic

889. Seizure control by ketogenic diet-associated medium chain fatty acids.

Chang P, Terbach N, Plant N, Chen PE, Walker MC, Williams RS · Neuropharmacology · 2012-11-20

Preclinical / mechanistic

890. Therapeutic ketosis with ketone ester delays central nervous system oxygen toxicity seizures in rats.

D'Agostino DP, Pilla R, Held HE, Landon CS, Puchowicz M, Brunengraber H, Ari C, Arnold P, Dean JB · American journal of physiology. Regulatory, integrative and comparative physiology · 2013-04-03

Observational human study

891. [Influence of ketogenic diet on the clinical effects and electroencephalogram features in 31 children with pharmacoresistant epileptic encephalopathy].

Li BM, Tong LL, Jia GJ, Wang JW, Lei GF, Yin P, Sun RP · Zhonghua er ke za zhi = Chinese journal of pediatrics · 2013-08-15

Observational human study

892. [Prospective multicenter study on long-term ketogenic diet therapy for intractable childhood epilepsy].

Ketogenic Diet Study Group of the Subspecialty Group of Neurology, the Society of Pediatrics, Chinese Medical Association · Zhonghua er ke za zhi = Chinese journal of pediatrics · 2013-08-10

Observational human study

893. Can children with hyperlipidemia receive ketogenic diet for medication-resistant epilepsy?

Liu YM, Lowe H, Zak MM, Kobayashi J, Chan VW, Donner EJ · Journal of child neurology · 2013-02-20

Other

894. The impact of a ketogenic diet and liver dysfunction on serum very long-chain fatty acids levels.

Stradomska TJ, Bachański M, Pawłowska J, Syczewska M, Stolarczyk A, Tylki-Szymańska A · Lipids · 2013-01-31

Preclinical / mechanistic

895. Combination treatment of epilepsy with ketogenic diet and concurrent pharmacological inhibition of cytochrome P450 2E1.

Palmer M · Medical hypotheses · 2013-01-28

Observational human study

896. Efficacy and safety of the ketogenic diet in Chinese children.

Suo C, Liao J, Lu X, Fang K, Hu Y, Chen L, Cao D, Huang T, Li B, Li C · Seizure · 2012-12-28

Review

897. Ketogenic diet.

Dhamija R, Eckert S, Wirrell E · The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques · 2013-02-20

Randomized clinical trial

898. Use of the modified Atkins diet for treatment of refractory childhood epilepsy: a randomized controlled trial.

Sharma S, Sankhyan N, Gulati S, Agarwala A · Epilepsia · 2013-01-07

Preclinical / mechanistic

899. Changes in brain cortex sensitivity to epileptogens under conditions of ketogenic diet.

Kresyun VI, Polyasny VA, Godovan VV, Godlevsky LS · Bulletin of experimental biology and medicine · 2013-03-15

Other

900. Effects of ketogenic diet on the clinical and electroencephalographic features of children with drug therapy-resistant epilepsy.

Li B, Tong L, Jia G, Sun R · Experimental and therapeutic medicine · 2012-11-22

Observational human study

901. Catch-up growth after long-term implementation and weaning from ketogenic diet in pediatric epileptic patients.

Kim JT, Kang HC, Song JE, Lee MJ, Lee YJ, Lee EJ, Lee JS, Kim HD · Clinical nutrition (Edinburgh, Scotland) · 2012-06-30

Other

902. Ketogenic diet effects on cognition, mood, and psychosocial adjustment in children.

Lambrechts DA, Bovens MJ, de la Parra NM, Hendriksen JG, Aldenkamp AP, Majoie MJ · Acta neurologica Scandinavica · 2012-06-12

Case report / case series

903. Lipoid pneumonia--a case of refractory pneumonia in a child treated with ketogenic diet.

Buda P, Wieteska-Klimczak A, Własienko A, Mazur A, Ziołkowski J, Jaworska J, Kościesza A, Dunin-Wąsowicz D, Książyk J · Pneumonologia i alergologia polska · 2013-08-22

Review

904. Ketogenic diet in epileptic encephalopathies.

Sharma S, Tripathi M · Epilepsy research and treatment · 2013-07-10

Guideline / consensus

905. Ketogenic diet: an early option for epilepsy treatment, instead of a last choice only.

Wang HS, Lin KL · Biomedical journal · 2013-03-22

Randomized clinical trial

906. Medium-chain triglyceride ketogenic diet, an effective treatment for drug-resistant epilepsy and a comparison with other ketogenic diets.

Liu YM, Wang HS · Biomedical journal · 2013-03-22

Other

907. Ketogenic diet therapy for epilepsy management.

Wei FC · Biomedical journal · 2013-03-22

Randomized clinical trial

908. Effects of a ketogenic diet on brain metabolism in epilepsy.

Korsholm K, Law I · Clinical nuclear medicine · 2012-12-18

Review

909. [Adenosine and the anti-epileptic actions of ketogenic diets].

Li TF, Luan GM · Zhonghua er ke za zhi = Chinese journal of pediatrics · 2013-01-18

Preclinical / mechanistic

910. A ketogenic diet did not prevent effects on the ectonucleotidases pathway promoted by lithium-pilocarpine-induced status epilepticus in rat hippocampus.

da Silveira VG, da Silva RS, de Paula Cognato G, Capiotti KM, Figueiró F, Bogo MR, Bonan CD, Perry ML, Battastini AM · Metabolic brain disease · 2012-09-05

Case report / case series

911. Case report of pyruvate dehydrogenase deficiency with unusual increase of fats during ketogenic diet treatment.

Di Pisa V, Cecconi I, Gentile V, Di Pietro E, Marchiani V, Verrotti A, Franzoni E · Journal of child neurology · 2012-02-28

Preclinical / mechanistic

912. Ketogenic diet reduces Smac/Diablo and cytochrome c release and attenuates neuronal death in a mouse model of limbic epilepsy.

Luan G, Zhao Y, Zhai F, Chen Y, Li T · Brain research bulletin · 2012-07-11

Other

913. The use of ketogenic diet in special situations: expanding use in intractable epilepsy and other neurologic disorders.

Lee M · Korean journal of pediatrics · 2012-09-14

Clinical trial / intervention

914. Ketogenic diet in early myoclonic encephalopathy due to non ketotic hyperglycinemia.

Cusmai R, Martinelli D, Moavero R, Dionisi Vici C, Vigevano F, Castana C, Elia M, Bernabei S, Bevivino E · European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society · 2012-01-18

Observational human study

915. Safety and role of ketogenic parenteral nutrition for intractable childhood epilepsy.

Jung DE, Kang HC, Lee JS, Lee EJ, Kim HD · Brain & development · 2011-12-20

Other

916. How do parents find out about the ketogenic diet?

Kossoff EH, Doerrer SS, Turner Z · Epilepsy & behavior : E&B · 2012-06-05

Observational human study

917. Various indications for a modified Atkins diet in intractable childhood epilepsy.

Kim YM, Vaidya VV, Khusainov T, Kim HD, Kim SH, Lee EJ, Lee YM, Lee JS, Kang HC · Brain & development · 2011-10-15

Review

918. Alternative diets to the classical ketogenic diet--can we be more liberal?

Miranda MJ, Turner Z, Magrath G · Epilepsy research · 2012-07-06

Observational human study

919. [Super-refractory status epilepticus: treatment with ketogenic diet in pediatrics].

Vaccarezza M, Silva W, Maxit C, Agosta G · Revista de neurologia · 2012-06-22

Review

920. Carnitine, nutritional supplementation and discontinuation of ketogenic diet therapies.

Neal EG, Zupec-Kania B, Pfeifer HH · Epilepsy research · 2012-06-15

Review

921. Is the ketogenic diet effective in specific epilepsy syndromes?

Nangia S, Caraballo RH, Kang HC, Nordli DR, Scheffer IE · Epilepsy research · 2012-03-15

Review

922. Modulation of oxidative stress and mitochondrial function by the ketogenic diet.

Milder J, Patel M · Epilepsy research · 2011-11-09

Preclinical / mechanistic

923. Purines and neuronal excitability: links to the ketogenic diet.

Masino SA, Kawamura M, Ruskin DN, Geiger JD, Boison D · Epilepsy research · 2011-08-30

Review

924. Ketogenic diets: where do we go from here?

Kossoff EH, Cross JH · Epilepsy research · 2011-01-24

Review

925. The ketogenic diet: what has science taught us?

Rho JM, Stafstrom CE · Epilepsy research · 2011-08-30

Guideline / consensus

926. Long-term monitoring of the ketogenic diet: Do's and Don'ts.

Bergqvist AG · Epilepsy research · 2011-08-19

Review

927. Myoclonic astatic epilepsy and the use of the ketogenic diet.

Bergqvist AG · Epilepsy research · 2011-05-31

Clinical trial / intervention

928. Long-term follow-up of children treated with the modified Atkins diet.

Chen W, Kossoff EH · Journal of child neurology · 2012-04-24

Case report / case series

929. Ketogenic diet: rapid onset of selenium deficiency-induced cardiac decompensation.

Sirikonda NS, Patten WD, Phillips JR, Mullett CJ · Pediatric cardiology · 2012-02-25

Observational human study

930. Efficacy of the ketogenic diet in Lennox-Gastaut syndrome: a retrospective review of one institution's experience and summary of the literature.

Lemmon ME, Terao NN, Ng YT, Reisig W, Rubenstein JE, Kossoff EH · Developmental medicine and child neurology · 2012-03-22

Observational human study

932. Effects of the ketogenic diet on nutritional status, resting energy expenditure, and substrate oxidation in patients with medically refractory epilepsy: a 6-month prospective observational study.

Tagliabue A, Bertoli S, Trentani C, Borrelli P, Veggiotti P · Clinical nutrition (Edinburgh, Scotland) · 2011-10-20

Other

933. The ketogenic diet as a treatment option in adults with chronic refractory epilepsy: efficacy and tolerability in clinical practice.

Lambrechts DA, Wielders LH, Aldenkamp AP, Kessels FG, de Kinderen RJ, Majoie MJ · Epilepsy & behavior : E&B · 2012-02-25

Clinical trial / intervention

934. Efficacy of the ketogenic diet: which epilepsies respond?

Thammongkol S, Vears DF, Bicknell-Royle J, Nation J, Draffin K, Stewart KG, Scheffer IE, Mackay MT · Epilepsia · 2012-02-06

Preclinical / mechanistic

935. CSF levels of dopamine and serotonin, but not norepinephrine, metabolites are influenced by the ketogenic diet in children with epilepsy.

Dahlin M, Månsson JE, Åmark P · Epilepsy research · 2012-01-11

Preclinical / mechanistic

936. Ketogenic diet protects against epileptogenesis as well as neuronal loss in amygdaloid-kindling seizures.

Jiang Y, Yang Y, Wang S, Ding Y, Guo Y, Zhang MM, Wen SQ, Ding MP · Neuroscience letters · 2011-12-13

Case report / case series

937. Successful treatment of type 1 diabetes and seizures with combined ketogenic diet and insulin.

Aguirre Castaneda RL, Mack KJ, Lteif A · Pediatrics · 2012-01-16

Other

938. The ketogenic diet is well tolerated and can be effective in patients with argininosuccinate lyase deficiency and refractory epilepsy.

Peuscher R, Dijsselhof ME, Abeling NG, Van Rijn M, Van Spronsen FJ, Bosch AM · JIMD reports · 2011-12-25

Other

939. The use of ketogenic diet in pediatric patients with epilepsy.

Misiewicz Runyon A, So TY · ISRN pediatrics · 2012-08-28

Case report / case series

940. [Ketogenic diet may control seizures by increasing the binding potential of the benzodiazepine receptor: a speculation from the [11C] flumazenil-PET study].

Kumada T, Nishii R, Higashi T, Miyajima T, Oda N, Shimomura H, Saito K, Fujii T · No to hattatsu = Brain and development · 2012-02-23

Other

941. The ketogenic diet and the QT interval.

Sharma S, Gulati S · Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia · 2011-11-30

Clinical trial / intervention

942. Efficacy and tolerability of modified Atkins diet in Japanese children with medication-resistant epilepsy.

Kumada T, Miyajima T, Oda N, Shimomura H, Saito K, Fujii T · Brain & development · 2011-01-15

Preclinical / mechanistic

943. Ketogenic diet-induced peroxisome proliferator-activated receptor-γ activation decreases neuroinflammation in the mouse hippocampus after kainic acid-induced seizures.

Jeong EA, Jeon BT, Shin HJ, Kim N, Lee DH, Kim HJ, Kang SS, Cho GJ, Choi WS, Roh GS · Experimental neurology · 2011-09-14

Clinical trial / intervention

944. The ketogenic diet for medically and surgically refractory status epilepticus in the neurocritical care unit.

Cervenka MC, Hartman AL, Venkatesan A, Geocadin RG, Kossoff EH · Neurocritical care · 2011-04-28

Guideline / consensus

945. [Experience with ketogenic diet as treatment for refractory epilepsy].

Ramírez-Camacho A, Meavilla S, Catalán N, Gutiérrez A, Campistol J · Revista de neurologia · 2011-10-21

Review

946. The ketogenic and related diets in adolescents and adults--a review.

Payne NE, Cross JH, Sander JW, Sisodiya SM · Epilepsia · 2011-10-17

Observational human study

947. The role of ketogenic diet in the treatment of refractory status epilepticus.

Nam SH, Lee BL, Lee CG, Yu HJ, Joo EY, Lee J, Lee M · Epilepsia · 2011-10-17

Preclinical / mechanistic

948. Protective effect of the ketogenic diet in Scn1a mutant mice.

Dutton SB, Sawyer NT, Kalume F, Jumbo-Lucioni P, Borges K, Catterall WA, Escayg A · Epilepsia · 2011-07-29

Case report / case series

949. [Risk of pellagroid dermatitis during a ketogenic diet in an epileptic patient].

Schmutz JL, Trechot P · Annales de dermatologie et de venereologie · 2011-06-14

Observational human study

950. Long-term follow-up of the ketogenic diet for refractory epilepsy: multicenter Argentinean experience in 216 pediatric patients.

Caraballo R, Vaccarezza M, Cersósimo R, Rios V, Soraru A, Arroyo H, Agosta G, Escobal N, Demartini M, Maxit C, Cresta A, Marchione D, Carniello M, Paníco L · Seizure · 2011-07-16

Preclinical / mechanistic

951. Neuron-restrictive silencer factor is not required for the antiepileptic effect of the ketogenic diet.

Hu XL, Cheng X, Fei J, Xiong ZQ · Epilepsia · 2011-07-18

Randomized clinical trial

952. Efficacy of 4:1 (classic) versus 2.5:1 ketogenic ratio diets in refractory epilepsy in young children: a randomized open labeled study.

Raju KN, Gulati S, Kabra M, Agarwala A, Sharma S, Pandey RM, Kalra V · Epilepsy research · 2011-05-28

Observational human study

953. Is there an ideal way to discontinue the ketogenic diet?

Worden LT, Turner Z, Pyzik PL, Rubenstein JE, Kossoff EH · Epilepsy research · 2011-05-04

Review

954. Refractory epilepsy and the ketogenic diet: pathophysiological aspects and possible implications in dental practice.

Sharma A, Mathur VP · Journal of the Indian Society of Pedodontics and Preventive Dentistry · 2011-10-12

Case report / case series

955. [Remarkable effect of a modified ketogenic diet in a boy with focal seizures followed by epileptic spasms in a cluster].

Takahashi H, Imai K, Takayama R, Mine J, Ohtani S, Ikeda H, Kubota Y, Takahashi Y, Inoue Y, Fujiwara T · No to hattatsu = Brain and development · 2011-08-02

Preclinical / mechanistic

956. A ketogenic diet suppresses seizures in mice through adenosine A₁ receptors.

Masino SA, Li T, Theofilas P, Sandau US, Ruskin DN, Fredholm BB, Geiger JD, Aronica E, Boison D · The Journal of clinical investigation · 2011-06-23

Clinical trial / intervention

957. Ketogenic diet also benefits Dravet syndrome patients receiving stiripentol: a prospective pilot study.

Nabbout R, Copioli C, Chipaux M, Chemaly N, Desguerre I, Dulac O, Chiron C · Epilepsia · 2011-05-13

Clinical trial / intervention

958. A modified Atkins diet is promising as a treatment for glucose transporter type 1 deficiency syndrome.

Ito Y, Oguni H, Ito S, Oguni M, Osawa M · Developmental medicine and child neurology · 2011-04-18

Other

959. The fat is in the fire: ketogenic diet for refractory status epilepticus.

Kossoff E · Epilepsy currents · 2011-08-20

Case report / case series

960. Myoclonic astatic epilepsy and the role of the ketogenic diet.

Mulligan JE, Mandelbaum DE · Medicine and health, Rhode Island · 2011-06-30

Other

961. The ketogenic diet for epilepsy therapy in children: quo vadis?

Pluta R, Jabłoński M · Nutrition (Burbank, Los Angeles County, Calif.) · 2010-10-13

Observational human study

962. Ketogenic diet in the treatment of seizures associated with hypothalamic hamartomas.

Chapman KE, Kim DY, Rho JM, Ng YT, Kerrigan JF · Epilepsy research · 2011-03-04

Guideline / consensus

963. The ketogenic diet for Dravet syndrome and other epileptic encephalopathies: an Italian consensus.

Veggiotti P, Burlina A, Coppola G, Cusmai R, De Giorgis V, Guerrini R, Tagliabue A, Dalla Bernardina B · Epilepsia · 2011-04-06

Guideline / consensus

964. [Ketogenic diet for intractable childhood epilepsy; as an early option as well as a last resort].

Ito S, Oguni H · Brain and nerve = Shinkei kenkyu no shinpo · 2011-03-29

Clinical trial / intervention

965. Early EEG improvement after ketogenic diet initiation.

Kessler SK, Gallagher PR, Shellhaas RA, Clancy RR, Bergqvist AG · Epilepsy research · 2011-02-23

Case report / case series

966. The modified Atkins diet for intractable epilepsy may be associated with late-onset egg-induced anaphylactic reaction: a case report.

Levy Y, Peleg-Weiss L, Goldberg-Stern H · Nutrition (Burbank, Los Angeles County, Calif.) · 2010-07-02

Clinical trial / intervention

967. Danish study of a modified Atkins diet for medically intractable epilepsy in children: can we achieve the same results as with the classical ketogenic diet?

Miranda MJ, Mortensen M, Povlsen JH, Nielsen H, Beniczky S · Seizure · 2010-12-03

Observational human study

968. Prospective study of the modified atkins diet in combination with a ketogenic liquid supplement during the initial month.

Kossoff EH, Dorward JL, Turner Z, Pyzik PL · Journal of child neurology · 2010-09-10

Review

969. Do patients with absence epilepsy respond to ketogenic diets?

Groomes LB, Pyzik PL, Turner Z, Dorward JL, Goode VH, Kossoff EH · Journal of child neurology · 2010-07-20

Randomized clinical trial

970. Research into the (Cost-) effectiveness of the ketogenic diet among children and adolescents with intractable epilepsy: design of a randomized controlled trial.

de Kinderen RJ, Lambrechts DA, Postulart D, Kessels AG, Hendriksen JG, Aldenkamp AP, Evers SM, Majoie MH · BMC neurology · 2011-01-25

Other

971. The ketogenic diet 2011: how it works.

Politi K, Shemer-Meiri L, Shuper A, Aharoni S · Epilepsy research and treatment · 2011-06-05

Case report / case series

972. [The ketogenic diet as an effective treatment for Ohtahara syndrome].

Ishii M, Shimono M, Senju A, Kusuhara K, Shiota N · No to hattatsu = Brain and development · 2011-03-16

Preclinical / mechanistic

973. The ketogenic diet changes metabolite levels in hippocampal extracellular fluid.

Samala R, Klein J, Borges K · Neurochemistry international · 2010-11-09

Observational human study

974. Will seizure control improve by switching from the modified Atkins diet to the traditional ketogenic diet?

Kossoff EH, Bosarge JL, Miranda MJ, Wiemer-Kruel A, Kang HC, Kim HD · Epilepsia · 2010-11-10

Other

975. Matthew Williams and his ketogenic diet.

Williams E · Seizure · 2010-12-29

Clinical trial / intervention

976. Ketogenic diet treatment in adults with refractory epilepsy.

Klein P, Janousek J, Barber A, Weissberger R · Epilepsy & behavior : E&B · 2010-07-08

Observational human study

977. A pilot study of the modified Atkins diet for Sturge-Weber syndrome.

Kossoff EH, Borsage JL, Comi AM · Epilepsy research · 2010-10-08

Case report / case series

978. Pellagroid dermatitis during a ketogenic diet and anti-epileptic therapy.

Patrizi A, Bianchi F, Volpi L, Lesi C, Andrini L, Fantoni E, Neri I · European journal of dermatology : EJD · 2010-10-12

Preclinical / mechanistic

979. Does ketogenic diet alter seizure sensitivity and cell loss following fluid percussion injury?

Schwartzkroin PA, Wenzel HJ, Lyeth BG, Poon CC, Delance A, Van KC, Campos L, Nguyen DV · Epilepsy research · 2010-09-21

Other

980. Valproic acid and phenobarbital blood levels during the first month of treatment with the ketogenic diet.

Coppola G, Verrotti A, D'Aniello A, Arcieri S, Operto FF, Della Corte R, Ammendola E, Pascotto A · Acta neurologica Scandinavica · 2010-11-17

Case report / case series

981. Ketogenic diet in a patient with Angelman syndrome.

Evangeliou A, Doulioglou V, Haidopoulou K, Aptouramani M, Spilioti M, Varlamis G · Pediatrics international : official journal of the Japan Pediatric Society · 2010-10-01

Other

982. Efficacy of ketogenic diet in severe refractory status epilepticus initiating fever induced refractory epileptic encephalopathy in school age children (FIRES).

Nabbout R, Mazzuca M, Hubert P, Peudennier S, Allaire C, Flurin V, Aberastury M, Silva W, Dulac O · Epilepsia · 2010-08-31

Randomized clinical trial

983. Does a preference for fatty foods prior to commencing treatment with the ketogenic diet predict the efficacy of this diet?

Dekker CF, van den Hurk TA, van Nieuwenhuizen O · Seizure · 2010-07-23

Preclinical / mechanistic

984. Ketogenic diet exhibits neuroprotective effects in hippocampus but fails to prevent epileptogenesis in the lithium-pilocarpine model of mesial temporal lobe epilepsy in adult rats.

Linard B, Ferrandon A, Koning E, Nehlig A, Raffo E · Epilepsia · 2010-07-14

Observational human study

985. Long-term outcome and tolerability of the ketogenic diet in drug-resistant childhood epilepsy--the Austrian experience.

Dressler A, Stöcklin B, Reithofer E, Benninger F, Freilinger M, Hauser E, Reiter-Fink E, Seidl R, Trimmel-Schwahofer P, Feucht M · Seizure · 2010-07-02

Preclinical / mechanistic

986. Seizure tests distinguish intermittent fasting from the ketogenic diet.

Hartman AL, Zheng X, Bergbower E, Kennedy M, Hardwick JM · Epilepsia · 2010-04-30

Review

987. Question 1: efficacy of the ketogenic diet in difficult childhood epilepsies.

Archives of disease in childhood · 2010-06-17

Review

988. The ketogenic diet in childhood epilepsy: where are we now?

Cross JH, McLellan A, Neal EG, Philip S, Williams E, Williams RE · Archives of disease in childhood · 2010-04-23

Review

989. Ketogenic diets: an historical antiepileptic therapy with promising potentialities for the aging brain.

Balietti M, Casoli T, Di Stefano G, Giorgetti B, Aicardi G, Fattoretti P · Ageing research reviews · 2010-02-24

Other

990. Long-term outcomes of children treated with the ketogenic diet in the past.

Patel A, Pyzik PL, Turner Z, Rubenstein JE, Kossoff EH · Epilepsia · 2010-02-01

Other

991. Ketogenic diet for treatment of epilepsy.

Rogovik AL, Goldman RD · Canadian family physician Medecin de famille canadien · 2010-06-16

Other

992. The ketogenic diet: an appropriate first-line therapy?

Kossoff EH · Expert review of neurotherapeutics · 2010-06-04

Clinical trial / intervention

993. Urolithiasis on the ketogenic diet with concurrent topiramate or zonisamide therapy.

Paul E, Conant KD, Dunne IE, Pfeifer HH, Lyczkowski DA, Linshaw MA, Thiele EA · Epilepsy research · 2010-05-13

Preclinical / mechanistic

994. Effect of ketogenic diet on nucleotide hydrolysis and hepatic enzymes in blood serum of rats in a lithium-pilocarpine-induced status epilepticus.

da Silveira VG, de Paula Cognato G, Müller AP, Figueiró F, Bonan CD, Perry ML, Battastini AM · Metabolic brain disease · 2010-05-05

Case report / case series

995. Type 1 diabetes and epilepsy: efficacy and safety of the ketogenic diet.

Dressler A, Reithofer E, Trimmel-Schwahofer P, Klebermasz K, Prayer D, Kasprian G, Rami B, Schober E, Feucht M · Epilepsia · 2010-03-18

Clinical trial / intervention

996. The ketogenic diet in treatment of two adults with prolonged nonconvulsive status epilepticus.

Wusthoff CJ, Kranick SM, Morley JF, Christina Bergqvist AG · Epilepsia · 2009-10-20

Case report / case series

997. Renal stone associated with the ketogenic diet in a 5-year old girl with intractable epilepsy.

Choi JN, Song JE, Shin JI, Kim HD, Kim MJ, Lee JS · Yonsei medical journal · 2010-04-09

Clinical trial / intervention

998. Ketogenic diet for the treatment of catastrophic epileptic encephalopathies in childhood.

Coppola G, Verrotti A, Ammendola E, Operto FF, Corte RD, Signoriello G, Pascotto A · European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society · 2009-07-25

Other

999. Glucose transporter type 1 deficiency: ketogenic diet in three patients with atypical phenotype.

Veggiotti P, Teutonico F, Alfei E, Nardocci N, Zorzi G, Tagliabue A, De Giorgis V, Balottin U · Brain & development · 2009-06-09

Other

1000. Use of the ketogenic diet and dietary practices in the UK.

Lord K, Magrath G · Journal of human nutrition and dietetics : the official journal of the British Dietetic Association · 2010-05-22

Case report / case series

1001. Modified Atkins diet for the treatment of nonconvulsive status epilepticus in children.

Kumada T, Miyajima T, Kimura N, Saito K, Shimomura H, Oda N, Fujii T · Journal of child neurology · 2009-09-24

Other

1002. Ketogenic diet in epileptic children: clinical and laboratory assessment.

Tumas R, Lopes Cardoso A, Marques-Dias MJ, Vieira MA · Nutricion hospitalaria · 2010-05-08

Guideline / consensus

1003. [Use of ketogenic diet in children in France from 2001 to 2008].

Auvin S, Porta N, Pourrat M, Bellavoine V, Vallée L · Revue neurologique · 2009-08-07

Review

1004. Purines and the Anti-Epileptic Actions of Ketogenic Diets.

Masino SA, Kawamura M, Ruskin DN, Gawryluk J, Chen X, Geiger JD · The open neuroscience journal · 2011-11-09

Review

1005. Ketosis and the ketogenic diet, 2010: advances in treating epilepsy and other disorders.

Freeman JM, Kossoff EH · Advances in pediatrics · 2010-11-09

Review

1006. [Anticonvulsant and neuroprotective effects of the ketogenic diet].

Choragiewicz T, Zarnowska I, Gasior M, Zarnowski T · Przeglad lekarski · 2010-08-07

Case report / case series

1007. [Modified Atkins diet brought back the joy of life to a developmentally severely disabled youth].

Arvio M, Kuisma L, Pöntinen M · Duodecim; laaketieteellinen aikakauskirja · 2010-07-06

Other

1008. Blood beta-hydroxybutyrate correlates better with seizure reduction due to ketogenic diet than do ketones in the urine.

van Delft R, Lambrechts D, Verschuure P, Hulsman J, Majoie M · Seizure · 2009-12-03

Observational human study

1009. Effectiveness of the ketogenic diet in a broad range of seizure types and EEG features for severe childhood epilepsies.

Beniczky S, Jose Miranda M, Alving J, Heber Povlsen J, Wolf P · Acta neurologica Scandinavica · 2009-11-26

Clinical trial / intervention

1010. Branched chain amino acids as adjunctive therapy to ketogenic diet in epilepsy: pilot study and hypothesis.

Evangeliou A, Spilioti M, Doulioglou V, Kalaidopoulou P, Ilias A, Skarpalezou A, Katsanika I, Kalamitsou S, Vasilaki K, Chatziioanidis I, Garganis K, Pavlou E, Varlamis S, Nikolaidis N · Journal of child neurology · 2009-08-17

Review

1011. Adenosine, ketogenic diet and epilepsy: the emerging therapeutic relationship between metabolism and brain activity.

Masino SA, Kawamura M, Wasser CD, Pomeroy LT, Ruskin DN · Current neuropharmacology · 2009-02-23

Observational human study

1012. [Re-evaluation of ketogenic diet therapy for childhood refractory epilepsy].

Oguni M, Oguni H, Ito S, Ito Y, Osawa M · No to hattatsu = Brain and development · 2009-09-22

Review

1013. Tonic and atonic seizures: medical therapy and ketogenic diet.

Vining EP · Epilepsia · 2009-08-26

Preclinical / mechanistic

1014. Ketogenic diet treatment abolishes seizure periodicity and improves diurnal rhythmicity in epileptic Kcna1-null mice.

Fenoglio-Simeone KA, Wilke JC, Milligan HL, Allen CN, Rho JM, Maganti RK · Epilepsia · 2009-06-01

Other

1015. Ketogenic diet in the management of childhood epilepsy.

Cross JH · Indian pediatrics · 2009-09-01

Case report / case series

1016. Rational treatment options with AEDs and ketogenic diet in Landau-Kleffner syndrome: still waiting after all these years.

Lagae L · Epilepsia · 2009-08-18

Observational human study

1017. Ketogenic diet in Indian children with uncontrolled epilepsy.

Nathan JK, Purandare AS, Parekh ZB, Manohar HV · Indian pediatrics · 2009-04-01

Observational human study

1018. The influence of concurrent anticonvulsants on the efficacy of the ketogenic diet.

Morrison PF, Pyzik PL, Hamdy R, Hartman AL, Kossoff EH · Epilepsia · 2009-04-06

Case report / case series

1019. [Case report of dentatorubral pallidoluysian atrophy in a patient on a ketogenic diet].

Matsuura K, Morimoto Y, Sugimura M, Taki K, Maeda M, Niwa H · Masui. The Japanese journal of anesthesiology · 2009-06-16

Preclinical / mechanistic

1020. Improvement in motor and exploratory behavior in Rett syndrome mice with restricted ketogenic and standard diets.

Mantis JG, Fritz CL, Marsh J, Heinrichs SC, Seyfried TN · Epilepsy & behavior : E&B · 2009-02-26

Clinical trial / intervention

1021. Comparison of seizure reduction and serum fatty acid levels after receiving the ketogenic and modified Atkins diet.

Porta N, Vallée L, Boutry E, Fontaine M, Dessein AF, Joriot S, Cuisset JM, Cuvellier JC, Auvin S · Seizure · 2009-02-04

Preclinical / mechanistic

1022. The ketogenic diet has no effect on the expression of spike-and-wave discharges and nutrient transporters in genetic absence epilepsy rats from Strasbourg.

Nehlig A, Dufour F, Klinger M, Willing LB, Simpson IA, Vannucci SJ · Journal of neurochemistry · 2009-04-28

Preclinical / mechanistic

1023. Beta-hydroxybutyrate alters GABA-transaminase activity in cultured astrocytes.

Suzuki Y, Takahashi H, Fukuda M, Hino H, Kobayashi K, Tanaka J, Ishii E · Brain research · 2009-03-11

Observational human study

1024. Ketogenic diet in the treatment of refractory continuous spikes and waves during slow sleep.

Nikanorova M, Miranda MJ, Atkins M, Sahlholdt L · Epilepsia · 2009-02-12

Observational human study

1025. Modified Atkins diet to children and adolescents with medical intractable epilepsy.

Weber S, Mølgaard C, Karentaudorf, Uldall P · Seizure · 2008-12-03

Randomized clinical trial

1026. [The ketogenic diet and its variants: state of the art].

Porta N, Vallée L, Boutry E, Auvin S · Revue neurologique · 2008-11-21

Other

1027. The ketogenic diet: it's about 'time'.

Kossoff EH · Developmental medicine and child neurology · 2009-04-02

Review

1028. Ketogenic diets: evidence for short- and long-term efficacy.

Kossoff EH, Rho JM · Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2008-11-30

Review

1029. The ketogenic diet: proposed mechanisms of action.

Nylen K, Likhodii S, Burnham WM · Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2008-11-29

Case report / case series

1030. Ketogenic diet in Alpers-Huttenlocher syndrome.

Joshi CN, Greenberg CR, Mhanni AA, Salman MS · Pediatric neurology · 2008-07-21

Observational human study

1031. The ketogenic diet improves recently worsened focal epilepsy.

Villeneuve N, Pinton F, Bahi-Buisson N, Dulac O, Chiron C, Nabbout R · Developmental medicine and child neurology · 2008-02-03

Clinical trial / intervention

1032. The ketogenic diet: additional information from a crossover study.

Freeman JM · Journal of child neurology · 2009-02-02

Preclinical / mechanistic

1033. Ketogenic diet attenuates kainic acid-induced hippocampal cell death by decreasing AMPK/ACC pathway activity and HSP70.

Jeon BT, Lee DH, Kim KH, Kim HJ, Kang SS, Cho GJ, Choi WS, Roh GS · Neuroscience letters · 2009-01-31

Preclinical / mechanistic

1034. Ketogenic diet is antiepileptogenic in pentylenetetrazole kindled mice and decrease levels of N-acylethanolamines in hippocampus.

Hansen SL, Nielsen AH, Knudsen KE, Artmann A, Petersen G, Kristiansen U, Hansen SH, Hansen HS · Neurochemistry international · 2008-11-30

Other

1035. The ketogenic diet and epilepsy: is adenosine the missing link?

Masino SA, Geiger JD · Epilepsia · 2009-02-14

Other

1036. Seizures, EEG events, and the ketogenic diet: response.

Bleasel A · Epilepsia · 2009-02-14

Other

1037. The ketogenic diet in epilepsy--monitoring of efficacy.

Cross JH · Epilepsia · 2009-02-14

Other

1038. Seizures, EEG events, and the ketogenic diet.

Freeman JM · Epilepsia · 2009-02-14

Other

1039. Commentary on "Optimal clinical management of children receiving the ketogenic diet: recommendations of the International Ketogenic Diet Study Group".

Bodensteiner J · Epilepsia · 2009-02-14

Other

1040. The ketogenic diet: what do the recommendations mean?

Duchowny M · Epilepsia · 2009-02-14

Guideline / consensus

1041. Optimal clinical management of children receiving the ketogenic diet: recommendations of the International Ketogenic Diet Study Group.

Kossoff EH, Zupec-Kania BA, Amark PE, Ballaban-Gil KR, Christina Bergqvist AG, Blackford R, Buchhalter JR, Caraballo RH, Helen Cross J, Dahlin MG, Donner EJ, Klepper J, Jehle RS, Kim HD, Christiana Liu YM, Nation J, Nordli DR, Pfeifer HH, Rho JM, Stafstrom CE, Thiele EA, Turner Z, Wirrell EC, Wheless JW, Veggiotti P, Vining EP, Charlie Foundation, Practice Committee of the Child Neurology Society, Practice Committee of the Child Neurology Society, International Ketogenic Diet Study Group · Epilepsia · 2008-09-23

Observational human study

1042. Growth dependence on insulin-like growth factor-1 during the ketogenic diet.

Spulber G, Spulber S, Hagenäs L, Amark P, Dahlin M · Epilepsia · 2008-08-25

Randomized clinical trial

1043. A blinded, crossover study of the efficacy of the ketogenic diet.

Freeman JM, Vining EP, Kossoff EH, Pyzik PL, Ye X, Goodman SN · Epilepsia · 2008-08-19

Randomized clinical trial

1044. The ketogenic diet, four score and seven years later.

Nordli DR · Nature clinical practice. Neurology · 2008-06-06

Clinical trial / intervention

1045. Ketogenic diet treatment in adults with refractory epilepsy: a prospective pilot study.

Mosek A, Natour H, Neufeld MY, Shiff Y, Vaisman N · Seizure · 2008-08-03

Case report / case series

1046. Intractable seizures, developmental delay, and the ketogenic diet.

Harris ML, Patel H, Garg BP · Seminars in pediatric neurology · 2008-12-17

Other

1047. Progressive bone mineral content loss in children with intractable epilepsy treated with the ketogenic diet.

Bergqvist AG, Schall JI, Stallings VA, Zemel BS · The American journal of clinical nutrition · 2008-12-10

Case report / case series

1048. Sudden cardiac death in association with the ketogenic diet.

Bank IM, Shemie SD, Rosenblatt B, Bernard C, Mackie AS · Pediatric neurology · 2007-09-14

Clinical trial / intervention

1049. The ketogenic diet in a pill: is this possible?

Rho JM, Sankar R · Epilepsia · 2008-12-17

Review

1050. Neuroprotective effects of the ketogenic diet.

Noh HS, Kim YS, Choi WS · Epilepsia · 2008-12-17

Review

1051. The contribution of norepinephrine and orexigenic neuropeptides to the anticonvulsant effect of the ketogenic diet.

Weinshenker D · Epilepsia · 2008-12-17

Review

1052. Energy metabolism as part of the anticonvulsant mechanism of the ketogenic diet.

Bough K · Epilepsia · 2008-12-17

Review

1053. Peroxisome proliferator-activated receptor alpha and the ketogenic diet.

Cullingford T · Epilepsia · 2008-12-17

Review

1055. Mouse models: the ketogenic diet and polyunsaturated fatty acids.

Borges K · Epilepsia · 2008-12-17

Review

1057. Does the effectiveness of the ketogenic diet in different epilepsies yield insights into its mechanisms?

Hartman AL · Epilepsia · 2008-12-17

Review

1058. Cultural challenges in using the ketogenic diet in Asian countries.

Seo JH, Kim HD · Epilepsia · 2008-12-17

Observational human study

1059. The modified Atkins diet.

Kossoff EH, Dorward JL · Epilepsia · 2008-12-17

Review

1060. Use of the ketogenic diet in neonates and infants.

Rubenstein JE · Epilepsia · 2008-12-17

Review

1061. Long-term management of the ketogenic diet: seizure monitoring, nutrition, and supplementation.

Zupec-Kania B, Zupanc ML · Epilepsia · 2008-12-17

Guideline / consensus

1063. International consensus statement on clinical implementation of the ketogenic diet: agreement, flexibility, and controversy.

Kossoff EH · Epilepsia · 2008-12-17

Systematic review / meta-analysis

1064. The ketogenic diet--update on recent clinical trials.

Cross JH, Neal EG · Epilepsia · 2008-12-17

Review

1065. History of the ketogenic diet.

Wheless JW · Epilepsia · 2008-12-17

Other

1066. Epilepsia. Ketogenic diet and treatments. Introduction/perspectives.

Stafstrom CE, Zupec-Kania B, Rho JM · Epilepsia · 2008-12-17

Clinical trial / intervention

1067. The ketogenic diet: uses in epilepsy and other neurologic illnesses.

Barañano KW, Hartman AL · Current treatment options in neurology · 2008-11-08

Preclinical / mechanistic

1068. Ketogenic diet-fed rats have increased fat mass and phosphoenolpyruvate carboxykinase activity.

Ribeiro LC, Chittó AL, Müller AP, Rocha JK, Castro da Silva M, Quincozes-Santos A, Nardin P, Rotta LN, Ziegler DR, Gonçalves CA, Da Silva RS, Perry ML, Gottfried C · Molecular nutrition & food research · 2008-07-26

Other

1069. The effect of the ketogenic diet on hippocampal GluR5 and Glu(6 mRNA expression and Q/R site editing in the kainate-induced epilepsy model.

Xu X, Sun R, Jin R · Epilepsy & behavior : E&B · 2008-07-07

Preclinical / mechanistic

1070. Anticonvulsant profile of a balanced ketogenic diet in acute mouse seizure models.

Samala R, Willis S, Borges K · Epilepsy research · 2008-06-18

Case report / case series

1071. Case report: scurvy in an epileptic child on a ketogenic diet with oral complications.

Willmott NS, Bryan RA · European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2008-09-17

Case report / case series

1072. The modified Atkins diet: a potential treatment for developing countries.

Kossoff EH, Dorward JL, Molinero MR, Holden KR · Epilepsia · 2008-09-11

Observational human study

1073. A pilot trial with modified Atkins' diet in adult patients with refractory epilepsy.

Carrette E, Vonck K, de Herdt V, Dewaele I, Raedt R, Goossens L, Van Zandijcke M, Wadman W, Thadani V, Boon P · Clinical neurology and neurosurgery · 2008-06-24

Clinical trial / intervention

1074. Effect of a ketogenic diet on EEG: analysis of sample entropy.

Yum MK, Jung KY, Kang HC, Kim HD, Shon YM, Kang JK, Lee IK, Park KJ, Kwon OY · Seizure · 2008-04-18

Preclinical / mechanistic

1075. Ketogenic diet does not disturb neurogenesis in the dentate gyrus in rats.

Strandberg J, Kondziella D, Thorlin T, Asztely F · Neuroreport · 2008-07-17

Other

1076. Growth of children on classical and medium-chain triglyceride ketogenic diets.

Neal EG, Chaffe HM, Edwards N, Lawson MS, Schwartz RH, Cross JH · Pediatrics · 2008-08-05

Observational human study

1077. Long-term outcome of the ketogenic diet for intractable childhood epilepsy with focal malformation of cortical development.

Jung DE, Kang HC, Kim HD · Pediatrics · 2008-08-05

Preclinical / mechanistic

1078. The ketogenic diet increases mitochondrial glutathione levels.

Jarrett SG, Milder JB, Liang LP, Patel M · Journal of neurochemistry · 2008-05-05

Other

1079. Polyunsaturated fatty acids and cerebrospinal fluid from children on the ketogenic diet open a voltage-gated K channel: a putative mechanism of antiseizure action.

Xu XP, Erichsen D, Börjesson SI, Dahlin M, Amark P, Elinder F · Epilepsy research · 2008-05-02

Review

1080. Are purines mediators of the anticonvulsant/neuroprotective effects of ketogenic diets?

Masino SA, Geiger JD · Trends in neurosciences · 2008-05-09

Other

1081. From observations to trials: the ketogenic diet and epilepsy.

Wiznitzer M · The Lancet. Neurology · 2008-05-02

Other

1082. Improving tolerability of the ketogenic diet in patients with abnormal endoscopic findings.

Jung DE, Chung JY, Kang HC, Kim HD · Brain & development · 2008-01-28

Preclinical / mechanistic

1083. Antioxidant capacity contributes to protection of ketone bodies against oxidative damage induced during hypoglycemic conditions.

Haces ML, Hernández-Fonseca K, Medina-Campos ON, Montiel T, Pedraza-Chaverri J, Massieu L · Experimental neurology · 2008-01-26

Review

1084. The ketogenic diet and epilepsy.

Kim DY, Rho JM · Current opinion in clinical nutrition and metabolic care · 2008-02-28

Case report / case series

1085. Modified Atkins diet therapy for a case with glucose transporter type 1 deficiency syndrome.

Ito S, Oguni H, Ito Y, Ishigaki K, Ohinata J, Osawa M · Brain & development · 2007-09-14

Case report / case series

1086. [Interest of the ketogenic diet in a refractory status epilepticus in adults].

Bodenant M, Moreau C, Sejourné C, Auvin S, Delval A, Cuisset JM, Derambure P, Destée A, Defebvre L · Revue neurologique · 2008-01-31

Preclinical / mechanistic

1087. Effects of the ketogenic diet on neurogenesis after kainic acid-induced seizures in mice.

Kwon YS, Jeong SW, Kim DW, Choi ES, Son BK · Epilepsy research · 2008-01-16

Preclinical / mechanistic

1088. Efficacy of the ketogenic diet in the 6-Hz seizure test.

Hartman AL, Lyle M, Rogawski MA, Gasior M · Epilepsia · 2007-12-06

Other

1089. When do seizures usually improve with the ketogenic diet?

Kossoff EH, Laux LC, Blackford R, Morrison PF, Pyzik PL, Hamdy RM, Turner Z, Nordli DR · Epilepsia · 2007-11-19

Preclinical / mechanistic

1090. Calorie-restricted ketogenic diet increases thresholds to all patterns of pentylenetetrazol-induced seizures: critical importance of electroclinical assessment.

Raffo E, François J, Ferrandon A, Koning E, Nehlig A · Epilepsia · 2007-10-15

Clinical trial / intervention

1091. A prospective study of the modified Atkins diet for intractable epilepsy in adults.

Kossoff EH, Rowley H, Sinha SR, Vining EP · Epilepsia · 2007-10-05

Clinical trial / intervention

1092. Influence of the ketogenic diet on 24-hour electroencephalogram in children with epilepsy.

Remahl S, Dahlin MG, Amark PE · Pediatric neurology · 2007-03-22

Preclinical / mechanistic

1093. Is the antiepileptic effect of the ketogenic diet due to ketones?

Mainardi P, Albano C · Medical hypotheses · 2007-08-21

Other

1094. [Ketogenic diet for the treatment of refractory epilepsy].

Chapman AH · Arquivos de neuro-psiquiatria · 2007-12-21

Review

1095. Complications and consequences of epilepsy surgery, ketogenic diet, and vagus nerve stimulation.

Wilong AA · Seminars in pediatric neurology · 2007-12-12

Other

1096. Effects of ketogenic diet on epileptiform activity in children with therapy resistant epilepsy.

Hallböök T, Köhler S, Rosén I, Lundgren J · Epilepsy research · 2007-11-08

Observational human study

1097. Decreased relative efficacy of the ketogenic diet for children with surgically approachable epilepsy.

Stainman RS, Turner Z, Rubenstein JE, Kossoff EH · Seizure · 2007-06-04

Preclinical / mechanistic

1098. Ketogenic diet prevents seizure and reduces myoclonic jerks in rats with cardiac arrest-induced cerebral hypoxia.

Tai KK, Truong DD · Neuroscience letters · 2007-08-10

Other

1099. Commentary on the effects of a ketogenic diet enriched with omega-3 polyunsaturated fatty acids on plasma phospholipid fatty acid profile in children with drug-resistant epilepsy.

Taha AY, McIntyre Burnham W · Epilepsy research · 2007-09-11

Other

1100. Ketogenic diet: electrophysiological effects on the normal human cortex.

Cantello R, Varrasi C, Tarletti R, Cecchin M, D'Andrea F, Veggiotti P, Bellomo G, Monaco F · Epilepsia · 2007-06-11

Clinical trial / intervention

1101. Predictive power of first morning glucose and the ketogenic diet.

Bergqvist AG, Schall JI, Richard EL, Gallagher PR, Stallings VA · Neuropediatrics · 2007-12-07

Observational human study

1102. Children with seizures exhibit preferences for foods compatible with the ketogenic diet.

Amari A, Dahlquist L, Kossoff EH, Vining EP, Trescher WH, Slifer KJ · Epilepsy & behavior : E&B · 2007-06-14

Other

1103. Ketogenic diet for the treatment of refractory epilepsy: a 10 year experience in children.

Freitas A, Paz JA, Casella EB, Marques-Dias MJ · Arquivos de neuro-psiquiatria · 2006-06-26

Case report / case series

1104. Home-guided use of the ketogenic diet in a patient for more than 20 years.

Kossoff EH, Turner Z, Bergey GK · Pediatric neurology · 2006-11-21

Case report / case series

1105. [Glucose transponer type 1 deficiency síndrome (GLUT-1 SD) treated with ketogenic diet. Report of one case].

Cornejo VE, Cabello JF, Colombo MC, Raimann EB · Revista medica de Chile · 2007-07-09

Preclinical / mechanistic

1106. Evidence against enhanced glutamate transport in the anticonvulsant mechanism of the ketogenic diet.

Bough KJ, Paquet M, Paré JF, Hassel B, Smith Y, Hall RA, Dingledine R · Epilepsy research · 2007-04-09

Randomized clinical trial

1107. A randomized, crossover comparison of daily carbohydrate limits using the modified Atkins diet.

Kossoff EH, Turner Z, Bluml RM, Pyzik PL, Vining EP · Epilepsy & behavior : E&B · 2007-02-26

Clinical trial / intervention

1108. Kidney stones and the ketogenic diet: risk factors and prevention.

Sampath A, Kossoff EH, Furth SL, Pyzik PL, Vining EP · Journal of child neurology · 2007-07-11

Randomized clinical trial

1109. Efficacy and tolerability of the ketogenic diet according to lipid:nonlipid ratios--comparison of 3:1 with 4:1 diet.

Seo JH, Lee YM, Lee JS, Kang HC, Kim HD · Epilepsia · 2007-03-26

Preclinical / mechanistic

1110. The anticonvulsant activity of acetone, the major ketone body in the ketogenic diet, is not dependent on its metabolites acetol, 1,2-propanediol, methylglyoxal, or pyruvic acid.

Gasior M, French A, Joy MT, Tang RS, Hartman AL, Rogawski MA · Epilepsia · 2007-03-26

Review

1111. The ketogenic diet: one decade later.

Freeman JM, Kossoff EH, Hartman AL · Pediatrics · 2007-03-03

Other

1112. Plasma phospholipid fatty acids are influenced by a ketogenic diet enriched with n-3 fatty acids in children with epilepsy.

Dahlin M, Hjelte L, Nilsson S, Amark P · Epilepsy research · 2006-12-05

Review

1113. [The role of the ketogenic diet in the management of epilepsy].

Starbała A, Bawa SH · Roczniki Panstwowego Zakladu Higieny · 2007-08-23

Observational human study

1114. Is hospitalization really necessary during the introduction of the ketogenic diet?

Rizzutti S, Ramos AM, Muszkat M, Gabbai AA · Journal of child neurology · 2007-07-05

Review

1115. The ketogenic diet and brain metabolism of amino acids: relationship to the anticonvulsant effect.

Yudkoff M, Daikhin Y, Melø TM, Nissim I, Sonnewald U, Nissim I · Annual review of nutrition · 2007-04-21

Observational human study

1116. Discontinuing the ketogenic diet in seizure-free children: recurrence and risk factors.

Martinez CC, Pyzik PL, Kossoff EH · Epilepsia · 2007-01-24

Observational human study

1117. Use of a modified Atkins diet in intractable childhood epilepsy.

Kang HC, Lee HS, You SJ, Kang du C, Ko TS, Kim HD · Epilepsia · 2007-01-24

Observational human study

1118. Safe and effective use of the ketogenic diet in children with epilepsy and mitochondrial respiratory chain complex defects.

Kang HC, Lee YM, Kim HD, Lee JS, Slama A · Epilepsia · 2007-01-24

Observational human study

1119. Combined ketogenic diet and vagus nerve stimulation: rational polytherapy?

Kossoff EH, Pyzik PL, Rubenstein JE, Bergqvist AG, Buchhalter JR, Donner EJ, Nordli DR, Wheless JW · Epilepsia · 2007-01-24

Other

1120. Vitamin D status in children with intractable epilepsy, and impact of the ketogenic diet.

Bergqvist AG, Schall JI, Stallings VA · Epilepsia · 2007-01-24

Other

1121. Ketogenic diet improves sleep quality in children with therapy-resistant epilepsy.

Hallböök T, Lundgren J, Rosén I · Epilepsia · 2007-01-24

Review

1122. Anticonvulsant mechanisms of the ketogenic diet.

Bough KJ, Rho JM · Epilepsia · 2007-01-24

Case report / case series

1123. Clinical aspects of the ketogenic diet.

Hartman AL, Vining EP · Epilepsia · 2007-01-24

Clinical trial / intervention

1124. Possible mechanism for the effect of ketogenic diet in cases of uncontrolled seizures. The reconsideration of acetone theory.

Kalapos MP · Medical hypotheses · 2006-12-12

Review

1125. [The ketogenic diet -- role of the pediatric nurse].

Leiendecker B, Klepper J · Kinderkrankenschwester : Organ der Sektion Kinderkrankenpflege · 2007-01-24

Other

1126. Use of the ketogenic diet as a long-term treatment for intractable epilepsy.

Murphy P · Developmental medicine and child neurology · 2006-12-13

Observational human study

1127. Long-term use of the ketogenic diet in the treatment of epilepsy.

Groesbeck DK, Bluml RM, Kossoff EH · Developmental medicine and child neurology · 2006-05-08

Other

1128. Ketogenic diet protects the hippocampus from kainic acid toxicity by inhibiting the dissociation of bad from 14-3-3.

Noh HS, Kim YS, Kim YH, Han JY, Park CH, Kang AK, Shin HS, Kang SS, Cho GJ, Choi WS · Journal of neuroscience research · 2006-10-24

Preclinical / mechanistic

1129. Effect of ketogenic diet on hippocampus mossy fiber sprouting and GluR5 expression in kainic acid induced rat model.

Xu XP, Sun RP, Jin RF · Chinese medical journal · 2006-12-01

Other

1130. Ketogenic diet. Update and application.

Bahassan NA, Jan MM · Neurosciences (Riyadh, Saudi Arabia) · 2012-01-24

Observational human study

1131. Ketogenic diet for treatment of infantile spasms.

Eun SH, Kang HC, Kim DW, Kim HD · Brain & development · 2006-05-11

Observational human study

1132. [Asymptomatic carnitine depletion on ketogenic diet in patients with pharmacoresistant epilepsies].

Liebhaber G, Pascher B, Gempel K, Baumeister FA · Klinische Padiatrie · 2006-09-02

Preclinical / mechanistic

1133. A ketogenic diet and diallyl sulfide do not elevate afterdischarge thresholds in adult kindled rats.

Nylen K, Likhodii SS, Hum KM, Burnham WM · Epilepsy research · 2006-06-19

Preclinical / mechanistic

1134. Mitochondrial biogenesis in the anticonvulsant mechanism of the ketogenic diet.

Bough KJ, Wetherington J, Hassel B, Pare JF, Gawryluk JW, Greene JG, Shaw R, Smith Y, Geiger JD, Dingledine RJ · Annals of neurology · 2006-06-30

Review

1135. State of the ketogenic diet(s) in epilepsy.

Huffman J, Kossoff EH · Current neurology and neuroscience reports · 2006-07-11

Other

1136. Plasma levels of antiepileptic drugs in children on the ketogenic diet.

Dahlin MG, Beck OM, Amark PE · Pediatric neurology · 2005-08-01

Systematic review / meta-analysis

1137. A systematic review of the use of the ketogenic diet in childhood epilepsy.

Keene DL · Pediatric neurology · 2005-11-09

Clinical trial / intervention

1138. Monitoring of ketogenic diet for carnitine metabolites by subcutaneous microdialysis.

Hack A, Busch V, Pascher B, Busch R, Bieger I, Gempel K, Baumeister FA · Pediatric research · 2006-05-11

Clinical trial / intervention

1139. Plasma free carnitine in epilepsy children, adolescents and young adults treated with old and new antiepileptic drugs with or without ketogenic diet.

Coppola G, Epifanio G, Auricchio G, Federico RR, Resicato G, Pascotto A · Brain & development · 2006-01-10

Observational human study

1140. Ketogenic diet in patients with myoclonic-astatic epilepsy.

Caraballo RH, Cersósimo RO, Sakr D, Cresta A, Escobal N, Fejerman N · Epileptic disorders : international epilepsy journal with videotape · 2005-08-22

Clinical trial / intervention

1141. The effects of the ketogenic diet in refractory partial seizures with reference to tuberous sclerosis.

Coppola G, Klepper J, Ammendola E, Fiorillo M, della Corte R, Capano G, Pascotto A · European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society · 2006-04-24

Systematic review / meta-analysis

1142. Efficacy of the ketogenic diet as a treatment option for epilepsy: meta-analysis.

Henderson CB, Filloux FM, Alder SC, Lyon JL, Caplin DA · Journal of child neurology · 2006-08-12

Other

1143. The importance of parental expectations of cognitive improvement for their children with epilepsy prior to starting the ketogenic diet.

Farasat S, Kossoff EH, Pillas DJ, Rubenstein JE, Vining EP, Freeman JM · Epilepsy & behavior : E&B · 2006-01-30

Preclinical / mechanistic

1144. A ketogenic diet and knockout of the norepinephrine transporter both reduce seizure severity in mice.

Martillotti J, Weinshenker D, Liles LC, Eagles DA · Epilepsy research · 2005-12-13

Preclinical / mechanistic

1145. Ketogenic diet decreases the level of proenkephalin mRNA induced by kainic acid in the mouse hippocampus.

Noh HS, Kim DW, Kang SS, Kim YH, Cho GJ, Choi WS · Neuroscience letters · 2005-11-21

Preclinical / mechanistic

1146. Increased nitric oxide caused by the ketogenic diet reduces the onset time of kainic acid-induced seizures in ICR mice.

Noh HS, Kim DW, Cho GJ, Choi WS, Kang SS · Brain research · 2006-02-03

Preclinical / mechanistic

1147. [Effect of ketogenic diet on hippocampus synaptic reorganization and GluR5 expression in kainic acid induced rat model of epilepsy].

Xu XP, Sun RP, Jin RF · Zhonghua er ke za zhi = Chinese journal of pediatrics · 2006-04-21

Guideline / consensus

1148. The ketogenic diet: from molecular mechanisms to clinical effects.

Freeman J, Veggiotti P, Lanzi G, Tagliabue A, Perucca E, Institute of Neurology IRCCS C. Mondino Foundation · Epilepsy research · 2006-03-09

Other

1149. The outcome of children with intractable seizures: a 3- to 6-year follow-up of 67 children who remained on the ketogenic diet less than one year.

Marsh EB, Freeman JM, Kossoff EH, Vining EP, Rubenstein JE, Pyzik PL, Hemingway C · Epilepsia · 2006-02-28

Case report / case series

1150. Anesthetic management of a pediatric patient on a ketogenic diet.

Ichikawa J, Nishiyama K, Ozaki K, Ikeda M, Takii Y, Ozaki M · Journal of anesthesia · 2005-10-06

Review

1151. The ketogenic diet in children with epilepsy.

Papandreou D, Pavlou E, Kalimeri E, Mavromichalis I · The British journal of nutrition · 2006-01-31

Other

1152. Breath acetone predicts plasma ketone bodies in children with epilepsy on a ketogenic diet.

Musa-Veloso K, Likhodii SS, Rarama E, Benoit S, Liu YM, Chartrand D, Curtis R, Carmant L, Lortie A, Comeau FJ, Cunnane SC · Nutrition (Burbank, Los Angeles County, Calif.) · 2005-09-23

Randomized clinical trial

1153. Fasting versus gradual initiation of the ketogenic diet: a prospective, randomized clinical trial of efficacy.

Bergqvist AG, Schall JI, Gallagher PR, Cnaan A, Stallings VA · Epilepsia · 2005-11-24

Review

1154. Use of the ketogenic diet as a treatment for epilepsy refractory to drug treatment.

Murphy P · Expert review of neurotherapeutics · 2005-11-09

Clinical trial / intervention

1155. Seizure control and acceptance of the ketogenic diet in GLUT1 deficiency syndrome: a 2- to 5-year follow-up of 15 children enrolled prospectively.

Klepper J, Scheffer H, Leiendecker B, Gertsen E, Binder S, Leferink M, Hertzberg C, Näke A, Voit T, Willemsen MA · Neuropediatrics · 2005-10-12

Case report / case series

1156. Tuberous sclerosis complex and the ketogenic diet.

Kossoff EH, Thiele EA, Pfeifer HH, McGrogan JR, Freeman JM · Epilepsia · 2005-09-30

Observational human study

1157. Ketogenic diet in patients with Dravet syndrome.

Caraballo RH, Cersósimo RO, Sakr D, Cresta A, Escobal N, Fejerman N · Epilepsia · 2005-09-09

Observational human study

1158. Safety and tolerability of the ketogenic diet in pediatric epilepsy: effects of valproate combination therapy.

Lyczkowski DA, Pfeifer HH, Ghosh S, Thiele EA · Epilepsia · 2005-09-09

Preclinical / mechanistic

1159. Despite transient ketosis, the classic high-fat ketogenic diet induces marked changes in fatty acid metabolism in rats.

Taha AY, Ryan MA, Cunnane SC · Metabolism: clinical and experimental · 2004-10-18

Preclinical / mechanistic

1160. Ketogenic diet decreases circulating concentrations of neuroactive steroids of female rats.

Rhodes ME, Talluri J, Harney JP, Frye CA · Epilepsy & behavior : E&B · 2005-03-08

Preclinical / mechanistic

1161. Transitory gliosis in the CA3 hippocampal region in rats fed on a ketogenic diet.

Silva MC, Rocha J, Pires CS, Ribeiro LC, Brolese G, Leite MC, Almeida LM, Tramontina F, Ziegler DR, Gonçalves CA · Nutritional neuroscience · 2006-02-24

Preclinical / mechanistic

1162. A comparison of the ability of a 4:1 ketogenic diet and a 6.3:1 ketogenic diet to elevate seizure thresholds in adult and young rats.

Nylen K, Likhodii S, Abdelmalik PA, Clarke J, Burnham WM · Epilepsia · 2005-08-03

Preclinical / mechanistic

1163. Ketogenic diet increases calbindin-D28k in the hippocampi of male ICR mice with kainic acid seizures.

Noh HS, Kang SS, Kim DW, Kim YH, Park CH, Han JY, Cho GJ, Choi WS · Epilepsy research · 2004-12-21

Observational human study

1164. The ketogenic diet in refractory childhood epilepsy.

Mackay MT, Bicknell-Royle J, Nation J, Humphrey M, Harvey AS · Journal of paediatrics and child health · 2005-07-15

Other

1165. The ketogenic diet influences the levels of excitatory and inhibitory amino acids in the CSF in children with refractory epilepsy.

Dahlin M, Elfving A, Ungerstedt U, Amark P · Epilepsy research · 2004-07-06

Other

1166. Children and the ketogenic diet.

Santoro KB, O'Flaherty T · Journal of the American Dietetic Association · 2005-05-11

Observational human study

1167. Changes in growth and seizure reduction in children on the ketogenic diet as a treatment for intractable epilepsy.

Peterson SJ, Tangney CC, Pimentel-Zablah EM, Hjelmgren B, Booth G, Berry-Kravis E · Journal of the American Dietetic Association · 2005-05-11

Review

1168. The ketogenic diet.

Sinha SR, Kossoff EH · The neurologist · 2005-04-30

Preclinical / mechanistic

1169. Ketogenic diet prevents clusterin accumulation induced by kainic acid in the hippocampus of male ICR mice.

Noh HS, Kim DW, Kang SS, Cho GJ, Choi WS · Brain research · 2004-06-17

Other

1170. Can you predict an immediate, complete, and sustained response to the ketogenic diet?

Than KD, Kossoff EH, Rubenstein JE, Pyzik PL, McGrogan JR, Vining EP · Epilepsia · 2005-04-09

Preclinical / mechanistic

1171. Effect of the ketogenic diet on the activity level of Wistar rats.

Murphy P, Likhodii SS, Hatamian M, McIntyre Burnham W · Pediatric research · 2004-12-07

Other

1172. Worldwide use of the ketogenic diet.

Kossoff EH, McGrogan JR · Epilepsia · 2005-02-01

Clinical trial / intervention

1173. Efficacy and safety of the ketogenic diet for intractable childhood epilepsy: Korean multicentric experience.

Kang HC, Kim YJ, Kim DW, Kim HD · Epilepsia · 2005-02-01

Clinical trial / intervention

1174. Ketogenic diet in pediatric epilepsy patients with gastrostomy feeding.

Hosain SA, La Vega-Talbott M, Solomon GE · Pediatric neurology · 2004-02-26

Observational human study

1175. Experience in the use of the ketogenic diet as early therapy.

Rubenstein JE, Kossoff EH, Pyzik PL, Vining EP, McGrogan JR, Freeman JM · Journal of child neurology · 2005-03-29

Review

1176. Antiepileptic popular ketogenic diet: emerging twists in an ancient story.

Vamecq J, Vallée L, Lesage F, Gressens P, Stables JP · Progress in neurobiology · 2005-01-27

Clinical trial / intervention

1177. Ketogenic diet in patients with Dravet syndrome and myoclonic epilepsies in infancy and early childhood.

Fejerman N, Caraballo R, Cersosimo R · Advances in neurology · 2004-10-29

Randomized clinical trial

1178. Benefits of the nonfasting ketogenic diet compared with the initial fasting ketogenic diet.

Kim DW, Kang HC, Park JC, Kim HD · Pediatrics · 2004-12-03

Preclinical / mechanistic

1179. Ketogenic diet fed rats have low levels of S100B in cerebrospinal fluid.

Ziegler DR, Oliveira DL, Pires C, Ribeiro L, Leite M, Mendez A, Gonçalves D, Tramontina F, Portela LV, Wofchuk ST, Perry ML, Gonçalves CA · Neuroscience research · 2004-06-23

Other

1180. The ketogenic diet does not alter brain expression of orexigenic neuropeptides.

Tabb K, Szot P, White SS, Liles LC, Weinshenker D · Epilepsy research · 2004-03-01

Preclinical / mechanistic

1181. Management of multifactorial idiopathic epilepsy in EL mice with caloric restriction and the ketogenic diet: role of glucose and ketone bodies.

Mantis JG, Centeno NA, Todorova MT, McGowan R, Seyfried TN · Nutrition & metabolism · 2004-10-19

Case report / case series

1182. [Ketogenic diet for intractable epilepsy in children and adolescents: report of six cases].

Vasconcelos MM, Azevedo PM, Esteves L, Brito AR, Olivaes MC, Herdy GV · Revista da Associacao Medica Brasileira (1992) · 2005-01-14

Observational human study

1183. [The ketogenic diet in German-speaking countries: update 2003].

Klepper J, Leiendecker B, Riemann E, Baumeister FA · Klinische Padiatrie · 2004-09-30

Randomized clinical trial

1184. Ketogenic diet: outpatient initiation, without fluid, or caloric restrictions.

Vaisleib II, Buchhalter JR, Zupanc ML · Pediatric neurology · 2003-10-21

Other

1185. Benefits of an all-liquid ketogenic diet.

Kossoff EH, McGrogan JR, Freeman JM · Epilepsia · 2004-08-27

Case report / case series

1186. Fatal propofol infusion syndrome in association with ketogenic diet.

Baumeister FA, Oberhoffer R, Liebhaber GM, Kunkel J, Eberhardt J, Holthausen H, Peters J · Neuropediatrics · 2004-08-26

Review

1187. The impact of early versus late anticonvulsant reduction after ketogenic diet initiation.

Kossoff EH, Pyzik PL, McGrogan JR, Rubenstein JE · Epilepsy & behavior : E&B · 2004-02-09

Preclinical / mechanistic

1188. Lack of long-term histopathologic changes in brain and skeletal muscle of mice treated with a ketogenic diet.

Rho JM, Sarnat HB, Sullivan PG, Robbins CA, Kim DW · Journal of child neurology · 2004-11-06

Clinical trial / intervention

1189. High plasma branched-chain amino acids:aromatic amino acids ratio in children on the ketogenic diet: a mechanism in controlling epilepsy.

Jirapinyo P, Kankirawatana P, Densupsoontorn N, Thamonsiri N, Wongarn R · Journal of the Medical Association of Thailand = Chotmaihet thangphaet · 2004-06-26

Review

1190. [Use of the ketogenic diet in the treatment of resistant epilepsy].

Suzić B, Vasiljević N, Savić-Abramović L, Paunović K · Srpski arhiv za celokupno lekarstvo · 2004-08-17

Review

1191. [Ketogenic diet as antiepileptic therapy: a description of the clinical experience and the multidisciplinary approach at the metabolic-neurogenetic clinic at the Wolfson Medical Center].

Ginzberg M, Watemberg N, Levi A, Gabai A, Nissenkorn A, Blumkin L, Vinkler C, Lev D, Lerman-Sagie T · Harefuah · 2004-04-07

Review

1192. Ketogenic diet, brain glutamate metabolism and seizure control.

Yudkoff M, Daikhin Y, Nissim I, Lazarow A, Nissim I · Prostaglandins, leukotrienes, and essential fatty acids · 2003-06-06

Other

1193. Metabolic and health implications of moderate ketosis and the ketogenic diet.

Cunnane SC · Prostaglandins, leukotrienes, and essential fatty acids · 2004-02-11

Other

1194. The ketogenic diet: a cautionary note.

Snead OC · Pediatric research · 2004-01-07

Other

1195. [Use of ketogenic diet in treatment of pharmacoresistant epilepsy].

Usacheva EL, Aĭvazian SO, Sorvacheva TN, Pyr'eva EA, Kon' IIa, Zenkov LR, Shorina MIu, Osipova KV, Prityko AG · Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova · 2004-09-07

Preclinical / mechanistic

1196. Anticonvulsant properties of acetone, a brain ketone elevated by the ketogenic diet.

Likhodii SS, Serbanescu I, Cortez MA, Murphy P, Snead OC, Burnham WM · Annals of neurology · 2003-08-02

Review

1197. Perspectives on the metabolic management of epilepsy through dietary reduction of glucose and elevation of ketone bodies.

Greene AE, Todorova MT, Seyfried TN · Journal of neurochemistry · 2003-07-16

Observational human study

1198. The ketogenic diet: adolescents can do it, too.

Mady MA, Kossoff EH, McGregor AL, Wheless JW, Pyzik PL, Freeman JM · Epilepsia · 2003-06-07

Preclinical / mechanistic

1199. Calorie restriction and ketogenic diet diminish neuronal excitability in rat dentate gyrus in vivo.

Bough KJ, Schwartzkroin PA, Rho JM · Epilepsia · 2003-06-07

Randomized clinical trial

1200. A prospective study: growth and nutritional status of children treated with the ketogenic diet.

Liu YM, Williams S, Basualdo-Hammond C, Stephens D, Curtis R · Journal of the American Dietetic Association · 2003-06-05

Other

1201. Kidney stones, carbonic anhydrase inhibitors, and the ketogenic diet.

Parmar MS · Epilepsia · 2003-05-20

Other

1202. [Ketogenic regime as anti-epileptic treatment: its use in 29 epileptic children].

François LL, Manel V, Rousselle C, David M · Archives de pediatrie : organe officiel de la Societe francaise de pediatrie · 2003-06-24

Preclinical / mechanistic

1203. Calorie restriction of a high-carbohydrate diet elevates the threshold of PTZ-induced seizures to values equal to those seen with a ketogenic diet.

Eagles DA, Boyd SJ, Kotak A, Allan F · Epilepsy research · 2003-05-14

Review

1204. The ketogenic diet for the treatment of epilepsy: a challenge for nutritional neuroscientists.

Stafstrom CE, Bough KJ · Nutritional neuroscience · 2003-05-02

Observational human study

1205. Selenium deficiency associated with cardiomyopathy: a complication of the ketogenic diet.

Bergqvist AG, Chee CM, Lutchka L, Rychik J, Stallings VA · Epilepsia · 2003-04-19

Case report / case series

1206. Basal ganglia injury as a complication of the ketogenic diet.

Erickson JC, Jabbari B, Difazio MP · Movement disorders : official journal of the Movement Disorder Society · 2003-04-03

Other

1207. In vivo measurement of brain metabolites using two-dimensional double-quantum MR spectroscopy--exploration of GABA levels in a ketogenic diet.

Wang ZJ, Bergqvist C, Hunter JV, Jin D, Wang DJ, Wehrli S, Zimmerman RA · Magnetic resonance in medicine · 2003-03-26

Other

1208. Elevated polyunsaturated fatty acids in blood serum obtained from children on the ketogenic diet.

Fraser DD, Whiting S, Andrew RD, Macdonald EA, Musa-Veloso K, Cunnane SC · Neurology · 2003-03-26

Review

1209. Therapeutics in pediatric epilepsy, Part 1: The new antiepileptic drugs and the ketogenic diet.

Jarrar RG, Buchhalter JR · Mayo Clinic proceedings · 2003-03-13

Preclinical / mechanistic

1210. The protective effect of a ketogenic diet on kainic acid-induced hippocampal cell death in the male ICR mice.

Noh HS, Kim YS, Lee HP, Chung KM, Kim DW, Kang SS, Cho GJ, Choi WS · Epilepsy research · 2003-02-11

Preclinical / mechanistic

1211. The effect of the 'classic' ketogenic diet on animal seizure models.

Thavendiranathan P, Chow C, Cunnane S, McIntyre Burnham W · Brain research · 2002-12-21

Observational human study

1212. Assessing the efficacy of antiepileptic treatments: the ketogenic diet.

Thiele EA · Epilepsia · 2003-08-16

Systematic review / meta-analysis

1213. Ketogenic diet for epilepsy.

Levy R, Cooper P · The Cochrane database of systematic reviews · 2003-08-15

Case report / case series

1214. Ketogenic diet in Rett syndrome.

Liebhaber GM, Riemann E, Baumeister FA · Journal of child neurology · 2003-03-29

Observational human study

1215. [Nutritional status and bone mineral mass in children treated with ketogenic diet].

Bertoli S, Striuli L, Testolin G, Cardinali S, Veggiotti P, Salvatori GC, Tagliabue A · Recenti progressi in medicina · 2003-02-01

Other

1216. On the anticonvulsant effect of acetone and the ketogenic diet.

Likhodii SS, Burnham WM · Epilepsia · 2002-12-04

Observational human study

1217. Growth of children on the ketogenic diet.

Vining EP, Pyzik P, McGrogan J, Hladky H, Anand A, Kriegler S, Freeman JM · Developmental medicine and child neurology · 2002-11-29

Review

1218. Intractable pediatric epilepsy: vagal nerve stimulation and the ketogenic diet.

Sheth RD, Stafstrom CE · Neurologic clinics · 2003-03-06

Other

1219. Introduction of a ketogenic diet in young infants.

Klepper J, Leiendecker B, Bredahl R, Athanassopoulos S, Heinen F, Gertsen E, Flörcken A, Metz A, Voit T · Journal of inherited metabolic disease · 2003-01-31

Clinical trial / intervention

1220. [Indications and results of nonpharmacological treatments of epilepsies: vagal stimulation, ketogenic diet and gamma rays].

Forcadas-Berdusán MI · Revista de neurologia · 2002-10-10

Observational human study

1221. Concomitant treatment with topiramate and ketogenic diet in pediatric epilepsy.

Takeoka M, Riviello JJ, Pfeifer H, Thiele EA · Epilepsia · 2002-08-30

Other

1222. Epilepsy and the ketogenic diet: assessment of ketosis in children using breath acetone.

Musa-Veloso K, Rarama E, Comeau F, Curtis R, Cunnane S · Pediatric research · 2002-08-24

Preclinical / mechanistic

1223. Potential role of polyunsaturates in seizure protection achieved with the ketogenic diet.

Cunnane SC, Musa K, Ryan MA, Whiting S, Fraser DD · Prostaglandins, leukotrienes, and essential fatty acids · 2002-09-27

Preclinical / mechanistic

1224. An anticonvulsant profile of the ketogenic diet in the rat.

Bough KJ, Gudi K, Han FT, Rathod AH, Eagles DA · Epilepsy research · 2002-08-30

Preclinical / mechanistic

1225. Ketogenic diet: does acetone stop seizures?

Likhodii SS, Burnham WM · Medical science monitor : international medical journal of experimental and clinical research · 2002-08-08

Review

1226. The ketogenic diet: uses and abuses.

Nordli D · Neurology · 2002-06-27

Case report / case series

1227. Pitfalls of ketogenic diet in a neonate.

Goyens P, De Laet C, Ranguelov N, Ferreiro C, Robert M, Dan B · Pediatrics · 2002-06-04

Preclinical / mechanistic

1228. Effects of acute inhibition of fatty acid oxidation on latency to seizure and concentrations of beta hydroxybutyrate in plasma of rats maintained on calorie restriction and/or the ketogenic diet.

Harney JP, Madara J, Madara J, I'Anson H · Epilepsy research · 2002-06-22

Review

1229. General anesthesia and the ketogenic diet: clinical experience in nine patients.

Valencia I, Pfeifer H, Thiele EA · Epilepsia · 2002-05-25

Preclinical / mechanistic

1230. The ketogenic diet upregulates expression of the gene encoding the key ketogenic enzyme mitochondrial 3-hydroxy-3-methylglutaryl-CoA synthase in rat brain.

Cullingford TE, Eagles DA, Sato H · Epilepsy research · 2002-06-07

Observational human study

1231. The ketogenic diet: a review of the experience at Connecticut Children's Medical Center.

DiMario FJ, Holland J · Pediatric neurology · 2002-05-07

Preclinical / mechanistic

1232. Acetoacetate, acetone, and dibenzylamine (a contaminant in l-(+)-beta-hydroxybutyrate) exhibit direct anticonvulsant actions in vivo.

Rho JM, Anderson GD, Donevan SD, White HS · Epilepsia · 2002-04-16

Observational human study

1233. Is a fast necessary when initiating the ketogenic diet?

Wirrell EC, Darwish HZ, Williams-Dyjur C, Blackman M, Lange V · Journal of child neurology · 2002-05-25

Observational human study

1234. Growth retardation in children with epilepsy on the ketogenic diet: a retrospective chart review.

Williams S, Basualdo-Hammond C, Curtis R, Schuller R · Journal of the American Dietetic Association · 2002-03-21

Other

1235. Medical costs are reduced when children with intractable epilepsy are successfully treated with the ketogenic diet.

Mandel A, Ballew M, Pina-Garza JE, Stalmasek V, Clemens LH · Journal of the American Dietetic Association · 2002-03-21

Observational human study

1236. The ketogenic diet in children, adolescents and young adults with refractory epilepsy: an Italian multicentric experience.

Coppola G, Veggiotti P, Cusmai R, Bertoli S, Cardinali S, Dionisi-Vici C, Elia M, Lispi ML, Sarnelli C, Tagliabue A, Toraldo C, Pascotto A · Epilepsy research · 2002-03-21

Preclinical / mechanistic

1237. Breath acetone as a measure of systemic ketosis assessed in a rat model of the ketogenic diet.

Likhodii SS, Musa K, Cunnane SC · Clinical chemistry · 2001-12-26

Clinical trial / intervention

1238. The ketogenic diet may have mood-stabilizing properties.

El-Mallakh RS, Paskitti ME · Medical hypotheses · 2002-03-29

Other

1239. [A ketogenic diet: is this a valid alternative in refractory epilepsy].

Galván Manso M, Arellano M, Sans A, Sanmartí FX, Gómez L, Vernet A, Campistol J · Revista de neurologia · 2002-01-11

Clinical trial / intervention

1240. Reasons for failure of the ketogenic diet.

Lightstone L, Shinnar S, Callahan CM, O'Dell C, Moshe SL, Ballaban-Gil KR · The Journal of neuroscience nursing : journal of the American Association of Neuroscience Nurses · 2002-01-05

Other

1241. 'Ketogenic diet and surgery'.

Hanna BG, Miller F · Developmental medicine and child neurology · 2002-01-05

Review

1242. Ketogenic diet, amino acid metabolism, and seizure control.

Yudkoff M, Daikhin Y, Nissim I, Lazarow A, Nissim I · Journal of neuroscience research · 2001-12-18

Observational human study

1243. [Complications of treatment of epilepsy by a ketogenic diet].

Ríos VG · Revista de neurologia · 2002-01-11

Other

1244. Carnitine levels and the ketogenic diet.

Berry-Kravis E, Booth G, Sanchez AC, Woodbury-Kolb J · Epilepsia · 2002-03-07

Review

1245. The carbohydrate and caloric content of concomitant medications for children with epilepsy on the ketogenic diet.

Lebel D, Morin C, Laberge M, Achim N, Carmant L · The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques · 2002-01-05

Preclinical / mechanistic

1246. Comparison of the anticonvulsant efficacies and neurotoxic effects of valproic acid, phenytoin, and the ketogenic diet.

Bough KJ, Eagles DA · Epilepsia · 2001-12-12

Observational human study

1247. The ketogenic diet: a 3- to 6-year follow-up of 150 children enrolled prospectively.

Hemingway C, Freeman JM, Pillas DJ, Pyzik PL · Pediatrics · 2001-10-03

Observational human study

1248. Efficacy of the ketogenic diet in focal versus generalized seizures.

Maydell BV, Wyllie E, Akhtar N, Kotagal P, Powaski K, Cook K, Weinstock A, Rothner AD · Pediatric neurology · 2001-10-06

Case report / case series

1249. Acute pancreatitis causing death in a child on the ketogenic diet.

Stewart WA, Gordon K, Camfield P · Journal of child neurology · 2001-09-29

Other

1250. The ketogenic diet: an effective medical therapy with side effects.

Wheless JW · Journal of child neurology · 2001-09-29

Preclinical / mechanistic

1251. Norepinephrine is required for the anticonvulsant effect of the ketogenic diet.

Szot P, Weinshenker D, Rho JM, Storey TW, Schwartzkroin PA · Brain research. Developmental brain research · 2001-08-17

Observational human study

1252. Ketogenic diet: an alternative treatment for refractory epilepsy in children.

Kankirawatana P, Jirapinyo P, Kankirawatana S, Wongarn R, Thamanasiri N · Journal of the Medical Association of Thailand = Chotmaihet thangphaet · 2002-01-05

Observational human study

1253. Experience with the ketogenic diet in infants.

Nordli DR, Kuroda MM, Carroll J, Koenigsberger DY, Hirsch LJ, Bruner HJ, Seidel WT, De Vivo DC · Pediatrics · 2001-07-04

Review

1254. [The return to the ketogenic diet. What role does it play in the treatment of refractory seizures of infancy?].

Moreno Villares JM, Oliveros-Leal L, Simón-Heras R, Mateos-Beato F · Revista de neurologia · 2001-09-20

Preclinical / mechanistic

1255. Re: Dietary fat, ketosis, and seizure resistance in rats on the ketogenic diet.

Bough KJ, Eagles DA · Epilepsy research · 2001-06-22

Observational human study

1256. Effects of ketogenic diet on development and behavior: preliminary report of a prospective study.

Pulsifer MB, Gordon JM, Brandt J, Vining EP, Freeman JM · Developmental medicine and child neurology · 2001-05-23

Review

1257. Vagus nerve stimulation and the ketogenic diet.

Wheless JW, Baumgartner J, Ghanbari C · Neurologic clinics · 2001-05-19

Preclinical / mechanistic

1258. Experiments in the rat pentylenetetrazole infusion threshold model of the ketogenic diet.

Likhodii S · Epilepsy research · 2001-05-05

Other

1259. Avoid unnecessary drug-related carbohydrates for patients consuming the ketogenic diet.

McGhee B, Katyal N · Journal of the American Dietetic Association · 2001-02-24

Observational human study

1260. Bruising and the ketogenic diet: evidence for diet-induced changes in platelet function.

Berry-Kravis E, Booth G, Taylor A, Valentino LA · Annals of neurology · 2001-02-24

Preclinical / mechanistic

1261. Timing of ketogenic diet initiation in an experimental epilepsy model.

Su SW, Cilio MR, Sogawa Y, Silveira DC, Holmes GL, Stafstrom CE · Brain research. Developmental brain research · 2001-01-13

Other

1262. The ketogenic diet: seizure control correlates better with serum beta-hydroxybutyrate than with urine ketones.

Gilbert DL, Pyzik PL, Freeman JM · Journal of child neurology · 2001-02-24

Observational human study

1263. Risk factors for urolithiasis in children on the ketogenic diet.

Furth SL, Casey JC, Pyzik PL, Neu AM, Docimo SG, Vining EP, Freeman JM, Fivush BA · Pediatric nephrology (Berlin, Germany) · 2000-11-30

Preclinical / mechanistic

1264. Dietary fat, ketosis, and seizure resistance in rats on the ketogenic diet.

Likhodii SS, Musa K, Mendonca A, Dell C, Burnham WM, Cunnane SC · Epilepsia · 2000-11-15

Observational human study

1265. [The ketogenic diet in infantile refractory epilepsy: electroclinical response, complications and secondary effects].

Panico LR, Demartini MG, Ríos VG, Carniello MA · Revista de neurologia · 2000-09-21

Preclinical / mechanistic

1266. The ketogenic diet inhibits epileptogenesis in EL mice: a genetic model for idiopathic epilepsy.

Todorova MT, Tandon P, Madore RA, Stafstrom CE, Seyfried TN · Epilepsia · 2000-08-29

Other

1267. Nephrolithiasis associated with the ketogenic diet.

Kielb S, Koo HP, Bloom DA, Faerber GJ · The Journal of urology · 2000-07-14

Systematic review / meta-analysis

1268. Ketogenic diet for the treatment of refractory epilepsy in children: A systematic review of efficacy.

Lefevre F, Aronson N · Pediatrics · 2000-04-01

Other

1269. Dietary practices and use of the ketogenic diet in the UK.

Magrath G, MacDonald A, Whitehouse W · Seizure · 2000-06-14

Other

1270. The ketogenic diet in refractory epilepsy: the experience of Children's Hospital of Pittsburgh.

Katyal NG, Koehler AN, McGhee B, Foley CM, Crumrine PK · Clinical pediatrics · 2000-04-07

Preclinical / mechanistic

1271. The MCT ketogenic diet: effects on animal seizure models.

Thavendiranathan P, Mendonca A, Dell C, Likhodii SS, Musa K, Iracleous C, Cunnane SC, Burnham WM · Experimental neurology · 2000-02-25

Preclinical / mechanistic

1272. A ketogenic diet has different effects upon seizures induced by maximal electroshock and by pentylenetetrazole infusion.

Bough KJ, Matthews PJ, Eagles DA · Epilepsy research · 2000-01-21

Preclinical / mechanistic

1273. Ketone bodies do not directly alter excitatory or inhibitory hippocampal synaptic transmission.

Thio LL, Wong M, Yamada KA · Neurology · 2000-02-11

Other

1274. The ketogenic diet: a therapy in search of an explanation.

Stafstrom CE, Spencer S · Neurology · 2000-02-11

Case report / case series

1275. Perioperative management of a paediatric patient on the ketogenic diet.

McNeely JK · Paediatric anaesthesia · 2000-01-13

Preclinical / mechanistic

1276. Higher ketogenic diet ratios confer protection from seizures without neurotoxicity.

Bough KJ, Yao SG, Eagles DA · Epilepsy research · 1999-12-22

Observational human study

1277. The ketogenic diet for intractable epilepsy in adults: preliminary results.

Sirven J, Whedon B, Caplan D, Liporace J, Glosser D, O'Dwyer J, Sperling MR · Epilepsia · 1999-12-28

Other

1278. Growth and nutritional outcomes of children treated with the ketogenic diet.

Couch SC, Schwarzman F, Carroll J, Koenigsberger D, Nordli DR, Deckelbaum RJ, DeFelice AR · Journal of the American Dietetic Association · 1999-12-28

Other

1279. Development and evaluation of a ketogenic diet program.

MacCracken KA, Scalisi JC · Journal of the American Dietetic Association · 1999-12-28

Review

1280. Animal models of the ketogenic diet: what have we learned, what can we learn?

Stafstrom CE · Epilepsy research · 1999-12-10

Preclinical / mechanistic

1281. Age-dependent differences in flurothyl seizure sensitivity in mice treated with a ketogenic diet.

Rho JM, Kim DW, Robbins CA, Anderson GD, Schwartzkroin PA · Epilepsy research · 1999-12-10

Review

1282. Blood-brain barrier, ion homeostatis and epilepsy: possible implications towards the understanding of ketogenic diet mechanisms.

Janigro D · Epilepsy research · 1999-12-10

Review

1283. Metabolic and endocrine aspects of the ketogenic diet.

Sankar R, Sotero de Menezes M · Epilepsy research · 1999-12-10

Observational human study

1284. Clinical efficacy of the ketogenic diet.

Vining EP · Epilepsy research · 1999-12-10

Review

1285. Mechanisms underlying the anti-epileptic efficacy of the ketogenic diet.

Schwartzkroin PA · Epilepsy research · 1999-12-10

Case report / case series

1286. Treatment of acquired epileptic aphasia with the ketogenic diet.

Bergqvist AG, Chee CM, Lutchka LM, Brooks-Kayal AR · Journal of child neurology · 1999-12-11

Preclinical / mechanistic

1287. Path analysis shows that increasing ketogenic ratio, but not beta-hydroxybutyrate, elevates seizure threshold in the Rat.

Bough KJ, Chen RS, Eagles DA · Developmental neuroscience · 1999-11-27

Preclinical / mechanistic

1288. Electrophysiological observations in hippocampal slices from rats treated with the ketogenic diet.

Stafstrom CE, Wang C, Jensen FE · Developmental neuroscience · 1999-11-27

Case report / case series

1289. The implementation and maintenance of the Ketogenic Diet in children.

Casey JC, McGrogan J, Pillas D, Pyzik P, Freeman J, Vining EP · The Journal of neuroscience nursing : journal of the American Association of Neuroscience Nurses · 2000-01-14

Randomized clinical trial

1290. Seizures decrease rapidly after fasting: preliminary studies of the ketogenic diet.

Freeman JM, Vining EP · Archives of pediatrics & adolescent medicine · 1999-09-11

Observational human study

1291. Ketogenic diet in the treatment of refractory epilepsy in childhood.

Hassan AM, Keene DL, Whiting SE, Jacob PJ, Champagne JR, Humphreys P · Pediatric neurology · 1999-08-28

Clinical trial / intervention

1292. Medication cost reduction in children on the ketogenic diet: data from a prospective study.

Gilbert DL, Pyzik PL, Vining EP, Freeman JM · Journal of child neurology · 1999-11-26

Guideline / consensus

1293. The ketogenic diet. Central Nervous System Practice and Research Network of the American College of Clinical Pharmacy.

Bainbridge JL, Gidal BE, Ryan M · Pharmacotherapy · 1999-07-03

Preclinical / mechanistic

1294. Ketogenic diet reduces spontaneous seizures and mossy fiber sprouting in the kainic acid model.

Muller-Schwarze AB, Tandon P, Liu Z, Yang Y, Holmes GL, Stafstrom CE · Neuroreport · 1999-06-25

Preclinical / mechanistic

1295. Seizure resistance is dependent upon age and calorie restriction in rats fed a ketogenic diet.

Bough KJ, Valiyil R, Han FT, Eagles DA · Epilepsy research · 1999-05-08

Clinical trial / intervention

1296. Clinical experience of ketogenic diet on children with refractory epilepsy.

Mak SC, Chi CS, Wan CJ · Acta paediatrica Taiwanica = Taiwan er ke yi xue hui za zhi · 2000-07-27

Other

1297. Identification of cerebral acetone by 1H-MRS in patients with epilepsy controlled by ketogenic diet.

Seymour KJ, Bluml S, Sutherling J, Sutherling W, Ross BD · Magma (New York, N.Y.) · 1999-06-26

Other

1298. Biochemical abnormalities of the ketogenic diet in children.

Chesney D, Brouhard BH, Wyllie E, Powaski K · Clinical pediatrics · 1999-02-27

Preclinical / mechanistic

1299. A ketogenic diet increases the resistance to pentylenetetrazole-induced seizures in the rat.

Bough KJ, Eagles DA · Epilepsia · 1999-02-10

Other

1300. Correction: the role of the ketogenic diet in children with intractable seizures.

Gever LN · The Annals of pharmacotherapy · 1999-01-07

Clinical trial / intervention

1301. The efficacy of the ketogenic diet-1998: a prospective evaluation of intervention in 150 children.

Freeman JM, Vining EP, Pillas DJ, Pyzik PL, Casey JC, Kelly LM · Pediatrics · 1998-12-02

Randomized clinical trial

1302. A multicenter study of the efficacy of the ketogenic diet.

Vining EP, Freeman JM, Ballaban-Gil K, Camfield CS, Camfield PR, Holmes GL, Shinnar S, Shuman R, Trevathan E, Wheless JW · Archives of neurology · 1998-11-21

Clinical trial / intervention

1303. In vivo lactate and beta-hydroxybutyrate editing using a pure-phase refocusing pulse train.

Shen J, Novotny EJ, Rothman DL · Magnetic resonance in medicine · 1998-10-31

Other

1304. Ketogenic diet for the treatment of children with refractory epilepsy.

Tecnologica. MAP supplement. Blue Cross and Blue Shield Association. Medical Advisory Panel · 1999-05-26

Observational human study

1305. Complications of the ketogenic diet.

Ballaban-Gil K, Callahan C, O'Dell C, Pappo M, Moshé S, Shinnar S · Epilepsia · 1998-07-22

Case report / case series

1306. [Ketogenic diet--an alternative therapy for epilepsy in adults].

Schiff Y, Lerman-Sagie T · Harefuah · 2000-07-26

Other

1307. Ketogenic diet: a time-tested, effective, and safe method for treatment of intractable childhood epilepsy.

Freeman JM, Vining EP · Epilepsia · 1998-05-13

Other

1308. The ketogenic diet: the need for a multidisciplinary approach.

Howrie DL, Kraisinger M, McGhee HW, Crumrine PK, Katyal N · The Annals of pharmacotherapy · 1998-04-09

Clinical trial / intervention

1309. Role of the ketogenic diet in children with intractable seizures.

Tallian KB, Nahata MC, Tsao CY · The Annals of pharmacotherapy · 1998-04-09

Review

1310. The ketogenic diet: a practical guide for caregivers.

Carroll J, Koenigsberger D · Journal of the American Dietetic Association · 1998-03-21

Observational human study

1311. [Ketogenic diet: efficacy and tolerability in childhood intractable epilepsy].

Caraballo R, Trípoli J, Escobal L, Cersósimo R, Tenembaum S, Palacios C, Fejerman N · Revista de neurologia · 1998-04-09

Other

1312. The ketogenic diet revisited.

Berryman MS · Journal of the American Dietetic Association · 1997-10-23

Other

1313. An interdisciplinary team approach to implementing the ketogenic diet for the treatment of seizures.

Batchelor L, Nance J, Short B · Pediatric nursing · 1997-11-14

Other

1314. Use of the ketogenic diet in treating children with seizures.

McDonald ME · Pediatric nursing · 1997-11-14

Case report / case series

1315. A review of the newer antiepileptic drugs and the ketogenic diet.

Barron TF, Hunt SL · Clinical pediatrics · 1997-11-05

Preclinical / mechanistic

1316. Ketogenic diet: effects on expression of kindled seizures and behavior in adult rats.

Hori A, Tandon P, Holmes GL, Stafstrom CE · Epilepsia · 1997-07-01

Review

1317. The ketogenic diet revisited: back to the future.

Nordli DR, De Vivo DC · Epilepsia · 1997-07-01

Other

1318. Spotlight on an old remedy: the ketogenic diet.

Chee CM · Clinical nursing practice in epilepsy · 1997-07-01

Case report / case series

1319. [Drug-resistant epilepsy treated with ketogenic diet].

Tagliabue A, Bertoli S, Trentani C, Lanzola E, Manfredi L, Veggiotti PA, Lanzi G · Recenti progressi in medicina · 1997-02-01

Review

1320. The ketogenic diet: 1997.

Swink TD, Vining EP, Freeman JM · Advances in pediatrics · 1997-01-01

Other

1321. Management of intractable childhood seizures using the non-MCT oil ketogenic diet in 20 patients.

Edelstein SF, Chisholm M · Journal of the American Dietetic Association · 1996-11-01

Other

1322. Rediscovering the benefits of ketogenic diet therapy for children.

Amorde-Spalding K, Woch MA · Journal of the American Dietetic Association · 1996-11-01

Other

1323. Carbohydrate and alcohol content of 200 oral liquid medications for use in patients receiving ketogenic diets.

Feldstein TJ · Pediatrics · 1996-04-01

Review

1324. Alternative epilepsy therapies: the ketogenic diet, immunoglobulins, and steroids.

Prasad AN, Stafstrom CF, Holmes GL · Epilepsia · 1996-01-01

Other

1325. The ketogenic diet: Fa(c)t or fiction.

Wheless JW · Journal of child neurology · 1995-11-01

Randomized clinical trial

1326. Achieving and maintaining compliance with the ketogenic diet.

Amari A, Grace NC, Fisher WW · Journal of applied behavior analysis · 1995-01-01

Other

1327. Ketogenic diet for seizure control.

Fiechtner H · South Dakota journal of medicine · 1995-10-01

Case report / case series

1328. [Effect of the ketogenic diet for West syndrome into which early infantile epileptic encephalopathy with suppression-burst was evolved].

Takusa Y, Ito M, Kobayashi A, Sejima H, Kishi K, Shiraishi H · No to hattatsu = Brain and development · 1995-09-01

Other

1329. Increased very long chain fatty acids in patients on a ketogenic diet: a cause of diagnostic confusion.

Theda C, Woody RC, Naidu S, Moser AB, Moser HW · The Journal of pediatrics · 1993-05-01

Review

1330. Efficacy of the ketogenic diet for intractable seizure disorders: review of 58 cases.

Kinsman SL, Vining EP, Quaskey SA, Mellits D, Freeman JM · Epilepsia · 1992-11-01

Other

1331. Should diet soft drinks be restricted on a ketogenic diet?

Brunetti A · Journal of the American Dietetic Association · 1991-07-01

Other

1332. Urolithiasis associated with the ketogenic diet.

Herzberg GZ, Fivush BA, Kinsman SL, Gearhart JP · The Journal of pediatrics · 1990-11-01

Case report / case series

1333. Use of the traditional ketogenic diet for treatment of intractable epilepsy.

Gasch AT · Journal of the American Dietetic Association · 1990-10-01

Review

1334. [Ketogenic diet--an update].

Gross-Tsur V, Steinberg A, Amir N · Harefuah · 1989-12-15

Case report / case series

1335. Impaired neutrophil function in children with seizures treated with the ketogenic diet.

Woody RC, Steele RW, Knapple WL, Pilkington NS · The Journal of pediatrics · 1989-09-01

Other

1336. [Selected data from childhood epilepsies. ACTH treatment and ketogenic diet: a critical evaluation].

Renier WO, Le Coultre R · Tijdschrift voor kindergeneeskunde · 1989-06-01

Other

1337. Ketogenic diets in the treatment of epilepsy: short-term clinical effects.

Schwartz RH, Eaton J, Bower BD, Aynsley-Green A · Developmental medicine and child neurology · 1989-04-01

Other

1338. Metabolic effects of three ketogenic diets in the treatment of severe epilepsy.

Schwartz RM, Boyes S, Aynsley-Green A · Developmental medicine and child neurology · 1989-04-01

Other

1339. [Evaluation of the effectiveness of the ketogenic diet with medium-chain triglycerides, in the treatment of refractory epilepsy in children. Apropos of a series of cases].

Ros Pérez P, Zamarrón Cuesta I, Aparicio Meix M, Sastre Gallego A · Anales espanoles de pediatria · 1989-03-01

Other

1340. Corn oil ketogenic diet for children with intractable seizures.

Woody RC, Brodie M, Hampton DK, Fiser RH · Journal of child neurology · 1988-01-01

Case report / case series

1341. Therapeutic effects of a ketogenic diet in Rett syndrome.

Haas RH, Rice MA, Trauner DA, Merritt TA · American journal of medical genetics. Supplement · 1986-01-01

Other

1342. Early biochemical and EEG correlates of the ketogenic diet in children with atypical absence epilepsy.

Ross DL, Swaiman KF, Torres F, Hansen J · Pediatric neurology · 1985-03-01

Preclinical / mechanistic

1343. [Effect of ketogenic diet on the convulsive threshold and brain amino acid and monoamine levels in young mice].

Otani K, Yamatodani A, Wada H, Mimaki T, Yabuuchi H · No to hattatsu = Brain and development · 1984-01-01

Preclinical / mechanistic

1344. Fasting and ketogenic diet effects on audiogenic seizures susceptibility of magnesium deficient rats.

Mahoney AW, Hendricks DG, Bernhard N, Sisson DV · Pharmacology, biochemistry, and behavior · 1983-05-01

Preclinical / mechanistic

1345. Effects of ketogenic diet on electroconvulsive threshold and brain contents of adenosine nucleotides.

Nakazawa M, Kodama S, Matsuo T · Brain & development · 1983-01-01

Case report / case series

1346. Diet induced ketosis in epilepsy and anaesthesia. Metabolic changes in three patients on a ketogenic diet.

Hinton W, Schwartz RH, Loach AB · Anaesthesia · 1982-01-01

Review

1347. The ketogenic diet: mechanism of anticonvulsant action.

Withrow CD · Advances in neurology · 1980-01-01

Other

1348. Disordered mineral metabolism produced by ketogenic diet therapy.

Hahn TJ, Halstead LR, DeVivo DC · Calcified tissue international · 1979-08-24

Case report / case series

1349. Optic neuropathy in ketogenic diet.

Hoyt CS, Billson FA · The British journal of ophthalmology · 1979-03-01

Other

1350. Medium chain triglyceride oil ketogenic diets in the treatment of childhood epilepsy.

Clark BJ, House FM · Journal of human nutrition · 1978-04-01

Other

1351. Medium-chain triglycerides in a ketogenic diet.

Stephenson JB, House FM, Stromberg P · Developmental medicine and child neurology · 1977-10-01

Case report / case series

1352. A clinical electroencephalographic correlation of seizures on a ketogenic diet.

Janaki S, Rashid MK, Gulati MS, Jayaram SR, Baruah JK, Saxena VK · The Indian journal of medical research · 1976-07-01

Other

1353. Ketonemia and seizures: metabolic and anticonvulsant effects of two ketogenic diets in childhood epilepsy.

Huttenlocher PR · Pediatric research · 1976-05-01

Other

1354. Letter: Ketogenic diet and epilepsy.

Livingston S, Pauli LL · Developmental medicine and child neurology · 1975-12-01

Other

1355. Letter: The ketogenic diet, West and Lennox syndromes.

Berman W · Developmental medicine and child neurology · 1975-04-01

Preclinical / mechanistic

1356. An animal model for the ketogenic diet.

Appleton DB, DeVivo DC · Epilepsia · 1974-06-01

Other

1357. [Practical suggestions concerning the use of ketogenic diet in treatment of childhood epilepsy].

Czerwińska-Ciechan K, Zablocka I · Neurologia i neurochirurgia polska · 1974-01-01

Other

1358. Ketotic hypoglycemia and the ketogenic diet.

DeVivo DC, Pagliara AS, Prensky AL · Neurology · 1973-06-01

Other

1359. Ketogenic diet containing medium-chain triglycerides.

Signore JM · Journal of the American Dietetic Association · 1973-03-01

Other

1360. An improved ketogenic diet for treatment of epilepsy.

Lasser JL, Brush MK · Journal of the American Dietetic Association · 1973-03-01

Preclinical / mechanistic

1361. An experimental animal model for the effect of ketogenic diet on epilepsy.

Appleton DB, De Vivo DC · Proceedings of the Australian Association of Neurologists · 1973-01-01

Preclinical / mechanistic

1362. Anticonvulsant properties of the ketogenic diet in mice.

Uhlemann ER, Neims AH · The Journal of pharmacology and experimental therapeutics · 1972-02-01

Other

1363. Use of ketogenic diet in epilepsy in childhood.

Hopkins IJ, Lynch BC · Australian paediatric journal · 1970-03-01

Other

1364. Use of the ketogenic diet in epilepsy in childhood.

Hopkins IJ, Lynch BC · Proceedings of the Australian Association of Neurologists · 1970-01-01

Observational human study

1365. Implementation of a ketogenic diet clinic in Mexico: A pilot program in a resource-limited setting.

Chavez-Castillo M, Hurtado-Cuan P, Soto-Blanquel MA, Jimenez-Ruiz A, Gomez-Figueroa E, Marquez-Palacios R · Epilepsy & behavior reports · 2025-12-16

Other

1366. The Role of Carnitine Monitoring and Supplementation in Children With Epilepsy on a Ketogenic Diet.

Vail E, Turner Z, Kossoff EH · Journal of child neurology · 2025-07-23

Clinical trial / intervention

1367. The anti-epileptic mechanism of a ketogenic diet regulating the gut microbiota via SIRT2 activation of the PI3K/AKT signaling pathway.

Li M, Deng H, Ma L, Sun M · Neuroscience letters · 2025-12-09

Other

1368. The ketogenic diet alters microbiome-metabolome profiles to improve West syndrome therapy.

Xie G, Zhou Q, Liao J, Zheng Y, Wang W, Shen K · Pediatric investigation · 2025-11-19

Other

1369. Partial substitution of ketogenic diet therapy with a blended diet: Evaluation of clinical practice in neurologically impaired fully tube fed children.

Guglielmetti M, Verhagen M, van Steenbergen E, van den Berg S, Koudijs S, de Koning B, van der Louw E · Nutrition (Burbank, Los Angeles County, Calif.) · 2025-09-14

Preclinical / mechanistic

1370. The ketogenic diet alleviates neuronal ferroptosis in epilepsy via HDAC4/TFRC signalling.

An W, Xing M, Fan W, Zheng K, Xu X · Archives of medical science : AMS · 2025-07-02

Clinical trial / intervention

1371. Gut microbiota signatures associated with ketogenic diet response in pediatric drug-resistant epilepsy.

Wang Y, Guo J, Zhang P, Zhou Q, Peng K, Xu Z, Dong X, Ye J, Li H · Seizure · 2025-12-23

Randomized clinical trial

1372. Modified atkins diet in children with developmental and epileptic encephalopathy with spike-wave activation in sleep (D/EE-SWAS): A prospective interventional, non-randomized, single-arm study.

Singh S, Saini AG, Puri D, Pattanaik S, Sharma R, Malhi P, Suthar R, Sahu JK, Sankhyan N · Seizure · 2025-11-06

Systematic review / meta-analysis

1373. The utility of ketogenic diet therapy in the management of epileptic spasms: A systematic review and meta-analysis.

Yakemow G, Aleluya S, Ramachandrannair R, Jones KC, Cunningham J, Rodrigues M, Chau V, Sharma S, Jain P, Whitney R · Epilepsy research · 2025-11-15

Observational human study

1374. Motives and predictors of modified Atkins diet discontinuation as treatment of adults with drug-resistant epilepsy.

Samões R, Cavalheiro A, Tavares MM, Teixeira C, Leal B, Chaves J, Cavaco S · Epilepsia · 2025-10-03

Randomized clinical trial

1375. Ketogenic Diet Therapy for Adult Febrile Infection-Related Epilepsy Syndrome (FIRES): A Case Series of Five Patients and Clinical Efficacy Analysis.

Fan M, Li Y, Diao H, Wang Y · Infection and drug resistance · 2025-12-24

Clinical trial / intervention

1376. Development and validation of the iKETO-KNOW questionnaire: A tool for assessing knowledge of the ketogenic diet therapy.

Zanaboni MP, Grumi S, Lopes Neri LC, Pasca L, Geraci MA, Giobbe V, Guglielmetti M, Tagliabue A, Giorgis V, KDTs Delphi Validation Study Group · Epilepsy & behavior : E&B · 2025-10-29

Observational human study

1377. Ketogenic diet therapy enables antiseizure medication reduction and withdrawal in children with epilepsy.

Zinger JW, Rietdijk WJR, van den Berg S, Neuteboom RF, Ruijgrok EJ, van der Louw EJTM, Nijstad AL · Seizure · 2025-10-19

Other

1378. Classic or classical ketogenic diet? Definitions and nomenclature.

RamachandranNair R, Stafstrom CE, Kossoff EH · Epileptic disorders : international epilepsy journal with videotape · 2025-08-29

Clinical trial / intervention

1379. Dietary Management of Eosinophilic Esophagitis in Patients on a Ketogenic Diet for Refractory Epilepsy: A Retrospective Clinician Reported Case Series.

Urbanik K, Prakash V, Pandey A, Jennings R · Nutrients · 2025-11-21

Observational human study

1380. Case Report: Successful multimodal management of FIRES in a pediatric patient using anakinra, ketogenic diet, and induced hypothermia.

Caporale M, Lais G, Gulli' A, Caporale C, Piastra M, Conti G · Frontiers in pediatrics · 2025-11-10

Review

1381. Alteration of Gut Microbiota by Ketogenic Diet as an Alternative Therapeutic Target for Drug-Resistant Epilepsy.

Tang M, Wang W, Wang J, Wang Y · Microorganisms · 2025-11-06

Systematic review / meta-analysis

1382. Efficacy of ketogenic diet therapy for pediatric drug-resistant epilepsy with monogenic etiology: A single-arm meta-analysis.

Jiang A, Liu W, Liu Y, Zhang J · Nutrition reviews · 2025-10-10

Review

1383. Over twenty-five years of ketogenic diet therapy: Supporting children and adults with drug-resistant epilepsy using nutritionally complete ketogenic formulations: A scoping review.

Carroll JH, Simpson Z, Healy L, Szwec C, Hofman DL · Epilepsy & behavior : E&B · 2025-09-08

Systematic review / meta-analysis

1384. The efficacy and safety of the ketogenic diet in infantile epileptic spasm syndrome: a meta-analysis.

Zuo C, Xu K, Ni K, Xiang Y, Wang Y, Liu Z, Sun D · Seizure · 2025-08-25

Preclinical / mechanistic

1385. Hippocampal proteomic signatures of the ketogenic diet in a model of infantile epileptic spasms syndrome.

Campbell JC, Mu C, Ram TR, Young D, Dufour A, Scantlebury MH, Shearer J · Biochimica et biophysica acta. Molecular basis of disease · 2025-08-05

Observational human study

1386. Use of a gradual introduction of a ketogenic diet over 3 weeks for pediatric epilepsy in Mexico.

López-Contreras IN, García-Beristain JC, Villalpando-Carrión S, Cruz-Hernández AM, Vilchis-Gil J, Klünder-Klünder M · Epilepsy & behavior : E&B · 2025-05-31

Clinical trial / intervention

1387. The Influence of the Probiotics, Ketogenic Diets, and Gut Microbiota on Epilepsy and Epileptic Models: A Comprehensive Review.

Shirzadi P, Farokh P, Osouli Meinagh S, Izadi-Jorshari G, Hajikarimloo B, Mohammadi G, Parvardeh S, Nassiri-Asl M · Molecular neurobiology · 2025-05-02

Guideline / consensus

1388. Ketogenic diet for infantile epileptic spasms.

Scantlebury MH, Choudhary A, Ng AC, Gavrilovici C · Epilepsia open · 2025-10-29

Clinical trial / intervention

1389. Development and Validation of a Caregiver-Reported Quality-of-Life Questionnaire for Pediatric Patients With Drug-Resistant Epilepsy on a Ketogenic Diet.

Basu S, Hemamalini AJ, Manokaran RK · Cureus · 2025-10-10

Preclinical / mechanistic

1390. A novel ketogenic diet that reduces seizures and prevents liver steatosis leads to related gut microbiome changes and restores cecal short-chain fatty acid levels in the rapid kindling rat model of epileptogenesis.

Meeusen H, Lohr J, van Eijndthoven T, Kalf RS, Roeselers G, van Helvoort A, Gorter JA, van Vliet EA, Tims S, Silva JP, Aronica E · Gut microbes reports · 2025-10-09

Clinical trial / intervention

1391. Vagus nerve stimulation combined with ketogenic diet versus ketogenic diet alone in the treatment of febrile infection-related epilepsy syndrome in children: efficacy and long-term prognosis study.

Wang T, Chen X, Zhu R, Wang Y, Gong X, Yu L, Wang Y, Zhou Y · Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2025-10-06

Other

1392. The therapeutic effects of ketogenic diet, lacosamide, and combination therapy in children with refractory epilepsy.

Pang Q, Li B, Zhang S, Li J · BMC pediatrics · 2025-10-03

Systematic review / meta-analysis

1393. Classical and Modified Ketogenic Diets for Children and Young People With Drug-Resistant Epilepsy: A Reflection of International Dietetic Practice and Best Practice Recommendations for Dietitians.

Schoeler NE, Whiteley VJ, Guglielmetti M, Neri LCL, Blackford R, Tan-Smith C, Aylward N, Barwick K, Caballero ME, Gudej-Rosa S, Huang WL, Johnson M, Keow COB, Madsen S, Megaw K, Njobvu TN, Pfeifer H, Phillips S, van der Louw E, Best Practice Recommendations Advisory Group, on behalf of the Ketogenic Dietitians Research Network · Journal of human nutrition and dietetics : the official journal of the British Dietetic Association · 2025-09-09

Other

1394. A Case of Wernicke-Korsakoff Encephalopathy in a Child With Refractory Epilepsy on Ketogenic Diet.

Hanson FK, Cermignano S, Petrescu MS, Avula SK · Pediatric neurology · 2025-07-09

Other

1395. Quality assessment of online information on the use of the ketogenic diet in Epilepsy: A comparative analysis of English and Polish sources.

Zakrzewski D, Woźniak JS, Orłowska J, Łukasiński K, Renachowska K, Kitewska W, Kubziakowska W, Sawicka A, Zawadzka M, Mazurkiewicz-Bełdzińska M · Epilepsy & behavior : E&B · 2025-07-25

Other

1396. The nutritional adequacy of the ketogenic diet in paediatric epilepsy: Detailed nutrient analysis and dietary recommendations.

Tsang E, Webster R, Mohammad S, Menezes M, Kothur K, Tantsis E, Troedson C, Gupta S, Gill D, Patel S, Dale RC · Clinical nutrition ESPEN · 2025-07-14

Case report / case series

1397. Solute Carrier 45A1: A New Cerebral Glucose Transporter Brain Disorder with Focal Refractory Epilepsy Responsive to Ketogenic Diet and Acetazolamide.

Semal B, Neuens S, Vilain C, De Laet C, Leurquin-Sterk G, Sculier C, Baijot S, Aeby A · Neuropediatrics · 2025-06-04

Observational human study

1398. An international survey on withdrawing the ketogenic diet therapy for epilepsy.

Donnard N, Höhn S, Devlin AM, Kossoff EH, Schoeler NE, van der Louw E, Rho JM, Dozières-Puyravel B, Auvin S · Epilepsy & behavior : E&B · 2025-05-28

Preclinical / mechanistic

1399. Neurochemical and genetic effects of the ketogenic diet: alterations in brain GABA, glutamate, and related gene.

Ebrahimi Behnam B, Raeisi S, Bakhtiari N, Abbasi MM, Shanehbandi D · Molecular biology reports · 2025-09-30

Observational human study

1400. The effectiveness of the ketogenic diet in treating refractory epilepsy: A study of different seizure forms.

Wang M, Zhang H, Tian P, Hu W, Chen Y · Medicine · 2025-05-29

Review

1401. The Ketogenic Diet Through a Metabolomic Lens: Biochemical Pathways, Therapeutic Applications, and Analytical Challenges.

Idzikowska K, Gątarek P, Gajda A, Safiński P, Przyslo L, Kałużna-Czaplińska J · Nutrients · 2025-09-16

Systematic review / meta-analysis

1402. Impact of a high-fat, low-carbohydrate ketogenic diet on seizure frequency in children with drug-resistant epilepsy: a systematic review and Meta-analysis.

Liu J, E RH, Zhang JQ, Wang DP · Frontiers in nutrition · 2025-09-10

Other

1403. Deepening the understanding of mechanisms of antiepileptic effects of the ketogenic diet in children with AFG2A-related encephalopathy.

Catsman-Berrevoets C · European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society · 2025-08-18

Randomized clinical trial

1404. Modified Atkins diet versus topiramate in young children with epileptic spasms refractory to steroids and vigabatrin: a randomised open-label trial.

Meena R, Roy Chowdhury S, Elwadhi A, Jain P, Mukherjee SB, Sharma S · Seizure · 2025-08-10

Systematic review / meta-analysis

1405. Short and long-term side effects of the Classic Ketogenic Diet in pediatric epilepsy treatment: A systematic review of clinical trials.

Sepehrar S, Sadeghi T, Kossoff E, Nikoonia M, Zarei M, Toosi MB, Talebi S · Seizure · 2025-08-07

Preclinical / mechanistic

1406. AFG2A-related encephalopathy: Effectiveness of ketogenic diet in epilepsy and mitochondrial dynamics modulation.

Nou-Fontanet L, Musokhranova U, Camacho AR, Chilavert VD, Insuga VS, Fernández LA, Alonso-Colmenero I, Arzimanoglou A, Cazorla ÁG, Oyarzabal A, Fons C · European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society · 2025-07-19

Review

1407. Ketogenic Diet for Epilepsy: The Olive Oil Effect to Optimization. A Narrative Review.

Zouganeli S, Yannakoulia M, Attilakos A, Fessatou S, Mitsou EK, Kyriacou A, Dinopoulos A · Journal of medicinal food · 2025-07-02

Clinical trial / intervention

1408. Neural dynamics remodeling induced by ketogenic diet therapy in drug-resistant epilepsy: A functional magnetic resonance imaging study.

Li H, Shao X, He F, He C, Yang Y, Ge Y, Chen R, Wang Z, Gong Y, Long X, Miao P, Ding Y, Wang S, Zhang M · Epilepsia · 2025-06-04

Randomized clinical trial

1409. Beyond epilepsy management: A narrative review of the health effects of ketogenic diets.

Chamma L, Chamma N, Mattar L, Slaybe M, Haidar S, Rizk R · Nutrition (Burbank, Los Angeles County, Calif.) · 2025-04-16

Clinical trial / intervention

1410. Fecal Metaproteomics as a Tool to Monitor Functional Modifications Induced in the Gut Microbiota by Ketogenic Diet: A Case Study.

Tanca A, Masia S, Giustacchini P, Uzzau S · Proteomics · 2025-01-05

Review

1411. Drugs and Nutrients in Epilepsy: Vitamin B6 and the Ketogenic Diet.

Bahalul-Yarchi S, Hartman F, Ben Zaken K, Sawaid IO, Segev L, Mesfin S, Frankel P, Ezzy R, Samson AO · Nutrients · 2025-08-19

Clinical trial / intervention

1412. Progress of ketogenic diet in the treatment of developmental epileptic encephalopathy.

Hu W, Li L, Zhao F, Zhang H, Zhang H · Frontiers in pediatrics · 2025-08-04

Observational human study

1413. Kenyan dietitians' knowledge of ketogenic dietary therapies for drug-resistant epilepsy.

Samia P, Naanyu V, Ndila P, Cross JH, Idro R, Boon P, Wilmshurst JM, Luchters S · BMC nutrition · 2025-08-02

Randomized clinical trial

1414. Safety, Efficacy, and Tolerability of Ketogenic Diet Versus Adrenocorticotropic Hormone in Infantile Epileptic Spasms Syndrome: A Randomized Controlled Trial.

Mahesan A, Gulati S, Sondhi V, Agarwala A, Gupta KL, Kamila G, Jauhari P, Chakrabarty B, Pandey RM · Pediatric neurology · 2025-06-03

Observational human study

1415. Confirmatory study on the retention rate of ketogenic diet therapy and related factors in children with drug-resistant epilepsy: A single-center cohort study.

Zhang J, Gu Q, Wu Y, Xie H, Wei C, Zhang Y, Ji T, Bao X, Chang X, Zhang Y, Jiang Y, Wu Y · Epilepsia open · 2025-06-19

Observational human study

1416. Outcomes of Ketogenic Diet in Pediatric Intractable Epilepsy and Neurometabolic Disorders: Insights From the First Iranian Registry.

Karimzadeh P, Kachuei M, Eghdami S, Beglar MB, Azizi M · Pediatric neurology · 2025-05-16

Guideline / consensus

1417. Ketogenic diet therapy for epilepsy during pregnancy and lactation: An international survey exploring clinician perspectives.

Faltersack K, McDonald TJW, De Giorgis V, Barron B, Cervenka MC, Devlin A, Healy LA, Kverneland M, van der Louw E, Lu M, Zanaboni MP, Armeno M, Felton EA · Epilepsia open · 2025-05-29

Observational human study

1418. A retrospective analysis of pediatric patients on a ketogenic diet: A comparison of inpatient versus outpatient diet initiations.

Stillman C, Knupp K, Oliver J, Conley A, Kennedy K, Silveira L, Joshi C · Epilepsy research · 2025-04-29

Observational human study

1419. The Ketogenic Diet: An Underrecognized Therapy for Rett Syndrome.

Haridas B, Bessone S, Turner Z, Kossoff E · Journal of child neurology · 2025-04-10

Observational human study

1420. Impact of modified Atkins diet on growth in infants and children with epilepsy.

Chang J, Schimpf S, Phitsanuwong C · Epileptic disorders : international epilepsy journal with videotape · 2025-02-19

Other

1421. A primary mechanism for efficacy of the ketogenic diet may be energy repletion at the tripartite synapse.

Joshi SN, Joshi AN, Joshi ND · Journal of neural engineering · 2025-07-24

Case report / case series

1422. A novel mutation in the DYNC1H1 gene causing developmental and epileptic encephalopathy treated with ketogenic diet: A case report.

Zhao F, Sun L, Hu W, Zhang H · Medicine · 2025-07-15

Clinical trial / intervention

1423. Unlocking Hope: Development of India's First Indigenous Ketogenic Dietary Formula for Pediatric Epilepsy Care.

Basu S, Hemamalini AJ · Annals of Indian Academy of Neurology · 2025-06-09

Other

1424. Intractable epilepsy in m.1630A>G carriers should be treated with a ketogenic diet on a trial basis.

Finsterer J · Translational pediatrics · 2025-06-25

Case report / case series

1425. Perioperative management of scoliosis surgery in child with epilepsy on the ketogenic diet: Case report.

Yang F, Hou D, Wen J · Medicine · 2025-07-01

Preclinical / mechanistic

1426. Protective Effects of the Ketogenic Diet on Cognitive Impairment Induced by Status Epilepticus in Rats: Modulation of Neuroinflammation Through the NF-κB Signaling Pathway.

Wang W, Wang L, Jiang C, Zhang S, Tan C, Peng L, Ding R, Tian B, Song X, Jiang L · Pediatric discovery · 2025-06-23

Randomized clinical trial

1427. Role of the Ketogenic Diet Therapy and ACTH as Second Treatments in Drug-Resistant Infantile Epileptic Spasms Syndrome.

Dressler A, Bonfanti L, Trimmel-Schwahofer P, Porsche B, Bertoli S, Male C · Nutrients · 2025-06-23

Preclinical / mechanistic

1428. Ketogenic diet dampens excitatory neurotransmission by shrinking synaptic vesicle pools.

Stunault MI, Deng P, Periandri EM, Vitorino FN, Barfield AJ, Ponce RJ, Garcia BA, Egervari G, Klyachko VA, Ashrafi G · bioRxiv : the preprint server for biology · 2025-06-07

Preclinical / mechanistic

1429. Author Correction: Dietary fiber content in clinical ketogenic diets modifies the gut microbiome and seizure resistance in mice.

Özcan E, Yu KB, Dinh L, Lum GR, Lau K, Hsu J, Arino M, Paramo J, Lopez-Romero A, Hsiao EY · Nature communications · 2025-06-02

Clinical trial / intervention

1430. Knowledge, attitudes, and practices of epilepsy patients regarding the ketogenic diet therapy: A cross-sectional study.

Zhang X, Sun M, Xue G, Zhao Y, Du T, Guan X, Xu Y · Epilepsia open · 2025-05-05

Other

1431. Addressing the long-term growth impact of the modified Atkins diet in pediatric epilepsy: A call for further research.

Wang SJ, Wei LC · Epileptic disorders : international epilepsy journal with videotape · 2025-04-04

Observational human study

1432. Association of node assortativity and internalizing symptoms with ketogenic diet effectiveness in pediatric patients with drug-resistant epilepsy.

Chen YF, Lin WC, Yu Su T, Hsieh TY, Hung KY, Hsu MH, Lin YJ, Kuo HC, Hung PL · Nutrition (Burbank, Los Angeles County, Calif.) · 2025-02-25

Preclinical / mechanistic

1433. In Preclinical Epilepsy, GLUT1 and GFAP Dysregulation in Cells Surrounding the Third Ventricle, Including Tanycytes, Is Differentially Restored with Ketogenic Diet Treatment.

Rafiei P, Mian HS, Iyer SH, Draves SB, Matthews SA, Rendon DE, Neesen EJ, Dunlay M, Revis M, Glisan AL, Simeone TA, Simeone KA · Nutrients · 2025-05-28

Observational human study

1434. Prescribing errors in hospitalized patients on the ketogenic diet.

Yen CY, Kronisch L, Whitley K, Carew B, Zaldana A, Diaz-Medina G, Katyayan A, Cokley JA · American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists · 2025-05-26

Other

1435. Immediate inpatient carbohydrate challenge: Novel method of ketogenic diet therapy discontinuation.

Kossoff EH, Turner Z · Epilepsia · 2025-03-06

Randomized clinical trial

1436. Comparison of efficacy of low glycemic index treatment and modified Atkins diet among children with drug-resistant epilepsy: A randomized non-inferiority trial.

Anand V, Gulati S, Agarwala A, Kamila G, Mahesan A, Sondhi V, Gupta KL, Chakrabarty B, Jauhari P, Panda PK, Pandey RM · Epilepsia · 2025-01-30

Systematic review / meta-analysis

1437. Database Analysis of Application Areas and Global Trends in Ketogenic Diets from 2019 to 2024.

Assmann M, Albrecht I, Frenser M, Marquardt T, Fischer T · Nutrients · 2025-04-27

Other

1438. Telemedicine for Ketogenic Dietary Treatment in Epilepsy and Inherited Metabolic Diseases: Survey of Health Care Professionals.

Höller A, Schönlaub AK, Uhlisch C, Klingler P, Welte S, Pfeifer B, Schreier G, Scholl-Bürgi S, Male-Dressler A · Studies in health technology and informatics · 2025-04-24

Observational human study

1439. Genetic aetiologies in relation to response to the ketogenic diet in 226 children with epilepsy.

Dahlin M, Stödberg T, Ekman E, Töhönen V, Wedell A · Brain communications · 2025-04-05

Observational human study

1440. Exploring the effect of valproic acid levels on patients with epilepsy treated with ketogenic diet: An observational study.

Tarrant S, Liubauske A, Zhu G, Zhang B, Pfeifer H, Paris A, Bergin AM, Pinto AL · Epilepsia open · 2025-02-27

Clinical trial / intervention

1441. Barriers and facilitators to starting and staying on ketogenic diet therapy for children with epilepsy: A scoping review.

Hameed H, Lopes Neri LC, Schoeler N · Clinical nutrition ESPEN · 2025-02-22

Randomized clinical trial

1442. The impact of ketogenic diet on the frequency of psychogenic non-epileptic seizures (PNES): A feasibility randomized pilot study.

Janssen-Aguilar R, la Portilla JG, Martínez-Juárez IE, Mimiaga-Hernandez C, Alvarado-Luis G, Aguilar-Hernandez A, Garcia-Esparza KA, Hernadez-Palestina M, Crail-Meléndez D · Epilepsia open · 2025-01-22

Clinical trial / intervention

1443. From Hesitation to Confidence: Shifting Parental Attitude and Perception Toward Ketogenic Diet in Treating Children With Drug-Resistant Epilepsy.

Basu S, Hemamalini AJ, Manokaran RK · Cureus · 2025-03-29

Clinical trial / intervention

1444. Clinical Efficacy and Safety of the Ketogenic Diet in Patients with Genetic Confirmation of Drug-Resistant Epilepsy.

Na JH, Lee H, Lee YM · Nutrients · 2025-03-11

Clinical trial / intervention

1445. Cognitive and behavioral impact of antiseizure medications, neuromodulation, ketogenic diet, and surgery in Lennox-Gastaut syndrome: A comprehensive review.

Samanta D · Epilepsy & behavior : E&B · 2025-01-23

Other

1446. Exploring physiological beta-hydroxybutyrate level in children treated with the classical ketogenic diet for drug-resistant epilepsy.

Qiao X, Ye Z, Wen J, Lin S, Cao D, Chen L, Zou D, Zou H, Zhang M, Chen Z, Kwan P, Scheffer IE, Qin J, Liao J · Acta epileptologica · 2025-02-07

Review

1447. Application and Mechanism of Action of a Ketogenic Diet in Antiepileptic Therapy.

Zhou C, Qu S · ACS chemical neuroscience · 2025-01-09

Systematic review / meta-analysis

1448. Illuminating the Safety, Tolerability, and Efficacy of Different Ketogenic Diets for Individuals with Epilepsy: A Scoping Meta-Review.

Abbasi MM, Jafari A, Mohtadi M, Shahabi M, Bakhshimoghaddam F, Abbasi H, Eslamian G · Seizure · 2025-01-17

Randomized clinical trial

1449. Decanoic acid-enriched ketogenic diet in refractory epilepsy.

Shin HJ, Ryu S, Lee N, Lee E, Ko A, Kang HC, Lee JS, Kim SH, Kim HD · Frontiers in neurology · 2025-01-27

Observational human study

1450. Breaking Myths: The Underexplored Impact of the Ketogenic Diet on Managing Drug-Resistant Epilepsy in Infancy.

Basu S, Arambakkam Janardhanam H, Manokaran RK · Cureus · 2025-01-22

Observational human study

1451. Characterizing the fecal microbiome in patients on the ketogenic diet for drug resistant epilepsy.

Freibauer A, Pai N, RamachandranNair R · Heliyon · 2025-01-02

Review

1452. Potential inflammatory mechanisms of the ketogenic diet against febrile infection-related epilepsy syndrome.

Wang J, Xie L, Jiang L · Acta epileptologica · 2025-01-10

Review

1453. Impact of the Ketogenic Diet on Neurological Diseases: A Review.

Rubio C, López-Landa A, Romo-Parra H, Rubio-Osornio M · Life (Basel, Switzerland) · 2025-01-09

Observational human study

1454. [Ketogenic diet therapy in adolescents and adults with drug resistant epilepsy. Experience in Uruguay].

Avellanal A, Vique N, Scaramelli A · Medicina · 2025-11-28

Observational human study

1455. Harmful metabolic acidosis in children treated by ketogenic diet during prolonged general anesthesia for epilepsy surgery: A single center experience.

Checri R, Gras S, Clariot S, Chivet A, Dangles MT, Bonheur J, Dorison N, Chipaux M, Trouiller P, Ferrand-Sorbets S, Devys JM, Raffo E · European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society · 2025-01-28

Other

1456. Ketogenic Diets for Epileptics.

Pulford DS · California and western medicine · 1927-07-01

Other

1457. Epilepsy in Children: With Particular Reference to the Ketogenic Diet.

Cooder HR · California and western medicine · 1933-09-01

Other

1458. [The treatment of petit Epilepsy With Tridione (Absentol, Petidion) and With Ketogenic Diet].

KLOEK J, LEDEBOER BC · Nederlands tijdschrift voor geneeskunde · 1948-02-14

Other

1459. The ketogenic diet in the treatment of epilepsy in children.

LIVINGSTON S · Postgraduate medicine · 1951-10-01

Other

1460. Practical guide and dietary management of children with seizures using the ketogenic diet.

Mike EM · The American journal of clinical nutrition · 1965-12-01

Other

1461. ACID-BASE, ELECTROLYTE, AND AMINO-ACID METABOLISM IN CHILDREN WITH PETIT MAL. ETIOLOGIC SIGNIFICANCE AND MODIFICATION BY ANTICONVULSANT DRUGS AND THE KETOGENIC DIET.

MILLICHAP JG, JONES JD · Epilepsia · 1964-09-01

Other

1462. MECHANISM OF ANTICONVULSANT ACTION OF KETOGENIC DIET. STUDIES IN ANIMALS WITH EXPERIMENTAL SEIZURES AND IN CHILDREN WITH PETIT MAL EPILEPSY.

MILLICHAP JG, JONES JD, RUDIS BP · American journal of diseases of children (1960) · 1964-06-01

Alzheimer’s Disease Recent peer-reviewed literature

Source-audited references from the connected PDF archive. Only papers directly relevant to this topic and ketogenic therapy/ketosis are shown.

1. Ketogenic diet regulates Uch-L1(C) to improve cerebral energy metabolism and cognitive function in Alzheimer's disease mice

Bibliographic record reviewed for inclusion in the curated Scientific Library.

2. A ketogenic diet improves memory in females in the APOE4 mouse model of Alzheimer’s disease

Bibliographic record reviewed for inclusion in the curated Scientific Library.

3. Consuming a modified Mediterranean ketogenic diet reverses the peripheral lipid signature of Alzheimer’s disease in humans

Bibliographic record reviewed for inclusion in the curated Scientific Library.

4. Serum and CSF metabolomics analysis shows Mediterranean Ketogenic Diet mitigates risk factors of Alzheimer’s disease

Bibliographic record reviewed for inclusion in the curated Scientific Library.

5. Ketogenic diet and BHB rescue the fall of long-term potentiation in an Alzheimer’s mouse model and stimulate synaptic plasticity pathway enzymes

Bibliographic record reviewed for inclusion in the curated Scientific Library.

6. A Potential Role for the Ketogenic Diet in Alzheimer’s Disease Treatment

Bibliographic record reviewed for inclusion in the curated Scientific Library.

7. A Modified Mediterranean Ketogenic Diet mitigates modifiable risk factors of Alzheimer’s disease

Bibliographic record reviewed for inclusion in the curated Scientific Library.

8. Ketone bodies mediate alterations in brain energy metabolism and biomarkers of Alzheimer's disease

Bibliographic record reviewed for inclusion in the curated Scientific Library.

9. Effects of a ketogenic and low-fat diet on the human metabolome, microbiome, and foodome in adults at risk for Alzheimer's disease

Bibliographic record reviewed for inclusion in the curated Scientific Library.

10. Ketogenic interventions in mild cognitive impairment, Alzheimer's disease, and Parkinson's disease: a systematic review and critical appraisal

Bibliographic record reviewed for inclusion in the curated Scientific Library.

11. Case report: Ketogenic diet acutely improves cognitive function in patient with Down syndrome and Alzheimer’s disease

Bibliographic record reviewed for inclusion in the curated Scientific Library.

12. Ketogenic diet prevents chronic sleep deprivation-induced Alzheimer’s disease by inhibiting iron dyshomeostasis and promoting repair via Sirt1/Nrf2 pathway

Bibliographic record reviewed for inclusion in the curated Scientific Library.

13. Potential for Ketotherapies as Amyloid-Regulating Treatment in Individuals at Risk for Alzheimer’s Disease

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Human clinical evidence · 2026

14. The Effect of Simultaneous Application of a Plant-Rich Ketogenic Diet in Alzheimer’s Disease

Original publication title: The Effect of Simultaneous Application of a Plant-Rich Ketogenic Diet in Alzheimer’s Disease

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Preclinical mechanistic study · 2026

15. Ketogenic Diet Regulates UCH-L1 to Improve Cerebral Energy Metabolism and Cognitive Function in Alzheimer's Disease Mice

Original publication title: Ketogenic Diet Regulates UCH-L1 to Improve Cerebral Energy Metabolism and Cognitive Function in Alzheimer's Disease Mice

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Human mechanistic study · 2024

16. A Modified Mediterranean-Style Diet Enhances Brain Function via Specific Gut-Microbiome-Brain Mechanisms

Original publication title: A Modified Mediterranean-Style Diet Enhances Brain Function via Specific Gut-Microbiome-Brain Mechanisms

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Preclinical mechanistic study · 2024

17. Ketogenic Diet and β-Hydroxybutyrate Rescue Long-Term Potentiation in an Alzheimer’s Mouse Model and Stimulate Synaptic Plasticity Pathways

Original publication title: Ketogenic Diet and β-Hydroxybutyrate Rescue Long-Term Potentiation in an Alzheimer’s Mouse Model and Stimulate Synaptic Plasticity Pathways

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Case report · 2023

18. Case Report: Ketogenic Diet Acutely Improves Cognitive Function in a Patient with Down Syndrome and Alzheimer’s Disease

Original publication title: Case Report: Ketogenic Diet Acutely Improves Cognitive Function in a Patient with Down Syndrome and Alzheimer’s Disease

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Preclinical mechanistic study

19. Ketogenic Diet Prevents Chronic Sleep Deprivation-Induced Alzheimer’s Disease by Inhibiting Iron Dyshomeostasis and Promoting Repair via the SIRT1/NRF2 Pathway

Original publication title: Ketogenic Diet Prevents Chronic Sleep Deprivation-Induced Alzheimer’s Disease by Inhibiting Iron Dyshomeostasis and Promoting Repair via the SIRT1/NRF2 Pathway

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Mini-review

20. Efficacy and Safety of Ketone Supplementation or Ketogenic Diets for Alzheimer's Disease: A Mini Review

Original publication title: Efficacy and Safety of Ketone Supplementation or Ketogenic Diets for Alzheimer's Disease: A Mini Review

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Systematic review / meta-analysis

21. Effects of ketogenic diet on cognitive impairment in older adults: a systematic review and meta-analysis.

Xi L, Wan J, Hua Y, Guo M, Du J, Luo X, Yu H · Archives of gerontology and geriatrics · 2026-09-12

Randomized clinical trial

22. The effect of simultaneous application of plant-rich ketogenic diet and intermittent fasting on early-to-mid-stage Alzheimer's disease: a randomised controlled trial.

Tağraf B, Kaygusuz D, Yerlikaya D, Oğul ÖE, Hanoğlu L · The journal of nutrition, health & aging · 2026-07-24

Clinical trial / intervention

23. The Ketogenic Diet: A Possible Intervention for Improving Hippocampal Function in Neurological Disorders.

Jahanmehr D, Ahmadi A, Fadaei M, Sangi Nasab Lahijan A, Shafiee Sabet M, Kalantari Dehaghi H, Asadi-Golshan R · Nutrition reviews · 2026-07-10

Review

24. Ketogenic diet as a therapeutic strategy for neurodegenerative diseases: from mechanisms to translational challenges.

Salgueiro AM, Ferreira-Marques M, Ribeiro RFN, Lopes SM, Pereira D, Costa DG, Santana MM, de Almeida LP, Cavadas C · Translational neurodegeneration · 2026-05-25

Clinical trial / intervention

25. Ketogenic diet enhances cognitive-behavioral function and hippocampal neurogenesis while attenuating amyloid pathology in Tg-SwDI mice.

Pulido-Correa VE, Hernandez AV, Wind EJ, Zhu Y, Vogel C, Binu S, Jeneske M, Kuni D, Chiduruppa V, Echeverria B, Rosenberg L, Robison LS · Journal of Alzheimer's disease : JAD · 2026-05-04

Preclinical / mechanistic

26. Ketogenic diet regulates Uch-L1(C) to improve cerebral energy metabolism and cognitive function in Alzheimer's disease mice.

Bao N, Zhang M, Tang M, Shen Z, Wang S, Jiang G · European journal of histochemistry : EJH · 2026-04-20

Other

27. Mediterranean, MIND, and ketogenic diets in Alzheimer's disease: mechanistic coherence and clinical uncertainty.

Christimann GM, Sattler JAG, Fabi JP · Frontiers in nutrition · 2026-04-15

Other

28. Author Correction: Consuming a modified Mediterranean ketogenic diet reverses the peripheral lipid signature of Alzheimer's disease in humans.

Neth BJ, Huynh K, Giles C, Wang T, Mellett NA, Duong T, Blach C, Schimmel L, Register TC, Blennow K, Zetterberg H, Batra R, Schweickart A, Dilmore AH, Martino C, Arnold M, Krumsiek J, Han X, Dorrestein PC, Knight R, Meikle PJ, Craft S, Kaddurah-Daouk R · Communications medicine · 2026-04-06

Clinical trial / intervention

29. From Refractory Epilepsy to Neurodegeneration: Emerging Mechanistic and Clinical Insights Into the Ketogenic Diet.

Ahire C, Yadav R, Bhamare UU, Kaur G, Palkar MB · FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026-01-25

Preclinical / mechanistic

30. A ketogenic diet improves memory in females in the APOE4 mouse model of Alzheimer's disease.

Di Lucente J, Rutkowsky JM, Errico Provenzano A, Persico G, Zhou Z, Jin LW, Ramsey JJ, Montgomery CB, Kim K, Giorgio M, Maezawa I, Cortopassi GA · GeroScience · 2025-11-24

Clinical trial / intervention

31. Ketogenic β-hydroxybutyrate regulates β-hydroxybutyrylation of TCA cycle-associated enzymes and attenuates disease-associated pathologies in Alzheimer's mice.

Han W, Zhang B, Zhao W, Zhao W, He J, Qiu X, Zhang L, Wang X, Wang Y, Lu H, Zhang Y, Xie Y, Geng Y, Zhao W, Huang Q, Zhang YW, Wang Z · Aging cell · 2024-10-16

Randomized clinical trial

32. Addressing Pain Using a Mediterranean Ketogenic Nutrition Program in Older Adults with Mild Cognitive Impairment.

Klejc K, Cruz-Almeida Y, Sheffler JL · Journal of pain research · 2024-05-23

Randomized clinical trial

33. A randomized feasibility trial of the modified Atkins diet in older adults with mild cognitive impairment due to Alzheimer's disease.

Buchholz A, Deme P, Betz JF, Brandt J, Haughey N, Cervenka MC · Frontiers in endocrinology · 2024-03-04

Review

34. Role of ketogenic diet in neurodegenerative diseases focusing on Alzheimer diseases: The guardian angle.

Al-Kuraishy HM, Jabir MS, Albuhadily AK, Al-Gareeb AI, Jawad SF, Swelum AA, Hadi NR · Ageing research reviews · 2024-02-14

Clinical trial / intervention

35. Ketogenic Approaches for the Treatment of Alzheimer's Disease.

Gabuzyan R, Lee C, Nygaard HB · Journal of Alzheimer's disease : JAD · 2024-10-18

Clinical trial / intervention

36. Intermittent fasting and Alzheimer's disease-Targeting ketone bodies as a potential strategy for brain energy rescue.

Ye YC, Chai SF, Li XR, Wu MN, Cai HY, Wang ZJ · Metabolic brain disease · 2023-10-12

Review

37. A Potential Role for the Ketogenic Diet in Alzheimer's Disease Treatment: Exploring Pre-Clinical and Clinical Evidence.

Oliveira TPD, Morais ALB, Dos Reis PLB, Palotás A, Vieira LB · Metabolites · 2023-12-29

Clinical trial / intervention

38. Ketogenic therapies in Parkinson's disease, Alzheimer's disease, and mild cognitive impairment: An integrative review.

Price S, Ruppar TM · Applied nursing research : ANR · 2023-10-28

Other

39. A Modified Mediterranean Ketogenic Diet mitigates modifiable risk factors of Alzheimer's Disease: a serum and CSF-based metabolic analysis.

Schweickart A, Batra R, Neth BJ, Martino C, Shenhav L, Zhang AR, Shi P, Karu N, Huynh K, Meikle PJ, Schimmel L, Dilmore AH, Blennow K, Zetterberg H, Blach C, Dorrestein PC, Knight R, Alzheimer’s Gut Microbiome Project Consortium, Craft S, Kaddurah-Daouk R, Krumsiek J · medRxiv : the preprint server for health sciences · 2023-11-27

Other

40. Bibliometric analysis of global research profile on ketogenic diet therapies in neurological diseases: Beneficial diet therapies deserve more attention.

Wang Y, Zhang J, Zhang Y, Yao J · Frontiers in endocrinology · 2023-01-04

Clinical trial / intervention

41. [Beneficial effects of ketogenic diet for Alzheimer's disease management].

Charlot A, Lernould A, Plus I, Zoll J · Biologie aujourd'hui · 2023-11-29

Clinical trial / intervention

42. Ketogenic Diet as a Promising Non-Drug Intervention for Alzheimer's Disease: Mechanisms and Clinical Implications.

Xu Y, Zheng F, Zhong Q, Zhu Y · Journal of Alzheimer's disease : JAD · 2023-04-25

Randomized clinical trial

43. Small extracellular vesicles in plasma reveal molecular effects of modified Mediterranean-ketogenic diet in participants with mild cognitive impairment.

Kumar A, Sharma M, Su Y, Singh S, Hsu FC, Neth BJ, Register TC, Blennow K, Zetterberg H, Craft S, Deep G · Brain communications · 2022-10-19

Other

44. Changes in Adiposity and Cerebrospinal Fluid Biomarkers Following a Modified Mediterranean Ketogenic Diet in Older Adults at Risk for Alzheimer's Disease.

Brinkley TE, Leng I, Register TC, Neth BJ, Zetterberg H, Blennow K, Craft S · Frontiers in neuroscience · 2022-06-02

Clinical trial / intervention

45. Ketogenic diet ameliorates cognitive impairment and neuroinflammation in a mouse model of Alzheimer's disease.

Xu Y, Jiang C, Wu J, Liu P, Deng X, Zhang Y, Peng B, Zhu Y · CNS neuroscience & therapeutics · 2021-12-10

Randomized clinical trial

46. The Ketogenic Diet and Alzheimer's Disease.

Hersant H, Grossberg G · The journal of nutrition, health & aging · 2022-06-19

Review

47. A narrative review on the effects of a ketogenic diet on patients with Alzheimer's disease.

Tabaie EA, Reddy AJ, Brahmbhatt H · AIMS public health · 2021-12-22

Review

48. Ketogenic Diet: A Promising Neuroprotective Composition for Managing Alzheimer's Diseases and its Pathological Mechanisms.

Sridharan B, Lee MJ · Current molecular medicine · 2021-04-06

Randomized clinical trial

49. A ketogenic supplement improves white matter energy supply and processing speed in mild cognitive impairment.

Roy M, Fortier M, Rheault F, Edde M, Croteau E, Castellano CA, Langlois F, St-Pierre V, Cuenoud B, Bocti C, Fulop T, Descoteaux M, Cunnane SC · Alzheimer's & dementia (New York, N. Y.) · 2021-11-17

Review

50. Alzheimer's Disease and Type 2 Diabetes Mellitus: The Use of MCT Oil and a Ketogenic Diet.

Takeishi J, Tatewaki Y, Nakase T, Takano Y, Tomita N, Yamamoto S, Mutoh T, Taki Y · International journal of molecular sciences · 2021-11-15

Systematic review / meta-analysis

51. The Efficacy of Ketogenic Therapies in the Clinical Management of People with Neurodegenerative Disease: A Systematic Review.

Dewsbury LS, Lim CK, Steiner GZ · Advances in nutrition (Bethesda, Md.) · 2020-08-24

Other

52. Food for thought: the emerging role of a ketogenic diet in Alzheimer's disease management.

Włodarek D · Expert review of neurotherapeutics · 2021-07-12

Clinical trial / intervention

53. Ketogenic diet therapy in Alzheimer's disease: an updated review.

Lilamand M, Mouton-Liger F, Paquet C · Current opinion in clinical nutrition and metabolic care · 2021-04-20

Clinical trial / intervention

54. The possibility of use of the ketogenic diet and medium chain triglycerides supplementation in the support therapy of Alzheimer disease.

Włodarek D · Current opinion in clinical nutrition and metabolic care · 2021-03-21

Randomized clinical trial

55. Randomized crossover trial of a modified ketogenic diet in Alzheimer's disease.

Phillips MCL, Deprez LM, Mortimer GMN, Murtagh DKJ, McCoy S, Mylchreest R, Gilbertson LJ, Clark KM, Simpson PV, McManus EJ, Oh JE, Yadavaraj S, King VM, Pillai A, Romero-Ferrando B, Brinkhuis M, Copeland BM, Samad S, Liao S, Schepel JAC · Alzheimer's research & therapy · 2021-02-23

Review

56. Emerging Therapeutic Promise of Ketogenic Diet to Attenuate Neuropathological Alterations in Alzheimer's Disease.

Uddin MS, Kabir MT, Tewari D, Al Mamun A, Barreto GE, Bungau SG, Bin-Jumah MN, Abdel-Daim MM, Ashraf GM · Molecular neurobiology · 2020-08-20

Systematic review / meta-analysis

57. To Keto or Not to Keto? A Systematic Review of Randomized Controlled Trials Assessing the Effects of Ketogenic Therapy on Alzheimer Disease.

Grammatikopoulou MG, Goulis DG, Gkiouras K, Theodoridis X, Gkouskou KK, Evangeliou A, Dardiotis E, Bogdanos DP · Advances in nutrition (Bethesda, Md.) · 2019-12-26

Preclinical / mechanistic

58. Ketone production by ketogenic diet and by intermittent fasting has different effects on the gut microbiota and disease progression in an Alzheimer's disease rat model.

Park S, Zhang T, Wu X, Yi Qiu J · Journal of clinical biochemistry and nutrition · 2020-03-20

Clinical trial / intervention

59. Nutritional Ketosis and photobiomodulation remediate mitochondria warding off Alzheimer's disease in a diabetic, ApoE4+ patient with mild cognitive impairment: A case report.

Horner S, Berger L, Gibas K · Photodiagnosis and photodynamic therapy · 2020-04-16

Other

60. To treat or not to treat Alzheimer's disease by the ketogenic diet? That is the question.

Ulamek-Koziol M, Pluta R · Neural regeneration research · 2019-11-14

Systematic review / meta-analysis

61. Are ketogenic diets promising for Alzheimer's disease? A translational review.

Lilamand M, Porte B, Cognat E, Hugon J, Mouton-Liger F, Paquet C · Alzheimer's research & therapy · 2020-04-14

Preclinical / mechanistic

62. A Dietary Ketone Ester Normalizes Abnormal Behavior in a Mouse Model of Alzheimer's Disease.

Pawlosky RJ, Kashiwaya Y, King MT, Veech RL · International journal of molecular sciences · 2020-02-04

Clinical trial / intervention

63. Modified ketogenic diet is associated with improved cerebrospinal fluid biomarker profile, cerebral perfusion, and cerebral ketone body uptake in older adults at risk for Alzheimer's disease: a pilot study.

Neth BJ, Mintz A, Whitlow C, Jung Y, Solingapuram Sai K, Register TC, Kellar D, Lockhart SN, Hoscheidt S, Maldjian J, Heslegrave AJ, Blennow K, Cunnane SC, Castellano CA, Zetterberg H, Craft S · Neurobiology of aging · 2019-09-26

Clinical trial / intervention

64. Lessons learned from recent clinical trials of ketogenic diet therapies in adults.

McDonald TJW, Cervenka MC · Current opinion in clinical nutrition and metabolic care · 2019-09-11

Randomized clinical trial

65. Modified Mediterranean-ketogenic diet modulates gut microbiome and short-chain fatty acids in association with Alzheimer's disease markers in subjects with mild cognitive impairment.

Nagpal R, Neth BJ, Wang S, Craft S, Yadav H · EBioMedicine · 2019-08-30

Clinical trial / intervention

66. Ketogenic Diet in Alzheimer's Disease.

Rusek M, Pluta R, Ułamek-Kozioł M, Czuczwar SJ · International journal of molecular sciences · 2019-08-09

Clinical trial / intervention

67. Nutritional ketosis for mild cognitive impairment in Parkinson's disease: A controlled pilot trial.

Krikorian R, Shidler MD, Summer SS, Sullivan PG, Duker AP, Isaacson RS, Espay AJ · Clinical parkinsonism & related disorders · 2019-08-06

Clinical trial / intervention

68. An Experimental Ketogenic Diet for Alzheimer Disease Was Nutritionally Dense and Rich in Vegetables and Avocado.

Taylor MK, Swerdlow RH, Burns JM, Sullivan DK · Current developments in nutrition · 2019-02-20

Review

69. The ketogenic diet as a potential treatment and prevention strategy for Alzheimer's disease.

Broom GM, Shaw IC, Rucklidge JJ · Nutrition (Burbank, Los Angeles County, Calif.) · 2018-10-10

Clinical trial / intervention

70. Ketogenic diet rescues cognition in ApoE4+ patient with mild Alzheimer's disease: A case study.

Morrill SJ, Gibas KJ · Diabetes & metabolic syndrome · 2019-01-24

Randomized clinical trial

71. Effects of a medium-chain triglyceride-based ketogenic formula on cognitive function in patients with mild-to-moderate Alzheimer's disease.

Ota M, Matsuo J, Ishida I, Takano H, Yokoi Y, Hori H, Yoshida S, Ashida K, Nakamura K, Takahashi T, Kunugi H · Neuroscience letters · 2018-10-24

Review

72. Role of Ketogenic Diets in Neurodegenerative Diseases (Alzheimer's Disease and Parkinson's Disease).

Włodarek D · Nutrients · 2019-01-15

Randomized clinical trial

73. Preliminary Report on the Feasibility and Efficacy of the Modified Atkins Diet for Treatment of Mild Cognitive Impairment and Early Alzheimer's Disease.

Brandt J, Buchholz A, Henry-Barron B, Vizthum D, Avramopoulos D, Cervenka MC · Journal of Alzheimer's disease : JAD · 2019-03-12

Review

74. Anti-Oxidant and Anti-Inflammatory Activity of Ketogenic Diet: New Perspectives for Neuroprotection in Alzheimer's Disease.

Pinto A, Bonucci A, Maggi E, Corsi M, Businaro R · Antioxidants (Basel, Switzerland) · 2018-04-28

Clinical trial / intervention

75. Ketogenic Medium Chain Triglycerides Increase Brain Energy Metabolism in Alzheimer's Disease.

Croteau E, Castellano CA, Richard MA, Fortier M, Nugent S, Lepage M, Duchesne S, Whittingstall K, Turcotte ÉE, Bocti C, Fülöp T, Cunnane SC · Journal of Alzheimer's disease : JAD · 2018-06-20

Other

76. The Ketogenic Diet: Making a Comeback.

Walczyk T, Wick JY · The Consultant pharmacist : the journal of the American Society of Consultant Pharmacists · 2017-07-14

Preclinical / mechanistic

77. Novel ketone body therapy for managing Alzheimer's disease: An Editorial Highlight for Effects of a dietary ketone ester on hippocampal glycolytic and tricarboxylic acid cycle intermediates and amino acids in a 3xTgAD mouse model of Alzheimer's disease.

Puchowicz MA, Seyfried TN · Journal of neurochemistry · 2017-03-15

Preclinical / mechanistic

78. Effects of a dietary ketone ester on hippocampal glycolytic and tricarboxylic acid cycle intermediates and amino acids in a 3xTgAD mouse model of Alzheimer's disease.

Pawlosky RJ, Kemper MF, Kashiwaya Y, King MT, Mattson MP, Veech RL · Journal of neurochemistry · 2017-03-15

Preclinical / mechanistic

79. White Matter Lipids as a Ketogenic Fuel Supply in Aging Female Brain: Implications for Alzheimer's Disease.

Klosinski LP, Yao J, Yin F, Fonteh AN, Harrington MG, Christensen TA, Trushina E, Brinton RD · EBioMedicine · 2015-11-03

Case report / case series

80. A new way to produce hyperketonemia: use of ketone ester in a case of Alzheimer's disease.

Newport MT, VanItallie TB, Kashiwaya Y, King MT, Veech RL · Alzheimer's & dementia : the journal of the Alzheimer's Association · 2014-10-07

Preclinical / mechanistic

81. Early decline in glucose transport and metabolism precedes shift to ketogenic system in female aging and Alzheimer's mouse brain: implication for bioenergetic intervention.

Ding F, Yao J, Rettberg JR, Chen S, Brinton RD · PloS one · 2013-11-11

Preclinical / mechanistic

82. Ketogenic diet improves motor performance but not cognition in two mouse models of Alzheimer's pathology.

Brownlow ML, Benner L, D'Agostino D, Gordon MN, Morgan D · PloS one · 2013-09-12

Preclinical / mechanistic

83. A ketone ester diet exhibits anxiolytic and cognition-sparing properties, and lessens amyloid and tau pathologies in a mouse model of Alzheimer's disease.

Kashiwaya Y, Bergman C, Lee JH, Wan R, King MT, Mughal MR, Okun E, Clarke K, Mattson MP, Veech RL · Neurobiology of aging · 2012-12-29

Preclinical / mechanistic

84. Triheptanoin supplementation to ketogenic diet curbs cognitive impairment in APP/PS1 mice used as a model of familial Alzheimer's disease.

Aso E, Semakova J, Joda L, Semak V, Halbaut L, Calpena A, Escolano C, Perales JC, Ferrer I · Current Alzheimer research · 2012-04-04

Review

85. [Anticonvulsant and neuroprotective effects of the ketogenic diet].

Choragiewicz T, Zarnowska I, Gasior M, Zarnowski T · Przeglad lekarski · 2010-08-07

Randomized clinical trial

86. Study of the ketogenic agent AC-1202 in mild to moderate Alzheimer's disease: a randomized, double-blind, placebo-controlled, multicenter trial.

Henderson ST, Vogel JL, Barr LJ, Garvin F, Jones JJ, Costantini LC · Nutrition & metabolism · 2009-08-10

Clinical trial / intervention

87. Ketone bodies as a therapeutic for Alzheimer's disease.

Henderson ST · Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2008-07-16

Clinical trial / intervention

88. Neuroprotective and disease-modifying effects of the ketogenic diet.

Gasior M, Rogawski MA, Hartman AL · Behavioural pharmacology · 2006-08-31

Preclinical / mechanistic

89. A ketogenic diet reduces amyloid beta 40 and 42 in a mouse model of Alzheimer's disease.

Van der Auwera I, Wera S, Van Leuven F, Henderson ST · Nutrition & metabolism · 2005-10-17

Clinical trial / intervention

90. Medium-chain triglycerides and ketogenic diet prevent alterations of the gut microbiome in transgenic Alzheimer's disease mice.

M'Bra PEH, Suárez-Uribe I, Avino M, Ng Kwan Lim E, Mayhue M, Balthazar P, Aumont A, Prévost K, Massé E, Fernandes KJL · Communications biology · 2025-12-07

Systematic review / meta-analysis

91. The Effect of Exogenous Ketone Bodies on Cognition in Patients with Mild Cognitive Impairment, Alzheimer's Disease and in Healthy Adults: A Systematic Review and Meta-Analysis.

Bonnechère B, Stephens EB, Boileau AC, Ducker M, Stubbs BJ · medRxiv : the preprint server for health sciences · 2025-09-18

Preclinical / mechanistic

92. The Impact of Ketogenic Diet Consumption on the Sporadic Alzheimer's Model Through MT1/MT2 Regulation.

Cimen YA, Elibol B, Korkmaz ND, Yuzgulec M, Kinsiz B, Kutlu S, Ustunova S · Journal of neuroscience research · 2025-06-19

Systematic review / meta-analysis

93. Efficacy and Safety of Exogenous Ketones in People with Mild Neurocognitive Disorder and Alzheimer's Disease: A Systematic Literature Review.

Krolak-Salmon P, Swerdlow RH, Mastain T, Dive-Pouletty C, Pooley N, Kisomi M · Nutrition reviews · 2025-02-12

Parkinson’s Disease Recent peer-reviewed literature

Source-audited references from the connected PDF archive. Only papers directly relevant to this topic and ketogenic therapy/ketosis are shown.

1. Exploring the role of gut microbiota in potential mechanism of ketogenic diet in alleviating Parkinson’s disease symptoms

Bibliographic record reviewed for inclusion in the curated Scientific Library.

2. Ketogenic diet protects MPTP-induced mouse model of Parkinson’s disease via altering gut microbiota and metabolites

Bibliographic record reviewed for inclusion in the curated Scientific Library.

3. Nutritional Ketosis in Parkinson’s Disease

Bibliographic record reviewed for inclusion in the curated Scientific Library.

4. Ketogenic interventions in mild cognitive impairment, Alzheimer’s disease, and Parkinson’s disease: a systematic review and critical appraisal

Bibliographic record reviewed for inclusion in the curated Scientific Library.

5. Dietary approaches to improve efficacy and management in Parkinson’s disease with ketogenic strategies

Bibliographic record reviewed for inclusion in the curated Scientific Library.

6. The role of diet and dietary patterns in Parkinson’s disease, including ketogenic approaches

Bibliographic record reviewed for inclusion in the curated Scientific Library.

7. Outcomes of dietary interventions in the prevention and progression of Parkinson's disease

Bibliographic record reviewed for inclusion in the curated Scientific Library.

8. The Efficacy of Ketogenic Therapies in the Clinical Management of People with Neurodegenerative Disease

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Recent disease-focused review · 2026

9. Exploring the Role of Gut Microbiota in the Potential Mechanism of Ketogenic Diet in Alleviating Parkinson’s Disease Symptoms

Original publication title: Exploring the Role of Gut Microbiota in the Potential Mechanism of Ketogenic Diet in Alleviating Parkinson’s Disease Symptoms

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Preclinical mechanistic study · 2023

10. Ketogenic Diet Protects an MPTP-Induced Mouse Model of Parkinson’s Disease via Altering Gut Microbiota and Metabolites

Original publication title: Ketogenic Diet Protects an MPTP-Induced Mouse Model of Parkinson’s Disease via Altering Gut Microbiota and Metabolites

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Mechanistic review

11. Ketone Bodies and Brain Metabolism: New Insights and Perspectives for Neurological Diseases

Original publication title: Ketone Bodies and Brain Metabolism: New Insights and Perspectives for Neurological Diseases

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Review

12. Effects of Ketogenic Diet on Neuroinflammation in Neurodegenerative Diseases

Original publication title: Effects of Ketogenic Diet on Neuroinflammation in Neurodegenerative Diseases

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Mechanistic review

13. Neuroprotection by the Ketogenic Diet

Original publication title: Neuroprotection by the Ketogenic Diet

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Review

14. Effects of Ketone Bodies on Brain Metabolism and Function in Neurodegenerative Diseases

Original publication title: Effects of Ketone Bodies on Brain Metabolism and Function in Neurodegenerative Diseases

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Review

15. Ketogenic diet and Parkinson's disease.

Ye Y, Li S, Chen T · Frontiers in molecular neuroscience · 2026-08-05

Preclinical / mechanistic

16. Ketogenic β-hydroxybutyrate-regulated β-hydroxybutyrylation of HSPE1 alleviates neuronal apoptosis in MPTP/MPP+ induced Parkinson's disease models.

Liu Y, Wang M, Shi S, Zhang J, Wang W, Xiang J · Food & function · 2026-08-03

Randomized clinical trial

17. A fat chance at neuroprotection: Ketogenic diet and Parkinson's disease.

Hitawala G, Shulman LM · Clinical nutrition ESPEN · 2026-06-25

Randomized clinical trial

18. A randomized feasibility trial of medium chain triglyceride-supplemented ketogenic diet in people with Parkinson's disease.

Choi AH, Delgado M, Chen KY, Chung ST, Courville A, Turner SA, Yang S, Airaghi K, Dustin I, McGurrin P, Wu T, Hallett M, Ehrlich DJ · BMC neurology · 2024-04-01

Clinical trial / intervention

19. The Anti-Inflammatory Effect of Preventive Intervention with Ketogenic Diet Mediated by the Histone Acetylation of mGluR5 Promotor Region in Rat Parkinson's Disease Model: A Dual-Tracer PET Study.

Zhu Y, Tang X, Cheng Z, Dong Q, Ruan G · Parkinson's disease · 2022-09-05

Systematic review / meta-analysis

20. Ketogenic therapy for Parkinson's disease: A systematic review and synthesis without meta-analysis of animal and human trials.

Grammatikopoulou MG, Tousinas G, Balodimou C, Anastasilakis DA, Gkiouras K, Dardiotis E, Evangeliou AE, Bogdanos DP, Goulis DG · Maturitas · 2022-06-09

Other

21. Effect of ketogenic diet versus regular diet on voice quality of patients with Parkinson's disease.

Koyuncu H, Fidan V, Toktas H, Binay O, Celik H · Acta neurologica Belgica · 2020-09-06

Clinical trial / intervention

22. Increased Beta-Hydroxybutyrate Level Is Not Sufficient for the Neuroprotective Effect of Long-Term Ketogenic Diet in an Animal Model of Early Parkinson's Disease. Exploration of Brain and Liver Energy Metabolism Markers.

Kuter KZ, Olech Ł, Głowacka U, Paleczna M · International journal of molecular sciences · 2021-07-14

Review

23. Correction to: Nutritional Ketosis in Parkinson's Disease - a Review of Remaining Questions and Insights.

Choi A, Hallett M, Ehrlich D · Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2021-07-27

Review

24. Nutritional Ketosis in Parkinson's Disease - a Review of Remaining Questions and Insights.

Choi A, Hallett M, Ehrlich D · Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2021-07-07

Systematic review / meta-analysis

25. Use of ketogenic diets in the treatment of central nervous system diseases: a systematic review.

Christensen MG, Damsgaard J, Fink-Jensen A · Nordic journal of psychiatry · 2020-08-06

Clinical trial / intervention

26. Nutritional ketosis for mild cognitive impairment in Parkinson's disease: A controlled pilot trial.

Krikorian R, Shidler MD, Summer SS, Sullivan PG, Duker AP, Isaacson RS, Espay AJ · Clinical parkinsonism & related disorders · 2019-08-06

Review

27. Role of Ketogenic Diets in Neurodegenerative Diseases (Alzheimer's Disease and Parkinson's Disease).

Włodarek D · Nutrients · 2019-01-15

Other

28. A new validated HPLC method for the determination of levodopa: Application to study the impact of ketogenic diet on the pharmacokinetics of levodopa in Parkinson's participants.

Elbarbry F, Nguyen V, Mirka A, Zwickey H, Rosenbaum R · Biomedical chromatography : BMC · 2018-10-17

Randomized clinical trial

29. Low-fat versus ketogenic diet in Parkinson's disease: A pilot randomized controlled trial.

Phillips MCL, Murtagh DKJ, Gilbertson LJ, Asztely FJS, Lynch CDP · Movement disorders : official journal of the Movement Disorder Society · 2018-08-11

Randomized clinical trial

30. The efficacy of the ketogenic diet on motor functions in Parkinson's disease: A rat model.

Shaafi S, Najmi S, Aliasgharpour H, Mahmoudi J, Sadigh-Etemad S, Farhoudi M, Baniasadi N · Iranian journal of neurology · 2016-06-22

Review

31. [Anticonvulsant and neuroprotective effects of the ketogenic diet].

Choragiewicz T, Zarnowska I, Gasior M, Zarnowski T · Przeglad lekarski · 2010-08-07

Preclinical / mechanistic

32. Ketogenic diet protects dopaminergic neurons against 6-OHDA neurotoxicity via up-regulating glutathione in a rat model of Parkinson's disease.

Cheng B, Yang X, An L, Gao B, Liu X, Liu S · Brain research · 2009-06-25

Clinical trial / intervention

33. Changing chronomics of clock, immune and Parkinson's disease-associated genes in SCN and SN with aging in male Wistar rats: ketogenic diet intervention.

Sharma SA, Jagota A · Biogerontology · 2025-12-08

Clinical trial / intervention

34. The ketogenic diet in Parkinson's disease: a potential therapeutic strategy.

Pokora B, Pokora K, Binienda A, Fichna J · Pharmacological reports : PR · 2025-11-07

Clinical trial / intervention

35. Exploring the Facilitators and Barriers of Adherence to Mediterranean-Ketogenic Dietary Interventions in Parkinson's Disease: A Qualitative Study.

Tosefsky KN, Wang YN, Lam JS, Cohen TR, Appel-Cresswell S · Current developments in nutrition · 2025-10-30

Review

36. Effects of Ketogenic Diet on Quality of Life in Parkinson Disease: An Integrative Review.

Golob MG, Mancin S, Lopane D, Coldani C, Cattani D, Dacomi A, Tomaiuolo G, Petrelli F, Cangelosi G, Cosmai S, Santagostino AM, Mazzoleni B · Nutrients · 2025-10-24

Huntington’s Disease Recent peer-reviewed literature

Source-audited selection from the connected PDF archive. Systematic reviews/meta-analyses and recent human evidence are prioritized when available; sparse areas are explicitly kept sparse.

Direct disease-focused study

1. Time-Restricted Ketogenic Diet in Huntington's Disease

Original publication title: Time-Restricted Ketogenic Diet in Huntington's Disease

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Preclinical disease-focused study

2. Dietary Ketosis Improves Metabolic and Neurological Features in Experimental Huntington’s Disease

Original publication title: Dietary Ketosis Improves Metabolic and Neurological Features in Experimental Huntington’s Disease

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Case report / case series

3. Time-Restricted Ketogenic Diet in Huntington's Disease: A Case Study.

Phillips MCL, McManus EJ, Brinkhuis M, Romero-Ferrando B · Frontiers in behavioral neuroscience · 2022-07-29

Preclinical / mechanistic

4. A ketogenic diet delays weight loss and does not impair working memory or motor function in the R6/2 1J mouse model of Huntington's disease.

Ruskin DN, Ross JL, Kawamura M, Ruiz TL, Geiger JD, Masino SA · Physiology & behavior · 2011-04-09

Neurodegenerative Disorders Recent peer-reviewed literature

Source-audited references from the connected PDF archive. Only papers directly relevant to this topic and ketogenic therapy/ketosis are shown.

1. Exploring the Neurological Impacts of the Ketogenic Diet

Bibliographic record reviewed for inclusion in the curated Scientific Library.

2. Exploring the ketogenic diet's potential in reducing neuroinflammation and modulating immune responses

Bibliographic record reviewed for inclusion in the curated Scientific Library.

3. Molecular Mechanisms of Neuroprotection by Ketone Bodies and Ketogenic Diet in Cerebral Ischemia and Neurodegenerative Diseases

Bibliographic record reviewed for inclusion in the curated Scientific Library.

4. Ketone Bodies and Brain Metabolism: New Insights and Perspectives for Neurological Diseases

Bibliographic record reviewed for inclusion in the curated Scientific Library.

5. The Ketogenic Diet and Neuroinflammation: The Action of Beta-Hydroxybutyrate in a Microglial Cell Line

Bibliographic record reviewed for inclusion in the curated Scientific Library.

6. β-Hydroxybutyrate Regulates Activated Microglia to Alleviate Neurodegenerative Processes in Neurological Diseases: A Scoping Review

Bibliographic record reviewed for inclusion in the curated Scientific Library.

7. The Role of Ketogenic Diet in the Treatment of Neurological Diseases

Bibliographic record reviewed for inclusion in the curated Scientific Library.

8. Ketogenic diets and Ketone supplementation: A strategy for therapeutic intervention

Bibliographic record reviewed for inclusion in the curated Scientific Library.

9. Regulation of gut microbiome by ketogenic diet in neurodegenerative diseases: A molecular crosstalk

Bibliographic record reviewed for inclusion in the curated Scientific Library.

10. Effects of Ketogenic Diet on Neuroinflammation in Neurodegenerative Diseases

Bibliographic record reviewed for inclusion in the curated Scientific Library.

11. The Therapeutic Role of Ketogenic Diet in Neurological Disorders

Bibliographic record reviewed for inclusion in the curated Scientific Library.

12. The Efficacy of Ketogenic Therapies in the Clinical Management of People with Neurodegenerative Disease

Bibliographic record reviewed for inclusion in the curated Scientific Library.

13. Ketotherapeutics for neurodegenerative diseases

Bibliographic record reviewed for inclusion in the curated Scientific Library.

14. Effects of Ketone Bodies on Brain Metabolism and Function in Neurodegenerative Diseases

Bibliographic record reviewed for inclusion in the curated Scientific Library.

15. Neuroprotection by the ketogenic diet

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Review / mechanistic evidence

16. The Implication of Physiological Ketosis on Cognitive Function

Original publication title: The Implication of Physiological Ketosis on Cognitive Function

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Human case series

17. Feasibility and Tolerability of Ketogenic Interventions in Amyotrophic Lateral Sclerosis—A Dose-Finding Case Series

Original publication title: Feasibility and Tolerability of Ketogenic Interventions in Amyotrophic Lateral Sclerosis—A Dose-Finding Case Series

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Interdisciplinary review

18. Investigating the Therapeutic Potential of the Ketogenic Diet in Modulating Neurodegenerative Pathophysiology: An Interdisciplinary Approach

Original publication title: Investigating the Therapeutic Potential of the Ketogenic Diet in Modulating Neurodegenerative Pathophysiology: An Interdisciplinary Approach

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Mechanistic review

19. Brain Ketone Bodies in Health, Evolution and Disease

Original publication title: Brain Ketone Bodies in Health, Evolution and Disease

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Review

20. The Role of the Ketogenic Diet in Modulating Biochemical Pathophysiology in Psychiatric and Neurodegenerative Disorders.

Chang YB, Baleja JD · International journal of molecular sciences · 2026-05-29

Review

21. Ketogenic diet as a therapeutic strategy for neurodegenerative diseases: from mechanisms to translational challenges.

Salgueiro AM, Ferreira-Marques M, Ribeiro RFN, Lopes SM, Pereira D, Costa DG, Santana MM, de Almeida LP, Cavadas C · Translational neurodegeneration · 2026-05-25

Clinical trial / intervention

22. From Refractory Epilepsy to Neurodegeneration: Emerging Mechanistic and Clinical Insights Into the Ketogenic Diet.

Ahire C, Yadav R, Bhamare UU, Kaur G, Palkar MB · FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026-01-25

Review

23. Role of ketogenic diet in neurodegenerative diseases focusing on Alzheimer diseases: The guardian angle.

Al-Kuraishy HM, Jabir MS, Albuhadily AK, Al-Gareeb AI, Jawad SF, Swelum AA, Hadi NR · Ageing research reviews · 2024-02-14

Other

24. Is there evidence of a ketogenic effect of coconut oil? Commentary: Effect of the Mediterranean diet supplemented with nicotinamide riboside and pterostilbene and/or coconut oil on anthropometric variables in amyotrophic lateral sclerosis. A pilot study.

Norgren J, Kåreholt I, Sindi S · Frontiers in nutrition · 2024-01-08

Randomized clinical trial

25. The Relationship of Ketogenic Diet with Neurodegenerative and Psychiatric Diseases: A Scoping Review from Basic Research to Clinical Practice.

Mentzelou M, Dakanalis A, Vasios GK, Gialeli M, Papadopoulou SK, Giaginis C · Nutrients · 2023-05-11

Review

26. ALSUntangled #63: ketogenic diets.

Bedlack R, Barkhaus PE, Barnes B, Beauchamp M, Bertorini T, Bromberg MB, Carter GT, Chaudry V, Cudkowicz M, Jackson C, Levitsky G, Lund I, McDermott C, Novella S, Olby N, Ostrow L, Pattee GL, Heiman-Patterson T, Ratner D, Salmon K, Steves S, Terrelonge M, Wicks P, Wills AM · Amyotrophic lateral sclerosis & frontotemporal degeneration · 2021-10-14

Review

27. Ketogenic Diet: An Effective Treatment Approach for Neurodegenerative Diseases.

Tao Y, Leng SX, Zhang H · Current neuropharmacology · 2022-01-15

Review

28. The Effect of the Ketogenic Diet on the Therapy of Neurodegenerative Diseases and Its Impact on Improving Cognitive Functions.

Grochowska K, Przeliorz A · Dementia and geriatric cognitive disorders extra · 2022-05-30

Observational human study

29. Study protocol on the safety and feasibility of a normocaloric ketogenic diet in people with amyotrophic lateral sclerosis.

De Marchi F, Collo A, Scognamiglio A, Cavaletto M, Bozzi Cionci N, Biroli G, Di Gioia D, Riso S, Mazzini L · Nutrition (Burbank, Los Angeles County, Calif.) · 2021-10-23

Randomized clinical trial

30. The Ketogenic Diet and Alzheimer's Disease.

Hersant H, Grossberg G · The journal of nutrition, health & aging · 2022-06-19

Systematic review / meta-analysis

31. The Efficacy of Ketogenic Therapies in the Clinical Management of People with Neurodegenerative Disease: A Systematic Review.

Dewsbury LS, Lim CK, Steiner GZ · Advances in nutrition (Bethesda, Md.) · 2020-08-24

Clinical trial / intervention

32. Nutritional ketosis as an intervention to relieve astrogliosis: Possible therapeutic applications in the treatment of neurodegenerative and neuroprogressive disorders.

Morris G, Maes M, Berk M, Carvalho AF, Puri BK · European psychiatry : the journal of the Association of European Psychiatrists · 2020-01-31

Review

33. Therapeutic alternative of the ketogenic Mediterranean diet to improve mitochondrial activity in Amyotrophic Lateral Sclerosis (ALS): A Comprehensive Review.

Caplliure-Llopis J, Peralta-Chamba T, Carrera-Juliá S, Cuerda-Ballester M, Drehmer-Rieger E, López-Rodriguez MM, de la Rubia Ortí JE · Food science & nutrition · 2019-12-16

Review

34. Role of Ketogenic Diets in Neurodegenerative Diseases (Alzheimer's Disease and Parkinson's Disease).

Włodarek D · Nutrients · 2019-01-15

Review

35. The Therapeutic Potential of Ketogenic Diet Throughout Life: Focus on Metabolic, Neurodevelopmental and Neurodegenerative Disorders.

Kraeuter AK, Guest PC, Sarnyai Z · Advances in experimental medicine and biology · 2019-09-08

Review

36. Kynurenic Acid and Neuroprotective Activity of the Ketogenic Diet in the Eye.

Zarnowski T, Tulidowicz-Bielak M, Zarnowska I, Mitosek-Szewczyk K, Wnorowski A, Jozwiak K, Gasior M, Turski WA · Current medicinal chemistry · 2016-12-30

Preclinical / mechanistic

37. A ketogenic diet accelerates neurodegeneration in mice with induced mitochondrial DNA toxicity in the forebrain.

Lauritzen KH, Hasan-Olive MM, Regnell CE, Kleppa L, Scheibye-Knudsen M, Gjedde A, Klungland A, Bohr VA, Storm-Mathisen J, Bergersen LH · Neurobiology of aging · 2016-08-18

Review

38. Ketogenic diet in neuromuscular and neurodegenerative diseases.

Paoli A, Bianco A, Damiani E, Bosco G · BioMed research international · 2014-07-03

Randomized clinical trial

39. High-fat and ketogenic diets in amyotrophic lateral sclerosis.

Paganoni S, Wills AM · Journal of child neurology · 2013-05-10

Preclinical / mechanistic

40. Neuroprotective and anti-inflammatory activities of ketogenic diet on MPTP-induced neurotoxicity.

Yang X, Cheng B · Journal of molecular neuroscience : MN · 2010-03-24

Clinical trial / intervention

41. The ketogenic diet: uses in epilepsy and other neurologic illnesses.

Barañano KW, Hartman AL · Current treatment options in neurology · 2008-11-08

Clinical trial / intervention

42. Neuroprotective and disease-modifying effects of the ketogenic diet.

Gasior M, Rogawski MA, Hartman AL · Behavioural pharmacology · 2006-08-31

Other

43. Can ketogenic diet slow progression of ALS?

Siva N · The Lancet. Neurology · 2006-06-03

Clinical trial / intervention

44. A ketogenic diet as a potential novel therapeutic intervention in amyotrophic lateral sclerosis.

Zhao Z, Lange DJ, Voustianiouk A, MacGrogan D, Ho L, Suh J, Humala N, Thiyagarajan M, Wang J, Pasinetti GM · BMC neuroscience · 2006-04-03

Clinical trial / intervention

45. Nutritional Interventions in Amyotrophic Lateral Sclerosis: From Ketogenic Diet and Neuroprotective Nutrients to the Microbiota-Gut-Brain Axis Regulation.

Nabakhteh S, Lotfi A, Afsartaha A, Khodadadi ES, Abdolghaderi S, Mohammadpour M, Shokri Y, Kiani P, Ehtiati S, Khakshournia S, Khatami SH · Molecular neurobiology · 2025-03-17

GLUT1 Deficiency Syndrome Recent peer-reviewed literature

Source-audited selection from the connected PDF archive. Systematic reviews/meta-analyses and recent human evidence are prioritized when available; sparse areas are explicitly kept sparse.

Disease-focused review

1. Glucose Transporter Type 1 Deficiency Syndrome

Original publication title: Glucose Transporter Type 1 Deficiency Syndrome

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Observational human study

2. Glucose Transporter Type 1 Deficiency Syndrome: Clinical Variability and Challenges in Ketogenic Diet Management in a Paediatric Case Series.

Viegas M, Baptista N, Martins F, Almeida J, Pereira C, Rodrigues F, Salgado J, Ribeiro J, Ferreira S, Diogo R · Journal of clinical medicine · 2026-08-19

Other

3. [Ketogenic diet reintroduction in an adult patient with glucose transporter type 1 deficiency syndrome].

Kusakabe S, Osakada Y, Morihara R, Dohi Y, Shimono K, Ishiura H · Rinsho shinkeigaku = Clinical neurology · 2026-08-07

Other

4. "Not always the magic bullet"-Insufficient seizure control by ketogenic dietary therapies in Glut1 Deficiency Syndrome.

Klepper J, Runkel E, Kiesel L · Epilepsia open · 2026-03-14

Other

5. Knowledge and attitudes toward ketogenic dietary therapy in adults with epilepsy.

Lutz MT, Alex M, Brandhoff F, Mayer T · Epilepsy & behavior : E&B · 2026-02-17

Observational human study

6. Glucose transporter type 1 deficiency syndrome: Phenotypes, molecular findings, and ketogenic therapy implementation in Argentina.

Armeno ML, Massaro M, Boccoli J, Caballero E, Chacon S, Diz M, Espeche A, Fasulo L, Galarza N, Gonzalez L, Kobayashi V, Loos M, Semprino M, Veneruzzo G, Verini A, Caraballo R · Epileptic disorders : international epilepsy journal with videotape · 2026-02-02

Observational human study

7. Managing GLUT 1 Deficiency with the Ketogenic Diet: A Retrospective Look at Seizures, Medications, and Side Effects in a Pediatric Cohort.

Morris S, Blackford R, Lowman W, Fisher B · Journal of child neurology · 2026-01-09

Observational human study

8. Weaning from ketogenic diet therapy in children with epilepsy: Insights from a retrospective study.

Donnard N, Dozières-Puyravel B, Geraldes K, Perrot C, Quéméner V, Goujon E, Truchy P, Nasser H, Mauvais FX, Danse M, Auvin S · Epilepsia · 2025-12-24

Observational human study

9. Benefits and adverse effects of ketogenic diet treatment in pediatric patients with inborn errors of metabolism.

Wesół-Kucharska D, Kaczor MA, Emczyńska-Seliga EEV · Advances in clinical and experimental medicine : official organ Wroclaw Medical University · 2025-11-22

Review

10. Exploring ketogenic diet resistance in glucose transporter type 1 deficiency syndrome: A comprehensive review and critical appraisal.

Falsaperla R, Sortino V, Kluger GJ, Herberhold T, Rüegger A, Striano P, Ruggieri M, Klepper J, Ramantani G · Epilepsia open · 2024-12-06

Systematic review / meta-analysis

11. Utilization of EEG microstates as a prospective biomarker for assessing the impact of ketogenic diet in GLUT1-DS.

Chen J, Jin L, Lin N · Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2024-04-08

Case report / case series

12. GLUT-1DS resistant to ketogenic diet: from clinical feature to in silico analysis. An exemplificative case report with a literature review.

Falsaperla R, Sortino V, Vitaliti G, Privitera GF, Ruggieri M, Fusto G, Pappalardo XG · Neurogenetics · 2024-01-08

Observational human study

13. Novel insight into GLUT1 deficiency syndrome: screening for emotional and behavioral problems in youths following ketogenic diet.

Varesio C, Zanaboni MP, Pasca L, Provenzi L, Ferraris C, Tagliabue A, Pezzotti E, Carpani A, Veggiotti P, DE Giorgis V · Minerva pediatrics · 2021-04-02

Review

14. Is ketogenic diet a 'precision medicine'? Recent developments and future challenges.

Falsaperla R, Sortino V, Striano P, Kluger G, Ramantani G, Ruggieri M, Network for Therapy in Rare Epilepsies (NETRE) · European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society · 2023-11-15

Clinical trial / intervention

15. Nutritional Intervention Through Ketogenic Diet in GLUT1 Deficiency Syndrome.

Kim YS, Kim W, Na JH, Lee YM · Clinical nutrition research · 2023-07-26

Clinical trial / intervention

16. Case report: KETOLAND the psychoeducation program for ketogenic diet.

Zanaboni MP, Pasca L, Geraci MA, Varesio C, Guglielmetti M, Tagliabue A, Grumi S, De Giorgis V · Frontiers in psychiatry · 2023-06-08

Other

17. Combination of triheptanoin with the ketogenic diet in Glucose transporter type 1 deficiency (G1D).

Avila A, Málaga I, Sirsi D, Kayani S, Primeaux S, Kathote GA, Jakkamsetti V, Kallem RR, Putnam WC, Park JY, Shinnar S, Pascual JM · Scientific reports · 2023-06-02

Observational human study

18. Role of EEG as a monitoring tool in patients with glucose transporter type I deficiency syndrome (GLUT1-DS) on ketogenic diet.

Toro-Perez J, Healy S, Sell E, Bulusu S, Whiting S · Epileptic disorders : international epilepsy journal with videotape · 2023-05-06

Clinical trial / intervention

19. Long-term follow-up of nutritional status in children with GLUT1 Deficiency Syndrome treated with classic ketogenic diet: a 5-year prospective study.

De Amicis R, Leone A, Pellizzari M, Foppiani A, Battezzati A, Lessa C, Tagliabue A, Ferraris C, De Giorgis V, Olivotto S, Previtali R, Veggiotti P, Bertoli S · Frontiers in nutrition · 2023-05-24

Case report / case series

20. Timing of Ketogenic Dietary Therapy (KDT) Introduction and Its Impact on Cognitive Profiles in Children with Glut1-DS-A Preliminary Study.

Barthold M, Jurkutat A, Goetz R, Schubring L, Spiegler J, Fries AS, Kiesel L, Klepper J · Children (Basel, Switzerland) · 2023-04-03

Case report / case series

21. Classic ketogenic diet in parenteral nutrition in a GLUT1DS patient: Doing more with less in an acute surgical setting.

De Giorgis V, Ferraris C, Brena ML, Farris G, Gentilino V, Guglielmetti M, Marazzi C, Pasca L, Trentani C, Tagliabue A, Varesio C · Frontiers in nutrition · 2023-02-15

Other

22. Withdrawn: Parenteral Nutrition in a GLUT1DS Patient Following Classic Ketogenic Diet: Ideal versus Real-World Management in an Acute Surgical Setting.

Varesio C, Ferraris C, Gentilino V, Brena ML, Farris G, Guglielmetti M, Marazzi C, Pasca L · JPEN. Journal of parenteral and enteral nutrition · 2022-05-20

Case report / case series

23. Ketogenic Diet in Glut 1 Deficiency Through the Life Cycle: Pregnancy to Neonate to Preschooler.

Kramer J, Smith L · Child neurology open · 2021-09-13

Other

24. Classic Ketogenic Diet and Modified Atkins Diet in SLC2A1 Positive and Negative Patients with Suspected GLUT1 Deficiency Syndrome: A Single Center Analysis of 18 Cases.

Ruiz Herrero J, Cañedo Villarroya E, González Gutiérrez-Solana L, García Alcolea B, Gómez Fernández B, Puerta Macfarland LA, Pedrón-Giner C · Nutrients · 2021-03-04

Observational human study

25. [Clinical characteristics and ketogenic diet therapy of glucose transporter type 1 deficiency syndrome in children: a multicenter clinical study].

Yu LF, Zhang YQ, Duan J, Ni Y, Gong XY, Lu ZY, Liao JX, Lu XP, Shi ZN, Lei MF, Zhong JM, Zha J, Zhou SZ · Zhonghua er ke za zhi = Chinese journal of pediatrics · 2020-10-29

Review

26. Hemiplegic Migraine in Glut1 Deficiency Syndrome and Paroxysmal Dyskinesia at Ketogenic Diet Induction: Case Report and Literature Review.

Gburek-Augustat J, Heinze A, Abou Jamra R, Merkenschlager A · Movement disorders clinical practice · 2020-10-06

Observational human study

27. Use of Remote Monitoring by E-mail for Long-Term Management of the Classic Ketogenic Diet.

Ferraris C, Guglielmetti M, Tamagni E, Trentani C, De Giorgis V, Pasca L, Varesio C, Ferraro OE, Tagliabue A · Nutrients · 2020-06-19

Other

28. Transition from ketogenic diet to triheptanoin in patients with GLUT1 deficiency syndrome.

Hainque E, Meneret A, Gras D, Atencio M, Luton MP, Barbier M, De Saint Martin A, Billette de Villemeur T, Ottolenghi C, Roze E, Mochel F · Journal of neurology, neurosurgery, and psychiatry · 2019-11-06

Review

29. Glucose transporter type 1 deficiency syndrome and the ketogenic diet.

Schwantje M, Verhagen LM, van Hasselt PM, Fuchs SA · Journal of inherited metabolic disease · 2019-11-13

Observational human study

30. Long-Term Effects of a Classic Ketogenic Diet on Ghrelin and Leptin Concentration: A 12-Month Prospective Study in a Cohort of Italian Children and Adults with GLUT1-Deficiency Syndrome and Drug Resistant Epilepsy.

De Amicis R, Leone A, Lessa C, Foppiani A, Ravella S, Ravasenghi S, Trentani C, Ferraris C, Veggiotti P, De Giorgis V, Tagliabue A, Battezzati A, Bertoli S · Nutrients · 2019-07-25

Other

31. Quality of Life in Chronic Ketogenic Diet Treatment: The GLUT1DS Population Perspective.

Varesio C, Pasca L, Parravicini S, Zanaboni MP, Ballante E, Masnada S, Ferraris C, Bertoli S, Tagliabue A, Veggiotti P, De Giorgis V · Nutrients · 2019-07-19

Observational human study

32. Ketogenic Diet in Patients with GLUT1 Deficiency Syndrome.

Sandu C, Burloiu CM, Barca DG, Magureanu SA, Craiu DC · Maedica · 2019-09-17

Observational human study

33. Failure of ketogenic diet therapy in GLUT1 deficiency syndrome.

Bekker YAC, Lambrechts DA, Verhoeven JS, van Boxtel J, Troost C, Kamsteeg EJ, Willemsen MA, Braakman HMH · European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society · 2019-02-27

Preclinical / mechanistic

34. Nutritional ketosis delays the onset of isoflurane induced anesthesia.

Ari C, Kovács Z, Murdun C, Koutnik AP, Goldhagen CR, Rogers C, Diamond D, D'Agostino DP · BMC anesthesiology · 2018-07-18

Other

35. Questionnaire survey on the current status of ketogenic diet therapy in patients with glucose transporter 1 deficiency syndrome (GLUT1DS) in Japan.

Oguni H, Ito Y, Otani Y, Nagata S · European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society · 2017-12-26

Observational human study

36. Prevalence of Genetic Disorders and GLUT1 Deficiency in a Ketogenic Diet Clinic.

Hewson S, Brunga L, Ojeda MF, Imhof E, Patel J, Zak M, Donner EJ, Kobayashi J, Salomons GS, Mercimek-Andrews S · The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques · 2017-11-16

Other

37. Ketone Bodies as a Possible Adjuvant to Ketogenic Diet in PDHc Deficiency but Not in GLUT1 Deficiency.

Habarou F, Bahi-Buisson N, Lebigot E, Pontoizeau C, Abi-Warde MT, Brassier A, Le Quan Sang KH, Broissand C, Vuillaumier-Barrot S, Roubertie A, Boutron A, Ottolenghi C, de Lonlay P · JIMD reports · 2017-05-17

Other

38. Biochemical phenotyping unravels novel metabolic abnormalities and potential biomarkers associated with treatment of GLUT1 deficiency with ketogenic diet.

Cappuccio G, Pinelli M, Alagia M, Donti T, Day-Salvatore DL, Veggiotti P, De Giorgis V, Lunghi S, Vari MS, Striano P, Brunetti-Pierri N, Kennedy AD, Elsea SH · PloS one · 2017-09-29

Preclinical / mechanistic

39. Short-term impact of a classical ketogenic diet on gut microbiota in GLUT1 Deficiency Syndrome: A 3-month prospective observational study.

Tagliabue A, Ferraris C, Uggeri F, Trentani C, Bertoli S, de Giorgis V, Veggiotti P, Elli M · Clinical nutrition ESPEN · 2016-12-18

Other

40. Alternative ketogenic diets in glucose transporter type 1 deficiency syndrome.

De Laet C · Developmental medicine and child neurology · 2016-07-22

Observational human study

41. Use of modified Atkins diet in glucose transporter type 1 deficiency syndrome.

Amalou S, Gras D, Ilea A, Greneche MO, Francois L, Bellavoine V, Delanoe C, Auvin S · Developmental medicine and child neurology · 2016-06-08

Other

42. Outcome of ketogenic diets in GLUT1 deficiency syndrome in Japan: A nationwide survey.

Fujii T, Ito Y, Takahashi S, Shimono K, Natsume J, Yanagihara K, Oguni H · Brain & development · 2016-02-26

Case report / case series

43. Severe Hypertriglyceridemia in Glut1D on Ketogenic Diet.

Klepper J, Leiendecker B, Heussinger N, Lausch E, Bosch F · Neuropediatrics · 2016-02-22

Other

44. GLUT1 deficiency syndrome and ketogenic diet therapies: missing rare but treatable diseases?

Klepper J · Developmental medicine and child neurology · 2015-05-22

Other

45. Do Glut1 (glucose transporter type 1) defects exist in epilepsy patients responding to a ketogenic diet?

Becker F, Schubert J, Weckhuysen S, Suls A, Grüninger S, Korn-Merker E, Hofmann-Peters A, Sperner J, Cross H, Hallmann K, Elger CE, Kunz WS, Madeleyen R, Lerche H, Weber YG · Epilepsy research · 2015-05-01

Review

46. Ketogenic diets in patients with inherited metabolic disorders.

Scholl-Bürgi S, Höller A, Pichler K, Michel M, Haberlandt E, Karall D · Journal of inherited metabolic disease · 2015-06-25

Other

47. Short-term effects of ketogenic diet on anthropometric parameters, body fat distribution, and inflammatory cytokine production in GLUT1 deficiency syndrome.

Bertoli S, Neri IG, Trentani C, Ferraris C, De Amicis R, Battezzati A, Veggiotti P, De Giorgis V, Tagliabue A · Nutrition (Burbank, Los Angeles County, Calif.) · 2015-03-31

Other

48. Does ketogenic diet improve cognitive function in patients with GLUT1-DS? A 6- to 17-month follow-up study.

Ramm-Pettersen A, Stabell KE, Nakken KO, Selmer KK · Epilepsy & behavior : E&B · 2014-09-18

Case report / case series

49. Symptomatic west syndrome secondary to glucose transporter-1(GLUT1) deficiency with complete response to 4:1 ketogenic diet.

Vykuntaraju KN, Bhat S, Sanjay KS, Govindaraju M · Indian journal of pediatrics · 2013-04-19

Case report / case series

50. Alternating hemiplegia of childhood with a de novo mutation in ATP1A3 and changes in SLC2A1 responsive to a ketogenic diet.

Ulate-Campos A, Fons C, Artuch R, Castejón E, Martorell L, Ozelius L, Pascual J, Campistol J · Pediatric neurology · 2013-12-04

Case report / case series

51. Glucose transporter type 1 deficiency syndrome effectively treated with modified Atkins diet.

Haberlandt E, Karall D, Jud V, Baumgartner SS, Zotter S, Rostasy K, Baumann M, Scholl-Buergi S · Neuropediatrics · 2013-07-25

Other

52. Occurrence of GLUT1 deficiency syndrome in patients treated with ketogenic diet.

Ramm-Pettersen A, Nakken KO, Haavardsholm KC, Selmer KK · Epilepsy & behavior : E&B · 2014-02-06

Preclinical / mechanistic

53. Ketogenic diet improves forelimb motor function after spinal cord injury in rodents.

Streijger F, Plunet WT, Lee JH, Liu J, Lam CK, Park S, Hilton BJ, Fransen BL, Matheson KA, Assinck P, Kwon BK, Tetzlaff W · PloS one · 2013-11-04

Observational human study

54. Movement disorders in GLUT1 deficiency syndrome respond to the modified Atkins diet.

Leen WG, Mewasingh L, Verbeek MM, Kamsteeg EJ, van de Warrenburg BP, Willemsen MA · Movement disorders : official journal of the Movement Disorder Society · 2013-06-25

Other

55. Glut1 deficiency syndrome and novel ketogenic diets.

Klepper J, Leiendecker B · Journal of child neurology · 2013-05-10

Case report / case series

56. Oxidative stress markers and phosphorus magnetic resonance spectroscopy in a patient with GLUT1 deficiency treated with modified Atkins diet.

Kitamura Y, Okumura A, Hayashi M, Mori H, Takahashi S, Yanagihara K, Miyata R, Tanuma N, Mimaki T, Abe S, Shimizu T · Brain & development · 2011-08-30

Clinical trial / intervention

57. A modified Atkins diet is promising as a treatment for glucose transporter type 1 deficiency syndrome.

Ito Y, Oguni H, Ito S, Oguni M, Osawa M · Developmental medicine and child neurology · 2011-04-18

Other

58. Glucose transporter type 1 deficiency: ketogenic diet in three patients with atypical phenotype.

Veggiotti P, Teutonico F, Alfei E, Nardocci N, Zorzi G, Tagliabue A, De Giorgis V, Balottin U · Brain & development · 2009-06-09

Case report / case series

59. Intractable seizures, developmental delay, and the ketogenic diet.

Harris ML, Patel H, Garg BP · Seminars in pediatric neurology · 2008-12-17

Case report / case series

60. Modified Atkins diet therapy for a case with glucose transporter type 1 deficiency syndrome.

Ito S, Oguni H, Ito Y, Ishigaki K, Ohinata J, Osawa M · Brain & development · 2007-09-14

Case report / case series

61. GLUT1 deficiency with delayed myelination responding to ketogenic diet.

Klepper J, Engelbrecht V, Scheffer H, van der Knaap MS, Fiedler A · Pediatric neurology · 2006-10-23

Case report / case series

62. [Glucose transponer type 1 deficiency síndrome (GLUT-1 SD) treated with ketogenic diet. Report of one case].

Cornejo VE, Cabello JF, Colombo MC, Raimann EB · Revista medica de Chile · 2007-07-09

Case report / case series

63. Atypical GLUT1 deficiency with prominent movement disorder responsive to ketogenic diet.

Friedman JR, Thiele EA, Wang D, Levine KB, Cloherty EK, Pfeifer HH, De Vivo DC, Carruthers A, Natowicz MR · Movement disorders : official journal of the Movement Disorder Society · 2005-09-09

Clinical trial / intervention

64. Seizure control and acceptance of the ketogenic diet in GLUT1 deficiency syndrome: a 2- to 5-year follow-up of 15 children enrolled prospectively.

Klepper J, Scheffer H, Leiendecker B, Gertsen E, Binder S, Leferink M, Hertzberg C, Näke A, Voit T, Willemsen MA · Neuropediatrics · 2005-10-12

Observational human study

65. [The ketogenic diet in German-speaking countries: update 2003].

Klepper J, Leiendecker B, Riemann E, Baumeister FA · Klinische Padiatrie · 2004-09-30

Other

66. Effects of the ketogenic diet in the glucose transporter 1 deficiency syndrome.

Klepper J, Diefenbach S, Kohlschütter A, Voit T · Prostaglandins, leukotrienes, and essential fatty acids · 2003-06-06

Other

67. Introduction of a ketogenic diet in young infants.

Klepper J, Leiendecker B, Bredahl R, Athanassopoulos S, Heinen F, Gertsen E, Flörcken A, Metz A, Voit T · Journal of inherited metabolic disease · 2003-01-31

Review

68. Toward a working definition of ketogenic diet resistance in GLUT1 deficiency syndrome.

Falsaperla R, Sortino V, Kluger GJ, Herberhold T, Rüegger A, Striano P, Ruggieri M, Klepper J, Ramantani G · Epileptic disorders : international epilepsy journal with videotape · 2025-09-30

Guideline / consensus

69. Ketogenic diet therapy for epilepsy during pregnancy and lactation: An international survey exploring clinician perspectives.

Faltersack K, McDonald TJW, De Giorgis V, Barron B, Cervenka MC, Devlin A, Healy LA, Kverneland M, van der Louw E, Lu M, Zanaboni MP, Armeno M, Felton EA · Epilepsia open · 2025-05-29

Preclinical / mechanistic

70. In Preclinical Epilepsy, GLUT1 and GFAP Dysregulation in Cells Surrounding the Third Ventricle, Including Tanycytes, Is Differentially Restored with Ketogenic Diet Treatment.

Rafiei P, Mian HS, Iyer SH, Draves SB, Matthews SA, Rendon DE, Neesen EJ, Dunlay M, Revis M, Glisan AL, Simeone TA, Simeone KA · Nutrients · 2025-05-28

Pyruvate Dehydrogenase Deficiency Recent peer-reviewed literature

Only directly relevant publications are displayed. Automated search results are not used as bibliography.

Curated references (2)

Ketogenic diet therapy in pyruvate dehydrogenase deficiency: Global clinical practice from literature and survey data

Systematic review + international survey · 2026

Ketogenic diet in pyruvate dehydrogenase complex deficiency: short- and long-term outcomes

J Inherit Metab Dis · 2017 · Cohort + systematic review

Systematic review / meta-analysis

3. Ketogenic diet therapy in pyruvate dehydrogenase deficiency: Global clinical practice from literature and survey data.

Madsen S, Allender B, Blackford R, Bollard T, Comerford A, Johnson ML, Sinha R, Vanatta L, Whiteley VJ, Schoeler NE, Ketogenic Dietitians Research Network · Molecular genetics and metabolism · 2026-06-18

Clinical trial / intervention

4. Prenatal molecular diagnosis of pyruvate dehydrogenase complex deficiency enables rapid initiation of ketogenic diet.

Bowen AB, Rapalino O, Jaimes C, Ratai EM, Zhong Y, Thiele EA, Kritzer A, Ganetzky RD, Gold NB, Walker MA · American journal of medical genetics. Part A · 2024-07-26

Guideline / consensus

5. Classic ketogenic diet-induced ketoacidosis in the treatment of pyruvate dehydrogenase deficiency: a case report and literature review.

Li R, Ma M, Chen W, Qiu Z · BMC pediatrics · 2024-09-28

Case report / case series

6. Ketogenic diet in action: Metabolic profiling of pyruvate dehydrogenase deficiency.

Ogawa E, Hishiki T, Hayakawa N, Suzuki H, Kosaki K, Suematsu M, Takenouchi T · Molecular genetics and metabolism reports · 2023-03-20

Case report / case series

7. Intravenous ketogenic diet therapy for neonatal-onset pyruvate dehydrogenase complex deficiency.

Inui T, Wada Y, Shibuya M, Arai-Ichinoi N, Okubo Y, Endo W, Uchida T, Togashi N, Naito E, Haginoya K · Brain & development · 2021-12-01

Guideline / consensus

8. The Effects of a Ketogenic Diet on Patients with Dihydrolipoamide Dehydrogenase Deficiency.

Staretz-Chacham O, Pode-Shakked B, Kristal E, Abraham SY, Porper K, Wormser O, Shelef I, Anikster Y · Nutrients · 2021-10-07

Case report / case series

9. Efficacy of ketogenic diet for pyruvate dehydrogenase complex deficiency.

Chida R, Shimura M, Nishimata S, Kashiwagi Y, Kawashima H · Pediatrics international : official journal of the Japan Pediatric Society · 2018-11-08

Other

10. Ketone Bodies as a Possible Adjuvant to Ketogenic Diet in PDHc Deficiency but Not in GLUT1 Deficiency.

Habarou F, Bahi-Buisson N, Lebigot E, Pontoizeau C, Abi-Warde MT, Brassier A, Le Quan Sang KH, Broissand C, Vuillaumier-Barrot S, Roubertie A, Boutron A, Ottolenghi C, de Lonlay P · JIMD reports · 2017-05-17

Preclinical / mechanistic

11. Beneficial effect of feeding a ketogenic diet to mothers on brain development in their progeny with a murine model of pyruvate dehydrogenase complex deficiency.

Pliss L, Jatania U, Patel MS · Molecular genetics and metabolism reports · 2016-04-22

Review

12. Ketogenic diets in patients with inherited metabolic disorders.

Scholl-Bürgi S, Höller A, Pichler K, Michel M, Haberlandt E, Karall D · Journal of inherited metabolic disease · 2015-06-25

Case report / case series

13. Case report of pyruvate dehydrogenase deficiency with unusual increase of fats during ketogenic diet treatment.

Di Pisa V, Cecconi I, Gentile V, Di Pietro E, Marchiani V, Verrotti A, Franzoni E · Journal of child neurology · 2012-02-28

Case report / case series

14. Follow-up of a child with pyruvate dehydrogenase deficiency on a less restrictive ketogenic diet.

El-Gharbawy AH, Boney A, Young SP, Kishnani PS · Molecular genetics and metabolism · 2010-11-09

Case report / case series

15. Reconciling diabetes management and the ketogenic diet in a child with pyruvate dehydrogenase deficiency.

Henwood MJ, Thornton PS, Preis CM, Chee C, Grimberg A · Journal of child neurology · 2006-08-12

Preclinical / mechanistic

16. A zebrafish model for pyruvate dehydrogenase deficiency: rescue of neurological dysfunction and embryonic lethality using a ketogenic diet.

Taylor MR, Hurley JB, Van Epps HA, Brockerhoff SE · Proceedings of the National Academy of Sciences of the United States of America · 2004-03-15

Observational human study

17. Caveats when considering ketogenic diets for the treatment of pyruvate dehydrogenase complex deficiency.

Weber TA, Antognetti MR, Stacpoole PW · The Journal of pediatrics · 2001-03-10

Clinical trial / intervention

18. Outcome of pyruvate dehydrogenase deficiency treated with ketogenic diets. Studies in patients with identical mutations.

Wexler ID, Hemalatha SG, McConnell J, Buist NR, Dahl HH, Berry SA, Cederbaum SD, Patel MS, Kerr DS · Neurology · 1997-12-31

Case report / case series

19. Leigh syndrome associated with a deficiency of the pyruvate dehydrogenase complex: results of treatment with a ketogenic diet.

Wijburg FA, Barth PG, Bindoff LA, Birch-Machin MA, van der Blij JF, Ruitenbeek W, Turnbull DM, Schutgens RB · Neuropediatrics · 1992-06-01

Review

20. Ketogenic diet in neonates: effects, pitfalls, and a paradigm from a preterm newborn affected by pyruvate dehydrogenase deficiency.

Katsoudas S, Umana LA, Clarke R, Thomas J, Machie M, Angelis D · Journal of perinatology : official journal of the California Perinatal Association · 2025-09-17

Brain Injury & Neurotrauma Recent peer-reviewed literature

Source-audited selection from the connected PDF archive. Systematic reviews/meta-analyses and recent human evidence are prioritized when available; sparse areas are explicitly kept sparse.

Human clinical study

1. Diet-Induced Ketosis in Adult Patients with Subacute Acquired Brain Injury

Original publication title: Diet-Induced Ketosis in Adult Patients with Subacute Acquired Brain Injury

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Preclinical mechanistic study

2. Modulation of the Autophagy-Lysosomal Pathway and Endoplasmic Reticulum Stress by Ketone Bodies in Experimental Models of Stroke

Original publication title: Modulation of the Autophagy-Lysosomal Pathway and Endoplasmic Reticulum Stress by Ketone Bodies in Experimental Models of Stroke

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Clinical trial / intervention

3. Administration of ketogenic intervention as a potential treatment during post-traumatic brain injury recovery: a scoping review.

Quddus DY, Aydin S, Waheed AA, Zeeshan Q, Hamilton DK, Agarwal N, Maroon JC · Frontiers in nutrition · 2026-05-29

Observational human study

4. Efficacy of Treating Post-Traumatic Epilepsy in Children With Ketogenic Diet.

Choi HW, Bhalla S, Holt P, Johnson M · Journal of child neurology · 2026-04-25

Clinical trial / intervention

5. Modulatory role of the ketogenic diet in glial scar formation after traumatic brain injury: A Fourier transform infrared, Raman, and X-ray fluorescence microscopy study.

Kawon K, Setkowicz Z, Czyzycki M, Rauk Z, Wilk A, Slawek A, Cieslak J, Aquilanti G, Carlomagno I, Drozdz A, Chwiej J · Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy · 2026-03-31

Review

6. Modulation of beta-hydroxybutyrate in traumatic brain injury.

Arora N, Shastri DH, Patel UP, Bhatia K · Current opinion in clinical nutrition and metabolic care · 2024-01-03

Preclinical / mechanistic

7. Ketogenic diet and β-Hydroxybutyrate alleviate ischemic brain injury in mice via an IRAKM-dependent pathway.

Lin C, Wang S, Xie J, Zhu J, Xu J, Liu K, Chen J, Yu M, Zhong H, Huang K, Pan S · European journal of pharmacology · 2023-07-20

Preclinical / mechanistic

8. Ketogenic Diet Modulates Neuroinflammation via Metabolites from Lactobacillus reuteri After Repetitive Mild Traumatic Brain Injury in Adolescent Mice.

Dilimulati D, Zhang F, Shao S, Lv T, Lu Q, Cao M, Jin Y, Jia F, Zhang X · Cellular and molecular neurobiology · 2022-04-30

Preclinical / mechanistic

9. Ketogenic diet attenuates post-cardiac arrest brain injury by upregulation of pentose phosphate pathway-mediated antioxidant defense in a mouse model of cardiac arrest.

Peng F, Zhang YH, Zhang L, Yang M, Chen C, Yu H, Li T · Nutrition (Burbank, Los Angeles County, Calif.) · 2022-08-12

Clinical trial / intervention

10. Western and ketogenic diets in neurological disorders: can you tell the difference?

Habashy KJ, Ahmad F, Ibeh S, Mantash S, Kobeissy F, Issa H, Habis R, Tfaily A, Nabha S, Harati H, Reslan MA, Yehya Y, Barsa C, Shaito A, Zibara K, El-Yazbi AF, Kobeissy FH · Nutrition reviews · 2022-02-17

Clinical trial / intervention

11. Ketogenic diet protects myelin and axons in diffuse axonal injury.

Mu J, Wang T, Li M, Guan T, Guo Y, Zhang X, Zhang G, Kong J · Nutritional neuroscience · 2021-01-23

Randomized clinical trial

12. Phase I single center trial of ketogenic diet for adults with traumatic brain injury.

Arora N, Litofsky NS, Golzy M, Aneja R, Staudenmyer D, Qualls K, Patil S · Clinical nutrition ESPEN · 2021-11-16

Preclinical / mechanistic

13. Ketogenic Diet as a potential treatment for traumatic brain injury in mice.

Har-Even M, Rubovitch V, Ratliff WA, Richmond-Hacham B, Citron BA, Pick CG · Scientific reports · 2021-12-07

Preclinical / mechanistic

14. Ketogenic diet reduces early mortality following traumatic brain injury in Drosophila via the PPARγ ortholog Eip75B.

Blommer J, Fischer MC, Olszewski AR, Katzenberger RJ, Ganetzky B, Wassarman DA · PloS one · 2021-10-26

Review

15. Ketogenic regimens for acute neurotraumatic events.

Yarar-Fisher C, Li J, Womack ED, Alharbi A, Seira O, Kolehmainen KL, Plunet WT, Alaeiilkhchi N, Tetzlaff W · Current opinion in biotechnology · 2021-01-11

Preclinical / mechanistic

16. A new ketogenic formulation improves functional outcome and reduces tissue loss following traumatic brain injury in adult mice.

Thau-Zuchman O, Svendsen L, Dyall SC, Paredes-Esquivel U, Rhodes M, Priestley JV, Feichtinger RG, Kofler B, Lotstra S, Verkuyl JM, Hageman RJ, Broersen LM, van Wijk N, Silva JP, Tremoleda JL, Michael-Titus AT · Theranostics · 2021-01-01

Other

17. The Ketogenic Diet in the Treatment of Post-concussion Syndrome-A Feasibility Study.

Rippee MA, Chen J, Taylor MK · Frontiers in nutrition · 2020-09-10

Clinical trial / intervention

18. Application of ketogenic diets for pediatric neurocritical care.

Lin KL, Lin JJ, Wang HS · Biomedical journal · 2020-07-05

Review

19. Role of the ketogenic diet in acute neurological diseases.

Arora N, Mehta TR · Clinical neurology and neurosurgery · 2020-02-15

Randomized clinical trial

20. The behavioural and pathophysiological effects of the ketogenic diet on mild traumatic brain injury in adolescent rats.

Salberg S, Weerwardhena H, Collins R, Reimer RA, Mychasiuk R · Behavioural brain research · 2019-09-10

Clinical trial / intervention

21. Dietary Supplementation With the Ketogenic Diet Metabolite Beta-Hydroxybutyrate Ameliorates Post-TBI Aggression in Young-Adult Male Drosophila.

Lee DC, Vali K, Baldwin SR, Divino JN, Feliciano JL, Fequiere JR, Fernandez MA, Frageau JC, Longo FK, Madhoun SS, Mingione V P, O'Toole TR, Ruiz MG, Tanner GR · Frontiers in neuroscience · 2019-10-30

Review

22. Ketone Bodies in Neurological Diseases: Focus on Neuroprotection and Underlying Mechanisms.

Yang H, Shan W, Zhu F, Wu J, Wang Q · Frontiers in neurology · 2019-06-12

Preclinical / mechanistic

23. Proton Magnetic Resonance Spectroscopy (H1-MRS) Study of the Ketogenic Diet on Repetitive Mild Traumatic Brain Injury in Adolescent Rats and Its Effect on Neurodegeneration.

Zhang F, Wu H, Jin Y, Zhang X · World neurosurgery · 2018-09-17

Review

24. Exogenous Ketone Bodies as Promising Neuroprotective Agents for Developmental Brain Injury.

Wood TR, Stubbs BJ, Juul SE · Developmental neuroscience · 2019-05-14

Review

25. The ketogenic diet as a treatment for traumatic brain injury: a scoping review.

McDougall A, Bayley M, Munce SE · Brain injury · 2018-01-23

Preclinical / mechanistic

26. Long-Term Effects of Ketogenic Diet on Subsequent Seizure-Induced Brain Injury During Early Adulthood: Relationship of Seizure Thresholds to Zinc Transporter-Related Gene Expressions.

Tian T, Li LL, Zhang SQ, Ni H · Biological trace element research · 2016-05-05

Preclinical / mechanistic

27. Ketogenic diet decreases oxidative stress and improves mitochondrial respiratory complex activity.

Greco T, Glenn TC, Hovda DA, Prins ML · Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2015-10-13

Preclinical / mechanistic

28. Ketogenic diet prevents alterations in brain metabolism in young but not adult rats after traumatic brain injury.

Deng-Bryant Y, Prins ML, Hovda DA, Harris NG · Journal of neurotrauma · 2011-08-04

Preclinical / mechanistic

29. Intracisternal administration of glibenclamide or 5-hydroxydecanoate does not reverse the neuroprotective effect of ketogenic diet against ischemic brain injury-induced neurodegeneration.

Tai KK, Pham L, Truong DD · Brain injury · 2009-11-14

Randomized clinical trial

30. The protective effect of the ketogenic diet on traumatic brain injury-induced cell death in juvenile rats.

Hu ZG, Wang HD, Qiao L, Yan W, Tan QF, Yin HX · Brain injury · 2009-05-02

Preclinical / mechanistic

31. The effects of a ketogenic diet on behavioral outcome after controlled cortical impact injury in the juvenile and adult rat.

Appelberg KS, Hovda DA, Prins ML · Journal of neurotrauma · 2009-02-24

Preclinical / mechanistic

32. Ketogenic diet reduces cytochrome c release and cellular apoptosis following traumatic brain injury in juvenile rats.

Hu ZG, Wang HD, Jin W, Yin HX · Annals of clinical and laboratory science · 2009-02-10

Clinical trial / intervention

33. Neuroprotective and disease-modifying effects of the ketogenic diet.

Gasior M, Rogawski MA, Hartman AL · Behavioural pharmacology · 2006-08-31

Clinical trial / intervention

34. The Interplay between the Gut and Ketogenic Diets in Health and Disease.

Mu C, Rho JM, Shearer J · Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025-08-23

Cognitive Function Recent peer-reviewed literature

Source-audited selection from the connected PDF archive. Systematic reviews/meta-analyses and recent human evidence are prioritized when available; sparse areas are explicitly kept sparse.

Recent human evidence · 2026

1. Association Between Ketogenic Diet and Cognitive Function

Original publication title: Association Between Ketogenic Diet and Cognitive Function

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Human metabolic study

2. Two-Month Ketogenic Diet Alters Systemic and Brain Metabolism

Original publication title: Two-Month Ketogenic Diet Alters Systemic and Brain Metabolism

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Preclinical aging/cognition study

3. Ketogenic Diet Administration Later in Life Improves Memory

Original publication title: Ketogenic Diet Administration Later in Life Improves Memory

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Review

4. Bringing Nutritional Ketosis to the Table as an Option for Healing the Pediatric Brain

Original publication title: Bringing Nutritional Ketosis to the Table as an Option for Healing the Pediatric Brain

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Review

5. Dietary and Metabolic Approaches for Treating Cognitive Impairment Comorbid with Epilepsy

Original publication title: Dietary and Metabolic Approaches for Treating Cognitive Impairment Comorbid with Epilepsy

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Human mechanistic study

6. A Modified Mediterranean-Style Diet Enhances Brain Function via Specific Gut-Microbiome-Brain Mechanisms

Original publication title: A Modified Mediterranean-Style Diet Enhances Brain Function via Specific Gut-Microbiome-Brain Mechanisms

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Disease-focused review

7. The Role of a Ketogenic Diet in the Treatment of Dementia in Type 2 Diabetes Mellitus

Original publication title: The Role of a Ketogenic Diet in the Treatment of Dementia in Type 2 Diabetes Mellitus

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Systematic review

8. Ketogenic Interventions in Mild Cognitive Impairment, Alzheimer's Disease, and Parkinson's Disease: A Systematic Review and Critical Appraisal

Original publication title: Ketogenic Interventions in Mild Cognitive Impairment, Alzheimer's Disease, and Parkinson's Disease: A Systematic Review and Critical Appraisal

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Human comparative study

9. The Effect of a 2 Week Ketogenic Diet, versus a Carbohydrate-Based Diet, on Cognitive Performance, Mood and Subjective Sleepiness During 36 h of Extended Wakefulness in Military Personnel

Original publication title: The Effect of a 2 Week Ketogenic Diet, versus a Carbohydrate-Based Diet, on Cognitive Performance, Mood and Subjective Sleepiness During 36 h of Extended Wakefulness in Military Personnel

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Review

10. Emerging Nutrition Approaches to Support the Mind and Muscle for Healthy Aging

Original publication title: Emerging Nutrition Approaches to Support the Mind and Muscle for Healthy Aging

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Preclinical study

11. 2-Month Ketogenic Diet Preferentially Alters Skeletal Muscle and Augments Cognitive Function in Middle-Aged Female Mice

Original publication title: 2-Month Ketogenic Diet Preferentially Alters Skeletal Muscle and Augments Cognitive Function in Middle-Aged Female Mice

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Systematic review / meta-analysis

12. Effects of ketogenic diet on cognitive impairment in older adults: a systematic review and meta-analysis.

Xi L, Wan J, Hua Y, Guo M, Du J, Luo X, Yu H · Archives of gerontology and geriatrics · 2026-09-12

Clinical trial / intervention

13. From diet to drinking behavior: Ketogenic diet decreases ethanol intake in young adult female mice.

Torres-Rubio L, Mellado S, Montagud-Romero S, Pascual M, Rodríguez-Arias M · Behavioural brain research · 2026-09-05

Clinical trial / intervention

14. Epigenetic ageing is accelerated in drug-resistant epilepsy and dynamically modulated during ketogenic diet therapy.

Gervin K, Kverneland M, Nakken KO, Rudi K, Iversen PO, Selmer KK · EBioMedicine · 2026-08-22

Randomized clinical trial

15. Ketogenic effects of milk protein-coated medium-chain triglycerides in healthy men: A randomized, double-blind, crossover study.

Ito K, Kawasaki Y, Tamura K, Nakamura K, Kawai Y, Watanabe T · PloS one · 2026-08-10

Clinical trial / intervention

16. The ketogenic diet ameliorates behavioral abnormalities in a PTZ-induced zebrafish larvae model via modulating neurotransmitter balance.

Yang X, Lin J, Zhang Q, Xia Y, Zhou S, Wang Y, Li Q, Yu L · IBRO neuroscience reports · 2026-08-04

Randomized clinical trial

17. The effect of simultaneous application of plant-rich ketogenic diet and intermittent fasting on early-to-mid-stage Alzheimer's disease: a randomised controlled trial.

Tağraf B, Kaygusuz D, Yerlikaya D, Oğul ÖE, Hanoğlu L · The journal of nutrition, health & aging · 2026-07-24

Clinical trial / intervention

18. Ketogenic Diet-Mediated Immunomodulation for Prevention of Epilepsia Partialis Continua in Rasmussen's Encephalitis: Review and Case Study.

Salgado Rueda SA, Moreno Guerra N, Vargas Rojas JL · Case reports in neurology · 2026-07-10

Observational human study

19. Neurodevelopmental Risk Factors and Comparative Efficacy of Ketogenic Diet in Children With Spike-Wave Activation in Sleep: A Cohort Study.

Ma J, Wang J, Song X, Xie L, Li X, Hu Y, Hong S, Jiang L, Li T · Pediatric neurology · 2026-07-08

Systematic review / meta-analysis

20. Ketogenic diet therapies for the treatment of drug-resistant epilepsy in children and adults: A systematic review.

Vaccarezza MM, Sanguine VL, Balaciano G · PloS one · 2026-07-02

Randomized clinical trial

21. A fat chance at neuroprotection: Ketogenic diet and Parkinson's disease.

Hitawala G, Shulman LM · Clinical nutrition ESPEN · 2026-06-25

Systematic review / meta-analysis

22. Ketogenic diet therapy in pyruvate dehydrogenase deficiency: Global clinical practice from literature and survey data.

Madsen S, Allender B, Blackford R, Bollard T, Comerford A, Johnson ML, Sinha R, Vanatta L, Whiteley VJ, Schoeler NE, Ketogenic Dietitians Research Network · Molecular genetics and metabolism · 2026-06-18

Observational human study

23. Cognitive behavioral therapy for bipolar disorder: patient-level participation barriers and ketogenic metabolic therapy as a candidate adjunct.

Laurent N · Frontiers in psychology · 2026-06-15

Preclinical / mechanistic

24. Diet-Dependent Cognitive Benefits of Exogenous Ketone Body Precursor, (R,S)-1,3,-Butanediol, in a Mouse Model of Tauopathy.

Fulghum K, Hayir A, Ankeriasniemi R, Shaddy-Gouvion C, Vang CM, Salathe SF, Queathem ED, Hughey CC, Haeri M, Thyfault JP, Puchalska P, Crawford PA · bioRxiv : the preprint server for biology · 2026-06-08

Review

25. The Role of the Ketogenic Diet in Modulating Biochemical Pathophysiology in Psychiatric and Neurodegenerative Disorders.

Chang YB, Baleja JD · International journal of molecular sciences · 2026-05-29

Preclinical / mechanistic

26. Effects of Ketogenic Diet on Behavioral, Metabolic, and Peripheral Tissue Changes in a Propylthiouracil-Induced Hypothyroidism Model.

Akkaya EC, Ilgin R, Kızıldağ S, Argon A, Hoşgörler F · Medical principles and practice : international journal of the Kuwait University, Health Science Centre · 2026-05-08

Clinical trial / intervention

27. Ketogenic diet enhances cognitive-behavioral function and hippocampal neurogenesis while attenuating amyloid pathology in Tg-SwDI mice.

Pulido-Correa VE, Hernandez AV, Wind EJ, Zhu Y, Vogel C, Binu S, Jeneske M, Kuni D, Chiduruppa V, Echeverria B, Rosenberg L, Robison LS · Journal of Alzheimer's disease : JAD · 2026-05-04

Preclinical / mechanistic

28. From gut to brain: short-term ketogenic diet alleviates status epilepticus-induced cognitive deficits in rats.

Chen Y, Xu W, Hou Q, Jiang Y · Frontiers in physiology · 2026-04-28

Clinical trial / intervention

29. Ketogenic metabolic therapy: low-carbohydrate interventions as novel neuroprotective strategies for cognitive dysfunction in diabetes.

Xun Y, Zeng W · Frontiers in aging neuroscience · 2026-04-24

Preclinical / mechanistic

30. Ketogenic diet regulates Uch-L1(C) to improve cerebral energy metabolism and cognitive function in Alzheimer's disease mice.

Bao N, Zhang M, Tang M, Shen Z, Wang S, Jiang G · European journal of histochemistry : EJH · 2026-04-20

Preclinical / mechanistic

31. Ketogenic Diet Promotes Reward Learning by Upregulating Hippocampal CAMK2A Expression and Activating Dopamine Synaptic Signaling.

Qiao Y, Zeng Y, Chen C, Shen J, Wang Y, Pei P, Wang S · International journal of molecular sciences · 2026-04-17

Review

32. Ketogenic Diet in Children with Type 1 Diabetes: Parental Motivations and Potential Risks for Metabolic Health and Development.

Kovinthapillai R, Lan YY, Kędzia A, Niechciał E · Nutrients · 2026-04-15

Systematic review / meta-analysis

33. The effect of exogenous ketone bodies on cognition across health and disease: a systematic review and meta-analysis.

Bonnechère B, Stephens EB, Boileau AC, Ducker M, Stubbs BJ · Frontiers in nutrition · 2026-04-15

Clinical trial / intervention

34. Ketogenic interventions enhance REM sleep in females and support memory in aged rats.

Lark ARS, Mir FA, Ambareen N, Tian F, Carpenter AH, Crowley EA, Toro BA, Syme CE, Aygar S, Thendral A, Smith K, White CG, Mahamdeh MS, Choi J, Nehs CJ · Frontiers in aging neuroscience · 2026-04-10

Randomized clinical trial

35. A Ketogenic Diet for Treatment-Resistant Depression: A Randomized Clinical Trial.

Gao M, Kirk M, Knight H, Lash E, Michalopoulou M, Guess N, Stevens R, Browning M, Weich S, Burnet PWJ, Jebb SA, Aveyard P · JAMA psychiatry · 2026-04-01

Clinical trial / intervention

36. Ketogenic Diet and Brain Health: Cerebrovascular Mechanisms, Neuroprotection, and Translational Implications.

Mózes N, Fehér Á, Csípő T, Fazekas-Pongor V, Lipécz Á, Major D, Lehoczki A, Dósa N, Pártos K, Csík B, Yi HW, Kaposvári C, Horváth K, Fekete M · Nutrients · 2026-03-29

Randomized clinical trial

37. The Effects of 31-Day Exogenous Ketone Consumption on Running Performance, Cognitive Function, Metabolism, Body Composition, Hemodynamics, and Mood in Recreational Runners: A Randomized-Control Trial.

Prins PJ, Buga A, Storoschuk K, Buxton JD, Jenkins AK, Eklund CS, Dacey VC, Belitz SE, Sullivan RJ, Gerhart HD, D'Agostino DP, Volek JS, Koutnik AP · Journal of the American Nutrition Association · 2026-03-03

Observational human study

38. Glucose transporter type 1 deficiency syndrome: Phenotypes, molecular findings, and ketogenic therapy implementation in Argentina.

Armeno ML, Massaro M, Boccoli J, Caballero E, Chacon S, Diz M, Espeche A, Fasulo L, Galarza N, Gonzalez L, Kobayashi V, Loos M, Semprino M, Veneruzzo G, Verini A, Caraballo R · Epileptic disorders : international epilepsy journal with videotape · 2026-02-02

Clinical trial / intervention

39. Ketogenic diet improves cognitive impairment in rats with temporal lobe epilepsy by activating the Nrf2/HO-1/GPX4 signaling axis to inhibit ferroptosis.

Yang L, Wang J, Wang X, Li B, Zhao D, Li C, Li C, Cui Y, Chen Q, Yang Y, Gu J, Hou S, Zhang L, Qiang Y · Free radical biology & medicine · 2026-01-21

Clinical trial / intervention

40. Effect of a non-energy restricted ketogenic diet on cognition in sedentary healthy young adults.

Khattak M, Habib SH, Irfan M · Physiology international · 2026-01-20

Clinical trial / intervention

41. Complementary mechanisms of high-carbohydrate diets and ketogenic diets restore adult hippocampal neurogenesis and cognitive function in high-fat diet induced obesity in mice.

Kwon H, Seo DS, Ahmad Y, Park S, Yoo J, Lee J, Bae HJ, Jang Y · The Journal of nutritional biochemistry · 2025-12-29

Clinical trial / intervention

42. Ketogenic Diet Reduces Alcohol Consumption and Improves Memory and Sociability in Mice.

Bechard AR, Storie K, Grzeskowiak A, Forcier M, Nunez Y, Brambhatt D, Azurin S, Connell R, Kamel J · Journal of studies on alcohol and drugs · 2025-12-15

Randomized clinical trial

43. Metabolic Improvements with a Ketogenic Diet Correlate with Symptom Improvement in Psychosis: A Randomized Controlled Trial.

Abram SV, Kyner JM, Vu A, Naeem Z, Sethi S, Jacob MS, Fryer SL, Mathalon DH, Ford JM · Schizophrenia bulletin · 2025-11-25

Preclinical / mechanistic

44. A ketogenic diet improves memory in females in the APOE4 mouse model of Alzheimer's disease.

Di Lucente J, Rutkowsky JM, Errico Provenzano A, Persico G, Zhou Z, Jin LW, Ramsey JJ, Montgomery CB, Kim K, Giorgio M, Maezawa I, Cortopassi GA · GeroScience · 2025-11-24

Preclinical / mechanistic

45. Ketogenic Diets Alter the Gut Microbiome, Resulting in Decreased Susceptibility to and Cognitive Impairment in Rats with Pilocarpine-Induced Status Epilepticus.

Li B, Ma Y, Wang X, Zhao D, Wang Z, Wang G, Li C, Yang L, Ji H, Liu K, Chen Q, Yang Y, Ma W, Du J, Ma L, Zhang L, Qiang Y · Neurochemical research · 2024-06-27

Preclinical / mechanistic

46. Nifedipine Improves the Ketogenic Diet Effect on Insulin-Resistance-Induced Cognitive Dysfunction in Rats.

Abdel-Kareem NM, Elshazly SM, Abd El Fattah MA, Aldahish AA, Zaitone SA, Ali SK, Abd El-Haleim EA · Pharmaceuticals (Basel, Switzerland) · 2024-08-10

Other

47. Editorial: Ketogenic diets for cognitive and behavioral function.

de la Rubia Ortí JE, García-Pardo MP, Cuerda-Ballester M, Castellano-Estornell G, Benlloch M · Frontiers in nutrition · 2024-08-07

Preclinical / mechanistic

48. BETA-HYDROXYBUTYRATE COUNTERACTS THE DELETERIOUS EFFECTS OF A SATURATED HIGH-FAT DIET ON SYNAPTIC AMPA RECEPTORS AND COGNITIVE PERFORMANCE.

Rojas R, Griñán-Ferré C, Castellanos A, Griego E, Martínez M, Navarro-López JD, Jiménez-Díaz L, Rodríguez-Álvarez J, Del Cerro DS, Castillo PE, Pallàs M, Fadó R, Casals N · bioRxiv : the preprint server for biology · 2024-07-22

Preclinical / mechanistic

49. Ketogenic diet administration later in life improves memory by modifying the synaptic cortical proteome via the PKA signaling pathway in aging mice.

Acuña-Catalán D, Shah S, Wehrfritz C, Nomura M, Acevedo A, Olmos C, Quiroz G, Huerta H, Bons J, Ampuero E, Wyneken U, Sanhueza M, Arancibia F, Contreras D, Cárdenas JC, Morales B, Schilling B, Newman JC, González-Billault C · Cell reports. Medicine · 2024-06-05

Preclinical / mechanistic

50. Beta-Hydroxybutyrate Mitigates Sensorimotor and Cognitive Impairments in a Photothrombosis-Induced Ischemic Stroke in Mice.

Gureev AP, Sadovnikova IS, Chernyshova EV, Tsvetkova AD, Babenkova PI, Nesterova VV, Krutskikh EP, Volodina DE, Samoylova NA, Andrianova NV, Silachev DN, Plotnikov EY · International journal of molecular sciences · 2024-05-24

Randomized clinical trial

51. Addressing Pain Using a Mediterranean Ketogenic Nutrition Program in Older Adults with Mild Cognitive Impairment.

Klejc K, Cruz-Almeida Y, Sheffler JL · Journal of pain research · 2024-05-23

Preclinical / mechanistic

52. The impact of continuous and intermittent ketogenic diets on cognitive behavior, motor function, and blood lipids in TgF344-AD rats.

Rutkowsky JM, Roland Z, Valenzuela A, Nguyen AB, Park HH, Six N, Dursun I, Kim K, Lein PJ, Ramsey JJ · Aging · 2024-04-12

Clinical trial / intervention

53. A Ketogenic Diet may Improve Cognitive Function in Rats with Temporal Lobe Epilepsy by Regulating Endoplasmic Reticulum Stress and Synaptic Plasticity.

Qiao Q, Tian S, Zhang Y, Che L, Li Q, Qu Z, Wang W · Molecular neurobiology · 2023-10-23

Preclinical / mechanistic

54. Ketogenic diet attenuates cognitive dysfunctions induced by hypoglycemia via inhibiting endoplasmic reticulum stress-dependent pathways.

Li C, Ma Y, Chai X, Feng X, Feng W, Zhao Y, Cui C, Wang J, Zhao S, Zhu X · Food & function · 2024-02-05

Clinical trial / intervention

55. A long-term ketogenic diet in young and aged rats has dissociable effects on prelimbic cortex and CA3 ensemble activity.

Hernandez AR, Barrett ME, Lubke KN, Maurer AP, Burke SN · Frontiers in aging neuroscience · 2023-12-14

Clinical trial / intervention

56. Ketogenic therapies in Parkinson's disease, Alzheimer's disease, and mild cognitive impairment: An integrative review.

Price S, Ruppar TM · Applied nursing research : ANR · 2023-10-28

Clinical trial / intervention

57. Ketogenic diet alleviates cognitive dysfunction and neuroinflammation in APP/PS1 mice via the Nrf2/HO-1 and NF-κB signaling pathways.

Jiang J, Pan H, Shen F, Tan Y, Chen S · Neural regeneration research · 2023-07-14

Systematic review / meta-analysis

58. Effects of the ketogenic diet on cognition: a systematic review.

Chinna-Meyyappan A, Gomes FA, Koning E, Fabe J, Breda V, Brietzke E · Nutritional neuroscience · 2022-11-10

Preclinical / mechanistic

59. Ketogenic diet alleviates brain iron deposition and cognitive dysfunction via Nrf2-mediated ferroptosis pathway in APP/PS1 mouse.

Qin Y, Bai D, Tang M, Zhang M, Zhao L, Li J, Yang R, Jiang G · Brain research · 2023-05-08

Clinical trial / intervention

60. Ketogenic diets initiated in late mid-life improved measures of spatial memory in male mice.

Zhou Z, Kim K, Ramsey JJ, Rutkowsky JM · GeroScience · 2023-03-18

Randomized clinical trial

61. The effect of a 2 week ketogenic diet, versus a carbohydrate-based diet, on cognitive performance, mood and subjective sleepiness during 36 h of extended wakefulness in military personnel: An exploratory study.

Henderson LR, van den Berg M, Shaw DM · Journal of sleep research · 2023-02-03

Case report / case series

62. Timing of Ketogenic Dietary Therapy (KDT) Introduction and Its Impact on Cognitive Profiles in Children with Glut1-DS-A Preliminary Study.

Barthold M, Jurkutat A, Goetz R, Schubring L, Spiegler J, Fries AS, Kiesel L, Klepper J · Children (Basel, Switzerland) · 2023-04-03

Systematic review / meta-analysis

63. Correction to: Ketogenic diet and cognition in neurological diseases: a systematic review.

Nutrition reviews · 2022-06-29

Systematic review / meta-analysis

64. Mediterranean Diet, Ketogenic Diet or MIND Diet for Aging Populations with Cognitive Decline: A Systematic Review.

Devranis P, Vassilopoulou Ε, Tsironis V, Sotiriadis PM, Chourdakis M, Aivaliotis M, Tsolaki M · Life (Basel, Switzerland) · 2023-01-06

Randomized clinical trial

65. Small extracellular vesicles in plasma reveal molecular effects of modified Mediterranean-ketogenic diet in participants with mild cognitive impairment.

Kumar A, Sharma M, Su Y, Singh S, Hsu FC, Neth BJ, Register TC, Blennow K, Zetterberg H, Craft S, Deep G · Brain communications · 2022-10-19

Randomized clinical trial

66. Ketone Ester Supplementation Improves Some Aspects of Cognitive Function during a Simulated Soccer Match after Induced Mental Fatigue.

Quinones MD, Lemon PWR · Nutrients · 2022-10-19

Preclinical / mechanistic

67. Cognitive profile of male mice exposed to a Ketogenic Diet.

Ródenas-González F, Blanco-Gandía MC, Miñarro J, Rodríguez-Arias M · Physiology & behavior · 2022-06-15

Clinical trial / intervention

68. Ketogenic dietary lifestyle intervention effects on sleep, cognition, and behavior in mild cognitive impairment: Study design.

Sanderlin AH, Hayden KM, Baker LD, Craft S · Alzheimer's & dementia (New York, N. Y.) · 2022-09-14

Systematic review / meta-analysis

69. Ketogenic diet, epilepsy and cognition: what do we know so far? A systematic review.

Lima MC, Gabiatti MP, Moreira JD, Ribeiro LC, Lunardi MDS, Lin K, Venske DK · Nutrition reviews · 2022-05-11

Systematic review / meta-analysis

70. Ketogenic diet for epilepsy: an overview of systematic review and meta-analysis.

Ruan Y, Chen L, She D, Chung Y, Ge L, Han L · European journal of clinical nutrition · 2022-01-13

Randomized clinical trial

71. Cognitive, Sleep, and Autonomic Responses to Induction of a Ketogenic Diet in Military Personnel: A Pilot Study.

Shaw DM, Henderson L, van den Berg M · Aerospace medicine and human performance · 2022-06-22

Review

72. Comparison of the Impact of the Mediterranean Diet, Anti-Inflammatory Diet, Seventh-Day Adventist Diet, and Ketogenic Diet Relative to Cognition and Cognitive Decline.

To J, Shao ZY, Gandawidjaja M, Tabibi T, Grysman N, Grossberg GT · Current nutrition reports · 2022-03-26

Clinical trial / intervention

73. Effects of ketogenic diet on cognitive functions of mice fed high-fat-high-cholesterol diet.

Lin DT, Kao NJ, Cross TL, Lee WJ, Lin SH · The Journal of nutritional biochemistry · 2022-02-20

Review

74. The Effect of the Ketogenic Diet on the Therapy of Neurodegenerative Diseases and Its Impact on Improving Cognitive Functions.

Grochowska K, Przeliorz A · Dementia and geriatric cognitive disorders extra · 2022-05-30

Case report / case series

75. Positive impact of a modified Atkins diet on cognition, seizure control, and abnormal movements in an adult with glucose transporter type 1 deficiency syndrome: case report.

Diaz-Arias LA, Henry-Barron BJ, Buchholz A, Cervenka MC · Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2022-03-03

Clinical trial / intervention

76. Ketogenic diet ameliorates cognitive impairment and neuroinflammation in a mouse model of Alzheimer's disease.

Xu Y, Jiang C, Wu J, Liu P, Deng X, Zhang Y, Peng B, Zhu Y · CNS neuroscience & therapeutics · 2021-12-10

Preclinical / mechanistic

77. A comparative study of the effect of a gentle ketogenic diet containing medium-chain or long-chain triglycerides on chronic sleep deprivation-induced cognitive deficiency.

Wang X, Yang Y, Xiao A, Zhang N, Miao M, Wang Z, Han J, Wen M · Food & function · 2022-02-21

Randomized clinical trial

78. Ketone Ester Effects on Biomarkers of Brain Metabolism and Cognitive Performance in Cognitively Intact Adults ≥ 55 Years Old. A Study Protocol for a Double-Blinded Randomized Controlled Clinical Trial.

Avgerinos KI, Mullins RJ, Egan JM, Kapogiannis D · The journal of prevention of Alzheimer's disease · 2022-01-31

Randomized clinical trial

79. A ketogenic supplement improves white matter energy supply and processing speed in mild cognitive impairment.

Roy M, Fortier M, Rheault F, Edde M, Croteau E, Castellano CA, Langlois F, St-Pierre V, Cuenoud B, Bocti C, Fulop T, Descoteaux M, Cunnane SC · Alzheimer's & dementia (New York, N. Y.) · 2021-11-17

Preclinical / mechanistic

80. Alterations in the gut microbiota contribute to cognitive impairment induced by the ketogenic diet and hypoxia.

Olson CA, Iñiguez AJ, Yang GE, Fang P, Pronovost GN, Jameson KG, Rendon TK, Paramo J, Barlow JT, Ismagilov RF, Hsiao EY · Cell host & microbe · 2021-08-05

Systematic review / meta-analysis

81. The Efficacy of Ketogenic Therapies in the Clinical Management of People with Neurodegenerative Disease: A Systematic Review.

Dewsbury LS, Lim CK, Steiner GZ · Advances in nutrition (Bethesda, Md.) · 2020-08-24

Randomized clinical trial

82. An fMRI Investigation into the Effects of Ketogenic Medium-Chain Triglycerides on Cognitive Function in Elderly Adults: A Pilot Study.

Yomogida Y, Matsuo J, Ishida I, Ota M, Nakamura K, Ashida K, Kunugi H · Nutrients · 2021-06-22

Systematic review / meta-analysis

83. Ketogenic diet and cognition in neurological diseases: a systematic review.

Pavón S, Lázaro E, Martínez O, Amayra I, López-Paz JF, Caballero P, Al-Rashaida M, Luna PM, García M, Pérez M, Berrocoso S, Rodríguez AA, Pérez-Núñez P · Nutrition reviews · 2020-12-24

Preclinical / mechanistic

84. Effects of ketogenic diet on cognitive function in pentylenetetrazol-kindled rats.

Wang X, Huang S, Liu Y, Li D, Dang Y, Yang L · Epilepsy research · 2020-12-10

Clinical trial / intervention

85. Ketogenic Diet for the Treatment and Prevention of Dementia: A Review.

Davis JJ, Fournakis N, Ellison J · Journal of geriatric psychiatry and neurology · 2020-01-30

Systematic review / meta-analysis

86. To Keto or Not to Keto? A Systematic Review of Randomized Controlled Trials Assessing the Effects of Ketogenic Therapy on Alzheimer Disease.

Grammatikopoulou MG, Goulis DG, Gkiouras K, Theodoridis X, Gkouskou KK, Evangeliou A, Dardiotis E, Bogdanos DP · Advances in nutrition (Bethesda, Md.) · 2019-12-26

Clinical trial / intervention

87. Nutritional Ketosis and photobiomodulation remediate mitochondria warding off Alzheimer's disease in a diabetic, ApoE4+ patient with mild cognitive impairment: A case report.

Horner S, Berger L, Gibas K · Photodiagnosis and photodynamic therapy · 2020-04-16

Preclinical / mechanistic

88. Male mice placed on a ketogenic diet from postnatal day (P) 21 through adulthood have reduced growth, are hypoactive, show increased freezing in a conditioned fear paradigm, and have spatial learning deficits.

Miles KN, Skelton MR · Brain research · 2020-01-31

Randomized clinical trial

89. Cognitive Effects of a Ketogenic Diet on Neurocognitive Impairment in Adults Aging With HIV: A Pilot Study.

Morrison SA, Fazeli PL, Gower B, Willig AL, Younger J, Sneed NM, Vance DE · The Journal of the Association of Nurses in AIDS Care : JANAC · 2019-11-15

Systematic review / meta-analysis

90. Are ketogenic diets promising for Alzheimer's disease? A translational review.

Lilamand M, Porte B, Cognat E, Hugon J, Mouton-Liger F, Paquet C · Alzheimer's research & therapy · 2020-04-14

Review

91. Influence of the Mediterranean and Ketogenic Diets on Cognitive Status and Decline: A Narrative Review.

Vinciguerra F, Graziano M, Hagnäs M, Frittitta L, Tumminia A · Nutrients · 2020-04-08

Review

92. Glucose transporter type 1 deficiency syndrome and the ketogenic diet.

Schwantje M, Verhagen LM, van Hasselt PM, Fuchs SA · Journal of inherited metabolic disease · 2019-11-13

Clinical trial / intervention

93. Modified ketogenic diet is associated with improved cerebrospinal fluid biomarker profile, cerebral perfusion, and cerebral ketone body uptake in older adults at risk for Alzheimer's disease: a pilot study.

Neth BJ, Mintz A, Whitlow C, Jung Y, Solingapuram Sai K, Register TC, Kellar D, Lockhart SN, Hoscheidt S, Maldjian J, Heslegrave AJ, Blennow K, Cunnane SC, Castellano CA, Zetterberg H, Craft S · Neurobiology of aging · 2019-09-26

Clinical trial / intervention

94. Nutritional ketosis for mild cognitive impairment in Parkinson's disease: A controlled pilot trial.

Krikorian R, Shidler MD, Summer SS, Sullivan PG, Duker AP, Isaacson RS, Espay AJ · Clinical parkinsonism & related disorders · 2019-08-06

Randomized clinical trial

95. Three consecutive weeks of nutritional ketosis has no effect on cognitive function, sleep, and mood compared with a high-carbohydrate, low-fat diet in healthy individuals: a randomized, crossover, controlled trial.

Iacovides S, Goble D, Paterson B, Meiring RM · The American journal of clinical nutrition · 2018-11-29

Randomized clinical trial

96. A ketogenic drink improves brain energy and some measures of cognition in mild cognitive impairment.

Fortier M, Castellano CA, Croteau E, Langlois F, Bocti C, St-Pierre V, Vandenberghe C, Bernier M, Roy M, Descoteaux M, Whittingstall K, Lepage M, Turcotte ÉE, Fulop T, Cunnane SC · Alzheimer's & dementia : the journal of the Alzheimer's Association · 2019-04-23

Clinical trial / intervention

97. Ketogenic diet rescues cognition in ApoE4+ patient with mild Alzheimer's disease: A case study.

Morrill SJ, Gibas KJ · Diabetes & metabolic syndrome · 2019-01-24

Randomized clinical trial

98. Effects of a medium-chain triglyceride-based ketogenic formula on cognitive function in patients with mild-to-moderate Alzheimer's disease.

Ota M, Matsuo J, Ishida I, Takano H, Yokoi Y, Hori H, Yoshida S, Ashida K, Nakamura K, Takahashi T, Kunugi H · Neuroscience letters · 2018-10-24

Randomized clinical trial

99. Intermittent Running and Cognitive Performance after Ketone Ester Ingestion.

Evans M, Egan B · Medicine and science in sports and exercise · 2018-06-27

Systematic review / meta-analysis

100. Cognitive benefits of the ketogenic diet in patients with epilepsy: A systematic overview.

van Berkel AA, IJff DM, Verkuyl JM · Epilepsy & behavior : E&B · 2018-08-31

Clinical trial / intervention

101. Ketogenic diet, high intensity interval training (HIIT) and memory training in the treatment of mild cognitive impairment: A case study.

Dahlgren K, Gibas KJ · Diabetes & metabolic syndrome · 2018-04-11

Observational human study

102. Ketogenic diet effects on 52 children with pharmacoresistant epileptic encephalopathy: A clinical prospective study.

Wu Q, Wang H, Fan YY, Zhang JM, Liu XY, Fang XY, Yang FH, Cao QJ, Qi Y · Brain and behavior · 2018-04-18

Randomized clinical trial

103. [Epilepsy, cognition and ketogenic diet].

Garcia-Penas JJ · Revista de neurologia · 2018-03-09

Randomized clinical trial

104. The ketogenic diet as a non-pharmacological treatment for HIV-associated neurocognitive disorder: A descriptive analysis.

Morrison SA, Fazeli PL, Gower B, Younger J, Willig A, Sneed NM, Vance DE · Journal of psychiatry and behavioral science · 2018-11-06

Other

105. Ageing: Improvement in age-related cognitive functions and life expectancy by ketogenic diets.

Astrup A, Hjorth MF · Nature reviews. Endocrinology · 2017-11-10

Other

106. Development and pilot testing of a parent-reported health-related quality of life measure for children on the ketogenic diet: The KetoQoL.

Barwick K, Parker T, Murphy N, Todd A, Leveritt M, Wilkinson SA · Nutrition & dietetics : the journal of the Dietitians Association of Australia · 2017-04-12

Preclinical / mechanistic

107. The ketogenic diet affects the social behavior of young male rats.

Kasprowska-Liśkiewicz D, Liśkiewicz AD, Nowacka-Chmielewska MM, Nowicka J, Małecki A, Barski JJ · Physiology & behavior · 2017-06-13

Preclinical / mechanistic

108. Ketogenic Diet Reduces Midlife Mortality and Improves Memory in Aging Mice.

Newman JC, Covarrubias AJ, Zhao M, Yu X, Gut P, Ng CP, Huang Y, Haldar S, Verdin E · Cell metabolism · 2017-01-23

Preclinical / mechanistic

109. Sex-Specific Life Course Changes in the Neuro-Metabolic Phenotype of Glut3 Null Heterozygous Mice: Ketogenic Diet Ameliorates Electroencephalographic Seizures and Improves Sociability.

Dai Y, Zhao Y, Tomi M, Shin BC, Thamotharan S, Mazarati A, Sankar R, Wang EA, Cepeda C, Levine MS, Zhang J, Frew A, Alger JR, Clark PM, Sondhi M, Kositamongkol S, Leibovitch L, Devaskar SU · Endocrinology · 2016-11-03

Clinical trial / intervention

110. A ketogenic diet rescues hippocampal memory defects in a mouse model of Kabuki syndrome.

Benjamin JS, Pilarowski GO, Carosso GA, Zhang L, Huso DL, Goff LA, Vernon HJ, Hansen KD, Bjornsson HT · Proceedings of the National Academy of Sciences of the United States of America · 2016-12-20

Other

111. Effect of a ketogenic meal on cognitive function in elderly adults: potential for cognitive enhancement.

Ota M, Matsuo J, Ishida I, Hattori K, Teraishi T, Tonouchi H, Ashida K, Takahashi T, Kunugi H · Psychopharmacology · 2016-08-27

Preclinical / mechanistic

112. Ketogenic diet attenuates spatial and item memory impairment in pentylenetetrazol-kindled rats.

Jiang Y, Lu Y, Jia M, Wang X, Zhang Z, Hou Q, Wang B · Brain research · 2016-06-22

Preclinical / mechanistic

113. Erratum to: Environmental Enrichment Mitigates Detrimental Cognitive Effects of Ketogenic Diet in Weanling Rats.

Scichilone JM, Yarraguntla K, Charalambides A, Harney JP, Butler D · Journal of molecular neuroscience : MN · 2016-06-21

Preclinical / mechanistic

114. Environmental Enrichment Mitigates Detrimental Cognitive Effects of Ketogenic Diet in Weanling Rats.

Scichilone JM, Yarraguntla K, Charalambides A, Harney JP, Butler D · Journal of molecular neuroscience : MN · 2016-04-25

Preclinical / mechanistic

115. Ketogenic diet change cPLA2/clusterin and autophagy related gene expression and correlate with cognitive deficits and hippocampal MFs sprouting following neonatal seizures.

Ni H, Zhao DJ, Tian T · Epilepsy research · 2015-12-03

Other

116. The Effects of Ketogenic Diet on Seizures, Cognitive Functions, and Other Neurological Disorders in Classical Phenotype of Glucose Transporter 1 Deficiency Syndrome.

Gumus H, Bayram AK, Kardas F, Canpolat M, Çağlayan AO, Kumandas S, Kendirci M, Per H · Neuropediatrics · 2015-08-12

Case report / case series

117. Cognitive outcomes in febrile infection-related epilepsy syndrome treated with the ketogenic diet.

Singh RK, Joshi SM, Potter DM, Leber SM, Carlson MD, Shellhaas RA · Pediatrics · 2014-10-22

Other

118. Does ketogenic diet improve cognitive function in patients with GLUT1-DS? A 6- to 17-month follow-up study.

Ramm-Pettersen A, Stabell KE, Nakken KO, Selmer KK · Epilepsy & behavior : E&B · 2014-09-18

Preclinical / mechanistic

119. Ketogenic diet improves motor performance but not cognition in two mouse models of Alzheimer's pathology.

Brownlow ML, Benner L, D'Agostino D, Gordon MN, Morgan D · PloS one · 2013-09-12

Observational human study

120. Movement disorders in GLUT1 deficiency syndrome respond to the modified Atkins diet.

Leen WG, Mewasingh L, Verbeek MM, Kamsteeg EJ, van de Warrenburg BP, Willemsen MA · Movement disorders : official journal of the Movement Disorder Society · 2013-06-25

Preclinical / mechanistic

121. A ketone ester diet exhibits anxiolytic and cognition-sparing properties, and lessens amyloid and tau pathologies in a mouse model of Alzheimer's disease.

Kashiwaya Y, Bergman C, Lee JH, Wan R, King MT, Mughal MR, Okun E, Clarke K, Mattson MP, Veech RL · Neurobiology of aging · 2012-12-29

Preclinical / mechanistic

122. Triheptanoin supplementation to ketogenic diet curbs cognitive impairment in APP/PS1 mice used as a model of familial Alzheimer's disease.

Aso E, Semakova J, Joda L, Semak V, Halbaut L, Calpena A, Escolano C, Perales JC, Ferrer I · Current Alzheimer research · 2012-04-04

Other

123. Ketogenic diet effects on cognition, mood, and psychosocial adjustment in children.

Lambrechts DA, Bovens MJ, de la Parra NM, Hendriksen JG, Aldenkamp AP, Majoie MJ · Acta neurologica Scandinavica · 2012-06-12

Clinical trial / intervention

124. The effects of the ketogenic diet on behavior and cognition.

Hallböök T, Ji S, Maudsley S, Martin B · Epilepsy research · 2011-08-27

Preclinical / mechanistic

125. Inflammation-mediated memory dysfunction and effects of a ketogenic diet in a murine model of multiple sclerosis.

Kim DY, Hao J, Liu R, Turner G, Shi FD, Rho JM · PloS one · 2012-05-02

Preclinical / mechanistic

126. A ketogenic diet delays weight loss and does not impair working memory or motor function in the R6/2 1J mouse model of Huntington's disease.

Ruskin DN, Ross JL, Kawamura M, Ruiz TL, Geiger JD, Masino SA · Physiology & behavior · 2011-04-09

Preclinical / mechanistic

127. The effects of a ketogenic diet on behavioral outcome after controlled cortical impact injury in the juvenile and adult rat.

Appelberg KS, Hovda DA, Prins ML · Journal of neurotrauma · 2009-02-24

Other

128. The importance of parental expectations of cognitive improvement for their children with epilepsy prior to starting the ketogenic diet.

Farasat S, Kossoff EH, Pillas DJ, Rubenstein JE, Vining EP, Freeman JM · Epilepsy & behavior : E&B · 2006-01-30

Preclinical / mechanistic

129. Claims to identify detrimental effects of the ketogenic diet (KD) on cognitive function in rats.

Cunnane SC, Likhodii SS · Pediatric research · 2004-08-19

Randomized clinical trial

130. Cognitive effects of ketogenic weight-reducing diets.

Wing RR, Vazquez JA, Ryan CM · International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity · 1995-11-01

Clinical trial / intervention

131. Mechanisms of a Ketogenic Diet and High-Carbohydrate Diets on Cognitive Impairment and the Microbiota-Gut-Brain Axis.

Shang W, Gu Z, Li L, Cheng L, Hong Y · Nutrition reviews · 2025-10-30

Systematic review / meta-analysis

132. The Effect of Exogenous Ketone Bodies on Cognition in Patients with Mild Cognitive Impairment, Alzheimer's Disease and in Healthy Adults: A Systematic Review and Meta-Analysis.

Bonnechère B, Stephens EB, Boileau AC, Ducker M, Stubbs BJ · medRxiv : the preprint server for health sciences · 2025-09-18

Preclinical / mechanistic

133. Ketogenic Diet Mitigates Age-Related Cognitive Decline and Neuroinflammation in Rats, While Antibiotics Exacerbate Brain Health Risks.

Sayin O, Ilgin R, Akkaya EC, Ates M, Hosgorler F · Journal of molecular neuroscience : MN · 2025-09-10

Preclinical / mechanistic

134. Beta-hydroxybutyrate counteracts the deleterious effects of a saturated high-fat diet on synaptic AMPAR receptors and cognitive performance.

Rojas R, Griñán-Ferré C, Castellanos A, Griego E, Martínez M, de Dios Navarro-López J, Jiménez-Díaz L, Rodríguez-Álvarez J, Soto Del Cerro D, Castillo PE, Pallàs M, Casals N, Fadó R · Molecular metabolism · 2025-07-06

Randomized clinical trial

135. Ginkgo ketone ester tablets for the treatment of cognitive impairment associated with chemotherapy for breast cancer - a prospective cohort study.

Chen J, Chen L, Jiang K, Wang D, Wu C, Qin Y, Liu S · Frontiers in pharmacology · 2025-07-21

Preclinical / mechanistic

136. Ramipril and ketogenic diet response in cognitive dysfunction of insulin-resistant rats.

Abdel-Kareem NM, Elshazly SM, Abd El Fattah MA, Zaitone SA, Elmasry TA, Saleh A, Abd El-Haleim EA · Frontiers in pharmacology · 2025-07-11

Preclinical / mechanistic

137. Protective Effects of the Ketogenic Diet on Cognitive Impairment Induced by Status Epilepticus in Rats: Modulation of Neuroinflammation Through the NF-κB Signaling Pathway.

Wang W, Wang L, Jiang C, Zhang S, Tan C, Peng L, Ding R, Tian B, Song X, Jiang L · Pediatric discovery · 2025-06-23

Randomized clinical trial

138. Ketone ester ingestion impairs exercise performance without impacting cognitive function or circulating EPO during acute hypoxic exposure.

Stalmans M, Tominec D, Lauriks W, Robberechts R, Ramaekers M, Debevec T, Poffé C · Journal of applied physiology (Bethesda, Md. : 1985) · 2025-05-02

Clinical trial / intervention

139. Cognitive and behavioral impact of antiseizure medications, neuromodulation, ketogenic diet, and surgery in Lennox-Gastaut syndrome: A comprehensive review.

Samanta D · Epilepsy & behavior : E&B · 2025-01-23

Systematic review / meta-analysis

140. Efficacy and Safety of Exogenous Ketones in People with Mild Neurocognitive Disorder and Alzheimer's Disease: A Systematic Literature Review.

Krolak-Salmon P, Swerdlow RH, Mastain T, Dive-Pouletty C, Pooley N, Kisomi M · Nutrition reviews · 2025-02-12

Randomized clinical trial

141. Effects of Ketone Ester Supplementation on Cognition and Appetite in Individuals with and Without Metabolic syndrome: A Randomized Trial.

Graybeal AJ, Aultman RS, Brandner CF, Vallecillo-Bustos A, Compton AT, Swafford SH, Newsome TA, Stavres J · Journal of dietary supplements · 2025-03-04

Headache & Migraine Recent peer-reviewed literature

Source-audited selection from the connected PDF archive. Systematic reviews/meta-analyses and recent human evidence are prioritized when available; sparse areas are explicitly kept sparse.

Recent review · 2025

1. The Hypometabolic State of the Migraine Brain: Is a Ketogenic Diet the Answer?

Original publication title: The Hypometabolic State of the Migraine Brain: Is a Ketogenic Diet the Answer?

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Recent review · 2025

2. Impact of Dietary Patterns on Migraine Management: Mechanisms of Action and Recent Evidence

Original publication title: Impact of Dietary Patterns on Migraine Management: Mechanisms of Action and Recent Evidence

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Human clinical evidence · 2025

3. The Long-Term Treatment of Drug-Resistant Migraine with a Ketogenic Diet

Original publication title: The Long-Term Treatment of Drug-Resistant Migraine with a Ketogenic Diet

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Human clinical study

4. Ketogenic Diet Improves Sleep Quality and Daytime Sleepiness in Chronic Migraine

Original publication title: Ketogenic Diet Improves Sleep Quality and Daytime Sleepiness in Chronic Migraine

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Human clinical study

5. Mediterranean Ketogenic Diet Accounts for Reduced Pain Frequency in Migraine

Original publication title: Mediterranean Ketogenic Diet Accounts for Reduced Pain Frequency in Migraine

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Human comparative study

6. The Effect of Three Different Ketogenic Diet Protocols on Migraine and Fatigue in Chronic and High-Frequency Episodic Migraine

Original publication title: The Effect of Three Different Ketogenic Diet Protocols on Migraine and Fatigue in Chronic and High-Frequency Episodic Migraine

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Randomized controlled trial

7. Very-Low-Calorie Ketogenic Diet vs Hypocaloric Balanced Diet in the Prevention of High-Frequency Episodic Migraine: The EMIKETO Randomized Controlled Trial

Original publication title: Very-Low-Calorie Ketogenic Diet vs Hypocaloric Balanced Diet in the Prevention of High-Frequency Episodic Migraine: The EMIKETO Randomized Controlled Trial

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Retrospective human study

8. Ketogenic Diet and Low-Glycemic-Index Diet for Chronic and Episodic Migraine: A Real-Life Retrospective Study

Original publication title: Ketogenic Diet and Low-Glycemic-Index Diet for Chronic and Episodic Migraine: A Real-Life Retrospective Study

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Review · 2025

9. Dietary Patterns and Migraine: Insights and Impact

Original publication title: Dietary Patterns and Migraine: Insights and Impact

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Human clinical evidence · 2025

10. The Long-Term Treatment of Drug-Resistant Migraine with Ketogenic Dietary Therapy

Original publication title: The Long-Term Treatment of Drug-Resistant Migraine with Ketogenic Dietary Therapy

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Clinical / hypothesis evidence · 2024

11. Specifically Formulated Ketogenic, Low-Carbohydrate, and Carnivore Diets Can Prevent Migraine

Original publication title: Specifically Formulated Ketogenic, Low-Carbohydrate, and Carnivore Diets Can Prevent Migraine

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Randomized controlled trial · 2023

12. Very-Low-Calorie Ketogenic Diet versus Hypocaloric Balanced Diet in the Prevention of High-Frequency Episodic Migraine: The EMIKETO Randomized Controlled Trial

Original publication title: Very-Low-Calorie Ketogenic Diet versus Hypocaloric Balanced Diet in the Prevention of High-Frequency Episodic Migraine: The EMIKETO Randomized Controlled Trial

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Retrospective human study · 2023

13. Ketogenic Diet and Low-Glycemic-Index Diet for the Treatment of Chronic and Episodic Migraine: A Single-Center Real-Life Retrospective Study

Original publication title: Ketogenic Diet and Low-Glycemic-Index Diet for the Treatment of Chronic and Episodic Migraine: A Single-Center Real-Life Retrospective Study

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Systematic review & meta-analysis · 2023

14. Ketosis and Migraine: A Systematic Review of the Literature and Meta-Analysis

Original publication title: Ketosis and Migraine: A Systematic Review of the Literature and Meta-Analysis

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Case report · 2023

15. Nummular Headache: A Case Report of Remission Following Ketogenic Diet and Botulinum Toxin Type A Injections

Original publication title: Nummular Headache: A Case Report of Remission Following Ketogenic Diet and Botulinum Toxin Type A Injections

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Mechanistic review

16. Pathophysiological Abnormalities in Migraine Ameliorated by Ketosis

Original publication title: Pathophysiological Abnormalities in Migraine Ameliorated by Ketosis

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Clinical trial

17. Efficacy of Modified Atkins Ketogenic Diet in Chronic Cluster Headache: An Open-Label, Single-Arm Clinical Trial

Original publication title: Efficacy of Modified Atkins Ketogenic Diet in Chronic Cluster Headache: An Open-Label, Single-Arm Clinical Trial

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Human clinical evidence

18. Migraine Prevention through Ketogenic Diet: More than Body Weight Reduction

Original publication title: Migraine Prevention through Ketogenic Diet: More than Body Weight Reduction

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Case series

19. Diet Transiently Improves Migraine in Two Twin Sisters: Possible Role of Ketogenesis

Original publication title: Diet Transiently Improves Migraine in Two Twin Sisters: Possible Role of Ketogenesis

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Clinical recommendations

20. Applications of Ketogenic Diets in Patients with Headache: Clinical Recommendations

Original publication title: Applications of Ketogenic Diets in Patients with Headache: Clinical Recommendations

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Observational human study

21. The Long-Term Treatment of Drug-Resistant Migraine with the Modified Atkins Ketogenic Diet: A Single-Center, Retrospective Study.

Francini-Pesenti F, Favaretto S, D'Angelo M, Cacciapuoti M, Calò LA · Nutrients · 2024-12-15

Other

22. Letter to the editor - "Mediterranean ketogenic diet accounts for reduced pain frequency and intensity in patients with chronic migraine: A pilot study".

Souza APDS, Luclécia da Silva M, Almeida Barros WM · Clinical nutrition (Edinburgh, Scotland) · 2024-10-05

Other

23. A 1-month ketogenic diet in patients with migraine gives a clinical beneficial effect associated with increased latency of somatosensory thalamo-cortical activity.

Abagnale C, Sebastianelli G, Casillo F, Di Renzo A, Parisi V, Cioffi E, Serrao M, Schoenen J, Coppola G, Di Lorenzo C · Clinical neurophysiology practice · 2024-11-15

Other

24. Ketogenic Diet Improves Sleep Quality and Daytime Sleepiness in Chronic Migraine: A Pilot Study.

Tereshko Y, Dal Bello S, Belgrado E, Di Lorenzo C, Pittino A, Filippi F, Valdemarin F, Lettieri C, Gigli GL, Nilo A, Pellitteri G, Merlino G, Valente M · Neurology international · 2024-10-25

Clinical trial / intervention

25. Mediterranean ketogenic diet accounts for reduced pain frequency and intensity in patients with chronic migraine: A pilot study.

Olivito I, Simona F, Tarsitano A, Pagliuso M, Tarantino C, De Lorenzo A, Alò R, Avolio E, Facciolo RM · Clinical nutrition (Edinburgh, Scotland) · 2024-06-19

Clinical trial / intervention

26. CGRP Antagonism and Ketogenic Diet in the Treatment of Migraine.

Finelli F, Catalano A, De Lisa M, Ferraro GA, Genovese S, Giuzio F, Salvia R, Scieuzo C, Sinicropi MS, Svolacchia F, Vassallo A, Santarsiere A, Saturnino C · Medicina (Kaunas, Lithuania) · 2024-01-15

Observational human study

27. Sleep effects of Ketogenic diet in pediatric patients with migraine: Preliminary data of a prospective study.

Pasca L, Toni F, Fassio F, Dogliani S, Genta S, Grumi S, Sammartano A, Vitali H, Capriglia E, Tagliabue A, Guglielmetti M, De Giorgis V, Carpani A, Terzaghi M · Sleep medicine · 2023-12-07

Clinical trial / intervention

28. The Ketogenic Diet in the Prevention of Migraines in the Elderly.

Fila M, Chojnacki J, Pawlowska E, Sobczuk P, Chojnacki C, Blasiak J · Nutrients · 2023-12-02

Other

29. The Effect of Three Different Ketogenic Diet Protocols on Migraine and Fatigue in Chronic and High-Frequency Episodic Migraine: A Pilot Study.

Tereshko Y, Dal Bello S, Di Lorenzo C, Pittino A, Filippi F, Belgrado E, Lettieri C, Merlino G, Gigli GL, Valente M · Nutrients · 2023-10-11

Observational human study

30. 2:1 ketogenic diet and low-glycemic-index diet for the treatment of chronic and episodic migraine: a single-center real-life retrospective study.

Tereshko Y, Dal Bello S, Di Lorenzo C, Pez S, Pittino A, Sartor R, Filippi F, Lettieri C, Belgrado E, Garbo R, Merlino G, Gigli GL, Valente M · The journal of headache and pain · 2023-07-28

Other

31. Sleep of migraine patients is ameliorated by ketogenic diet, independently of pain control.

Merlino G, Tereshko Y, Pez S, Dal Bello S, Pittino A, Di Lorenzo C, Filippi F, Lettieri C, Belgrado E, Gigli GL, Valente M · Sleep medicine · 2023-05-09

Randomized clinical trial

32. Metabolic markers of short and long-term exogenous DL-beta-hydroxybutyrate supplementation in episodic migraine patients: an exploratory analysis of a randomized-controlled-trial.

Putananickal N, Gross EC, Orsini AL, Schmidt S, Hafner P, Gocheva V, Nagy S, Henzi BC, Rubino D, Schädelin S, Sandor P, Fischer D · Frontiers in pharmacology · 2023-05-04

Randomized clinical trial

33. Ketogenic diet in refractory migraine: possible efficacy and role of ketone bodies-a pilot experience.

Lovati C, d'Alessandro CM, Ventura SD, Muzio F, Pantoni L · Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2022-08-11

Clinical trial / intervention

34. Migraine Prevention through Ketogenic Diet: More than Body Mass Composition Changes.

Valente M, Garbo R, Filippi F, Antonutti A, Ceccarini V, Tereshko Y, Di Lorenzo C, Gigli GL · Journal of clinical medicine · 2022-08-23

Systematic review / meta-analysis

35. Efficacy and tolerability of the ketogenic diet and its variations for preventing migraine in adolescents and adults: a systematic review.

Caminha MC, Moreira AB, Matheus FC, Rieger DK, Moreira JD, Dalmarco EM, Demarchi IG, Lin K · Nutrition reviews · 2021-10-20

Randomized clinical trial

36. Efficacy and safety of exogenous beta-hydroxybutyrate for preventive treatment in episodic migraine: A single-centred, randomised, placebo-controlled, double-blind crossover trial.

Putananickal N, Gross EC, Orsini AL, Schmidt S, Hafner P, Gocheva V, Nagy S, Henzi BC, Rubino D, Vogt DR, Cichon S, Sandor P, Fischer D · Cephalalgia : an international journal of headache · 2021-09-20

Other

37. Effectiveness of ketogenic diet in treatment of patients with refractory chronic migraine.

Bongiovanni D, Benedetto C, Corvisieri S, Del Favero C, Orlandi F, Allais G, Sinigaglia S, Fadda M · Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2021-02-01

Randomized clinical trial

38. Can Ketogenic Diet Therapy Improve Migraine Frequency, Severity and Duration?

Haslam RL, Bezzina A, Herbert J, Spratt N, Rollo ME, Collins CE · Healthcare (Basel, Switzerland) · 2021-08-26

Review

39. Hemiplegic Migraine in Glut1 Deficiency Syndrome and Paroxysmal Dyskinesia at Ketogenic Diet Induction: Case Report and Literature Review.

Gburek-Augustat J, Heinze A, Abou Jamra R, Merkenschlager A · Movement disorders clinical practice · 2020-10-06

Observational human study

40. A ketogenic diet normalizes interictal cortical but not subcortical responsivity in migraineurs.

Di Lorenzo C, Coppola G, Bracaglia M, Di Lenola D, Sirianni G, Rossi P, Di Lorenzo G, Parisi V, Serrao M, Cervenka MC, Pierelli F · BMC neurology · 2019-06-22

Clinical trial / intervention

41. Potential Protective Mechanisms of Ketone Bodies in Migraine Prevention.

Gross EC, Klement RJ, Schoenen J, D'Agostino DP, Fischer D · Nutrients · 2019-04-10

Randomized clinical trial

42. Efficacy and safety of exogenous ketone bodies for preventive treatment of migraine: A study protocol for a single-centred, randomised, placebo-controlled, double-blind crossover trial.

Gross E, Putananickal N, Orsini AL, Schmidt S, Vogt DR, Cichon S, Sandor P, Fischer D · Trials · 2019-01-17

Randomized clinical trial

43. Ketogenic diet in migraine: rationale, findings and perspectives.

Barbanti P, Fofi L, Aurilia C, Egeo G, Caprio M · Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2017-05-21

Other

44. Cortical functional correlates of responsiveness to short-lasting preventive intervention with ketogenic diet in migraine: a multimodal evoked potentials study.

Di Lorenzo C, Coppola G, Bracaglia M, Di Lenola D, Evangelista M, Sirianni G, Rossi P, Di Lorenzo G, Serrao M, Parisi V, Pierelli F · The journal of headache and pain · 2016-05-31

Other

45. O017. Cortical functional correlates of responsiveness to short-lasting preventive intervention with ketogenic diet (KD) in migraine: a multimodal evoked potentials study.

Bracaglia M, Coppola G, Di Lorenzo C, Di Lenola D, Pierelli F · The journal of headache and pain · 2017-01-30

Other

46. O045. Cluster headache improvement during Ketogenic Diet.

Di Lorenzo C, Coppola G, Sirianni G, Rossi P, Pierelli F · The journal of headache and pain · 2017-01-30

Other

47. Ketogenic diet in migraine treatment: a brief but ancient history.

Maggioni F, Margoni M, Zanchin G · Cephalalgia : an international journal of headache · 2011-07-04

Clinical trial / intervention

48. Use of the modified Atkins diet for adolescents with chronic daily headache.

Kossoff EH, Huffman J, Turner Z, Gladstein J · Cephalalgia : an international journal of headache · 2010-03-26

Multiple Sclerosis Recent peer-reviewed literature

Only papers directly addressing multiple sclerosis or ketogenic/ketone mechanisms with clear MS relevance are retained.

Recent human study · 2026

1. Ketogenic Diet-Based Therapy for Fatigue in Patients with Multiple Sclerosis

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Disease-focused review

2. The impact of ketogenic diet on the onset and progression of multiple sclerosis

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Preclinical mechanistic study

3. Effect of β-hydroxybutyrate on behavioral alterations, molecular and morphological changes in CNS of multiple sclerosis mouse model

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Review including multiple sclerosis

4. Impact of the Ketogenic Diet on Neurological Diseases

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Recent neurological review · 2025

5. Exploring the Neurological Impacts of the Ketogenic Diet

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Mechanistic review

6. Molecular Mechanisms of Neuroprotection by Ketone Bodies and Ketogenic Diet in Cerebral Ischemia and Neurodegenerative Diseases

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Neurological review

7. The Role of Ketogenic Diet in the Treatment of Neurological Diseases

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Mechanistic review

8. Effects of Ketogenic Diet on Neuroinflammation in Neurodegenerative Diseases

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Review · 2025

9. The Role of Nutrition and Physical Activity in Multiple Sclerosis

Original publication title: The Role of Nutrition and Physical Activity in Multiple Sclerosis

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Review / comparative evidence · 2023

10. Effectiveness of Various Diet Patterns among Patients with Multiple Sclerosis

Original publication title: Effectiveness of Various Diet Patterns among Patients with Multiple Sclerosis

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Preclinical mechanistic study

11. Effect of β-Hydroxybutyrate on Behavioral Alterations, Molecular and Morphological Changes in the CNS of a Multiple Sclerosis Mouse Model

Original publication title: Effect of β-Hydroxybutyrate on Behavioral Alterations, Molecular and Morphological Changes in the CNS of a Multiple Sclerosis Mouse Model

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Review

12. The Role of Diet and Gut Microbiome in Multiple Sclerosis

Original publication title: The Role of Diet and Gut Microbiome in Multiple Sclerosis

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Clinical / review evidence

13. Therapeutic Alternative of the Ketogenic Mediterranean Diet in Multiple Sclerosis

Original publication title: Therapeutic Alternative of the Ketogenic Mediterranean Diet in Multiple Sclerosis

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Randomized clinical trial

14. Ketogenic Diet-Based Therapy for Fatigue in Patients with Multiple Sclerosis.

Filippi F, Lorenzut S, Garbo R, Lamon E, Del Negro I, Nilo A, Pez S, Gigli GL, Valente M · Nutrients · 2026-05-08

Preclinical / mechanistic

15. A KETOGENIC DIET PROMOTES BLOOD-SPINAL CORD BARRIER RESEALING TO DECREASE SPINAL CORD IMMUNE CELL INFILTRATION IN A PRECLINICAL MODEL OF MULTIPLE SCLEROSIS.

Plafker KS, Walton DA, Pezant N, Plafker SM · bioRxiv : the preprint server for biology · 2026-03-24

Preclinical / mechanistic

16. A2 astrocyte polarization mediates ketogenic diet protection of blood-central nervous system barriers in experimental autoimmune encephalomyelitis.

Zhang Q, Zheng M, Siebert HC, Wang Q, Zhang R, Zhang N · Neural regeneration research · 2025-12-30

Clinical trial / intervention

17. Impact of a ketogenic diet on sleep quality in people with relapsing multiple sclerosis.

Perlman J, Wetmore E, Lehner-Gulotta D, Banwell B, Bergqvist AGC, Coleman R, Chen S, Conaway M, Goldman MD, Morse AM, Brenton JN · Sleep medicine · 2024-08-28

Other

18. Ketogenic diet may improve sleep quality and daytime somnolence in patients affected by multiple sclerosis. Results of an exploratory study.

Merlino G, Garbo R, Dal Bello S, Del Negro I, Lamon E, Filippi F, Bernardini A, Lorenzut S, Ceccarelli L, Cella A, Marè A, Tereshko Y, Gigli GL, Valente M · Sleep medicine · 2023-10-20

Clinical trial / intervention

19. Ketogenic diet in relapsing multiple sclerosis: Patient perceptions, post-trial diet adherence & outcomes.

Wetmore E, Lehner-Gulotta D, Florenzo B, Banwell B, Bergqvist AGC, Coleman R, Conaway M, Goldman MD, Brenton JN · Clinical nutrition (Edinburgh, Scotland) · 2023-07-04

Clinical trial / intervention

20. Serum neurofilament light chain in relapsing multiple sclerosis patients on a ketogenic diet.

Oh U, Woolbright E, Lehner-Gulotta D, Coleman R, Conaway M, Goldman MD, Brenton JN · Multiple sclerosis and related disorders · 2023-03-25

Review

21. Ketogenic and Modified Mediterranean Diet as a Tool to Counteract Neuroinflammation in Multiple Sclerosis: Nutritional Suggestions.

Di Majo D, Cacciabaudo F, Accardi G, Gambino G, Giglia G, Ferraro G, Candore G, Sardo P · Nutrients · 2022-06-08

Randomized clinical trial

22. A Modified MCT-Based Ketogenic Diet Increases Plasma β-Hydroxybutyrate but Has Less Effect on Fatigue and Quality of Life in People with Multiple Sclerosis Compared to a Modified Paleolithic Diet: A Waitlist-Controlled, Randomized Pilot Study.

Lee JE, Titcomb TJ, Bisht B, Rubenstein LM, Louison R, Wahls TL · Journal of the American College of Nutrition · 2020-03-26

Preclinical / mechanistic

23. Cuprizone-Induced Demyelination in Mouse Hippocampus Is Alleviated by Ketogenic Diet.

Liu C, Zhang N, Zhang R, Jin L, Petridis AK, Loers G, Zheng X, Wang Z, Siebert HC · Journal of agricultural and food chemistry · 2020-09-23

Randomized clinical trial

24. Ketogenic diet and fasting diet as Nutritional Approaches in Multiple Sclerosis (NAMS): protocol of a randomized controlled study.

Bahr LS, Bock M, Liebscher D, Bellmann-Strobl J, Franz L, Prüß A, Schumann D, Piper SK, Kessler CS, Steckhan N, Michalsen A, Paul F, Mähler A · Trials · 2020-01-02

Other

25. Reply to "When Is a Ketogenic Diet Ketogenic? Comment on Satiating Effect of a Ketogenic Diet and Its Impact on Muscle Improvement and Oxidation State in Multiple Sclerosis Patients. Nutrients 2019, 11, 1156".

Benlloch M, López-Rodríguez MM, Cuerda-Ballester M, Drehmer E, Carrera S, Ceron JJ, Tvarijonaviciute A, Chirivella J, Fernández-García D, de la Rubia Ortí JE · Nutrients · 2019-08-15

Other

26. When is a Ketogenic Diet Ketogenic? Comment on "Satiating Effect of a Ketogenic Diet and Its Impact on Muscle Improvement and Oxidation State in Multiple Sclerosis Patients, Nutrients 2019, 11, 1156".

Klement RJ · Nutrients · 2019-08-15

Other

27. Pilot study of a ketogenic diet in relapsing-remitting MS.

Brenton JN, Banwell B, Bergqvist AGC, Lehner-Gulotta D, Gampper L, Leytham E, Coleman R, Goldman MD · Neurology(R) neuroimmunology & neuroinflammation · 2019-04-12

Clinical trial / intervention

28. Satiating Effect of a Ketogenic Diet and Its Impact on Muscle Improvement and Oxidation State in Multiple Sclerosis Patients.

Benlloch M, López-Rodríguez MM, Cuerda-Ballester M, Drehmer E, Carrera S, Ceron JJ, Tvarijonaviciute A, Chirivella J, Fernández-García D, de la Rubia Ortí JE · Nutrients · 2019-05-23

Randomized clinical trial

29. Ketogenic diets attenuate cyclooxygenase and lipoxygenase gene expression in multiple sclerosis.

Bock M, Karber M, Kuhn H · EBioMedicine · 2018-10-03

Other

30. Reduced Mass and Diversity of the Colonic Microbiome in Patients with Multiple Sclerosis and Their Improvement with Ketogenic Diet.

Swidsinski A, Dörffel Y, Loening-Baucke V, Gille C, Göktas Ö, Reißhauer A, Neuhaus J, Weylandt KH, Guschin A, Bock M · Frontiers in microbiology · 2017-06-28

Review

31. The Therapeutic Potential of the Ketogenic Diet in Treating Progressive Multiple Sclerosis.

Storoni M, Plant GT · Multiple sclerosis international · 2015-12-29

Preclinical / mechanistic

32. Inflammation-mediated memory dysfunction and effects of a ketogenic diet in a murine model of multiple sclerosis.

Kim DY, Hao J, Liu R, Turner G, Shi FD, Rho JM · PloS one · 2012-05-02

Review

33. Exploring the Ketogenic Diet as Adjunctive Therapy in Multiple Sclerosis: A Review.

Rasheed S, Uzair M, Anas M, Batool Naqvi SS, Aijaz U, Raza AA, Samadi A · Restorative neurology and neuroscience · 2025-12-10

Systematic review / meta-analysis

34. The role and benefits of ketogenic diet in modulating inflammation in multiple sclerosis: A systematic review and meta-analysis.

Reddy NJ, Benjamin NZY, Reddy PH, Thai A, Rawashdeh HMA, Saravanan C, Prajjwal P, Tekuru Y, Inban P, John J · Disease-a-month : DM · 2025-10-09

Other

35. Foreword: Role of Bruton tyrosine kinase inhibitors and ketogenic diet for inflammatory modulation in multiple sclerosis.

Disease-a-month : DM · 2025-09-09

Randomized clinical trial

36. Fasting, ketogenic, and anti-inflammatory diets in multiple sclerosis: a randomized controlled trial with 18-month follow-up.

Bahr LS, Bellmann-Strobl J, Koppold DA, Rust R, Schmitz-Hübsch T, Olszewska M, Stadlbauer J, Bock M, Scheel M, Chien C, Multmeier J, Krannich A, Michalsen A, Paul F, Mähler A · BMC nutrition · 2025-08-20

Systematic review / meta-analysis

37. Safety and Efficacy of Ketogenic Diet in the Management of Multiple Sclerosis: A Systematic Review.

Kakde SP, Qadeer A, Khalil M, Dhami A, Rashid Z, Zahir D, Ahsan SA, Dhillon TA, Siddique MU, Uzokwe MC · Cureus · 2025-08-13

Preclinical / mechanistic

38. A high-saturated, long-chain fatty acid ketogenic diet negatively impacts visual and motor-sensory function in a pre-clinical model of multiple sclerosis.

Capper EN, Anders JJ, Elwood BW, Kardon RH, Gramlich OW · Frontiers in immunology · 2025-05-22

Psychiatry & Behaviour

Autism Spectrum Disorder Recent peer-reviewed literature

Source-audited references from the connected PDF archive. Only papers directly relevant to this topic and ketogenic therapy/ketosis are shown.

1. Effects of a ketogenic diet on PTEN mutation-associated autism spectrum disorder

Bibliographic record reviewed for inclusion in the curated Scientific Library.

2. Vocal communication in asocial BTBR mice is more malleable by a ketogenic diet

Bibliographic record reviewed for inclusion in the curated Scientific Library.

3. Dietary and Metabolic Approaches for Treating Autism Spectrum Disorders, Affective Disorders and Cognitive Impairment Comorbid with Epilepsy

Bibliographic record reviewed for inclusion in the curated Scientific Library.

4. Potential Therapeutic Use of the Ketogenic Diet in Autism Spectrum Disorder

Bibliographic record reviewed for inclusion in the curated Scientific Library.

5. Ketogenic Diet: A Dietary Intervention via Gut Microbiota in Autism Spectrum Disorder

Bibliographic record reviewed for inclusion in the curated Scientific Library.

6. Ketogenic and Low FODMAP Diet in Therapeutic Management of a Young Autistic Patient with Epilepsy and Dysmetabolism

Bibliographic record reviewed for inclusion in the curated Scientific Library.

7. Ketogenic Dietary Therapies in Patients with Autism Spectrum Disorder

Bibliographic record reviewed for inclusion in the curated Scientific Library.

8. Efficacy and Safety of Diet Therapies in Autism Spectrum Disorder including ketogenic interventions

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Scoping review · 2025

9. Nutritional Approaches in Autism Spectrum Disorder: A Scoping Review

Original publication title: Nutritional Approaches in Autism Spectrum Disorder: A Scoping Review

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Preclinical autism model

10. Vocal Communication in Asocial BTBR Mice Is Modulated by a Ketogenic Diet

Original publication title: Vocal Communication in Asocial BTBR Mice Is Modulated by a Ketogenic Diet

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Case report

11. Ketogenic and Low-FODMAP Diet in the Therapeutic Management of a Young Autistic Patient with Epilepsy and Dysmetabolism

Original publication title: Ketogenic and Low-FODMAP Diet in the Therapeutic Management of a Young Autistic Patient with Epilepsy and Dysmetabolism

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Randomized clinical trial

12. Comparison of clinical efficacy and gut microbiota characteristics in children with ASD treated with fecal microbiota transplantation and ketogenic diet.

Wang Y, Wang L, Cai Z, Yu L, Guo Y, Zhang L, Zhu M, Liu Z, Zhao Y, Liu L, Cao A · BMC psychiatry · 2026-09-02

Preclinical / mechanistic

13. Ketogenic diet improves motor and anxiety-like behaviors plus cerebellar inflammation via axonal remyelination in the BTBR mouse model of autism.

Alò R, Olivito I, Minervini D, Avolio E, De Bartolo A, Perrotta I, Cerra MC, Angelone T, Rocca C, Facciolo RM · The Journal of nutritional biochemistry · 2026-05-15

Randomized clinical trial

14. Plasma metabolomic signatures in children with autism spectrum disorder and their modulation following a gluten-free modified ketogenic diet.

Singh R, Shah A, Jain N, Shah H, Rawal R · BMC psychiatry · 2026-03-16

Review

15. Ketogenic diet as a therapeutic approach in autism spectrum disorder: a narrative review.

Öztürk E, Aslan Çin NN, Cansu A, Akyol A · Metabolic brain disease · 2024-12-18

Clinical trial / intervention

16. Vocal communication in asocial BTBR mice is more malleable by a ketogenic diet in juveniles than adults.

Möhrle D, Murari K, Rho JM, Cheng N · Neuroscience · 2024-10-15

Clinical trial / intervention

17. Ketogenic Diet Induced Shifts in the Gut Microbiome Associate with Changes to Inflammatory Cytokines and Brain-Related miRNAs in Children with Autism Spectrum Disorder.

Allan NP, Yamamoto BY, Kunihiro BP, Nunokawa CKL, Rubas NC, Wells RK, Umeda L, Phankitnirundorn K, Torres A, Peres R, Takahashi E, Maunakea AK · Nutrients · 2024-05-07

Preclinical / mechanistic

18. Ketogenic diet ameliorates autism spectrum disorders-like behaviors via reduced inflammatory factors and microbiota remodeling in BTBR T+ Itpr3tf/J mice.

Olivito I, Avolio E, Minervini D, Soda T, Rocca C, Angelone T, Iaquinta FS, Bellizzi D, De Rango F, Bruno R, De Bartolo L, Alò R, Canonaco M, Facciolo RM · Experimental neurology · 2023-05-05

Clinical trial / intervention

19. Assessing the feasibility of using the ketogenic diet in autism spectrum disorder.

Albers J, Kraja G, Eller D, Eck K, McBrian D, Bain JM · Journal of human nutrition and dietetics : the official journal of the British Dietetic Association · 2023-01-22

Preclinical / mechanistic

20. Rescue of histone hypoacetylation and social deficits by ketogenic diet in a Shank3 mouse model of autism.

Qin L, Ma K, Yan Z · Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2021-10-26

Case report / case series

21. Florid Scurvy in an Autistic Child on a Ketogenic Diet.

Ahmad SA, Al Thobiti TA, El Toum M, Al Harbi F · Pediatric emergency care · 2018-11-22

Clinical trial / intervention

22. Ketogenic Dietary Therapies in Patients with Autism Spectrum Disorder: Facts or Fads? A Scoping Review and a Proposal for a Shared Protocol.

Varesio C, Grumi S, Zanaboni MP, Mensi MM, Chiappedi M, Pasca L, Ferraris C, Tagliabue A, Borgatti R, De Giorgis V · Nutrients · 2021-06-16

Review

23. A Ketogenic Diet and the Treatment of Autism Spectrum Disorder.

Li Q, Liang J, Fu N, Han Y, Qin J · Frontiers in pediatrics · 2021-05-11

Preclinical / mechanistic

24. Gestational exposure to a ketogenic diet increases sociability in CD-1 mice.

Arqoub AMS, Flynn KG, Martinez LA · Behavioral neuroscience · 2020-03-30

Clinical trial / intervention

25. Metabolic Framework for the Improvement of Autism Spectrum Disorders by a Modified Ketogenic Diet: A Pilot Study.

Mu C, Corley MJ, Lee RWY, Wong M, Pang A, Arakaki G, Miyamoto R, Rho JM, Mickiewicz B, Dowlatabadi R, Vogel HJ, Korchemagin Y, Shearer J · Journal of proteome research · 2019-11-22

Clinical trial / intervention

26. A modified ketogenic gluten-free diet with MCT improves behavior in children with autism spectrum disorder.

Lee RWY, Corley MJ, Pang A, Arakaki G, Abbott L, Nishimoto M, Miyamoto R, Lee E, Yamamoto S, Maunakea AK, Lum-Jones A, Wong M · Physiology & behavior · 2018-02-05

Randomized clinical trial

27. Ketogenic diet versus gluten free casein free diet in autistic children: a case-control study.

El-Rashidy O, El-Baz F, El-Gendy Y, Khalaf R, Reda D, Saad K · Metabolic brain disease · 2017-08-14

Preclinical / mechanistic

28. Ketogenic diet leads to O-GlcNAc modification in the BTBRT+tf/j mouse model of autism.

Newell C, Johnsen VL, Yee NC, Xu WJ, Klein MS, Khan A, Rho JM, Shearer J · Biochimica et biophysica acta. Molecular basis of disease · 2017-05-11

Preclinical / mechanistic

29. The effect of ketogenic diet in an animal model of autism induced by prenatal exposure to valproic acid.

Castro K, Baronio D, Perry IS, Riesgo RDS, Gottfried C · Nutritional neuroscience · 2016-02-08

Preclinical / mechanistic

30. Genetic modifications associated with ketogenic diet treatment in the BTBRT+Tf/J mouse model of autism spectrum disorder.

Mychasiuk R, Rho JM · Autism research : official journal of the International Society for Autism Research · 2016-08-16

Preclinical / mechanistic

31. Ketogenic diet improves behaviors in a maternal immune activation model of autism spectrum disorder.

Ruskin DN, Murphy MI, Slade SL, Masino SA · PloS one · 2017-02-06

Preclinical / mechanistic

32. Ketogenic diets improve behaviors associated with autism spectrum disorder in a sex-specific manner in the EL mouse.

Ruskin DN, Fortin JA, Bisnauth SN, Masino SA · Physiology & behavior · 2016-11-09

Preclinical / mechanistic

33. Ketogenic diet modifies the gut microbiota in a murine model of autism spectrum disorder.

Newell C, Bomhof MR, Reimer RA, Hittel DS, Rho JM, Shearer J · Molecular autism · 2016-09-01

Clinical trial / intervention

34. Ketogenic diet exposure during the juvenile period increases social behaviors and forebrain neural activation in adult Engrailed 2 null mice.

Verpeut JL, DiCicco-Bloom E, Bello NT · Physiology & behavior · 2016-04-11

Randomized clinical trial

35. [Autism spectrum disorder and epilepsy: the role of ketogenic diet].

Garcia-Penas JJ · Revista de neurologia · 2016-03-01

Preclinical / mechanistic

36. The ketogenic diet modifies social and metabolic alterations identified in the prenatal valproic acid model of autism spectrum disorder.

Ahn Y, Narous M, Tobias R, Rho JM, Mychasiuk R · Developmental neuroscience · 2014-07-08

Preclinical / mechanistic

37. Ketogenic diet improves core symptoms of autism in BTBR mice.

Ruskin DN, Svedova J, Cote JL, Sandau U, Rho JM, Kawamura M, Boison D, Masino SA · PloS one · 2013-06-05

Clinical trial / intervention

38. Application of a ketogenic diet in children with autistic behavior: pilot study.

Evangeliou A, Vlachonikolis I, Mihailidou H, Spilioti M, Skarpalezou A, Makaronas N, Prokopiou A, Christodoulou P, Liapi-Adamidou G, Helidonis E, Sbyrakis S, Smeitink J · Journal of child neurology · 2003-04-16

Clinical trial / intervention

39. Exploring the potential of the ketogenic diet in autism spectrum disorder: metabolic, genetic, and therapeutic insights.

Schrickel A, Groeneweg J, Dekeyster E · Metabolic brain disease · 2025-01-08

Psychiatry & Mental Health Recent peer-reviewed literature

Source-audited references from the connected PDF archive. Only papers directly relevant to this topic and ketogenic therapy/ketosis are shown.

1. Effect of 3 months of ketogenic diet on euthymia in bipolar II disorder

Bibliographic record reviewed for inclusion in the curated Scientific Library.

2. Cognitive behavioral therapy for bipolar disorder: patient-level participation barriers and ketogenic metabolic therapy as a candidate adjunct

Bibliographic record reviewed for inclusion in the curated Scientific Library.

3. The Role of the Ketogenic Diet in Modulating Biochemical Pathophysiology in Psychiatric and Neurodegenerative Disorders

Bibliographic record reviewed for inclusion in the curated Scientific Library.

4. Ketogenic diet-derived faecal microbiota and schizophrenia

Bibliographic record reviewed for inclusion in the curated Scientific Library.

5. The Ketogenic Diet: An Anti-Inflammatory Approach for Schizophrenia

Bibliographic record reviewed for inclusion in the curated Scientific Library.

6. Clinical Insights Into the Mechanistic Crossroads of Lamotrigine and Therapeutic Ketosis in Bipolar Depression

Bibliographic record reviewed for inclusion in the curated Scientific Library.

7. Effects of a ketogenic diet on bipolar disorder

Bibliographic record reviewed for inclusion in the curated Scientific Library.

8. Ketogenic diet as a therapeutic intervention for obsessive-compulsive disorder: a case series of three patients

Bibliographic record reviewed for inclusion in the curated Scientific Library.

9. Perspectives on the Ketogenic Diet as a Non-pharmacological Intervention in Mental Health

Bibliographic record reviewed for inclusion in the curated Scientific Library.

10. Ketogenic metabolic therapy in the remission of chronic major depressive disorder

Bibliographic record reviewed for inclusion in the curated Scientific Library.

11. A pilot study of a ketogenic diet in bipolar disorder: clinical, metabolic and magnetic resonance spectroscopy findings

Bibliographic record reviewed for inclusion in the curated Scientific Library.

12. Pilot study of a ketogenic diet in bipolar disorder: a process evaluation

Bibliographic record reviewed for inclusion in the curated Scientific Library.

13. KETO-MOOD: Ketogenic Diet for Microbiome Optimization in Mood Disorders

Bibliographic record reviewed for inclusion in the curated Scientific Library.

14. Ketogenic diets in clinical psychology

Bibliographic record reviewed for inclusion in the curated Scientific Library.

15. Ketogenic metabolic therapy in the effective management of treatment-resistant depressive symptoms in bipolar disorder

Bibliographic record reviewed for inclusion in the curated Scientific Library.

16. The Potential Effects of the Ketogenic Diet in the Prevention and Co-Treatment of Stress, Anxiety, Depression, Schizophrenia, and Bipolar Disorder

Bibliographic record reviewed for inclusion in the curated Scientific Library.

17. Complete remission of depression and anxiety using a ketogenic diet: case series

Bibliographic record reviewed for inclusion in the curated Scientific Library.

18. Ketogenic diet has a positive association with mental and emotional health

Bibliographic record reviewed for inclusion in the curated Scientific Library.

19. Evaluating the efficacy and mechanisms of a ketogenic diet as adjunctive treatment in serious mental illness

Bibliographic record reviewed for inclusion in the curated Scientific Library.

20. Ketogenic Diet Intervention on Metabolic and Psychiatric Health in Bipolar Disorder and Schizophrenia

Bibliographic record reviewed for inclusion in the curated Scientific Library.

21. Sleep, mood disorders, and the ketogenic diet: potential therapeutic targets for bipolar disorder and schizophrenia

Bibliographic record reviewed for inclusion in the curated Scientific Library.

22. Ketogenic-Mimicking Diet as a Therapeutic Modality for Bipolar Disorder: Biomechanistic Rationale and Protocol for a Pilot Clinical Trial

Bibliographic record reviewed for inclusion in the curated Scientific Library.

23. Pilot study of a ketogenic diet in bipolar disorder

Bibliographic record reviewed for inclusion in the curated Scientific Library.

24. Exploring the role of ketone bodies in the diagnosis and treatment of psychiatric disorders

Bibliographic record reviewed for inclusion in the curated Scientific Library.

25. Ketogenic diet in therapy of bipolar affective disorder

Bibliographic record reviewed for inclusion in the curated Scientific Library.

26. Ketogenic diet for mood disorders: from animal models to clinical application

Bibliographic record reviewed for inclusion in the curated Scientific Library.

27. The Role of Ketogenic Metabolic Therapy on the Brain in Serious Mental Illness

Bibliographic record reviewed for inclusion in the curated Scientific Library.

28. Ketosis and bipolar disorder

Bibliographic record reviewed for inclusion in the curated Scientific Library.

29. The Ketogenic Diet for Refractory Mental Illness

Bibliographic record reviewed for inclusion in the curated Scientific Library.

30. Ketogenic diet as a metabolic treatment for mental illness

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Randomized clinical trial

31. A randomized controlled trial of a multimodality digital health intervention to aid the delivery of the modified ketogenic diet therapy for epilepsy: The Keto eCoach trial protocol.

Kaul N, Vivash L, Chen S, King L, Johns H, Churilov L, Chen Z, Nicolo JP, Heaven D, Meredith E, Ervine R, Todd L, Zappa B, Ademi Z, Geethadevi GM, Erlichster M, Skafidas E, O'Brien TJ, Kwan P · Epilepsia open · 2026-09-07

Clinical trial / intervention

32. From diet to drinking behavior: Ketogenic diet decreases ethanol intake in young adult female mice.

Torres-Rubio L, Mellado S, Montagud-Romero S, Pascual M, Rodríguez-Arias M · Behavioural brain research · 2026-09-05

Preclinical / mechanistic

33. Ketamine enhances ketogenic diet-induced resilience to activity-based anorexia of adult mice through hippocampal synaptic plasticity.

Wang J, Ge O, Dong Y, Lee E, Aoki C · Neuroscience · 2026-09-01

Clinical trial / intervention

34. Participant food tracking in psychiatric ketogenic metabolic therapy: an unresolved clinical, psychosocial, and implementation question.

Laurent N · Frontiers in nutrition · 2026-08-06

Observational human study

35. Ketogenic diet for pediatric drug-resistant epilepsy: sleep, children's psychosocial functioning, and maternal mental health.

Nassar MF, El-Rashidy OF, Shata MO, ElHagaar MA, Abdelmageed RI · Pediatric research · 2026-07-28

Clinical trial / intervention

36. [Impact of a 3-Month Ketogenic Diet on Euthymia in Bipolar II Disorder: A Case Report].

Rioux C, Cholette-Tétrault S, Dumas V, Cunnane S, Zemmour K · Sante mentale au Quebec · 2026-07-23

Clinical trial / intervention

37. A 6-week ketogenic diet in treatment-resistant depression: a prospective single-arm feasibility pilot trial.

Cukaci C, Rabl U, Frey R · Frontiers in nutrition · 2026-07-22

Clinical trial / intervention

38. Hypomanic symptoms and first manic episode during ketogenic diet treatment in a patient taking venlafaxine: a case report with longitudinal glucose-ketone index and clinical monitoring.

Pou-Álvarez M, Casanovas F, Córcoles D, León-Caballero J, Sabaté A, González-Fresnedo AM, Samos P, Perez-Sola V, Martín LM · Frontiers in nutrition · 2026-07-16

Guideline / consensus

39. International advocacy for ketogenic diet research in schizophrenia: insights from a public petition.

Murray SL, Roche DJO, Palmer CM, Chen S, Lee H, Vyas G, Adams HA, Harrington V, Kelly DL · Frontiers in public health · 2026-07-14

Observational human study

40. Modified Atkins diet therapy in adult drug-resistant epilepsy: Quality of life and mental health outcomes.

Carneiro RAVD, Cardoso RM, Lunardi MDS, Lima MC, Anzani S, Darella AX, Salvador MT, de Paula Moraes T, Sostizzo NC, Venske DK, Moreira JD, Ribeiro LC, Borgatto AF, Lin K · Epilepsia · 2026-07-09

Preclinical / mechanistic

41. Influence of Ketogenic Diet Lipid Composition on Anxiety-Like Behavior and Neurometabolic Profile in Healthy Rats.

Gurgel GG, de Souza JG, Braga RAM, Rodrigues FM, Faccioli AM, Fortes MEG, da Silva EA, Freitas RAMS, Arida RM, Scorza CA, Bernardes ES, Dos Santos SN, Damasceno NRT · Molecular neurobiology · 2026-06-25

Observational human study

42. Cognitive behavioral therapy for bipolar disorder: patient-level participation barriers and ketogenic metabolic therapy as a candidate adjunct.

Laurent N · Frontiers in psychology · 2026-06-15

Clinical trial / intervention

43. Symptom impact and safety of ketogenic therapy in adults with anorexia nervosa: a feasibility trial.

Frank GKW, Scolnick B, Beckwith C, Shott ME, Kilty S, Swindle S, Lutter M, Rho JM · Communications medicine · 2026-06-03

Review

44. The Role of the Ketogenic Diet in Modulating Biochemical Pathophysiology in Psychiatric and Neurodegenerative Disorders.

Chang YB, Baleja JD · International journal of molecular sciences · 2026-05-29

Preclinical / mechanistic

45. Ketogenic diet improves motor and anxiety-like behaviors plus cerebellar inflammation via axonal remyelination in the BTBR mouse model of autism.

Alò R, Olivito I, Minervini D, Avolio E, De Bartolo A, Perrotta I, Cerra MC, Angelone T, Rocca C, Facciolo RM · The Journal of nutritional biochemistry · 2026-05-15

Preclinical / mechanistic

46. Ketogenic Diet Modulates Depressive-Like Behavior via Gut Bacterial Metabolism of Tyrosine.

Zhang Y, Li X, Zhang X, Wang Y, Chen Z, Lin X, Zheng X, Hao H, Zhang X · FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026-05-14

Randomized clinical trial

47. Ketogenic Diet-Based Therapy for Fatigue in Patients with Multiple Sclerosis.

Filippi F, Lorenzut S, Garbo R, Lamon E, Del Negro I, Nilo A, Pez S, Gigli GL, Valente M · Nutrients · 2026-05-08

Other

48. A Closer Look at Ketogenic Diet Effects in Depression.

Richardson K, Rocks T, O'Neil A · JAMA psychiatry · 2026-05-06

Preclinical / mechanistic

49. Ketogenic diet-derived faecal microbiota transplantation improved sensorimotor gating deficits in an acute NMDA-receptor antagonist model of schizophrenia in mice.

Kraeuter AK, Sarnyai Z · Food & function · 2026-04-27

Clinical trial / intervention

50. Emergence of hypomania and mania following initiation of a ketogenic diet: case series.

Palmer CM · Frontiers in nutrition · 2026-04-08

Randomized clinical trial

51. A Ketogenic Diet for Treatment-Resistant Depression: A Randomized Clinical Trial.

Gao M, Kirk M, Knight H, Lash E, Michalopoulou M, Guess N, Stevens R, Browning M, Weich S, Burnet PWJ, Jebb SA, Aveyard P · JAMA psychiatry · 2026-04-01

Clinical trial / intervention

52. Ketogenic metabolic therapy as a candidate adjunct for CBTp delivery in schizophrenia spectrum disorders.

Laurent N · Frontiers in psychology · 2026-03-25

Clinical trial / intervention

53. Sex-dependent protective effects of a ketogenic diet following prenatal stress exposure: Evidence from adolescent rats.

Begni V, Marchesin A, Orso R, Creutzberg KC, Precetti F, Cattaneo A, Riva MA · Brain, behavior, and immunity · 2026-01-19

Randomized clinical trial

54. Medically supervised ketogenic diet as an adjunctive treatment for moderate to severe depression: A pilot study.

Brietzke E, Fabe J, Bambokian A, Breda V, Chaves C, Shelp J, Terpstra A, Koning E, Groll D, Milev R, McIntyre RS, Mansur RB, Soares CN, Gomes FA · Journal of affective disorders · 2025-12-29

Randomized clinical trial

55. Metabolic Improvements with a Ketogenic Diet Correlate with Symptom Improvement in Psychosis: A Randomized Controlled Trial.

Abram SV, Kyner JM, Vu A, Naeem Z, Sethi S, Jacob MS, Fryer SL, Mathalon DH, Ford JM · Schizophrenia bulletin · 2025-11-25

Clinical trial / intervention

56. Nutritional Strategies in Major Depression Disorder: From Ketogenic Diet to Modulation of the Microbiota-Gut-Brain Axis.

Nikdasti A, Khodadadi ES, Ferdosi F, Dadgostar E, Yahyazadeh S, Heidari P, Ehtiati S, Vakili O, Khatami SH · Molecular neurobiology · 2024-08-28

Clinical trial / intervention

57. Linking Mitochondrial Dysfunction, Neurotransmitter, and Neural Network Abnormalities and Mania: Elucidating Neurobiological Mechanisms of the Therapeutic Effect of the Ketogenic Diet in Bipolar Disorder.

Freyberg Z, Andreazza AC, McClung CA, Phillips ML · Biological psychiatry. Cognitive neuroscience and neuroimaging · 2024-07-23

Review

58. Measuring the effects of ketogenic diet on neuropsychiatric disorder: A scoping review - Letter to the Editor.

Mechlińska A, Włodarczyk A · Progress in neuro-psychopharmacology & biological psychiatry · 2024-12-31

Systematic review / meta-analysis

59. Measuring the effects of ketogenic diet on neuropsychiatric disorder: A scoping review.

Yousufzai W, Singh M, Ahmadi L, Balamurali S, Bavishi D, Ashraf S, Stuart DB, Baronia R, Amor W · Progress in neuro-psychopharmacology & biological psychiatry · 2024-11-26

Randomized clinical trial

60. KETO-MOOD: Ketogenic Diet for Microbiome Optimization and Overcoming Depression - A Protocol for a Randomized Controlled Trial.

Hongler K, Lounici A, Maurer E, Lanz U, Szathmari O, Reuter Y, Nussbaum S, Steinborn I, Haedrich A, Mölling MA, Wein U, Bocek I, Hersberger L, Brühl AB, Lang UE, Liwinski T · Neuroimmunomodulation · 2024-12-19

Other

61. Treatment of Schizophrenia Using Lithium Chloride, a Ketogenic Diet, and Stem Cell Transplantation.

Hedayati A, Masoumi SJ, Zare S, Homayoun M · Iranian journal of medical sciences · 2024-11-01

Case report / case series

62. Case report: Ketogenic diet alleviated anxiety and depression associated with insulin-dependent diabetes management.

Winje E, Lake I, Dankel SN · Frontiers in nutrition · 2024-10-30

Clinical trial / intervention

63. Ketogenic diets in clinical psychology: examining the evidence and implications for practice.

Laurent N, Bellamy EL, Hristova D, Houston A · Frontiers in psychology · 2024-09-26

Randomized clinical trial

64. The effects of ketogenic metabolic therapy on mental health and metabolic outcomes in schizophrenia and bipolar disorder: a randomized controlled clinical trial protocol.

Longhitano C, Finlay S, Peachey I, Swift JL, Fayet-Moore F, Bartle T, Vos G, Rudd D, Shareef O, Gordon S, Azghadi MR, Campbell I, Sethi S, Palmer C, Sarnyai Z · Frontiers in nutrition · 2024-08-21

Observational human study

65. Retrospective case study: ketogenic metabolic therapy in the effective management of treatment-resistant depressive symptoms in bipolar disorder.

Laurent N · Frontiers in nutrition · 2024-08-12

Preclinical / mechanistic

66. Positive and negative schizotypy personality traits are lower in individuals on ketogenic diet in a non-clinical sample.

Garner S, Barkus E, Kraeuter AK · Schizophrenia research · 2024-07-10

Observational human study

67. Ketogenic diet has a positive association with mental and emotional well-being in the general population.

Garner S, Davies E, Barkus E, Kraeuter AK · Nutrition (Burbank, Los Angeles County, Calif.) · 2024-03-09

Clinical trial / intervention

68. Metabolic Insights into Neuropsychiatric Illnesses and Ketogenic Therapies: A Transcriptomic View.

Sahay S, Pulvender P, Rami Reddy MVSR, McCullumsmith RE, O'Donovan SM · International journal of molecular sciences · 2024-07-29

Clinical trial / intervention

69. Understanding the experiences of ketogenic metabolic therapy for people living with varying levels of depressive symptoms: a thematic analysis.

Bellamy EL, Hadjiefthyvoulou F, Walsh J, Brown J, Turner J · Frontiers in nutrition · 2024-06-06

Randomized clinical trial

70. Evaluating the efficacy and mechanisms of a ketogenic diet as adjunctive treatment for people with treatment-resistant depression: A protocol for a randomised controlled trial.

Gao M, Kirk M, Lash E, Knight H, Michalopoulou M, Guess N, Browning M, Weich S, Burnet P, Jebb SA, Stevens R, Aveyard P · Journal of psychiatric research · 2024-04-15

Randomized clinical trial

71. The Potential Effects of the Ketogenic Diet in the Prevention and Co-Treatment of Stress, Anxiety, Depression, Schizophrenia, and Bipolar Disorder: From the Basic Research to the Clinical Practice.

Chrysafi M, Jacovides C, Papadopoulou SK, Psara E, Vorvolakos T, Antonopoulou M, Dakanalis A, Martin M, Voulgaridou G, Pritsa A, Mentzelou M, Giaginis C · Nutrients · 2024-05-21

Clinical trial / intervention

72. The Potential Role of the Ketogenic Diet in Serious Mental Illness: Current Evidence, Safety, and Practical Advice.

Rog J, Wingralek Z, Nowak K, Grudzień M, Grunwald A, Banaszek A, Karakula-Juchnowicz H · Journal of clinical medicine · 2024-05-10

Clinical trial / intervention

73. Ketogenic Diet Intervention on Metabolic and Psychiatric Health in Bipolar and Schizophrenia: A Pilot Trial.

Sethi S, Wakeham D, Ketter T, Hooshmand F, Bjornstad J, Richards B, Westman E, Krauss RM, Saslow L · Psychiatry research · 2024-03-20

Preclinical / mechanistic

74. Sex-specific effects of ketogenic diet on anxiety-like behavior and neuroimmune response in C57Bl/6J mice.

Kumar M, Bhatt B, Gusain C, Mahajan N, Bishnoi M · The Journal of nutritional biochemistry · 2024-02-02

Review

75. Ketogenic diet and behavior: insights from experimental studies.

Grabowska K, Grabowski M, Przybyła M, Pondel N, Barski JJ, Nowacka-Chmielewska M, Liśkiewicz D · Frontiers in nutrition · 2024-02-08

Other

76. From theory to practice: challenges and rewards of implementing ketogenic metabolic therapy in mental health.

Laurent N · Frontiers in nutrition · 2024-02-08

Other

77. Ketogenic diet may improve sleep quality and daytime somnolence in patients affected by multiple sclerosis. Results of an exploratory study.

Merlino G, Garbo R, Dal Bello S, Del Negro I, Lamon E, Filippi F, Bernardini A, Lorenzut S, Ceccarelli L, Cella A, Marè A, Tereshko Y, Gigli GL, Valente M · Sleep medicine · 2023-10-20

Review

78. Exploring the impact of ketogenic diet on multiple sclerosis: obesity, anxiety, depression, and the glutamate system.

Ortí JER, Cuerda-Ballester M, Sanchis-Sanchis CE, Lajara Romance JM, Navarro-Illana E, García Pardo MP · Frontiers in nutrition · 2023-08-25

Randomized clinical trial

79. The Relationship of Ketogenic Diet with Neurodegenerative and Psychiatric Diseases: A Scoping Review from Basic Research to Clinical Practice.

Mentzelou M, Dakanalis A, Vasios GK, Gialeli M, Papadopoulou SK, Giaginis C · Nutrients · 2023-05-11

Systematic review / meta-analysis

80. Efficacy of low carbohydrate and ketogenic diets in treating mood and anxiety disorders: systematic review and implications for clinical practice.

Dietch DM, Kerr-Gaffney J, Hockey M, Marx W, Ruusunen A, Young AH, Berk M, Mondelli V · BJPsych open · 2023-04-17

Review

81. Ketogenic Diet and Inflammation: Implications for Mood and Anxiety Disorders.

El Karkafi R, Gebara T, Salem M, Kamel J, El Khoury G, Zalal M, Fakhoury M · Advances in experimental medicine and biology · 2023-03-23

Case report / case series

82. Ketogenic diet in therapy of bipolar affective disorder - case report and literature review.

Chmiel I · Psychiatria polska · 2022-12-31

Clinical trial / intervention

83. The Ketogenic Diet for Refractory Mental Illness: A Retrospective Analysis of 31 Inpatients.

Danan A, Westman EC, Saslow LR, Ede G · Frontiers in psychiatry · 2022-07-06

Clinical trial / intervention

84. Effects of an low carbohydrate/healthy fat/ketogenic diet on biomarkers of health and symptoms, anxiety and depression in Parkinson's disease: a pilot study.

Tidman MM, White D, White T · Neurodegenerative disease management · 2022-02-18

Clinical trial / intervention

85. Effects of a Ketogenic Diet on Symptoms, Biomarkers, Depression, and Anxiety in Parkinson's Disease: A Case Study.

Tidman M · Cureus · 2022-03-31

Randomized clinical trial

86. Effects of a Low-Carbohydrate Ketogenic Diet on Reported Pain, Blood Biomarkers and Quality of Life in Patients with Chronic Pain: A Pilot Randomized Clinical Trial.

Field R, Pourkazemi F, Rooney K · Pain medicine (Malden, Mass.) · 2021-07-30

Preclinical / mechanistic

87. A combination of ketogenic diet and voluntary exercise ameliorates anxiety and depression-like behaviors in Balb/c mice.

Gumus H, Ilgin R, Koc B, Yuksel O, Kizildag S, Guvendi G, Karakilic A, Kandis S, Hosgorler F, Ates M, Alacam H, Uysal N · Neuroscience letters · 2022-01-03

Review

88. Can Ketogenic Diet Improve Alzheimer's Disease? Association With Anxiety, Depression, and Glutamate System.

de la Rubia Ortí JE, Fernández D, Platero F, García-Pardo MP · Frontiers in nutrition · 2021-10-27

Review

89. Ketogenic diet for depression: A potential dietary regimen to maintain euthymia?

Włodarczyk A, Cubała WJ, Stawicki M · Progress in neuro-psychopharmacology & biological psychiatry · 2021-01-23

Review

90. The use of the ketogenic diet in the treatment of psychiatric disorders.

Tillery EE, Ellis KD, Threatt TB, Reyes HA, Plummer CS, Barney LR · The mental health clinician · 2021-05-12

Observational human study

91. The psychiatric effects of ketogenic diet therapy on adults with chronic epilepsy.

Shegelman A, Carson KA, McDonald TJW, Henry-Barron BJ, Diaz-Arias LA, Cervenka MC · Epilepsy & behavior : E&B · 2021-02-18

Clinical trial / intervention

92. Ketogenic Diet: A Dietary Modification as an Anxiolytic Approach?

Włodarczyk A, Cubała WJ, Wielewicka A · Nutrients · 2020-12-14

Review

93. Mechanisms of insulin resistance, mitochondrial dysfunction and the action of the ketogenic diet in bipolar disorder. Focus on the PI3K/AKT/HIF1-a pathway.

Campbell I, Campbell H · Medical hypotheses · 2020-09-24

Review

94. The Ketogenic Diet for the Treatment of Mood Disorders in Comorbidity With Epilepsy in Children and Adolescents.

Operto FF, Matricardi S, Pastorino GMG, Verrotti A, Coppola G · Frontiers in pharmacology · 2020-11-24

Other

95. Ketogenic diet in bipolar disorder.

Saraga M, Misson N, Cattani E · Bipolar disorders · 2020-10-16

Review

96. Mental, emotional, and behavioral effects of ketogenic diet for non-epileptic neuropsychiatric conditions.

Grigolon RB, Gerchman F, Schöffel AC, Hawken ER, Gill H, Vazquez GH, Mansur RB, McIntyre RS, Brietzke E · Progress in neuro-psychopharmacology & biological psychiatry · 2020-04-17

Clinical trial / intervention

97. Anti-depression effects of ketogenic diet are mediated via the restoration of microglial activation and neuronal excitability in the lateral habenula.

Guan YF, Huang GB, Xu MD, Gao F, Lin S, Huang J, Wang J, Li YQ, Wu CH, Yao S, Wang Y, Zhang YL, Teoh JP, Xuan A, Sun XD · Brain, behavior, and immunity · 2020-05-12

Preclinical / mechanistic

98. Gestational exposure to a ketogenic diet increases sociability in CD-1 mice.

Arqoub AMS, Flynn KG, Martinez LA · Behavioral neuroscience · 2020-03-30

Preclinical / mechanistic

99. Effects of beta-hydroxybutyrate administration on MK-801-induced schizophrenia-like behaviour in mice.

Kraeuter AK, Mashavave T, Suvarna A, van den Buuse M, Sarnyai Z · Psychopharmacology · 2020-01-28

Preclinical / mechanistic

100. Preclinical testing of the ketogenic diet in fragile X mice.

Westmark PR, Gutierrez A, Gholston AK, Wilmer TM, Westmark CJ · Neurochemistry international · 2020-01-17

Other

101. Mechanisms of action of the ketogenic diet in depression.

Włodarczyk A, Cubała WJ · Neuroscience and biobehavioral reviews · 2019-09-27

Preclinical / mechanistic

102. Ketogenic diet and olanzapine treatment alone and in combination reduce a pharmacologically-induced prepulse inhibition deficit in female mice.

Kraeuter AK, Archambault N, van den Buuse M, Sarnyai Z · Schizophrenia research · 2019-08-09

Randomized clinical trial

103. Ketogenic diet for schizophrenia: clinical implication.

Sarnyai Z, Kraeuter AK, Palmer CM · Current opinion in psychiatry · 2019-06-14

Case report / case series

104. The ketogenic diet and remission of psychotic symptoms in schizophrenia: Two case studies.

Palmer CM, Gilbert-Jaramillo J, Westman EC · Schizophrenia research · 2019-04-06

Clinical trial / intervention

105. Therapeutic Potential of Exogenous Ketone Supplement Induced Ketosis in the Treatment of Psychiatric Disorders: Review of Current Literature.

Kovács Z, D'Agostino DP, Diamond D, Kindy MS, Rogers C, Ari C · Frontiers in psychiatry · 2019-05-23

Preclinical / mechanistic

106. The effect of ketogenic diet on behaviors and synaptic functions of naive mice.

Huang J, Li YQ, Wu CH, Zhang YL, Zhao ST, Chen YJ, Deng YH, Xuan A, Sun XD · Brain and behavior · 2019-03-07

Clinical trial / intervention

107. Ketogenic diet prevents impaired prepulse inhibition of startle in an acute NMDA receptor hypofunction model of schizophrenia.

Kraeuter AK, van den Buuse M, Sarnyai Z · Schizophrenia research · 2018-11-20

Clinical trial / intervention

108. Ketogenic diets potentially reverse Type II diabetes and ameliorate clinical depression: A case study.

Cox N, Gibas S, Salisbury M, Gomer J, Gibas K · Diabetes & metabolic syndrome · 2019-02-06

Other

109. The influence of ketogenic diets on mood stability in bipolar disorder.

Dsouza A, Haque S, Aggarwal R · Asian journal of psychiatry · 2017-10-28

Clinical trial / intervention

110. Ketogenic diet as a metabolic therapy for mood disorders: Evidence and developments.

Brietzke E, Mansur RB, Subramaniapillai M, Balanzá-Martínez V, Vinberg M, González-Pinto A, Rosenblat JD, Ho R, McIntyre RS · Neuroscience and biobehavioral reviews · 2018-07-31

Other

111. Ketogenic diet for schizophrenia: Nutritional approach to antipsychotic treatment.

Włodarczyk A, Wiglusz MS, Cubała WJ · Medical hypotheses · 2018-06-20

Case report / case series

112. Ketogenic diet in the treatment of schizoaffective disorder: Two case studies.

Palmer CM · Schizophrenia research · 2017-02-03

Other

113. Impact of Child Life Services on Children and Families Admitted to Start the Ketogenic Diet.

Kossoff EH, Sutter L, Doerrer SC, Haney CA, Turner Z · Journal of child neurology · 2017-05-08

Preclinical / mechanistic

114. The effect of ketogenic diet in an animal model of autism induced by prenatal exposure to valproic acid.

Castro K, Baronio D, Perry IS, Riesgo RDS, Gottfried C · Nutritional neuroscience · 2016-02-08

Randomized clinical trial

115. The Current Status of the Ketogenic Diet in Psychiatry.

Bostock EC, Kirkby KC, Taylor BV · Frontiers in psychiatry · 2017-03-20

Other

116. Ketogenic diet reverses behavioral abnormalities in an acute NMDA receptor hypofunction model of schizophrenia.

Kraeuter AK, Loxton H, Lima BC, Rudd D, Sarnyai Z · Schizophrenia research · 2015-11-04

Preclinical / mechanistic

117. Ketogenic diet does not impair spatial ability controlled by the hippocampus in male rats.

Fukushima A, Ogura Y, Furuta M, Kakehashi C, Funabashi T, Akema T · Brain research · 2015-06-23

Preclinical / mechanistic

118. Gestational ketogenic diet programs brain structure and susceptibility to depression & anxiety in the adult mouse offspring.

Sussman D, Germann J, Henkelman M · Brain and behavior · 2014-12-29

Case report / case series

119. The ketogenic diet for type II bipolar disorder.

Phelps JR, Siemers SV, El-Mallakh RS · Neurocase · 2012-10-03

Review

120. Schizophrenia, gluten, and low-carbohydrate, ketogenic diets: a case report and review of the literature.

Kraft BD, Westman EC · Nutrition & metabolism · 2009-02-26

Preclinical / mechanistic

121. Effects of short-term and long-term treatment with medium- and long-chain triglycerides ketogenic diet on cortical spreading depression in young rats.

de Almeida Rabello Oliveira M, da Rocha Ataíde T, de Oliveira SL, de Melo Lucena AL, de Lira CE, Soares AA, de Almeida CB, Ximenes-da-Silva A · Neuroscience letters · 2008-01-19

Preclinical / mechanistic

122. The antidepressant properties of the ketogenic diet.

Murphy P, Likhodii S, Nylen K, Burnham WM · Biological psychiatry · 2004-02-27

Case report / case series

123. Ketogenic diet in bipolar illness.

Yaroslavsky Y, Stahl Z, Belmaker RH · Bipolar disorders · 2002-06-06

Clinical trial / intervention

124. The ketogenic diet may have mood-stabilizing properties.

El-Mallakh RS, Paskitti ME · Medical hypotheses · 2002-03-29

Preclinical / mechanistic

125. A possible mechanism for the anti-ketogenic action of alanine in the rat.

Nosadini R, Datta H, Hodson A, Alberti KG · The Biochemical journal · 1980-08-15

Preclinical / mechanistic

126. Metabolic adaptations and dietary preferences in mice exposed to ketogenic and high-fat high-sucrose diets.

Penna-de-Carvalho A, Nagagata BA, Guarnieri RS, Borges MMS, Teixeira LPM, Ferreira-Machado SC, Aguila MB · Nutrition (Burbank, Los Angeles County, Calif.) · 2025-11-23

Randomized clinical trial

127. Ketogenic diet is less effective in ameliorating depression and anxiety in obesity than Mediterranean diet: A pilot study for exploring the GUT-brain axis.

Mela V, Ortiz Samur NS, Vijaya AK, Gálvez VJ, García-Martín ML, Bandera B, Martínez-Montoro JI, Gómez-Pérez AM, Moreno-Indias I, Tinahones FJ · Brain, behavior, and immunity · 2025-11-04

Observational human study

128. Association between dietary ketogenic ratio and depressive symptoms: A population-based cross-sectional study using 2007-2018 NHANES data.

Zhuang X, Zhan Y, Feng X, Liu C · Journal of affective disorders · 2025-06-09

Case report / case series

129. Ketogenic Diet as Protection for Deprescribing Antipsychotics.

Schlimme JE · Schizophrenia bulletin · 2025-07-02

Clinical trial / intervention

130. Case series: Effects of a ketogenic diet on cardiometabolic health in seven outpatients with bipolar disorder.

Schreel L, Bürkle M, Thiem A, von Baehr V, Sauren J, Keferstein G · Frontiers in nutrition · 2025-10-07

Clinical trial / intervention

131. A pilot study examining a ketogenic diet as an adjunct therapy in college students with major depressive disorder.

Decker DD, Patel R, Cheavens J, Hayes SM, Whitted W, Lee AJ, Buga A, Robinson BT, Crabtree CD, Kackley ML, Stoner JT, Sapper TN, Chebbi A, Volek JS · Translational psychiatry · 2025-09-10

Observational human study

132. Association between ketogenic diets and depression: A cross-sectional analysis of the NHANES 2005-2023 August.

Ren H, Wang Z, Yuan Y, He Y, Li W, Ou Y, Zhang S, Chen S, Li J, Zeng Y, Liu Y · Journal of affective disorders · 2025-04-05

Clinical trial / intervention

133. Ketogenic therapy for schizophrenia: evidence, mechanisms, and clinical perspectives.

Chaves C, Fabe J, Gomes FA, McNeely H, Tusconi M, Carta MG, Dursun SM, Hallak JEC, Brietzke E · Frontiers in pharmacology · 2025-06-25

Observational human study

134. Case Report: Remission of schizophrenia using a carnivore ketogenic metabolic therapy with nutritional therapy practitioner support.

Newiss M · Frontiers in nutrition · 2025-06-24

Clinical trial / intervention

135. Remission of obsessive-compulsive disorder using ketogenic metabolic therapy in support of exposure and response prevention: a retrospective case report.

Laurent N, Tague KA · Frontiers in psychiatry · 2025-06-20

Randomized clinical trial

136. The Effect of Exogenous Ketones on Signs and Symptoms of Schizophrenia Spectrum and Bipolar Disorders: Study Protocol for a Triple-Blind, Randomized, Controlled Crossover Pilot Study.

Dielemans DA, Yurtkap Y, van der Pluijm M, Soeters MR, Oranje B, Smit DJ, Ziermans T, van Tricht MJ, Muthukumar S, Prasad S, van der Mieden van Opmeer RL, Dekeyster E, Kamperman AM, Dyck JR, Rosema BS, Hoekstra R, Kupka RW, de Haan L, van Beveren NJ, Huizer K · Current developments in nutrition · 2025-05-24

Clinical trial / intervention

137. Keto therapy-unveiling the potential of ketogenic diet in psychiatric care: A scoping review.

Boltri M, Scalia A, Brusa F, Manzo F, Apicella E, Mendolicchio L · Nutrition (Burbank, Los Angeles County, Calif.) · 2025-02-07

Clinical trial / intervention

138. The ketogenic diet and metabolic treatments for neuropsychiatric disorders.

Palmer CM · BJPsych open · 2025-05-09

Clinical trial / intervention

139. Ketogenic diet attenuates neuroinflammation and restores hippocampal neurogenesis to improve CUMS induced depression-like behavior in mice.

Liang J, Zhang J, Sun J, Liang Q, Zhan Y, Yang Z, Zhang Y, Jin L, Hu C, Zhao YT · Food & function · 2025-05-06

Review

140. Ketogenic diet, adenosine, and dopamine in addiction and psychiatry.

Ruskin DN, Martinez LA, Masino SA · Frontiers in nutrition · 2025-03-10

Clinical trial / intervention

141. Ketogenic metabolic therapy in the remission of chronic major depressive disorder: a retrospective case study.

Laurent N, Bellamy EL, Hristova D, Houston A · Frontiers in nutrition · 2025-02-27

Clinical trial / intervention

142. Ketogenic metabolic therapy for schizoaffective disorder: a retrospective case series of psychotic symptom remission and mood recovery.

Laurent N, Bellamy EL, Tague KA, Hristova D, Houston A · Frontiers in nutrition · 2025-02-07

Clinical trial / intervention

143. Perspectives on the ketogenic diet as a non-pharmacological intervention for major depressive disorder.

Shelp J, Chaves C, Terpstra A, Koning E, Gomes FA, Fabe J, Breda V, Laurent N, Palmer C, Brietzke E · Trends in psychiatry and psychotherapy · 2025-03-21

Other

144. A PILOT STUDY OF THE KETOGENIC DIET IN SCHIZOPHRENIA.

PACHECO A, EASTERLING WS, PRYER MW · The American journal of psychiatry · 1965-05-01

Substance Use Disorders Recent peer-reviewed literature

Only directly relevant publications are displayed. Automated search results are not used as bibliography.

Curated references (3)

Ketogenic diet reduces a neurobiological craving signature in inpatients with alcohol use disorder

Front Nutr · 2024 · Secondary analysis of randomized inpatient intervention

Ketogenic diet: a potential adjunctive treatment for substance use disorders

Front Nutr · 2023 · Review

Nutritional Ketosis as a Potential Treatment for Alcohol Use Disorder

Front Psychiatry · 2021 · Review

Preclinical study

4. Effects of Ketogenic Diet on Increased Ethanol Consumption Induced by Social Stress in Female Mice

Original publication title: Effects of Ketogenic Diet on Increased Ethanol Consumption Induced by Social Stress in Female Mice

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Clinical / translational evidence

5. Ketogenic Diet Improves Alcohol Withdrawal

Original publication title: Ketogenic Diet Improves Alcohol Withdrawal

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Human + preclinical study

6. Ketone Supplementation Dampens Subjective and Objective Responses to Alcohol in Rats and Humans

Original publication title: Ketone Supplementation Dampens Subjective and Objective Responses to Alcohol in Rats and Humans

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Preclinical study

7. Ketogenic Diet Enhances the Effects of Oxycodone in Mice

Original publication title: Ketogenic Diet Enhances the Effects of Oxycodone in Mice

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Clinical trial / intervention

8. From diet to drinking behavior: Ketogenic diet decreases ethanol intake in young adult female mice.

Torres-Rubio L, Mellado S, Montagud-Romero S, Pascual M, Rodríguez-Arias M · Behavioural brain research · 2026-09-05

Clinical trial / intervention

9. Short-term ketogenic diet induces systemic lipidomic remodeling associated with metabolic adaptation in humans.

Park M, Yu JS, Jeon JY, Oh HA, Lee YH, Lee SG, Lee G · Frontiers in nutrition · 2026-07-10

Preclinical / mechanistic

10. A ketogenic diet reduces hepatic alcohol metabolism and alcohol consumption in rats.

Elvig SK, McGinn A, Li X, Vendruscolo JCM, Gomez JL, Pawlosky R, Mackowiak B, Gonzalez L, King MT, Michaelides M, Gao B, Volkow ND, Koob GF, Wiers CE, Vendruscolo LF · Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026-03-20

Randomized clinical trial

11. Pharmacokinetic effects of a single dose nutritional ketone ester supplement on brain glucose and ketone metabolism in alcohol use disorder.

Li X, Young AJ, Shi Z, Byanyima J, Vesslee S, Reddy R, Pond T, Elliott M, Reddy R, Doot RK, van der Veen JW, Kranzler HR, Nanga RPR, Dubroff JG, Wiers CE · Psychiatry research. Neuroimaging · 2026-01-29

Preclinical / mechanistic

12. The Effects of Eating a Traditional High Fat/High Carbohydrate or a Ketogenic Diet on Sensitivity of Female Rats to Morphine.

Beltran NM, Parra AN, Serrano AP, Castillo J, Castro IM, Elsey MK, Minervini V, Serafine KM · The Journal of pharmacology and experimental therapeutics · 2024-09-18

Preclinical / mechanistic

13. The ketogenic diet mitigates opioid-induced hyperalgesia by restoring short-chain fatty acids-producing bacteria in the gut.

Crawford J, Liu S, Tao R, Kramer P, Bender S, Tao F · Pain · 2024-03-06

Preclinical / mechanistic

14. Nutritional ketosis as treatment for alcohol withdrawal symptoms in female C57BL/6J mice.

Tonetto S, Weikop P, Thomsen M · Scientific reports · 2024-03-01

Case report / case series

15. Correction: Treating binge eating and food addiction symptoms with low-carbohydrate Ketogenic diets: a case series.

Carmen M, Safer DL, Saslow LR, Kalayjian T, Mason AE, Westman EC, Sethi S · Journal of eating disorders · 2023-09-29

Randomized clinical trial

16. Ketogenic diet reduces a neurobiological craving signature in alcohol use disorder.

Wiers CE, Manza P, Wang GJ, Volkow ND · medRxiv : the preprint server for health sciences · 2023-09-26

Randomized clinical trial

17. Brain glutamate and sleep efficiency associations following a ketogenic diet intervention in individuals with Alcohol Use Disorder.

Li X, Shi Z, Byanyima J, Morgan PT, van der Veen JW, Zhang R, Deneke E, Wang GJ, Volkow ND, Wiers CE · Drug and alcohol dependence reports · 2022-09-08

Other

18. Very-Low-Calorie Ketogenic Diet: A Potential Treatment for Binge Eating and Food Addiction Symptoms in Women. A Pilot Study.

Rostanzo E, Marchetti M, Casini I, Aloisi AM · International journal of environmental research and public health · 2021-12-04

Clinical trial / intervention

19. Ketogenic Diet Decreases Alcohol Intake in Adult Male Mice.

Blanco-Gandía MDC, Ródenas-González F, Pascual M, Reguilón MD, Guerri C, Miñarro J, Rodríguez-Arias M · Nutrients · 2021-06-24

Randomized clinical trial

20. Ketogenic diet reduces alcohol withdrawal symptoms in humans and alcohol intake in rodents.

Wiers CE, Vendruscolo LF, van der Veen JW, Manza P, Shokri-Kojori E, Kroll DS, Feldman DE, McPherson KL, Biesecker CL, Zhang R, Herman K, Elvig SK, Vendruscolo JCM, Turner SA, Yang S, Schwandt M, Tomasi D, Cervenka MC, Fink-Jensen A, Benveniste H, Diazgranados N, Wang GJ, Koob GF, Volkow ND · Science advances · 2021-04-09

Preclinical / mechanistic

21. Effects of ketogenic diet and ketone monoester supplement on acute alcohol withdrawal symptoms in male mice.

Bornebusch AB, Mason GF, Tonetto S, Damsgaard J, Gjedde A, Fink-Jensen A, Thomsen M · Psychopharmacology · 2021-01-07

Case report / case series

22. Low carbohydrate ketogenic therapy as a metabolic treatment for binge eating and ultraprocessed food addiction.

Sethi S, Sinha A, Gearhardt AN · Current opinion in endocrinology, diabetes, and obesity · 2020-08-11

Case report / case series

23. A Case of Hypoglycemia Associated With the Ketogenic Diet and Alcohol Use.

Spoke C, Malaeb S · Journal of the Endocrine Society · 2020-04-18

Case report / case series

24. Treating binge eating and food addiction symptoms with low-carbohydrate Ketogenic diets: a case series.

Carmen M, Safer DL, Saslow LR, Kalayjian T, Mason AE, Westman EC, Sethi S · Journal of eating disorders · 2020-01-29

Preclinical / mechanistic

25. Ketogenic Diet Suppresses Alcohol Withdrawal Syndrome in Rats.

Dencker D, Molander A, Thomsen M, Schlumberger C, Wortwein G, Weikop P, Benveniste H, Volkow ND, Fink-Jensen A · Alcoholism, clinical and experimental research · 2017-12-23

Preclinical / mechanistic

26. Ketogenic diet is antiepileptogenic in pentylenetetrazole kindled mice and decrease levels of N-acylethanolamines in hippocampus.

Hansen SL, Nielsen AH, Knudsen KE, Artmann A, Petersen G, Kristiansen U, Hansen SH, Hansen HS · Neurochemistry international · 2008-11-30

Case report / case series

27. False-positive breath-alcohol test after a ketogenic diet.

Jones AW, Rössner S · International journal of obesity (2005) · 2006-08-08

Other

28. Carbohydrate and alcohol content of 200 oral liquid medications for use in patients receiving ketogenic diets.

Feldstein TJ · Pediatrics · 1996-04-01

Preclinical / mechanistic

29. Eating a high fat/high carbohydrate diet enhances morphine tolerance, while eating a ketogenic diet mitigates morphine withdrawal in male rats.

Beltran NM, Sullivan LL, Naime GM, Minervini V, Serafine KM · European journal of pharmacology · 2025-05-08

Review

30. Ketogenic diet, adenosine, and dopamine in addiction and psychiatry.

Ruskin DN, Martinez LA, Masino SA · Frontiers in nutrition · 2025-03-10

Review

31. A ketogenic diet regulates microglial activation to treat drug addiction.

Ji J, Tang Y · Frontiers in pharmacology · 2025-01-23

Eating Disorders Recent peer-reviewed literature

Source-audited selection from the connected PDF archive. Systematic reviews/meta-analyses and recent human evidence are prioritized when available; sparse areas are explicitly kept sparse.

Direct clinical evidence

1. A Ketogenic Diet for the Management of Binge-Eating Disorder

Original publication title: A Ketogenic Diet for the Management of Binge-Eating Disorder

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Clinical hypothesis/review

2. Providing Alternative Fuel for the Brain in Anorexia Nervosa

Original publication title: Providing Alternative Fuel for the Brain in Anorexia Nervosa

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Review / case-based evidence

3. Synergy Between Ketamine and Ketogenic Diet in Anorexia Nervosa and Other Neurobehavioral Disorders

Original publication title: Synergy Between Ketamine and Ketogenic Diet in Anorexia Nervosa and Other Neurobehavioral Disorders

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Clinical evidence

4. Ketogenic Diet and Ketamine Infusion Treatment in Anorexia Nervosa

Original publication title: Ketogenic Diet and Ketamine Infusion Treatment in Anorexia Nervosa

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Clinical evidence

5. Very-Low-Calorie Ketogenic Diet: A Potential Treatment for Binge-Eating Symptoms in Obesity

Original publication title: Very-Low-Calorie Ketogenic Diet: A Potential Treatment for Binge-Eating Symptoms in Obesity

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Clinical / hypothesis evidence

6. Therapeutic Ketogenic Diet as Treatment for Anorexia Nervosa

Original publication title: Therapeutic Ketogenic Diet as Treatment for Anorexia Nervosa

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Preclinical / mechanistic

7. Ketamine enhances ketogenic diet-induced resilience to activity-based anorexia of adult mice through hippocampal synaptic plasticity.

Wang J, Ge O, Dong Y, Lee E, Aoki C · Neuroscience · 2026-09-01

Clinical trial / intervention

8. Symptom impact and safety of ketogenic therapy in adults with anorexia nervosa: a feasibility trial.

Frank GKW, Scolnick B, Beckwith C, Shott ME, Kilty S, Swindle S, Lutter M, Rho JM · Communications medicine · 2026-06-03

Other

9. A ketogenic diet for the management of binge-eating disorder: a pilot study.

Liang Y, Taylor A, Haas V, Qiu C · Eating and weight disorders : EWD · 2026-03-26

Preclinical / mechanistic

10. Ketogenic Food Ameliorates Activity-Based Anorexia of Adult Female Mice.

Dong Y, Lin Y, Khatri L, Chao M, Aoki C · The International journal of eating disorders · 2024-11-16

Case report / case series

11. Correction: Treating binge eating and food addiction symptoms with low-carbohydrate Ketogenic diets: a case series.

Carmen M, Safer DL, Saslow LR, Kalayjian T, Mason AE, Westman EC, Sethi S · Journal of eating disorders · 2023-09-29

Clinical trial / intervention

12. Ketogenic diet and ketamine infusion treatment to target chronic persistent eating disorder psychopathology in anorexia nervosa: a pilot study.

Calabrese L, Scolnick B, Zupec-Kania B, Beckwith C, Costello K, Frank GKW · Eating and weight disorders : EWD · 2022-08-23

Review

13. Helpful or harmful? The impact of the ketogenic diet on eating disorder outcomes in type 1 diabetes mellitus.

Schneider S, Biggerstaff DL, Barber TM · Expert review of endocrinology & metabolism · 2022-06-24

Other

14. Very-Low-Calorie Ketogenic Diet: A Potential Treatment for Binge Eating and Food Addiction Symptoms in Women. A Pilot Study.

Rostanzo E, Marchetti M, Casini I, Aloisi AM · International journal of environmental research and public health · 2021-12-04

Case report / case series

15. Low carbohydrate ketogenic therapy as a metabolic treatment for binge eating and ultraprocessed food addiction.

Sethi S, Sinha A, Gearhardt AN · Current opinion in endocrinology, diabetes, and obesity · 2020-08-11

Case report / case series

16. Remission from Chronic Anorexia Nervosa With Ketogenic Diet and Ketamine: Case Report.

Scolnick B, Zupec-Kania B, Calabrese L, Aoki C, Hildebrandt T · Frontiers in psychiatry · 2020-07-30

Case report / case series

17. Treating binge eating and food addiction symptoms with low-carbohydrate Ketogenic diets: a case series.

Carmen M, Safer DL, Saslow LR, Kalayjian T, Mason AE, Westman EC, Sethi S · Journal of eating disorders · 2020-01-29

Other

18. Ketogenic diet and anorexia nervosa.

Scolnick B · Medical hypotheses · 2017-10-13

Oncology

Oncology & Cancer Metabolism Recent peer-reviewed literature

Expanded source-audited selection. Systematic reviews/meta-analyses and recent human evidence are placed first; older clinical and mechanistic papers follow.

Systematic review & meta-analysis

1. Effect of Ketogenic Diets on Body Composition and Metabolic Parameters of Cancer Patients: A Systematic Review and Meta-Analysis

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Recent human clinical study · 2026

2. Very low-carbohydrate ketogenic diet in treatment-naïve women with endometrial cancer

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Recent clinical review · 2026

3. How the Ketogenic Diet Shapes the Microbiome to Influence Cancer Immunotherapy Outcomes: An Exploration of Clinical Trials and Their Results

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Recent disease-focused review · 2026

4. The Role of the Ketogenic Diet in Lung Cancer

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Recent mechanistic study · 2026

5. Ketogenic Diet Alleviates Colorectal Cancer by Attenuating Macrophage M2 Polarisation

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Recent translational study · 2026

6. Ketogenic Diet and β-Hydroxybutyrate Suppress Bladder Cancer Growth and Enhance Anti-PD-L1

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Recent cancer study

7. Ketogenic diet prevents obesity-associated pancreatic cancer independent of weight loss

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Recent cancer study

8. Ketogenic diet suppresses colorectal cancer

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Recent review

9. Overcoming immunosuppression in cancer: how ketogenic diets may boost anti-tumor immunity

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Human clinical study

10. Weight Loss, Pathological Changes, and Inflammatory Effects from a Short-Term Ketogenic Diet in Overweight and Obese Men with Untreated Prostate Cancer on Active Surveillance

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Translational study

11. A Ketogenic Diet Sensitizes Pancreatic Cancer to Inhibition of Glutamine Metabolism

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Review

12. Ketogenic diet in cancer therapy

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Review

13. Effects of ketogenic diet on oxidative stress and cancer

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Translational study

14. Ketogenic diet enhances the anti-cancer effects of PD-L1 blockade in renal cell carcinoma

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Translational study

15. Ketogenic diet alters the epigenetic and immune landscape of prostate cancer

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Preclinical study

16. A ketogenic diet rich in fish oil is superior to other fats in preventing NNK-induced lung cancer

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Review

17. What We Have Learned About Combining a Ketogenic Diet and Chemoimmunotherapy

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Review

18. Cancer Metabolism as a Therapeutic Target and Review of Interventions

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Review

19. Current knowledge in pharmaconutrition: ketogenics in pediatric gliomas

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Clinical pilot study

20. ERGO: a pilot study of ketogenic diet in recurrent glioblastoma

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Long-term clinical evidence

21. Long-Term Effects of a Ketogenic Diet for Cancer

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Review

22. Ketogenic Diet in the Treatment of Gliomas and Glioblastomas

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Case report

23. Restricted Ketogenic Diet Therapy for Primary Lung Cancer With Metastasis to the Brain

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Review

24. Ketogenic Metabolic Therapy for Glioma

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Review

25. Ketogenic diet: new avenues to overcome colorectal cancer

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Review

26. Ketogenic Diets in Pancreatic Cancer and Associated Cachexia

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Review

27. Ketogenic Diet in Cancer Prevention and Therapy: Molecular Mechanisms

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Critical review

28. Ketogenic Diet for Cancer: Critical Assessment

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Review

29. Effects of the Ketogenic Diet in the Treatment of Gliomas

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Mechanistic review

30. Molecular Mechanisms for Ketone Body Metabolism, Signaling Functions, and Therapeutic Potential in Cancer

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Mechanistic / translational review

31. β-Hydroxybutyrate and Malignant Neoplasms

Original publication title: β-Hydroxybutyrate and Malignant Neoplasms

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Preclinical study

32. Metabolic Intervention by Low-Carbohydrate Diet Suppresses the Onset and Progression of Neuroendocrine Tumors

Original publication title: Metabolic Intervention by Low-Carbohydrate Diet Suppresses the Onset and Progression of Neuroendocrine Tumors

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Preclinical combination-therapy study

33. Triple Therapy With Metformin, Ketogenic Diet, and Metronomic Cyclophosphamide Reduced Tumor Growth in MYCN-Amplified Neuroblastoma Xenografts

Original publication title: Triple Therapy With Metformin, Ketogenic Diet, and Metronomic Cyclophosphamide Reduced Tumor Growth in MYCN-Amplified Neuroblastoma Xenografts

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Preclinical study

34. Anti-Tumor Effect of the Ketogenic Diet Against DMH-Induced Colon Cancer

Original publication title: Anti-Tumor Effect of the Ketogenic Diet Against DMH-Induced Colon Cancer

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Preclinical study

35. Ketogenic Diets Slow Melanoma Growth

Original publication title: Ketogenic Diets Slow Melanoma Growth

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Disease-focused review

36. Ketogenic Diets and Hepatocellular Carcinoma

Original publication title: Ketogenic Diets and Hepatocellular Carcinoma

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Preclinical glioma study

37. The Efficacy of an Unrestricted Cycling Ketogenic Diet in Preclinical Models of IDH Wild-Type and IDH-Mutant Glioma

Original publication title: The Efficacy of an Unrestricted Cycling Ketogenic Diet in Preclinical Models of IDH Wild-Type and IDH-Mutant Glioma

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Preclinical / translational study

38. Ketogenic Diet and Chemotherapy Combine to Improve Antitumor Effects

Original publication title: Ketogenic Diet and Chemotherapy Combine to Improve Antitumor Effects

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Mechanistic cancer study

39. Ketogenesis Attenuates KLF5-Dependent Production of CXCL12 to Overcome Tumor-Promoting Signaling

Original publication title: Ketogenesis Attenuates KLF5-Dependent Production of CXCL12 to Overcome Tumor-Promoting Signaling

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Review

40. Dietary Interventions in Cancer Treatment and Response

Original publication title: Dietary Interventions in Cancer Treatment and Response

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Systematic review & meta-analysis

41. Efficacy and Safety of Ketogenic Diet in Glioblastoma: An Updated Systematic Review and Meta-Analysis

Original publication title: Efficacy and Safety of Ketogenic Diet in Glioblastoma: An Updated Systematic Review and Meta-Analysis

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Systematic review of clinical trials

42. Efficacy of Ketogenic Metabolic Therapy as an Adjuvant to the Current Standard of Care in the Treatment of Glioblastoma: A Systematic Review of Clinical Trials

Original publication title: Efficacy of Ketogenic Metabolic Therapy as an Adjuvant to the Current Standard of Care in the Treatment of Glioblastoma: A Systematic Review of Clinical Trials

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Human clinical study

43. Successful Application of Dietary Ketogenic Metabolic Therapy in Patients with Glioblastoma: A Clinical Study

Original publication title: Successful Application of Dietary Ketogenic Metabolic Therapy in Patients with Glioblastoma: A Clinical Study

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Human clinical trial

44. Feasibility and Metabolic Outcomes of a Well-Formulated Ketogenic Diet as an Adjuvant Therapeutic Intervention for Women with Stage IV Metastatic Breast Cancer: The Keto-CARE Trial

Original publication title: Feasibility and Metabolic Outcomes of a Well-Formulated Ketogenic Diet as an Adjuvant Therapeutic Intervention for Women with Stage IV Metastatic Breast Cancer: The Keto-CARE Trial

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Disease-focused review

45. Ketogenic Diet and Breast Cancer: Recent Findings and Therapeutic Approaches

Original publication title: Ketogenic Diet and Breast Cancer: Recent Findings and Therapeutic Approaches

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Clinical / translational evidence

46. Ketogenic Metabolic Therapy in Conjunction with Standard Treatment for Glioblastoma

Original publication title: Ketogenic Metabolic Therapy in Conjunction with Standard Treatment for Glioblastoma

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Clinical research framework

47. Clinical Research Framework Proposal for Ketogenic Metabolic Therapy in Glioblastoma

Original publication title: Clinical Research Framework Proposal for Ketogenic Metabolic Therapy in Glioblastoma

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Mechanistic review

48. The Influence of the Ketogenic Diet on the Immune Tolerant Microenvironment in Glioblastoma

Original publication title: The Influence of the Ketogenic Diet on the Immune Tolerant Microenvironment in Glioblastoma

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Preclinical study

49. Ketogenic Diet with Oxyresveratrol and Zinc Inhibits Glioblastoma and Restores Memory Function and Motor Coordination

Original publication title: Ketogenic Diet with Oxyresveratrol and Zinc Inhibits Glioblastoma and Restores Memory Function and Motor Coordination

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Disease-focused review

50. The Role of Ketogenic Diet in the Treatment of Neuroblastoma

Original publication title: The Role of Ketogenic Diet in the Treatment of Neuroblastoma

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Clinical trial / intervention

51. The Ketogenic Diet as Adjunctive Strategy in Cancer Treatment-Therapeutic Benefits and Metabolic Risk Using Breast Cancer as an Example.

Szołtysek J, Szymańska B, Piwowar A · Nutrients · 2026-09-06

Other

52. Ketogenic Diet Promotes Intestinal Tumorigenesis Via Lipid Oxidation.

Cancer discovery · 2026-08-25

Clinical trial / intervention

53. Ketogenic Diet as an Adjuvant in Epithelial Cancers: Mechanisms, Model Systems, and Translational Opportunities.

Ylikomi T, Nees M · Cancers · 2026-08-12

Randomized clinical trial

54. Metabolic Therapy in Glioblastoma-Mapping the Evidence for Ketogenic Diet as an Adjunctive Strategy.

Wiśniewska D, Winiarska M, Krupa-Nurcek S · Nutrients · 2026-08-03

Other

55. Correction to "Metabolism-Based Molecular Subtyping Endows Effective Ketogenic Therapy in p53-Mutant Colon Cancer".

Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026-07-31

Clinical trial / intervention

56. Integrative Multi-Omics Reveal Metabolic Reprogramming by Ketogenic Diet in Melanoma Xenografts.

Dnyansagar R, Bordag N, Poupardin R, Tevini J, Stefan VE, Derdak S, Bilban M, Fortelny N, Kofler B, Lang R, Weber DD · Biomolecules · 2026-07-22

Preclinical / mechanistic

57. Ketogenic diet mediates intestinal tumorigenesis through lipids not ketones.

Shay JES, Chi F, Tzouanas CN, Han S, Zhang X, Ten Hoeve J, Williams KJ, Neptun S, Sever T, Fuentes I, Bhatia SN, Calibasi-Kocal G, Vander Heiden MG, Shalek AK, Yilmaz ÖH · Nature · 2026-07-15

Systematic review / meta-analysis

58. Ketogenic Diet in the Treatment of Malignant Gliomas: A Systematic Review.

Persiani M, Dallolio L, Masini A, Longobucco Y, Bertoli S, Guberti E, Pellizzari M, Petroni ML, Valeriani F, Gallè F, Sacchetti R · Nutrients · 2026-07-03

Clinical trial / intervention

59. Intensive multimodal ketogenic metabolic therapy in glioblastoma: A clinical trial.

Phillips MCL, Thotathil Z, Haji Mohd Yasin NAB, de Groot C, Tan A, Kuper-Hommel M, Creagh LA, Ji E, Naidoo N, van Essen M, Ziad F, Moon BG, Frampton C, Jameson MB · Neuro-oncology advances · 2026-06-29

Other

60. Real-world safety, prognostic, and design considerations in ketogenic diet trials for pancreatic cancer.

Bruckner HW, Knopf E · Cancer · 2026-06-29

Other

61. Ketogenic Diet Alleviates Colorectal Cancer by Attenuating Macrophage M2 Polarisation Triggered by Oncometabolite MMA Derived From the Gut Microbiota.

Lu Y, Shi B, Chen J, Yao H, Mi X, Shao M, Zhao Y, Meng L, Tai Q, Chen J, Shi X, Zhou D, Yao Y, He S · Cell proliferation · 2026-06-17

Clinical trial / intervention

62. Ketogenic Diet and β-Hydroxybutyrate Suppress Bladder Cancer Growth and Enhance Anti-PD-L1 Immunotherapy Efficacy.

Zeng Y, Gu G, Yang L, Fan B, Cui H, Yan L, Liu Z · Cancer science · 2026-06-11

Clinical trial / intervention

63. [Long-Term Survival in Three Cases with Pulmonary Metastases from Colorectal Cancer Given Low-Dose S-1 Under a Regimen Combining a Carbohydrate-Restricted Ketogenic Diet, Metformin, Vitamin D, Eicosapentaenoic Acid, and Other Complementary Therapies].

Yamazaki F, Saegusa Y, Kobayashi M, Murata N, Moriya T, Miyazaki M · Gan to kagaku ryoho. Cancer & chemotherapy · 2026-06-07

Randomized clinical trial

64. Feasibility and Safety of a Ketogenic Diet During Systemic Therapy for Metastatic Renal Cell Carcinoma: Results from the Cetorein Pilot Study.

Rolley C, Zidane M, Nedelcu C, Barth M, Saulnier P, Procaccio V, Bigot P · Nutrients · 2026-05-27

Randomized clinical trial

65. Very low-carbohydrate ketogenic diet in treatment-naïve women with endometrial cancer and overweight: a randomized feasibility study.

Dantas E, Hootman KC, Moyer J, Tomberlin M, Curran K, Ramesh B, Price H, Kim J, McPherson AC, Hurd MA, Zhu YS, Plodkowski AJ, Nagase E, Tsomides A, Cuevas BM, Martin ML, Nguyen J, Bennetti G, Rodriguez GB, Chang K, Mezzancello M, Gardner GJ, Broach V, Mueller JJ, Sonoda Y, Zivanovic O, Leitao MM, Iasonos A, Soldan K, Carthew K, Hom V, Villamater FN, Chaari RR, Gorski K, Sigouros M, Aghajanian C, Elemento O, Cantley LC, Hopkins BD, Weigelt B, Ellenson LH, Hacker K, Abu-Rustum NR, Makker V, Goncalves MD · Nature communications · 2026-05-27

Randomized clinical trial

66. Ketogenic and Low-Carbohydrate Diets in Prostate Cancer: Metabolic Rationale, Preclinical Evidence, and Preliminary Clinical Data.

Manfrini S, Malgeri A, Mone C, Francesco LD, Pecora G, Mazzilli R, Defeudis G, Khazrai MY, Faggiano A · Journal of clinical medicine · 2026-05-20

Other

67. Reply to "Real-world safety, prognostic, and design considerations in ketogenic diet trials for pancreatic cancer".

Hanna DL, Roberts CGP, Jameson GS, Roe DJ, Borazanci E, Zoller AR, Rabinowitz JD, Gately S, Von Hoff DD, Rasco DW · Cancer · 2026-05-16

Clinical trial / intervention

68. A ketogenic diet sensitizes pancreatic cancer to glutamine metabolism inhibitors.

Hajihassani O, Roichman A, Boyer JA, MacArthur M, Cordova R, Loftus A, Boutros CS, Hue JJ, Naji P, Tahhan S, Gallagher P, Beegan W, Shah D, Choi J, Manzoor N, Lei S, Kim C, Rathore M, Shah I, Lebo K, Cheng H, Mudigonda A, Hunter C, Zarei M, Alibeckoff S, Ji K, Graor H, Miyagi M, Vaziri-Gohar A, Brunengraber H, Wang R, Lund PJ, Rothermel LD, Rabinowitz JD, Winter JM · Cell reports. Medicine · 2026-04-23

Clinical trial / intervention

69. The Role of the Ketogenic Diet in Lung Cancer: Current Evidence and Future Perspectives.

Eleftheriadou ED, Kotoulas SC, Grammatikopoulou MG, Karakousi A, Maria A, Trimpali A, Tsalampounis X, Evangelidis P, Vamvakis A, Pataka A, Spyratos D · Cancers · 2026-04-17

Clinical trial / intervention

70. Ketogenic Diet: A Metabolic Key to Overcoming Cancer Therapy Resistance.

Sulaiman SH, Omer RA, Barzani KIS, Jawhar ZH, Barzani HAH · Molecular nutrition & food research · 2026-03-29

Preclinical / mechanistic

71. Targeting systemic and tumor metabolic balances with ketogenic diets enhance efficacy of therapy in FLT3-ITD acute myeloid leukemia.

Goupille L, Boudet A, Lauture L, Sahal A, Gautier-Renard G, Chu-Van E, Nguyen AL, Chollet C, Alcazar C, Bernard I, Vergez F, de Mas V, Récher C, Kaoma T, Gallipoli P, Dembitz V, Basili I, Bernardi F, Ayrault O, Joffre C, Castelli F, Colsch B, Bourgès-Abella N, Granat F, Sarry JE · Cell reports · 2026-03-28

Preclinical / mechanistic

72. Sexual dimorphism shapes renal metabolic adaptation to a ketogenic diet.

Kelly ME, Hoffner LA, Ramirez CB, Anica AL, Kim J, Tong G, Kim Y, Mannepalli V, Choi W, Jang KH, Alam YH, Jung S, Le J, Lopez ML, Rubtsova VI, Bae H, Chun Y, Song WS, Tamburini IJ, Schuster VL, Anton-Culver H, Lau WL, Martinez TF, Lee G, Jang C · Cell reports · 2026-03-28

Other

73. β-catenin mutation reprograms ketone body metabolism to drive hepatocellular carcinoma metastasis and resistance to ketogenic therapy via transcriptional activation of OXCT1.

Li H, Qian L, Ji Y, Geng Y, Lu Y, Zhang L, Xu Y, Zong W, Jiang X, Zhou X, Wen J, Liu D, Wang Y, Li Y, Li B, Ma H, Yu D · Cell death & disease · 2026-03-09

Clinical trial / intervention

74. Ketogenic diet modulates AMPK-mTOR pathway in breast cancer.

Luo Y, Li J, Yang Y, Yan L, Huang Z, Chen L, Zhao L, Wang J, Yang Y, Liu X, Yang X · The Journal of nutritional biochemistry · 2026-02-11

Preclinical / mechanistic

75. A2 astrocyte polarization mediates ketogenic diet protection of blood-central nervous system barriers in experimental autoimmune encephalomyelitis.

Zhang Q, Zheng M, Siebert HC, Wang Q, Zhang R, Zhang N · Neural regeneration research · 2025-12-30

Observational human study

76. Survival outcomes of rectal and head and neck cancer patients receiving radio(chemo)therapy with a ketogenic diet. A post-hoc analysis from the KETOCOMP trial.

Klement RJ, Sweeney RA · Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2025-12-17

Randomized clinical trial

77. A randomized phase II trial of gemcitabine, nab-paclitaxel, cisplatin with or without a medically supervised ketogenic diet for patients with metastatic pancreatic cancer.

Jameson GS, Roe DJ, Borazanci E, Hanna DL, Roberts CGP, Pelster MS, Frank RC, Alistar AT, Miller AM, Wiedmeier-Nutor JE, Algaze SD, Zoller AR, Hallberg SJ, Wertheim BC, Lee K, Cridebring D, Rabinowitz JD, Gately S, Keppler J, Sharma S, Von Hoff DD, Rasco DW · Cancer · 2025-12-05

Preclinical / mechanistic

78. Ketogenic diet as a metabolic vehicle enhancing the therapeutic efficacy of mebendazole and devimistat in juvenile syngeneic high-grade glioma.

Mukherjee P, Maurer J, Stopka SA, Greenwood B, Aristizabal-Henao JJ, Karmacharya S, Chimento A, Ta N, Lee DC, Duraj T, Bronson RT, Kiebish MA, Seyfried TN · Cell reports. Medicine · 2025-11-25

Review

79. The effects of the ketogenic diet on cancer treatment: a narrative review.

Deng Q, Lv R, Zou T · European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) · 2024-09-20

Preclinical / mechanistic

80. The ketogenic diet modulates tumor-associated neutrophil polarization via the AMOT-YAP/TAZ axis to inhibit colorectal cancer progression.

Mi X, Duan Y, Sun J, Tai Q, Yao H, Meng L, Yang X, Shi X, Shi B, Chen J, Sun L, Zhou D, Xiao S, Yao Y, He S · Pharmacological research · 2024-11-05

Preclinical / mechanistic

81. The Impact of a Ketogenic Diet on Late-Stage Pancreatic Carcinogenesis in Mice: Efficacy and Safety Studies.

Cortez NE, Bacha TA, Ead AS, Rodriguez Lanzi C, Lacroix C, Franceschetti A, Hong BV, Matsukuma K, Mackenzie GG · Nutrients · 2024-11-16

Review

82. Overcoming immunosuppression in cancer: how ketogenic diets boost immune checkpoint blockade.

Stefan VE, Weber DD, Lang R, Kofler B · Cancer immunology, immunotherapy : CII · 2024-11-13

Randomized clinical trial

83. An Exogenous Ketone Ester Slows Tumor Progression in Murine Breast and Renal Cancer Models.

Ogbonna HN, Roberts Z, Godwin N, Muri P, Turbitt WJ, Swalley ZN, Dempsey FR, Stephens HR, Zhang J, Plaisance EP, Norian LA · Cancers · 2024-10-04

Other

84. Metabolomics reveals the implication of acetoacetate and ketogenic diet therapy in radioiodine-refractory differentiated thyroid carcinoma.

Wang J, Xu Q, Xuan Z, Mao Y, Tang X, Yang K, Song F, Zhu X · The oncologist · 2024-01-05

Systematic review / meta-analysis

85. Effects of ketogenic diets on cancer-related variables: A systematic review and meta-analysis of randomised controlled trials.

Salido-Bueno B, Gil-Hernandez E, Rueda-Ruzafa L, Gomez-Chica P, Roman P, Cardona D · Nutrition bulletin · 2024-06-24

Systematic review / meta-analysis

86. Systematic Review and Clinical Insights: The Role of the Ketogenic Diet in Managing Glioblastoma in Cancer Neuroscience.

Valerio J, Borro M, Proietti E, Pisciotta L, Olarinde IO, Fernandez Gomez M, Alvarez Pinzon AM · Journal of personalized medicine · 2024-08-31

Preclinical / mechanistic

87. Ketogenic diet reshapes cancer metabolism through lysine β-hydroxybutyrylation.

Qin J, Huang X, Gou S, Zhang S, Gou Y, Zhang Q, Chen H, Sun L, Chen M, Liu D, Han C, Tang M, Feng Z, Niu S, Zhao L, Tu Y, Liu Z, Xuan W, Dai L, Jia D, Xue Y · Nature metabolism · 2024-08-12

Preclinical / mechanistic

88. An unexpected role for the ketogenic diet in triggering tumor metastasis by modulating BACH1-mediated transcription.

Su Z, Liu Y, Xia Z, Rustgi AK, Gu W · Science advances · 2024-06-05

Preclinical / mechanistic

89. Ketogenic diet modifies ribosomal protein dysregulation in KMT2D Kabuki syndrome.

Tsang E, Han VX, Flutter C, Alshammery S, Keating BA, Williams T, Gloss BS, Graham ME, Aryamanesh N, Pang I, Wong M, Winlaw D, Cardamone M, Mohammad S, Gold W, Patel S, Dale RC · EBioMedicine · 2024-05-19

Preclinical / mechanistic

90. Ketogenic diet does not promote triple-negative and luminal mammary tumor growth and metastasis in experimental mice.

Grube M, Dimmler A, Schmaus A, Saup R, Wagner T, Garvalov BK, Sleeman JP, Thiele W · Clinical & experimental metastasis · 2023-12-09

Clinical trial / intervention

91. Ketogenic diet induces p53-dependent cellular senescence in multiple organs.

Wei SJ, Schell JR, Chocron ES, Varmazyad M, Xu G, Chen WH, Martinez GM, Dong FF, Sreenivas P, Trevino R, Jiang H, Du Y, Saliba A, Qian W, Lorenzana B, Nazarullah A, Chang J, Sharma K, Munkácsy E, Horikoshi N, Gius D · Science advances · 2024-05-17

Clinical trial / intervention

92. Ketogenic Diet Alters the Epigenetic and Immune Landscape of Prostate Cancer to Overcome Resistance to Immune Checkpoint Blockade Therapy.

Murphy S, Rahmy S, Gan D, Liu G, Zhu Y, Manyak M, Duong L, He J, Schofield JH, Schafer ZT, Li J, Lu X, Lu X · Cancer research · 2023-09-08

Case report / case series

93. Ketogenic metabolic therapy in conjunction with standard treatment for glioblastoma: A case report.

Phillips MCL, Thotathil Z, Dass PH, Ziad F, Moon BG · Oncology letters · 2024-03-26

Preclinical / mechanistic

94. A ketogenic diet rich in fish oil is superior to other fats in preventing NNK-induced lung cancer in A/J mice.

Elisia I, Yeung M, Kowalski S, Shyp T, Tee J, Hollman S, Wong A, King J, Dyer R, Sorensen PH, Krystal G · Scientific reports · 2024-03-07

Review

95. Ketone bodies in cell physiology and cancer.

Giuliani G, Longo VD · American journal of physiology. Cell physiology · 2024-01-08

Preclinical / mechanistic

96. Anti-tumor effects of ketogenic diets and their synergism with other treatments in mice: Bayesian evidence synthesis of 1755 individual mouse survival data.

Klement RJ · Biomedical journal · 2023-05-26

Preclinical / mechanistic

97. In Vitro Simulated Ketogenic Diet Inhibits the Proliferation and Migration of Liver Cancer Cells by Reducing Insulin Production and Down-regulating FOXC2 Expression.

Ma X, Tian F, Li J, Wu Z, Cao L · The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2024-09-30

Preclinical / mechanistic

98. The combined treatment with ketogenic diet and metformin slows tumor growth in two mouse models of triple negative breast cancer.

Schmidt K, Thatcher A, Grobe A, Broussard P, Hicks L, Gu H, Ellies LG, Sears DD, Kalachev L, Kroll E · Translational medicine communications · 2024-06-22

Review

99. Beta-Hydroxybutyrate: A Supplemental Molecule for Various Diseases.

Shahtaghi NR, Soni B, Bakrey H, Bigdelitabar S, Jain SK · Current drug targets · 2024-03-28

Preclinical / mechanistic

100. Hepatic safety profile of pancreatic cancer‑bearing mice fed a ketogenic diet in combination with gemcitabine.

Cortez NE, Lanzi CR, Vahmani P, Matsukuma K, Mackenzie GG · Oncology letters · 2023-09-22

Review

101. The role of intermittent fasting and the ketogenic diet in cancer disease: can they replace the Mediterranean diet?

Küçük AN, Çiftçi S · European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) · 2023-07-03

Other

102. Obesity control and liver health in breast cancer: Normalized hepatic elasticity after ketogenic diet.

Georgiev A, Chervenkov L, Koleva D, Anastasova V · Heliyon · 2023-09-26

Preclinical / mechanistic

103. Ketone Bodies Induce Unique Inhibition of Tumor Cell Proliferation and Enhance the Efficacy of Anti-Cancer Agents.

Miller AI, Diaz D, Lin B, Krzesaj PK, Ustoyev S, Shim A, Fine EJ, Sarafraz-Yazdi E, Pincus MR, Feinman RD · Biomedicines · 2023-09-12

Clinical trial / intervention

104. Ketogenic Diet as a Possible Non-pharmacological Therapy in Main Endocrine Diseases of the Female Reproductive System: A Practical Guide for Nutritionists.

Camajani E, Feraco A, Verde L, Moriconi E, Marchetti M, Colao A, Caprio M, Muscogiuri G, Barrea L · Current obesity reports · 2023-07-05

Other

105. Ketogenic diet in cancer: insufficient stress response?

Starling S · Nature reviews. Endocrinology · 2023-08-11

Review

106. Current knowledges in pharmaconutrition: "Ketogenics" in pediatric gliomas.

Cecchi N, Romanelli R, Ricevuti F, Amitrano M, Carbone MG, Dinardo M, Burgio E · Frontiers in nutrition · 2023-08-08

Preclinical / mechanistic

107. Overcome Prostate Cancer Resistance to Immune Checkpoint Therapy with Ketogenic Diet-Induced Epigenetic Reprogramming.

Murphy S, Rahmy S, Gan D, Zhu Y, Manyak M, Li J, Lu X, Lu X · bioRxiv : the preprint server for biology · 2023-08-08

Preclinical / mechanistic

108. A Ketogenic Diet Induces Tumor Ferroptosis but Accelerates Cachexia.

Cancer discovery · 2023-08-07

Preclinical / mechanistic

109. Raf/MEK/ERK Signaling Pathway Is Involved in the Inhibition of Glioma Cell Proliferation and Invasion in the Ketogenic Microenvironment.

Fan WT, Liu XF, Liang RC · Current medical science · 2023-07-27

Clinical trial / intervention

110. Ketogenic diet promotes tumor ferroptosis but induces relative corticosterone deficiency that accelerates cachexia.

Ferrer M, Mourikis N, Davidson EE, Kleeman SO, Zaccaria M, Habel J, Rubino R, Gao Q, Flint TR, Young L, Connell CM, Lukey MJ, Goncalves MD, White EP, Venkitaraman AR, Janowitz T · Cell metabolism · 2023-06-12

Review

111. Ketogenic diet in cancer management.

Talib WH, Al-Dalaeen A, Mahmod AI · Current opinion in clinical nutrition and metabolic care · 2023-05-09

Clinical trial / intervention

112. A Ketogenic Diet in Combination with Gemcitabine Mitigates Pancreatic Cancer-Associated Cachexia in Male and Female KPC Mice.

Cortez NE, Pathak S, Rodriguez Lanzi C, Hong BV, Crone R, Sule R, Wang F, Chen S, Gomes AV, Baar K, Mackenzie GG · International journal of molecular sciences · 2023-06-28

Preclinical / mechanistic

113. Unrestricted Ketogenic Diet Feeding Enhances Epithelial Ovarian Cancer Growth In Vivo.

AlHilli MM, Rhoades EE, Chau D, Tewari S, Reich A, Myers A, Lindner DJ, Lathia JD, Zhang R, Willard B, Cresci G, Berger NA, Reizes O · Nutrients · 2023-06-13

Preclinical / mechanistic

114. Donkey Oil-Based Ketogenic Diet Prevents Tumor Progression by Regulating Intratumor Inflammation, Metastasis and Angiogenesis in CT26 Tumor-Bearing Mice.

Zhang H, Xie L, Zhang N, Qi X, Lu T, Xing J, Akhtar MF, Li L, Liu G · Genes · 2023-04-30

Clinical trial / intervention

115. Case report: Resolution of malignant canine mast cell tumor using ketogenic metabolic therapy alone.

Seyfried TN, Mukherjee P, Lee DC, Ta L, Nations L · Frontiers in nutrition · 2023-03-28

Review

116. [Is ketogenic diet effective against cancer ?].

Tankeu AT, Barigou M, Pedro R, De Micheli R, Bodmer A, Genton L, Collet TH, Tran C · Revue medicale suisse · 2023-03-23

Clinical trial / intervention

117. Ketogenic therapies for glioblastoma: Understanding the limitations in transitioning from mice to patients.

Clontz AD · Frontiers in nutrition · 2023-03-07

Review

118. The Ketogenic Diet in Colorectal Cancer: A Means to an End.

Tamraz M, Al Ghossaini N, Temraz S · International journal of molecular sciences · 2023-02-12

Systematic review / meta-analysis

119. Effect of Ketogenic Diets on Cardio-Metabolic Outcomes in Cancer Patients: A Systematic Review and Meta-Analysis of Controlled Clinical Trials.

Amanollahi A, Khazdouz M, Malekahmadi M, Klement RJ, Lee D, Khodabakhshi A · Nutrition and cancer · 2022-09-15

Guideline / consensus

120. Methodological Approaches to Ketogenic Dietary Treatments in Glioma Patients from a Nutritional Point of View.

Guo A, Asztely F, Smits A, Jakola AS · Nutrition and cancer · 2022-08-12

Preclinical / mechanistic

121. Correction: A Ketogenic Diet in Combination with Gemcitabine Increases Survival in Pancreatic Cancer KPC Mice.

Cortez NE, Lanzi CR, Hong BV, Xu J, Wang F, Chen S, Ramsey JJ, Pontifex MG, Müller M, Vauzour D, Vahmani P, Hwang CI, Matsukuma K, Mackenzie GG · Cancer research communications · 2022-12-19

Preclinical / mechanistic

122. Anti-Tumor Effect of the Ketogenic Diet against DMH-Induced Colon Cancer in Rats.

Eftekhari P, Jannesar K, Pourjabali M, Rezaei S, Soraya H, Masoudi N · Maedica · 2023-02-23

Randomized clinical trial

123. The Ketogenic Diet: Considerations for Cancer Survivorship.

Miller C, Austin K, Fischer L, Stringer E, Sidhu S · Current nutrition reports · 2022-10-13

Preclinical / mechanistic

124. The ketogenic diet could improve the efficacy of curcumin and Oldenlandia diffusa extract in the treatment of gastric cancer by increasing miR340 expression and apoptosis mediated by autophagy, oxidative stress, and angiogenesis.

Xiao Q, Deng B, Akbari A, Liu Q, Zhu B · Journal of food biochemistry · 2022-10-11

Systematic review / meta-analysis

125. Bibliometric and visual analysis in the field of ketogenic diet on cancer from 2012 to 2021.

Li R, Huang Q, Ye C, Wu C, Luo N, Lu Y, Fang J, Wang Y · Frontiers in nutrition · 2022-11-10

Randomized clinical trial

126. Impact of a ketogenic diet intervention during radiotherapy on body composition: V. Final results of the KETOCOMP study for head and neck cancer patients.

Klement RJ, Sweeney RA · Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2022-05-02

Clinical trial / intervention

127. Metabolism-Based Molecular Subtyping Endows Effective Ketogenic Therapy in p53-Mutant Colon Cancer.

Tang M, Xu H, Huang H, Kuang H, Wang C, Li Q, Zhang X, Ge Y, Song M, Zhang X, Wang Z, Ma C, Kang J, Zhang W, Wang Y, Zhang B, Zhang X, Chen Y, Cong M, Melino G, Wang X, Zhou F, Sun Q, Shi H · Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2022-08-28

Preclinical / mechanistic

128. A ketogenic diet in combination with gemcitabine increases survival in pancreatic cancer KPC mice.

Cortez NE, Rodriguez Lanzi C, Hong BV, Xu J, Wang F, Chen S, Ramsey JJ, Pontifex MG, Müller M, Vauzour D, Vahmani P, Hwang CI, Matsukuma K, Mackenzie GG · Cancer research communications · 2022-09-08

Other

129. Ketogenic diets in healthy dogs induce gut and serum metabolome changes suggestive of anti-tumourigenic effects: A model for human ketotherapy trials.

Allenspach K, Borcherding DC, Iennarella-Servantez CA, Mosichuk AP, Atherly T, Sahoo DK, Kathrani A, Suchodolski JS, Bourgois-Mochel A, Serao MR, Serao NV, Willette A, Perez BA, Gabriel V, Mao S, Kilburn L, Dang V, Borts D, Almada LL, Fernandez-Zapico ME, Phillips GJ, Jergens AE, Mochel JP · Clinical and translational medicine · 2022-08-15

Other

130. Ketogenic Diet as a Chemopreventative and Therapeutic Strategy for Colon Cancer.

Pinato DJ · Gastroenterology · 2022-06-18

Clinical trial / intervention

131. The Effect of Ketogenic Diet on Shared Risk Factors of Cardiovascular Disease and Cancer.

Mohammadifard N, Haghighatdoost F, Rahimlou M, Rodrigues APS, Gaskarei MK, Okhovat P, de Oliveira C, Silveira EA, Sarrafzadegan N · Nutrients · 2022-08-25

Clinical trial / intervention

132. Restricted Ketogenic Diet Therapy for Primary Lung Cancer With Metastasis to the Brain: A Case Report.

Evangeliou AE, Spilioti MG, Vassilakou D, Goutsaridou F, Seyfried TN · Cureus · 2022-08-02

Randomized clinical trial

133. Plant-Based and Ketogenic Diets As Diverging Paths to Address Cancer: A Review.

Shah UA, Iyengar NM · JAMA oncology · 2022-07-08

Preclinical / mechanistic

134. Ketogenic diets slow melanoma growth in vivo regardless of tumor genetics and metabolic plasticity.

Weber DD, Aminzadeh-Gohari S, Thapa M, Redtenbacher AS, Catalano L, Capelôa T, Vazeille T, Emberger M, Felder TK, Feichtinger RG, Koelblinger P, Dallmann G, Sonveaux P, Lang R, Kofler B · Cancer & metabolism · 2022-07-18

Preclinical / mechanistic

135. Long Term Survivals in Aggressive Primary Brain Malignancies Treated With an Adjuvant Ketogenic Diet.

Schwartz KA, Noel M, Nikolai M, Olson LK, Hord NG, Zakem M, Clark J, Elnabtity M, Figueroa B, Chang HT · Frontiers in nutrition · 2022-05-03

Preclinical / mechanistic

136. Ketogenic HMG-CoA lyase and its product β-hydroxybutyrate promote pancreatic cancer progression.

Gouirand V, Gicquel T, Lien EC, Jaune-Pons E, Da Costa Q, Finetti P, Metay E, Duluc C, Mayers JR, Audebert S, Camoin L, Borge L, Rubis M, Leca J, Nigri J, Bertucci F, Dusetti N, Iovanna JL, Tomasini R, Bidaut G, Guillaumond F, Vander Heiden MG, Vasseur S · The EMBO journal · 2022-03-21

Systematic review / meta-analysis

137. Effects of the Ketogenic Diet in the Treatment of Gliomas: A Systematic Review.

Sargaço B, Oliveira PA, Antunes ML, Moreira AC · Nutrients · 2022-02-27

Clinical trial / intervention

138. KETOgenic diet therapy in patients with HEPatocellular adenoma: study protocol of a matched interventional cohort study.

Oudmaijer CAJ, Berk KA, van der Louw EJTM, de Man R, van der Lelij AJ, Hoeijmakers JHJ, IJzermans J · BMJ open · 2022-02-15

Randomized clinical trial

139. Ketogenic diet and chemotherapy combine to disrupt pancreatic cancer metabolism and growth.

Yang L, TeSlaa T, Ng S, Nofal M, Wang L, Lan T, Zeng X, Cowan A, McBride M, Lu W, Davidson S, Liang G, Oh TG, Downes M, Evans R, Von Hoff D, Guo JY, Han H, Rabinowitz JD · Med (New York, N.Y.) · 2022-04-15

Randomized clinical trial

140. Ketogenic diets consumed during radio-chemotherapy have beneficial effects on quality of life and metabolic health in patients with rectal cancer.

Klement RJ, Meyer D, Kanzler S, Sweeney RA · European journal of nutrition · 2021-06-27

Systematic review / meta-analysis

141. The Effect of Ketogenic Diet on Weight Loss in Adult Patients with Cancer: A Systematic Review and Meta-Analysis of Controlled Clinical Trials.

Taftian M, Beigrezaei S, Arabi V, Salehi-Abargouei A · Nutrition and cancer · 2022-02-07

Other

142. Cross Talk between the Ketogenic Diet and Metastatic Prostate Cancer Cells.

Okechukwu CE · The world journal of men's health · 2021-04-15

Review

143. Ketogenic diet: a tool for the management of neuroendocrine neoplasms?

Muscogiuri G, Barrea L, Campolo F, Sbardella E, Sciammarella C, Tarsitano MG, Bottiglieri F, Colao A, Faggiano A, NIKE · Critical reviews in food science and nutrition · 2020-10-14

Review

144. Could ketogenic diet "starve" cancer? Emerging evidence.

Barrea L, Caprio M, Tuccinardi D, Moriconi E, Di Renzo L, Muscogiuri G, Colao A, Savastano S, Obesity Programs of nutrition, Education, Research and Assessment (OPERA) group · Critical reviews in food science and nutrition · 2020-12-04

Review

145. Ketogenic Diets and their Therapeutic Potential on Breast Cancer: A Systemic Review.

Jemal M, Molla TS, Asmamaw Dejenie T · Cancer management and research · 2021-12-14

Clinical trial / intervention

146. Can older patients adopt and maintain a ketogenic diet? An observational study in support of clinical trials in older patients.

Almodallal Y, Cook K, Lammert LM, Lee M, Le-Rademacher JG, Jatoi A · Medicine · 2020-12-15

Clinical trial / intervention

147. Ketogenic diet and cancer: Fad or fabulous?

Mundi MS, Mohamed Elfadil O, Patel I, Patel J, Hurt RT · JPEN. Journal of parenteral and enteral nutrition · 2021-07-06

Clinical trial / intervention

148. Ketogenic Diet for Cancer: Critical Assessment and Research Recommendations.

Lane J, Brown NI, Williams S, Plaisance EP, Fontaine KR · Nutrients · 2021-10-12

Randomized clinical trial

149. Rationale and design of the Diet Restriction and Exercise-induced Adaptations in Metastatic breast cancer (DREAM) study: a 2-arm, parallel-group, phase II, randomized control trial of a short-term, calorie-restricted, and ketogenic diet plus exercise during intravenous chemotherapy versus usual care.

Kirkham AA, King K, Joy AA, Pelletier AB, Mackey JR, Young K, Zhu X, Meza-Junco J, Basi SK, Hiller JP, Brkin T, Michalowski B, Pituskin E, Paterson DI, Courneya KS, Thompson RB, Prado CM · BMC cancer · 2021-10-10

Review

150. Pan-Cancer Analysis of Glycolytic and Ketone Bodies Metabolic Genes: Implications for Response to Ketogenic Dietary Therapy.

Qian L, Li Y, Cao Y, Meng G, Peng J, Li H, Wang Y, Xu T, Zhang L, Sun B, Li B, Yu D · Frontiers in oncology · 2021-10-07

Clinical trial / intervention

151. Effect of high-dose intravenous ascorbic acid on cancer patients following ketogenic diet.

Sebastian S, Paul A, Joby J, Saijan S, Vilapurathu JK · Journal of cancer research and therapeutics · 2021-12-17

Observational human study

152. Ketogenic diet treatment in diffuse intrinsic pontine glioma in children: Retrospective analysis of feasibility, safety, and survival data.

Perez A, van der Louw E, Nathan J, El-Ayadi M, Golay H, Korff C, Ansari M, Catsman-Berrevoets C, von Bueren AO · Cancer reports (Hoboken, N.J.) · 2021-05-03

Clinical trial / intervention

153. Ketogenic Diets in Pancreatic Cancer and Associated Cachexia: Cellular Mechanisms and Clinical Perspectives.

Cortez NE, Mackenzie GG · Nutrients · 2021-09-15

Clinical trial / intervention

154. Feasibility and Biological Activity of a Ketogenic/Intermittent-Fasting Diet in Patients With Glioma.

Schreck KC, Hsu FC, Berrington A, Henry-Barron B, Vizthum D, Blair L, Kossoff EH, Easter L, Whitlow CT, Barker PB, Cervenka MC, Blakeley JO, Strowd RE · Neurology · 2021-07-07

Clinical trial / intervention

155. Ketogenic Diet with Concurrent Chemoradiation in Head and Neck Squamous Cell Carcinoma: Preclinical and Phase 1 Trial Results.

Ma DC, Anderson CM, Rodman SN, Buranasudja V, McCormick ML, Davis A, Loth E, Bodeker KL, Ahmann L, Parkhurst JR, Sun W, Follmer KR, Simons AL, Buatti JM, Spitz DR, Fath MA, Allen BG · Radiation research · 2020-06-23

Clinical trial / intervention

156. A Root in Synapsis and the Other One in the Gut Microbiome-Brain Axis: Are the Two Poles of Ketogenic Diet Enough to Challenge Glioblastoma?

Montella L, Sarno F, Altucci L, Cioffi V, Sigona L, Di Colandrea S, De Simone S, Marinelli A, Facchini BA, De Vita F, Berretta M, de Falco R, Facchini G · Frontiers in nutrition · 2021-07-22

Review

157. A Clinical Perspective of Low Carbohydrate Ketogenic Diets: A Narrative Review.

Sukkar SG, Muscaritoli M · Frontiers in nutrition · 2021-07-12

Review

158. Ketogenic Diet in Cancer Prevention and Therapy: Molecular Targets and Therapeutic Opportunities.

Talib WH, Mahmod AI, Kamal A, Rashid HM, Alashqar AMD, Khater S, Jamal D, Waly M · Current issues in molecular biology · 2021-07-03

Clinical trial / intervention

159. Impact of a ketogenic diet intervention during radiotherapy on body composition: IV. Final results of the KETOCOMP study for rectal cancer patients.

Klement RJ, Koebrunner PS, Meyer D, Kanzler S, Sweeney RA · Clinical nutrition (Edinburgh, Scotland) · 2021-05-31

Preclinical / mechanistic

160. Upregulation of hepatic autophagy under nutritional ketosis.

Liśkiewicz D, Liśkiewicz A, Grabowski M, Nowacka-Chmielewska MM, Jabłońska K, Wojakowska A, Marczak Ł, Barski JJ, Małecki A · The Journal of nutritional biochemistry · 2021-03-08

Systematic review / meta-analysis

161. Cancer Treatment With the Ketogenic Diet: A Systematic Review and Meta-analysis of Animal Studies.

Li J, Zhang H, Dai Z · Frontiers in nutrition · 2021-06-09

Clinical trial / intervention

162. A ketogenic diet consumed during radiotherapy improves several aspects of quality of life and metabolic health in women with breast cancer.

Klement RJ, Weigel MM, Sweeney RA · Clinical nutrition (Edinburgh, Scotland) · 2021-01-27

Clinical trial / intervention

163. Ketogenic Metabolic Therapy, Without Chemo or Radiation, for the Long-Term Management of IDH1-Mutant Glioblastoma: An 80-Month Follow-Up Case Report.

Seyfried TN, Shivane AG, Kalamian M, Maroon JC, Mukherjee P, Zuccoli G · Frontiers in nutrition · 2021-05-31

Systematic review / meta-analysis

164. Efficacy of Low-Carbohydrate Ketogenic Diet as an Adjuvant Cancer Therapy: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

Yang YF, Mattamel PB, Joseph T, Huang J, Chen Q, Akinwunmi BO, Zhang CJP, Ming WK · Nutrients · 2021-04-21

Randomized clinical trial

165. Effects of Ketogenic metabolic therapy on patients with breast cancer: A randomized controlled clinical trial.

Khodabakhshi A, Akbari ME, Mirzaei HR, Seyfried TN, Kalamian M, Davoodi SH · Clinical nutrition (Edinburgh, Scotland) · 2020-07-03

Preclinical / mechanistic

166. The Pros and Cons of Low Carbohydrate and Ketogenic Diets in the Prevention and Treatment of Cancer.

Elisia I, Krystal G · Frontiers in nutrition · 2021-02-25

Clinical trial / intervention

167. Ketogenic diet and ketone bodies enhance the anticancer effects of PD-1 blockade.

Ferrere G, Tidjani Alou M, Liu P, Goubet AG, Fidelle M, Kepp O, Durand S, Iebba V, Fluckiger A, Daillère R, Thelemaque C, Grajeda-Iglesias C, Alves Costa Silva C, Aprahamian F, Lefevre D, Zhao L, Ryffel B, Colomba E, Arnedos M, Drubay D, Rauber C, Raoult D, Asnicar F, Spector T, Segata N, Derosa L, Kroemer G, Zitvogel L · JCI insight · 2021-01-25

Preclinical / mechanistic

168. Metabolic changes and anti-tumor effects of a ketogenic diet combined with anti-angiogenic therapy in a glioblastoma mouse model.

Maeyama M, Tanaka K, Nishihara M, Irino Y, Shinohara M, Nagashima H, Tanaka H, Nakamizo S, Hashiguchi M, Fujita Y, Kohta M, Kohmura E, Sasayama T · Scientific reports · 2021-01-08

Clinical trial / intervention

169. Isocaloric Ketogenic Diet in Adults with High-Grade Gliomas: A Prospective Metabolic Study.

Foppiani A, De Amicis R, Lessa C, Leone A, Ravella S, Ciusani E, Silvani A, Zuccoli G, Battezzati A, Lamperti E, Bertoli S · Nutrition and cancer · 2020-06-17

Other

170. Long-Term Survival Outcomes of Metabolically Supported Chemotherapy with Gemcitabine-Based or FOLFIRINOX Regimen Combined with Ketogenic Diet, Hyperthermia, and Hyperbaric Oxygen Therapy in Metastatic Pancreatic Cancer: A Letter to the Editor.

Ergözen S, Gümüş T · Complementary medicine research · 2021-02-18

Other

171. Effectiveness of Ketogenic Diets on the Survival of Adult Oncological Patients.

Minzer S · Nutrition and cancer · 2020-10-19

Preclinical / mechanistic

172. MR-Spectroscopy and Survival in Mice with High Grade Glioma Undergoing Unrestricted Ketogenic Diet.

Ciusani E, Vasco C, Rizzo A, Girgenti V, Padelli F, Pellegatta S, Fariselli L, Bruzzone MG, Salmaggi A · Nutrition and cancer · 2020-09-21

Randomized clinical trial

173. The Impact of a Ketogenic Dietary Intervention on the Quality of Life of Stage II and III Cancer Patients: A Randomized Controlled Trial in the Caribbean.

Augustus E, Granderson I, Rocke KD · Nutrition and cancer · 2020-08-13

Review

174. [Ketogenic diet – mechanism of action and perspectives for the use in the therapy: data from clinical studies].

Pondel N, Liśkiewicz D, Liśkiewicz A · Postepy biochemii · 2020-12-13

Preclinical / mechanistic

175. The effect of a ketogenic diet and synergy with rapamycin in a mouse model of breast cancer.

Zou Y, Fineberg S, Pearlman A, Feinman RD, Fine EJ · PloS one · 2020-12-03

Randomized clinical trial

176. Maintenance of Energy Homeostasis during Calorically Restricted Ketogenic Diet and Fasting-MR-Spectroscopic Insights from the ERGO2 Trial.

Wenger KJ, Wagner M, Harter PN, Franz K, Bojunga J, Fokas E, Imhoff D, Rödel C, Rieger J, Hattingen E, Steinbach JP, Pilatus U, Voss M · Cancers · 2020-11-27

Randomized clinical trial

177. ERGO2: A Prospective, Randomized Trial of Calorie-Restricted Ketogenic Diet and Fasting in Addition to Reirradiation for Malignant Glioma.

Voss M, Wagner M, von Mettenheim N, Harter PN, Wenger KJ, Franz K, Bojunga J, Vetter M, Gerlach R, Glatzel M, Paulsen F, Hattingen E, Baehr O, Ronellenfitsch MW, Fokas E, Imhoff D, Steinbach JP, Rödel C, Rieger J · International journal of radiation oncology, biology, physics · 2020-06-30

Other

178. Treatment of glioblastoma multiforme with "classic" 4:1 ketogenic diet total meal replacement.

Klein P, Tyrlikova I, Zuccoli G, Tyrlik A, Maroon JC · Cancer & metabolism · 2020-11-09

Observational human study

179. Ketogenic and low-sugar diets for patients with cancer: perceptions and practices of medical oncologists in Canada.

Klassen PN, Goldenberg BA, Lambert P, Vagianos K, Kim CA · Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2020-02-23

Preclinical / mechanistic

180. Ketogenic Diet Elicits Antitumor Properties through Inducing Oxidative Stress, Inhibiting MMP-9 Expression, and Rebalancing M1/M2 Tumor-Associated Macrophage Phenotype in a Mouse Model of Colon Cancer.

Zhang N, Liu C, Jin L, Zhang R, Wang T, Wang Q, Chen J, Yang F, Siebert HC, Zheng X · Journal of agricultural and food chemistry · 2020-08-19

Preclinical / mechanistic

181. Glioblastoma Utilizes Fatty Acids and Ketone Bodies for Growth Allowing Progression during Ketogenic Diet Therapy.

Sperry J, Condro MC, Guo L, Braas D, Vanderveer-Harris N, Kim KKO, Pope WB, Divakaruni AS, Lai A, Christofk H, Castro MG, Lowenstein PR, Le Belle JE, Kornblum HI · iScience · 2020-08-13

Clinical trial / intervention

182. Ketogenic Diet for Malignant Gliomas: a Review.

Thomas JG, Veznedaroglu E · Current nutrition reports · 2020-07-29

Randomized clinical trial

183. [Inhibitory effect of ketogenic diet on neuroblastoma in BALB/c-nu mouse models].

He J, Lü L, Peng J, Li C, Kong X, Zhang J, Peng L · Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2020-09-08

Randomized clinical trial

184. Does a ketogenic diet have beneficial effects on quality of life, physical activity or biomarkers in patients with breast cancer: a randomized controlled clinical trial.

Khodabakhshi A, Seyfried TN, Kalamian M, Beheshti M, Davoodi SH · Nutrition journal · 2020-08-22

Clinical trial / intervention

185. Impact of a ketogenic diet intervention during radiotherapy on body composition: III-final results of the KETOCOMP study for breast cancer patients.

Klement RJ, Champ CE, Kämmerer U, Koebrunner PS, Krage K, Schäfer G, Weigel M, Sweeney RA · Breast cancer research : BCR · 2020-08-20

Other

186. Loss of HMGCS2 Enhances Lipogenesis and Attenuates the Protective Effect of the Ketogenic Diet in Liver Cancer.

Wang YH, Suk FM, Liao YJ · Cancers · 2020-07-04

Randomized clinical trial

187. Does a ketogenic diet as an adjuvant therapy for drug treatment enhance chemotherapy sensitivity and reduce target lesions in patients with locally recurrent or metastatic Her-2-negative breast cancer? Study protocol for a randomized controlled trial.

Wang Y, Jing MX, Jiang L, Jia YF, Ying E, Cao H, Guo XY, Sun T · Trials · 2020-06-05

Clinical trial / intervention

188. Exploring the Feasibility and Effects of a Ketogenic Diet in Patients With CNS Malignancies: A Retrospective Case Series.

Panhans CM, Gresham G, Amaral LJ, Hu J · Frontiers in neuroscience · 2020-05-19

Case report / case series

189. Promising Effect of a New Ketogenic Diet Regimen in Patients with Advanced Cancer.

Hagihara K, Kajimoto K, Osaga S, Nagai N, Shimosegawa E, Nakata H, Saito H, Nakano M, Takeuchi M, Kanki H, Kagitani-Shimono K, Kijima T · Nutrients · 2020-05-19

Other

190. A ketogenic diet exerts beneficial effects on body composition of cancer patients during radiotherapy: An interim analysis of the KETOCOMP study.

Klement RJ, Schäfer G, Sweeney RA · Journal of traditional and complementary medicine · 2019-03-21

Clinical trial / intervention

191. Survival outcomes of metabolically supported chemotherapy combined with ketogenic diet, hyperthermia, and hyperbaric oxygen therapy in advanced gastric cancer.

Iyikesici MS · Nigerian journal of clinical practice · 2020-05-06

Other

192. Addressing the controversial role of ketogenic diets in cancer treatment.

Klement RJ · Expert review of anticancer therapy · 2020-03-29

Review

193. Role of the ketogenic diet in acute neurological diseases.

Arora N, Mehta TR · Clinical neurology and neurosurgery · 2020-02-15

Preclinical / mechanistic

194. The contribution of ketone bodies to glycolytic inhibition for the treatment of adult and pediatric glioblastoma.

Vallejo FA, Shah SS, de Cordoba N, Walters WM, Prince J, Khatib Z, Komotar RJ, Vanni S, Graham RM · Journal of neuro-oncology · 2020-02-24

Preclinical / mechanistic

195. A ketogenic diet combined with melatonin overcomes cisplatin and vincristine drug resistance in breast carcinoma syngraft.

Talib WH · Nutrition (Burbank, Los Angeles County, Calif.) · 2019-11-27

Review

196. Modulation of Cellular Biochemistry, Epigenetics and Metabolomics by Ketone Bodies. Implications of the Ketogenic Diet in the Physiology of the Organism and Pathological States.

Dąbek A, Wojtala M, Pirola L, Balcerczyk A · Nutrients · 2020-03-17

Review

197. Consideration of Ketogenic Metabolic Therapy as a Complementary or Alternative Approach for Managing Breast Cancer.

Seyfried TN, Mukherjee P, Iyikesici MS, Slocum A, Kalamian M, Spinosa JP, Chinopoulos C · Frontiers in nutrition · 2020-03-11

Randomized clinical trial

198. Ketogenic diets as an adjuvant therapy for glioblastoma (KEATING): a randomized, mixed methods, feasibility study.

Martin-McGill KJ, Marson AG, Tudur Smith C, Young B, Mills SJ, Cherry MG, Jenkinson MD · Journal of neuro-oncology · 2020-02-08

Review

199. Ketogenic diets and protective mechanisms in epilepsy, metabolic disorders, cancer, neuronal loss, and muscle and nerve degeneration.

Li RJ, Liu Y, Liu HQ, Li J · Journal of food biochemistry · 2020-01-14

Clinical trial / intervention

200. Ketogenic diet in the treatment of cancer - Where do we stand?

Weber DD, Aminzadeh-Gohari S, Tulipan J, Catalano L, Feichtinger RG, Kofler B · Molecular metabolism · 2019-07-27

Preclinical / mechanistic

201. A ketogenic diet attenuates proliferation and stemness of glioma stem‑like cells by altering metabolism resulting in increased ROS production.

Ji CC, Hu YY, Cheng G, Liang L, Gao B, Ren YP, Liu JT, Cao XL, Zheng MH, Li SZ, Wan F, Han H, Fei Z · International journal of oncology · 2019-12-13

Systematic review / meta-analysis

202. Ketogenic diets in medical oncology: a systematic review with focus on clinical outcomes.

Klement RJ, Brehm N, Sweeney RA · Medical oncology (Northwood, London, England) · 2020-01-11

Other

203. [Ketogenic diet: a new nutritional strategy for cancer therapy?].

Charlot A, Conrad O, Zoll J · Biologie aujourd'hui · 2020-12-24

Randomized clinical trial

204. Diet and Chemotherapy: The Effects of Fasting and Ketogenic Diet on Cancer Treatment.

Plotti F, Terranova C, Luvero D, Bartolone M, Messina G, Feole L, Cianci S, Scaletta G, Marchetti C, Di Donato V, Fagotti A, Scambia G, Benedetti Panici P, Angioli R · Chemotherapy · 2020-11-16

Clinical trial / intervention

205. Long-Term Survival Outcomes of Metabolically Supported Chemotherapy with Gemcitabine-Based or FOLFIRINOX Regimen Combined with Ketogenic Diet, Hyperthermia, and Hyperbaric Oxygen Therapy in Metastatic Pancreatic Cancer.

Iyikesici MS · Complementary medicine research · 2019-09-17

Preclinical / mechanistic

206. Ketogenic diet combined with antioxidant N-acetylcysteine inhibits tumor growth in a mouse model of anaplastic thyroid cancer.

Aggarwal A, Yuan Z, Barletta JA, Lorch JH, Nehs MA · Surgery · 2019-09-12

Randomized clinical trial

207. A Ketogenic Diet Is Acceptable in Women with Ovarian and Endometrial Cancer and Has No Adverse Effects on Blood Lipids: A Randomized, Controlled Trial.

Cohen CW, Fontaine KR, Arend RC, Gower BA · Nutrition and cancer · 2019-07-27

Review

208. Multi-dimensional roles of ketone bodies in cancer biology: Opportunities for cancer therapy.

Feng S, Wang H, Liu J, Aa J, Zhou F, Wang G · Pharmacological research · 2019-10-16

Clinical trial / intervention

209. Postoperative serum metabolites of patients on a low carbohydrate ketogenic diet after pancreatectomy for pancreatobiliary cancer: a nontargeted metabolomics pilot study.

Kang CM, Yun B, Kim M, Song M, Kim YH, Lee SH, Lee H, Lee SM, Lee SM · Scientific reports · 2019-11-14

Other

210. Author response to 'Problems associated with a highly artificial ketogenic diet: Letter to the Editor Re: van der Louw EJTM, Olieman JF, van den Bemt PMLA, et al. "Ketogenic diet treatment as adjuvant to standard treatment of glioblastoma multiforme: a feasibility and safety study"'.

van der Louw EJ, Olieman JF, Catsman-Berrevoets CE, Vincent AJPE · Therapeutic advances in medical oncology · 2019-10-14

Other

211. Problems associated with a highly artificial ketogenic diet: Letter to the Editor Re: van der Louw EJTM, Olieman JF, van den Bemt PMLA, et al. 'Ketogenic diet treatment as adjuvant to standard treatment of glioblastoma multiforme: a feasibility and safety study'.

Klement RJ, Sweeney RA, Gross EC, Champ CE · Therapeutic advances in medical oncology · 2019-10-14

Preclinical / mechanistic

212. Provocative Question: Should Ketogenic Metabolic Therapy Become the Standard of Care for Glioblastoma?

Seyfried TN, Shelton L, Arismendi-Morillo G, Kalamian M, Elsakka A, Maroon J, Mukherjee P · Neurochemical research · 2019-04-25

Systematic review / meta-analysis

213. Treatment of malignant gliomas with ketogenic or caloric restricted diets: A systematic review of preclinical and early clinical studies.

Noorlag L, De Vos FY, Kok A, Broekman MLD, Seute T, Robe PA, Snijders TJ · Clinical nutrition (Edinburgh, Scotland) · 2018-11-14

Preclinical / mechanistic

214. Regulation of Ketogenic Enzyme HMGCS2 by Wnt/β-catenin/PPARγ Pathway in Intestinal Cells.

Kim JT, Li C, Weiss HL, Zhou Y, Liu C, Wang Q, Evers BM · Cells · 2019-09-19

Preclinical / mechanistic

215. Untargeted Metabolomics Reveals Molecular Effects of Ketogenic Diet on Healthy and Tumor Xenograft Mouse Models.

Licha D, Vidali S, Aminzadeh-Gohari S, Alka O, Breitkreuz L, Kohlbacher O, Reischl RJ, Feichtinger RG, Kofler B, Huber CG · International journal of molecular sciences · 2019-08-08

Observational human study

216. Feasibility of a modified Atkins diet in glioma patients during radiation and its effect on radiation sensitization.

Woodhouse C, Ward T, Gaskill-Shipley M, Chaudhary R · Current oncology (Toronto, Ont.) · 2019-08-01

Review

217. Wilhelm Brünings' forgotten contribution to the metabolic treatment of cancer utilizing hypoglycemia and a very low carbohydrate (ketogenic) diet.

Klement RJ · Journal of traditional and complementary medicine · 2018-08-20

Other

218. Editorial: Ketogenic diets and tumour hypoxia - kulturkampf and 'the insurgency'.

Grimble G, Ryall J · Current opinion in clinical nutrition and metabolic care · 2019-06-05

Other

219. Comment on: Ketogenic diet treatment in recurrent diffuse intrinsic pontine glioma in children: A safety and feasibility study.

Perez A, Merlini L, El-Ayadi M, Korff C, Ansari M, von Bueren AO · Pediatric blood & cancer · 2019-02-15

Review

220. Effect of ketogenic diets on leukocyte counts in patients with epilepsy.

Schreck KC, Lwin M, Strowd RE, Henry-Barron BJ, Blakeley JO, Cervenka MC · Nutritional neuroscience · 2017-12-18

Other

221. Ketogenic diet treatment as adjuvant to standard treatment of glioblastoma multiforme: a feasibility and safety study.

van der Louw EJTM, Olieman JF, van den Bemt PMLA, Bromberg JEC, Oomen-de Hoop E, Neuteboom RF, Catsman-Berrevoets CE, Vincent AJPE · Therapeutic advances in medical oncology · 2019-06-21

Clinical trial / intervention

222. Targeting the Warburg effect for cancer treatment: Ketogenic diets for management of glioma.

Poff A, Koutnik AP, Egan KM, Sahebjam S, D'Agostino D, Kumar NB · Seminars in cancer biology · 2017-12-30

Preclinical / mechanistic

223. Therapeutic benefit of combining calorie-restricted ketogenic diet and glutamine targeting in late-stage experimental glioblastoma.

Mukherjee P, Augur ZM, Li M, Hill C, Greenwood B, Domin MA, Kondakci G, Narain NR, Kiebish MA, Bronson RT, Arismendi-Morillo G, Chinopoulos C, Seyfried TN · Communications biology · 2019-05-29

Preclinical / mechanistic

224. A ketogenic diet improves the prognosis in a mouse model of peritoneal dissemination without tumor regression.

Kasumi E, Sato N · Journal of clinical biochemistry and nutrition · 2019-03-07

Preclinical / mechanistic

225. Effects of a Ketogenic Diet on [18F]FDG-PET Imaging in a Mouse Model of Lung Cancer.

Cussó L, Musteanu M, Mulero F, Barbacid M, Desco M · Molecular imaging and biology · 2018-07-04

Review

226. The influence of ketogenic therapy on the 5 R's of radiobiology.

Klement RJ · International journal of radiation biology · 2017-10-09

Clinical trial / intervention

227. The emerging role of ketogenic diets in cancer treatment.

Klement RJ · Current opinion in clinical nutrition and metabolic care · 2018-12-12

Case report / case series

228. Ketogenic diet treatment in recurrent diffuse intrinsic pontine glioma in children: A safety and feasibility study.

van der Louw EJTM, Reddingius RE, Olieman JF, Neuteboom RF, Catsman-Berrevoets CE · Pediatric blood & cancer · 2018-11-28

Observational human study

229. Feasibility study of metabolically supported chemotherapy with weekly carboplatin/paclitaxel combined with ketogenic diet, hyperthermia and hyperbaric oxygen therapy in metastatic non-small cell lung cancer.

Iyikesici MS · International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group · 2019-04-01

Systematic review / meta-analysis

230. A systematic review of the use of ketogenic diets in adult patients with cancer.

Sremanakova J, Sowerbutts AM, Burden S · Journal of human nutrition and dietetics : the official journal of the British Dietetic Association · 2018-07-30

Randomized clinical trial

231. Serial MRI Imaging Reveals Minimal Impact of Ketogenic Diet on Established Liver Tumor Growth.

Byrne FL, Hargett SR, Lahiri S, Roy RJ, Berr SS, Caldwell SH, Hoehn KL · Cancers · 2018-09-05

Randomized clinical trial

232. Favorable Effects of a Ketogenic Diet on Physical Function, Perceived Energy, and Food Cravings in Women with Ovarian or Endometrial Cancer: A Randomized, Controlled Trial.

Cohen CW, Fontaine KR, Arend RC, Soleymani T, Gower BA · Nutrients · 2018-08-30

Preclinical / mechanistic

233. Rescue of 2-Deoxyglucose Side Effects by Ketogenic Diet.

Voss M, Lorenz NI, Luger AL, Steinbach JP, Rieger J, Ronellenfitsch MW · International journal of molecular sciences · 2018-08-20

Clinical trial / intervention

234. Application of Bayesian evidence synthesis to modelling the effect of ketogenic therapy on survival of high grade glioma patients.

Klement RJ, Bandyopadhyay PS, Champ CE, Walach H · Theoretical biology & medical modelling · 2018-08-20

Randomized clinical trial

235. A Ketogenic Diet Reduces Central Obesity and Serum Insulin in Women with Ovarian or Endometrial Cancer.

Cohen CW, Fontaine KR, Arend RC, Alvarez RD, Leath CA, Huh WK, Bevis KS, Kim KH, Straughn JM, Gower BA · The Journal of nutrition · 2017-11-30

Randomized clinical trial

236. The Modified Ketogenic Diet in Adults with Glioblastoma: An Evaluation of Feasibility and Deliverability within the National Health Service.

Martin-McGill KJ, Marson AG, Tudur Smith C, Jenkinson MD · Nutrition and cancer · 2018-04-18

Preclinical / mechanistic

237. Letter to Editor about "Tumor Cells Growth and Survival Time with the Ketogenic Diet in Animal Models: A Systematic Review".

Rezaei S, Abdurahman AA, Mahmoudi M · International journal of preventive medicine · 2018-04-16

Systematic review / meta-analysis

238. The role of ketogenic diets in the therapeutic management of adult and paediatric gliomas: a systematic review.

Martin-McGill KJ, Srikandarajah N, Marson AG, Tudur Smith C, Jenkinson MD · CNS oncology · 2018-04-16

Clinical trial / intervention

239. Low ketolytic enzyme levels in tumors predict ketogenic diet responses in cancer cell lines in vitro and in vivo.

Zhang J, Jia PP, Liu QL, Cong MH, Gao Y, Shi HP, Yu WN, Miao MY · Journal of lipid research · 2018-02-05

Clinical trial / intervention

240. A Nutritional Perspective of Ketogenic Diet in Cancer: A Narrative Review.

Oliveira CLP, Mattingly S, Schirrmacher R, Sawyer MB, Fine EJ, Prado CM · Journal of the Academy of Nutrition and Dietetics · 2017-03-30

Case report / case series

241. Management of Glioblastoma Multiforme in a Patient Treated With Ketogenic Metabolic Therapy and Modified Standard of Care: A 24-Month Follow-Up.

Elsakka AMA, Bary MA, Abdelzaher E, Elnaggar M, Kalamian M, Mukherjee P, Seyfried TN · Frontiers in nutrition · 2018-03-29

Systematic review / meta-analysis

242. [Efficacy of a ketogenic diet in urological cancers patients : A systematic review].

Maisch P, Gschwend JE, Retz M · Der Urologe. Ausg. A · 2018-01-13

Clinical trial / intervention

243. Investigating the Ketogenic Diet As Treatment for Primary Aggressive Brain Cancer: Challenges and Lessons Learned.

Schwartz KA, Noel M, Nikolai M, Chang HT · Frontiers in nutrition · 2018-02-23

Randomized clinical trial

244. A Ketogenic Formula Prevents Tumor Progression and Cancer Cachexia by Attenuating Systemic Inflammation in Colon 26 Tumor-Bearing Mice.

Nakamura K, Tonouchi H, Sasayama A, Ashida K · Nutrients · 2018-02-14

Other

245. Effects of the Ketogenic diet in overweight divers breathing Enriched Air Nitrox.

Bosco G, Rizzato A, Quartesan S, Camporesi E, Mangar D, Paganini M, Cenci L, Malacrida S, Mrakic-Sposta S, Moretti S, Paoli A · Scientific reports · 2018-02-08

Other

246. Efficacy of a ketogenic diet with concomitant intranasal perillyl alcohol as a novel strategy for the therapy of recurrent glioblastoma.

Santos JG, Da Cruz WMS, Schönthal AH, Salazar MD, Fontes CAP, Quirico-Santos T, Da Fonseca CO · Oncology letters · 2017-11-08

Guideline / consensus

247. Ketogenic diets as an adjuvant therapy in glioblastoma (the KEATING trial): study protocol for a randomised pilot study.

Martin-McGill KJ, Marson AG, Tudur Smith C, Jenkinson MD · Pilot and feasibility studies · 2017-11-28

Preclinical / mechanistic

248. A ketogenic diet supplemented with medium-chain triglycerides enhances the anti-tumor and anti-angiogenic efficacy of chemotherapy on neuroblastoma xenografts in a CD1-nu mouse model.

Aminzadeh-Gohari S, Feichtinger RG, Vidali S, Locker F, Rutherford T, O'Donnel M, Stöger-Kleiber A, Mayr JA, Sperl W, Kofler B · Oncotarget · 2017-08-08

Review

249. Rationale, Feasibility and Acceptability of Ketogenic Diet for Cancer Treatment.

Chung HY, Park YK · Journal of cancer prevention · 2017-09-30

Randomized clinical trial

250. The ketogenic diet is not feasible as a therapy in a CD-1 nu/nu mouse model of renal cell carcinoma with features of Stauffer's syndrome.

Vidali S, Aminzadeh-Gohari S, Feichtinger RG, Vatrinet R, Koller A, Locker F, Rutherford T, O'Donnell M, Stöger-Kleiber A, Lambert B, Felder TK, Sperl W, Kofler B · Oncotarget · 2017-07-17

Case report / case series

251. Efficacy of Metabolically Supported Chemotherapy Combined with Ketogenic Diet, Hyperthermia, and Hyperbaric Oxygen Therapy for Stage IV Triple-Negative Breast Cancer.

İyikesici MS, Slocum AK, Slocum A, Berkarda FB, Kalamian M, Seyfried TN · Cureus · 2017-07-07

Randomized clinical trial

252. Consuming a Ketogenic Diet while Receiving Radiation and Chemotherapy for Locally Advanced Lung Cancer and Pancreatic Cancer: The University of Iowa Experience of Two Phase 1 Clinical Trials.

Zahra A, Fath MA, Opat E, Mapuskar KA, Bhatia SK, Ma DC, Rodman SN, Snyders TP, Chenard CA, Eichenberger-Gilmore JM, Bodeker KL, Ahmann L, Smith BJ, Vollstedt SA, Brown HA, Hejleh TA, Clamon GH, Berg DJ, Szweda LI, Spitz DR, Buatti JM, Allen BG · Radiation research · 2017-04-24

Systematic review / meta-analysis

253. Tumor Cells Growth and Survival Time with the Ketogenic Diet in Animal Models: A Systematic Review.

Khodadadi S, Sobhani N, Mirshekar S, Ghiasvand R, Pourmasoumi M, Miraghajani M, Dehsoukhteh SS · International journal of preventive medicine · 2017-05-25

Systematic review / meta-analysis

254. Systematic review: isocaloric ketogenic dietary regimes for cancer patients.

Erickson N, Boscheri A, Linke B, Huebner J · Medical oncology (Northwood, London, England) · 2017-03-28

Other

255. Alternative Ketogenic Diet with Coconut Milk in a Case with Underlying Colorectal Cancer.

Chaiyasit K, Tripipitsiriwat K, Srikaew K, Wiwanitkit V · Indian journal of medical and paediatric oncology : official journal of Indian Society of Medical & Paediatric Oncology · 2017-09-14

Systematic review / meta-analysis

256. Role of ketogenic metabolic therapy in malignant glioma: A systematic review.

Winter SF, Loebel F, Dietrich J · Critical reviews in oncology/hematology · 2017-02-20

Other

257. Changes in cerebral metabolism during ketogenic diet in patients with primary brain tumors: 1H-MRS study.

Artzi M, Liberman G, Vaisman N, Bokstein F, Vitinshtein F, Aizenstein O, Ben Bashat D · Journal of neuro-oncology · 2017-01-10

Other

258. Ketogenic Diets and Cancer: Emerging Evidence.

Tan-Shalaby J · Federal practitioner : for the health care professionals of the VA, DoD, and PHS · 2019-02-16

Clinical trial / intervention

259. Ketogenic Diet and Other Dietary Intervention Strategies in the Treatment of Cancer.

Vergati M, Krasniqi E, Monte GD, Riondino S, Vallone D, Guadagni F, Ferroni P, Roselli M · Current medicinal chemistry · 2016-08-03

Clinical trial / intervention

260. Tumor Metabolism, the Ketogenic Diet and β-Hydroxybutyrate: Novel Approaches to Adjuvant Brain Tumor Therapy.

Woolf EC, Syed N, Scheck AC · Frontiers in molecular neuroscience · 2016-11-16

Other

261. Modified Atkins diet in advanced malignancies - final results of a safety and feasibility trial within the Veterans Affairs Pittsburgh Healthcare System.

Tan-Shalaby JL, Carrick J, Edinger K, Genovese D, Liman AD, Passero VA, Shah RB · Nutrition & metabolism · 2016-08-12

Preclinical / mechanistic

262. A ketogenic diet increases transport and oxidation of ketone bodies in RG2 and 9L gliomas without affecting tumor growth.

De Feyter HM, Behar KL, Rao JU, Madden-Hennessey K, Ip KL, Hyder F, Drewes LR, Geschwind JF, de Graaf RA, Rothman DL · Neuro-oncology · 2016-05-03

Clinical trial / intervention

263. Obesity and tumor growth: inflammation, immunity, and the role of a ketogenic diet.

Wright C, Simone NL · Current opinion in clinical nutrition and metabolic care · 2016-05-12

Preclinical / mechanistic

264. Enhanced immunity in a mouse model of malignant glioma is mediated by a therapeutic ketogenic diet.

Lussier DM, Woolf EC, Johnson JL, Brooks KS, Blattman JN, Scheck AC · BMC cancer · 2016-05-13

Systematic review / meta-analysis

265. Anti-Tumor Effects of Ketogenic Diets in Mice: A Meta-Analysis.

Klement RJ, Champ CE, Otto C, Kämmerer U · PloS one · 2016-05-09

Guideline / consensus

266. Impact of a ketogenic diet intervention during radiotherapy on body composition: I. Initial clinical experience with six prospectively studied patients.

Klement RJ, Sweeney RA · BMC research notes · 2016-03-05

Review

267. Ketogenic diets: from cancer to mitochondrial diseases and beyond.

Branco AF, Ferreira A, Simões RF, Magalhães-Novais S, Zehowski C, Cope E, Silva AM, Pereira D, Sardão VA, Cunha-Oliveira T · European journal of clinical investigation · 2015-11-02

Preclinical / mechanistic

268. Long-term High Fat Ketogenic Diet Promotes Renal Tumor Growth in a Rat Model of Tuberous Sclerosis.

Liśkiewicz AD, Kasprowska D, Wojakowska A, Polański K, Lewin-Kowalik J, Kotulska K, Jędrzejowska-Szypułka H · Scientific reports · 2016-02-19

Review

269. Ketogenic Diet and Cancer-a Perspective.

Smyl C · Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer · 2016-08-26

Case report / case series

270. The development of tumours under a ketogenic diet in association with the novel tumour marker TKTL1: A case series in general practice.

Jansen N, Walach H · Oncology letters · 2015-11-16

Case report / case series

271. Effects of Pre-surgical Vitamin D Supplementation and Ketogenic Diet in a Patient with Recurrent Breast Cancer.

Branca JJ, Pacini S, Ruggiero M · Anticancer research · 2015-09-27

Preclinical / mechanistic

272. FGF21 is not required for glucose homeostasis, ketosis or tumour suppression associated with ketogenic diets in mice.

Stemmer K, Zani F, Habegger KM, Neff C, Kotzbeck P, Bauer M, Yalamanchilli S, Azad A, Lehti M, Martins PJ, Müller TD, Pfluger PT, Seeley RJ · Diabetologia · 2015-06-23

Clinical trial / intervention

273. The Ketogenic Diet Does Not Affect Growth of Hedgehog Pathway Medulloblastoma in Mice.

Dang MT, Wehrli S, Dang CV, Curran T · PloS one · 2015-07-20

Preclinical / mechanistic

274. The Ketogenic Diet Alters the Hypoxic Response and Affects Expression of Proteins Associated with Angiogenesis, Invasive Potential and Vascular Permeability in a Mouse Glioma Model.

Woolf EC, Curley KL, Liu Q, Turner GH, Charlton JA, Preul MC, Scheck AC · PloS one · 2015-06-17

Preclinical / mechanistic

275. Non-Toxic Metabolic Management of Metastatic Cancer in VM Mice: Novel Combination of Ketogenic Diet, Ketone Supplementation, and Hyperbaric Oxygen Therapy.

Poff AM, Ward N, Seyfried TN, Arnold P, D'Agostino DP · PloS one · 2015-06-10

Randomized clinical trial

276. Inhibition of Neuroblastoma Tumor Growth by Ketogenic Diet and/or Calorie Restriction in a CD1-Nu Mouse Model.

Morscher RJ, Aminzadeh-Gohari S, Feichtinger RG, Mayr JA, Lang R, Neureiter D, Sperl W, Kofler B · PloS one · 2015-06-08

Review

277. Mitochondria: The ketogenic diet--A metabolism-based therapy.

Vidali S, Aminzadeh S, Lambert B, Rutherford T, Sperl W, Kofler B, Feichtinger RG · The international journal of biochemistry & cell biology · 2015-02-07

Clinical trial / intervention

278. Treatment of glioma patients with ketogenic diets: report of two cases treated with an IRB-approved energy-restricted ketogenic diet protocol and review of the literature.

Schwartz K, Chang HT, Nikolai M, Pernicone J, Rhee S, Olson K, Kurniali PC, Hord NG, Noel M · Cancer & metabolism · 2015-03-25

Other

279. Response to commentary by Champ and Klement: Is a ketogenic diet the solution for the hyperglycemia problem in glioblastoma therapy?

Mayer A, Vaupel P, Struss HG, Giese A, Stockinger M, Schmidberger H · Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2015-01-18

Review

280. The Efficacy of Ketogenic Diet and Associated Hypoglycemia as an Adjuvant Therapy for High-Grade Gliomas: A Review of the Literature.

Varshneya K, Carico C, Ortega A, Patil CG · Cureus · 2015-02-27

Clinical trial / intervention

281. Growth of human colon cancer cells in nude mice is delayed by ketogenic diet with or without omega-3 fatty acids and medium-chain triglycerides.

Hao GW, Chen YS, He DM, Wang HY, Wu GH, Zhang B · Asian Pacific journal of cancer prevention : APJCP · 2015-03-17

Clinical trial / intervention

282. The ketogenic diet for the treatment of malignant glioma.

Woolf EC, Scheck AC · Journal of lipid research · 2014-02-06

Systematic review / meta-analysis

283. Roles of caloric restriction, ketogenic diet and intermittent fasting during initiation, progression and metastasis of cancer in animal models: a systematic review and meta-analysis.

Lv M, Zhu X, Wang H, Wang F, Guan W · PloS one · 2014-12-11

Preclinical / mechanistic

284. Metabolic reprogramming induced by ketone bodies diminishes pancreatic cancer cachexia.

Shukla SK, Gebregiworgis T, Purohit V, Chaika NV, Gunda V, Radhakrishnan P, Mehla K, Pipinos II, Powers R, Yu F, Singh PK · Cancer & metabolism · 2014-09-01

Clinical trial / intervention

285. Targeting metabolism with a ketogenic diet during the treatment of glioblastoma multiforme.

Champ CE, Palmer JD, Volek JS, Werner-Wasik M, Andrews DW, Evans JJ, Glass J, Kim L, Shi W · Journal of neuro-oncology · 2014-01-19

Review

286. Ketogenic diets as an adjuvant cancer therapy: History and potential mechanism.

Allen BG, Bhatia SK, Anderson CM, Eichenberger-Gilmore JM, Sibenaller ZA, Mapuskar KA, Schoenfeld JD, Buatti JM, Spitz DR, Fath MA · Redox biology · 2014-08-07

Review

287. Restricted calorie ketogenic diet for the treatment of glioblastoma multiforme.

Maroon J, Bost J, Amos A, Zuccoli G · Journal of child neurology · 2013-05-13

Preclinical / mechanistic

288. Ketogenic diets enhance oxidative stress and radio-chemo-therapy responses in lung cancer xenografts.

Allen BG, Bhatia SK, Buatti JM, Brandt KE, Lindholm KE, Button AM, Szweda LI, Smith BJ, Spitz DR, Fath MA · Clinical cancer research : an official journal of the American Association for Cancer Research · 2013-06-06

Clinical trial / intervention

289. Ketolytic and glycolytic enzymatic expression profiles in malignant gliomas: implication for ketogenic diet therapy.

Chang HT, Olson LK, Schwartz KA · Nutrition & metabolism · 2013-07-05

Preclinical / mechanistic

290. The ketogenic diet and hyperbaric oxygen therapy prolong survival in mice with systemic metastatic cancer.

Poff AM, Ari C, Seyfried TN, D'Agostino DP · PloS one · 2013-06-05

Preclinical / mechanistic

291. Brain changes in BDNF and S100B induced by ketogenic diets in Wistar rats.

Vizuete AF, de Souza DF, Guerra MC, Batassini C, Dutra MF, Bernardi C, Costa AP, Gonçalves CA · Life sciences · 2013-04-01

Clinical trial / intervention

292. Calorie or carbohydrate restriction? The ketogenic diet as another option for supportive cancer treatment.

Klement RJ · The oncologist · 2013-09-25

Other

293. Decline of lactate in tumor tissue after ketogenic diet: in vivo microdialysis study in patients with head and neck cancer.

Schroeder U, Himpe B, Pries R, Vonthein R, Nitsch S, Wollenberg B · Nutrition and cancer · 2013-08-06

Review

294. The ketogenic diet for the treatment of glioma: insights from genetic profiling.

Scheck AC, Abdelwahab MG, Fenton KE, Stafford P · Epilepsy research · 2011-10-22

Review

295. Is the restricted ketogenic diet a viable alternative to the standard of care for managing malignant brain cancer?

Seyfried TN, Marsh J, Shelton LM, Huysentruyt LC, Mukherjee P · Epilepsy research · 2011-08-31

Preclinical / mechanistic

296. The ketogenic diet is an effective adjuvant to radiation therapy for the treatment of malignant glioma.

Abdelwahab MG, Fenton KE, Preul MC, Rho JM, Lynch A, Stafford P, Scheck AC · PloS one · 2012-05-01

Preclinical / mechanistic

297. The complete control of glucose level utilizing the composition of ketogenic diet with the gluconeogenesis inhibitor, the anti-diabetic drug metformin, as a potential anti-cancer therapy.

Oleksyszyn J · Medical hypotheses · 2011-05-06

Clinical trial / intervention

298. Effects of a ketogenic diet on the quality of life in 16 patients with advanced cancer: A pilot trial.

Schmidt M, Pfetzer N, Schwab M, Strauss I, Kämmerer U · Nutrition & metabolism · 2011-07-27

Preclinical / mechanistic

299. Differential utilization of ketone bodies by neurons and glioma cell lines: a rationale for ketogenic diet as experimental glioma therapy.

Maurer GD, Brucker DP, Bähr O, Harter PN, Hattingen E, Walenta S, Mueller-Klieser W, Steinbach JP, Rieger J · BMC cancer · 2011-07-26

Preclinical / mechanistic

300. The ketogenic diet reverses gene expression patterns and reduces reactive oxygen species levels when used as an adjuvant therapy for glioma.

Stafford P, Abdelwahab MG, Kim DY, Preul MC, Rho JM, Scheck AC · Nutrition & metabolism · 2010-09-10

Other

301. Metabolic management of glioblastoma multiforme using standard therapy together with a restricted ketogenic diet: Case Report.

Zuccoli G, Marcello N, Pisanello A, Servadei F, Vaccaro S, Mukherjee P, Seyfried TN · Nutrition & metabolism · 2010-04-22

Observational human study

302. Tumor growth in patients with tuberous sclerosis complex on the ketogenic diet.

Chu-Shore CJ, Thiele EA · Brain & development · 2009-05-13

Review

303. Ketosis and the ketogenic diet, 2010: advances in treating epilepsy and other disorders.

Freeman JM, Kossoff EH · Advances in pediatrics · 2010-11-09

Review

304. Targeting energy metabolism in brain cancer through calorie restriction and the ketogenic diet.

Seyfried BT, Kiebish M, Marsh J, Mukherjee P · Journal of cancer research and therapeutics · 2009-12-17

Review

305. Targeting energy metabolism in brain cancer with calorically restricted ketogenic diets.

Seyfried TN, Kiebish M, Mukherjee P, Marsh J · Epilepsia · 2008-12-17

Clinical trial / intervention

306. The ketogenic diet: uses in epilepsy and other neurologic illnesses.

Barañano KW, Hartman AL · Current treatment options in neurology · 2008-11-08

Preclinical / mechanistic

307. Growth of human gastric cancer cells in nude mice is delayed by a ketogenic diet supplemented with omega-3 fatty acids and medium-chain triglycerides.

Otto C, Kaemmerer U, Illert B, Muehling B, Pfetzer N, Wittig R, Voelker HU, Thiede A, Coy JF · BMC cancer · 2008-04-30

Preclinical / mechanistic

308. The calorically restricted ketogenic diet, an effective alternative therapy for malignant brain cancer.

Zhou W, Mukherjee P, Kiebish MA, Markis WT, Mantis JG, Seyfried TN · Nutrition & metabolism · 2007-02-21

Review

309. Is there a role for a low-carbohydrate ketogenic diet in the management of prostate cancer?

Mavropoulos JC, Isaacs WB, Pizzo SV, Freedland SJ · Urology · 2005-12-04

Preclinical / mechanistic

310. Role of glucose and ketone bodies in the metabolic control of experimental brain cancer.

Seyfried TN, Sanderson TM, El-Abbadi MM, McGowan R, Mukherjee P · British journal of cancer · 2003-10-02

Review

311. Implementing a ketogenic diet based on medium-chain triglyceride oil in pediatric patients with cancer.

Nebeling LC, Lerner E · Journal of the American Dietetic Association · 1995-06-01

Case report / case series

312. Effects of a ketogenic diet on tumor metabolism and nutritional status in pediatric oncology patients: two case reports.

Nebeling LC, Miraldi F, Shurin SB, Lerner E · Journal of the American College of Nutrition · 1995-04-01

Preclinical / mechanistic

313. Ketogenic diet impairs NK cell cytotoxic function in colorectal cancer liver metastasis by inducing ferroptosis via suppression of the p62-Keap1-Nrf2 pathway.

Cai R, Meng Y, Ru M, Wang X, Li W, Liu X, Zhuang S, Huang Y, Diao H · Redox biology · 2025-12-10

Clinical trial / intervention

314. Ketogenic diet therapy for high-grade gliomas combined with standard treatment using an angiogenesis inhibitor: An exploratory pilot study on feasibility.

Sasayama T, Tanaka K, Nagashima H, Takahashi M, Yamanishi M, Kuroda M, Tabuchi S, Hagihara K, Yamanishi S, Ikeuchi Y, Fujita Y, Iwahashi H, Hotta S, Matsunaga M, Sanada S, Muragaki Y, Nishihara M · Neuro-oncology advances · 2025-12-22

Preclinical / mechanistic

315. Putative Role of Fatty Acid Metabolic Therapy Using Ketogenic Diet and HIF-1α Inhibition in Hepatocellular Carcinoma: Evidence from an In Vitro Study.

Kimura N, Kitajima Y, Higure K, Matsufuji S, Ikeda S, Furukawa S, Yukimoto K, Tanaka T, Noshiro H · International journal of molecular sciences · 2025-12-05

Case report / case series

316. Postoperative recurrence of pancreatic cancer controlled for 9 months solely by severe carbohydrate restriction: ketogenic diet.

Einama T, Yonamine N, Hatakeyama M, Ogata S, Kobayashi K, Shinada H, Tsunenari T, Takihata Y, Takao M, Ueno H, Kishi Y · Clinical journal of gastroenterology · 2025-09-16

Preclinical / mechanistic

317. Ketogenic diet inhibits glioma progression by promoting gut microbiota-derived butyrate production.

Chen ML, He Y, Dong XH, Liu HF, Yan ZX, Lu XL, Miao QQ, Zhao QN, Zhang H, Luo L, Wang S, Li JY, Xiang DF, Lin Y, Li TR, Zhou XY, Zhou YY, Mao M, Zhang X, Wei H, Shi Y, Liu XD, Ping YF, Bian XW · Cancer cell · 2025-09-25

Clinical trial / intervention

318. Induction of a metabolic switch from glucose to ketone metabolism programs ketogenic diet-induced therapeutic vulnerability in lung cancer.

Wu Z, Wang Z, Ng SQ, Lidster JA, Schwerd-Kleine P, Phua ZJC, Peh KLE, Ho YY, Yuan J, Shathishwaran S, Yeo XH, Zhang Y, Chiu YHJ, Lau LYE, Lim TKH, Takano A, Tan EH, Skanderup AJ, Tergaonkar V, Han W, Ho YS, Tan DSW, Tam WL · Cell metabolism · 2025-10-24

Review

319. Ketogenic diets: Dietary therapeutic potential on breast cancer.

Annunziata G, Caprio M, Frias-Toral E, Colao A, Barrea L · Seminars in cancer biology · 2025-09-05

Clinical trial / intervention

320. Prospects of the therapeutic approaches of ketogenic diet on the clinical outcomes of cancer: A scoping review.

Al-Taie A, Elmasri J · Bulletin du cancer · 2025-09-05

Clinical trial / intervention

321. Ketogenic diet in the management of disease.

Luong T, Svart M, Gormsen LC, Søndergaard E · Current opinion in clinical nutrition and metabolic care · 2025-08-07

Preclinical / mechanistic

322. Biological role of cytochrome P450 family 1 subfamily A member 1 (CYP1A1) in ketogenic diet-induced modulation of lung cancer.

Kang J, Seo DS, Ahmad Y, Park S, Yoo J, Lee J, Baek S, Joo S, Kwon H, Bae HJ, Lee H, Kwon TK, Jang Y · Life sciences · 2025-06-20

Preclinical / mechanistic

323. Dietary lipids, not ketone body metabolites, influence intestinal tumorigenesis in a ketogenic diet.

Shay JES, Chi F, Tzouanas CN, Hoeve JT, Williams KJ, Sever T, Fuentes I, Yilmaz ÖH · bioRxiv : the preprint server for biology · 2025-09-13

Preclinical / mechanistic

324. Investigating the role of ketogenic diet and high-dose vitamin C in modulating doxorubicin toxicity in a murine breast cancer model.

Al-Jada DN, Takruri HR, Talib WH, Hajeer MH, Shahin NA · Biochemical and biophysical research communications · 2025-07-05

Other

325. Is the ketogenic diet still controversial in cancer treatment?

Klement RJ · Expert review of anticancer therapy · 2025-06-20

Preclinical / mechanistic

326. Divergent sex-specific effects on a ketogenic diet: Male, but not female, mice exhibit oxidative stress and cellular senescence.

Wei SJ, Schell J, Qian W, Silguero M, Baseviciene A, Chen WH, Trevino R, Chocron ES, Ogle MM, Varmazyad M, Martinez GM, Cruz D, Lorenzana B, Dong FF, Jiang H, Nazarullah A, Beardsley RA, Sharma K, Chang J, Munkácsy E, Horikoshi N, Gius D · Cell reports · 2025-07-17

Review

327. The anti-tumour role of ketogenic diet based on energy metabolism.

Wu J, Sun X, Luo H, Luo X, Sun S · Clinical nutrition (Edinburgh, Scotland) · 2025-06-13

Randomized clinical trial

328. Ginkgo ketone ester tablets for the treatment of cognitive impairment associated with chemotherapy for breast cancer - a prospective cohort study.

Chen J, Chen L, Jiang K, Wang D, Wu C, Qin Y, Liu S · Frontiers in pharmacology · 2025-07-21

Randomized clinical trial

329. A phase 1 safety and feasibility trial of a ketogenic diet plus standard of care for patients with recently diagnosed glioblastoma.

Amaral LJ, Gresham G, Kim S, Tighiouart M, Nelson TA, Welborn A, Lockshon L, Noorvash B, Rudnick JD, Irwin SA, Freedland SJ, Hu J · Scientific reports · 2025-07-01

Preclinical / mechanistic

330. Ketone Bodies Inhibit Growth of Hepatoblastoma and Rhabdoid Tumor of the Kidney Cells.

Muto-Fujita E, Yamaoka B, Abe N, Fujiwara K, Uehara S · Anticancer research · 2025-04-25

Preclinical / mechanistic

331. Antiproliferative effect of ketogenic diet on hormone independent mammary gland carcinoma via harnessing glucose metabolism: In-vitro and In-vivo investigations.

Yadav S, Neha, Arman M, Kumar A, Sonkar AB, Shrivastava NK, Singh J, Ansari MN, Aldossary SA, Saeedan AS, Kaithwas G · Journal, genetic engineering & biotechnology · 2025-03-23

Case report / case series

332. Clear Cell Renal Cell Carcinoma With Brain Metastases Treated With Complementary Ketogenic Metabolic Therapy: A Case Report.

Acevedo A, Zapata Laguado M · Cureus · 2025-05-28

Preclinical / mechanistic

333. Metabolic flux analysis of glioblastoma neural stem cells reveals distinctive metabolic phenotypes in ketogenic conditions.

Rushin A, Shaikh A, Hardin C, Deleyrolle LP, Merritt ME · Scientific reports · 2025-05-28

Other

334. Corrigendum: Successful application of dietary ketogenic metabolic therapy in patients with glioblastoma: a clinical study.

Kiryttopoulos A, Evangeliou AE, Katsanika I, Boukovinas I, Foroglou N, Zountsas B, Cheva A, Nikolopoulos V, Zaramboukas T, Duraj T, Seyfried TN, Spilioti M · Frontiers in nutrition · 2025-05-19

Preclinical / mechanistic

335. Nutritional ketosis modulates the methylation of cancer-related genes in patients with obesity and in breast cancer cells.

Lorenzo PM, Izquierdo AG, Rodriguez-Carnero G, Costa-Fraga N, Díaz-Lagares A, Porca C, de Luis D, Tejera C, De Paz L, Cueva J, Bellido D, Crujeiras AB · Journal of physiology and biochemistry · 2025-03-27

Preclinical / mechanistic

336. Integrative insights into the role of CAV1 in ketogenic diet and ferroptosis in pancreatic cancer.

Liang X, Tian R, Li T, Wang H, Qin Y, Qian M, Fan J, Wang D, Cui HY, Jiang J · Cell death discovery · 2025-04-04

Review

337. Ketogenic diet and cancer: multidimensional exploration and research.

Wan S, Zhou X, Xie F, Zhou F, Zhang L · Science China. Life sciences · 2025-01-14

Clinical trial / intervention

338. Ketogenic diet suppresses colorectal cancer through the gut microbiome long chain fatty acid stearate.

Tsenkova M, Brauer M, Pozdeev VI, Kasakin M, Busi SB, Schmoetten M, Cheung D, Meyers M, Rodriguez F, Gaigneaux A, Koncina E, Gilson C, Schlicker L, Herebian D, Schmitz M, de Nies L, Mayatepek E, Haan S, de Beaufort C, Cramer T, Meiser J, Linster CL, Wilmes P, Letellier E · Nature communications · 2025-02-20

Review

339. Correction to: Critical Review of Ketogenic Diet Throughout the Cancer Continuum for Neuroglioma: Insights from a Medical Nutrition Therapy (MNT) Perspective.

Thomopoulos-Titomihelakis KD, Sachs H, McCann R, Zhang Q, Kurnit S, Codoni De Juan G, Rushing A · Current nutrition reports · 2025-02-13

Preclinical / mechanistic

340. Ketogenic diet induces an inflammatory reactive astrocytes phenotype reducing glioma growth.

Rosito M, Maqbool J, Reccagni A, Mangano M, D'Andrea T, Rinaldi A, Peruzzi G, Silvestri B, Rosa A, Trettel F, D'Alessandro G, Catalano M, Fucile S, Limatola C · Cellular and molecular life sciences : CMLS · 2025-02-08

Other

341. Exploring the potential of gemcitabine-metal-organic frameworks in combating pancreatic cancer under ketogenic conditions.

Nekoufar S, Ghorbani M, Safaei S, Khosroushahi GA, Shirian FI, Baradaran B, Tavakoli-Yaraki M · BMC cancer · 2025-01-09

Clinical trial / intervention

342. Comment on "Impact of Intermittent Fasting with a Ketogenic Diet on AMPK Levels in Breast Cancer Patients Receiving Chemotherapy".

Xu Q, Chen X · Nutrition and cancer · 2025-07-02

Clinical trial / intervention

343. Impact of Intermittent Fasting with a Ketogenic Diet on AMPK Levels in Breast Cancer Patients Receiving Chemotherapy.

Lughmani ARK, Ibrahim N, Ali W, Bibi Y, Afzal A, Javed M, Hameed A, Shahzadi W, Saddique S, Ahmed M · Nutrition and cancer · 2025-04-08

Cardiovascular

Cardiovascular Health Recent peer-reviewed literature

Evidence is ordered preferentially by systematic reviews/meta-analyses and recent high-level evidence, followed by recent clinical studies and then relevant mechanistic work.

Systematic review & meta-analysis

1. Impact of very low carbohydrate ketogenic diets on cardiovascular risk factors among patients with type 2 diabetes: GRADE-assessed systematic review and meta-analysis of clinical trials

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Recent review · 2026

2. Ketogenic diet, cardiometabolic diseases and aging

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Long-term human study · 2025

3. Coronary artery calcification in type 1 diabetes after 10-year ketogenic diet

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Recent cardiovascular review · 2025

4. Salutary Effects of Nutritional Ketosis for the Diseased Human Heart

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Human clinical study

5. LDL Keto Trial

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Review / hypothesis

6. The ketogenic diet has the potential to decrease atherosclerotic cardiovascular disease risk

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Human metabolic study · 2024

7. A ketogenic diet lowers myocardial fatty acid oxidation but does not affect oxygen consumption

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Review

8. The Ketogenic Diet and Cardiovascular Diseases

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Translational / clinical cardiovascular study

9. Ketone bodies in right ventricular failure

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Review

10. Ketone bodies in Right Ventricular Failure: A Unique Therapeutic Opportunity

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Mechanistic review

11. Ketone Bodies as Metabolites and Signalling Molecules at the Crossroad between Inflammation and Epigenetic Control of Cardiometabolic Disorders

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Cardiovascular review

12. Ketone bodies and the heart

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Mechanistic review

13. Ketone Body Metabolism in the Ischemic Heart

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Mechanistic review

14. Ketogenic Diet and Cardiac Substrate Metabolism

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Human VLCKD study

15. Heart Rate Variability and Sympathetic Activity Is Modulated by Very Low-Calorie Ketogenic Diet

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Human / clinical or translational evidence

16. Coronary Artery Calcification in Type 1 Diabetes after Ten Years of Ketogenic Nutrition

Original publication title: Coronary Artery Calcification in Type 1 Diabetes after Ten Years of Ketogenic Nutrition

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Human / clinical or translational evidence

17. Ketone Catabolism Is Essential for Maintaining Normal Heart Function During Aging

Original publication title: Ketone Catabolism Is Essential for Maintaining Normal Heart Function During Aging

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Human / clinical or translational evidence

18. Ketogenic Diet and the Potential to Decrease Atherosclerotic Cardiovascular Disease Risk

Original publication title: Ketogenic Diet and the Potential to Decrease Atherosclerotic Cardiovascular Disease Risk

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Systematic review & meta-analysis

19. Impact of Very Low Carbohydrate Ketogenic Diets on Cardiovascular Risk Factors among Patients with Type 2 Diabetes: A GRADE-Assessed Systematic Review and Meta-Analysis

Original publication title: Impact of Very Low Carbohydrate Ketogenic Diets on Cardiovascular Risk Factors among Patients with Type 2 Diabetes: A GRADE-Assessed Systematic Review and Meta-Analysis

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Human / clinical or translational evidence

20. Ketogenic Diet: Mental Health Benefits versus Cardiovascular Risk

Original publication title: Ketogenic Diet: Mental Health Benefits versus Cardiovascular Risk

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Human / clinical or translational evidence

21. Ketogenic Diet and Myocardial Fatty Acid Oxidation in Humans

Original publication title: Ketogenic Diet and Myocardial Fatty Acid Oxidation in Humans

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Human / clinical or translational evidence

22. Ketogenic Diet Inhibits Neointimal Hyperplasia by Suppressing Oxidative Stress and Inflammation

Original publication title: Ketogenic Diet Inhibits Neointimal Hyperplasia by Suppressing Oxidative Stress and Inflammation

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Human / clinical or translational evidence

23. Ketone Bodies and Cardiometabolic Inflammation: Epigenetic Mechanisms

Original publication title: Ketone Bodies and Cardiometabolic Inflammation: Epigenetic Mechanisms

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Human / clinical or translational evidence

24. Ketone Bodies in Ischemic Heart Disease

Original publication title: Ketone Bodies in Ischemic Heart Disease

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Human / clinical or translational evidence

25. Heart Rate Variability during a Very Low-Calorie Ketogenic Diet

Original publication title: Heart Rate Variability during a Very Low-Calorie Ketogenic Diet

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Randomized clinical trial

26. The Ketogenic Diet in the Prevention and Treatment of Hypertension (HTN).

Rodzeń Ł, Dyńka D, Rodzeń M, Karakuła-Juchnowicz H, Łojko D, Kraszewski S, Grzywacz Ż, Bikman B, Unwin J, Unwin D, Fazio S · Biomedicines · 2026-07-31

Preclinical / mechanistic

27. Effect of long-term use of very low-carbohydrate Ketogenic diet on the thyroid gland and adipose tissue of adult male albino rats (biochemical and histological study).

Ibrahim RA, Elwaddah NM, Aziz NM, Yousef JE, Abd El-Aleem SAE, Saber EA · Journal of molecular histology · 2026-07-30

Preclinical / mechanistic

28. Ckmm-Cre transgenic mice maintain phenotypic and cardiac mitochondrial homeostasis during ketogenic feeding.

Dogan SA · Molecular and cellular biochemistry · 2026-07-29

Systematic review / meta-analysis

29. Dietary Interventions and Testosterone Levels in Obese Men: A Systematic Review Comparing the Mediterranean Diet, Ketogenic Diet, and Intermittent Fasting.

La Vignera S, Condorelli RA · Nutrients · 2026-07-24

Randomized clinical trial

30. Acute 1,3-Butanediol Co-Ingestion with Carbohydrate Does Not Improve Endurance Performance in Chronically Ketogenic Male Athletes.

Carpenter M, Brouner J, Spendiff O · Nutrients · 2026-07-22

Systematic review / meta-analysis

31. Ketogenic diet in adult obesity: safety, limitations, and evidence from various clinical applications.

Kacprzak U, Adamaszek N, Buczkowska A, Sochowska J, Flejszman M, Danieluk J, Wójcik J, Stochaj L, Gliński M, Dołęga-Mostowska D · Roczniki Panstwowego Zakladu Higieny · 2026-07-14

Observational human study

32. Ketogenic diet enhances cardiac autonomic stability in pediatric drug-resistant epilepsy: A longitudinal heart rate variability study.

Karaca NB, Kavgacı A, Terlemez S, Aktaş E, Serdaroğlu E, Hirfanoğlu T, Serdaroğlu A, Demir E, Arhan E · Epilepsy research · 2026-07-10

Systematic review / meta-analysis

33. Ketogenic diets and cardiovascular health balancing metabolic benefits against lipid-related risk.

Liu H, Wu W, He N, Wang X, Pan S, Zhu L, Ma S, Zhang Y, Liu Z · BMC cardiovascular disorders · 2026-07-07

Randomized clinical trial

34. Exogenous Ketones Preserve Rate of Force Development in Young Adults.

Stoner JT, Buga A, Crabtree CD, Robinson BT, Decker DD, Sapper TN, Kackley ML, Kraemer WJ, Volek JS · Journal of strength and conditioning research · 2026-06-15

Clinical trial / intervention

35. Serum Uric Acid as a Cardiovascular Risk Marker: Differential Effects of Ketogenic Diet and Intermittent Fasting in Postmenopausal Women.

Pala B, Pennazzi L, Piscione M, Nardoianni G, Miletti G, De Mitri S, Gualtieri P, Di Renzo L, Barbato E, Tocci G · Nutrients · 2026-06-12

Systematic review / meta-analysis

36. Effect of ketone supplementation, a low-carbohydrate diet and a ketogenic diet on heart failure measures and outcomes: a systematic review and meta-analysis.

Liao LP, Church LA, Melville H, Jayasinghe T, Choy C, Zeng A, Barrett N, Marschner S, Gan GCH, Thomas L, Zaman S · Heart (British Cardiac Society) · 2026-06-11

Randomized clinical trial

37. Determinants of Adherence to a Ketogenic Diet in Patients with Heart Failure with Reduced Ejection Fraction.

Liao LP, Murphy B, Gan GCH, Thomas L, Fontana L, McKinn S, Zaman S · Nutrients · 2026-06-09

Other

38. Saturated and Unsaturated Fat-Based Ketogenic Diets Attenuate Atherosclerosis Despite Divergent Effects on Adiposity.

Li X, Abdualkader AM, Lacroix E, Bai C, Pourfarziani P, Martel C, Al Batran R · Arteriosclerosis, thrombosis, and vascular biology · 2026-05-07

Clinical trial / intervention

39. Ketogenic diet enhances cognitive-behavioral function and hippocampal neurogenesis while attenuating amyloid pathology in Tg-SwDI mice.

Pulido-Correa VE, Hernandez AV, Wind EJ, Zhu Y, Vogel C, Binu S, Jeneske M, Kuni D, Chiduruppa V, Echeverria B, Rosenberg L, Robison LS · Journal of Alzheimer's disease : JAD · 2026-05-04

Preclinical / mechanistic

40. Ketone Ester Attenuates Thoracic Aortic Aneurysm and Dissection by Suppressing Ferroptosis.

Shrestha S, Wu Y, Li J, Du X, Song P · Cells · 2026-05-01

Systematic review / meta-analysis

41. Ketogenic diet-induced changes in adult lipid metabolism: a comprehensive systematic review and meta-regression of randomized controlled trials.

Zhao J, Wei C, Gong F, Pang Z, Zhao H · BMC cardiovascular disorders · 2026-04-30

Clinical trial / intervention

42. Ketogenic Diets and Low-Density Lipoprotein Cholesterol in Adults With Normal Weight: An Emerging Clinical Challenge.

DiMattia ZS, Petersen KS · Journal of the American Heart Association · 2026-04-28

Clinical trial / intervention

43. Ketogenic Diet and Brain Health: Cerebrovascular Mechanisms, Neuroprotection, and Translational Implications.

Mózes N, Fehér Á, Csípő T, Fazekas-Pongor V, Lipécz Á, Major D, Lehoczki A, Dósa N, Pártos K, Csík B, Yi HW, Kaposvári C, Horváth K, Fekete M · Nutrients · 2026-03-29

Systematic review / meta-analysis

44. Exploring Non-pharmacological Hypertension Management: DASH, Paleolithic, and Ketogenic Diet Comparisons: A Systematic Review.

Wal P, Rath D, Verma N, Wal A, Bhukta P, Natania A, Ved A, Samathoti P, Gasmi A · Current hypertension reviews · 2026-03-26

Observational human study

45. Corrigendum to "Very-low calorie ketogenic diet reduces central blood pressure and metabolic risk in post-menopausal women with essential hypertension and obesity: a single center, prospective, open-label clinical study" [Nutr Metab Cardiovasc (2025) 4 35 4 103838].

Pala B, Pennazzi L, Nardoianni G, Rubattu SD, Volpe M, Colao AM, Barbato E, Tocci G · Nutrition, metabolism, and cardiovascular diseases : NMCD · 2026-03-18

Other

46. Correction: Ketogenic diet improves disease activity and cardiovascular risk in psoriatic arthritis: A proof of concept study.

Ramonda R, Ometto F, Striani G, Cozzi G, Basso D, Evangelista F, Lorenzin M, Scagnellato L, Aita A, Favero M, Brocadello F, Doria A · PloS one · 2026-03-06

Systematic review / meta-analysis

47. The Impact of the Ketogenic Diet on the Lipid Profile in Adults: A Comprehensive Review and Meta-Regression Analysis of Randomized Controlled Trials.

Chang C, Liu Y, Rohani P, Khodadadi N, Prabahar K, Sohouli MH · Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists · 2026-01-30

Other

48. Hemodynamic Effects of Oral Ketone Ester in Acutely Decompensated Heart Failure With Low Cardiac Output Syndrome.

Sramko M, Wohlfahrt P, Kissimon F, Svirlochova V, Franekova J, Kautzner J, Melenovsky V · JACC. Heart failure · 2026-01-07

Clinical trial / intervention

49. The ketogenic diet is not for everyone: contraindications, side effects, and drug interactions.

Dyńka D, Rodzeń Ł, Rodzeń M, Łojko D, Karakuła-Juchnowicz H, Ede G, Grzywacz Ż, Antosik K, Sethi S, Unwin D · Annals of medicine · 2026-01-04

Guideline / consensus

50. Low-Carbohydrate/Ketogenic Diet and Coronary Artery Disease: A Brief Review of the Limited Evidence Between Them.

Kusayev J, Weininger D, Frishman WH, Aronow WS · Cardiology in review · 2024-02-01

Observational human study

51. Very low-calorie ketogenic diet reduces central blood pressure and cardiometabolic risk in post-menopausal women with essential hypertension and obesity: a single-center, prospective, open-label, clinical study.

Pala B, Pennazzi L, Nardoianni G, Rubattu SD, Volpe M, Colao AM, Barbato E, Tocci G · Nutrition, metabolism, and cardiovascular diseases : NMCD · 2024-12-20

Other

52. Neurohormonal and Renal Effects of 14-Day Oral Ketone Ester Treatment in Patients With Heart Failure With Reduced Ejection Fraction.

Berg-Hansen K, Gopalasingam N, Christensen KH, Svart M, Rittig N, Nielsen R, Lodberg K, Møller N, Wiggers H · Circulation. Heart failure · 2024-12-24

Review

53. The Cardioprotective Effects of Nutritional Ketosis: Mechanisms and Clinical Implications.

Venturini C, Mancinelli L, Matacchione G, Olivieri F, Antonicelli R · Nutrients · 2024-12-05

Systematic review / meta-analysis

54. Exogenous Ketones in Cardiovascular Disease and Diabetes: From Bench to Bedside.

Kansakar U, Nieves Garcia C, Santulli G, Gambardella J, Mone P, Jankauskas SS, Lombardi A · Journal of clinical medicine · 2024-12-04

Systematic review / meta-analysis

55. Impact of ketogenic diet on cardiovascular disease.

Zaghloul MS, Elizondo-Benedetto S, Zayed MA · Nutrition reviews · 2024-11-13

Randomized clinical trial

56. Randomized Crossover Trial of 2-Week Ketone Ester Treatment in Patients With Type 2 Diabetes and Heart Failure With Preserved Ejection Fraction.

Gopalasingam N, Berg-Hansen K, Christensen KH, Ladefoged BT, Poulsen SH, Andersen MJ, Borlaug BA, Nielsen R, Møller N, Wiggers H · Circulation · 2024-08-20

Other

57. The ketogenic diet has the potential to decrease all-cause mortality without a concomitant increase in cardiovascular-related mortality.

Qu X, Huang L, Rong J · Scientific reports · 2024-10-01

Case report / case series

58. The Ketogenic Diet and Pediatric Cardiac Surgery: A Case Report and Narrative Review.

Longacre M, Ohia L, Boyle S, Conner K, Kaza A, Schure A · Journal of cardiothoracic and vascular anesthesia · 2024-04-25

Randomized clinical trial

59. Therapeutic potential of the ketogenic diet: A metabolic switch with implications for neurological disorders, the gut-brain axis, and cardiovascular diseases.

Shahpasand S, Khatami SH, Ehtiati S, Alehossein P, Salmani F, Toutounchi AH, Zarei T, Shahmohammadi MR, Khodarahmi R, Aghamollaii V, Tafakhori A, Karima S · The Journal of nutritional biochemistry · 2024-06-14

Preclinical / mechanistic

60. Ketone Body Metabolism is Not Required for Improvement of Heart Failure by Ketogenic Diet in Mice.

Foulks Z, Weinheimer CJ, Kovacs A, Michael J, Pyles KD, Menezes TN, Cho K, Patti GJ, McCommis KS · bioRxiv : the preprint server for biology · 2024-09-02

Other

61. The ketogenic diet is unable to improve cardiac function in ischaemic heart failure: an unexpected result?

Greco CM, Nisoli E · Cardiovascular research · 2024-09-02

Preclinical / mechanistic

62. The ketogenic diet does not improve cardiac function and blunts glucose oxidation in ischaemic heart failure.

Ho KL, Karwi QG, Wang F, Wagg C, Zhang L, Panidarapu S, Chen B, Pherwani S, Greenwell AA, Oudit GY, Ussher JR, Lopaschuk GD · Cardiovascular research · 2023-12-06

Preclinical / mechanistic

63. Sex- and Age-Specific Differences in Mice Fed a Ketogenic Diet.

Sprankle KW, Knappenberger MA, Locke EJ, Thompson JH, Vinovrski MF, Knapsack K, Kolwicz SC · Nutrients · 2024-08-16

Other

64. Comparative mathematical modeling reveals the differential effects of high-fat diet and ketogenic diet on the PI3K-Akt signaling pathway in heart.

Tseng YY · Nutrition & metabolism · 2024-08-09

Systematic review / meta-analysis

65. Impact of the ketogenic diet as a dietary approach on cardiovascular disease risk factors: a meta-analysis of randomized clinical trials.

Wang Z, Chen T, Wu S, Dong X, Zhang M, Ma G · The American journal of clinical nutrition · 2024-07-15

Other

66. Advanced cardiovascular physiology in an individual with type 1 diabetes after 10-year ketogenic diet.

Watso JC, Robinson AT, Singar SAB, Cuba JN, Koutnik AP · American journal of physiology. Cell physiology · 2024-06-24

Other

67. Standardized ketogenic dietary preparation for metabolic PET imaging in suspected and known cardiac sarcoidosis.

Hutt E, Goldar G, Jaber WA, Cremer PC · European heart journal. Imaging methods and practice · 2024-05-09

Randomized clinical trial

68. Cardiovascular Effects of Oral Ketone Ester Treatment in Patients With Heart Failure With Reduced Ejection Fraction: A Randomized, Controlled, Double-Blind Trial.

Berg-Hansen K, Gopalasingam N, Christensen KH, Ladefoged B, Andersen MJ, Poulsen SH, Borlaug BA, Nielsen R, Møller N, Wiggers H · Circulation · 2024-03-27

Review

69. Ketone Bodies after Cardiac Arrest: A Narrative Review and the Rationale for Use.

Annoni F, Gouvea Bogossian E, Peluso L, Su F, Moreau A, Nobile L, Casu SG, Sterchele ED, Calabro L, Salvagno M, Oddo M, Taccone FS · Cells · 2024-05-04

Other

70. Opinion: Are mental health benefits of the ketogenic diet accompanied by an increased risk of cardiovascular disease?

Diamond DM, Mason P, Bikman BT · Frontiers in nutrition · 2024-05-01

Clinical trial / intervention

71. Dietary Influence on Drug Efficacy: A Comprehensive Review of Ketogenic Diet-Pharmacotherapy Interactions.

Marinescu SCN, Apetroaei MM, Nedea MII, Arsene AL, Velescu BȘ, Hîncu S, Stancu E, Pop AL, Drăgănescu D, Udeanu DI · Nutrients · 2024-04-19

Other

72. The Significant Impact of High-Fat, Low-Carbohydrate Ketogenic Diet on Serum Lipid Profile and Atherosclerotic Cardiovascular Disease Risk in Overweight and Obese Adults.

Khdher S, Mohammed S, Muhammed K, Ismael A · Cureus · 2024-04-09

Systematic review / meta-analysis

73. Effect of ketogenic diet on blood pressure: A GRADE-Assessed systematic review and meta-analysis of randomized controlled trials.

Amini MR, Askarpour M, Ghalandari H, Gholizadeh M, Pouraram H · Nutrition, metabolism, and cardiovascular diseases : NMCD · 2023-12-12

Review

74. Effect of Ketogenic Diet on Obesity and Other Metabolic Disorders: Narrative Review.

Baylie T, Ayelgn T, Tiruneh M, Tesfa KH · Diabetes, metabolic syndrome and obesity : targets and therapy · 2024-03-21

Randomized clinical trial

75. A ketogenic diet lowers myocardial fatty acid oxidation but does not affect oxygen consumption: a study in overweight humans.

Luong TV, Pedersen MGB, Abild CB, Cunnane SC, Croteau E, Lauritsen KM, Kjaerulff MLG, Tolbod LP, Møller N, Søndergaard E, Gormsen LC · Obesity (Silver Spring, Md.) · 2024-01-23

Review

76. Ketogenic diet and cardiovascular risk - state of the art review.

Popiolek-Kalisz J · Current problems in cardiology · 2024-01-15

Review

77. Understanding the Relationship between the Ketogenic Diet and the Heart: A Novel Therapeutic Potential for Cardiovascular Health.

Shah P, Sawhney A, Anamika F, Kanagala SG, Parikh K, Mendpara V, Garg N, Jain R · Cardiovascular & hematological agents in medicinal chemistry · 2023-06-15

Review

78. Beta-Hydroxybutyrate: A Supplemental Molecule for Various Diseases.

Shahtaghi NR, Soni B, Bakrey H, Bigdelitabar S, Jain SK · Current drug targets · 2024-03-28

Systematic review / meta-analysis

79. Effect of Acute and Chronic Ingestion of Exogenous Ketone Supplements on Blood Pressure: A Systematic Review and Meta-Analysis.

Marcotte-Chénard A, Tremblay R, Falkenhain K, Little JP, Riesco E · Journal of dietary supplements · 2023-12-25

Preclinical / mechanistic

80. Ketogenic Diet Regulates Cardiac Remodeling and Calcium Homeostasis in Diabetic Rat Cardiomyopathy.

Lee TI, Trang NN, Lee TW, Higa S, Kao YH, Chen YC, Chen YJ · International journal of molecular sciences · 2023-11-09

Clinical trial / intervention

81. Nutritional Intervention in Cushing's Disease: The Ketogenic Diet's Effects on Metabolic Comorbidities and Adrenal Steroids.

Guarnotta V, Amodei R, Di Gaudio F, Giordano C · Nutrients · 2023-11-02

Other

82. Reply to Najjar, R.S. Comment on "Dyńka et al. The Ketogenic Diet and Cardiovascular Diseases. Nutrients 2023, 15, 3368".

Dyńka D, Kowalcze K, Charuta A, Paziewska A · Nutrients · 2023-10-10

Other

83. Jump Starting the Heart: Ketone Esters Improve Cardiac Function in Patients With Cardiogenic Shock.

Lopaschuk GD, Karwi QG · JACC. Heart failure · 2023-07-12

Randomized clinical trial

84. Beneficial Effects of Ketone Ester in Patients With Cardiogenic Shock: A Randomized, Controlled, Double-Blind Trial.

Berg-Hansen K, Christensen KH, Gopalasingam N, Nielsen R, Eiskjær H, Møller N, Birkelund T, Christensen S, Wiggers H · JACC. Heart failure · 2023-07-12

Randomized clinical trial

85. Short- and long-term effects of very low- and low-calorie ketogenic diets on metabolism and cardiometabolic risk factors: a narrative review.

Gaspa G, Naciu AM, DI Rosa C, Lattanzi G, Beato I, Micheli V, Turriziani C, Khazrai YM, Cesareo R · Minerva endocrinology · 2022-10-26

Preclinical / mechanistic

86. Ketone ester supplementation suppresses cardiac inflammation and improves cardiac energetics in a swine model of acute myocardial infarction.

Yurista SR, Eder RA, Welsh A, Jiang W, Chen S, Foster AN, Mauskapf A, Tang WHW, Hucker WJ, Coll-Font J, Rosenzweig A, Nguyen CT · Metabolism: clinical and experimental · 2023-06-01

Review

87. [Potential implications of ketone body metabolism changes and ketogenic therapy in the treatment of heart failure].

Wang Q, Yan S, Kuang S, Zhou M, Jiang C · Zhonghua wei zhong bing ji jiu yi xue · 2023-08-08

Other

88. Ketogenic Diet in Heart Failure: Fact or Fiction?

Kodur N, Yurista S, Province V, Rueth E, Nguyen C, Tang WHW · JACC. Heart failure · 2022-09-30

Randomized clinical trial

89. Effects of Hypocaloric Low-Fat, Ketogenic, and Ketogenic and Ketone Supplement Diets on Aldosterone and Renin.

Belany P, Kackley ML, Zhao S, Kluwe B, Buga A, Crabtree CD, Nedungadi D, Kline D, Brock G, Simonetti OP, Volek JS, Joseph JJ · The Journal of clinical endocrinology and metabolism · 2022-08-11

Clinical trial / intervention

90. Ketogenic diets composed of long-chain and medium-chain fatty acids induce cardiac fibrosis in mice.

Sternberg F, Sternberg C, Dunkel A, Beikbaghban T, Gregor A, Szarzynski A, Somoza V, Walter I, Duszka K, Kofler B, Pohl EE · Molecular metabolism · 2023-03-21

Systematic review / meta-analysis

91. Effects of ketogenic diet on health outcomes: an umbrella review of meta-analyses of randomized clinical trials.

Patikorn C, Saidoung P, Pham T, Phisalprapa P, Lee YY, Varady KA, Veettil SK, Chaiyakunapruk N · BMC medicine · 2023-05-25

Preclinical / mechanistic

92. A ketogenic diet improves vascular hyperpermeability in type 2 diabetic mice by downregulating vascular pescadillo1 expression.

Wang S, Zhou J, Lu J, Lin Y, Liu S, Chen K · Journal of cellular and molecular medicine · 2023-04-15

Other

93. Highlights From the American College of Cardiology's 2023 Scientific Session: the Ketogenic Diet and Cardiac Events, a Wearable Sensor to Predict Troponin Levels, Bempedoic Acid for Statin Intolerance, and More.

Suran M · JAMA · 2023-04-13

Randomized clinical trial

94. Oral ketone esters acutely improve myocardial contractility in post-hospitalized COVID-19 patients: A randomized placebo-controlled double-blind crossover study.

Wodschow HZ, Davidovski FS, Christensen J, Lassen MCH, Skaarup KG, Nygaard H, Møller N, Rungby J, Biering-Sørensen T, Rossing P, Jensen NJ, Laursen JC · Frontiers in nutrition · 2023-02-09

Preclinical / mechanistic

95. Ketogenic diet modulates cardiac metabolic dysregulation in streptozocin-induced diabetic rats.

Trang NN, Lee TW, Kao YH, Chao TF, Lee TI, Chen YJ · The Journal of nutritional biochemistry · 2022-09-29

Systematic review / meta-analysis

96. Low carbohydrate ketogenic diets reduce cardiovascular risk factor levels in obese or overweight patients with T2DM: A meta-analysis of randomized controlled trials.

Luo W, Zhang J, Xu D, Zhou Y, Qu Z, Yang Q, Lv Q · Frontiers in nutrition · 2022-12-13

Review

97. Comprehensive nutrient consumption estimation and metabolic profiling during ketogenic diet and relationship with myocardial glucose uptake on FDG-PET.

Selvaraj S, Seidelmann SB, Soni M, Bhattaru A, Margulies KB, Shah SH, Dugyala S, Qian C, Pryma DA, Arany Z, Kelly DP, Chirinos JA, Bravo PE · European heart journal. Cardiovascular Imaging · 2021-10-05

Preclinical / mechanistic

98. Ketogenic diet attenuates post-cardiac arrest brain injury by upregulation of pentose phosphate pathway-mediated antioxidant defense in a mouse model of cardiac arrest.

Peng F, Zhang YH, Zhang L, Yang M, Chen C, Yu H, Li T · Nutrition (Burbank, Los Angeles County, Calif.) · 2022-08-12

Clinical trial / intervention

99. The janus face of ketone bodies in hypertension.

Costa TJ, Linder BA, Hester S, Fontes M, Pernomian L, Wenceslau CF, Robinson AT, McCarthy CG · Journal of hypertension · 2022-08-08

Clinical trial / intervention

100. The Effect of Ketogenic Diet on Shared Risk Factors of Cardiovascular Disease and Cancer.

Mohammadifard N, Haghighatdoost F, Rahimlou M, Rodrigues APS, Gaskarei MK, Okhovat P, de Oliveira C, Silveira EA, Sarrafzadegan N · Nutrients · 2022-08-25

Case report / case series

101. Extensive Biventricular Cardiac Sarcoidosis Detected on FDG PET/CT Using a 72-Hour Ketogenic Diet Preparation Protocol.

Lu Y · Clinical nuclear medicine · 2022-03-08

Observational human study

102. Six-month effects of modified Atkins diet implementation on indices of cardiovascular disease risk in adults with epilepsy.

McDonald TJW, Diaz-Arias L, Vizthum D, Henry-Barron BJ, Schlechter H, Kossoff EH, Cervenka MC · Nutritional neuroscience · 2021-01-23

Preclinical / mechanistic

103. Alternate-Day Ketogenic Diet Feeding Protects against Heart Failure through Preservation of Ketogenesis in the Liver.

Guo Y, Liu X, Li T, Zhao J, Yang Y, Yao Y, Wang L, Yang B, Ren G, Tan Y, Jiang S · Oxidative medicine and cellular longevity · 2022-06-06

Randomized clinical trial

104. Comparison of Exogenous Ketone Administration Versus Dietary Carbohydrate Restriction on Myocardial Glucose Suppression: A Crossover Clinical Trial.

Selvaraj S, Margulies KB, Dugyala S, Schubert E, Tierney A, Arany Z, Pryma DA, Shah SH, Rame JE, Kelly DP, Bravo PE · Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2021-10-21

Observational human study

105. A Low-Carbohydrate, High-Fat Ketogenic Diet Program Implemented by an Interdisciplinary Primary Care Team Improves Markers of Cardiometabolic Health in Adults With Type 2 Diabetes: A Retrospective Secondary Analysis.

Neudorf H, Mindrum M, Mindrum C, Durrer C, Little JP · Canadian journal of diabetes · 2021-09-08

Systematic review / meta-analysis

106. Ketogenic diet, African American women, and cardiovascular health: A systematic review.

Hanners A, Melnyk BM, Volek J, Kelley MM · Worldviews on evidence-based nursing · 2022-01-19

Review

107. Ketone bodies: from enemy to friend and guardian angel.

Kolb H, Kempf K, Röhling M, Lenzen-Schulte M, Schloot NC, Martin S · BMC medicine · 2021-12-09

Preclinical / mechanistic

108. Chronic exogenous ketone supplementation blunts the decline of cardiac function in the failing heart.

Takahara S, Soni S, Phaterpekar K, Kim TT, Maayah ZH, Levasseur JL, Silver HL, Freed DH, Ferdaoussi M, Dyck JRB · ESC heart failure · 2021-10-06

Review

109. Ketogenic Diets and Cardio-Metabolic Diseases.

Zhang W, Guo X, Chen L, Chen T, Yu J, Wu C, Zheng J · Frontiers in endocrinology · 2021-11-02

Preclinical / mechanistic

110. A Hypomethylating Ketogenic Diet in Apolipoprotein E-Deficient Mice: A Pilot Study on Vascular Effects and Specific Epigenetic Changes.

Castro R, Whalen CA, Gullette S, Mattie FJ, Florindo C, Heil SG, Huang NK, Neuberger T, Ross AC · Nutrients · 2021-10-13

Preclinical / mechanistic

111. Ketone Ester D-β-Hydroxybutyrate-(R)-1,3 Butanediol Prevents Decline in Cardiac Function in Type 2 Diabetic Mice.

Thai PN, Miller CV, King MT, Schaefer S, Veech RL, Chiamvimonvat N, Bers DM, Dedkova EN · Journal of the American Heart Association · 2021-09-29

Clinical trial / intervention

112. Ketogenic Diet, Physical Activity, and Hypertension-A Narrative Review.

Di Raimondo D, Buscemi S, Musiari G, Rizzo G, Pirera E, Corleo D, Pinto A, Tuttolomondo A · Nutrients · 2021-07-27

Review

113. Novel Nutritional and Dietary Approaches to Weight Loss for the Prevention of Cardiovascular Disease: Ketogenic Diet, Intermittent Fasting, and Bariatric Surgery.

Becker A, Gaballa D, Roslin M, Gianos E, Kane J · Current cardiology reports · 2021-06-03

Systematic review / meta-analysis

114. [Systematic evaluation on efficacy and safety of Gingko Ketone Ester Dropping Pills in treatment of angina pectoris and coronary heart disease].

Wang KY, Wang HC, Jin XY, Zhang MY, Li N, Pang WT, Wang H, Zhang JH · Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica · 2021-05-28

Preclinical / mechanistic

115. Ketogenic Diet Suppressed T-Regulatory Cells and Promoted Cardiac Fibrosis via Reducing Mitochondria-Associated Membranes and Inhibiting Mitochondrial Function.

Tao J, Chen H, Wang YJ, Qiu JX, Meng QQ, Zou RJ, Li L, Huang JG, Zhao ZK, Huang YL, Zhang HF, Zheng JM · Oxidative medicine and cellular longevity · 2021-04-19

Review

116. Effect of the ketogenic diet in excitable tissues.

Murano C, Binda A, Palestini P, Baruscotti M, DiFrancesco JC, Rivolta I · American journal of physiology. Cell physiology · 2021-01-27

Other

117. Exogenous ketones in the healthy heart: the plot thickens.

Selvaraj S, Margulies KB · Cardiovascular research · 2020-10-19

Preclinical / mechanistic

118. Ketogenic diets inhibit mitochondrial biogenesis and induce cardiac fibrosis.

Xu S, Tao H, Cao W, Cao L, Lin Y, Zhao SM, Xu W, Cao J, Zhao JY · Signal transduction and targeted therapy · 2021-02-09

Other

119. Correction to: Impact of a 2‑year trial of nutritional ketosis on indices of cardiovascular disease risk in patients with type 2 diabetes.

Athinarayanan SJ, Hallberg SJ, McKenzie AL, Lechner K, King S, McCarter JP, Volek JS, Phinney SD, Krauss RM · Cardiovascular diabetology · 2021-02-05

Other

120. Myocardial ketone body utilization in patients with heart failure: The impact of oral ketone ester.

Monzo L, Sedlacek K, Hromanikova K, Tomanova L, Borlaug BA, Jabor A, Kautzner J, Melenovsky V · Metabolism: clinical and experimental · 2020-11-26

Preclinical / mechanistic

121. Ketone Ester Treatment Improves Cardiac Function and Reduces Pathologic Remodeling in Preclinical Models of Heart Failure.

Yurista SR, Matsuura TR, Silljé HHW, Nijholt KT, McDaid KS, Shewale SV, Leone TC, Newman JC, Verdin E, van Veldhuisen DJ, de Boer RA, Kelly DP, Westenbrink BD · Circulation. Heart failure · 2020-12-28

Review

122. Effects of ketogenic diet and ketone bodies on the cardiovascular system: Concentration matters.

Nasser S, Vialichka V, Biesiekierska M, Balcerczyk A, Pirola L · World journal of diabetes · 2020-07-31

Randomized clinical trial

123. Impact of a 2-year trial of nutritional ketosis on indices of cardiovascular disease risk in patients with type 2 diabetes.

Athinarayanan SJ, Hallberg SJ, McKenzie AL, Lechner K, King S, McCarter JP, Volek JS, Phinney SD, Krauss RM · Cardiovascular diabetology · 2020-12-08

Clinical trial / intervention

124. Ketogenic diet aggravates cardiac remodeling in adult spontaneously hypertensive rats.

You Y, Guo Y, Jia P, Zhuang B, Cheng Y, Deng H, Wang X, Zhang C, Luo S, Huang B · Nutrition & metabolism · 2020-10-26

Preclinical / mechanistic

125. Ketogenic diet attenuates aging-associated myocardial remodeling and dysfunction in mice.

Yu Y, Wang F, Wang J, Zhang D, Zhao X · Experimental gerontology · 2020-08-16

Clinical trial / intervention

126. Ketogenic diet aggravates hypertension via NF-κB-mediated endothelial dysfunction in spontaneously hypertensive rats.

Guo Y, Wang X, Jia P, You Y, Cheng Y, Deng H, Luo S, Huang B · Life sciences · 2020-07-21

Case report / case series

127. Reversal of Cardiac Hypertrophy With a Ketogenic Diet in a Child With Mitochondrial Disease and Hypertrophic Cardiomyopathy.

Deberles E, Maragnes P, Penniello-Valette MJ, Allouche S, Joubert M · The Canadian journal of cardiology · 2020-04-28

Other

128. An overlooked danger of ketogenic diets: Making the case that ketone bodies induce vascular damage by the same mechanisms as glucose.

Burkitt MJ · Nutrition (Burbank, Los Angeles County, Calif.) · 2020-02-14

Clinical trial / intervention

129. Ketogenic Diet Ameliorates Cardiac Dysfunction via Balancing Mitochondrial Dynamics and Inhibiting Apoptosis in Type 2 Diabetic Mice.

Guo Y, Zhang C, Shang FF, Luo M, You Y, Zhai Q, Xia Y, Suxin L · Aging and disease · 2020-03-09

Preclinical / mechanistic

130. A 1-week extension of a ketogenic diet provides a further decrease in myocardial 18F-FDG uptake and a high detectability of myocarditis with FDG-PET.

Clément A, Boutley H, Poussier S, Pierson J, Lhuillier M, Kolodziej A, Olivier JL, Karcher G, Marie PY, Maskali F · Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2018-08-20

Other

131. Metabolism of Exogenous D-Beta-Hydroxybutyrate, an Energy Substrate Avidly Consumed by the Heart and Kidney.

Cuenoud B, Hartweg M, Godin JP, Croteau E, Maltais M, Castellano CA, Carpentier AC, Cunnane SC · Frontiers in nutrition · 2020-02-19

Randomized clinical trial

132. Cardiometabolic risk and effectiveness of the modified Atkins Ketogenic Diet for adult patients with pharmacoresistant epilepsies in a middle-income country.

de Souza Neves G, Dos Santos Lunardi M, Papini Gabiatti M, Kurrle Rieger Venske D, Ribeiro LC, Lin K, Dubois Moreira J · Epilepsy research · 2020-01-16

Clinical trial / intervention

133. Modified ketogenic diet is associated with improved cerebrospinal fluid biomarker profile, cerebral perfusion, and cerebral ketone body uptake in older adults at risk for Alzheimer's disease: a pilot study.

Neth BJ, Mintz A, Whitlow C, Jung Y, Solingapuram Sai K, Register TC, Kellar D, Lockhart SN, Hoscheidt S, Maldjian J, Heslegrave AJ, Blennow K, Cunnane SC, Castellano CA, Zetterberg H, Craft S · Neurobiology of aging · 2019-09-26

Preclinical / mechanistic

134. A Calorie-Restricted Ketogenic Diet Reduces Cerebral Cortex Vascularization in Prepubertal Rats.

Viggiano A, Meccariello R, Santoro A, Secondulfo C, Operto FF, Monda M, Coppola G · Nutrients · 2019-11-05

Clinical trial / intervention

135. Lysosomal Acid Lipase as a Molecular Target of the Very Low Carbohydrate Ketogenic Diet in Morbidly Obese Patients: The Potential Effects on Liver Steatosis and Cardiovascular Risk Factors.

Ministrini S, Calzini L, Nulli Migliola E, Ricci MA, Roscini AR, Siepi D, Tozzi G, Daviddi G, Martorelli EE, Paganelli MT, Lupattelli G · Journal of clinical medicine · 2019-05-07

Preclinical / mechanistic

136. Cardiac metabolic modulation upon low-carbohydrate low-protein ketogenic diet in diabetic rats studied in vivo using hyperpolarized 13 C pyruvate, butyrate and acetoacetate probes.

Abdurrachim D, Teo XQ, Woo CC, Ong SY, Salleh NF, Lalic J, Tan RS, Lee PTH · Diabetes, obesity & metabolism · 2019-01-13

Case report / case series

137. Modified Atkins ketogenic diet improves heart and skeletal muscle function in glycogen storage disease type III.

Francini-Pesenti F, Tresso S, Vitturi N · Acta myologica : myopathies and cardiomyopathies : official journal of the Mediterranean Society of Myology · 2019-03-01

Preclinical / mechanistic

138. Short-term and long-term ketogenic diet therapy and the addition of exercise have differential impacts on metabolic gene expression in the mouse energy-consuming organs heart and skeletal muscle.

Shimizu K, Saito H, Sumi K, Sakamoto Y, Tachi Y, Iida K · Nutrition research (New York, N.Y.) · 2018-09-19

Observational human study

139. 10 patients, 10 years - Long term follow-up of cardiovascular risk factors in Glut1 deficiency treated with ketogenic diet therapies: A prospective, multicenter case series.

Heussinger N, Della Marina A, Beyerlein A, Leiendecker B, Hermann-Alves S, Dalla Pozza R, Klepper J · Clinical nutrition (Edinburgh, Scotland) · 2017-11-11

Other

140. Cardiovascular Risks of Ketogenic Diet for Glut-1 Deficiency.

Spalice A, Guido CA · Pediatric neurology briefs · 2018-09-05

Randomized clinical trial

141. Cardiovascular disease risk factor responses to a type 2 diabetes care model including nutritional ketosis induced by sustained carbohydrate restriction at 1 year: an open label, non-randomized, controlled study.

Bhanpuri NH, Hallberg SJ, Williams PT, McKenzie AL, Ballard KD, Campbell WW, McCarter JP, Phinney SD, Volek JS · Cardiovascular diabetology · 2018-05-01

Clinical trial / intervention

142. Ketogenic diet enhances neurovascular function with altered gut microbiome in young healthy mice.

Ma D, Wang AC, Parikh I, Green SJ, Hoffman JD, Chlipala G, Murphy MP, Sokola BS, Bauer B, Hartz AMS, Lin AL · Scientific reports · 2018-04-27

Other

143. Impact of the modified Atkins diet on cardiovascular health in adults with epilepsy.

McDonald TJW, Ratchford EV, Henry-Barron BJ, Kossoff EH, Cervenka MC · Epilepsy & behavior : E&B · 2017-12-15

Randomized clinical trial

144. The effect of a ketogenic diet versus a high-carbohydrate, low-fat diet on sleep, cognition, thyroid function, and cardiovascular health independent of weight loss: study protocol for a randomized controlled trial.

Iacovides S, Meiring RM · Trials · 2018-01-23

Review

145. [Ketogenic diets : the miraculous solution ?].

Kosinski C, Jornayvaz FR · Revue medicale suisse · 2017-06-23

Review

146. Effects of Ketogenic Diets on Cardiovascular Risk Factors: Evidence from Animal and Human Studies.

Kosinski C, Jornayvaz FR · Nutrients · 2017-05-19

Preclinical / mechanistic

147. Streptozotocin diabetes increases mRNA expression of ketogenic enzymes in the rat heart.

Cook GA, Lavrentyev EN, Pham K, Park EA · Biochimica et biophysica acta. General subjects · 2016-11-11

Observational human study

148. Does ketogenic diet have any negative effect on cardiac systolic and diastolic functions in children with intractable epilepsy?: One-year follow-up results.

Ozdemir R, Kucuk M, Guzel O, Karadeniz C, Yilmaz U, Mese T · Brain & development · 2016-04-05

Observational human study

149. An observational study of sequential protein-sparing, very low-calorie ketogenic diet (Oloproteic diet) and hypocaloric Mediterranean-like diet for the treatment of obesity.

Castaldo G, Monaco L, Castaldo L, Galdo G, Cereda E · International journal of food sciences and nutrition · 2016-05-18

Observational human study

150. The Impact of 3:1 Ketogenic Diet on Cardiac Repolarization Changes in Children with Refractory Seizures: A Prospective Follow-Up Study.

Özdemir R, Güzel O, Küçük M, Karadeniz C, Yılmaz Ü, Calik T, Meşe T · Neuropediatrics · 2016-04-04

Observational human study

151. Middle and Long-Term Impact of a Very Low-Carbohydrate Ketogenic Diet on Cardiometabolic Factors: A Multi-Center, Cross-Sectional, Clinical Study.

Cicero AF, Benelli M, Brancaleoni M, Dainelli G, Merlini D, Negri R · High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2015-05-19

Observational human study

152. The Short-Term Effects of Ketogenic Diet on Cardiac Ventricular Functions in Epileptic Children.

Doksöz Ö, Çeleğen K, Güzel O, Yılmaz Ü, Uysal U, İşgüder R, Çeleğen M, Meşe T · Pediatric neurology · 2015-06-18

Preclinical / mechanistic

153. Neurological and cardiac responses after treatment with miglustat and a ketogenic diet in a patient with Sandhoff disease.

Villamizar-Schiller IT, Pabón LA, Hufnagel SB, Serrano NC, Karl G, Jefferies JL, Hopkin RJ, Prada CE · European journal of medical genetics · 2014-12-12

Randomized clinical trial

154. Effects of n-3 polyunsaturated fatty acids (ω-3) supplementation on some cardiovascular risk factors with a ketogenic Mediterranean diet.

Paoli A, Moro T, Bosco G, Bianco A, Grimaldi KA, Camporesi E, Mangar D · Marine drugs · 2015-02-13

Other

155. Effects of ketogenic diet on vascular function.

Kapetanakis M, Liuba P, Odermarsky M, Lundgren J, Hallböök T · European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society · 2014-03-25

Other

156. The impact of the ketogenic diet on arterial morphology and endothelial function in children and young adults with epilepsy: a case-control study.

Coppola G, Natale F, Torino A, Capasso R, D'Aniello A, Pironti E, Santoro E, Calabrò R, Verrotti A · Seizure · 2013-12-12

Review

157. Beyond weight loss: a review of the therapeutic uses of very-low-carbohydrate (ketogenic) diets.

Paoli A, Rubini A, Volek JS, Grimaldi KA · European journal of clinical nutrition · 2013-06-26

Case report / case series

158. Ketogenic diet: rapid onset of selenium deficiency-induced cardiac decompensation.

Sirikonda NS, Patten WD, Phillips JR, Mullett CJ · Pediatric cardiology · 2012-02-25

Preclinical / mechanistic

159. Lethal mitochondrial cardiomyopathy in a hypomorphic Med30 mouse mutant is ameliorated by ketogenic diet.

Krebs P, Fan W, Chen YH, Tobita K, Downes MR, Wood MR, Sun L, Li X, Xia Y, Ding N, Spaeth JM, Moresco EM, Boyer TG, Lo CW, Yen J, Evans RM, Beutler B · Proceedings of the National Academy of Sciences of the United States of America · 2011-11-21

Other

160. Effect of ketogenic Mediterranean diet with phytoextracts and low carbohydrates/high-protein meals on weight, cardiovascular risk factors, body composition and diet compliance in Italian council employees.

Paoli A, Cenci L, Grimaldi KA · Nutrition journal · 2011-10-12

Review

161. [The ketogenic diet: an underappreciated therapeutic option?].

Paoli A, Canato M, Toniolo L, Bargossi AM, Neri M, Mediati M, Alesso D, Sanna G, Grimaldi KA, Fazzari AL, Bianco A · La Clinica terapeutica · 2011-11-02

Preclinical / mechanistic

162. PPARα deficiency augments a ketogenic diet-induced circadian PAI-1 expression possibly through PPARγ activation in the liver.

Oishi K, Uchida D, Ohkura N, Horie S · Biochemical and biophysical research communications · 2010-09-18

Preclinical / mechanistic

163. Adaptation of myocardial substrate metabolism to a ketogenic nutrient environment.

Wentz AE, d'Avignon DA, Weber ML, Cotter DG, Doherty JM, Kerns R, Nagarajan R, Reddy N, Sambandam N, Crawford PA · The Journal of biological chemistry · 2010-06-07

Other

164. Low-carbohydrate ketogenic diet and the combination of orlistat with a low-fat diet lead to comparable improvements in weight and blood lipids, but LCKD more beneficial for blood pressure.

Gardner CD · Evidence-based medicine · 2010-06-05

Preclinical / mechanistic

165. Intracisternal administration of glibenclamide or 5-hydroxydecanoate does not reverse the neuroprotective effect of ketogenic diet against ischemic brain injury-induced neurodegeneration.

Tai KK, Pham L, Truong DD · Brain injury · 2009-11-14

Preclinical / mechanistic

166. Ketogenic diet disrupts the circadian clock and increases hypofibrinolytic risk by inducing expression of plasminogen activator inhibitor-1.

Oishi K, Uchida D, Ohkura N, Doi R, Ishida N, Kadota K, Horie S · Arteriosclerosis, thrombosis, and vascular biology · 2009-07-23

Preclinical / mechanistic

167. A ketogenic diet increases succinic dehydrogenase activity in aging cardiomyocytes.

Balietti M, Fattoretti P, Giorgetti B, Casoli T, Di Stefano G, Solazzi M, Platano D, Aicardi G, Bertoni-Freddari C · Annals of the New York Academy of Sciences · 2009-09-03

Other

168. [Ketogenic diets: additional benefits to the weight loss and unfounded secondary effects].

Pérez-Guisado J · Archivos latinoamericanos de nutricion · 2009-04-17

Case report / case series

169. Sudden cardiac death in association with the ketogenic diet.

Bank IM, Shemie SD, Rosenblatt B, Bernard C, Mackie AS · Pediatric neurology · 2007-09-14

Observational human study

170. Spanish Ketogenic Mediterranean Diet: a healthy cardiovascular diet for weight loss.

Pérez-Guisado J, Muñoz-Serrano A, Alonso-Moraga A · Nutrition journal · 2008-10-26

Preclinical / mechanistic

171. Ketogenic diet prevents cardiac arrest-induced cerebral ischemic neurodegeneration.

Tai KK, Nguyen N, Pham L, Truong DD · Journal of neural transmission (Vienna, Austria : 1996) · 2008-05-14

Preclinical / mechanistic

172. Ketogenic diet prevents seizure and reduces myoclonic jerks in rats with cardiac arrest-induced cerebral hypoxia.

Tai KK, Truong DD · Neuroscience letters · 2007-08-10

Other

173. Ketogenic diet: electrophysiological effects on the normal human cortex.

Cantello R, Varrasi C, Tarletti R, Cecchin M, D'Andrea F, Veggiotti P, Bellomo G, Monaco F · Epilepsia · 2007-06-11

Clinical trial / intervention

174. Low carbohydrate ketogenic diet enhances cardiac tolerance to global ischaemia.

Al-Zaid NS, Dashti HM, Mathew TC, Juggi JS · Acta cardiologica · 2007-09-11

Clinical trial / intervention

175. Cardiovascular and hormonal aspects of very-low-carbohydrate ketogenic diets.

Volek JS, Sharman MJ · Obesity research · 2004-12-17

Preclinical / mechanistic

176. Lack of long-term histopathologic changes in brain and skeletal muscle of mice treated with a ketogenic diet.

Rho JM, Sarnat HB, Sullivan PG, Robbins CA, Kim DW · Journal of child neurology · 2004-11-06

Other

177. Ketogenic diet modifies the risk factors of heart disease in obese patients.

Dashti HM, Bo-Abbas YY, Asfar SK, Mathew TC, Hussein T, Behbahani A, Khoursheed MA, Al-Sayer HM, Al-Zaid NS · Nutrition (Burbank, Los Angeles County, Calif.) · 2003-10-16

Other

178. A ketogenic diet favorably affects serum biomarkers for cardiovascular disease in normal-weight men.

Sharman MJ, Kraemer WJ, Love DM, Avery NG, Gómez AL, Scheett TP, Volek JS · The Journal of nutrition · 2002-07-05

Case report / case series

179. Cardiac complications in pediatric patients on the ketogenic diet.

Best TH, Franz DN, Gilbert DL, Nelson DP, Epstein MR · Neurology · 2000-07-06

Other

180. The keto cure? Exploring ketogenic diet in heart failure with preserved ejection fraction.

Ansharullah BA, Adytia GJ, Waitupu A, Sutanto H · The Journal of physiology · 2025-05-27

Preclinical / mechanistic

181. Ketogenic diet and ketone salts differentially improve cardiometabolic complications in an HFpEF rat model.

Gonçalves A, Alves IN, Mendes C, Miranda D, Conceição G, Almeida-Coelho J, Martins D, Miranda I, Rodrigues A, Silva C, Oliveira SM, Sereno J, Ferreira MJ, Dischinger U, Girão H, Leite-Moreira AF, Sequeira V, Falcão-Pires I · The Journal of physiology · 2025-04-03

Randomized clinical trial

182. Should Exogenous Ketone Body Supplementation Be Considered in Patients Hospitalized for Acute Heart Failure? Rationale and Design of the KETO-AHF Trial.

Berg-Hansen K, Tinggaard AB, Nielsen R, Jensen TH, Gopalasingam N, Larsen AH, Møller N, Böttcher M, Hollingdal M, Poulsen MK, Antonsen L, Kondo T, Jhund PS, Borlaug BA, Mebazaa A, Møller JE, Vraa S, Grand J, Hove JD, Wolsk E, Schou M, Wiggers H · Journal of cardiac failure · 2025-08-09

Preclinical / mechanistic

183. Protective effects of ketogenic diet on aldosterone-induced atherosclerosis in ApoE-/- mice.

Armani A, Marzolla V, Mammi C, Vitiello L, Bellucci E, Feraco A, Gorini S, Caprio M · Journal of endocrinological investigation · 2025-11-06

Clinical trial / intervention

184. Ketogenic diet and β-hydroxybutyrate inhibit HDAC1 to preserve vascular smooth muscle cell function in thoracic aortic aneurysm.

Weng X, Pan L, Ma X, Luo W, Su H, Pei Z, Dong Z, Liu L, Yang J, Gao P, Sun A · Journal of advanced research · 2025-05-19

Observational human study

185. Utility of serum blood ketone levels and other risk factors for inadequate myocardial glucose suppression ketogenic FDG-PET/CT: a prospective and retrospective cohort study.

Huo YR, Gupta S, Rutherford N, Saul M, Chan MV · Annals of nuclear medicine · 2025-12-15

Observational human study

186. Carotid intima-media thickness may be an early biomarker for cardiovascular risk in patients treated with ketogenic dietary therapy.

Haavardsholm KC, Zamani M, Skjelland M, Ramm-Pettersen A, Skagen K · Epilepsia open · 2025-09-30

Randomized clinical trial

187. Crossover Trial of Exogenous Ketones on Cardiometabolic Endpoints in Heart Failure With Preserved Ejection Fraction.

Selvaraj S, Karaj A, Chirinos JA, Denney N, Grosso G, Fernando M, Chambers K, Demastus C, Reddy R, Langham M, Kumar D, Maynard H, Pourmussa B, Prenner SB, Cohen JB, Ischiropoulos H, Rickels MR, Poole DC, Church DD, Wolfe RR, Kelly DP, Putt M, Margulies KB, Zamani P · JACC. Heart failure · 2025-03-29

Randomized clinical trial

188. Effect of a Ketogenic Diet, Time-Restricted Eating or Alternate-Day Fasting on changes in ambulatory blood pressure. A sub-analysis of a randomized clinical trial.

Gómez-Pérez AM, Bandera-Merchán B, Martínez-Montoro JI, Gutiérrez-Bedmar M, Díaz-Perdigones C, Subiri-Verdugo A, Moreno-Indias I, Tinahones FJ · European journal of preventive cardiology · 2025-09-05

Review

189. Epigenetic regulation by ketone bodies in cardiac diseases and repair.

Gurusamy N, Almalki B, Katragadda S, Murray J, Speth R, Robison L · Canadian journal of physiology and pharmacology · 2025-05-07

Randomized clinical trial

190. Comparative Effects of Time-Restricted Eating and the Ketogenic Diet on QRISK3-Assessed Cardiovascular Risk in Individuals with Obesity: A Longitudinal Analysis of Metabolic, Anthropometric, and Lifestyle Factors.

Pescari D, Mihuta MS, Bena A, Stoian D · Nutrients · 2025-06-09

Clinical trial / intervention

191. Low-Calorie, High-Protein Ketogenic Diet Versus Low-Calorie, Low-Sodium, and High-Potassium Mediterranean Diet in Overweight Patients and Patients with Obesity with High-Normal Blood Pressure or Grade I Hypertension: The Keto-Salt Pilot Study.

Landolfo M, Stella L, Gezzi A, Spannella F, Turri P, Sabbatini L, Cecchi S, Lucchetti B, Petrelli M, Sarzani R · Nutrients · 2025-05-20

Other

192. Intrinsic Ketogenic Capacity of the Heart: Mechanisms and Therapeutic Potential.

Caputo R, Greco CM · Circulation research · 2025-05-08

Preclinical / mechanistic

193. The Heart Has Intrinsic Ketogenic Capacity that Mediates NAD+ Therapy in HFpEF.

Koay YC, McIntosh B, Ng YH, Cao Y, Wang XS, Han Y, Tomita S, Bai AY, Hunter B, Misra A, Loughrey CM, Bannon PG, Lal S, Lusis AJ, Kaye DM, Larance M, O'Sullivan JF · Circulation research · 2025-04-11

Clinical trial / intervention

194. Ketogenic diet improves disease activity and cardiovascular risk in psoriatic arthritis: A proof of concept study.

Ramonda R, Ometto F, Striani G, Cozzi G, Basso D, Evangelista F, Lorenzin M, Scagnellato L, Aita A, Favero M, Brocadello F, Doria A · PloS one · 2025-04-22

Randomized clinical trial

195. Effect of the modified Atkins diet on NLRP3, caspase-1, IL-ιβ, and IL-10 in patients with tetralogy of Fallot undergoing open-heart surgery: A randomized controlled trial.

Yanuarso PB, Djer MM, Hendarto A, Pudjiadi AH, Rachmadi L, Wibowo H, Advani N, Murni IK, Kekalih A, Sukardi R, Dilawar I, Susanti DS, Supriatna N · Narra J · 2025-03-24

Kidney & Urology

ADPKD Recent peer-reviewed literature

Source-audited references from the connected PDF archive. Only papers directly relevant to this topic and ketogenic therapy/ketosis are shown.

1. β-Hydroxybutyrate: a renoprotective hormone in polycystic kidney disease

Bibliographic record reviewed for inclusion in the curated Scientific Library.

2. Nutritional adequacy of ketogenic diets as a novel dietary intervention for people living with ADPKD

Bibliographic record reviewed for inclusion in the curated Scientific Library.

3. Ketogenic dietary interventions for autosomal-dominant polycystic kidney disease

Bibliographic record reviewed for inclusion in the curated Scientific Library.

4. β-Hydroxybutyrate recapitulates the beneficial effects of ketogenic metabolic therapy in polycystic kidney disease

Bibliographic record reviewed for inclusion in the curated Scientific Library.

5. Ketogenic Interventions in Autosomal Dominant Polycystic Kidney Disease: A Comprehensive Review of Current Evidence

Bibliographic record reviewed for inclusion in the curated Scientific Library.

6. Feasibility and impact of ketogenic dietary interventions in ADPKD

Bibliographic record reviewed for inclusion in the curated Scientific Library.

7. A pilot study to evaluate tolerability and safety of a modified Atkins diet in autosomal dominant polycystic kidney disease

Bibliographic record reviewed for inclusion in the curated Scientific Library.

8. GREASE II: randomized trial of ketogenic metabolic therapy in autosomal dominant polycystic kidney disease

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Clinical trial / intervention

9. Plant-based ketogenic nutritional intervention in a young woman with autosomal dominant polycystic kidney disease: A case report.

Alvarado-Pelayo PA, García-Rodríguez XN, Gómez-García EF, Cisneros-Hernández A · Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition · 2026-07-13

Clinical trial / intervention

10. Halting cyst progression in ADPKD using long-term ketogenic metabolic therapy and supplementation with exogenous ketones and alkaline citrate-a case series.

Messing M, Muensterman E, Marcon S, Weimbs T · Frontiers in nutrition · 2026-06-29

Other

11. Correction to: Kidney Week 2025 Abstract Three-Month Interim Analysis of Ketogenic Metabolic Therapy in Japanese Patients with ADPKD SA-PO0579.

Kawano H, Koizumi W, Lu Y, Kimura T, Ikehata Y, Muto S, Kuo CY, Muensterman EG, Paimanta C, Welsh KL, Saville J, Weimbs T, Horie S · Journal of the American Society of Nephrology : JASN · 2025-12-26

Systematic review / meta-analysis

12. Therapeutic Potential of Ketogenic Interventions for Autosomal-Dominant Polycystic Kidney Disease: A Systematic Review.

Li D, Dawson J, Gunton JE · Nutrients · 2024-12-31

Other

13. Exploring the role of ketogenic diet in ADPKD treatment: A promising avenue.

Mutaal A, Shehzad D, Samdani K · JPMA. The Journal of the Pakistan Medical Association · 2024-11-16

Randomized clinical trial

14. Feasibility and impact of ketogenic dietary interventions in polycystic kidney disease: KETO-ADPKD-a randomized controlled trial.

Cukoski S, Lindemann CH, Arjune S, Todorova P, Brecht T, Kühn A, Oehm S, Strubl S, Becker I, Kämmerer U, Torres JA, Meyer F, Schömig T, Hokamp NG, Siedek F, Gottschalk I, Benzing T, Schmidt J, Antczak P, Weimbs T, Grundmann F, Müller RU · Cell reports. Medicine · 2023-11-07

Clinical trial / intervention

15. RESET-PKD: a pilot trial on short-term ketogenic interventions in autosomal dominant polycystic kidney disease.

Oehm S, Steinke K, Schmidt J, Arjune S, Todorova P, Heinrich Lindemann C, Wöstmann F, Meyer F, Siedek F, Weimbs T, Müller RU, Grundmann F · Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2022-05-25

Clinical trial / intervention

16. Ketogenic dietary interventions in autosomal dominant polycystic kidney disease-a retrospective case series study: first insights into feasibility, safety and effects.

Strubl S, Oehm S, Torres JA, Grundmann F, Haratani J, Decker M, Vuong S, Kaur Bhandal A, Methot N, Haynie-Cion R, Meyer F, Siedek F, Korst U, Müller RU, Weimbs T · Clinical kidney journal · 2021-09-13

Clinical trial / intervention

17. Can ketogenic dietary interventions slow disease progression in ADPKD: what we know and what we don't.

Ong ACM, Torra R · Clinical kidney journal · 2022-04-21

Chronic Kidney Disease Recent peer-reviewed literature

Source-audited selection from the connected PDF archive. Systematic reviews/meta-analyses and recent human evidence are prioritized when available; sparse areas are explicitly kept sparse.

Review

1. Ketogenic Diets in Chronic Kidney Disease Patients: A Review for Skeptics by Skeptics

Original publication title: Ketogenic Diets in Chronic Kidney Disease Patients: A Review for Skeptics by Skeptics

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Review

2. Ketone Bodies in Kidney Diseases

Original publication title: Ketone Bodies in Kidney Diseases

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Review

3. Ketogenic Diets and β-Hydroxybutyrate in Kidney Disease

Original publication title: Ketogenic Diets and β-Hydroxybutyrate in Kidney Disease

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Review

4. The Case for a Ketogenic Diet in the Management of Kidney Disease

Original publication title: The Case for a Ketogenic Diet in the Management of Kidney Disease

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Critical review

5. Risks of the Ketogenic Diet in Chronic Kidney Disease

Original publication title: Risks of the Ketogenic Diet in Chronic Kidney Disease

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Clinical/review evidence

6. Ketogenic Metabolic Therapy for Chronic Kidney Disease

Original publication title: Ketogenic Metabolic Therapy for Chronic Kidney Disease

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Human clinical study

7. Very Low-Calorie Ketogenic Diet: A Safe and Effective Tool for Weight Loss in Patients with Obesity and Mild Kidney Failure

Original publication title: Very Low-Calorie Ketogenic Diet: A Safe and Effective Tool for Weight Loss in Patients with Obesity and Mild Kidney Failure

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Mechanistic study

8. BDH1-Mediated β-Hydroxybutyrate Metabolism Ameliorates Diabetic Kidney Disease

Original publication title: BDH1-Mediated β-Hydroxybutyrate Metabolism Ameliorates Diabetic Kidney Disease

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Preclinical mechanistic study

9. 3-Hydroxybutyrate Ameliorates the Progression of Diabetic Nephropathy

Original publication title: 3-Hydroxybutyrate Ameliorates the Progression of Diabetic Nephropathy

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Systematic review / safety evidence

10. Incidence and Characteristics of Kidney Stones in Patients on Ketogenic Diets

Original publication title: Incidence and Characteristics of Kidney Stones in Patients on Ketogenic Diets

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Clinical trial / intervention

11. Plant-based ketogenic nutritional intervention in a young woman with autosomal dominant polycystic kidney disease: A case report.

Alvarado-Pelayo PA, García-Rodríguez XN, Gómez-García EF, Cisneros-Hernández A · Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition · 2026-07-13

Review

12. Ketone bodies in kidney diseases: novel insights.

Dai W, Zhang W, Li H, Gao Y, Xiao L, Chen Y, He L · Frontiers in immunology · 2026-06-15

Clinical trial / intervention

13. The ketogenic diet is not for everyone: contraindications, side effects, and drug interactions.

Dyńka D, Rodzeń Ł, Rodzeń M, Łojko D, Karakuła-Juchnowicz H, Ede G, Grzywacz Ż, Antosik K, Sethi S, Unwin D · Annals of medicine · 2026-01-04

Systematic review / meta-analysis

14. Therapeutic Potential of Ketogenic Interventions for Autosomal-Dominant Polycystic Kidney Disease: A Systematic Review.

Li D, Dawson J, Gunton JE · Nutrients · 2024-12-31

Preclinical / mechanistic

15. Ketogenic Diet and Progression of Kidney Disease in Animal Models of Nephropathic Cystinosis.

Bellomo F, Pugliese S, Cairoli S, Krohn P, De Stefanis C, Raso R, Rega LR, Taranta A, De Leo E, Ciolfi A, Cicolani N, Petrini S, Luciani A, Goffredo BM, Porzio O, Devuyst O, Dionisi-Vici C, Emma F · Journal of the American Society of Nephrology : JASN · 2024-07-12

Clinical trial / intervention

16. Ketogenic metabolic therapy for chronic kidney disease - the pro part.

Weimbs T, Saville J, Kalantar-Zadeh K · Clinical kidney journal · 2023-11-07

Review

17. Risks of the ketogenic diet in CKD - the con part.

Joshi S, Shi R, Patel J · Clinical kidney journal · 2023-11-07

Clinical trial / intervention

18. Effects of Ketogenic Diet Intervention on Metabolic Acidosis in Patients with Obesity and Chronic Kidney Disease.

De Almeida RJR, Jaber F, Rajab R, Zatreh M, Cabandugama P, Bader N · Missouri medicine · 2023-12-26

Preclinical / mechanistic

19. Ketogenic diet alleviates renal interstitial fibrosis in UUO mice by regulating macrophage proliferation.

Hu X, Qiu Y, Cao R, Xu C, Lu C, Wang Z, Yang J · The Journal of nutritional biochemistry · 2023-04-05

Clinical trial / intervention

20. RESET-PKD: a pilot trial on short-term ketogenic interventions in autosomal dominant polycystic kidney disease.

Oehm S, Steinke K, Schmidt J, Arjune S, Todorova P, Heinrich Lindemann C, Wöstmann F, Meyer F, Siedek F, Weimbs T, Müller RU, Grundmann F · Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2022-05-25

Clinical trial / intervention

21. The janus face of ketone bodies in hypertension.

Costa TJ, Linder BA, Hester S, Fontes M, Pernomian L, Wenceslau CF, Robinson AT, McCarthy CG · Journal of hypertension · 2022-08-08

Clinical trial / intervention

22. Potentials of ketogenic diet against chronic kidney diseases: pharmacological insights and therapeutic prospects.

Kundu S, Hossain KS, Moni A, Zahan MS, Rahman MM, Uddin MJ · Molecular biology reports · 2022-04-20

Clinical trial / intervention

23. Ketogenic dietary interventions in autosomal dominant polycystic kidney disease-a retrospective case series study: first insights into feasibility, safety and effects.

Strubl S, Oehm S, Torres JA, Grundmann F, Haratani J, Decker M, Vuong S, Kaur Bhandal A, Methot N, Haynie-Cion R, Meyer F, Siedek F, Korst U, Müller RU, Weimbs T · Clinical kidney journal · 2021-09-13

Preclinical / mechanistic

24. Ketogenic diet aggravates kidney dysfunction by exacerbating metabolic disorders and inhibiting autophagy in spontaneously hypertensive rats.

Jia P, Huang B, You Y, Su H, Gao L · Biochemical and biophysical research communications · 2021-08-03

Other

25. Very Low-Calorie Ketogenic Diets to Treat Patients With Obesity and Chronic Kidney Disease.

Masi D, Risi R, Basciani S, Tuccinardi D, Mariani S, Lubrano C, Gnessi L, Watanabe M · Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation · 2020-10-22

Observational human study

26. Ketogenic Diet, Serum Ketone Bodies and Risk of End-Stage Renal Disease in Patients With Diabetic Kidney Disease: A Multi-Cohort Study.

Liu K, Yang Q, Lang Y, Zou Y, Yuan J, Yang J, Ma J, Cai L, Kong X, Yang F, Liu F · Journal of diabetes · 2025-06-11

Review

27. Ketone bodies in renal function and diabetic kidney disease.

Mechchate H · The Journal of nutritional biochemistry · 2025-04-03

Randomized clinical trial

28. Effects of a continuous remote care intervention including nutritional ketosis on kidney function and inflammation in adults with type 2 diabetes: a post-hoc latent class trajectory analysis.

Athinarayanan SJ, Roberts CGP, Phinney SD, Weimbs T, Friedman AN, Volek JS · Frontiers in nutrition · 2025-06-06

Review

29. Ketogenic diets and β-hydroxybutyrate in the prevention and treatment of diabetic kidney disease: current progress and future perspectives.

Li J, He W, Wu Q, Qin Y, Luo C, Dai Z, Long Y, Yan P, Huang W, Cao L · BMC nephrology · 2025-03-07

Urinary Incontinence Recent peer-reviewed literature

Source-audited selection from the connected PDF archive. Systematic reviews/meta-analyses and recent human evidence are prioritized when available; sparse areas are explicitly kept sparse.

Case series · 2022

1. Ketogenic Diet May Be a New Approach to Treat Stress Urinary Incontinence in Obese Elderly Women: Report of Five Cases

Original publication title: Ketogenic Diet May Be a New Approach to Treat Stress Urinary Incontinence in Obese Elderly Women: Report of Five Cases

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Case report / case series

2. Ketogenic diet may be a new approach to treatment stress urinary incontinence in obese elderly women: report of five cases.

Sun Y, Chen H, Bai Y, Zhang T, Bai W, Jiang B · BMC women's health · 2022-10-04

Musculoskeletal

Sarcopenia & Skeletal Muscle Recent peer-reviewed literature

Evidence is ordered preferentially by systematic reviews/meta-analyses and recent high-level evidence, followed by recent clinical studies and then relevant mechanistic work.

Human intervention

1. VLCKD in Combination with Physical Exercise Preserves Skeletal Muscle in Obesity

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Human intervention

2. VLCKD combined with physical interval training

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Human clinical study

3. Impact of a Very Low-Calorie Ketogenic Diet (VLCKD) on Changes in Handgrip Strength in Women with Obesity

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Preclinical mechanistic study

4. Ketogenic diet preserves muscle mass and strength in a mouse model of type 2 diabetes

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Review

5. Emerging Nutrition Approaches to Support the Mind and Muscle for Healthy Aging

Original publication title: Emerging Nutrition Approaches to Support the Mind and Muscle for Healthy Aging

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Preclinical / translational study

6. Effects of a ketogenic diet on motor function and motor unit number

Original publication title: Effects of a ketogenic diet on motor function and motor unit number

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Preclinical / mechanistic

7. Effects of aging in combination with high-fat or ketogenic diet on skeletal muscle hypertrophy after functional overloading in C57BL/6J mice.

Dirmontas M, Minderis P, Ratkevicius A · Growth factors (Chur, Switzerland) · 2026-07-19

Preclinical / mechanistic

8. Semaglutide-induced loss of skeletal muscle mass is blunted by co-administration of ketone esters.

Abuetabh Y, Schmidt MA, Naganuma M, Vaka R, El-Ghiaty MA, Braun S, Kwan EA, Zolondek MC, Sahid D, Khan L, Shandal RK, Trudeau AL, Li Y, Malik SO, Sun Q, Roth DK, Morales-Llamas DY, Levasseur JL, Ferdaoussi M, Fahlman RP, Dyck JR · JCI insight · 2026-06-09

Review

9. Ketogenic diet in treating sepsis-related acquired weakness: is it friend or foe?

Miao Y, Xie L, Chen S, Zhang X, Liu W, Xie P · Frontiers in nutrition · 2024-11-28

Randomized clinical trial

10. A 3-Week Ketogenic Diet Increases Skeletal Muscle Insulin Sensitivity in Individuals With Obesity: A Randomized Controlled Crossover Trial.

Luong TV, Pedersen MGB, Abild CB, Lauritsen KM, Kjærulff MLG, Møller N, Gormsen LC, Søndergaard E · Diabetes · 2024-02-28

Clinical trial / intervention

11. Metabolic Effects of Ketogenic Diets: Exploring Whole-Body Metabolism in Connection with Adipose Tissue and Other Metabolic Organs.

Ahmad Y, Seo DS, Jang Y · International journal of molecular sciences · 2024-06-27

Randomized clinical trial

12. Effects of a ketogenic diet on motor function and motor unit number estimation in aged C57BL/6 mice.

Padilla CJ, Harris H, Volek JS, Clark BC, Arnold WD · The journal of nutrition, health & aging · 2024-04-05

Preclinical / mechanistic

13. Ketogenic diet ameliorates high-fat diet-induced insulin resistance in mouse skeletal muscle by alleviating endoplasmic reticulum stress.

Ma Q, Jiang L, You Y, Ni H, Ma L, Lin X, Wang Z, Yan W, Xiao X, Li X, Li J · Biochemical and biophysical research communications · 2024-02-05

Randomized clinical trial

14. Ketogenic Diet Improves Motor Function and Motor Unit Connectivity in Aged C57BL/6 Mice.

Padilla CJ, Harris H, Volek JS, Clark BC, Arnold WD · Research square · 2023-10-27

Other

15. Ketogenic Diets and Mitochondrial Function: Benefits for Aging But Not for Athletes.

Pathak SJ, Baar K · Exercise and sport sciences reviews · 2022-09-16

Preclinical / mechanistic

16. Ketogenic diet containing medium-chain triglyceride ameliorates transcriptome disruption in skeletal muscles of rat models of duchenne muscular dystrophy.

Fujikura Y, Yamanouchi K, Sugihara H, Hatakeyama M, Abe T, Ato S, Oishi K · Biochemistry and biophysics reports · 2022-11-11

Clinical trial / intervention

17. VLCKD in Combination with Physical Exercise Preserves Skeletal Muscle Mass in Sarcopenic Obesity after Severe COVID-19 Disease: A Case Report.

Camajani E, Feraco A, Basciani S, Gnessi L, Barrea L, Armani A, Caprio M · Healthcare (Basel, Switzerland) · 2022-03-19

Randomized clinical trial

18. Effects of 30 days of ketogenic diet on body composition, muscle strength, muscle area, metabolism, and performance in semi-professional soccer players.

Antonio Paoli A, Mancin L, Caprio M, Monti E, Narici MV, Cenci L, Piccini F, Pincella M, Grigoletto D, Marcolin G · Journal of the International Society of Sports Nutrition · 2021-09-16

Randomized clinical trial

19. Effects of Combining a Ketogenic Diet with Resistance Training on Body Composition, Strength, and Mechanical Power in Trained Individuals: A Narrative Review.

Valenzuela PL, Castillo-García A, Lucia A, Naclerio F · Nutrients · 2021-09-01

Preclinical / mechanistic

20. Ketogenic diet with medium-chain triglycerides restores skeletal muscle function and pathology in a rat model of Duchenne muscular dystrophy.

Fujikura Y, Sugihara H, Hatakeyama M, Oishi K, Yamanouchi K · FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2021-07-16

Clinical trial / intervention

21. The ketogenic diet preserves skeletal muscle with aging in mice.

Wallace MA, Aguirre NW, Marcotte GR, Marshall AG, Baehr LM, Hughes DC, Hamilton KL, Roberts MN, Lopez-Dominguez JA, Miller BF, Ramsey JJ, Baar K · Aging cell · 2021-03-06

Randomized clinical trial

22. Effects of Two Months of Very Low Carbohydrate Ketogenic Diet on Body Composition, Muscle Strength, Muscle Area, and Blood Parameters in Competitive Natural Body Builders.

Paoli A, Cenci L, Pompei P, Sahin N, Bianco A, Neri M, Caprio M, Moro T · Nutrients · 2021-01-26

Clinical trial / intervention

23. A ketogenic diet combined with exercise alters mitochondrial function in human skeletal muscle while improving metabolic health.

Miller VJ, LaFountain RA, Barnhart E, Sapper TS, Short J, Arnold WD, Hyde PN, Crabtree CD, Kackley ML, Kraemer WJ, Villamena FA, Volek JS · American journal of physiology. Endocrinology and metabolism · 2020-09-28

Randomized clinical trial

24. Effects of a Ketogenic Diet on Muscle Fatigue in Healthy, Young, Normal-Weight Women: A Randomized Controlled Feeding Trial.

Sjödin A, Hellström F, Sehlstedt E, Svensson M, Burén J · Nutrients · 2020-03-30

Preclinical / mechanistic

25. Ketogenic diet induces skeletal muscle atrophy via reducing muscle protein synthesis and possibly activating proteolysis in mice.

Nakao R, Abe T, Yamamoto S, Oishi K · Scientific reports · 2019-12-23

Review

26. Anticatabolic Effects of Ketone Bodies in Skeletal Muscle.

Koutnik AP, D'Agostino DP, Egan B · Trends in endocrinology and metabolism: TEM · 2019-01-31

Case report / case series

27. Modified Atkins ketogenic diet improves heart and skeletal muscle function in glycogen storage disease type III.

Francini-Pesenti F, Tresso S, Vitturi N · Acta myologica : myopathies and cardiomyopathies : official journal of the Mediterranean Society of Myology · 2019-03-01

Preclinical / mechanistic

28. Short-term and long-term ketogenic diet therapy and the addition of exercise have differential impacts on metabolic gene expression in the mouse energy-consuming organs heart and skeletal muscle.

Shimizu K, Saito H, Sumi K, Sakamoto Y, Tachi Y, Iida K · Nutrition research (New York, N.Y.) · 2018-09-19

Preclinical / mechanistic

29. Ketogenic diet increases mitochondria volume in the liver and skeletal muscle without altering oxidative stress markers in rats.

Parry HA, Kephart WC, Mumford PW, Romero MA, Mobley CB, Zhang Y, Roberts MD, Kavazis AN · Heliyon · 2018-11-24

Randomized clinical trial

30. Efficacy and safety of very-low-calorie ketogenic diet: a double blind randomized crossover study.

Colica C, Merra G, Gasbarrini A, De Lorenzo A, Cioccoloni G, Gualtieri P, Perrone MA, Bernardini S, Bernardo V, Di Renzo L, Marchetti M · European review for medical and pharmacological sciences · 2017-05-25

Randomized clinical trial

31. Very-low-calorie ketogenic diet with aminoacid supplement versus very low restricted-calorie diet for preserving muscle mass during weight loss: a pilot double-blind study.

Merra G, Miranda R, Barrucco S, Gualtieri P, Mazza M, Moriconi E, Marchetti M, Chang TF, De Lorenzo A, Di Renzo L · European review for medical and pharmacological sciences · 2016-07-08

Preclinical / mechanistic

32. Lack of long-term histopathologic changes in brain and skeletal muscle of mice treated with a ketogenic diet.

Rho JM, Sarnat HB, Sullivan PG, Robbins CA, Kim DW · Journal of child neurology · 2004-11-06

Randomized clinical trial

33. Acute nutritional ketosis during early recovery from aerobic exercise does not affect skeletal muscle transcriptomic response in humans.

Mosquera-Lopez E, Louis J, Edwards JP, Pugh J, Viggars MR, Owens DJ, Areta JL · European journal of applied physiology · 2025-09-17

Review

34. Anabolic and anticatabolic actions of ketone bodies on skeletal muscle: potential relevance in the management of skeletal muscle wasting.

Churchward-Venne TA · Current opinion in clinical nutrition and metabolic care · 2025-09-03

Clinical trial / intervention

35. Anthropometric Trajectories and Dietary Compliance During a Personalized Ketogenic Program.

García-Gorrita C, Soriano JM, Merino-Torres JF, San Onofre N · Nutrients · 2025-04-27

Clinical trial / intervention

36. Combined Effects of Ketogenic Diet and Aerobic Exercise on Skeletal Muscle Fiber Remodeling and Metabolic Adaptation in Simulated Microgravity Mice.

Chen J, Li W, Yu L, Zhang B, Li Z, Zou P, Ding B, Dai X, Wang Q · Metabolites · 2025-04-13

Other

37. Impact of a Fish-Based Restrictive Ketogenic Diet on Body Composition and Strength Capacity: A Pre-Post Study.

Siedzik K, Góral K, Rodziewicz-Flis E, Olek RA, Ziółkowski W · Nutrients · 2025-04-08

Osteoarthritis Recent peer-reviewed literature

Source-audited selection from the connected PDF archive. Systematic reviews/meta-analyses and recent human evidence are prioritized when available; sparse areas are explicitly kept sparse.

Pilot interventional study · 2024

1. Efficacy, Safety, and Tolerability of a Very Low-Calorie Ketogenic Diet in Women with Obesity and Symptomatic Knee Osteoarthritis: A Pilot Interventional Study

Original publication title: Efficacy, Safety, and Tolerability of a Very Low-Calorie Ketogenic Diet in Women with Obesity and Symptomatic Knee Osteoarthritis: A Pilot Interventional Study

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Mini-review

2. The Effect of Ketogenic Diet on Inflammatory Arthritis and Cardiovascular Health in Rheumatic Conditions: A Mini Review

Original publication title: The Effect of Ketogenic Diet on Inflammatory Arthritis and Cardiovascular Health in Rheumatic Conditions: A Mini Review

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Preclinical mechanistic study

3. Ketogenic Diet Ameliorates Inflammasome Activation in Experimental Osteoarthritis

Original publication title: Ketogenic Diet Ameliorates Inflammasome Activation in Experimental Osteoarthritis

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Randomized clinical trial

4. Five-year patient-reported outcomes of individualized nutrition therapy supporting nutritional ketosis in adults with type 2 diabetes.

Adams RN, Athinarayanan SJ, Phinney SD, Volek JS, McKenzie AL · Frontiers in nutrition · 2026-08-14

Rheumatoid Arthritis Recent peer-reviewed literature

Source-audited selection from the connected PDF archive. Systematic reviews/meta-analyses and recent human evidence are prioritized when available; sparse areas are explicitly kept sparse.

Direct human study

1. Reduction in Serum Leptin and IGF-1 but Preserved T-Lymphocyte Numbers and Activation after a Ketogenic Diet in Rheumatoid Arthritis Patients

Original publication title: Reduction in Serum Leptin and IGF-1 but Preserved T-Lymphocyte Numbers and Activation after a Ketogenic Diet in Rheumatoid Arthritis Patients

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Review

2. The Effect of Ketogenic Diet on Inflammatory Arthritis and Cardiovascular Health in Rheumatic Conditions

Original publication title: The Effect of Ketogenic Diet on Inflammatory Arthritis and Cardiovascular Health in Rheumatic Conditions

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Systematic review · broader diet evidence

3. Rheumatoid Arthritis and Dietary Interventions: Systematic Review

Original publication title: Rheumatoid Arthritis and Dietary Interventions: Systematic Review

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Randomized clinical trial

4. Ketogenic diet in rheumatoid arthritis, psoriatic arthritis and psoriasis: A scoping review of clinical and mechanistic evidence.

Conforti A, Russo V, Lucchetti L, Fiorino E, Messina F, Francomano D, Merendino N, Marchetti M · Autoimmunity reviews · 2026-07-15

Randomized clinical trial

5. Serum levels of interleukin-6 and dehydroepiandrosterone sulphate in response to either fasting or a ketogenic diet in rheumatoid arthritis patients.

Fraser DA, Thoen J, Djøseland O, Førre O, Kjeldsen-Kragh J · Clinical and experimental rheumatology · 2000-07-15

Fibromyalgia Recent peer-reviewed literature

Source-audited selection from the connected PDF archive. Systematic reviews/meta-analyses and recent human evidence are prioritized when available; sparse areas are explicitly kept sparse.

Clinical follow-up · 2024

1. The Effectiveness of the Low-Glycemic and Insulinemic (LOGI) Regimen in Maintaining the Benefits of the VLCKD in Fibromyalgia Patients

Original publication title: The Effectiveness of the Low-Glycemic and Insulinemic (LOGI) Regimen in Maintaining the Benefits of the VLCKD in Fibromyalgia Patients

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Human clinical study

2. Efficacy, Safety and Tolerability of VLCKD in Women with Obesity and Fibromyalgia

Original publication title: Efficacy, Safety and Tolerability of VLCKD in Women with Obesity and Fibromyalgia

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Systematic review · broader diet evidence

3. Dietary Interventions in Fibromyalgia: A Systematic Review

Original publication title: Dietary Interventions in Fibromyalgia: A Systematic Review

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Clinical trial / intervention

4. Efficacy, safety and tolerability of very low-calorie ketogenic diet in obese women with fibromyalgia: a pilot interventional study.

Ciaffi J, Lisi L, Mari A, Mancarella L, Brusi V, Pignatti F, Ricci S, Vitali G, Stefanelli N, Assirelli E, Neri S, Naldi S, Faldini C, Ursini F · Frontiers in nutrition · 2023-07-12

Dermatology & Immunometabolism

Acne Recent peer-reviewed literature

Direct ketogenic evidence for acne is still limited. The section therefore includes the acne-specific VLCKD paper first, followed by dermatology reviews that explicitly discuss acne and ketogenic/low-glycemic mechanisms.

Direct acne-focused review

1. Very low-calorie ketogenic diet (VLCKD): a therapeutic nutritional tool for acne

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Clinical review including acne · 2024

2. Impact of Ketogenic and Low-Glycemic Diets on Inflammatory Skin Conditions

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Recent dermatology review · 2025

3. Effects of the ketogenic diet on skin—potential benefits and risks

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Dermatology review

4. The Ketogenic Diet and Dermatology

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Dermatology review

5. Ketones, the ketogenic diet, and the skin: a review of where we are and where we should go

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Human pilot study

6. Very Low-Calorie Ketogenic Diet (VLCKD) in the Management of Hidradenitis Suppurativa (Acne Inversa): An Effective and Safe Tool for Improvement of the Clinical Severity of Disease. Results of a Pilot Study

Original publication title: Very Low-Calorie Ketogenic Diet (VLCKD) in the Management of Hidradenitis Suppurativa (Acne Inversa): An Effective and Safe Tool for Improvement of the Clinical Severity of Disease. Results of a Pilot Study

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Review

7. The effect of the ketogenic diet on Acne: Could it be a therapeutic tool?

Barrea L, Cacciapuoti S, Megna M, Verde L, Marasca C, Vono R, Camajani E, Colao A, Savastano S, Fabbrocini G, Muscogiuri G · Critical reviews in food science and nutrition · 2023-02-13

Clinical trial / intervention

8. Ketogenic Diet and the Skin.

Harb D, Abdullah L, Kurban M, Abbas O · Skinmed · 2023-11-10

Clinical trial / intervention

9. Consuming an All-Meat Ketogenic Diet for the Long-Term Management of Candida Vulvovaginitis and Vaginal Hidradenitis Suppurativa: A 47-Month Follow-Up Case Report.

Yar N, Mukona LT, Nguyen K, Nalbandyan L, Mukona L, St Fleur G, Lamberty NL, Zullo K, Le A, Van A, Allen B · Cureus · 2022-10-20

Review

10. Nutrition and acne: therapeutic potential of ketogenic diets.

Paoli A, Grimaldi K, Toniolo L, Canato M, Bianco A, Fratter A · Skin pharmacology and physiology · 2012-02-11

Psoriasis Recent peer-reviewed literature

Direct ketogenic evidence for psoriasis remains limited. Human clinical evidence is placed before broader reviews and preclinical work.

Human comparative study

1. The Effect of a Ketogenic Diet versus Mediterranean Diet on Clinical and Biochemical Markers of Inflammation in Patients with Obesity and Psoriatic Arthritis

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Clinical review · 2024

2. Impact of Ketogenic and Low-Glycemic Diets on Inflammatory Skin Conditions

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Recent clinical report · 2025

3. A Multimodal Approach to Managing Severe Psoriasis Vulgaris

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Preclinical/mechanistic study

4. The Influence of Ketogenic Diets on Psoriasiform-Like Skin Inflammation

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Randomized clinical trial

5. Ketogenic diet in rheumatoid arthritis, psoriatic arthritis and psoriasis: A scoping review of clinical and mechanistic evidence.

Conforti A, Russo V, Lucchetti L, Fiorino E, Messina F, Francomano D, Merendino N, Marchetti M · Autoimmunity reviews · 2026-07-15

Other

6. Correction: Ketogenic diet improves disease activity and cardiovascular risk in psoriatic arthritis: A proof of concept study.

Ramonda R, Ometto F, Striani G, Cozzi G, Basso D, Evangelista F, Lorenzin M, Scagnellato L, Aita A, Favero M, Brocadello F, Doria A · PloS one · 2026-03-06

Randomized clinical trial

7. The Effect of a Ketogenic Diet versus Mediterranean Diet on Clinical and Biochemical Markers of Inflammation in Patients with Obesity and Psoriatic Arthritis: A Randomized Crossover Trial.

Lambadiari V, Katsimbri P, Kountouri A, Korakas E, Papathanasi A, Maratou E, Pavlidis G, Pliouta L, Ikonomidis I, Malisova S, Vlachos D, Papadavid E · International journal of molecular sciences · 2024-02-20

Clinical trial / intervention

8. Ketogenic Diet and the Skin.

Harb D, Abdullah L, Kurban M, Abbas O · Skinmed · 2023-11-10

Randomized clinical trial

9. Clinical and nutritional management of very-low-calorie ketogenic diet (VLCKD) in patients with psoriasis and obesity: a practical guide for the nutritionist.

Barrea L, Caprio M, Camajani E, Verde L, Elce A, Frias-Toral E, Ceriani F, Cucalón G, Garcia-Velasquez E, El Ghoch M, Colao A, Savastano S, Muscogiuri G · Critical reviews in food science and nutrition · 2022-06-02

Review

10. Very low-calorie ketogenic diet (VLCKD) in patients with psoriasis and obesity: an update for dermatologists and nutritionists.

Barrea L, Megna M, Cacciapuoti S, Frias-Toral E, Fabbrocini G, Savastano S, Colao A, Muscogiuri G · Critical reviews in food science and nutrition · 2020-09-24

Case report / case series

11. A case of prurigo pigmentosa occurring in a patient with psoriasis vulgaris following a ketogenic diet during the COVID-19 pandemic.

Oku A, Nakai K, Tsuruta D · International journal of dermatology · 2021-08-07

Other

12. Effect of Very-Low-Calorie Ketogenic Diet on Psoriasis Patients: A Nuclear Magnetic Resonance-Based Metabolomic Study.

Castaldo G, Pagano I, Grimaldi M, Marino C, Molettieri P, Santoro A, Stillitano I, Romano R, Montoro P, D'Ursi AM, Rastrelli L · Journal of proteome research · 2020-11-09

Clinical trial / intervention

13. Aggressive weight-loss program with a ketogenic induction phase for the treatment of chronic plaque psoriasis: A proof-of-concept, single-arm, open-label clinical trial.

Castaldo G, Rastrelli L, Galdo G, Molettieri P, Rotondi Aufiero F, Cereda E · Nutrition (Burbank, Los Angeles County, Calif.) · 2020-02-05

Clinical trial / intervention

14. Very low-calorie ketogenic diet may allow restoring response to systemic therapy in relapsing plaque psoriasis.

Castaldo G, Galdo G, Rotondi Aufiero F, Cereda E · Obesity research & clinical practice · 2015-11-11

Keto Rash / Prurigo Pigmentosa Recent peer-reviewed literature

Source-audited selection from the connected PDF archive. Systematic reviews/meta-analyses and recent human evidence are prioritized when available; sparse areas are explicitly kept sparse.

Recent review · 2026

1. Prurigo Pigmentosa: An Increasingly Diagnosed Dermatological Condition Associated with Ketosis

Original publication title: Prurigo Pigmentosa: An Increasingly Diagnosed Dermatological Condition Associated with Ketosis

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Case report · 2026

2. Atypical Prurigo Pigmentosa Following Ketogenic Diet: Successful Treatment with Doxycycline and Tofacitinib

Original publication title: Atypical Prurigo Pigmentosa Following Ketogenic Diet: Successful Treatment with Doxycycline and Tofacitinib

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Case series · 2026

3. Clinical and Histopathological Characteristics of Prurigo Pigmentosa: A Case Series

Original publication title: Clinical and Histopathological Characteristics of Prurigo Pigmentosa: A Case Series

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Review · 2026

4. Prurigo Pigmentosa Following Bariatric Surgery: A Comprehensive Review

Original publication title: Prurigo Pigmentosa Following Bariatric Surgery: A Comprehensive Review

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Review · 2025

5. Effects of the Ketogenic Diet on Skin—Potential Benefits and Risks

Original publication title: Effects of the Ketogenic Diet on Skin—Potential Benefits and Risks

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Review · 2025

6. Prurigo Pigmentosa: Review of the Literature

Original publication title: Prurigo Pigmentosa: Review of the Literature

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Case report

7. Prurigo Pigmentosa Associated with a Ketogenic Diet

Original publication title: Prurigo Pigmentosa Associated with a Ketogenic Diet

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Case report

8. Remission of Prurigo Pigmentosa after Breaking Ketogenic Diet

Original publication title: Remission of Prurigo Pigmentosa after Breaking Ketogenic Diet

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Case report

9. A Rare Case of Prurigo Pigmentosa in a Danish Couple

Original publication title: A Rare Case of Prurigo Pigmentosa in a Danish Couple

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Review

10. Prurigo Pigmentosa - an increasingly diagnosed dermatological condition associated with ketogenic diet.

Aliu A, Vidakovic M, Krauß M, Hyun J, Oellig F, Gambichler T, Müller VL, Kreuter A · Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG · 2026-06-14

Other

11. Prurigo Pigmentosa Associated With Ketogenic Diet.

Blaya Imbernón D, Finello M, Diez Recio E · JAMA dermatology · 2026-05-13

Other

12. Unexpected journey with the ketogenic diet: a patient's experience with prurigo pigmentosa.

Liu ZH · Clinical and experimental dermatology · 2024-04-14

Case report / case series

13. Prurigo Pigmentosa Induced by a Ketogenic Diet.

Nellore A, Maher E, Abate M · Cureus · 2023-05-25

Case report / case series

14. Remission of Prurigo Pigmentosa after Breaking Ketogenic Diet and Resuming Regular Diet.

Daneshpazhooh M, Nikyar Z, Kamyab Hesari K, Rostami E, Taraz Jamshidi S, Mohaghegh F · Advanced biomedical research · 2022-08-30

Review

15. Ketogenic diet-induced prurigo pigmentosa: a rising association.

Shahrigharahkoshan S, AlHalees Z, Pehr K · International journal of dermatology · 2021-11-26

Case report / case series

16. Prurigo pigmentosa following a ketogenic diet: a case report.

Sun HY, Sebaratnam DF · European journal of clinical nutrition · 2021-07-23

Case report / case series

17. Ketogenic Diet-induced Prurigo Pigmentosa (the "Keto Rash"): A Case Report and Literature Review.

Xiao A, Kopelman H, Shitabata P, Nami N · The Journal of clinical and aesthetic dermatology · 2022-03-16

Case report / case series

18. A case of prurigo pigmentosa occurring in a patient with psoriasis vulgaris following a ketogenic diet during the COVID-19 pandemic.

Oku A, Nakai K, Tsuruta D · International journal of dermatology · 2021-08-07

Case report / case series

19. Prurigo Pigmentosa Following Ketogenic Diet.

Ben Hamouda M, Ghariani Fetoui N, Ghariani N, Boussofara L, Denguezli M · The American journal of medicine · 2020-11-11

Other

20. Bullous prurigo pigmentosa following a ketogenic diet.

Mao DD, Chen X, Zhang H, Jin J, Chen X, Wen GD · Chinese medical journal · 2021-01-05

Case report / case series

21. A unique case of prurigo pigmentosa related to ketogenic diet.

Lonowski S, Levins P · Dermatology online journal · 2020-02-15

Case report / case series

22. Prurigo pigmentosa following ketogenic diet and bariatric surgery: A growing association.

Alshaya MA, Turkmani MG, Alissa AM · JAAD case reports · 2019-06-08

Case report / case series

23. Prurigo pigmentosa after a strict ketogenic diet.

Michaels JD, Hoss E, DiCaudo DJ, Price H · Pediatric dermatology · 2013-12-30

Other

24. Prurigo Pigmentosa After Ketogenic Diet.

Shao Y, Zhang H · Journal of cutaneous medicine and surgery · 2025-05-24

Review

25. Prurigo Pigmentosa: Review of the Literature, Impact of Ketogenic Diets and Proposal of a Hypothesis.

Demircioğlu D, Durmaz EÖ, Demirkesen C, Şahin S · Indian journal of dermatology · 2025-05-08

Case report / case series

26. Prurigo pigmentosa related to a popular diet trend: the ketogenic diet.

Barrabés-Torrella C, Iglesias-Plaza A, Fernández-Figueras MT, Salleras-Redonnet M · Anais brasileiros de dermatologia · 2025-01-06

Case report / case series

27. Prurigo Pigmentosa Associated with a Ketogenic Diet in a Romanian Patient: A Case Report.

Iliescu CA, Beiu C, Tebeică T, Popa LG · Healthcare (Basel, Switzerland) · 2025-02-02

Asthma Recent peer-reviewed literature

Source-audited selection from the connected PDF archive. Systematic reviews/meta-analyses and recent human evidence are prioritized when available; sparse areas are explicitly kept sparse.

Case report · 2023

1. Alleviation of Asthma Symptoms After Ketogenic Diet: A Case Report

Original publication title: Alleviation of Asthma Symptoms After Ketogenic Diet: A Case Report

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Review

2. [Effect of ketogenic diet on obesity asthma].

Kong LD, Wu QP · Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases · 2022-02-09

Review

3. The Role of Short-Chain Fatty Acids in the Interplay between a Very Low-Calorie Ketogenic Diet and the Infant Gut Microbiota and Its Therapeutic Implications for Reducing Asthma.

Alsharairi NA · International journal of molecular sciences · 2020-12-16

Inflammation & Immunometabolism Recent peer-reviewed literature

Source-audited selection from the connected PDF archive. Systematic reviews/meta-analyses and recent human evidence are prioritized when available; sparse areas are explicitly kept sparse.

Recent review · 2026

1. The Value of Targeting Ketone Body Metabolism in Inflammatory and Autoimmune Diseases

Original publication title: The Value of Targeting Ketone Body Metabolism in Inflammatory and Autoimmune Diseases

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Mechanistic study · 2025

2. SIRT3 Is Required for the Protective Function of Ketogenic Diet on Neural Inflammation and Neuropathic Pain

Original publication title: SIRT3 Is Required for the Protective Function of Ketogenic Diet on Neural Inflammation and Neuropathic Pain

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Human clinical study

3. Weight Loss, Changes in Body Composition and Inflammatory Status after a Very Low-Energy Ketogenic Therapy

Original publication title: Weight Loss, Changes in Body Composition and Inflammatory Status after a Very Low-Energy Ketogenic Therapy

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Review

4. Exploring the Ketogenic Diet's Potential in Reducing Neuroinflammation and Modulating Immune Responses

Original publication title: Exploring the Ketogenic Diet's Potential in Reducing Neuroinflammation and Modulating Immune Responses

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Review / mechanistic evidence

5. Impact of Fasting and Ketogenic Interventions on the NLRP3 Inflammasome

Original publication title: Impact of Fasting and Ketogenic Interventions on the NLRP3 Inflammasome

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Preclinical immunometabolic study

6. Ketogenic Diet Protects from Experimental Colitis in a Mouse Model Regardless of Dietary Fat Source

Original publication title: Ketogenic Diet Protects from Experimental Colitis in a Mouse Model Regardless of Dietary Fat Source

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Human / clinical or translational evidence

7. Metabolic Effects of Ketogenic Diets: Whole-Body Metabolism, Adipose Tissue and Metabolic Organs

Original publication title: Metabolic Effects of Ketogenic Diets: Whole-Body Metabolism, Adipose Tissue and Metabolic Organs

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Human / clinical or translational evidence

8. Persistent Inflammation, Immunosuppression, and Catabolism in Metabolic Disease

Original publication title: Persistent Inflammation, Immunosuppression, and Catabolism in Metabolic Disease

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Human / clinical or translational evidence

9. Ketogenic Diet Inhibits Neointimal Hyperplasia by Suppressing Oxidative Stress and Inflammation

Original publication title: Ketogenic Diet Inhibits Neointimal Hyperplasia by Suppressing Oxidative Stress and Inflammation

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Human pilot study

10. Very Low-Calorie Ketogenic Diet (VLCKD) in the Management of Hidradenitis Suppurativa (Acne Inversa): An Effective and Safe Tool for Improvement of the Clinical Severity of Disease. Results of a Pilot Study

Original publication title: Very Low-Calorie Ketogenic Diet (VLCKD) in the Management of Hidradenitis Suppurativa (Acne Inversa): An Effective and Safe Tool for Improvement of the Clinical Severity of Disease. Results of a Pilot Study

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Mechanistic cell study

11. The Ketogenic Diet and Neuroinflammation: The Action of Beta-Hydroxybutyrate in a Microglial Cell Line

Original publication title: The Ketogenic Diet and Neuroinflammation: The Action of Beta-Hydroxybutyrate in a Microglial Cell Line

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Mechanistic review

12. Effects of Ketogenic Diet on Neuroinflammation in Neurodegenerative Diseases

Original publication title: Effects of Ketogenic Diet on Neuroinflammation in Neurodegenerative Diseases

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Human immunometabolic evidence

13. Immunomodulatory Effect of a Very-Low-Calorie Ketogenic Diet

Original publication title: Immunomodulatory Effect of a Very-Low-Calorie Ketogenic Diet

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Preclinical / mechanistic

14. Ketone ester alleviates sepsis-associated liver injury through β-hydroxybutyrylation of STAT1.

Bai Y, Li K, Zhu D, Li R, Yan Y, Zhong C, Zha L, Wang Q · Immunobiology · 2026-09-11

Clinical trial / intervention

15. Ketogenic diet-induced changes in hepatic drug metabolism with potential implications for ozanimod pharmacokinetics in mice.

Frybortova V, Satka S, Jourova L, Anzenbacher P, Zapletalova I, Kraus M, Kostovcikova K, Kverka M, Anzenbacherova E · PloS one · 2026-09-08

Review

16. [Research progress on the role and mechanism of ketogenic diet in regulating gametogenesis].

Zhang T, Cao C, Pang W · Sheng wu gong cheng xue bao = Chinese journal of biotechnology · 2026-08-25

Systematic review / meta-analysis

17. Effects of the Mediterranean Diet, Ketogenic Diet, and Intermittent Fasting on Iron Metabolism and Iron Deficiency Risk in Adults with Obesity: A Systematic Literature Review.

La Vignera S, Condorelli R · Nutrients · 2026-08-17

Preclinical / mechanistic

18. Rehmannia glutinosa Extracts Enhances Ketone Bodies Expression and Alleviates Ulcerative Colitis as A Novel Ketogenic Functional Food.

Gao Y, Wang S, Yang Y, Tang W, Zhen J, Song X · Food science & nutrition · 2026-08-16

Case report / case series

19. Early-Onset Euglycemic Diabetic Ketoacidosis Following Empagliflozin Initiation Triggered by Acute Influenza and a Ketogenic Diet.

Meyer MS, Ramesh S, Rammouni Y, Lasry S, Sawan H, Zakaria K · Cureus · 2026-08-09

Review

20. Ketogenic diet and Parkinson's disease.

Ye Y, Li S, Chen T · Frontiers in molecular neuroscience · 2026-08-05

Randomized clinical trial

21. The Ketogenic Diet in the Prevention and Treatment of Hypertension (HTN).

Rodzeń Ł, Dyńka D, Rodzeń M, Karakuła-Juchnowicz H, Łojko D, Kraszewski S, Grzywacz Ż, Bikman B, Unwin J, Unwin D, Fazio S · Biomedicines · 2026-07-31

Randomized clinical trial

22. Ketogenic diet in rheumatoid arthritis, psoriatic arthritis and psoriasis: A scoping review of clinical and mechanistic evidence.

Conforti A, Russo V, Lucchetti L, Fiorino E, Messina F, Francomano D, Merendino N, Marchetti M · Autoimmunity reviews · 2026-07-15

Clinical trial / intervention

23. Ketogenic Diet-Mediated Immunomodulation for Prevention of Epilepsia Partialis Continua in Rasmussen's Encephalitis: Review and Case Study.

Salgado Rueda SA, Moreno Guerra N, Vargas Rojas JL · Case reports in neurology · 2026-07-10

Clinical trial / intervention

24. The Ketogenic Diet: A Possible Intervention for Improving Hippocampal Function in Neurological Disorders.

Jahanmehr D, Ahmadi A, Fadaei M, Sangi Nasab Lahijan A, Shafiee Sabet M, Kalantari Dehaghi H, Asadi-Golshan R · Nutrition reviews · 2026-07-10

Randomized clinical trial

25. Very-Low-Energy Ketogenic Therapy Modulates the Metabolic-Antioxidant Axis in Patients with Obesity and Type 2 Diabetes: A Non-Randomized Clinical Trial.

Tini S, Celano S, Pigni S, De Palma E, Ozdemir HI, Raiteri T, Antonioli A, Baima J, Antoniotti V, Caputo M, Marzullo P, Prodam F · Antioxidants (Basel, Switzerland) · 2026-07-04

Clinical trial / intervention

26. Ketogenic diet alleviates acute radiation-induced intestinal injury through JAK2/STAT3/RORγt/IL-17A signaling pathway via gut microbiome.

Yang J, Ling Z, Zhou M, Tao M, Mao J, Guo H, Wang J, Qu X, Wang Y, Zhu Y, Zhang K, Yan X · Communications biology · 2026-06-30

Systematic review / meta-analysis

27. The impact of the ketogenic diet on the health of patients with metabolic syndrome: a scoping review.

Winiarska M, Wiśniewska D, Klimas M, Jucha D, Szczupak M, Kobak J, Krupa-Nurcek S · Frontiers in nutrition · 2026-06-29

Randomized clinical trial

28. A fat chance at neuroprotection: Ketogenic diet and Parkinson's disease.

Hitawala G, Shulman LM · Clinical nutrition ESPEN · 2026-06-25

Other

29. Ketogenic Diet Alleviates Colorectal Cancer by Attenuating Macrophage M2 Polarisation Triggered by Oncometabolite MMA Derived From the Gut Microbiota.

Lu Y, Shi B, Chen J, Yao H, Mi X, Shao M, Zhao Y, Meng L, Tai Q, Chen J, Shi X, Zhou D, Yao Y, He S · Cell proliferation · 2026-06-17

Randomized clinical trial

30. Ketogenic Diet for Intensive Care Patients: A Scoping Review.

Bryła J, Szczupak M, Krupa-Nurcek S · Nutrients · 2026-06-16

Review

31. Prurigo Pigmentosa - an increasingly diagnosed dermatological condition associated with ketogenic diet.

Aliu A, Vidakovic M, Krauß M, Hyun J, Oellig F, Gambichler T, Müller VL, Kreuter A · Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG · 2026-06-14

Clinical trial / intervention

32. Ketogenic Diet and β-Hydroxybutyrate Suppress Bladder Cancer Growth and Enhance Anti-PD-L1 Immunotherapy Efficacy.

Zeng Y, Gu G, Yang L, Fan B, Cui H, Yan L, Liu Z · Cancer science · 2026-06-11

Case report / case series

33. Ketogenic diet therapy for epilepsy in conjunction with concurrent inflammatory bowel disease: Case series and recommendations.

Kossoff EH, Bessone SK, Chatfield B, Jerger L, Madsen S, Parrish T, Turner Z, Vanatta L, Worden LT · Epilepsy research · 2026-05-31

Randomized clinical trial

34. Feasibility and Safety of a Ketogenic Diet During Systemic Therapy for Metastatic Renal Cell Carcinoma: Results from the Cetorein Pilot Study.

Rolley C, Zidane M, Nedelcu C, Barth M, Saulnier P, Procaccio V, Bigot P · Nutrients · 2026-05-27

Clinical trial / intervention

35. The Ketogenic Diet Fails to Mitigate Seizures and Neuroinflammatory Responses in a Mouse Model of Virus-Induced Epilepsy.

Meili CH, Allen K, Doty DJ, Del Fiol S, DePaula-Silva AB · bioRxiv : the preprint server for biology · 2026-05-21

Preclinical / mechanistic

36. Ketogenic diet improves motor and anxiety-like behaviors plus cerebellar inflammation via axonal remyelination in the BTBR mouse model of autism.

Alò R, Olivito I, Minervini D, Avolio E, De Bartolo A, Perrotta I, Cerra MC, Angelone T, Rocca C, Facciolo RM · The Journal of nutritional biochemistry · 2026-05-15

Randomized clinical trial

37. Ketogenic Diet-Based Therapy for Fatigue in Patients with Multiple Sclerosis.

Filippi F, Lorenzut S, Garbo R, Lamon E, Del Negro I, Nilo A, Pez S, Gigli GL, Valente M · Nutrients · 2026-05-08

Randomized clinical trial

38. The ketogenic diet alleviates autoimmune thyroiditis caused by Th17/Treg imbalance by inhibiting the HMGB1/NLRP3 signaling pathway.

Luo Y, Gao H, Wang M, Wang Z, Jin Z, Song N, Liu Z, Yang X · PloS one · 2026-05-08

Systematic review / meta-analysis

39. Fueling failure or fostering fusion? A critical review of the potential effect of ketogenic, intermittent fasting, and low-carbohydrate diets on dental implant osseointegration.

Alshahrani FA, Taymour N · The Saudi dental journal · 2026-05-02

Clinical trial / intervention

40. Macronutrient Composition and Genetic Background Determine the Response to a Ketogenic Diet.

Zhang Z, Moura-Assis A, Liu S, Millet A, Shaked J, Rajan D, Alwaseem H, Viscio MI, Molina H, Birsoy K, Friedman J · bioRxiv : the preprint server for biology · 2026-04-27

Clinical trial / intervention

41. Ketogenic metabolic therapy: low-carbohydrate interventions as novel neuroprotective strategies for cognitive dysfunction in diabetes.

Xun Y, Zeng W · Frontiers in aging neuroscience · 2026-04-24

Clinical trial / intervention

42. Ketogenic diet modulates gut microbiota composition in an experimental model of cerebral palsy.

Dantas Alves JS, De Oliveira Melo NC, Toscano AE, Manhães-De-Castro R, Fraga Filho CX, Cruz Neto JPR, De Brito Alves JL, Muniz GS · Nutritional neuroscience · 2026-04-24

Preclinical / mechanistic

43. Ketogenic diet exacerbates DSS-induced colitis through a β-hydroxybutyrate-Thomasclavelia spiroformis-γδ17 T cell axis in mice.

Liu Y, Wu X, Chen L, Wang S, Xu J, Wang W, Yao X, Xie W, Zhong X, Li S, Li Y, Han L, Xie C, Chen L, Gonzalez FJ, Liu W · Nature communications · 2026-04-23

Clinical trial / intervention

44. Ketone ester supplementation in aged mice reduces activation of B cell subsets.

Adkisson-Floro A, Tiwari R, Nomura M, Riley RR, Kwok R, Sellegounder D, Khalid MM, Kasler HG, Newman JC, Verdin E · bioRxiv : the preprint server for biology · 2026-04-22

Clinical trial / intervention

45. The Role of the Ketogenic Diet in Lung Cancer: Current Evidence and Future Perspectives.

Eleftheriadou ED, Kotoulas SC, Grammatikopoulou MG, Karakousi A, Maria A, Trimpali A, Tsalampounis X, Evangelidis P, Vamvakis A, Pataka A, Spyratos D · Cancers · 2026-04-17

Other

46. Chrysin attenuates tramadol-driven renal dysfunction via regulation of RNA networks, antioxidant pathways, and ketogenic metabolism.

Öz MA, Kandemir Ö, Özdemir S, Şimşek H, Küçükler S, Yazıcı R, Mutlu H, Kandemir FM · European journal of pharmacology · 2026-04-17

Randomized clinical trial

47. Impact of a ketogenic diet on clinical outcomes and immunological markers in myasthenia gravis: A randomized pilot study.

Makus B, Schulze D, Lehnerer S, Gerischer L, Stein M, Doksani P, Dusemund C, Hoffmann S, Meisel A, Stascheit F · Journal of autoimmunity · 2026-04-17

Other

48. Ketogenic diet synergistic reprogramming of both host and microbiome promotes tissue regeneration.

Nagai M, Band V, Chi L, Smelkinson M, Schwarz B, Brandes NT, Burns A, Perez-Chaparro PJ, McCauley KE, Corral D, Bouladoux N, Link VM, Zheng L, Constantinides MG, Otto M, Moutsopoulos NM, Belkaid Y · bioRxiv : the preprint server for biology · 2026-04-13

Clinical trial / intervention

49. Designing Nutrition Studies for Long COVID and Related Infection-Associated Chronic Illness: Qualitative Insights From a Patient-Reported Evaluation of Ketogenic Metabolic Therapy.

Colgan DD, Buttolph L, Grow T, Stadler DD, Ruddick M, Davenport TE, Zwickey H · Journal of patient experience · 2026-04-13

Clinical trial / intervention

50. Ketogenic interventions enhance REM sleep in females and support memory in aged rats.

Lark ARS, Mir FA, Ambareen N, Tian F, Carpenter AH, Crowley EA, Toro BA, Syme CE, Aygar S, Thendral A, Smith K, White CG, Mahamdeh MS, Choi J, Nehs CJ · Frontiers in aging neuroscience · 2026-04-10

Clinical trial / intervention

51. Ketogenic Diet: A Metabolic Key to Overcoming Cancer Therapy Resistance.

Sulaiman SH, Omer RA, Barzani KIS, Jawhar ZH, Barzani HAH · Molecular nutrition & food research · 2026-03-29

Observational human study

52. Challenges in epilepsy management in the Eastern Mediterranean (Part I): Disparities in pharmacological treatment and ketogenic diet access.

Shaaban S, Al-Ramadhani R, Alkalbani L, Kurdi D, Almasaad B, Tilako A, Dhia RB, Nderbe Melom C, Al Shehhi W, AlKhaja M, Albastaki HAK, Abdulrahman A, Ibrahim A, Benkirane N, Mohsen S · Epileptic disorders : international epilepsy journal with videotape · 2026-03-27

Clinical trial / intervention

53. Ketogenic diet attenuates late gestational sleep deprivation-induced aggression in adult offspring mice.

Zhou F, Yu X, Gong M, Yin X, Li Y, Sang Y, Liu X, Liu Y, Yan S, Song L, Zhao Y, Shi H · Physiology & behavior · 2026-03-26

Preclinical / mechanistic

54. A KETOGENIC DIET PROMOTES BLOOD-SPINAL CORD BARRIER RESEALING TO DECREASE SPINAL CORD IMMUNE CELL INFILTRATION IN A PRECLINICAL MODEL OF MULTIPLE SCLEROSIS.

Plafker KS, Walton DA, Pezant N, Plafker SM · bioRxiv : the preprint server for biology · 2026-03-24

Randomized clinical trial

55. Long-Term Fructose Intake Induces Moderate Liver Inflammation but Does not Overlap with the Detrimental Effects of the Ketogenic Diet on Hepatic Steatosis in Rats.

de Souza JG, Gurgel GG, Rodrigues FM, Braga RAM, Soares RAM, Lage LAPC, Soares IC, Levy D, Damasceno NRT · Inflammation · 2026-03-23

Randomized clinical trial

56. Immune-modulating effects of energy-restricted ketogenic diet in women with overweight and obesity: KETO-MINOX study.

Drabińska-Fois N, Ogrodowczyk AM, Bauer W, Topolska J, Bączek N, Stenbäck V, Herzig KH, Borowicz-Skoneczny S, Romaszko J · European journal of nutrition · 2026-03-07

Case report / case series

57. Ketogenic Diet as an Epigenetic Therapy in SETD1B-Related Epilepsy.

Tsang E, Gloss BS, Hayes JP, Holland AJA, Menezes MP, Branson JA, Mohammad SS, Yan JJ, Patel S, Han VX, Dale RC · Annals of clinical and translational neurology · 2026-02-19

Observational human study

58. Efficacy differences between tocilizumab and ketogenic diet during acute phase of febrile Infection-Related epilepsy syndrome in children: A retrospective cohort study.

Yan X, He J, Cheng M, Hong S, Jiang L, Han W · Epilepsy & behavior : E&B · 2026-02-02

Clinical trial / intervention

59. Sex-dependent protective effects of a ketogenic diet following prenatal stress exposure: Evidence from adolescent rats.

Begni V, Marchesin A, Orso R, Creutzberg KC, Precetti F, Cattaneo A, Riva MA · Brain, behavior, and immunity · 2026-01-19

Preclinical / mechanistic

60. A2 astrocyte polarization mediates ketogenic diet protection of blood-central nervous system barriers in experimental autoimmune encephalomyelitis.

Zhang Q, Zheng M, Siebert HC, Wang Q, Zhang R, Zhang N · Neural regeneration research · 2025-12-30

Clinical trial / intervention

61. Ketogenic Diet and Exercise Improve Peripheral Neuropathy in a Mouse Model of Metabolic Syndrome.

Eid SA, Jaisil P, Guo K, Hayes JM, Pacut C, Rigan DM, Carter A, Teener SJ, Kim B, Kiriluk C, Lentz W, Miller CM, Webber-Davis I, McQuown H, Jang DG, Patterson A, Koubek EJ, Bridges D, Hur J, Meyer JD, Feldman EL · Diabetes · 2025-11-07

Clinical trial / intervention

62. Ketogenic diet modulates immune cell transcriptional landscape and ameliorates experimental autoimmune uveitis in mice.

Duan R, Wang T, Li Z, Jiang L, Yu X, He D, Tao T, Liu X, Huang Z, Feng L, Su W · Journal of neuroinflammation · 2024-12-03

Systematic review / meta-analysis

63. Does the Ketogenic Diet Mediate Inflammation Markers in Obese and Overweight Adults? A Systematic Review and Meta-Analysis of Randomized Clinical Trials.

Rondanelli M, Gasparri C, Pirola M, Barrile GC, Moroni A, Sajoux I, Perna S · Nutrients · 2024-11-22

Clinical trial / intervention

64. Ketogenic Diet and Neuroinflammation: Implications for Neuroimmunometabolism and Therapeutic Approaches to Refractory Epilepsy.

Guerreiro D, Almeida A, Ramalho R · Nutrients · 2024-11-22

Review

65. Overcoming immunosuppression in cancer: how ketogenic diets boost immune checkpoint blockade.

Stefan VE, Weber DD, Lang R, Kofler B · Cancer immunology, immunotherapy : CII · 2024-11-13

Clinical trial / intervention

66. Weight loss, changes in body composition and inflammatory status after a very low-energy ketogenic therapy (VLEKT): does gender matter?

Muscogiuri G, Verde L, Frias-Toral E, Reytor-González C, Annunziata G, Proganò M, Savastano S, Simancas-Racines D, Colao A, Barrea L · Journal of translational medicine · 2024-10-19

Case report / case series

67. Case report: Carnivore-ketogenic diet for the treatment of inflammatory bowel disease: a case series of 10 patients.

Norwitz NG, Soto-Mota A · Frontiers in nutrition · 2024-09-02

Preclinical / mechanistic

68. Differences in the Effect of Beta-Hydroxybutyrate on the Mitochondrial Biogenesis, Oxidative Stress and Inflammation Markers in Tissues from Young and Old Rats.

Nesterova VV, Babenkova PI, Brezgunova AA, Samoylova NA, Sadovnikova IS, Semenovich DS, Andrianova NV, Gureev AP, Plotnikov EY · Biochemistry. Biokhimiia · 2024-09-02

Other

69. From tofu to T-bones: how vegan and ketogenic diets shape our immune defenses.

Morowitz MJ · Journal of leukocyte biology · 2024-02-19

Clinical trial / intervention

70. Inflammation and oxidative stress in epileptic children: from molecular mechanisms to clinical application of ketogenic diet.

Ildarabadi A, Mir Mohammad Ali SN, Rahmani F, Mosavari N, Pourbakhtyaran E, Rezaei N · Reviews in the neurosciences · 2024-02-14

Other

71. Author Correction: Differential peripheral immune signatures elicited by vegan versus ketogenic diets in humans.

Link VM, Subramanian P, Cheung F, Han KL, Stacy A, Chi L, Sellers BA, Koroleva G, Courville AB, Mistry S, Burns A, Apps R, Hall KD, Belkaid Y · Nature medicine · 2024-02-27

Clinical trial / intervention

72. Ketogenic Diet Alters the Epigenetic and Immune Landscape of Prostate Cancer to Overcome Resistance to Immune Checkpoint Blockade Therapy.

Murphy S, Rahmy S, Gan D, Liu G, Zhu Y, Manyak M, Duong L, He J, Schofield JH, Schafer ZT, Li J, Lu X, Lu X · Cancer research · 2023-09-08

Clinical trial / intervention

73. Ketogenic Diet Induced Shifts in the Gut Microbiome Associate with Changes to Inflammatory Cytokines and Brain-Related miRNAs in Children with Autism Spectrum Disorder.

Allan NP, Yamamoto BY, Kunihiro BP, Nunokawa CKL, Rubas NC, Wells RK, Umeda L, Phankitnirundorn K, Torres A, Peres R, Takahashi E, Maunakea AK · Nutrients · 2024-05-07

Preclinical / mechanistic

74. Sex-specific effects of ketogenic diet on anxiety-like behavior and neuroimmune response in C57Bl/6J mice.

Kumar M, Bhatt B, Gusain C, Mahajan N, Bishnoi M · The Journal of nutritional biochemistry · 2024-02-02

Other

75. Immune-Modulating Effects of Low-Carbohydrate Ketogenic Foods in Healthy Canines.

Tavener SK, Jackson MI, Panickar KS · Current developments in nutrition · 2024-02-28

Other

76. Ketone bodies as chemical signals for the immune system.

Gonzatti MB, Goldberg EL · American journal of physiology. Cell physiology · 2024-01-08

Randomized clinical trial

77. The Effect of a Ketogenic Diet versus Mediterranean Diet on Clinical and Biochemical Markers of Inflammation in Patients with Obesity and Psoriatic Arthritis: A Randomized Crossover Trial.

Lambadiari V, Katsimbri P, Kountouri A, Korakas E, Papathanasi A, Maratou E, Pavlidis G, Pliouta L, Ikonomidis I, Malisova S, Vlachos D, Papadavid E · International journal of molecular sciences · 2024-02-20

Clinical trial / intervention

78. Differential peripheral immune signatures elicited by vegan versus ketogenic diets in humans.

Link VM, Subramanian P, Cheung F, Han KL, Stacy A, Chi L, Sellers BA, Koroleva G, Courville AB, Mistry S, Burns A, Apps R, Hall KD, Belkaid Y · Nature medicine · 2024-01-30

Preclinical / mechanistic

79. A High MCT-Based Ketogenic Diet Suppresses Th1 and Th17 Responses to Ameliorate Experimental Autoimmune Encephalomyelitis in Mice by Inhibiting GSDMD and JAK2-STAT3/4 Pathways.

Zhang Q, Sun W, Wang Q, Zheng X, Zhang R, Zhang N · Molecular nutrition & food research · 2023-12-06

Clinical trial / intervention

80. Impact of fasting & ketogenic interventions on the NLRP3 inflammasome: A narrative review.

Neudorf H, Little JP · Biomedical journal · 2023-11-07

Preclinical / mechanistic

81. Ketogenic Diet Reduces Age-Induced Chronic Neuroinflammation in Mice.

Nomura M, Murad NF, Madhavan SS, Mu WC, Eap B, Garcia TY, Aguirre CG, Verdin E, Ellerby L, Furman D, Newman JC · Aging biology · 2024-12-16

Preclinical / mechanistic

82. Ketogenic Diet Alleviates Mechanical Allodynia in the Models of Inflammatory and Neuropathic Pain in Male Mice.

Eto K, Ogata M, Toyooka Y, Hayashi T, Ishibashi H · Biological & pharmaceutical bulletin · 2024-03-19

Review

83. Is ketogenic diet a 'precision medicine'? Recent developments and future challenges.

Falsaperla R, Sortino V, Striano P, Kluger G, Ramantani G, Ruggieri M, Network for Therapy in Rare Epilepsies (NETRE) · European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society · 2023-11-15

Review

84. The effect of the ketogenic diet on Acne: Could it be a therapeutic tool?

Barrea L, Cacciapuoti S, Megna M, Verde L, Marasca C, Vono R, Camajani E, Colao A, Savastano S, Fabbrocini G, Muscogiuri G · Critical reviews in food science and nutrition · 2023-02-13

Preclinical / mechanistic

85. A ketogenic diet reduces age-induced chronic neuroinflammation in mice Running title: ketogenic diet and brain inflammaging.

Nomura M, Murad NF, Madhavan SS, Eap B, Garcia TY, Aguirre CG, Verdin E, Ellerby L, Furman D, Newman JC · bioRxiv : the preprint server for biology · 2023-12-04

Clinical trial / intervention

86. Ketogenic diet alleviates cognitive dysfunction and neuroinflammation in APP/PS1 mice via the Nrf2/HO-1 and NF-κB signaling pathways.

Jiang J, Pan H, Shen F, Tan Y, Chen S · Neural regeneration research · 2023-07-14

Clinical trial / intervention

87. Low-carbohydrate and ketogenic diets: a scoping review of neurological and inflammatory outcomes in human studies and their relevance to chronic pain.

Field R, Field T, Pourkazemi F, Rooney K · Nutrition research reviews · 2022-04-19

Preclinical / mechanistic

88. A ketogenic diet can mitigate SARS-CoV-2 induced systemic reprogramming and inflammation.

Palermo A, Li S, Ten Hoeve J, Chellappa A, Morris A, Dillon B, Ma F, Wang Y, Cao E, Shabane B, Acín-Perez R, Petcherski A, Lusis AJ, Hazen S, Shirihai OS, Pellegrini M, Arumugaswami V, Graeber TG, Deb A · Communications biology · 2023-11-03

Preclinical / mechanistic

89. Ketogenic diet changes microglial morphology and the hippocampal lipidomic profile differently in stress susceptible versus resistant male mice upon repeated social defeat.

González Ibáñez F, Halvorson T, Sharma K, McKee CG, Carrier M, Picard K, Vernoux N, Bisht K, Deslauriers J, Lalowski M, Tremblay MÈ · Brain, behavior, and immunity · 2023-09-07

Other

90. Ketogenic Diets in Children With Intractable Epilepsy and its Effects on Gastrointestinal Function, Gut Microbiome, Inflammation, and Quality of Life.

Menzies J, Sundararaj A, Cardamone M, McHarg A, Leach S, Krishnan U · Journal of pediatric gastroenterology and nutrition · 2023-09-08

Other

91. Changes in lipids and inflammation in adults with super-refractory status epilepticus on a ketogenic diet.

Dickens AM, Johnson TP, Lamichhane S, Kumar A, Pardo CA, Gutierrez EG, Haughey N, Cervenka MC · Frontiers in molecular biosciences · 2023-10-23

Clinical trial / intervention

92. Ketogenic Diet as a Possible Non-pharmacological Therapy in Main Endocrine Diseases of the Female Reproductive System: A Practical Guide for Nutritionists.

Camajani E, Feraco A, Verde L, Moriconi E, Marchetti M, Colao A, Caprio M, Muscogiuri G, Barrea L · Current obesity reports · 2023-07-05

Preclinical / mechanistic

93. Overcome Prostate Cancer Resistance to Immune Checkpoint Therapy with Ketogenic Diet-Induced Epigenetic Reprogramming.

Murphy S, Rahmy S, Gan D, Zhu Y, Manyak M, Li J, Lu X, Lu X · bioRxiv : the preprint server for biology · 2023-08-08

Preclinical / mechanistic

94. Ketogenic diet ameliorates autism spectrum disorders-like behaviors via reduced inflammatory factors and microbiota remodeling in BTBR T+ Itpr3tf/J mice.

Olivito I, Avolio E, Minervini D, Soda T, Rocca C, Angelone T, Iaquinta FS, Bellizzi D, De Rango F, Bruno R, De Bartolo L, Alò R, Canonaco M, Facciolo RM · Experimental neurology · 2023-05-05

Preclinical / mechanistic

95. Ketogenic diet attenuates neuroinflammation and induces conversion of M1 microglia to M2 in an EAE model of multiple sclerosis by regulating the NF-κB/NLRP3 pathway and inhibiting HDAC3 and P2X7R activation.

Sun W, Wang Q, Zhang R, Zhang N · Food & function · 2023-07-31

Clinical trial / intervention

96. A ketogenic diet substantially reshapes the human metabolome.

Effinger D, Hirschberger S, Yoncheva P, Schmid A, Heine T, Newels P, Schütz B, Meng C, Gigl M, Kleigrewe K, Holdt LM, Teupser D, Kreth S · Clinical nutrition (Edinburgh, Scotland) · 2023-05-04

Preclinical / mechanistic

97. Ketogenic Diet Alleviates Hypoglycemia-Induced Neuroinflammation via Modulation the Gut Microbiota in Mice.

Li C, Pan J, Sun P, Wang S, Wang S, Feng W, Chen S, Chai X, Zhao S, Zhu X · Molecular nutrition & food research · 2023-04-25

Clinical trial / intervention

98. The effect of isocaloric, energy-restrictive, KETOgenic diet on metabolism, inflammation, nutrition deficiencies and oxidative stress in women with overweight and obesity (KETO-MINOX): Study protocol.

Drabińska N, Romaszko J, White P · PloS one · 2023-05-08

Preclinical / mechanistic

99. Donkey Oil-Based Ketogenic Diet Prevents Tumor Progression by Regulating Intratumor Inflammation, Metastasis and Angiogenesis in CT26 Tumor-Bearing Mice.

Zhang H, Xie L, Zhang N, Qi X, Lu T, Xing J, Akhtar MF, Li L, Liu G · Genes · 2023-04-30

Preclinical / mechanistic

100. Impact of Maternal Ketogenic Diet on NLRP3 Inflammasome Response in the Offspring Brain.

Altınöz S, Micili SC, Soy S, Engür D, Baysal B, Kumral A · Nutrients · 2023-04-21

Preclinical / mechanistic

101. Ketogenic diet restrains herpes simplex encephalitis via gut microbes.

Shan T, Huang Y, Zhao Z, Li F, Wang Y, Ye C, Zheng K, Ren Z · Microbes and infection · 2022-10-18

Clinical trial / intervention

102. Effect of Low-Carbohydrate Diet on Beta-Hydroxybutyrate Ketogenesis Metabolic Stimulation and Regulation of NLRP3 Ubiquitination in Obese Saudi Women.

Binobead MA, Aldakhilallah AH, Alsedairy SA, Al-Harbi LN, Al-Qahtani WH, Alshammari GM · Nutrients · 2023-02-05

Clinical trial / intervention

103. Ketogenic Diet as a Promising Non-Drug Intervention for Alzheimer's Disease: Mechanisms and Clinical Implications.

Xu Y, Zheng F, Zhong Q, Zhu Y · Journal of Alzheimer's disease : JAD · 2023-04-25

Review

104. Ketogenic Diet and Inflammation: Implications for Mood and Anxiety Disorders.

El Karkafi R, Gebara T, Salem M, Kamel J, El Khoury G, Zalal M, Fakhoury M · Advances in experimental medicine and biology · 2023-03-23

Other

105. Phase angle as biomarker of inflammatory changes during very low-calorie ketogenic diet.

Barrea L, Muscogiuri G, Savastano S · International journal of obesity (2005) · 2022-08-24

Clinical trial / intervention

106. Could very low-calorie ketogenic diets turn off low grade inflammation in obesity? Emerging evidence.

Barrea L, Caprio M, Watanabe M, Cammarata G, Feraco A, Muscogiuri G, Verde L, Colao A, Savastano S · Critical reviews in food science and nutrition · 2022-04-04

Preclinical / mechanistic

107. Exogenous ketone ester administration attenuates systemic inflammation and reduces organ damage in a lipopolysaccharide model of sepsis.

Soni S, Martens MD, Takahara S, Silver HL, Maayah ZH, Ussher JR, Ferdaoussi M, Dyck JRB · Biochimica et biophysica acta. Molecular basis of disease · 2022-07-25

Clinical trial / intervention

108. Activation of G protein-coupled receptors by ketone bodies: Clinical implication of the ketogenic diet in metabolic disorders.

Spigoni V, Cinquegrani G, Iannozzi NT, Frigeri G, Maggiolo G, Maggi M, Parello V, Dei Cas A · Frontiers in endocrinology · 2022-10-20

Review

109. The Therapeutic Role of Short-Chain Fatty Acids Mediated Very Low-Calorie Ketogenic Diet-Gut Microbiota Relationships in Paediatric Inflammatory Bowel Diseases.

Alsharairi NA · Nutrients · 2022-10-03

Clinical trial / intervention

110. The Anti-Inflammatory Effect of Preventive Intervention with Ketogenic Diet Mediated by the Histone Acetylation of mGluR5 Promotor Region in Rat Parkinson's Disease Model: A Dual-Tracer PET Study.

Zhu Y, Tang X, Cheng Z, Dong Q, Ruan G · Parkinson's disease · 2022-09-05

Clinical trial / intervention

111. The ketogenic diet prevents steatosis and insulin resistance by reducing lipogenesis, diacylglycerol accumulation and protein kinase C activity in male rat liver.

Jani S, Da Eira D, Stefanovic M, Ceddia RB · The Journal of physiology · 2022-09-04

Clinical trial / intervention

112. Phase angle as an easy diagnostic tool for the nutritionist in the evaluation of inflammatory changes during the active stage of a very low-calorie ketogenic diet.

Barrea L, Muscogiuri G, Aprano S, Vetrani C, de Alteriis G, Varcamonti L, Verde L, Colao A, Savastano S · International journal of obesity (2005) · 2022-05-25

Review

113. Beta-Hydroxybutyrate: A Dual Function Molecular and Immunological Barrier Function Regulator.

Qi J, Gan L, Fang J, Zhang J, Yu X, Guo H, Cai D, Cui H, Gou L, Deng J, Wang Z, Zuo Z · Frontiers in immunology · 2022-06-16

Other

114. Ketone Bodies Improve Human CD8+ Cytotoxic T-Cell Immune Response During COVID-19 Infection.

Hirschberger S, Gellert L, Effinger D, Muenchhoff M, Herrmann M, Briegel JM, Zwißler B, Kreth S · Frontiers in medicine · 2022-06-16

Review

115. Ketogenic and Modified Mediterranean Diet as a Tool to Counteract Neuroinflammation in Multiple Sclerosis: Nutritional Suggestions.

Di Majo D, Cacciabaudo F, Accardi G, Gambino G, Giglia G, Ferraro G, Candore G, Sardo P · Nutrients · 2022-06-08

Preclinical / mechanistic

116. Ketogenic diet ameliorates inflammation by inhibiting the NLRP3 inflammasome in osteoarthritis.

Kong G, Wang J, Li R, Huang Z, Wang L · Arthritis research & therapy · 2022-05-18

Randomized clinical trial

117. Short Term Isocaloric Ketogenic Diet Modulates NLRP3 Inflammasome Via B-hydroxybutyrate and Fibroblast Growth Factor 21.

Kim ER, Kim SR, Cho W, Lee SG, Kim SH, Kim JH, Choi E, Kim JH, Yu JW, Lee BW, Kang ES, Cha BS, Lee MS, Cho JW, Jeon JY, Lee YH · Frontiers in immunology · 2022-04-28

Clinical trial / intervention

118. Ketogenic diet ameliorates cognitive impairment and neuroinflammation in a mouse model of Alzheimer's disease.

Xu Y, Jiang C, Wu J, Liu P, Deng X, Zhang Y, Peng B, Zhu Y · CNS neuroscience & therapeutics · 2021-12-10

Other

119. Beneficial Effects of the Very-Low-Calorie Ketogenic Diet on the Symptoms of Male Accessory Gland Inflammation.

Condorelli RA, Aversa A, Basile L, Cannarella R, Mongioì LM, Cimino L, Perelli S, Caprio M, Cimino S, Calogero AE, La Vignera S · Nutrients · 2022-03-04

Preclinical / mechanistic

120. A ketogenic diet attenuates acute and chronic ischemic kidney injury and reduces markers of oxidative stress and inflammation.

Rojas-Morales P, León-Contreras JC, Sánchez-Tapia M, Silva-Palacios A, Cano-Martínez A, González-Reyes S, Jiménez-Osorio AS, Hernández-Pando R, Osorio-Alonso H, Sánchez-Lozada LG, Tovar AR, Pedraza-Chaverri J, Tapia E · Life sciences · 2021-12-16

Other

121. Effect of very low-calorie ketogenic diet in combination with omega-3 on inflammation, satiety hormones, body composition, and metabolic markers. A pilot study in class I obese subjects.

Rondanelli M, Perna S, Ilyas Z, Peroni G, Bazire P, Sajuox I, Maugeri R, Nichetti M, Gasparri C · Endocrine · 2021-09-16

Preclinical / mechanistic

122. Ketogenic diet aggravates colitis, impairs intestinal barrier and alters gut microbiota and metabolism in DSS-induced mice.

Li S, Zhuge A, Wang K, Lv L, Bian X, Yang L, Xia J, Jiang X, Wu W, Wang S, Wang Q, Li L · Food & function · 2021-10-19

Clinical trial / intervention

123. Ketogenic diet prevents paclitaxel-induced neuropathic nociception through activation of PPARγ signalling pathway and inhibition of neuroinflammation in rat dorsal root ganglion.

Zhong S, Zhou Z, Lin X, Liu F, Liu C, Liu Z, Deng W, Zhang X, Chang H, Zhao C · The European journal of neuroscience · 2021-08-02

Preclinical / mechanistic

124. Ketogenic diet restrains aging-induced exacerbation of coronavirus infection in mice.

Ryu S, Shchukina I, Youm YH, Qing H, Hilliard B, Dlugos T, Zhang X, Yasumoto Y, Booth CJ, Fernández-Hernando C, Suárez Y, Khanna K, Horvath TL, Dietrich MO, Artyomov M, Wang A, Dixit VD · eLife · 2021-06-21

Observational human study

125. Ketogenic Diet Therapy for the Treatment of Post-encephalitic and Autoimmune-Associated Epilepsies.

Husari KS, Cervenka MC · Frontiers in neurology · 2021-06-16

Preclinical / mechanistic

126. Ketogenic diet-mediated steroid metabolism reprogramming improves the immune microenvironment and myelin growth in spinal cord injury rats according to gene and co-expression network analyses.

Zeng H, Lu Y, Huang MJ, Yang YY, Xing HY, Liu XX, Zhou MW · Aging · 2021-05-06

Case report / case series

127. Ketogenic Diet Therapy for Intractable Epilepsy in Infantile Alexander Disease: A Small Case Series and Analyses of Astroglial Chemokines and Proinflammatory Cytokines.

Hamada S, Kato T, Kora K, Kawaguchi T, Okubo T, Ide M, Tanaka T, Yoshida T, Sakakibara T · Epilepsy research · 2020-12-03

Preclinical / mechanistic

128. Ketogenic diet effects on inflammatory allodynia and ongoing pain in rodents.

Ruskin DN, Sturdevant IC, Wyss LS, Masino SA · Scientific reports · 2021-01-12

Other

129. [Obesity, inflammation and COVID-19: preventive interest of ketogenic diet?].

Charlot A, Boumiza R, Roux M, Zoll J · Biologie aujourd'hui · 2021-08-16

Review

130. Ketogenic diet and Neuroinflammation.

Koh S, Dupuis N, Auvin S · Epilepsy research · 2020-09-06

Clinical trial / intervention

131. Short-Term Physiological Effects of a Very Low-Calorie Ketogenic Diet: Effects on Adiponectin Levels and Inflammatory States.

Monda V, Polito R, Lovino A, Finaldi A, Valenzano A, Nigro E, Corso G, Sessa F, Asmundo A, Nunno ND, Cibelli G, Messina G · International journal of molecular sciences · 2020-05-02

Preclinical / mechanistic

132. Ketogenic diet affects immune cells in mice.

Greenhill C · Nature reviews. Endocrinology · 2020-02-01

Randomized clinical trial

133. Ketogenic diet and fasting diet as Nutritional Approaches in Multiple Sclerosis (NAMS): protocol of a randomized controlled study.

Bahr LS, Bock M, Liebscher D, Bellmann-Strobl J, Franz L, Prüß A, Schumann D, Piper SK, Kessler CS, Steckhan N, Michalsen A, Paul F, Mähler A · Trials · 2020-01-02

Other

134. Ketogenic diet and adipose tissue inflammation-a simple story? Fat chance!

Stubbs BJ, Newman JC · Nature metabolism · 2020-07-23

Preclinical / mechanistic

135. Metabolic and Inflammatory Effects of an ω-3 Fatty Acid-Based Eucaloric Ketogenic Diet in Mice With Endotoxemia.

Anez-Bustillos L, Dao DT, Finkelstein A, Pan A, Cho BS, Mitchell PD, Gura KM, Bistrian BR, Puder M · JPEN. Journal of parenteral and enteral nutrition · 2019-08-21

Other

136. Pilot study of a ketogenic diet in relapsing-remitting MS.

Brenton JN, Banwell B, Bergqvist AGC, Lehner-Gulotta D, Gampper L, Leytham E, Coleman R, Goldman MD · Neurology(R) neuroimmunology & neuroinflammation · 2019-04-12

Other

137. Glucose and Lipid Homeostasis and Inflammation in Humans Following an Isocaloric Ketogenic Diet.

Rosenbaum M, Hall KD, Guo J, Ravussin E, Mayer LS, Reitman ML, Smith SR, Walsh BT, Leibel RL · Obesity (Silver Spring, Md.) · 2019-05-08

Review

138. Anticatabolic Effects of Ketone Bodies in Skeletal Muscle.

Koutnik AP, D'Agostino DP, Egan B · Trends in endocrinology and metabolism: TEM · 2019-01-31

Randomized clinical trial

139. Ketogenic diets attenuate cyclooxygenase and lipoxygenase gene expression in multiple sclerosis.

Bock M, Karber M, Kuhn H · EBioMedicine · 2018-10-03

Preclinical / mechanistic

140. Ketogenic diet attenuates oxidative stress and inflammation after spinal cord injury by activating Nrf2 and suppressing the NF-κB signaling pathways.

Lu Y, Yang YY, Zhou MW, Liu N, Xing HY, Liu XX, Li F · Neuroscience letters · 2018-06-09

Review

141. Do ketone bodies mediate the anti-seizure effects of the ketogenic diet?

Simeone TA, Simeone KA, Stafstrom CE, Rho JM · Neuropharmacology · 2018-01-08

Review

142. Anti-Oxidant and Anti-Inflammatory Activity of Ketogenic Diet: New Perspectives for Neuroprotection in Alzheimer's Disease.

Pinto A, Bonucci A, Maggi E, Corsi M, Businaro R · Antioxidants (Basel, Switzerland) · 2018-04-28

Preclinical / mechanistic

143. Ketogenic Diet Improves Brain Ischemic Tolerance and Inhibits NLRP3 Inflammasome Activation by Preventing Drp1-Mediated Mitochondrial Fission and Endoplasmic Reticulum Stress.

Guo M, Wang X, Zhao Y, Yang Q, Ding H, Dong Q, Chen X, Cui M · Frontiers in molecular neuroscience · 2018-03-20

Preclinical / mechanistic

144. Ketogenic diet improves behaviors in a maternal immune activation model of autism spectrum disorder.

Ruskin DN, Murphy MI, Slade SL, Masino SA · PloS one · 2017-02-06

Clinical trial / intervention

145. Obesity and tumor growth: inflammation, immunity, and the role of a ketogenic diet.

Wright C, Simone NL · Current opinion in clinical nutrition and metabolic care · 2016-05-12

Randomized clinical trial

146. Eucaloric Ketogenic Diet Reduces Hypoglycemia and Inflammation in Mice with Endotoxemia.

Nandivada P, Fell GL, Pan AH, Nose V, Ling PR, Bistrian BR, Puder M · Lipids · 2016-04-27

Other

147. Short-term effects of ketogenic diet on anthropometric parameters, body fat distribution, and inflammatory cytokine production in GLUT1 deficiency syndrome.

Bertoli S, Neri IG, Trentani C, Ferraris C, De Amicis R, Battezzati A, Veggiotti P, De Giorgis V, Tagliabue A · Nutrition (Burbank, Los Angeles County, Calif.) · 2015-03-31

Preclinical / mechanistic

148. Ketogenic diet exhibits anti-inflammatory properties.

Dupuis N, Curatolo N, Benoist JF, Auvin S · Epilepsia · 2015-05-23

Preclinical / mechanistic

149. Ketogenic Diet Impairs FGF21 Signaling and Promotes Differential Inflammatory Responses in the Liver and White Adipose Tissue.

Asrih M, Altirriba J, Rohner-Jeanrenaud F, Jornayvaz FR · PloS one · 2015-05-14

Preclinical / mechanistic

150. Inflammation-mediated memory dysfunction and effects of a ketogenic diet in a murine model of multiple sclerosis.

Kim DY, Hao J, Liu R, Turner G, Shi FD, Rho JM · PloS one · 2012-05-02

Preclinical / mechanistic

151. Ketogenic diet-induced peroxisome proliferator-activated receptor-γ activation decreases neuroinflammation in the mouse hippocampus after kainic acid-induced seizures.

Jeong EA, Jeon BT, Shin HJ, Kim N, Lee DH, Kim HJ, Kang SS, Cho GJ, Choi WS, Roh GS · Experimental neurology · 2011-09-14

Preclinical / mechanistic

152. Hepatic steatosis, inflammation, and ER stress in mice maintained long term on a very low-carbohydrate ketogenic diet.

Garbow JR, Doherty JM, Schugar RC, Travers S, Weber ML, Wentz AE, Ezenwajiaku N, Cotter DG, Brunt EM, Crawford PA · American journal of physiology. Gastrointestinal and liver physiology · 2011-03-31

Preclinical / mechanistic

153. Neuroprotective and anti-inflammatory activities of ketogenic diet on MPTP-induced neurotoxicity.

Yang X, Cheng B · Journal of molecular neuroscience : MN · 2010-03-24

Preclinical / mechanistic

154. Reduced pain and inflammation in juvenile and adult rats fed a ketogenic diet.

Ruskin DN, Kawamura M, Masino SA · PloS one · 2009-12-23

Preclinical / mechanistic

155. Ketogenic diet attenuates Müller cell activation and retinal neuroinflammation in autoimmune glaucoma through acetylation‑mediated FOXO signalling.

Tan S, Wang X, Zheng Y, Mou Z, Zeng L, Yuan J, Fan X, Wei M, Huo Y, Ouyang R, Pu Y, Lei J, Gao X, Wang D, Peng Y, Li H · International journal of molecular medicine · 2026-09-18

Review

156. Exploring the Ketogenic Diet as Adjunctive Therapy in Multiple Sclerosis: A Review.

Rasheed S, Uzair M, Anas M, Batool Naqvi SS, Aijaz U, Raza AA, Samadi A · Restorative neurology and neuroscience · 2025-12-10

Observational human study

157. Very low energy ketogenic therapy: an anti-inflammatory medical nutritional approach for MASLD in obesity.

Barrea L, Verde L, Galasso M, Savastano S, Colao A, Muscogiuri G · Journal of translational medicine · 2025-12-17

Clinical trial / intervention

158. Changing chronomics of clock, immune and Parkinson's disease-associated genes in SCN and SN with aging in male Wistar rats: ketogenic diet intervention.

Sharma SA, Jagota A · Biogerontology · 2025-12-08

Clinical trial / intervention

159. The ketogenic diet in Parkinson's disease: a potential therapeutic strategy.

Pokora B, Pokora K, Binienda A, Fichna J · Pharmacological reports : PR · 2025-11-07

Systematic review / meta-analysis

160. The role and benefits of ketogenic diet in modulating inflammation in multiple sclerosis: A systematic review and meta-analysis.

Reddy NJ, Benjamin NZY, Reddy PH, Thai A, Rawashdeh HMA, Saravanan C, Prajjwal P, Tekuru Y, Inban P, John J · Disease-a-month : DM · 2025-10-09

Other

161. Foreword: Role of Bruton tyrosine kinase inhibitors and ketogenic diet for inflammatory modulation in multiple sclerosis.

Disease-a-month : DM · 2025-09-09

Clinical trial / intervention

162. Breaking the metabolic-inflammatory vicious cycle in polycystic ovary syndrome: a comparative review of ketogenic and high-fat diets.

Yang W, Pang N, He X · Lipids in health and disease · 2025-10-06

Preclinical / mechanistic

163. Ketogenic Diet Mitigates Age-Related Cognitive Decline and Neuroinflammation in Rats, While Antibiotics Exacerbate Brain Health Risks.

Sayin O, Ilgin R, Akkaya EC, Ates M, Hosgorler F · Journal of molecular neuroscience : MN · 2025-09-10

Clinical trial / intervention

164. Beyond energy metabolism: ketogenic diet and β-hydroxybutyrate protect against intestinal ischemia-reperfusion injury through anti-inflammatory and barrier-preserving effects.

Wang FX, Wei N, Dai SY, Zhong X, Mu G, Fan X, Chen SR, Chen Y, Zhou J · Biochemical and biophysical research communications · 2025-06-18

Randomized clinical trial

165. Fasting, ketogenic, and anti-inflammatory diets in multiple sclerosis: a randomized controlled trial with 18-month follow-up.

Bahr LS, Bellmann-Strobl J, Koppold DA, Rust R, Schmitz-Hübsch T, Olszewska M, Stadlbauer J, Bock M, Scheel M, Chien C, Multmeier J, Krannich A, Michalsen A, Paul F, Mähler A · BMC nutrition · 2025-08-20

Preclinical / mechanistic

166. Protective Effects of the Ketogenic Diet on Cognitive Impairment Induced by Status Epilepticus in Rats: Modulation of Neuroinflammation Through the NF-κB Signaling Pathway.

Wang W, Wang L, Jiang C, Zhang S, Tan C, Peng L, Ding R, Tian B, Song X, Jiang L · Pediatric discovery · 2025-06-23

Preclinical / mechanistic

167. Ketogenic diet attenuates microglia-mediated neuroinflammation by inhibiting NLRP3 inflammasome activation via HDAC3 inhibition to activate mitophagy in experimental autoimmune encephalomyelitis.

Zhang Q, Zheng M, Sun W, Loers G, Wen M, Wang Q, Zheng X, Siebert HC, Zhang R, Zhang N · Food & function · 2025-06-16

Randomized clinical trial

168. Effects of a continuous remote care intervention including nutritional ketosis on kidney function and inflammation in adults with type 2 diabetes: a post-hoc latent class trajectory analysis.

Athinarayanan SJ, Roberts CGP, Phinney SD, Weimbs T, Friedman AN, Volek JS · Frontiers in nutrition · 2025-06-06

Preclinical / mechanistic

169. A high-saturated, long-chain fatty acid ketogenic diet negatively impacts visual and motor-sensory function in a pre-clinical model of multiple sclerosis.

Capper EN, Anders JJ, Elwood BW, Kardon RH, Gramlich OW · Frontiers in immunology · 2025-05-22

Clinical trial / intervention

170. Ketogenic diet attenuates neuroinflammation and restores hippocampal neurogenesis to improve CUMS induced depression-like behavior in mice.

Liang J, Zhang J, Sun J, Liang Q, Zhan Y, Yang Z, Zhang Y, Jin L, Hu C, Zhao YT · Food & function · 2025-05-06

Preclinical / mechanistic

171. Hepatic toll of keto: unveiling the inflammatory and structural consequences of ketogenic diet in rats.

Rezazadeh K, Barzegar M, Nezamdoost E, Shoaran M, Abbasi MM, Ghasemi B, Madadi S, Raeisi S · BMC nutrition · 2025-04-09

Randomized clinical trial

172. Effect of the modified Atkins diet on NLRP3, caspase-1, IL-ιβ, and IL-10 in patients with tetralogy of Fallot undergoing open-heart surgery: A randomized controlled trial.

Yanuarso PB, Djer MM, Hendarto A, Pudjiadi AH, Rachmadi L, Wibowo H, Advani N, Murni IK, Kekalih A, Sukardi R, Dilawar I, Susanti DS, Supriatna N · Narra J · 2025-03-24

Preclinical / mechanistic

173. Vegetal oil-based ketogenic diet improves inflammation and fibrosis in experimental metabolic dysfunction-associated steatohepatitis.

Provera A, Ramavath NN, Gadipudi LL, Vecchio C, Caputo M, Antonioli A, Tini S, Sheferaw AN, Reano S, Filigheddu N, Manfredi M, Barberis E, Cocolin L, Ferrocino I, Locatelli M, Caprio M, Tacke F, Albano E, Prodam F, Sutti S · Frontiers in immunology · 2025-04-01

Preclinical / mechanistic

174. Sex-Specific Anti-Inflammatory Effects of a Ketogenic Diet in a Mouse Model of Allergic Airway Inflammation.

Ekpruke CD, Borges-Sosa O, Hassel CA, Rousselle D, Dinwiddie L, Babayev M, Bakare A, Silveyra P · International journal of molecular sciences · 2025-03-26

Preclinical / mechanistic

175. Combined treatment of Ketogenic diet and propagermanium reduces neuroinflammation in Tay-Sachs disease mouse model.

Inci OK, Seyrantepe V · Metabolic brain disease · 2025-02-28

Preclinical / mechanistic

176. Ketogenic diet induces an inflammatory reactive astrocytes phenotype reducing glioma growth.

Rosito M, Maqbool J, Reccagni A, Mangano M, D'Andrea T, Rinaldi A, Peruzzi G, Silvestri B, Rosa A, Trettel F, D'Alessandro G, Catalano M, Fucile S, Limatola C · Cellular and molecular life sciences : CMLS · 2025-02-08

Review

177. A ketogenic diet regulates microglial activation to treat drug addiction.

Ji J, Tang Y · Frontiers in pharmacology · 2025-01-23

Review

178. Potential inflammatory mechanisms of the ketogenic diet against febrile infection-related epilepsy syndrome.

Wang J, Xie L, Jiang L · Acta epileptologica · 2025-01-10

Women’s Health

Endometriosis Recent peer-reviewed literature

Source-audited selection from the connected PDF archive. Systematic reviews/meta-analyses and recent human evidence are prioritized when available; sparse areas are explicitly kept sparse.

Randomized controlled clinical trial · 2025

1. MCT-Modified Ketogenic Diet as an Adjunct to Standard Treatment Regimen Could Alleviate Clinical Symptoms in Women with Endometriosis

Original publication title: MCT-Modified Ketogenic Diet as an Adjunct to Standard Treatment Regimen Could Alleviate Clinical Symptoms in Women with Endometriosis

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Clinical trial / intervention

2. Effectiveness of Medical Nutrition Therapy in the Management of Patients with Obesity and Endometriosis: from the Mediterranean Diet To the Ketogenic Diet, Through Supplementation. The Role of the Nutritionist in Clinical Management.

Barrea L, Verde L, Annunziata G, Chedraui P, Petraglia F, Cucalón G, Camajani E, Caprio M, Gorini S, Iorio GG, Di Girolamo R, Carbone L, Chapela S, Frias-Toral E, Muscogiuri G · Current obesity reports · 2025-09-08

Reproduction & Fertility Recent peer-reviewed literature

Source-audited selection from the connected PDF archive. Systematic reviews/meta-analyses and recent human evidence are prioritized when available; sparse areas are explicitly kept sparse.

Human prospective case series

1. Prospective Observational Case Series in Infertile Women with Overweight or Obesity Treated with a Very-Low-Calorie Ketogenic Diet Prior to In Vitro Fertilization

Original publication title: Prospective Observational Case Series in Infertile Women with Overweight or Obesity Treated with a Very-Low-Calorie Ketogenic Diet Prior to In Vitro Fertilization

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Review

2. Ketogenic Diet as a Possible Non-Pharmacological Therapy in Endocrine Diseases of the Female Reproductive System

Original publication title: Ketogenic Diet as a Possible Non-Pharmacological Therapy in Endocrine Diseases of the Female Reproductive System

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Human clinical evidence

3. Beneficial Effects of the Very-Low-Calorie Ketogenic Diet on Reproductive and Metabolic Parameters

Original publication title: Beneficial Effects of the Very-Low-Calorie Ketogenic Diet on Reproductive and Metabolic Parameters

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Systematic / endocrine evidence

4. Low-Carbohydrate Diets and Men’s Cortisol and Testosterone

Original publication title: Low-Carbohydrate Diets and Men’s Cortisol and Testosterone

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Review

5. The Effect of Low Carbohydrate Diets on Fertility

Original publication title: The Effect of Low Carbohydrate Diets on Fertility

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Review

6. [Research progress on the role and mechanism of ketogenic diet in regulating gametogenesis].

Zhang T, Cao C, Pang W · Sheng wu gong cheng xue bao = Chinese journal of biotechnology · 2026-08-25

Clinical trial / intervention

7. Effect of Ketogenic Diet Versus Vegan Diet on Obesity-Induced Testicular Dysfunction and Mediating Role of Gut Microbiota.

Salama SA, Hassan NH, Abdelhadi AA, Soliman EK, Soliman AHM, Malek MM, Atia RRA, Mohamed SRA, Wahid IM, Salem IM, Aldisi D, Abulmeaty MMA, Abdal-Hay A, Wahid RM · International journal of molecular sciences · 2026-07-27

Systematic review / meta-analysis

8. Dietary Interventions and Testosterone Levels in Obese Men: A Systematic Review Comparing the Mediterranean Diet, Ketogenic Diet, and Intermittent Fasting.

La Vignera S, Condorelli RA · Nutrients · 2026-07-24

Systematic review / meta-analysis

9. Ketogenic diet as a therapeutic intervention for biochemical hyperandrogenism in PCOS women with obesity or overweight: a meta-analytic study.

Maseroli E, Alfaroli C, Cirillo M, Ravelli SA, Lambrinoudaki I, Focardi M, Virgili G, Vignozzi L · Journal of endocrinological investigation · 2026-06-13

Preclinical / mechanistic

10. A ketogenic diet alleviates the apoptosis of granulosa cells by inhibiting the activation of cGAS-STING signaling pathway in PCOS mice.

Zhao B, Wu H, Yao Q, Bai W, Kang J · Cell communication and signaling : CCS · 2024-11-27

Observational human study

11. Ketogenic diet improves fertility in patients with polycystic ovary syndrome: a brief report.

Tsushima Y, Nachawi N, Pantalone KM, Griebeler ML, Alwahab UA · Frontiers in nutrition · 2024-09-12

Randomized clinical trial

12. Self-reported menses physiology is positively modulated by a well-formulated, energy-controlled ketogenic diet vs. low fat diet in women of reproductive age with overweight/obesity.

Kackley ML, Buga A, Brownlow ML, O'Connor A, Sapper TN, Crabtree CD, Robinson BT, Stoner JT, Decker DD, Soma L, Volek JS · PloS one · 2024-08-16

Randomized clinical trial

13. Three Weeks on a Ketogenic Diet Reduces Free Testosterone and Free Estradiol in Middle-Aged Obese Men and Women.

Svart M, Rittig N, Luong TV, Gopalasingam N, Vestergaard ET, Gormsen L, Søndergaard E, Thomsen HH, Gravholt CH · Journal of nutrition and metabolism · 2024-08-06

Systematic review / meta-analysis

14. Ketogenic Diet and Multiple Health Outcomes: An Umbrella Review of Meta-Analysis.

Chen S, Su X, Feng Y, Li R, Liao M, Fan L, Liu J, Chen S, Zhang S, Cai J, Zhu S, Niu J, Ye Y, Lo K, Zeng F · Nutrients · 2023-09-27

Clinical trial / intervention

15. Effects of Ketogenic Diet on Reproductive Hormones in Women With Polycystic Ovary Syndrome.

Khalid K, Apparow S, Mushaddik IL, Anuar A, Rizvi SAA, Habib A · Journal of the Endocrine Society · 2023-09-07

Clinical trial / intervention

16. Ketogenic Diet as a Possible Non-pharmacological Therapy in Main Endocrine Diseases of the Female Reproductive System: A Practical Guide for Nutritionists.

Camajani E, Feraco A, Verde L, Moriconi E, Marchetti M, Colao A, Caprio M, Muscogiuri G, Barrea L · Current obesity reports · 2023-07-05

Clinical trial / intervention

17. Adding a ketogenic dietary intervention to IVF treatment in patients with polycystic ovary syndrome improves implantation and pregnancy.

Palafox-Gómez C, Ortiz G, Madrazo I, López-Bayghen E · Reproductive toxicology (Elmsford, N.Y.) · 2023-06-07

Clinical trial / intervention

18. Effects of a ketogenic diet on reproductive and metabolic phenotypes in mice with polycystic ovary syndrome†.

Liu S, Yao Q, Li X, Wu H, Sun C, Bai W, Kang J · Biology of reproduction · 2022-05-13

Systematic review / meta-analysis

19. Ketogenic state improves testosterone serum levels-results from a systematic review and meta-analysis.

Furini C, Spaggiari G, Simoni M, Greco C, Santi D · Endocrine · 2022-09-23

Preclinical / mechanistic

20. Ketogenic diet restores hormonal, apoptotic/proliferative balance and enhances the effect of metformin on a letrozole-induced polycystic ovary model in rats.

Ahmed AF, Sharkawi SS, AbdelHameed SS, Bayoumi AM, Moussa RS, Alhakamy NA, Al Sadoun H, Mansouri RA, El-Moselhy MA, El-Daly M, Anter AF · Life sciences · 2022-12-13

Other

21. Does the Ketogenic Diet Improve the Quality of Ovarian Function in Obese Women?

Magagnini MC, Condorelli RA, Cimino L, Cannarella R, Aversa A, Calogero AE, La Vignera S · Nutrients · 2022-10-06

Preclinical / mechanistic

22. Biochemical and histomorphological changes in testosterone propionate-induced benign prostatic hyperplasia in male Wistar rats treated with ketogenic diet.

Kayode OT, Owolabi AV, Kayode AAA · Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2020-10-28

Clinical trial / intervention

23. [The impact on metabolic and reproductive diseases of low-carbohydrate and ketogenic diets].

Moreno-Sepúlveda J, Capponi M · Revista medica de Chile · 2019-08-22

Clinical trial / intervention

24. Ketogenic Diet: an Endocrinologist Perspective.

Kuchkuntla AR, Shah M, Velapati S, Gershuni VM, Rajjo T, Nanda S, Hurt RT, Mundi MS · Current nutrition reports · 2019-11-11

Review

25. Ketogenic diet and testosterone increase: Is the increased cholesterol intake responsible? To what extent and under what circumstances can there be benefits?

Santos HO · Hormones (Athens, Greece) · 2017-09-30

Review

26. Should the ketogenic diet be considered for enhancing fertility?

Kulak D, Polotsky AJ · Maturitas · 2012-10-31

Other

27. The effects of a low-carbohydrate, ketogenic diet on the polycystic ovary syndrome: a pilot study.

Mavropoulos JC, Yancy WS, Hepburn J, Westman EC · Nutrition & metabolism · 2005-12-16

Preclinical / mechanistic

28. Prospective Observational Case Series in Infertile Women with Overweight or Obesity Treated with a Very-Low Calorie Ketogenic Diet (VLCKD) Prior to an In Vitro Fertilization (IVF) Treatment.

Casalechi M, Piontini A, Nicolosi A, Bergomas F, Napolitano F, Turolo S, Reschini M, Riccaboni A, Bellinghieri R, Somigliana E, Vigna L · Nutrients · 2025-09-11

Lipedema Recent peer-reviewed literature

Expanded source-audited selection. Systematic reviews/meta-analyses and recent human evidence are placed first; older clinical and mechanistic papers follow.

Recent clinical evidence · 2026

1. Management of lipedema with a biphasic ketogenic/low-carbohydrate diet

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Recent human study · 2025

2. Exploring the Anti-Inflammatory Potential of a Mediterranean-Style Ketogenic Diet in Women with Lipedema

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Recent review · 2025

3. Therapeutic Applications of Ketogenic Diets in Lipedema

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Review

4. The Efficacy of Ketogenic Diets as a Potential Nutritional Intervention for Lipedema

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Review

5. Ketogenic Diet: A Nutritional Therapeutic Tool for Lipedema

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Pilot clinical study

6. Modified Mediterranean-Ketogenic Diet and Carboxytherapy as Personalized Therapeutic Strategies in Lipedema: A Pilot Study

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Conference poster

7. Dietary liposuction through ketogenic diet: a comparison of three approaches

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Clinical/review evidence

8. Ketogenic diet as a potential intervention for lipedema

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Long-term case follow-up

9. Management of Lipedema with Ketogenic Diet: 22-Month Follow-Up

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Systematic review / meta-analysis

10. The Efficacy of Ketogenic Diets (Low Carbohydrate; High Fat) as a Potential Nutritional Intervention for Lipedema: A Systematic Review and Meta-Analysis.

Amato ACM, Amato JLS, Benitti DA · Nutrients · 2024-09-27

Randomized clinical trial

11. Effect of a ketogenic diet on pain and quality of life in patients with lipedema: The LIPODIET pilot study.

Sørlie V, De Soysa AK, Hyldmo ÅA, Retterstøl K, Martins C, Nymo S · Obesity science & practice · 2022-04-21

Review

12. Therapeutic Applications of Ketogenic Diets in Lipedema: A Narrative Review of Current Evidence.

Sanlier N, Baltacı S · Current obesity reports · 2025-05-26

Case report / case series

13. A Case Series on Combining Modified Mediterranean Diet and Ketogenic Diet in a "Sandwich" Approach for Patients with Lipedema and Comorbidities.

Fedre B, Dessalvi S, Boccardo F · Lymphology · 2025-12-17

Aging & Chronobiology

Longevity & Healthy Aging Recent peer-reviewed literature

Source-audited selection from the connected PDF archive. Systematic reviews/meta-analyses and recent human evidence are prioritized when available; sparse areas are explicitly kept sparse.

Recent review · 2026

1. Ketogenic Diet, Cardiometabolic Diseases and Aging

Original publication title: Ketogenic Diet, Cardiometabolic Diseases and Aging

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Recent review · 2026

2. Dietary Interventions for Healthy Aging: An Epigenetic Perspective

Original publication title: Dietary Interventions for Healthy Aging: An Epigenetic Perspective

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Preclinical aging study · 2025

3. β-Hydroxybutyrate Acts as an Exercise Mimetic to Protect the Aging Liver

Original publication title: β-Hydroxybutyrate Acts as an Exercise Mimetic to Protect the Aging Liver

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Bibliometric review · 2025

4. Relationship Between Aging and Ketogenic Diet: A Bibliometric Analysis (1995–2025)

Original publication title: Relationship Between Aging and Ketogenic Diet: A Bibliometric Analysis (1995–2025)

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Mechanistic aging study · 2025

5. Ketone Catabolism Is Essential for Maintaining Normal Heart Function During Aging

Original publication title: Ketone Catabolism Is Essential for Maintaining Normal Heart Function During Aging

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Scoping review

6. Molecular Mechanisms of Healthy Aging: The Role of Caloric Restriction, Intermittent Fasting, Mediterranean Diet, and Ketogenic Diet—A Scoping Review

Original publication title: Molecular Mechanisms of Healthy Aging: The Role of Caloric Restriction, Intermittent Fasting, Mediterranean Diet, and Ketogenic Diet—A Scoping Review

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Human / clinical or translational evidence

7. Intermittent Fasting, Calorie Restriction, and a Ketogenic Diet Improve Healthspan

Original publication title: Intermittent Fasting, Calorie Restriction, and a Ketogenic Diet Improve Healthspan

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Human / clinical or translational evidence

8. Divergent Sex-Specific Effects of a Ketogenic Diet during Aging

Original publication title: Divergent Sex-Specific Effects of a Ketogenic Diet during Aging

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Mechanistic / preclinical

9. Differential Effects of Short-Term Standard and Ketogenic Diets on the Aging Mouse Brain

Original publication title: Differential Effects of Short-Term Standard and Ketogenic Diets on the Aging Mouse Brain

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Physiological review

10. The central benefit of physiologically induced ketogenic states

Original publication title: The central benefit of physiologically induced ketogenic states

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Review

11. Beneficial Effects of Exogenous Ketogenic Supplements on Aging Processes and Age-Related Neurodegenerative Diseases

Original publication title: Beneficial Effects of Exogenous Ketogenic Supplements on Aging Processes and Age-Related Neurodegenerative Diseases

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Clinical trial / intervention

12. Epigenetic ageing is accelerated in drug-resistant epilepsy and dynamically modulated during ketogenic diet therapy.

Gervin K, Kverneland M, Nakken KO, Rudi K, Iversen PO, Selmer KK · EBioMedicine · 2026-08-22

Observational human study

13. Continuing Ketogenic Diet Therapy in Setting of Hypercalcemia.

Sarabia L, Wetzel A, Sawyer J, Giannini S, Imel E, Delima SI · Journal of child neurology · 2026-07-30

Preclinical / mechanistic

14. Effects of aging in combination with high-fat or ketogenic diet on skeletal muscle hypertrophy after functional overloading in C57BL/6J mice.

Dirmontas M, Minderis P, Ratkevicius A · Growth factors (Chur, Switzerland) · 2026-07-19

Clinical trial / intervention

15. Incidence and risk factors of ketogenic diet-associated nephrolithiasis in children with drug-resistant epilepsy: A tertiary care center experience.

Amer F, Alotaibi W, Bashir S, AlBaradie R, Al Hany E, Ali M, Alamri A, Mir A · Epilepsy research · 2026-07-13

Randomized clinical trial

16. Determinants of Adherence to a Ketogenic Diet in Patients with Heart Failure with Reduced Ejection Fraction.

Liao LP, Murphy B, Gan GCH, Thomas L, Fontana L, McKinn S, Zaman S · Nutrients · 2026-06-09

Other

17. A price check on the ketogenic diet for adults with epilepsy in Australia.

King L, Maccarrone J, Kaur A, Chen S, Kwan P, O'Brien TJ, Kaul N · Epilepsia open · 2026-05-25

Preclinical / mechanistic

18. Fourier Transform Infrared Imaging Supported by Raman Spectroscopy Reveals Biochemical Changes in Adult Rat Brains Following Prenatal Exposure to a Ketogenic Diet.

Rugiel M, Setkowicz Z, Drozdz A, Wilk A, Brylowska Z, Chwiej J · ACS chemical neuroscience · 2026-05-19

Clinical trial / intervention

19. The Ketogenic Diet and Potential Micronutrient Risks in Drug-Resistant Epilepsy Management: A Literature Review.

Singh B, Botten P, Richardson KP, Weaver C, Purohit S · Nutrients · 2026-03-27

Systematic review / meta-analysis

20. Exploring Non-pharmacological Hypertension Management: DASH, Paleolithic, and Ketogenic Diet Comparisons: A Systematic Review.

Wal P, Rath D, Verma N, Wal A, Bhukta P, Natania A, Ved A, Samathoti P, Gasmi A · Current hypertension reviews · 2026-03-26

Preclinical / mechanistic

21. Ketogenic diet causes bone loss in growing and adult mice and reduces the skeletal response to exercise.

Osipov B, Robison L, Hanel J, Orr SV, Lin YY, Buxton A, Rahmati M, Tseng MC, Renato MR, Shenoy R, Bhat AS, Saiz A, Ferguson VL, Loots GG, Christiansen BA · Bone · 2026-03-09

Clinical trial / intervention

22. Sex-dependent protective effects of a ketogenic diet following prenatal stress exposure: Evidence from adolescent rats.

Begni V, Marchesin A, Orso R, Creutzberg KC, Precetti F, Cattaneo A, Riva MA · Brain, behavior, and immunity · 2026-01-19

Observational human study

23. Managing GLUT 1 Deficiency with the Ketogenic Diet: A Retrospective Look at Seizures, Medications, and Side Effects in a Pediatric Cohort.

Morris S, Blackford R, Lowman W, Fisher B · Journal of child neurology · 2026-01-09

Observational human study

24. Weaning from ketogenic diet therapy in children with epilepsy: Insights from a retrospective study.

Donnard N, Dozières-Puyravel B, Geraldes K, Perrot C, Quéméner V, Goujon E, Truchy P, Nasser H, Mauvais FX, Danse M, Auvin S · Epilepsia · 2025-12-24

Preclinical / mechanistic

25. Primary components of MCT ketogenic diet are detrimental to bone loss associated with accelerated aging and age-related neurotoxicity in mice.

Jain S, Vohora D · Bone · 2024-12-26

Preclinical / mechanistic

26. Differential effects of short-term and long-term ketogenic diet on gene expression in the aging mouse brain.

Stratton MS, López-Domínguez JA, Canella A, Ramsey JJ, Cortopassi GA · The journal of nutrition, health & aging · 2024-12-10

Preclinical / mechanistic

27. Ketogenic diet administration later in life improves memory by modifying the synaptic cortical proteome via the PKA signaling pathway in aging mice.

Acuña-Catalán D, Shah S, Wehrfritz C, Nomura M, Acevedo A, Olmos C, Quiroz G, Huerta H, Bons J, Ampuero E, Wyneken U, Sanhueza M, Arancibia F, Contreras D, Cárdenas JC, Morales B, Schilling B, Newman JC, González-Billault C · Cell reports. Medicine · 2024-06-05

Other

28. Standardized ketogenic dietary preparation for metabolic PET imaging in suspected and known cardiac sarcoidosis.

Hutt E, Goldar G, Jaber WA, Cremer PC · European heart journal. Imaging methods and practice · 2024-05-09

Other

29. Evaluating the efficacy of a ketogenic diet in managing drug resistant paediatric DEDPC5-related epilepsy.

Winczewska-Wiktor A, Braszka M, Harada-Laszlo M, Badura-Stronka M, Kaczmarek I, Starczewska M, Wencel-Warot A, Steinborn B, Jamsheer A · Epilepsy & behavior : E&B · 2023-12-19

Preclinical / mechanistic

30. A ketogenic diet reduces age-induced chronic neuroinflammation in mice Running title: ketogenic diet and brain inflammaging.

Nomura M, Murad NF, Madhavan SS, Eap B, Garcia TY, Aguirre CG, Verdin E, Ellerby L, Furman D, Newman JC · bioRxiv : the preprint server for biology · 2023-12-04

Systematic review / meta-analysis

31. Mediterranean Diet, Ketogenic Diet or MIND Diet for Aging Populations with Cognitive Decline: A Systematic Review.

Devranis P, Vassilopoulou Ε, Tsironis V, Sotiriadis PM, Chourdakis M, Aivaliotis M, Tsolaki M · Life (Basel, Switzerland) · 2023-01-06

Other

32. Ketogenic Diets and Mitochondrial Function: Benefits for Aging But Not for Athletes.

Pathak SJ, Baar K · Exercise and sport sciences reviews · 2022-09-16

Review

33. Ketogenic Diet: A Promising Neuroprotective Composition for Managing Alzheimer's Diseases and its Pathological Mechanisms.

Sridharan B, Lee MJ · Current molecular medicine · 2021-04-06

Preclinical / mechanistic

34. Ketogenic diet restrains aging-induced exacerbation of coronavirus infection in mice.

Ryu S, Shchukina I, Youm YH, Qing H, Hilliard B, Dlugos T, Zhang X, Yasumoto Y, Booth CJ, Fernández-Hernando C, Suárez Y, Khanna K, Horvath TL, Dietrich MO, Artyomov M, Wang A, Dixit VD · eLife · 2021-06-21

Clinical trial / intervention

35. The ketogenic diet preserves skeletal muscle with aging in mice.

Wallace MA, Aguirre NW, Marcotte GR, Marshall AG, Baehr LM, Hughes DC, Hamilton KL, Roberts MN, Lopez-Dominguez JA, Miller BF, Ramsey JJ, Baar K · Aging cell · 2021-03-06

Preclinical / mechanistic

36. Ketogenic diet attenuates aging-associated myocardial remodeling and dysfunction in mice.

Yu Y, Wang F, Wang J, Zhang D, Zhao X · Experimental gerontology · 2020-08-16

Randomized clinical trial

37. Cognitive Effects of a Ketogenic Diet on Neurocognitive Impairment in Adults Aging With HIV: A Pilot Study.

Morrison SA, Fazeli PL, Gower B, Willig AL, Younger J, Sneed NM, Vance DE · The Journal of the Association of Nurses in AIDS Care : JANAC · 2019-11-15

Review

38. Consideration of Ketogenic Metabolic Therapy as a Complementary or Alternative Approach for Managing Breast Cancer.

Seyfried TN, Mukherjee P, Iyikesici MS, Slocum A, Kalamian M, Spinosa JP, Chinopoulos C · Frontiers in nutrition · 2020-03-11

Case report / case series

39. The challenges in managing perioperative hypoglycemia in a child on modified Atkins diet.

Mak W, Xu K, Lim SW, Hee HI · Paediatric anaesthesia · 2019-02-06

Preclinical / mechanistic

40. Effects of a Ketogenic Diet on [18F]FDG-PET Imaging in a Mouse Model of Lung Cancer.

Cussó L, Musteanu M, Mulero F, Barbacid M, Desco M · Molecular imaging and biology · 2018-07-04

Randomized clinical trial

41. Serial MRI Imaging Reveals Minimal Impact of Ketogenic Diet on Established Liver Tumor Growth.

Byrne FL, Hargett SR, Lahiri S, Roy RJ, Berr SS, Caldwell SH, Hoehn KL · Cancers · 2018-09-05

Preclinical / mechanistic

42. A Ketogenic Diet Extends Longevity and Healthspan in Adult Mice.

Roberts MN, Wallace MA, Tomilov AA, Zhou Z, Marcotte GR, Tran D, Perez G, Gutierrez-Casado E, Koike S, Knotts TA, Imai DM, Griffey SM, Kim K, Hagopian K, McMackin MZ, Haj FG, Baar K, Cortopassi GA, Ramsey JJ, Lopez-Dominguez JA · Cell metabolism · 2018-05-03

Preclinical / mechanistic

43. Ketogenic diet-induced extension of longevity in epileptic Kcna1-null mice is influenced by gender and age at treatment onset.

Chun KC, Ma SC, Oh H, Rho JM, Kim DY · Epilepsy research · 2017-11-21

Other

44. Ageing: Improvement in age-related cognitive functions and life expectancy by ketogenic diets.

Astrup A, Hjorth MF · Nature reviews. Endocrinology · 2017-11-10

Review

45. Epigenetic mechanisms underlying lifespan and age-related effects of dietary restriction and the ketogenic diet.

Moreno CL, Mobbs CV · Molecular and cellular endocrinology · 2016-11-22

Preclinical / mechanistic

46. Ketogenic Diet Reduces Midlife Mortality and Improves Memory in Aging Mice.

Newman JC, Covarrubias AJ, Zhao M, Yu X, Gut P, Ng CP, Huang Y, Haldar S, Verdin E · Cell metabolism · 2017-01-23

Preclinical / mechanistic

47. Novel ketone body therapy for managing Alzheimer's disease: An Editorial Highlight for Effects of a dietary ketone ester on hippocampal glycolytic and tricarboxylic acid cycle intermediates and amino acids in a 3xTgAD mouse model of Alzheimer's disease.

Puchowicz MA, Seyfried TN · Journal of neurochemistry · 2017-03-15

Preclinical / mechanistic

48. Ketogenic diet treatment increases longevity in Kcna1-null mice, a model of sudden unexpected death in epilepsy.

Simeone KA, Matthews SA, Rho JM, Simeone TA · Epilepsia · 2016-06-27

Preclinical / mechanistic

49. White Matter Lipids as a Ketogenic Fuel Supply in Aging Female Brain: Implications for Alzheimer's Disease.

Klosinski LP, Yao J, Yin F, Fonteh AN, Harrington MG, Christensen TA, Trushina E, Brinton RD · EBioMedicine · 2015-11-03

Preclinical / mechanistic

50. Adaptive changes in amino acid metabolism permit normal longevity in mice consuming a low-carbohydrate ketogenic diet.

Douris N, Melman T, Pecherer JM, Pissios P, Flier JS, Cantley LC, Locasale JW, Maratos-Flier E · Biochimica et biophysica acta · 2015-07-11

Preclinical / mechanistic

51. Early decline in glucose transport and metabolism precedes shift to ketogenic system in female aging and Alzheimer's mouse brain: implication for bioenergetic intervention.

Ding F, Yao J, Rettberg JR, Chen S, Brinton RD · PloS one · 2013-11-11

Review

52. Ketogenic diets: an historical antiepileptic therapy with promising potentialities for the aging brain.

Balietti M, Casoli T, Di Stefano G, Giorgetti B, Aicardi G, Fattoretti P · Ageing research reviews · 2010-02-24

Preclinical / mechanistic

53. A ketogenic diet increases succinic dehydrogenase activity in aging cardiomyocytes.

Balietti M, Fattoretti P, Giorgetti B, Casoli T, Di Stefano G, Solazzi M, Platano D, Aicardi G, Bertoni-Freddari C · Annals of the New York Academy of Sciences · 2009-09-03

Clinical trial / intervention

54. Changing chronomics of clock, immune and Parkinson's disease-associated genes in SCN and SN with aging in male Wistar rats: ketogenic diet intervention.

Sharma SA, Jagota A · Biogerontology · 2025-12-08

Observational human study

55. Higher dietary ketogenic ratio is associated with accelerated biological aging among US adults: analysis from NHANES 2005-2018.

Zheng X, Gong H, Zhang R, Wang J, Cai G, Chen X · Nutrition research (New York, N.Y.) · 2025-09-17

Preclinical / mechanistic

56. Sex-dependent effects of a gestational ketogenic diet on offspring birth and lifespan.

Zala SM, Santos R, Strasser E, Schadde A, Kugler S, Strauss V, Kübber-Heiss A, Zala D · PloS one · 2025-07-17

Clinical trial / intervention

57. Epigenetic Aging Acceleration in Obesity Is Slowed Down by Nutritional Ketosis Following Very Low-Calorie Ketogenic Diet (VLCKD): A New Perspective to Reverse Biological Age.

Izquierdo AG, Lorenzo PM, Costa-Fraga N, Primo-Martin D, Rodriguez-Carnero G, Nicoletti CF, Martínez JA, Casanueva FF, de Luis D, Diaz-Lagares A, Crujeiras AB · Nutrients · 2025-03-18

Circadian Rhythms Recent peer-reviewed literature

Source-audited selection from the connected PDF archive. Systematic reviews/meta-analyses and recent human evidence are prioritized when available; sparse areas are explicitly kept sparse.

Recent study/review

1. Ketogenic Interventions Enhance Circadian and Metabolic Regulation

Original publication title: Ketogenic Interventions Enhance Circadian and Metabolic Regulation

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Scoping review

2. The Effects of Ketogenic Dietary Therapies on Sleep: A Scoping Review

Original publication title: The Effects of Ketogenic Dietary Therapies on Sleep: A Scoping Review

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Human clinical study

3. Can the Ketogenic Diet Improve Our Dreams? Effect of VLCKD on Sleep Quality

Original publication title: Can the Ketogenic Diet Improve Our Dreams? Effect of VLCKD on Sleep Quality

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Mechanistic review

4. The Influence of Ketone Bodies on Circadian Processes

Original publication title: The Influence of Ketone Bodies on Circadian Processes

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Review

5. Sleep, Mood Disorders, and the Ketogenic Diet: Potential Therapeutic Targets for Bipolar Disorder and Schizophrenia

Original publication title: Sleep, Mood Disorders, and the Ketogenic Diet: Potential Therapeutic Targets for Bipolar Disorder and Schizophrenia

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Preclinical sleep study

6. Ketogenic Diet Affects Sleep Architecture in C57BL/6J Wild Type and Fragile X Mice

Original publication title: Ketogenic Diet Affects Sleep Architecture in C57BL/6J Wild Type and Fragile X Mice

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Review

7. Epilepsy, Gut Microbiota, and Circadian Rhythm

Original publication title: Epilepsy, Gut Microbiota, and Circadian Rhythm

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Randomized clinical trial

8. Supplementation With Ketogenic Precursors Enhances Virtual Reality Shooting Performance During Sleep Restriction: A Randomized, Placebo-Controlled, Crossover Trial.

Buga A, Stoner JT, Sapper TN, Crabtree CD, Decker DD, Robinson BT, Kackley ML, McClure T, Chebbi A, Stalter H, Dawson L, Whiteman A, Spencer M, Lane L, Hayes SM, Mindel J, Kraemer WJ, Volek JS · Military medicine · 2026-09-17

Other

9. Ketone Ester Intake Did Not Improve Performance, Neither Cognitive Function or Sleep, During an 8-Day Simulated Cycling Race.

Engelbrecht L, Lauriks W, Robberechts R, Stalmans M, Ramaekers M, Terblanche E, Koppo K, Poffé C · Medicine and science in sports and exercise · 2026-08-27

Randomized clinical trial

10. Five-year patient-reported outcomes of individualized nutrition therapy supporting nutritional ketosis in adults with type 2 diabetes.

Adams RN, Athinarayanan SJ, Phinney SD, Volek JS, McKenzie AL · Frontiers in nutrition · 2026-08-14

Observational human study

11. Ketogenic diet for pediatric drug-resistant epilepsy: sleep, children's psychosocial functioning, and maternal mental health.

Nassar MF, El-Rashidy OF, Shata MO, ElHagaar MA, Abdelmageed RI · Pediatric research · 2026-07-28

Clinical trial / intervention

12. Hypomanic symptoms and first manic episode during ketogenic diet treatment in a patient taking venlafaxine: a case report with longitudinal glucose-ketone index and clinical monitoring.

Pou-Álvarez M, Casanovas F, Córcoles D, León-Caballero J, Sabaté A, González-Fresnedo AM, Samos P, Perez-Sola V, Martín LM · Frontiers in nutrition · 2026-07-16

Observational human study

13. Neurodevelopmental Risk Factors and Comparative Efficacy of Ketogenic Diet in Children With Spike-Wave Activation in Sleep: A Cohort Study.

Ma J, Wang J, Song X, Xie L, Li X, Hu Y, Hong S, Jiang L, Li T · Pediatric neurology · 2026-07-08

Clinical trial / intervention

14. Telehealth-Based Ketogenic Metabolic Therapy With Lifestyle Interventions for Post-viral Illness: A Research Brief of Patients' Experiences.

Colgan DD, Stadler DD, Grow T, Ruddick M, Weimbs T, Davenport TE, Zwickey H · Journal of patient experience · 2026-07-05

Observational human study

15. Six- and Twelve-Month Changes in Body Composition and 24-h Energy Expenditure After a Very Low-Calorie Ketogenic Diet.

Basolo A, Piaggi P, Angeli V, Fierabracci P, Bologna C, Paolucci G, Salvetti G, Chiovato L, Krakoff J, Landi A, Santini F · Obesity (Silver Spring, Md.) · 2026-06-15

Observational human study

16. Early Electroencephalographic Changes After Ketogenic Diet Initiation Are Associated With Clinical Response in Pediatric Drug-Resistant Epilepsy.

Yavuz M, Unalp A, Gulagız F, Guzin Y, Yılmaz U · Seizure · 2026-06-10

Clinical trial / intervention

17. Ketogenic interventions enhance REM sleep in females and support memory in aged rats.

Lark ARS, Mir FA, Ambareen N, Tian F, Carpenter AH, Crowley EA, Toro BA, Syme CE, Aygar S, Thendral A, Smith K, White CG, Mahamdeh MS, Choi J, Nehs CJ · Frontiers in aging neuroscience · 2026-04-10

Clinical trial / intervention

18. Ketogenic diet attenuates late gestational sleep deprivation-induced aggression in adult offspring mice.

Zhou F, Yu X, Gong M, Yin X, Li Y, Sang Y, Liu X, Liu Y, Yan S, Song L, Zhao Y, Shi H · Physiology & behavior · 2026-03-26

Clinical trial / intervention

19. Ketogenic metabolic therapy as a candidate adjunct for CBTp delivery in schizophrenia spectrum disorders.

Laurent N · Frontiers in psychology · 2026-03-25

Clinical trial / intervention

20. Impaired hepatic BMAL1-FGF21 signaling drives adverse metabolic outcomes of ketogenic diet.

Yang M, Guo Y, Du J, Li C, Bai H, Guo Y, Tan Y, Li X, Ren D, Li J, Zhang X, Zhang P, Wu G · Life sciences · 2026-03-18

Other

21. Ketogenic Diet Improves Sleep Quality and Daytime Sleepiness in Chronic Migraine: A Pilot Study.

Tereshko Y, Dal Bello S, Belgrado E, Di Lorenzo C, Pittino A, Filippi F, Valdemarin F, Lettieri C, Gigli GL, Nilo A, Pellitteri G, Merlino G, Valente M · Neurology international · 2024-10-25

Clinical trial / intervention

22. Impact of a ketogenic diet on sleep quality in people with relapsing multiple sclerosis.

Perlman J, Wetmore E, Lehner-Gulotta D, Banwell B, Bergqvist AGC, Coleman R, Chen S, Conaway M, Goldman MD, Morse AM, Brenton JN · Sleep medicine · 2024-08-28

Other

23. The Liver Circadian Metabolic Homeostasis Influence by Combining Ketogenic Diet with Exercise.

Xu W, Wang Z, Zhang C, Yang W, Fan L, Sun H · Nutrients · 2024-06-27

Clinical trial / intervention

24. Adult Inception of Ketogenic Diet Therapy Increases Sleep during the Dark Cycle in C57BL/6J Wild Type and Fragile X Mice.

Westmark PR, Swietlik TJ, Runde E, Corsiga B, Nissan R, Boeck B, Granger R, Jennings E, Nebbia M, Thauwald A, Lyon G, Maganti RK, Westmark CJ · International journal of molecular sciences · 2024-06-18

Observational human study

25. Sleep effects of Ketogenic diet in pediatric patients with migraine: Preliminary data of a prospective study.

Pasca L, Toni F, Fassio F, Dogliani S, Genta S, Grumi S, Sammartano A, Vitali H, Capriglia E, Tagliabue A, Guglielmetti M, De Giorgis V, Carpani A, Terzaghi M · Sleep medicine · 2023-12-07

Other

26. Ketogenic diet may improve sleep quality and daytime somnolence in patients affected by multiple sclerosis. Results of an exploratory study.

Merlino G, Garbo R, Dal Bello S, Del Negro I, Lamon E, Filippi F, Bernardini A, Lorenzut S, Ceccarelli L, Cella A, Marè A, Tereshko Y, Gigli GL, Valente M · Sleep medicine · 2023-10-20

Randomized clinical trial

27. Ketogenic diet acutely improves gas exchange and sleep apnoea in obesity hypoventilation syndrome: A non-randomized crossover study.

Osman A, Gu C, Kim DE, Duan D, Barron B, Pham LV, Polotsky VY, Jun JC · Respirology (Carlton, Vic.) · 2023-05-28

Randomized clinical trial

28. The effect of a 2 week ketogenic diet, versus a carbohydrate-based diet, on cognitive performance, mood and subjective sleepiness during 36 h of extended wakefulness in military personnel: An exploratory study.

Henderson LR, van den Berg M, Shaw DM · Journal of sleep research · 2023-02-03

Other

29. Can the ketogenic diet improve our dreams? Effect of very low-calorie ketogenic diet (VLCKD) on sleep quality.

Barrea L, Verde L, Di Lorenzo C, Savastano S, Colao A, Muscogiuri G · Journal of translational medicine · 2023-07-18

Preclinical / mechanistic

30. A ketogenic diet containing medium-chain triglycerides reduces REM sleep duration without significant influence on mouse circadian phenotypes.

Zhuang H, Fujikura Y, Ohkura N, Higo-Yamamoto S, Mishima T, Oishi K · Food research international (Ottawa, Ont.) · 2023-04-21

Other

31. Sleep of migraine patients is ameliorated by ketogenic diet, independently of pain control.

Merlino G, Tereshko Y, Pez S, Dal Bello S, Pittino A, Di Lorenzo C, Filippi F, Lettieri C, Belgrado E, Gigli GL, Valente M · Sleep medicine · 2023-05-09

Randomized clinical trial

32. Brain glutamate and sleep efficiency associations following a ketogenic diet intervention in individuals with Alcohol Use Disorder.

Li X, Shi Z, Byanyima J, Morgan PT, van der Veen JW, Zhang R, Deneke E, Wang GJ, Volkow ND, Wiers CE · Drug and alcohol dependence reports · 2022-09-08

Randomized clinical trial

33. Cognitive, Sleep, and Autonomic Responses to Induction of a Ketogenic Diet in Military Personnel: A Pilot Study.

Shaw DM, Henderson L, van den Berg M · Aerospace medicine and human performance · 2022-06-22

Review

34. Is there a relationship between the ketogenic diet and sleep disorders?

Barrea L, Pugliese G, Frias-Toral E, Napolitano B, Laudisio D, Aprano S, Ceriani F, Savastano S, Colao A, Muscogiuri G · International journal of food sciences and nutrition · 2021-10-26

Systematic review / meta-analysis

35. The Influence of Ketone Bodies on Circadian Processes Regarding Appetite, Sleep and Hormone Release: A Systematic Review of the Literature.

Masi D, Spoltore ME, Rossetti R, Watanabe M, Tozzi R, Caputi A, Risi R, Balena A, Gandini O, Mariani S, Spera G, Gnessi L, Lubrano C · Nutrients · 2022-03-28

Preclinical / mechanistic

36. A comparative study of the effect of a gentle ketogenic diet containing medium-chain or long-chain triglycerides on chronic sleep deprivation-induced cognitive deficiency.

Wang X, Yang Y, Xiao A, Zhang N, Miao M, Wang Z, Han J, Wen M · Food & function · 2022-02-21

Review

37. Chronobiology and Metabolism: Is Ketogenic Diet Able to Influence Circadian Rhythm?

Gangitano E, Gnessi L, Lenzi A, Ray D · Frontiers in neuroscience · 2021-11-08

Review

38. The therapeutic properties of ketogenic diets, slow-wave sleep, and circadian synchrony.

O'Hearn LA · Current opinion in endocrinology, diabetes, and obesity · 2021-07-17

Case report / case series

39. Usefulness of Continuous Glucose Monitoring for Prevention and Early Detection of Hypoglycemia Caused by a Ketogenic Diet and Late Dumping Syndrome.

Morikawa M, Hara Y, Nakazawa Y, Inaba Y, Motobayashi M · Pediatric neurology · 2019-12-26

Randomized clinical trial

40. Three consecutive weeks of nutritional ketosis has no effect on cognitive function, sleep, and mood compared with a high-carbohydrate, low-fat diet in healthy individuals: a randomized, crossover, controlled trial.

Iacovides S, Goble D, Paterson B, Meiring RM · The American journal of clinical nutrition · 2018-11-29

Randomized clinical trial

41. Effect of A Very Low-Calorie Ketogenic Diet on Food and Alcohol Cravings, Physical and Sexual Activity, Sleep Disturbances, and Quality of Life in Obese Patients.

Castro AI, Gomez-Arbelaez D, Crujeiras AB, Granero R, Aguera Z, Jimenez-Murcia S, Sajoux I, Lopez-Jaramillo P, Fernandez-Aranda F, Casanueva FF · Nutrients · 2018-09-21

Other

42. Metabolism: Ketogenic diet rewires circadian clock.

Greenhill C · Nature reviews. Endocrinology · 2017-09-22

Other

43. Distinct Circadian Signatures in Liver and Gut Clocks Revealed by Ketogenic Diet.

Tognini P, Murakami M, Liu Y, Eckel-Mahan KL, Newman JC, Verdin E, Baldi P, Sassone-Corsi P · Cell metabolism · 2016-10-27

Preclinical / mechanistic

44. Ketogenic diet induces expression of the muscle circadian gene Slc25a25 via neural pathway that might be involved in muscle thermogenesis.

Nakao R, Shimba S, Oishi K · Scientific reports · 2017-06-06

Review

45. How effective is the ketogenic diet for electrical status epilepticus of sleep?

Kelley SA, Kossoff EH · Epilepsy research · 2016-09-23

Preclinical / mechanistic

46. Ketogenic diet delays the phase of circadian rhythms and does not affect AMP-activated protein kinase (AMPK) in mouse liver.

Genzer Y, Dadon M, Burg C, Chapnik N, Froy O · Molecular and cellular endocrinology · 2015-09-25

Observational human study

47. Ketogenic diet in patients with epileptic encephalopathy with electrical status epilepticus during slow sleep.

Reyes G, Flesler S, Armeno M, Fortini S, Ariela A, Cresta A, Mestre G, Caraballo RH · Epilepsy research · 2015-04-09

Preclinical / mechanistic

48. PPARα deficiency augments a ketogenic diet-induced circadian PAI-1 expression possibly through PPARγ activation in the liver.

Oishi K, Uchida D, Ohkura N, Horie S · Biochemical and biophysical research communications · 2010-09-18

Preclinical / mechanistic

49. Ketogenic diet disrupts the circadian clock and increases hypofibrinolytic risk by inducing expression of plasminogen activator inhibitor-1.

Oishi K, Uchida D, Ohkura N, Doi R, Ishida N, Kadota K, Horie S · Arteriosclerosis, thrombosis, and vascular biology · 2009-07-23

Case report / case series

50. Rational treatment options with AEDs and ketogenic diet in Landau-Kleffner syndrome: still waiting after all these years.

Lagae L · Epilepsia · 2009-08-18

Observational human study

51. Ketogenic diet in the treatment of refractory continuous spikes and waves during slow sleep.

Nikanorova M, Miranda MJ, Atkins M, Sahlholdt L · Epilepsia · 2009-02-12

Other

52. Ketogenic diet improves sleep quality in children with therapy-resistant epilepsy.

Hallböök T, Lundgren J, Rosén I · Epilepsia · 2007-01-24

Other

53. The effects of a high-protein, low-fat, ketogenic diet on adolescents with morbid obesity: body composition, blood chemistries, and sleep abnormalities.

Willi SM, Oexmann MJ, Wright NM, Collop NA, Key LL · Pediatrics · 1998-01-17

Randomized clinical trial

54. Modified atkins diet in children with developmental and epileptic encephalopathy with spike-wave activation in sleep (D/EE-SWAS): A prospective interventional, non-randomized, single-arm study.

Singh S, Saini AG, Puri D, Pattanaik S, Sharma R, Malhi P, Suthar R, Sahu JK, Sankhyan N · Seizure · 2025-11-06

Clinical trial / intervention

55. A ketogenic diet decreases sevoflurane-induced burst suppression in rats.

Siegmann MJ, Parry S, Lark ARS, Mir FA, Choi J, Carpenter AH, Crowley EA, White CG, Kang J, Purdon PL, Nehs CJ · Brain research bulletin · 2025-02-24

Gut & Microbiome

Gut Microbiome Recent peer-reviewed literature

Evidence is ordered preferentially by systematic reviews/meta-analyses and recent high-level evidence, followed by recent clinical studies and then relevant mechanistic work.

Systematic review & meta-analysis · 2025

1. The impact of very-low-calorie ketogenic diets on gut microbiota in individuals with obesity: a systematic review and meta-analysis

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Recent review · 2026

2. How the Ketogenic Diet Shapes the Microbiome to Influence Cancer Immunotherapy Outcomes: An Exploration of Clinical Trials and Their Results

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Human clinical study · 2026

3. The effects of a very low-energy ketogenic therapy on body composition, gut microbiota and metabolites in overweight subjects

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Human VLEKT study · 2026

4. Time Exposure and Fat Mass Reduction Drive Trimethylamine N-Oxide Modulation During a Very-Low-Energy Ketogenic Therapy (VLEKT) in Women with Obesity

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Recent disease-focused review · 2026

5. Exploring the role of gut microbiota in potential mechanism of ketogenic diet in alleviating Parkinson’s disease symptoms

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Recent review · 2025

6. Ketogenic Diet and Gut Microbiota: Exploring New Perspectives on Cognition and Mood

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Human multi-omics study

7. A Multi-Omics Approach to Disclose Metabolic Pathways Impacting Intestinal Permeability in Obese Patients Undergoing Very Low Calorie Ketogenic Diet

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Review

8. The Influence of Ketogenic Diet on Gut Microbiota: Potential Benefits, Risks and Indications

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Review

9. Does the ketogenic diet improve neurological disorders by influencing gut microbiota?

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Human intervention

10. Weight Loss Promotion in Individuals with Obesity through Gut Microbiota Alterations with a Multiphase Modified Ketogenic Diet

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Clinical pediatric study

11. Effects of ketogenic diet on the classification and functional composition of intestinal flora in children with mitochondrial epilepsy

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Human VLCKD study

12. The Impact of a Very-Low-Calorie Ketogenic Diet in the Gut Microbiota Composition in Obesity

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Review

13. Regulation of gut microbiome by ketogenic diet in neurodegenerative diseases: A molecular crosstalk

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Review

14. The Potential Roles of Very Low Calorie, Very Low Calorie Ketogenic Diets and Very Low Carbohydrate Diets on the Gut Microbiota Composition

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Review

15. Ketogenic Diet and Microbiota

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Human / clinical or translational evidence

16. Ketogenic Diet, Gut Microbiome and Cancer Immunotherapy Outcomes

Original publication title: Ketogenic Diet, Gut Microbiome and Cancer Immunotherapy Outcomes

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Human / clinical or translational evidence

17. Very Low-Energy Ketogenic Therapy and Trimethylamine N-Oxide in Women with Obesity

Original publication title: Very Low-Energy Ketogenic Therapy and Trimethylamine N-Oxide in Women with Obesity

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Human / clinical or translational evidence

18. Parkinson’s Disease, Gut Microbiota and Ketogenic Diet

Original publication title: Parkinson’s Disease, Gut Microbiota and Ketogenic Diet

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Position statement

19. The Effects of Very Low-Energy Ketogenic Therapy on Body Composition, Gut Microbiota and Metabolites

Original publication title: The Effects of Very Low-Energy Ketogenic Therapy on Body Composition, Gut Microbiota and Metabolites

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Systematic review & meta-analysis

20. Very-Low-Calorie Ketogenic Diets and Gut Microbiota in Obesity: Systematic Review and Meta-Analysis

Original publication title: Very-Low-Calorie Ketogenic Diets and Gut Microbiota in Obesity: Systematic Review and Meta-Analysis

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Human / clinical or translational evidence

21. Ketogenic Diet, Gut Microbiota, Cognition and Mood

Original publication title: Ketogenic Diet, Gut Microbiota, Cognition and Mood

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Human / clinical or translational evidence

22. A Multi-Omics Approach to Intestinal Permeability during a Very Low-Calorie Ketogenic Diet

Original publication title: A Multi-Omics Approach to Intestinal Permeability during a Very Low-Calorie Ketogenic Diet

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Human / clinical or translational evidence

23. Ketogenic Diet, Epilepsy and the Brain-Gut Axis

Original publication title: Ketogenic Diet, Epilepsy and the Brain-Gut Axis

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Human / clinical or translational evidence

24. Fecal Microbiota Transfer from Children on a Ketogenic Diet

Original publication title: Fecal Microbiota Transfer from Children on a Ketogenic Diet

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Human / clinical or translational evidence

25. Ketogenic Diet and Gut Microbiota in Neurological Disorders

Original publication title: Ketogenic Diet and Gut Microbiota in Neurological Disorders

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Human / clinical or translational evidence

26. Modified Ketogenic Diet and Gut Microbiota in Obesity

Original publication title: Modified Ketogenic Diet and Gut Microbiota in Obesity

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Human / clinical or translational evidence

27. Influence of the Ketogenic Diet on Gut Microbiota

Original publication title: Influence of the Ketogenic Diet on Gut Microbiota

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Human / clinical or translational evidence

28. Mitochondrial Epilepsy, Ketogenic Therapy and the Gut Microbiome

Original publication title: Mitochondrial Epilepsy, Ketogenic Therapy and the Gut Microbiome

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Human / clinical or translational evidence

29. Very Low-Calorie Ketogenic Diet and Microbiota in Obesity

Original publication title: Very Low-Calorie Ketogenic Diet and Microbiota in Obesity

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Human / clinical or translational evidence

30. Epilepsy, Gut Microbiota, and Circadian Rhythm

Original publication title: Epilepsy, Gut Microbiota, and Circadian Rhythm

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Human / clinical or translational evidence

31. Ketogenic Diet, Gut Microbiota and Neurodegenerative Disorders

Original publication title: Ketogenic Diet, Gut Microbiota and Neurodegenerative Disorders

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Human / clinical or translational evidence

32. Very Low-Carbohydrate Ketogenic Diet, Gut Microbiota and Short-Chain Fatty Acids

Original publication title: Very Low-Carbohydrate Ketogenic Diet, Gut Microbiota and Short-Chain Fatty Acids

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Human / clinical or translational evidence

33. Ketogenic Diet Intervention via the Gut Microbiota in Autism Spectrum Disorder

Original publication title: Ketogenic Diet Intervention via the Gut Microbiota in Autism Spectrum Disorder

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Human / clinical or translational evidence

34. Very Low-Calorie, Ketogenic and Low-Carbohydrate Diets: Effects on the Gut Microbiota

Original publication title: Very Low-Calorie, Ketogenic and Low-Carbohydrate Diets: Effects on the Gut Microbiota

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Clinical trial / intervention

35. Ketogenic diet-induced changes in hepatic drug metabolism with potential implications for ozanimod pharmacokinetics in mice.

Frybortova V, Satka S, Jourova L, Anzenbacher P, Zapletalova I, Kraus M, Kostovcikova K, Kverka M, Anzenbacherova E · PloS one · 2026-09-08

Randomized clinical trial

36. Ketogenic diet combined with probiotics for polyendocrine metabolic ovarian syndrome: research progress from the perspective of the gut microbiota-host metabolic axis.

Yang Y, Dai F, He X, Zhao P, Chen Q · Frontiers in nutrition · 2026-09-02

Randomized clinical trial

37. Comparison of clinical efficacy and gut microbiota characteristics in children with ASD treated with fecal microbiota transplantation and ketogenic diet.

Wang Y, Wang L, Cai Z, Yu L, Guo Y, Zhang L, Zhu M, Liu Z, Zhao Y, Liu L, Cao A · BMC psychiatry · 2026-09-02

Clinical trial / intervention

38. Effect of Ketogenic Diet Versus Vegan Diet on Obesity-Induced Testicular Dysfunction and Mediating Role of Gut Microbiota.

Salama SA, Hassan NH, Abdelhadi AA, Soliman EK, Soliman AHM, Malek MM, Atia RRA, Mohamed SRA, Wahid IM, Salem IM, Aldisi D, Abulmeaty MMA, Abdal-Hay A, Wahid RM · International journal of molecular sciences · 2026-07-27

Clinical trial / intervention

39. Ketogenic diet alleviates acute radiation-induced intestinal injury through JAK2/STAT3/RORγt/IL-17A signaling pathway via gut microbiome.

Yang J, Ling Z, Zhou M, Tao M, Mao J, Guo H, Wang J, Qu X, Wang Y, Zhu Y, Zhang K, Yan X · Communications biology · 2026-06-30

Review

40. Ketogenic Diet in Obesity and Diabetes: A Narrative Review.

An Y, Norris N, Li D, Gunton JE · Nutrients · 2026-06-20

Other

41. Ketogenic Diet Alleviates Colorectal Cancer by Attenuating Macrophage M2 Polarisation Triggered by Oncometabolite MMA Derived From the Gut Microbiota.

Lu Y, Shi B, Chen J, Yao H, Mi X, Shao M, Zhao Y, Meng L, Tai Q, Chen J, Shi X, Zhou D, Yao Y, He S · Cell proliferation · 2026-06-17

Clinical trial / intervention

42. Ketogenic Diets and Low Carb Diets: The Effects on the Intestinal Microbiota. A Narrative Review.

Bertuccioli A, Sisti D, Palazzi CM, Belli A, Mota JF, Mariotti E, Zonzini GB, Rocchi MBL, Di Pierro F, Moro T, Paoli A · Nutrition reviews · 2026-06-02

Review

43. Ketogenic diet as a therapeutic strategy for neurodegenerative diseases: from mechanisms to translational challenges.

Salgueiro AM, Ferreira-Marques M, Ribeiro RFN, Lopes SM, Pereira D, Costa DG, Santana MM, de Almeida LP, Cavadas C · Translational neurodegeneration · 2026-05-25

Clinical trial / intervention

44. The Ketogenic Diet Fails to Mitigate Seizures and Neuroinflammatory Responses in a Mouse Model of Virus-Induced Epilepsy.

Meili CH, Allen K, Doty DJ, Del Fiol S, DePaula-Silva AB · bioRxiv : the preprint server for biology · 2026-05-21

Preclinical / mechanistic

45. Ketogenic Diet Modulates Depressive-Like Behavior via Gut Bacterial Metabolism of Tyrosine.

Zhang Y, Li X, Zhang X, Wang Y, Chen Z, Lin X, Zheng X, Hao H, Zhang X · FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026-05-14

Observational human study

46. Gut microbiota shifts and short-chain fatty acids alterations in pediatric epilepsy patients on a Mediterranean ketogenic diet.

Zouganeli S, Mitsou EK, Yannakoulia M, Intze E, Mountzouris KC, Fessatou S, Attilakos A, Kyriacou A, Dinopoulos A · Epileptic disorders : international epilepsy journal with videotape · 2026-05-07

Preclinical / mechanistic

47. From gut to brain: short-term ketogenic diet alleviates status epilepticus-induced cognitive deficits in rats.

Chen Y, Xu W, Hou Q, Jiang Y · Frontiers in physiology · 2026-04-28

Clinical trial / intervention

48. Metabolic and gut microbiota effects of ketogenic diet and exogenous ketone salts in a rat model of metabolic syndrome.

Pereira-Rodrigues A, Gonçalves A, Alves IN, Mendes CS, Silva C, Campos J, Sampaio-Maia B, Falcão-Pires I, Araujo R · European journal of nutrition · 2026-04-28

Preclinical / mechanistic

49. Ketogenic diet-derived faecal microbiota transplantation improved sensorimotor gating deficits in an acute NMDA-receptor antagonist model of schizophrenia in mice.

Kraeuter AK, Sarnyai Z · Food & function · 2026-04-27

Clinical trial / intervention

50. Ketogenic diet modulates gut microbiota composition in an experimental model of cerebral palsy.

Dantas Alves JS, De Oliveira Melo NC, Toscano AE, Manhães-De-Castro R, Fraga Filho CX, Cruz Neto JPR, De Brito Alves JL, Muniz GS · Nutritional neuroscience · 2026-04-24

Other

51. Ketogenic diet synergistic reprogramming of both host and microbiome promotes tissue regeneration.

Nagai M, Band V, Chi L, Smelkinson M, Schwarz B, Brandes NT, Burns A, Perez-Chaparro PJ, McCauley KE, Corral D, Bouladoux N, Link VM, Zheng L, Constantinides MG, Otto M, Moutsopoulos NM, Belkaid Y · bioRxiv : the preprint server for biology · 2026-04-13

Review

52. Rewiring the brain: Ketogenic diet and gut microbiota in nervous system development.

Jędrusik J, Setkowicz Z · Nutrition (Burbank, Los Angeles County, Calif.) · 2026-01-10

Randomized clinical trial

53. A randomized phase II trial of gemcitabine, nab-paclitaxel, cisplatin with or without a medically supervised ketogenic diet for patients with metastatic pancreatic cancer.

Jameson GS, Roe DJ, Borazanci E, Hanna DL, Roberts CGP, Pelster MS, Frank RC, Alistar AT, Miller AM, Wiedmeier-Nutor JE, Algaze SD, Zoller AR, Hallberg SJ, Wertheim BC, Lee K, Cridebring D, Rabinowitz JD, Gately S, Keppler J, Sharma S, Von Hoff DD, Rasco DW · Cancer · 2025-12-05

Clinical trial / intervention

54. Nutritional Strategies in Major Depression Disorder: From Ketogenic Diet to Modulation of the Microbiota-Gut-Brain Axis.

Nikdasti A, Khodadadi ES, Ferdosi F, Dadgostar E, Yahyazadeh S, Heidari P, Ehtiati S, Vakili O, Khatami SH · Molecular neurobiology · 2024-08-28

Randomized clinical trial

55. KETO-MOOD: Ketogenic Diet for Microbiome Optimization and Overcoming Depression - A Protocol for a Randomized Controlled Trial.

Hongler K, Lounici A, Maurer E, Lanz U, Szathmari O, Reuter Y, Nussbaum S, Steinborn I, Haedrich A, Mölling MA, Wein U, Bocek I, Hersberger L, Brühl AB, Lang UE, Liwinski T · Neuroimmunomodulation · 2024-12-19

Preclinical / mechanistic

56. Analysis of the brain transcriptome, microbiome and metabolome in ketogenic diet and experimental stroke.

Zharikova AA, Andrianova NV, Silachev DN, Nebogatikov VO, Pevzner IB, Makievskaya CI, Zorova LD, Maleev GV, Baydakova GV, Chistyakov DV, Goriainov SV, Sergeeva MG, Burakova IY, Gureev AP, Popkov VA, Ustyugov AA, Plotnikov EY · Brain, behavior, and immunity · 2024-10-06

Clinical trial / intervention

57. Effects of the Ketogenic Diet on Microbiota Composition and Short-Chain Fatty Acids in Women with Overweight/Obesity.

Güzey Akansel M, Baş M, Gençalp C, Kahrıman M, Şahin E, Öztürk H, Gür G, Gür C · Nutrients · 2024-12-19

Review

58. Ketogenic diet as a therapeutic approach in autism spectrum disorder: a narrative review.

Öztürk E, Aslan Çin NN, Cansu A, Akyol A · Metabolic brain disease · 2024-12-18

Clinical trial / intervention

59. Gut Microbiota Modulates Fgf21 Expression and Metabolic Phenotypes Induced by Ketogenic Diet.

Wei X, Lu Y, Hong S · Nutrients · 2024-11-25

Preclinical / mechanistic

60. Generalized Ketogenic Diet Induced Liver Impairment and Reduced Probiotics Abundance of Gut Microbiota in Rat.

Song G, Song D, Wang Y, Wang L, Wang W · Biology · 2024-11-04

Clinical trial / intervention

61. A Ketogenic Diet Affects Gut Microbiota by Regulating Gut Microbiota and Promoting Hippocampal TRHR Expression to Combat Seizures.

Xiong W, Lin X, Lin X, Wu L, Lin W · Journal of molecular neuroscience : MN · 2024-11-03

Preclinical / mechanistic

62. Ketogenic Diets Alter the Gut Microbiome, Resulting in Decreased Susceptibility to and Cognitive Impairment in Rats with Pilocarpine-Induced Status Epilepticus.

Li B, Ma Y, Wang X, Zhao D, Wang Z, Wang G, Li C, Yang L, Ji H, Liu K, Chen Q, Yang Y, Ma W, Du J, Ma L, Zhang L, Qiang Y · Neurochemical research · 2024-06-27

Preclinical / mechanistic

63. The gut microbiota changed by ketogenic diets contribute to glucose intolerance rather than lipid accumulation.

Li W, Gong M, Wang Z, Pan H, Li Y, Zhang C · Frontiers in endocrinology · 2024-09-27

Preclinical / mechanistic

64. The ketogenic diet mitigates opioid-induced hyperalgesia by restoring short-chain fatty acids-producing bacteria in the gut.

Crawford J, Liu S, Tao R, Kramer P, Bender S, Tao F · Pain · 2024-03-06

Randomized clinical trial

65. Ketogenic diet but not free-sugar restriction alters glucose tolerance, lipid metabolism, peripheral tissue phenotype, and gut microbiome: RCT.

Hengist A, Davies RG, Walhin JP, Buniam J, Merrell LH, Rogers L, Bradshaw L, Moreno-Cabañas A, Rogers PJ, Brunstrom JM, Hodson L, van Loon LJC, Barton W, O'Donovan C, Crispie F, O'Sullivan O, Cotter PD, Proctor K, Betts JA, Koumanov F, Thompson D, Gonzalez JT · Cell reports. Medicine · 2024-08-05

Preclinical / mechanistic

66. Living Conditions Alter Ketogenic Diet-induced Metabolic Consequences in Mice through Modulating Gut Microbiota.

Yang J, Li X, Dai C, Teng Y, Xie L, Tian H, Hong S · Phenomics (Cham, Switzerland) · 2024-06-06

Randomized clinical trial

67. Intermittent fasting, calorie restriction, and a ketogenic diet improve mitochondrial function by reducing lipopolysaccharide signaling in monocytes during obesity: A randomized clinical trial.

Guevara-Cruz M, Hernández-Gómez KG, Condado-Huerta C, González-Salazar LE, Peña-Flores AK, Pichardo-Ontiveros E, Serralde-Zúñiga AE, Sánchez-Tapia M, Maya O, Medina-Vera I, Noriega LG, López-Barradas A, Rodríguez-Lima O, Mata I, Olin-Sandoval V, Torres N, Tovar AR, Velázquez-Villegas LA · Clinical nutrition (Edinburgh, Scotland) · 2024-07-05

Preclinical / mechanistic

68. Dietary fiber content in clinical ketogenic diets modifies the gut microbiome and seizure resistance in mice.

Özcan E, Yu KB, Dinh L, Lum GR, Lau K, Hsu J, Arino M, Paramo J, Lopez-Romero A, Hsiao EY · bioRxiv : the preprint server for biology · 2024-07-31

Preclinical / mechanistic

69. Metagenomic and metabolomic analysis showing the adverse risk-benefit trade-off of the ketogenic diet.

Qiu H, Kan C, Han F, Luo Y, Qu N, Zhang K, Ma Y, Hou N, Wu D, Sun X, Shi J · Lipids in health and disease · 2024-06-29

Clinical trial / intervention

70. Ketogenic Diet Induced Shifts in the Gut Microbiome Associate with Changes to Inflammatory Cytokines and Brain-Related miRNAs in Children with Autism Spectrum Disorder.

Allan NP, Yamamoto BY, Kunihiro BP, Nunokawa CKL, Rubas NC, Wells RK, Umeda L, Phankitnirundorn K, Torres A, Peres R, Takahashi E, Maunakea AK · Nutrients · 2024-05-07

Clinical trial / intervention

71. Differential peripheral immune signatures elicited by vegan versus ketogenic diets in humans.

Link VM, Subramanian P, Cheung F, Han KL, Stacy A, Chi L, Sellers BA, Koroleva G, Courville AB, Mistry S, Burns A, Apps R, Hall KD, Belkaid Y · Nature medicine · 2024-01-30

Systematic review / meta-analysis

72. Does the ketogenic diet improve neurological disorders by influencing gut microbiota? A systematic review.

Mazandarani M, Lashkarbolouk N, Ejtahed HS, Qorbani M · Nutrition journal · 2023-11-20

Other

73. Ketogenic Diets in Children With Intractable Epilepsy and its Effects on Gastrointestinal Function, Gut Microbiome, Inflammation, and Quality of Life.

Menzies J, Sundararaj A, Cardamone M, McHarg A, Leach S, Krishnan U · Journal of pediatric gastroenterology and nutrition · 2023-09-08

Preclinical / mechanistic

74. Ketogenic Diet Has Moderate Effects on the Fecal Microbiota of Wild-Type Mice.

Rohwer N, El Hage R, Smyl C, Ocvirk S, Goris T, Grune T, Swidsinski A, Weylandt KH · Nutrients · 2023-10-31

Preclinical / mechanistic

75. Analysis of strain, sex, and diet-dependent modulation of gut microbiota reveals candidate keystone organisms driving microbial diversity in response to American and ketogenic diets.

Salvador AC, Huda MN, Arends D, Elsaadi AM, Gacasan CA, Brockmann GA, Valdar W, Bennett BJ, Threadgill DW · Microbiome · 2023-10-03

Preclinical / mechanistic

76. Effect of the ketogenic diet on gut microbiome composition and metabolomics in polycystic ovarian syndrome rats induced by letrozole and a high-fat diet.

Wang R, Zhao Y, Fang X, Miao C, Ren N, Chen Y, Cheng W, Zhang Q · Nutrition (Burbank, Los Angeles County, Calif.) · 2023-06-08

Preclinical / mechanistic

77. Normal diet ameliorates obesity more safely and effectively than ketogenic diet does in high-fat diet-induced obesity mouse based on gut microbiota and lipid metabolism.

Dong Y, Song H, J Holmes A, Yan J, Ren C, Zhang Y, Zhao W, Yuan J, Cheng Y, Raubenheimer D, Cui Z · International journal of food sciences and nutrition · 2023-07-20

Clinical trial / intervention

78. Microbiota-gut-brain axis and ketogenic diet: how close are we to tackling epilepsy?

Mengoli M, Conti G, Fabbrini M, Candela M, Brigidi P, Turroni S, Barone M · Microbiome research reports · 2023-08-29

Preclinical / mechanistic

79. Ketogenic diet ameliorates attention deficit hyperactivity disorder in rats via regulating gut microbiota.

Liu Y, Yang C, Meng Y, Dang Y, Yang L · PloS one · 2023-08-16

Preclinical / mechanistic

80. Intermittent vs continuous ketogenic diet: Impact on seizures, gut microbiota, and mitochondrial metabolism.

Shearer J, Scantlebury MH, Rho JM, Tompkins TA, Mu C · Epilepsia · 2023-06-29

Preclinical / mechanistic

81. Ketogenic diet ameliorates autism spectrum disorders-like behaviors via reduced inflammatory factors and microbiota remodeling in BTBR T+ Itpr3tf/J mice.

Olivito I, Avolio E, Minervini D, Soda T, Rocca C, Angelone T, Iaquinta FS, Bellizzi D, De Rango F, Bruno R, De Bartolo L, Alò R, Canonaco M, Facciolo RM · Experimental neurology · 2023-05-05

Preclinical / mechanistic

82. Neuroprotective effect of a medium-chain triglyceride ketogenic diet on MPTP-induced Parkinson's disease mice: a combination of transcriptomics and metabolomics in the substantia nigra and fecal microbiome.

Zhang W, Chen S, Huang X, Tong H, Niu H, Lu L · Cell death discovery · 2023-07-17

Preclinical / mechanistic

83. Ketogenic Diet Alleviates Hypoglycemia-Induced Neuroinflammation via Modulation the Gut Microbiota in Mice.

Li C, Pan J, Sun P, Wang S, Wang S, Feng W, Chen S, Chai X, Zhao S, Zhu X · Molecular nutrition & food research · 2023-04-25

Preclinical / mechanistic

84. Ketogenic diet restrains herpes simplex encephalitis via gut microbes.

Shan T, Huang Y, Zhao Z, Li F, Wang Y, Ye C, Zheng K, Ren Z · Microbes and infection · 2022-10-18

Other

85. Dynamics of Gut Microbiota and Clinical Variables after Ketogenic and Mediterranean Diets in Drug-Naïve Patients with Type 2 Diabetes Mellitus and Obesity.

Deledda A, Palmas V, Heidrich V, Fosci M, Lombardo M, Cambarau G, Lai A, Melis M, Loi E, Loviselli A, Manzin A, Velluzzi F · Metabolites · 2022-11-10

Clinical trial / intervention

86. Effect of 30 days of ketogenic Mediterranean diet with phytoextracts on athletes' gut microbiome composition.

Mancin L, Amatori S, Caprio M, Sattin E, Bertoldi L, Cenci L, Sisti D, Bianco A, Paoli A · Frontiers in nutrition · 2022-10-25

Review

87. The Therapeutic Role of Short-Chain Fatty Acids Mediated Very Low-Calorie Ketogenic Diet-Gut Microbiota Relationships in Paediatric Inflammatory Bowel Diseases.

Alsharairi NA · Nutrients · 2022-10-03

Review

88. The gut microbiome as possible mediator of the beneficial effects of very low calorie ketogenic diet on type 2 diabetes and obesity: a narrative review.

Defeudis G, Rossini M, Khazrai YM, Pipicelli AMV, Brucoli G, Veneziano M, Strollo F, AMD-SID-SIEDP-Lifestyle Study Group Lazio, Bellia A, Bitterman O, Lauro D, Mora D, Santarelli E · Eating and weight disorders : EWD · 2022-07-01

Other

89. Ketogenic diets in healthy dogs induce gut and serum metabolome changes suggestive of anti-tumourigenic effects: A model for human ketotherapy trials.

Allenspach K, Borcherding DC, Iennarella-Servantez CA, Mosichuk AP, Atherly T, Sahoo DK, Kathrani A, Suchodolski JS, Bourgois-Mochel A, Serao MR, Serao NV, Willette A, Perez BA, Gabriel V, Mao S, Kilburn L, Dang V, Borts D, Almada LL, Fernandez-Zapico ME, Phillips GJ, Jergens AE, Mochel JP · Clinical and translational medicine · 2022-08-15

Clinical trial / intervention

90. Ketogenic Diet: A Dietary Intervention via Gut Microbiome Modulation for the Treatment of Neurological and Nutritional Disorders (a Narrative Review).

Lim JM, Letchumanan V, Tan LT, Hong KW, Wong SH, Ab Mutalib NS, Lee LH, Law JW · Nutrients · 2022-08-30

Clinical trial / intervention

91. Ketogenic and Low FODMAP Diet in Therapeutic Management of a Young Autistic Patient with Epilepsy and Dysmetabolism Poorly Responsive to Therapies: Clinical Response and Effects of Intestinal Microbiota.

Bertuccioli A, Cardinali M, Di Pierro F, Zonzini GB, Matera MR · International journal of molecular sciences · 2022-08-08

Other

92. The gut microbiome and the ketogenic diet: A pathway towards treatment optimization in infantile spasms.

McCafferty C · EBioMedicine · 2022-03-23

Randomized clinical trial

93. Ketogenic Effects of Multiple Doses of a Medium Chain Triglycerides Enriched Ketogenic Formula in Healthy Men under the Ketogenic Diet: A Randomized, Double-Blinded, Placebo-Controlled Study.

Nakamura K, Hagihara K, Nagai N, Egashira R, Takeuchi M, Nakano M, Saito H, Moriguchi M, Tonari S, Watanabe S, Miyake A, Ashida K · Nutrients · 2022-03-12

Review

94. Molecular Mechanisms Underlying the Bioactive Properties of a Ketogenic Diet.

Murakami M, Tognini P · Nutrients · 2022-02-13

Systematic review / meta-analysis

95. The ketogenic diet: its impact on human gut microbiota and potential consequent health outcomes: a systematic literature review.

Rew L, Harris MD, Goldie J · Gastroenterology and hepatology from bed to bench · 2022-04-28

Other

96. Effects of dietary components on intestinal short-chain fatty acids (SCFAs) synthesis in healthy adult persons following a ketogenic diet.

Gudan A, Skonieczna-Żydecka K, Palma J, Drozd A, Stachowska E · Roczniki Panstwowego Zakladu Higieny · 2022-03-24

Systematic review / meta-analysis

97. The Role of the Gut Microbiota on the Beneficial Effects of Ketogenic Diets.

Attaye I, van Oppenraaij S, Warmbrunn MV, Nieuwdorp M · Nutrients · 2021-12-31

Other

98. Corrigendum: The Potential Roles of Very Low Calorie, Very Low Calorie Ketogenic Diets and Very Low Carbohydrate Diets on the Gut Microbiota Composition.

Rondanelli M, Gasparri C, Peroni G, Faliva MA, Naso M, Perna S, Bazire P, Sajoux I, Maugeri R, Rigon C · Frontiers in endocrinology · 2021-12-22

Preclinical / mechanistic

99. The impact of Scn1a deficiency and ketogenic diet on the intestinal microbiome: A study in a genetic Dravet mouse model.

Miljanovic N, Potschka H · Epilepsy research · 2021-11-24

Review

100. Microbiota-gut-brain axis: A novel potential target of ketogenic diet for epilepsy.

Tang Y, Wang Q, Liu J · Current opinion in pharmacology · 2021-10-01

Review

101. The Role of Short-Chain Fatty Acids in Mediating Very Low-Calorie Ketogenic Diet-Infant Gut Microbiota Relationships and Its Therapeutic Potential in Obesity.

Alsharairi NA · Nutrients · 2021-10-21

Preclinical / mechanistic

102. Ketogenic diet aggravates colitis, impairs intestinal barrier and alters gut microbiota and metabolism in DSS-induced mice.

Li S, Zhuge A, Wang K, Lv L, Bian X, Yang L, Xia J, Jiang X, Wu W, Wang S, Wang Q, Li L · Food & function · 2021-10-19

Preclinical / mechanistic

103. Alterations in the gut microbiota contribute to cognitive impairment induced by the ketogenic diet and hypoxia.

Olson CA, Iñiguez AJ, Yang GE, Fang P, Pronovost GN, Jameson KG, Rendon TK, Paramo J, Barlow JT, Ismagilov RF, Hsiao EY · Cell host & microbe · 2021-08-05

Clinical trial / intervention

104. A Root in Synapsis and the Other One in the Gut Microbiome-Brain Axis: Are the Two Poles of Ketogenic Diet Enough to Challenge Glioblastoma?

Montella L, Sarno F, Altucci L, Cioffi V, Sigona L, Di Colandrea S, De Simone S, Marinelli A, Facchini BA, De Vita F, Berretta M, de Falco R, Facchini G · Frontiers in nutrition · 2021-07-22

Observational human study

105. Gut flora and metabolism are altered in epilepsy and partially restored after ketogenic diets.

Gong X, Cai Q, Liu X, An D, Zhou D, Luo R, Peng R, Hong Z · Microbial pathogenesis · 2021-04-21

Preclinical / mechanistic

106. Ketogenic diet alleviates colitis by reduction of colonic group 3 innate lymphoid cells through altering gut microbiome.

Kong C, Yan X, Liu Y, Huang L, Zhu Y, He J, Gao R, Kalady MF, Goel A, Qin H, Ma Y · Signal transduction and targeted therapy · 2021-04-23

Preclinical / mechanistic

107. Ketogenic Diets Induced Glucose Intolerance and Lipid Accumulation in Mice with Alterations in Gut Microbiota and Metabolites.

Li Y, Yang X, Zhang J, Jiang T, Zhang Z, Wang Z, Gong M, Zhao L, Zhang C · mBio · 2021-03-30

Preclinical / mechanistic

108. The Ketogenic Diet Reduces the Harmful Effects of Stress on Gut Mitochondrial Biogenesis in a Rat Model of Irritable Bowel Syndrome.

Chimienti G, Orlando A, Lezza AMS, D'Attoma B, Notarnicola M, Gigante I, Pesce V, Russo F · International journal of molecular sciences · 2021-03-28

Preclinical / mechanistic

109. A review on preventive role of ketogenic diet (KD) in CNS disorders from the gut microbiota perspective.

Rawat K, Singh N, Kumari P, Saha L · Reviews in the neurosciences · 2020-10-19

Preclinical / mechanistic

110. Gut microbiota modulation by both Lactobacillus fermentum MSK 408 and ketogenic diet in a murine model of pentylenetetrazole-induced acute seizure.

Eor JY, Tan PL, Son YJ, Kwak MJ, Kim SH · Epilepsy research · 2020-11-21

Review

111. The Role of Short-Chain Fatty Acids in the Interplay between a Very Low-Calorie Ketogenic Diet and the Infant Gut Microbiota and Its Therapeutic Implications for Reducing Asthma.

Alsharairi NA · International journal of molecular sciences · 2020-12-16

Review

112. Ketogenic diet and Neuroinflammation.

Koh S, Dupuis N, Auvin S · Epilepsy research · 2020-09-06

Review

113. A gut feeling about the ketogenic diet in epilepsy.

Pittman QJ · Epilepsy research · 2020-06-29

Preclinical / mechanistic

114. Ketone production by ketogenic diet and by intermittent fasting has different effects on the gut microbiota and disease progression in an Alzheimer's disease rat model.

Park S, Zhang T, Wu X, Yi Qiu J · Journal of clinical biochemistry and nutrition · 2020-03-20

Review

115. Exploring the mechanisms of action of the antidepressant effect of the ketogenic diet.

Ricci A, Idzikowski MA, Soares CN, Brietzke E · Reviews in the neurosciences · 2019-08-08

Clinical trial / intervention

116. Ketogenic Diets Alter the Gut Microbiome Resulting in Decreased Intestinal Th17 Cells.

Ang QY, Alexander M, Newman JC, Tian Y, Cai J, Upadhyay V, Turnbaugh JA, Verdin E, Hall KD, Leibel RL, Ravussin E, Rosenbaum M, Patterson AD, Turnbaugh PJ · Cell · 2020-05-20

Other

117. Ketone Bodies Exert Ester-Ordinary Suppression of Bifidobacteria and Th17 Cells.

Olson CA, Lum GR, Hsiao EY · Cell metabolism · 2020-06-04

Randomized clinical trial

118. Effect of Synbiotic Supplementation in a Very-Low-Calorie Ketogenic Diet on Weight Loss Achievement and Gut Microbiota: A Randomized Controlled Pilot Study.

Gutiérrez-Repiso C, Hernández-García C, García-Almeida JM, Bellido D, Martín-Núñez GM, Sánchez-Alcoholado L, Alcaide-Torres J, Sajoux I, Tinahones FJ, Moreno-Indias I · Molecular nutrition & food research · 2019-08-29

Review

119. Ketogenic Diet and Microbiota: Friends or Enemies?

Paoli A, Mancin L, Bianco A, Thomas E, Mota JF, Piccini F · Genes · 2019-07-15

Review

120. Crosstalk between the Ketogenic Diet and Epilepsy: From the Perspective of Gut Microbiota.

Fan Y, Wang H, Liu X, Zhang J, Liu G · Mediators of inflammation · 2019-06-03

Clinical trial / intervention

121. The Impact of Low-FODMAPs, Gluten-Free, and Ketogenic Diets on Gut Microbiota Modulation in Pathological Conditions.

Reddel S, Putignani L, Del Chierico F · Nutrients · 2019-02-12

Clinical trial / intervention

122. The ketogenic diet influences taxonomic and functional composition of the gut microbiota in children with severe epilepsy.

Lindefeldt M, Eng A, Darban H, Bjerkner A, Zetterström CK, Allander T, Andersson B, Borenstein E, Dahlin M, Prast-Nielsen S · NPJ biofilms and microbiomes · 2019-01-23

Other

123. Gut Microbes May Account for the Anti-Seizure Effects of the Ketogenic Diet.

Hampton T · JAMA · 2018-10-05

Other

124. Gut Microbiota, the Ketogenic Diet and Epilepsy.

Spinelli E, Blackford R · Pediatric neurology briefs · 2018-09-21

Other

125. The Gut Microbiota Mediates the Anti-Seizure Effects of the Ketogenic Diet.

Olson CA, Vuong HE, Yano JM, Liang QY, Nusbaum DJ, Hsiao EY · Cell · 2018-07-16

Clinical trial / intervention

126. Ketogenic diet enhances neurovascular function with altered gut microbiome in young healthy mice.

Ma D, Wang AC, Parikh I, Green SJ, Hoffman JD, Chlipala G, Murphy MP, Sokola BS, Bauer B, Hartz AMS, Lin AL · Scientific reports · 2018-04-27

Other

127. Reduced Mass and Diversity of the Colonic Microbiome in Patients with Multiple Sclerosis and Their Improvement with Ketogenic Diet.

Swidsinski A, Dörffel Y, Loening-Baucke V, Gille C, Göktas Ö, Reißhauer A, Neuhaus J, Weylandt KH, Guschin A, Bock M · Frontiers in microbiology · 2017-06-28

Preclinical / mechanistic

128. Short-term impact of a classical ketogenic diet on gut microbiota in GLUT1 Deficiency Syndrome: A 3-month prospective observational study.

Tagliabue A, Ferraris C, Uggeri F, Trentani C, Bertoli S, de Giorgis V, Veggiotti P, Elli M · Clinical nutrition ESPEN · 2016-12-18

Preclinical / mechanistic

129. Ketogenic diet modifies the gut microbiota in a murine model of autism spectrum disorder.

Newell C, Bomhof MR, Reimer RA, Hittel DS, Rho JM, Shearer J · Molecular autism · 2016-09-01

Randomized clinical trial

130. Taxonomic and functional shifts in the microbiome of severely obese, prediabetic patients: Ketogenic diet versus energy-matched standard diet.

Stone J, Tripyla A, Scalise MC, Balmer ML, Bally L, Meinel DM · Diabetes, obesity & metabolism · 2025-12-15

Clinical trial / intervention

131. The anti-epileptic mechanism of a ketogenic diet regulating the gut microbiota via SIRT2 activation of the PI3K/AKT signaling pathway.

Li M, Deng H, Ma L, Sun M · Neuroscience letters · 2025-12-09

Other

132. The ketogenic diet alters microbiome-metabolome profiles to improve West syndrome therapy.

Xie G, Zhou Q, Liao J, Zheng Y, Wang W, Shen K · Pediatric investigation · 2025-11-19

Review

133. Exploring the Ketogenic Diet as Adjunctive Therapy in Multiple Sclerosis: A Review.

Rasheed S, Uzair M, Anas M, Batool Naqvi SS, Aijaz U, Raza AA, Samadi A · Restorative neurology and neuroscience · 2025-12-10

Other

134. Gut microbiota regulates hepatic ketogenesis and lipid accumulation in ketogenic diet-induced hyperketonemia by disrupting bile acid metabolism.

Luo Z, Huang Y, Yong K, Wu D, Zheng L, Yao X, Shen L, Yu S, Wang B, Cao S · Gut microbes · 2025-04-23

Preclinical / mechanistic

135. Ketogenic diet inhibits glioma progression by promoting gut microbiota-derived butyrate production.

Chen ML, He Y, Dong XH, Liu HF, Yan ZX, Lu XL, Miao QQ, Zhao QN, Zhang H, Luo L, Wang S, Li JY, Xiang DF, Lin Y, Li TR, Zhou XY, Zhou YY, Mao M, Zhang X, Wei H, Shi Y, Liu XD, Ping YF, Bian XW · Cancer cell · 2025-09-25

Clinical trial / intervention

136. Mechanisms of a Ketogenic Diet and High-Carbohydrate Diets on Cognitive Impairment and the Microbiota-Gut-Brain Axis.

Shang W, Gu Z, Li L, Cheng L, Hong Y · Nutrition reviews · 2025-10-30

Preclinical / mechanistic

137. A novel ketogenic diet that reduces seizures and prevents liver steatosis leads to related gut microbiome changes and restores cecal short-chain fatty acid levels in the rapid kindling rat model of epileptogenesis.

Meeusen H, Lohr J, van Eijndthoven T, Kalf RS, Roeselers G, van Helvoort A, Gorter JA, van Vliet EA, Tims S, Silva JP, Aronica E · Gut microbes reports · 2025-10-09

Preclinical / mechanistic

138. Ketogenic Diet Modulates Gut Microbiota-Brain Metabolite Axis in a Sex- and Genotype-Specific Manner in APOE4 Mice.

Ivanich K, Yackzan A, Flemister A, Chang YH, Xing X, Chen A, Yanckello LM, Sun M, Aware C, Govindarajan M, Kramer S, Ericsson A, Lin AL · Journal of neurochemistry · 2025-07-18

Clinical trial / intervention

139. The Interplay between the Gut and Ketogenic Diets in Health and Disease.

Mu C, Rho JM, Shearer J · Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025-08-23

Clinical trial / intervention

140. Fecal Metaproteomics as a Tool to Monitor Functional Modifications Induced in the Gut Microbiota by Ketogenic Diet: A Case Study.

Tanca A, Masia S, Giustacchini P, Uzzau S · Proteomics · 2025-01-05

Clinical trial / intervention

141. Nutritional Interventions in Amyotrophic Lateral Sclerosis: From Ketogenic Diet and Neuroprotective Nutrients to the Microbiota-Gut-Brain Axis Regulation.

Nabakhteh S, Lotfi A, Afsartaha A, Khodadadi ES, Abdolghaderi S, Mohammadpour M, Shokri Y, Kiani P, Ehtiati S, Khakshournia S, Khatami SH · Molecular neurobiology · 2025-03-17

Preclinical / mechanistic

142. Author Correction: Dietary fiber content in clinical ketogenic diets modifies the gut microbiome and seizure resistance in mice.

Özcan E, Yu KB, Dinh L, Lum GR, Lau K, Hsu J, Arino M, Paramo J, Lopez-Romero A, Hsiao EY · Nature communications · 2025-06-02

Clinical trial / intervention

143. Ketogenic diet suppresses colorectal cancer through the gut microbiome long chain fatty acid stearate.

Tsenkova M, Brauer M, Pozdeev VI, Kasakin M, Busi SB, Schmoetten M, Cheung D, Meyers M, Rodriguez F, Gaigneaux A, Koncina E, Gilson C, Schlicker L, Herebian D, Schmitz M, de Nies L, Mayatepek E, Haan S, de Beaufort C, Cramer T, Meiser J, Linster CL, Wilmes P, Letellier E · Nature communications · 2025-02-20

Observational human study

144. Characterizing the fecal microbiome in patients on the ketogenic diet for drug resistant epilepsy.

Freibauer A, Pai N, RamachandranNair R · Heliyon · 2025-01-02

Clinical trial / intervention

145. Impact of Ketogenic and Mediterranean Diets on Gut Microbiota Profile and Clinical Outcomes in Drug-Naïve Patients with Diabesity: A 12-Month Pilot Study.

Palmas V, Deledda A, Heidrich V, Sanna G, Cambarau G, Fosci M, Puglia L, Cappai EA, Lai A, Loviselli A, Manzin A, Velluzzi F · Metabolites · 2025-01-06

Candida & Mycobiome Recent peer-reviewed literature

Source-audited selection from the connected PDF archive. Systematic reviews/meta-analyses and recent human evidence are prioritized when available; sparse areas are explicitly kept sparse.

Direct but low-level evidence

1. Consuming an All-Meat Ketogenic Diet for the Long-Term Management of Candida

Original publication title: Consuming an All-Meat Ketogenic Diet for the Long-Term Management of Candida

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Preclinical / mechanistic

2. Ketogenic β-hydroxybutyrate-regulated β-hydroxybutyrylation of HSPE1 alleviates neuronal apoptosis in MPTP/MPP+ induced Parkinson's disease models.

Liu Y, Wang M, Shi S, Zhang J, Wang W, Xiang J · Food & function · 2026-08-03

Observational human study

3. Cognitive behavioral therapy for bipolar disorder: patient-level participation barriers and ketogenic metabolic therapy as a candidate adjunct.

Laurent N · Frontiers in psychology · 2026-06-15

Clinical trial / intervention

4. Ketogenic metabolic therapy as a candidate adjunct for CBTp delivery in schizophrenia spectrum disorders.

Laurent N · Frontiers in psychology · 2026-03-25

Clinical trial / intervention

5. DNA methylation of antiseizure medication metabolism genes and pharmacokinetic changes in adult epilepsy patients treated with the modified Atkins diet.

Gervin K, Kverneland M, Nakken KO, Rudi K, Iversen PO, Landmark CJ, Selmer KK · Genes & nutrition · 2026-03-13

Clinical trial / intervention

6. A ketogenic diet enhances fluconazole efficacy in murine models of systemic fungal infection.

Palmucci JR, Sells BE, Giamberardino CD, Toffaletti DL, Dai B, Asfaw YG, Dubois LG, Li Z, Theriot B, Schell WA, Hope W, Tenor JL, Perfect JR · mBio · 2024-04-15

Preclinical / mechanistic

7. Analysis of strain, sex, and diet-dependent modulation of gut microbiota reveals candidate keystone organisms driving microbial diversity in response to American and ketogenic diets.

Salvador AC, Huda MN, Arends D, Elsaadi AM, Gacasan CA, Brockmann GA, Valdar W, Bennett BJ, Threadgill DW · Microbiome · 2023-10-03

Clinical trial / intervention

8. Consuming an All-Meat Ketogenic Diet for the Long-Term Management of Candida Vulvovaginitis and Vaginal Hidradenitis Suppurativa: A 47-Month Follow-Up Case Report.

Yar N, Mukona LT, Nguyen K, Nalbandyan L, Mukona L, St Fleur G, Lamberty NL, Zullo K, Le A, Van A, Allen B · Cureus · 2022-10-20

Other

9. Metabolic effects, safety, and acceptability of very low-calorie ketogenic dietetic scheme on candidates for bariatric surgery.

Pilone V, Tramontano S, Renzulli M, Romano M, Cobellis L, Berselli T, Schiavo L · Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery · 2018-03-21

Ketogenic Metabolic Therapies

Exogenous Ketones Recent peer-reviewed literature

Expanded source-audited selection from the connected PDF archive. Recent reviews and human studies are placed before older or more mechanistic work.

Recent review · 2025

1. The science of ketogenic supplements for athletes

Original publication title: The science of ketogenic supplements for athletes

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Review

2. Exogenous Ketone Supplementation and Ketogenic Diets for Exercise: Considering the Effect on Skeletal Muscle Metabolism

Original publication title: Exogenous Ketone Supplementation and Ketogenic Diets for Exercise: Considering the Effect on Skeletal Muscle Metabolism

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Review

3. Ketogenic diets and ketone supplementation: a strategy for therapeutic intervention

Original publication title: Ketogenic diets and ketone supplementation: a strategy for therapeutic intervention

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Review / translational

4. Exogenous Ketones and Lactate as a Potential Therapeutic Intervention for Brain Injury and Neurodegenerative Conditions

Original publication title: Exogenous Ketones and Lactate as a Potential Therapeutic Intervention for Brain Injury and Neurodegenerative Conditions

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Human study

5. Impact of ketogenic diet and ketone diester supplementation on body composition and performance

Original publication title: Impact of ketogenic diet and ketone diester supplementation on body composition and performance

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Review

6. Ketones for Post-exercise Recovery: Potential Applications and Mechanisms

Original publication title: Ketones for Post-exercise Recovery: Potential Applications and Mechanisms

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Mini-review

7. Efficacy and Safety of Ketone Supplementation or Ketogenic Diets for Alzheimer's Disease: A Mini Review

Original publication title: Efficacy and Safety of Ketone Supplementation or Ketogenic Diets for Alzheimer's Disease: A Mini Review

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Review

8. Exogenous ketone supplements in athletic contexts

Original publication title: Exogenous ketone supplements in athletic contexts

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Preclinical / mechanistic

9. Ketone ester alleviates sepsis-associated liver injury through β-hydroxybutyrylation of STAT1.

Bai Y, Li K, Zhu D, Li R, Yan Y, Zhong C, Zha L, Wang Q · Immunobiology · 2026-09-11

Other

10. Integrated UPLC-MS/MS with interpretable artificial intelligence-enhanced Raman and near-infrared spectroscopy for multi-objective monitoring of ginkgo ketone ester tablets column purification.

Zhou Q, Jiang M, Wang D, Wang J, Tao Y · Journal of pharmaceutical and biomedical analysis · 2026-07-17

Clinical trial / intervention

11. Halting cyst progression in ADPKD using long-term ketogenic metabolic therapy and supplementation with exogenous ketones and alkaline citrate-a case series.

Messing M, Muensterman E, Marcon S, Weimbs T · Frontiers in nutrition · 2026-06-29

Randomized clinical trial

12. Exogenous Ketones Preserve Rate of Force Development in Young Adults.

Stoner JT, Buga A, Crabtree CD, Robinson BT, Decker DD, Sapper TN, Kackley ML, Kraemer WJ, Volek JS · Journal of strength and conditioning research · 2026-06-15

Preclinical / mechanistic

13. Semaglutide-induced loss of skeletal muscle mass is blunted by co-administration of ketone esters.

Abuetabh Y, Schmidt MA, Naganuma M, Vaka R, El-Ghiaty MA, Braun S, Kwan EA, Zolondek MC, Sahid D, Khan L, Shandal RK, Trudeau AL, Li Y, Malik SO, Sun Q, Roth DK, Morales-Llamas DY, Levasseur JL, Ferdaoussi M, Fahlman RP, Dyck JR · JCI insight · 2026-06-09

Preclinical / mechanistic

14. Diet-Dependent Cognitive Benefits of Exogenous Ketone Body Precursor, (R,S)-1,3,-Butanediol, in a Mouse Model of Tauopathy.

Fulghum K, Hayir A, Ankeriasniemi R, Shaddy-Gouvion C, Vang CM, Salathe SF, Queathem ED, Hughey CC, Haeri M, Thyfault JP, Puchalska P, Crawford PA · bioRxiv : the preprint server for biology · 2026-06-08

Preclinical / mechanistic

15. Ketone Ester Attenuates Thoracic Aortic Aneurysm and Dissection by Suppressing Ferroptosis.

Shrestha S, Wu Y, Li J, Du X, Song P · Cells · 2026-05-01

Clinical trial / intervention

16. Metabolic and gut microbiota effects of ketogenic diet and exogenous ketone salts in a rat model of metabolic syndrome.

Pereira-Rodrigues A, Gonçalves A, Alves IN, Mendes CS, Silva C, Campos J, Sampaio-Maia B, Falcão-Pires I, Araujo R · European journal of nutrition · 2026-04-28

Clinical trial / intervention

17. Ketone ester supplementation in aged mice reduces activation of B cell subsets.

Adkisson-Floro A, Tiwari R, Nomura M, Riley RR, Kwok R, Sellegounder D, Khalid MM, Kasler HG, Newman JC, Verdin E · bioRxiv : the preprint server for biology · 2026-04-22

Systematic review / meta-analysis

18. The effect of exogenous ketone bodies on cognition across health and disease: a systematic review and meta-analysis.

Bonnechère B, Stephens EB, Boileau AC, Ducker M, Stubbs BJ · Frontiers in nutrition · 2026-04-15

Other

19. From Fuel to Flow: Translating the Beneficial Hemodynamic Effects of Exogenous Ketones in the ICU.

Elliott DM, Katz JN, Selvaraj S · JACC. Heart failure · 2026-04-03

Other

20. Hemodynamic Effects of Oral Ketone Ester in Acutely Decompensated Heart Failure With Low Cardiac Output Syndrome.

Sramko M, Wohlfahrt P, Kissimon F, Svirlochova V, Franekova J, Kautzner J, Melenovsky V · JACC. Heart failure · 2026-01-07

Other

21. Metabolic and Pharmacokinetic Profiling of a Ketone Ester by Background SGLT2 Inhibitor Therapy in HFrEF.

Selvaraj S, Kwee LC, Thompson EJ, He M, Hornik CP, Devore AD, Patel CB, Mentz RJ, Fudim M, Taylor L, Milosovic S, Hurdle M, Cade WT, Ilkayeva O, Muehlbauer MJ, Newgard CB, Kelly DP, Zamani P, Margulies KB, Shah SH · JACC. Basic to translational science · 2024-11-15

Other

22. Neurohormonal and Renal Effects of 14-Day Oral Ketone Ester Treatment in Patients With Heart Failure With Reduced Ejection Fraction.

Berg-Hansen K, Gopalasingam N, Christensen KH, Svart M, Rittig N, Nielsen R, Lodberg K, Møller N, Wiggers H · Circulation. Heart failure · 2024-12-24

Clinical trial / intervention

23. Exogenous ketone bodies and the ketogenic diet as a treatment option for neurodevelopmental disorders.

Omori NE, Malys MK, Woo G, Mansor L · Frontiers in nutrition · 2024-12-19

Preclinical / mechanistic

24. Exogenous ketone therapy does not protect brain tissue after moderate-sized intracerebral hemorrhage despite signs of early neurological benefit.

Sander NH, Soni S, Wilkinson CM, Khiabani E, Dyck JRB, Colbourne F · PloS one · 2024-12-05

Clinical trial / intervention

25. Ketone ester-enriched diet ameliorates motor and dopamine release deficits in MitoPark mice.

Mahajan VR, Nadel JA, King MT, Pawlosky RJ, Davis MI, Veech RL, Lovinger DM, Salinas AG · The European journal of neuroscience · 2024-11-11

Randomized clinical trial

26. Randomized Crossover Trial of 2-Week Ketone Ester Treatment in Patients With Type 2 Diabetes and Heart Failure With Preserved Ejection Fraction.

Gopalasingam N, Berg-Hansen K, Christensen KH, Ladefoged BT, Poulsen SH, Andersen MJ, Borlaug BA, Nielsen R, Møller N, Wiggers H · Circulation · 2024-08-20

Preclinical / mechanistic

27. Ketone Esters Partially and Selectively Rescue Mitochondrial Bioenergetics After Acute Cervical Spinal Cord Injury in Rats: A Time-Course.

Seira O, Park HD, Liu J, Poovathukaran M, Clarke K, Boushel R, Tetzlaff W · Cells · 2024-10-22

Randomized clinical trial

28. An Exogenous Ketone Ester Slows Tumor Progression in Murine Breast and Renal Cancer Models.

Ogbonna HN, Roberts Z, Godwin N, Muri P, Turbitt WJ, Swalley ZN, Dempsey FR, Stephens HR, Zhang J, Plaisance EP, Norian LA · Cancers · 2024-10-04

Randomized clinical trial

29. Exploratory functional and quality of life outcomes with daily consumption of the ketone ester bis-octanoyl (R)-1,3-butanediol in healthy older adults: a randomized, parallel arm, double-blind, placebo-controlled study.

Stubbs BJ, Stephens EB, Senadheera C, Diaz SR, Peralta S, Alexander L, Silverman-Martin W, Kurtzig J, Fernando BA, Yurkovich JT, Garcia TY, Yukawa M, Morris J, Johnson JB, Newman JC · medRxiv : the preprint server for health sciences · 2024-09-18

Randomized clinical trial

30. Rationale and protocol for a safety, tolerability and feasibility randomized, parallel arm, double-blind, placebo-controlled, pilot study of a novel ketone ester targeting frailty via immunometabolic geroscience mechanisms.

Stubbs BJ, Alvarez Azañedo G, Peralta S, Diaz SR, Gray W, Alexander L, Silverman-Martin W, Garcia TY, Blonquist TM, Upadhyay V, Turnbaugh PJ, Johnson JB, Newman JC · PloS one · 2024-09-18

Review

31. Exogenous ketone esters as a potential therapeutic for treatment of sarcopenic obesity.

Deemer SE, Roberts BM, Smith DL, Plaisance EP, Philp A · American journal of physiology. Cell physiology · 2024-05-20

Randomized clinical trial

32. Effect of Acute Nutritional Ketosis on Circulating Levels of Growth Differentiation Factor 15: Findings from a Cross-Over Randomised Controlled Trial.

Charles S, Liu Y, Bharmal SH, Kimita W, Petrov MS · Biomolecules · 2024-06-06

Randomized clinical trial

33. Daily consumption of ketone ester, bis-octanoyl (R)-1,3-butanediol, is safe and tolerable in healthy older adults, a randomized, parallel arm, double-blind, placebo-controlled, pilot study.

Stubbs BJ, Stephens EB, Senadheera C, Peralta S, Roa-Diaz S, Alexander L, Silverman-Martin W, Garcia TY, Yukawa M, Morris J, Blonquist TM, Johnson JB, Newman JC · medRxiv : the preprint server for health sciences · 2024-05-05

Randomized clinical trial

34. A randomized open-label, observational study of the novel ketone ester, bis octanoyl (R)-1,3-butanediol, and its acute effect on ß-hydroxybutyrate and glucose concentrations in healthy older adults.

Stephens EB, Senadheera C, Roa-Diaz S, Peralta S, Alexander L, Silverman-Martin W, Yukawa M, Morris J, Johnson JB, Newman JC, Stubbs BJ · medRxiv : the preprint server for health sciences · 2024-04-18

Randomized clinical trial

35. Tolerability and Acceptability of an Exogenous Ketone Monoester and Ketone Monoester/Salt Formulation in Humans.

Bolyard ML, Graziano CM, Fontaine KR, Sayer RD, Fisher G, Plaisance EP · Nutrients · 2023-11-22

Randomized clinical trial

36. Rationale and protocol for a safety, tolerability and feasibility randomized, parallel group, double-blind, placebo-controlled, pilot study of a novel ketone ester targeting frailty via immunometabolic geroscience mechanisms.

Stubbs BJ, Alvarez-Azanedo G, Peralta S, Roa-Diaz S, Gray W, Alexander L, Silverman-Martin W, Garcia T, Blonquist TM, Upadhyay V, Turnbaugh PJ, Johnson JB, Newman JC · medRxiv : the preprint server for health sciences · 2023-10-26

Review

37. Effects of ketone bodies on energy expenditure, substrate utilization, and energy intake in humans.

Fernández-Verdejo R, Mey JT, Ravussin E · Journal of lipid research · 2023-09-11

Randomized clinical trial

38. Beneficial Effects of Ketone Ester in Patients With Cardiogenic Shock: A Randomized, Controlled, Double-Blind Trial.

Berg-Hansen K, Christensen KH, Gopalasingam N, Nielsen R, Eiskjær H, Møller N, Birkelund T, Christensen S, Wiggers H · JACC. Heart failure · 2023-07-12

Other

39. Quantitative Determination of (R)-3-Hydroxybutyl (R)-3-Hydroxybutyrate (Ketone Ester) and Its Metabolites Beta-hydroxybutyrate, 1-3-Butanediol, and Acetoacetate in Human Plasma Using LC-MS.

Panse N, Halquist M, Gerk PM · AAPS PharmSciTech · 2023-09-12

Preclinical / mechanistic

40. Ketone ester administration improves glycemia in obese mice.

Tabatabaei Dakhili SA, Yang K, Locatelli CAA, Saed CT, Greenwell AA, Chan JSF, Chahade JJ, Scharff J, Al-Imarah S, Eaton F, Crawford PA, Gopal K, Mulvihill EE, Ussher JR · American journal of physiology. Cell physiology · 2023-08-14

Randomized clinical trial

41. A Novel Powder Formulation of the Ketone Ester, Bis Hexanoyl (R)-1,3-Butanediol, Rapidly Increases Circulating ß-Hydroxybutyrate Concentrations in Healthy Adults.

Nieman KM, Anthony JC, Stubbs BJ · Journal of the American Nutrition Association · 2022-10-24

Systematic review / meta-analysis

42. A systematic review and meta-regression of exogenous ketone infusion rates and resulting ketosis-A tool for clinicians and researchers.

Storoschuk KL, Wood TR, Stubbs BJ · Frontiers in physiology · 2023-06-28

Randomized clinical trial

43. Impact of one-day fasting, ketogenic diet or exogenous ketones on control of energy balance in healthy participants.

Hägele FA, Dörner R, Koop J, Lübken M, Seidel U, Rimbach G, Müller MJ, Bosy-Westphal A · Clinical nutrition ESPEN · 2023-04-10

Other

44. Ketone Esters and Their Effects on Carbohydrate Metabolism During Exercise.

Gonzalez JT · The Journal of nutrition · 2023-04-11

Randomized clinical trial

45. Oral ketone esters acutely improve myocardial contractility in post-hospitalized COVID-19 patients: A randomized placebo-controlled double-blind crossover study.

Wodschow HZ, Davidovski FS, Christensen J, Lassen MCH, Skaarup KG, Nygaard H, Møller N, Rungby J, Biering-Sørensen T, Rossing P, Jensen NJ, Laursen JC · Frontiers in nutrition · 2023-02-09

Preclinical / mechanistic

46. Effects of an exogenous ketone ester using multi-omics in skeletal muscle of aging C57BL/6J male mice.

Roberts BM, Deemer SE, Smith DL, Mobley JA, Musi N, Plaisance EP · Frontiers in nutrition · 2022-11-15

Preclinical / mechanistic

47. Exogenous ketone ester administration attenuates systemic inflammation and reduces organ damage in a lipopolysaccharide model of sepsis.

Soni S, Martens MD, Takahara S, Silver HL, Maayah ZH, Ussher JR, Ferdaoussi M, Dyck JRB · Biochimica et biophysica acta. Molecular basis of disease · 2022-07-25

Other

48. [Ginkgo biloba Ketone Ester Tablets with different release rates prepared by fused deposition modeling 3D printing technology].

Li YY, Chen C, Wang HX, Xiang BB, Li Z · Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica · 2022-09-27

Clinical trial / intervention

49. Observation on the Efficacy of Ginkgo Ketone Ester Drop Pill in Improving Hypertension Combined with Carotid Atherosclerotic Plaque.

Zhang J, Ma Y · Emergency medicine international · 2022-06-30

Clinical trial / intervention

50. Efficacy and safety of ketone ester infusion to prevent muscle weakness in a mouse model of sepsis-induced critical illness.

Weckx R, Goossens C, Derde S, Pauwels L, Vander Perre S, Van den Berghe G, Langouche L · Scientific reports · 2022-06-22

Preclinical / mechanistic

51. The ketone ester, 3-hydroxybutyl-3-hydroxybutyrate, attenuates neurobehavioral deficits and improves neuropathology following controlled cortical impact in male rats.

Almeida-Suhett C, Namboodiri AM, Clarke K, Deuster PA · Nutritional neuroscience · 2020-12-09

Randomized clinical trial

52. Comparison of Exogenous Ketone Administration Versus Dietary Carbohydrate Restriction on Myocardial Glucose Suppression: A Crossover Clinical Trial.

Selvaraj S, Margulies KB, Dugyala S, Schubert E, Tierney A, Arany Z, Pryma DA, Shah SH, Rame JE, Kelly DP, Bravo PE · Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2021-10-21

Randomized clinical trial

53. The Effects of 10-Day Exogenous Ketone Consumption on Repeated Time Trial Running Performances: A Randomized-Control Trial.

Jo E, Silva Ms SC, Auslander PhD AT, Arreglado Ms JP, Elam PhD ML, Osmond Ms AD, Steinberg Ms R, Wong Ms MWH · Journal of dietary supplements · 2020-10-28

Randomized clinical trial

54. Nutritional Formulation for Patients with Angelman Syndrome: A Randomized, Double-Blind, Placebo-Controlled Study of Exogenous Ketones.

Carson RP, Herber DL, Pan Z, Phibbs F, Key AP, Gouelle A, Ergish P, Armour EA, Patel S, Duis J · The Journal of nutrition · 2021-04-08

Preclinical / mechanistic

55. Ketone Ester D-β-Hydroxybutyrate-(R)-1,3 Butanediol Prevents Decline in Cardiac Function in Type 2 Diabetic Mice.

Thai PN, Miller CV, King MT, Schaefer S, Veech RL, Chiamvimonvat N, Bers DM, Dedkova EN · Journal of the American Heart Association · 2021-09-29

Preclinical / mechanistic

56. Exogenous ketone ester delays CNS oxygen toxicity without impairing cognitive and motor performance in male Sprague-Dawley rats.

Stavitzski NM, Landon CS, Hinojo CM, Poff AM, Rogers CQ, D'Agostino DP, Dean JB · American journal of physiology. Regulatory, integrative and comparative physiology · 2021-06-16

Preclinical / mechanistic

57. Exogenous ketone salts inhibit superoxide production in the rat caudal solitary complex during exposure to normobaric and hyperbaric hyperoxia.

Hinojo CM, Ciarlone GE, D'Agostino DP, Dean JB · Journal of applied physiology (Bethesda, Md. : 1985) · 2021-03-04

Other

58. Boron-catalyzed dehydrative allylation of 1,3-diketones and β-ketone esters with 1,3-diarylallyl alcohols in water.

Zhang GM, Zhang H, Wang B, Wang JY · RSC advances · 2021-05-10

Systematic review / meta-analysis

59. [Systematic evaluation on efficacy and safety of Gingko Ketone Ester Dropping Pills in treatment of angina pectoris and coronary heart disease].

Wang KY, Wang HC, Jin XY, Zhang MY, Li N, Pang WT, Wang H, Zhang JH · Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica · 2021-05-28

Randomized clinical trial

60. A dietary ketone ester mitigates histological outcomes of NAFLD and markers of fibrosis in high-fat diet fed mice.

Moore MP, Cunningham RP, Davis RAH, Deemer SE, Roberts BM, Plaisance EP, Rector RS · American journal of physiology. Gastrointestinal and liver physiology · 2021-01-27

Observational human study

61. The Effects of a 6-Week Controlled, Hypocaloric Ketogenic Diet, With and Without Exogenous Ketone Salts, on Body Composition Responses.

Buga A, Kackley ML, Crabtree CD, Sapper TN, Mccabe L, Fell B, LaFountain RA, Hyde PN, Martini ER, Bowman J, Pan Y, Scandling D, Brownlow ML, O'Connor A, Simonetti OP, Kraemer WJ, Volek JS · Frontiers in nutrition · 2021-03-24

Other

62. Exogenous ketones in the healthy heart: the plot thickens.

Selvaraj S, Margulies KB · Cardiovascular research · 2020-10-19

Randomized clinical trial

63. Comparison of Ketogenic Diets with and without Ketone Salts versus a Low-Fat Diet: Liver Fat Responses in Overweight Adults.

Crabtree CD, Kackley ML, Buga A, Fell B, LaFountain RA, Hyde PN, Sapper TN, Kraemer WJ, Scandling D, Simonetti OP, Volek JS · Nutrients · 2021-03-17

Randomized clinical trial

64. Impact of Acutely Increased Endogenous- and Exogenous Ketone Bodies on FGF21 Levels in Humans.

Lauritzen ES, Svart MV, Voss T, Møller N, Bjerre M · Endocrine research · 2020-10-19

Preclinical / mechanistic

65. Ingested Ketone Ester Leads to a Rapid Rise of Acetyl-CoA and Competes with Glucose Metabolism in the Brain of Non-Fasted Mice.

Suissa L, Kotchetkov P, Guigonis JM, Doche E, Osman O, Pourcher T, Lindenthal S · International journal of molecular sciences · 2021-01-07

Clinical trial / intervention

66. Exogenous Ketones as Therapeutic Signaling Molecules in High-Stress Occupations: Implications for Mitigating Oxidative Stress and Mitochondrial Dysfunction in Future Research.

Waldman HS, McAllister MJ · Nutrition and metabolic insights · 2020-12-10

Preclinical / mechanistic

67. Neuroprotective effects of a ketogenic diet in combination with exogenous ketone salts following acute spinal cord injury.

Tan BT, Jiang H, Moulson AJ, Wu XL, Wang WC, Liu J, Plunet WT, Tetzlaff W · Neural regeneration research · 2020-04-05

Preclinical / mechanistic

68. The Effect of Exogenous Ketone Monoester Ingestion on Plasma BDNF During an Oral Glucose Tolerance Test.

Walsh JJ, Myette-Côté É, Little JP · Frontiers in physiology · 2020-09-09

Preclinical / mechanistic

69. Exogenous Dietary Ketone Ester Decreases Body Weight and Adiposity in Mice Housed at Thermoneutrality.

Deemer SE, Davis RAH, Roberts BM, Smith DL, Koutnik AP, Poff AM, D'Agostino DP, Plaisance EP · Obesity (Silver Spring, Md.) · 2020-07-02

Other

70. Nutritional Ketosis with Ketogenic Diets or Exogenous Ketones: Features, Convergence, and Divergence.

Poff AM, Koutnik AP, Egan B · Current sports medicine reports · 2020-07-22

Other

71. Iron-Catalyzed Cleavage Reaction of Keto Acids with Aliphatic Aldehydes for the Synthesis of Ketones and Ketone Esters.

Zhou F, Li L, Lin K, Zhang F, Deng GJ, Gong H · Chemistry (Weinheim an der Bergstrasse, Germany) · 2020-03-03

Other

72. Exogenous Ketone Salts Do Not Improve Cognitive Performance During a Dual-Stress Challenge.

Waldman HS, Shepherd BD, Egan B, McAllister MJ · International journal of sport nutrition and exercise metabolism · 2019-11-21

Preclinical / mechanistic

73. A Dietary Ketone Ester Normalizes Abnormal Behavior in a Mouse Model of Alzheimer's Disease.

Pawlosky RJ, Kashiwaya Y, King MT, Veech RL · International journal of molecular sciences · 2020-02-04

Preclinical / mechanistic

74. Inhibition of adenosine A1 receptors abolished the nutritional ketosis-evoked delay in the onset of isoflurane-induced anesthesia in Wistar Albino Glaxo Rijswijk rats.

Kovács Z, Brunner B, D'Agostino DP, Ari C · BMC anesthesiology · 2020-01-30

Randomized clinical trial

75. Gastrointestinal Effects of Exogenous Ketone Drinks are Infrequent, Mild, and Vary According to Ketone Compound and Dose.

Stubbs BJ, Cox PJ, Kirk T, Evans RD, Clarke K · International journal of sport nutrition and exercise metabolism · 2019-01-15

Review

76. Ketone Administration for Seizure Disorders: History and Rationale for Ketone Esters and Metabolic Alternatives.

Poff AM, Rho JM, D'Agostino DP · Frontiers in neuroscience · 2019-10-15

Other

77. Can ketone esters support an appetite to perform and recover?

Cervone DT, Hucik B, Wickham KA · The Journal of physiology · 2019-08-18

Preclinical / mechanistic

78. Concentration-Dependent Effects of a Dietary Ketone Ester on Components of Energy Balance in Mice.

Deemer SE, Davis RAH, Gower BA, Koutnik AP, Poff AM, Dickinson SL, Allison DB, D'Agostino DP, Plaisance EP · Frontiers in nutrition · 2019-05-01

Randomized clinical trial

79. Efficacy and safety of exogenous ketone bodies for preventive treatment of migraine: A study protocol for a single-centred, randomised, placebo-controlled, double-blind crossover trial.

Gross E, Putananickal N, Orsini AL, Schmidt S, Vogt DR, Cichon S, Sandor P, Fischer D · Trials · 2019-01-17

Preclinical / mechanistic

80. Preventive effects of ketone ester BD-AcAc2 on central nervous system oxygen toxicity and concomitant acute lung injury.

Yi H, Yu S, Zhang Y, Li R, Zhang D, Zhang D, Xu W · Diving and hyperbaric medicine · 2018-08-09

Preclinical / mechanistic

81. Nutritional ketosis delays the onset of isoflurane induced anesthesia.

Ari C, Kovács Z, Murdun C, Koutnik AP, Goldhagen CR, Rogers C, Diamond D, D'Agostino DP · BMC anesthesiology · 2018-07-18

Randomized clinical trial

82. Exogenous ketone salts do not improve cognitive responses after a high-intensity exercise protocol in healthy college-aged males.

Waldman HS, Basham SA, Price FG, Smith JW, Chander H, Knight AC, Krings BM, McAllister MJ · Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme · 2018-02-16

Other

83. The glucose-lowering effects of exogenous ketones: is there therapeutic potential?

Egan B · The Journal of physiology · 2018-03-24

Randomized clinical trial

84. A Ketone Ester Drink Lowers Human Ghrelin and Appetite.

Stubbs BJ, Cox PJ, Evans RD, Cyranka M, Clarke K, de Wet H · Obesity (Silver Spring, Md.) · 2017-11-06

Review

85. Exogenous Ketone Bodies as Promising Neuroprotective Agents for Developmental Brain Injury.

Wood TR, Stubbs BJ, Juul SE · Developmental neuroscience · 2019-05-14

Randomized clinical trial

86. On the Metabolism of Exogenous Ketones in Humans.

Stubbs BJ, Cox PJ, Evans RD, Santer P, Miller JJ, Faull OK, Magor-Elliott S, Hiyama S, Stirling M, Clarke K · Frontiers in physiology · 2017-10-30

Randomized clinical trial

87. A Ketone Ester Drink Increases Postexercise Muscle Glycogen Synthesis in Humans.

Holdsworth DA, Cox PJ, Kirk T, Stradling H, Impey SG, Clarke K · Medicine and science in sports and exercise · 2017-04-12

Randomized clinical trial

88. Intake of a Ketone Ester Drink during Recovery from Exercise Promotes mTORC1 Signaling but Not Glycogen Resynthesis in Human Muscle.

Vandoorne T, De Smet S, Ramaekers M, Van Thienen R, De Bock K, Clarke K, Hespel P · Frontiers in physiology · 2017-05-23

Preclinical / mechanistic

89. Novel ketone body therapy for managing Alzheimer's disease: An Editorial Highlight for Effects of a dietary ketone ester on hippocampal glycolytic and tricarboxylic acid cycle intermediates and amino acids in a 3xTgAD mouse model of Alzheimer's disease.

Puchowicz MA, Seyfried TN · Journal of neurochemistry · 2017-03-15

Preclinical / mechanistic

90. Effects of a dietary ketone ester on hippocampal glycolytic and tricarboxylic acid cycle intermediates and amino acids in a 3xTgAD mouse model of Alzheimer's disease.

Pawlosky RJ, Kemper MF, Kashiwaya Y, King MT, Mattson MP, Veech RL · Journal of neurochemistry · 2017-03-15

Other

91. Mg(OMe)2 promoted allylic isomerization of γ-hydroxy-α,β-alkenoic esters to synthesize γ-ketone esters.

Lai L, Li AN, Zhou J, Guo Y, Lin L, Chen W, Wang R · Organic & biomolecular chemistry · 2017-02-22

Preclinical / mechanistic

92. Anticonvulsant properties of an oral ketone ester in a pentylenetetrazole-model of seizure.

Viggiano A, Pilla R, Arnold P, Monda M, D'Agostino D, Coppola G · Brain research · 2015-05-27

Case report / case series

93. A new way to produce hyperketonemia: use of ketone ester in a case of Alzheimer's disease.

Newport MT, VanItallie TB, Kashiwaya Y, King MT, Veech RL · Alzheimer's & dementia : the journal of the Alzheimer's Association · 2014-10-07

Review

95. Ketone body therapy: from the ketogenic diet to the oral administration of ketone ester.

Hashim SA, VanItallie TB · Journal of lipid research · 2014-03-05

Review

96. Ketone esters increase brown fat in mice and overcome insulin resistance in other tissues in the rat.

Veech RL · Annals of the New York Academy of Sciences · 2013-08-02

Preclinical / mechanistic

97. A ketone ester diet exhibits anxiolytic and cognition-sparing properties, and lessens amyloid and tau pathologies in a mouse model of Alzheimer's disease.

Kashiwaya Y, Bergman C, Lee JH, Wan R, King MT, Mughal MR, Okun E, Clarke K, Mattson MP, Veech RL · Neurobiology of aging · 2012-12-29

Preclinical / mechanistic

98. Therapeutic ketosis with ketone ester delays central nervous system oxygen toxicity seizures in rats.

D'Agostino DP, Pilla R, Held HE, Landon CS, Puchowicz M, Brunengraber H, Ari C, Arnold P, Dean JB · American journal of physiology. Regulatory, integrative and comparative physiology · 2013-04-03

Preclinical / mechanistic

99. Mitochondrial biogenesis and increased uncoupling protein 1 in brown adipose tissue of mice fed a ketone ester diet.

Srivastava S, Kashiwaya Y, King MT, Baxa U, Tam J, Niu G, Chen X, Clarke K, Veech RL · FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2012-02-23

Other

100. Reduction of exogenous ketones depends upon NADPH generated photosynthetically in cells of the cyanobacterium Synechococcus PCC 7942.

Yamanaka R, Nakamura K, Murakami A · AMB Express · 2011-09-01

Preclinical / mechanistic

101. A ketone ester diet increases brain malonyl-CoA and Uncoupling proteins 4 and 5 while decreasing food intake in the normal Wistar Rat.

Kashiwaya Y, Pawlosky R, Markis W, King MT, Bergman C, Srivastava S, Murray A, Clarke K, Veech RL · The Journal of biological chemistry · 2010-06-07

Other

102. Modification of haloalkane-induced hepatotoxicity by exogenous ketones and metabolic ketosis.

Hewitt WR, Miyajima H, Côté MG, Plaa GL · Federation proceedings · 1980-11-01

Preclinical / mechanistic

103. Ketogenic diet and ketone salts differentially improve cardiometabolic complications in an HFpEF rat model.

Gonçalves A, Alves IN, Mendes C, Miranda D, Conceição G, Almeida-Coelho J, Martins D, Miranda I, Rodrigues A, Silva C, Oliveira SM, Sereno J, Ferreira MJ, Dischinger U, Girão H, Leite-Moreira AF, Sequeira V, Falcão-Pires I · The Journal of physiology · 2025-04-03

Randomized clinical trial

104. Crossover Trial of Exogenous Ketones on Cardiometabolic Endpoints in Heart Failure With Preserved Ejection Fraction.

Selvaraj S, Karaj A, Chirinos JA, Denney N, Grosso G, Fernando M, Chambers K, Demastus C, Reddy R, Langham M, Kumar D, Maynard H, Pourmussa B, Prenner SB, Cohen JB, Ischiropoulos H, Rickels MR, Poole DC, Church DD, Wolfe RR, Kelly DP, Putt M, Margulies KB, Zamani P · JACC. Heart failure · 2025-03-29

Randomized clinical trial

105. Effect of Exogenous Ketones as an Adjunct to Low-Calorie Diet on Metabolic Markers.

Roeth EJ, Parker G, Cooper-Leavitt EF, Beus CG, Braithwaite CR, Morris MD, Reynolds AP, Evans EP, Radford JH, Davis FD, Reynolds PR, Parrish RR, Bikman BT · Nutrients · 2025-11-16

Randomized clinical trial

106. Potential therapeutic benefit of exogenous ketone ester administration in delirium: a narrative review.

Smith R, Harrison F, Bastarache J, Williams Roberson S, Zaganjor E, Pandharipande P, Rice T, Ely W · Critical care (London, England) · 2025-10-07

Other

107. Practical challenges and ethical considerations in treating early-onset MADD with exogenous ketones.

LoPiccolo MK, Van Hove JLK · Molecular genetics and metabolism · 2025-08-27

Other

108. Synthesis and Antifungal Activity of Raspberry Ketone Ester Derivatives as Potential Fungicides.

Shu L, Wei Z, Wang Y, Li Y, Zhao Y, Tian Y, Qian L, Chen G, Liu S, Huang X, Hao N, Che Z · Chemistry & biodiversity · 2025-04-26

Randomized clinical trial

109. Ketone ester ingestion increases exogenous carbohydrate storage and lowers glycemia during post-exercise recovery: a randomised crossover trial.

Clarke L, Russell SL, Spellanzon B, Maher JL, Betts JA, Gonzalez JT · European journal of nutrition · 2025-08-12

Randomized clinical trial

110. Ginkgo ketone ester tablets for the treatment of cognitive impairment associated with chemotherapy for breast cancer - a prospective cohort study.

Chen J, Chen L, Jiang K, Wang D, Wu C, Qin Y, Liu S · Frontiers in pharmacology · 2025-07-21

Randomized clinical trial

111. Effectiveness of Exogenous Ketone Salts in Enhancing Circulating Acetoacetate Levels-A Pilot Study in Healthy Adults.

Holland-Winkler AM, Moore AR, Bederman I · Nutrients · 2025-05-14

Systematic review / meta-analysis

112. Symptoms during initiation of a ketogenic diet: a scoping review of occurrence rates, mechanisms and relief strategies.

Skartun O, Smith CR, Laupsa-Borge J, Dankel SN · Frontiers in nutrition · 2025-03-26

Preclinical / mechanistic

113. Characterizing the Hepatic Metabolic Pathway of Ketone Ester and Subsequent Metabolites Using Human and Rat Liver Fractions.

Panse N, Gerk PM · The AAPS journal · 2025-03-14

Systematic review / meta-analysis

114. Efficacy and Safety of Exogenous Ketones in People with Mild Neurocognitive Disorder and Alzheimer's Disease: A Systematic Literature Review.

Krolak-Salmon P, Swerdlow RH, Mastain T, Dive-Pouletty C, Pooley N, Kisomi M · Nutrition reviews · 2025-02-12

Medium-Chain Triglycerides (MCT) Recent peer-reviewed literature

Expanded source-audited selection from the connected PDF archive. Recent reviews and human studies are placed before older or more mechanistic work.

Human clinical study

1. Supplementation with medium-chain fatty acids increases body weight loss during very low-calorie ketogenic diet

Original publication title: Supplementation with medium-chain fatty acids increases body weight loss during very low-calorie ketogenic diet

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Human study

2. Supplementation of Regular Diet With Medium-Chain Triglycerides for Procognitive Effects

Original publication title: Supplementation of Regular Diet With Medium-Chain Triglycerides for Procognitive Effects

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Human metabolic study

3. Ketogenic Effects of Multiple Doses of a Medium-Chain Triglyceride Supplement

Original publication title: Ketogenic Effects of Multiple Doses of a Medium-Chain Triglyceride Supplement

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Clinical study

4. Effects of a Ketogenic Diet Containing Medium-Chain Triglycerides

Original publication title: Effects of a Ketogenic Diet Containing Medium-Chain Triglycerides

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Human metabolic study

5. Tricaprylin Alone Increases Plasma Ketone Concentrations

Original publication title: Tricaprylin Alone Increases Plasma Ketone Concentrations

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Human metabolic study

6. Ketosis After Intake of Coconut Oil

Original publication title: Ketosis After Intake of Coconut Oil

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Systematic review / meta-analysis

7. Impact of medium-chain triglyceride with and without ketogenic diet in the management of drug-resistant epilepsy: a systematic review.

Pellizzari M, De Clauser L, Mir-Majidi S, Leone A, Veggiotti P, Previtali R, Olivotto S, Bertoli S, De Amicis R · Nutritional neuroscience · 2026-08-20

Preclinical / mechanistic

8. The impact of medium chain triglyceride ketogenic diet on liver mitochondria and cytochrome P450 2E1.

Ryan AS, Roberts RM, Stayer KM, Tomasevich AA, Misare KR, Hollis F, McQuail JA, Hartman JH · Archives of biochemistry and biophysics · 2026-08-19

Randomized clinical trial

9. Ketogenic effects of milk protein-coated medium-chain triglycerides in healthy men: A randomized, double-blind, crossover study.

Ito K, Kawasaki Y, Tamura K, Nakamura K, Kawai Y, Watanabe T · PloS one · 2026-08-10

Randomized clinical trial

10. Metabolic Therapy in Glioblastoma-Mapping the Evidence for Ketogenic Diet as an Adjunctive Strategy.

Wiśniewska D, Winiarska M, Krupa-Nurcek S · Nutrients · 2026-08-03

Clinical trial / intervention

11. Use of medium-chain triglycerides in paediatric patients with drug-resistant epilepsy without ketogenic therapy.

Viollaz R, Alberti MJ, de Clauser L, Vilavedra JF · Epilepsy & behavior : E&B · 2026-06-12

Case report / case series

12. Reversible high-fat ketogenic formula-induced hypertriglyceridemia in a child with NALCN mutation on a ketogenic diet: a case report.

Elbarky A, Dawoud H, Elballat KE, Gamal H, Salamah A · Molecular biology reports · 2026-05-20

Systematic review / meta-analysis

13. Exploring the rise of the ketogenic dietary therapies for epilepsy in Latin America: A systematic review and meta-analysis.

Shibaki R, de Oliveira Franco MDNS, Camargo JSL, Citro GM, Ramos EM, Bruzzone M · Epilepsy research · 2026-04-30

Other

14. Can Artificial Intelligence Chatbots Plan Therapeutic Ketogenic Diets for Children With Epilepsy?

Ajmera F, Lowe H, Dickson J, Owusu K, Zak M, Sharma S · Journal of human nutrition and dietetics : the official journal of the British Dietetic Association · 2026-04-13

Other

15. Investigation of the implementation and utilization of ketogenic diet therapy in China : For the Commission on Standardized Development of Epilepsy Centers and Commission on Ketogenic Diet, China Association Against Epilepsy.

Xi W, Lin Y, Tian S, Liao J, Wang Y · Acta epileptologica · 2026-04-01

Preclinical / mechanistic

16. Primary components of MCT ketogenic diet are detrimental to bone loss associated with accelerated aging and age-related neurotoxicity in mice.

Jain S, Vohora D · Bone · 2024-12-26

Review

17. The Cardioprotective Effects of Nutritional Ketosis: Mechanisms and Clinical Implications.

Venturini C, Mancinelli L, Matacchione G, Olivieri F, Antonicelli R · Nutrients · 2024-12-05

Preclinical / mechanistic

18. Oral Administration of a Novel, Synthetic Ketogenic Compound Elevates Blood β-Hydroxybutyrate Levels in Mice in Both Fasted and Fed Conditions.

Soliven MA, Rogers CQ, Williams MS, Thomas NN, Turos E, D'Agostino DP · Nutrients · 2024-10-18

Clinical trial / intervention

19. Ketogenic effect of coconut oil in ALS patients.

Carrera-Juliá S, Obrador E, López-Blanch R, Oriol-Caballo M, Moreno-Murciano P, Estrela JM · Frontiers in nutrition · 2024-07-17

Randomized clinical trial

20. A randomized feasibility trial of medium chain triglyceride-supplemented ketogenic diet in people with Parkinson's disease.

Choi AH, Delgado M, Chen KY, Chung ST, Courville A, Turner SA, Yang S, Airaghi K, Dustin I, McGurrin P, Wu T, Hallett M, Ehrlich DJ · BMC neurology · 2024-04-01

Preclinical / mechanistic

21. A High MCT-Based Ketogenic Diet Suppresses Th1 and Th17 Responses to Ameliorate Experimental Autoimmune Encephalomyelitis in Mice by Inhibiting GSDMD and JAK2-STAT3/4 Pathways.

Zhang Q, Sun W, Wang Q, Zheng X, Zhang R, Zhang N · Molecular nutrition & food research · 2023-12-06

Other

22. Is there evidence of a ketogenic effect of coconut oil? Commentary: Effect of the Mediterranean diet supplemented with nicotinamide riboside and pterostilbene and/or coconut oil on anthropometric variables in amyotrophic lateral sclerosis. A pilot study.

Norgren J, Kåreholt I, Sindi S · Frontiers in nutrition · 2024-01-08

Randomized clinical trial

23. Ketogenic effects of medium chain triglycerides containing formula and its correlation to breath acetone in healthy volunteers: a randomized, double-blinded, placebo-controlled, single dose-response study.

Nakamura K, Hagihara K, Nagai N, Egashira R, Takeuchi M, Nakano M, Saito H, Moriguchi M, Tonari S, Fujii H, Miyake A, Omae Y, Ashida K · Frontiers in nutrition · 2023-09-27

Preclinical / mechanistic

24. Neuroprotective effect of a medium-chain triglyceride ketogenic diet on MPTP-induced Parkinson's disease mice: a combination of transcriptomics and metabolomics in the substantia nigra and fecal microbiome.

Zhang W, Chen S, Huang X, Tong H, Niu H, Lu L · Cell death discovery · 2023-07-17

Clinical trial / intervention

25. Refueling the post COVID-19 brain: potential role of ketogenic medium chain triglyceride supplementation: an hypothesis.

Juby AG, Cunnane SC, Mager DR · Frontiers in nutrition · 2023-06-21

Observational human study

26. Comprehensive study of metabolic changes induced by a ketogenic diet therapy using GC/MS- and LC/MS-based metabolomics.

Akiyama M, Akiyama T, Saigusa D, Hishinuma E, Matsukawa N, Shibata T, Tsuchiya H, Mori A, Fujii Y, Mogami Y, Tokorodani C, Kuwahara K, Numata-Uematsu Y, Inoue K, Kobayashi K · Seizure · 2023-03-16

Other

27. Effect of a Ketogenic Medium Chain Triglyceride-Enriched Diet on the Fecal Microbiota in Canine Idiopathic Epilepsy: A Pilot Study.

García-Belenguer S, Grasa L, Palacio J, Moral J, Rosado B · Veterinary sciences · 2023-03-24

Other

28. Beta-Hydroxybutyrate (BHB), Glucose, Insulin, Octanoate (C8), and Decanoate (C10) Responses to a Medium-Chain Triglyceride (MCT) Oil with and without Glucose: A Single-Center Study in Healthy Adults.

Heidt C, Fobker M, Newport M, Feldmann R, Fischer T, Marquardt T · Nutrients · 2023-02-24

Clinical trial / intervention

29. [Beneficial effects of ketogenic diet for Alzheimer's disease management].

Charlot A, Lernould A, Plus I, Zoll J · Biologie aujourd'hui · 2023-11-29

Preclinical / mechanistic

30. Ketogenic diet containing medium-chain triglyceride ameliorates transcriptome disruption in skeletal muscles of rat models of duchenne muscular dystrophy.

Fujikura Y, Yamanouchi K, Sugihara H, Hatakeyama M, Abe T, Ato S, Oishi K · Biochemistry and biophysics reports · 2022-11-11

Review

31. Ketogenic Diets in the Management of Lennox-Gastaut Syndrome-Review of Literature.

Skrobas U, Duda P, Bryliński Ł, Drożak P, Pelczar M, Rejdak K · Nutrients · 2022-11-23

Preclinical / mechanistic

32. A medium-chain triglyceride containing ketogenic diet exacerbates cardiomyopathy in a CRISPR/Cas9 gene-edited rat model with Duchenne muscular dystrophy.

Fujikura Y, Kimura K, Yamanouchi K, Sugihara H, Hatakeyama M, Zhuang H, Abe T, Daimon M, Morita H, Komuro I, Oishi K · Scientific reports · 2022-07-08

Observational human study

33. Ketonuria and Seizure Control in the Medium Chain Triglyceride and Classic Ketogenic Diets.

Lowe H, Keller AE, Tanzini E, Aimola S, Liu YMC, Zak M, Chan V, Kobayashi J, Donner EJ · The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques · 2021-06-02

Randomized clinical trial

34. Ketogenic Effects of Multiple Doses of a Medium Chain Triglycerides Enriched Ketogenic Formula in Healthy Men under the Ketogenic Diet: A Randomized, Double-Blinded, Placebo-Controlled Study.

Nakamura K, Hagihara K, Nagai N, Egashira R, Takeuchi M, Nakano M, Saito H, Moriguchi M, Tonari S, Watanabe S, Miyake A, Ashida K · Nutrients · 2022-03-12

Other

35. Medium-chain Triglyceride Ketogenic Diet as a Treatment Strategy for Adult Super-refractory Status Epilepticus.

Dutta K, Satishchandra P, Borkotokey M · Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2022-02-03

Review

36. Alzheimer's Disease and Type 2 Diabetes Mellitus: The Use of MCT Oil and a Ketogenic Diet.

Takeishi J, Tatewaki Y, Nakase T, Takano Y, Tomita N, Yamamoto S, Mutoh T, Taki Y · International journal of molecular sciences · 2021-11-15

Preclinical / mechanistic

37. Ketogenic diet with medium-chain triglycerides restores skeletal muscle function and pathology in a rat model of Duchenne muscular dystrophy.

Fujikura Y, Sugihara H, Hatakeyama M, Oishi K, Yamanouchi K · FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2021-07-16

Clinical trial / intervention

38. Emerging Role of the Ketogenic Dietary Therapies beyond Epilepsy in Child Neurology.

Kapoor D, Garg D, Sharma S · Annals of Indian Academy of Neurology · 2021-05-11

Clinical trial / intervention

39. The possibility of use of the ketogenic diet and medium chain triglycerides supplementation in the support therapy of Alzheimer disease.

Włodarek D · Current opinion in clinical nutrition and metabolic care · 2021-03-21

Clinical trial / intervention

40. The Feasibility and Tolerability of Medium Chain Triglycerides in Women with a Catamenial Seizure Pattern on the Modified Atkins Diet.

Felton EA, Henry-Barron BJ, Jan AK, Shegelman A, Faltersack K, Vizthum D, Cervenka MC · Nutrients · 2021-06-30

Randomized clinical trial

41. An fMRI Investigation into the Effects of Ketogenic Medium-Chain Triglycerides on Cognitive Function in Elderly Adults: A Pilot Study.

Yomogida Y, Matsuo J, Ishida I, Ota M, Nakamura K, Ashida K, Kunugi H · Nutrients · 2021-06-22

Preclinical / mechanistic

42. Octanoic acid a major component of widely consumed medium-chain triglyceride ketogenic diet is detrimental to bone.

Jain S, Rai R, Singh D, Vohora D · Scientific reports · 2021-03-26

Systematic review / meta-analysis

43. Use of ketogenic diets in the treatment of central nervous system diseases: a systematic review.

Christensen MG, Damsgaard J, Fink-Jensen A · Nordic journal of psychiatry · 2020-08-06

Randomized clinical trial

44. A Modified MCT-Based Ketogenic Diet Increases Plasma β-Hydroxybutyrate but Has Less Effect on Fatigue and Quality of Life in People with Multiple Sclerosis Compared to a Modified Paleolithic Diet: A Waitlist-Controlled, Randomized Pilot Study.

Lee JE, Titcomb TJ, Bisht B, Rubenstein LM, Louison R, Wahls TL · Journal of the American College of Nutrition · 2020-03-26

Preclinical / mechanistic

45. The Effects of a Ketogenic Medium-Chain Triglyceride Diet on the Feces in Dogs With Idiopathic Epilepsy.

Pilla R, Law TH, Pan Y, Zanghi BM, Li Q, Want EJ, Lidbury JA, Steiner JM, Suchodolski JS, Volk HA · Frontiers in veterinary science · 2020-12-22

Clinical trial / intervention

46. Nutritional ketosis as an intervention to relieve astrogliosis: Possible therapeutic applications in the treatment of neurodegenerative and neuroprogressive disorders.

Morris G, Maes M, Berk M, Carvalho AF, Puri BK · European psychiatry : the journal of the Association of European Psychiatrists · 2020-01-31

Preclinical / mechanistic

47. Inhibition of adenosine A1 receptors abolished the nutritional ketosis-evoked delay in the onset of isoflurane-induced anesthesia in Wistar Albino Glaxo Rijswijk rats.

Kovács Z, Brunner B, D'Agostino DP, Ari C · BMC anesthesiology · 2020-01-30

Randomized clinical trial

48. Metabolic and Immunological Effects of Intermittent Fasting on a Ketogenic Diet Containing Medium-Chain Triglycerides in Healthy Dogs.

Leung YB, Cave NJ, Heiser A, Edwards PJB, Godfrey AJR, Wester T · Frontiers in veterinary science · 2020-01-08

Observational human study

49. Medium-chain triglyceride ketogenic diet is effective for treatment of an adult with super-refractory status epilepticus: a case report and literature review.

Prasoppokakorn T, Jirasakuldej S, Lakananurak N · European journal of clinical nutrition · 2019-07-17

Clinical trial / intervention

50. An Experimental Ketogenic Diet for Alzheimer Disease Was Nutritionally Dense and Rich in Vegetables and Avocado.

Taylor MK, Swerdlow RH, Burns JM, Sullivan DK · Current developments in nutrition · 2019-02-20

Randomized clinical trial

51. Effects of a medium-chain triglyceride-based ketogenic formula on cognitive function in patients with mild-to-moderate Alzheimer's disease.

Ota M, Matsuo J, Ishida I, Takano H, Yokoi Y, Hori H, Yoshida S, Ashida K, Nakamura K, Takahashi T, Kunugi H · Neuroscience letters · 2018-10-24

Randomized clinical trial

52. The Effect of Medium Chain Triglycerides on Time to Nutritional Ketosis and Symptoms of Keto-Induction in Healthy Adults: A Randomised Controlled Clinical Trial.

D C Harvey CJ, Schofield GM, Williden M, McQuillan JA · Journal of nutrition and metabolism · 2018-05-22

Clinical trial / intervention

53. A modified ketogenic gluten-free diet with MCT improves behavior in children with autism spectrum disorder.

Lee RWY, Corley MJ, Pang A, Arakaki G, Abbott L, Nishimoto M, Miyamoto R, Lee E, Yamamoto S, Maunakea AK, Lum-Jones A, Wong M · Physiology & behavior · 2018-02-05

Randomized clinical trial

54. Ketogenic Diet Based on Extra Virgin Coconut Oil Has No Effects in Young Wistar Rats With Pilocarpine-Induced Epilepsy.

Melo IT, M Rêgo E, Bueno NB, Gomes TC, Oliveira SL, Trindade-Filho EM, Cabral CR, Machado TS, Galvão JA, R Ataide T · Lipids · 2018-03-23

Clinical trial / intervention

55. Ketogenic Medium Chain Triglycerides Increase Brain Energy Metabolism in Alzheimer's Disease.

Croteau E, Castellano CA, Richard MA, Fortier M, Nugent S, Lepage M, Duchesne S, Whittingstall K, Turcotte ÉE, Bocti C, Fülöp T, Cunnane SC · Journal of Alzheimer's disease : JAD · 2018-06-20

Preclinical / mechanistic

56. A ketogenic diet supplemented with medium-chain triglycerides enhances the anti-tumor and anti-angiogenic efficacy of chemotherapy on neuroblastoma xenografts in a CD1-nu mouse model.

Aminzadeh-Gohari S, Feichtinger RG, Vidali S, Locker F, Rutherford T, O'Donnel M, Stöger-Kleiber A, Mayr JA, Sperl W, Kofler B · Oncotarget · 2017-08-08

Other

57. Neuronal decanoic acid oxidation is markedly lower than that of octanoic acid: A mechanistic insight into the medium-chain triglyceride ketogenic diet.

Khabbush A, Orford M, Tsai YC, Rutherford T, O'Donnell M, Eaton S, Heales SJR · Epilepsia · 2017-07-06

Other

58. Emulsification Increases the Acute Ketogenic Effect and Bioavailability of Medium-Chain Triglycerides in Humans: Protein, Carbohydrate, and Fat Metabolism.

Courchesne-Loyer A, Lowry CM, St-Pierre V, Vandenberghe C, Fortier M, Castellano CA, Wagner JR, Cunnane SC · Current developments in nutrition · 2017-06-21

Other

59. Outcome of ketogenic diets in GLUT1 deficiency syndrome in Japan: A nationwide survey.

Fujii T, Ito Y, Takahashi S, Shimono K, Natsume J, Yanagihara K, Oguni H · Brain & development · 2016-02-26

Other

60. Effectiveness of Medium Chain Triglyceride Ketogenic Diet in Thai Children with Intractable Epilepsy.

Chomtho K, Suteerojntrakool O, Chomtho S · Journal of the Medical Association of Thailand = Chotmaihet thangphaet · 2016-06-03

Other

61. A fatty acid in the MCT ketogenic diet for epilepsy treatment blocks AMPA receptors.

Rogawski MA · Brain : a journal of neurology · 2016-02-26

Observational human study

62. The MCT-ketogenic diet as a treatment option in refractory childhood epilepsy: A prospective study with 2-year follow-up.

Lambrechts DA, de Kinderen RJ, Vles HS, de Louw AJ, Aldenkamp AP, Majoie MJ · Epilepsy & behavior : E&B · 2015-08-24

Observational human study

63. Ten-year single-center experience of the ketogenic diet: factors influencing efficacy, tolerability, and compliance.

Wibisono C, Rowe N, Beavis E, Kepreotes H, Mackie FE, Lawson JA, Cardamone M · The Journal of pediatrics · 2015-01-30

Clinical trial / intervention

64. Growth of human colon cancer cells in nude mice is delayed by ketogenic diet with or without omega-3 fatty acids and medium-chain triglycerides.

Hao GW, Chen YS, He DM, Wang HY, Wu GH, Zhang B · Asian Pacific journal of cancer prevention : APJCP · 2015-03-17

Preclinical / mechanistic

65. Anticonvulsant profile of caprylic acid, a main constituent of the medium-chain triglyceride (MCT) ketogenic diet, in mice.

Wlaź P, Socała K, Nieoczym D, Łuszczki JJ, Zarnowska I, Zarnowski T, Czuczwar SJ, Gasior M · Neuropharmacology · 2011-12-17

Randomized clinical trial

66. The effect of the classical and medium chain triglyceride ketogenic diet on vitamin and mineral levels.

Christodoulides SS, Neal EG, Fitzsimmons G, Chaffe HM, Jeanes YM, Aitkenhead H, Cross JH · Journal of human nutrition and dietetics : the official journal of the British Dietetic Association · 2011-05-27

Preclinical / mechanistic

67. A ketogenic diet increases succinic dehydrogenase (SDH) activity and recovers age-related decrease in numeric density of SDH-positive mitochondria in cerebellar Purkinje cells of late-adult rats.

Balietti M, Giorgetti B, Di Stefano G, Casoli T, Platano D, Solazzi M, Bertoni-Freddari C, Aicardi G, Lattanzio F, Fattoretti P · Micron (Oxford, England : 1993) · 2009-10-08

Review

68. Medium-chain triglyceride (MCT) ketogenic therapy.

Liu YM · Epilepsia · 2008-12-17

Other

69. Growth of children on classical and medium-chain triglyceride ketogenic diets.

Neal EG, Chaffe HM, Edwards N, Lawson MS, Schwartz RH, Cross JH · Pediatrics · 2008-08-05

Preclinical / mechanistic

70. Ketogenic diets cause opposing changes in synaptic morphology in CA1 hippocampus and dentate gyrus of late-adult rats.

Balietti M, Giorgetti B, Fattoretti P, Grossi Y, Di Stefano G, Casoli T, Platano D, Solazzi M, Orlando F, Aicardi G, Bertoni-Freddari C · Rejuvenation research · 2008-07-03

Randomized clinical trial

71. A prospective study: growth and nutritional status of children treated with the ketogenic diet.

Liu YM, Williams S, Basualdo-Hammond C, Stephens D, Curtis R · Journal of the American Dietetic Association · 2003-06-05

Preclinical / mechanistic

72. Dietary fat, ketosis, and seizure resistance in rats on the ketogenic diet.

Likhodii SS, Musa K, Mendonca A, Dell C, Burnham WM, Cunnane SC · Epilepsia · 2000-11-15

Other

73. Dietary practices and use of the ketogenic diet in the UK.

Magrath G, MacDonald A, Whitehouse W · Seizure · 2000-06-14

Preclinical / mechanistic

74. The MCT ketogenic diet: effects on animal seizure models.

Thavendiranathan P, Mendonca A, Dell C, Likhodii SS, Musa K, Iracleous C, Cunnane SC, Burnham WM · Experimental neurology · 2000-02-25

Review

75. The ketogenic diet: a practical guide for caregivers.

Carroll J, Koenigsberger D · Journal of the American Dietetic Association · 1998-03-21

Other

76. Management of intractable childhood seizures using the non-MCT oil ketogenic diet in 20 patients.

Edelstein SF, Chisholm M · Journal of the American Dietetic Association · 1996-11-01

Review

77. Implementing a ketogenic diet based on medium-chain triglyceride oil in pediatric patients with cancer.

Nebeling LC, Lerner E · Journal of the American Dietetic Association · 1995-06-01

Preclinical / mechanistic

78. Effects of ketogenic diet on electroconvulsive threshold and brain contents of adenosine nucleotides.

Nakazawa M, Kodama S, Matsuo T · Brain & development · 1983-01-01

Other

79. Effect of ketogenic diets in gestation on some characteristics of carbohydrate metabolism in fetal pig brain and liver.

Rosebrough RW, Steele NC, Frobish LT · Growth · 1981-01-01

Other

80. Medium chain triglyceride oil ketogenic diets in the treatment of childhood epilepsy.

Clark BJ, House FM · Journal of human nutrition · 1978-04-01

Other

81. Medium-chain triglycerides in a ketogenic diet.

Stephenson JB, House FM, Stromberg P · Developmental medicine and child neurology · 1977-10-01

Preclinical / mechanistic

82. Ketogenic response to medium-chain triglyceride load in the rat.

Bach A, Schirardin H, Weryha A, Bauer M · The Journal of nutrition · 1977-10-01

Preclinical / mechanistic

83. Experimental hyperosmolar diabetic syndrome. Ketogenic response to medium-chain triglycerides.

Gordon EE, Duga J · Diabetes · 1975-03-01

Other

84. Ketogenic diet containing medium-chain triglycerides.

Signore JM · Journal of the American Dietetic Association · 1973-03-01

Clinical trial / intervention

85. Medium-chain triglycerides and ketogenic diet prevent alterations of the gut microbiome in transgenic Alzheimer's disease mice.

M'Bra PEH, Suárez-Uribe I, Avino M, Ng Kwan Lim E, Mayhue M, Balthazar P, Aumont A, Prévost K, Massé E, Fernandes KJL · Communications biology · 2025-12-07

Clinical trial / intervention

86. Exploring the Facilitators and Barriers of Adherence to Mediterranean-Ketogenic Dietary Interventions in Parkinson's Disease: A Qualitative Study.

Tosefsky KN, Wang YN, Lam JS, Cohen TR, Appel-Cresswell S · Current developments in nutrition · 2025-10-30

Review

87. The Ketogenic Diet Through a Metabolomic Lens: Biochemical Pathways, Therapeutic Applications, and Analytical Challenges.

Idzikowska K, Gątarek P, Gajda A, Safiński P, Przyslo L, Kałużna-Czaplińska J · Nutrients · 2025-09-16

Systematic review / meta-analysis

88. Symptoms during initiation of a ketogenic diet: a scoping review of occurrence rates, mechanisms and relief strategies.

Skartun O, Smith CR, Laupsa-Borge J, Dankel SN · Frontiers in nutrition · 2025-03-26

Supplementation & Nutraceuticals Recent peer-reviewed literature

Source-audited selection from the connected PDF archive. Systematic reviews/meta-analyses and recent human evidence are prioritized when available; sparse areas are explicitly kept sparse.

Human cross-sectional study

1. Low Thiamine Status in Adults Following Low-Carbohydrate Ketogenic Diets: A Cross-Sectional Comparative Study of Micronutrient Intake and Status

Original publication title: Low Thiamine Status in Adults Following Low-Carbohydrate Ketogenic Diets: A Cross-Sectional Comparative Study of Micronutrient Intake and Status

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Supplementation review

2. Beneficial Effects of Exogenous Ketogenic Supplements on Aging Processes and Age-Related Neurodegenerative Diseases

Original publication title: Beneficial Effects of Exogenous Ketogenic Supplements on Aging Processes and Age-Related Neurodegenerative Diseases

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Randomized clinical trial

3. Supplementation With Ketogenic Precursors Enhances Virtual Reality Shooting Performance During Sleep Restriction: A Randomized, Placebo-Controlled, Crossover Trial.

Buga A, Stoner JT, Sapper TN, Crabtree CD, Decker DD, Robinson BT, Kackley ML, McClure T, Chebbi A, Stalter H, Dawson L, Whiteman A, Spencer M, Lane L, Hayes SM, Mindel J, Kraemer WJ, Volek JS · Military medicine · 2026-09-17

Preclinical / mechanistic

4. Ketone ester alleviates sepsis-associated liver injury through β-hydroxybutyrylation of STAT1.

Bai Y, Li K, Zhu D, Li R, Yan Y, Zhong C, Zha L, Wang Q · Immunobiology · 2026-09-11

Other

5. Ketone Ester Intake Did Not Improve Performance, Neither Cognitive Function or Sleep, During an 8-Day Simulated Cycling Race.

Engelbrecht L, Lauriks W, Robberechts R, Stalmans M, Ramaekers M, Terblanche E, Koppo K, Poffé C · Medicine and science in sports and exercise · 2026-08-27

Case report / case series

6. Management of ketogenic diet therapy in patients with ileostomy: A report of 2 cases.

Baker BJ, Olbina AE, Godfrey MA, Graber AE, Parrish TN, Delima SIR · Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition · 2026-08-25

Clinical trial / intervention

7. Ketogenic Diet as an Adjuvant in Epithelial Cancers: Mechanisms, Model Systems, and Translational Opportunities.

Ylikomi T, Nees M · Cancers · 2026-08-12

Observational human study

8. Continuing Ketogenic Diet Therapy in Setting of Hypercalcemia.

Sarabia L, Wetzel A, Sawyer J, Giannini S, Imel E, Delima SI · Journal of child neurology · 2026-07-30

Randomized clinical trial

9. Acute 1,3-Butanediol Co-Ingestion with Carbohydrate Does Not Improve Endurance Performance in Chronically Ketogenic Male Athletes.

Carpenter M, Brouner J, Spendiff O · Nutrients · 2026-07-22

Other

10. Integrated UPLC-MS/MS with interpretable artificial intelligence-enhanced Raman and near-infrared spectroscopy for multi-objective monitoring of ginkgo ketone ester tablets column purification.

Zhou Q, Jiang M, Wang D, Wang J, Tao Y · Journal of pharmaceutical and biomedical analysis · 2026-07-17

Clinical trial / intervention

11. Telehealth-Based Ketogenic Metabolic Therapy With Lifestyle Interventions for Post-viral Illness: A Research Brief of Patients' Experiences.

Colgan DD, Stadler DD, Grow T, Ruddick M, Weimbs T, Davenport TE, Zwickey H · Journal of patient experience · 2026-07-05

Clinical trial / intervention

12. Halting cyst progression in ADPKD using long-term ketogenic metabolic therapy and supplementation with exogenous ketones and alkaline citrate-a case series.

Messing M, Muensterman E, Marcon S, Weimbs T · Frontiers in nutrition · 2026-06-29

Other

13. Critical Nutrients in the Ketogenic Diet for Adolescents Based on Optimized Hypothetical Meal Plans.

Assmann M, Albrecht I, Fischer T · Nutrients · 2026-06-27

Review

14. Ketone bodies in kidney diseases: novel insights.

Dai W, Zhang W, Li H, Gao Y, Xiao L, Chen Y, He L · Frontiers in immunology · 2026-06-15

Randomized clinical trial

15. Exogenous Ketones Preserve Rate of Force Development in Young Adults.

Stoner JT, Buga A, Crabtree CD, Robinson BT, Decker DD, Sapper TN, Kackley ML, Kraemer WJ, Volek JS · Journal of strength and conditioning research · 2026-06-15

Clinical trial / intervention

16. Ketogenic Diet and β-Hydroxybutyrate Suppress Bladder Cancer Growth and Enhance Anti-PD-L1 Immunotherapy Efficacy.

Zeng Y, Gu G, Yang L, Fan B, Cui H, Yan L, Liu Z · Cancer science · 2026-06-11

Systematic review / meta-analysis

17. Effect of ketone supplementation, a low-carbohydrate diet and a ketogenic diet on heart failure measures and outcomes: a systematic review and meta-analysis.

Liao LP, Church LA, Melville H, Jayasinghe T, Choy C, Zeng A, Barrett N, Marschner S, Gan GCH, Thomas L, Zaman S · Heart (British Cardiac Society) · 2026-06-11

Randomized clinical trial

18. Determinants of Adherence to a Ketogenic Diet in Patients with Heart Failure with Reduced Ejection Fraction.

Liao LP, Murphy B, Gan GCH, Thomas L, Fontana L, McKinn S, Zaman S · Nutrients · 2026-06-09

Preclinical / mechanistic

19. Semaglutide-induced loss of skeletal muscle mass is blunted by co-administration of ketone esters.

Abuetabh Y, Schmidt MA, Naganuma M, Vaka R, El-Ghiaty MA, Braun S, Kwan EA, Zolondek MC, Sahid D, Khan L, Shandal RK, Trudeau AL, Li Y, Malik SO, Sun Q, Roth DK, Morales-Llamas DY, Levasseur JL, Ferdaoussi M, Fahlman RP, Dyck JR · JCI insight · 2026-06-09

Preclinical / mechanistic

20. Diet-Dependent Cognitive Benefits of Exogenous Ketone Body Precursor, (R,S)-1,3,-Butanediol, in a Mouse Model of Tauopathy.

Fulghum K, Hayir A, Ankeriasniemi R, Shaddy-Gouvion C, Vang CM, Salathe SF, Queathem ED, Hughey CC, Haeri M, Thyfault JP, Puchalska P, Crawford PA · bioRxiv : the preprint server for biology · 2026-06-08

Preclinical / mechanistic

21. Ketogenic Diet Modulates Depressive-Like Behavior via Gut Bacterial Metabolism of Tyrosine.

Zhang Y, Li X, Zhang X, Wang Y, Chen Z, Lin X, Zheng X, Hao H, Zhang X · FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026-05-14

Observational human study

22. Micronutrient intake in adults with drug-resistant epilepsy treated with the modified Atkins diet needs monitoring.

Kjendbakke I, Selmer KK, Nakken KO, Hofoss D, Iversen PO, Kverneland M · Frontiers in nutrition · 2026-05-07

Preclinical / mechanistic

23. Ketone Ester Attenuates Thoracic Aortic Aneurysm and Dissection by Suppressing Ferroptosis.

Shrestha S, Wu Y, Li J, Du X, Song P · Cells · 2026-05-01

Clinical trial / intervention

24. Metabolic and gut microbiota effects of ketogenic diet and exogenous ketone salts in a rat model of metabolic syndrome.

Pereira-Rodrigues A, Gonçalves A, Alves IN, Mendes CS, Silva C, Campos J, Sampaio-Maia B, Falcão-Pires I, Araujo R · European journal of nutrition · 2026-04-28

Preclinical / mechanistic

25. Ketogenic diet exacerbates DSS-induced colitis through a β-hydroxybutyrate-Thomasclavelia spiroformis-γδ17 T cell axis in mice.

Liu Y, Wu X, Chen L, Wang S, Xu J, Wang W, Yao X, Xie W, Zhong X, Li S, Li Y, Han L, Xie C, Chen L, Gonzalez FJ, Liu W · Nature communications · 2026-04-23

Clinical trial / intervention

26. Ketone ester supplementation in aged mice reduces activation of B cell subsets.

Adkisson-Floro A, Tiwari R, Nomura M, Riley RR, Kwok R, Sellegounder D, Khalid MM, Kasler HG, Newman JC, Verdin E · bioRxiv : the preprint server for biology · 2026-04-22

Systematic review / meta-analysis

27. The effect of exogenous ketone bodies on cognition across health and disease: a systematic review and meta-analysis.

Bonnechère B, Stephens EB, Boileau AC, Ducker M, Stubbs BJ · Frontiers in nutrition · 2026-04-15

Other

28. From Fuel to Flow: Translating the Beneficial Hemodynamic Effects of Exogenous Ketones in the ICU.

Elliott DM, Katz JN, Selvaraj S · JACC. Heart failure · 2026-04-03

Systematic review / meta-analysis

29. Exploring Non-pharmacological Hypertension Management: DASH, Paleolithic, and Ketogenic Diet Comparisons: A Systematic Review.

Wal P, Rath D, Verma N, Wal A, Bhukta P, Natania A, Ved A, Samathoti P, Gasmi A · Current hypertension reviews · 2026-03-26

Randomized clinical trial

30. The Effects of 31-Day Exogenous Ketone Consumption on Running Performance, Cognitive Function, Metabolism, Body Composition, Hemodynamics, and Mood in Recreational Runners: A Randomized-Control Trial.

Prins PJ, Buga A, Storoschuk K, Buxton JD, Jenkins AK, Eklund CS, Dacey VC, Belitz SE, Sullivan RJ, Gerhart HD, D'Agostino DP, Volek JS, Koutnik AP · Journal of the American Nutrition Association · 2026-03-03

Randomized clinical trial

31. Pharmacokinetic effects of a single dose nutritional ketone ester supplement on brain glucose and ketone metabolism in alcohol use disorder.

Li X, Young AJ, Shi Z, Byanyima J, Vesslee S, Reddy R, Pond T, Elliott M, Reddy R, Doot RK, van der Veen JW, Kranzler HR, Nanga RPR, Dubroff JG, Wiers CE · Psychiatry research. Neuroimaging · 2026-01-29

Other

32. Hemodynamic Effects of Oral Ketone Ester in Acutely Decompensated Heart Failure With Low Cardiac Output Syndrome.

Sramko M, Wohlfahrt P, Kissimon F, Svirlochova V, Franekova J, Kautzner J, Melenovsky V · JACC. Heart failure · 2026-01-07

Observational human study

33. L-Shaped Relationship Between Ketogenic Diet and High-Frequency Hearing Loss.

Zeng Q, Xiao Y, Sheng M, Liu B · The Laryngoscope · 2025-11-28

Other

34. Metabolic and Pharmacokinetic Profiling of a Ketone Ester by Background SGLT2 Inhibitor Therapy in HFrEF.

Selvaraj S, Kwee LC, Thompson EJ, He M, Hornik CP, Devore AD, Patel CB, Mentz RJ, Fudim M, Taylor L, Milosovic S, Hurdle M, Cade WT, Ilkayeva O, Muehlbauer MJ, Newgard CB, Kelly DP, Zamani P, Margulies KB, Shah SH · JACC. Basic to translational science · 2024-11-15

Randomized clinical trial

35. Multisystem impact of altering acid load of ingested exogenous ketone supplements at rest in young healthy adults.

McClure TS, Buxton JD, Egan B, Plank E, Isles M, Ault DL, Prins PJ, Koutnik AP · American journal of physiology. Regulatory, integrative and comparative physiology · 2024-12-31

Other

36. Neurohormonal and Renal Effects of 14-Day Oral Ketone Ester Treatment in Patients With Heart Failure With Reduced Ejection Fraction.

Berg-Hansen K, Gopalasingam N, Christensen KH, Svart M, Rittig N, Nielsen R, Lodberg K, Møller N, Wiggers H · Circulation. Heart failure · 2024-12-24

Clinical trial / intervention

37. Exogenous ketone bodies and the ketogenic diet as a treatment option for neurodevelopmental disorders.

Omori NE, Malys MK, Woo G, Mansor L · Frontiers in nutrition · 2024-12-19

Preclinical / mechanistic

38. Exogenous ketone therapy does not protect brain tissue after moderate-sized intracerebral hemorrhage despite signs of early neurological benefit.

Sander NH, Soni S, Wilkinson CM, Khiabani E, Dyck JRB, Colbourne F · PloS one · 2024-12-05

Clinical trial / intervention

39. Ketone ester-enriched diet ameliorates motor and dopamine release deficits in MitoPark mice.

Mahajan VR, Nadel JA, King MT, Pawlosky RJ, Davis MI, Veech RL, Lovinger DM, Salinas AG · The European journal of neuroscience · 2024-11-11

Randomized clinical trial

40. Impact of L-carnitine supplementation on gastric emptying and bowel function in pediatric ketogenic diet therapy: a clinical trial.

Nassar MF, Shata MO, Awadallah SM, Youssef MA, Ibrahim HE · Scientific reports · 2024-11-15

Randomized clinical trial

41. Exploring diet-induced ketosis with exogenous ketone supplementation as a potential intervention in post-traumatic stress disorder: a feasibility study.

Edwards MGP, Furuholmen-Jenssen T, Søegaard EGI, Thapa SB, Andersen JR · Frontiers in nutrition · 2024-10-31

Preclinical / mechanistic

42. Ketone Esters Partially and Selectively Rescue Mitochondrial Bioenergetics After Acute Cervical Spinal Cord Injury in Rats: A Time-Course.

Seira O, Park HD, Liu J, Poovathukaran M, Clarke K, Boushel R, Tetzlaff W · Cells · 2024-10-22

Randomized clinical trial

43. An Exogenous Ketone Ester Slows Tumor Progression in Murine Breast and Renal Cancer Models.

Ogbonna HN, Roberts Z, Godwin N, Muri P, Turbitt WJ, Swalley ZN, Dempsey FR, Stephens HR, Zhang J, Plaisance EP, Norian LA · Cancers · 2024-10-04

Randomized clinical trial

44. Acute effect of an exogenous ketone monoester supplement on appetite and food intake in adults with type 2 diabetes.

Oliveira B, Falkenhain K, Davy B, Davy K, Little J · Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme · 2024-06-03

Randomized clinical trial

45. Exploratory functional and quality of life outcomes with daily consumption of the ketone ester bis-octanoyl (R)-1,3-butanediol in healthy older adults: a randomized, parallel arm, double-blind, placebo-controlled study.

Stubbs BJ, Stephens EB, Senadheera C, Diaz SR, Peralta S, Alexander L, Silverman-Martin W, Kurtzig J, Fernando BA, Yurkovich JT, Garcia TY, Yukawa M, Morris J, Johnson JB, Newman JC · medRxiv : the preprint server for health sciences · 2024-09-18

Randomized clinical trial

46. Rationale and protocol for a safety, tolerability and feasibility randomized, parallel arm, double-blind, placebo-controlled, pilot study of a novel ketone ester targeting frailty via immunometabolic geroscience mechanisms.

Stubbs BJ, Alvarez Azañedo G, Peralta S, Diaz SR, Gray W, Alexander L, Silverman-Martin W, Garcia TY, Blonquist TM, Upadhyay V, Turnbaugh PJ, Johnson JB, Newman JC · PloS one · 2024-09-18

Review

47. Putative Role of Adenosine A1 Receptors in Exogenous Ketone Supplements-Evoked Anti-Epileptic Effect.

Kovács Z, Rauch E, D'Agostino DP, Ari C · International journal of molecular sciences · 2024-09-12

Clinical trial / intervention

48. A New Nomenclature for the Very Low-Calorie Ketogenic Diet (VLCKD): Very Low-Energy Ketogenic Therapy (VLEKT). Ketodiets and Nutraceuticals Expert Panels: "KetoNut", Italian Society of Nutraceuticals (SINut) and the Italian Association of Dietetics and Clinical Nutrition (ADI).

Barrea L, Caprio M, Grassi D, Cicero AFG, Bagnato C, Paolini B, Muscogiuri G · Current nutrition reports · 2024-07-23

Review

49. Exogenous ketone esters as a potential therapeutic for treatment of sarcopenic obesity.

Deemer SE, Roberts BM, Smith DL, Plaisance EP, Philp A · American journal of physiology. Cell physiology · 2024-05-20

Randomized clinical trial

50. Effect of Acute Nutritional Ketosis on Circulating Levels of Growth Differentiation Factor 15: Findings from a Cross-Over Randomised Controlled Trial.

Charles S, Liu Y, Bharmal SH, Kimita W, Petrov MS · Biomolecules · 2024-06-06

Preclinical / mechanistic

51. Exogenous Ketone Supplement Administration Abrogated Isoflurane-Anesthesia-Induced Increase in Blood Glucose Level in Female WAG/Rij Rats.

Rauch E, Ari C, D'Agostino DP, Kovács Z · Nutrients · 2024-05-14

Randomized clinical trial

52. Daily consumption of ketone ester, bis-octanoyl (R)-1,3-butanediol, is safe and tolerable in healthy older adults, a randomized, parallel arm, double-blind, placebo-controlled, pilot study.

Stubbs BJ, Stephens EB, Senadheera C, Peralta S, Roa-Diaz S, Alexander L, Silverman-Martin W, Garcia TY, Yukawa M, Morris J, Blonquist TM, Johnson JB, Newman JC · medRxiv : the preprint server for health sciences · 2024-05-05

Randomized clinical trial

53. A randomized open-label, observational study of the novel ketone ester, bis octanoyl (R)-1,3-butanediol, and its acute effect on ß-hydroxybutyrate and glucose concentrations in healthy older adults.

Stephens EB, Senadheera C, Roa-Diaz S, Peralta S, Alexander L, Silverman-Martin W, Yukawa M, Morris J, Johnson JB, Newman JC, Stubbs BJ · medRxiv : the preprint server for health sciences · 2024-04-18

Preclinical / mechanistic

54. Ketone ester supplementation of Atkins-type diet prolongs survival in an orthotopic xenograft model of glioblastoma.

Azari H, Poff A, D'Agostino D, Reynolds B · Anatomy & cell biology · 2024-01-09

Other

55. Is there evidence of a ketogenic effect of coconut oil? Commentary: Effect of the Mediterranean diet supplemented with nicotinamide riboside and pterostilbene and/or coconut oil on anthropometric variables in amyotrophic lateral sclerosis. A pilot study.

Norgren J, Kåreholt I, Sindi S · Frontiers in nutrition · 2024-01-08

Review

56. Beta-Hydroxybutyrate: A Supplemental Molecule for Various Diseases.

Shahtaghi NR, Soni B, Bakrey H, Bigdelitabar S, Jain SK · Current drug targets · 2024-03-28

Systematic review / meta-analysis

57. Effect of Acute and Chronic Ingestion of Exogenous Ketone Supplements on Blood Pressure: A Systematic Review and Meta-Analysis.

Marcotte-Chénard A, Tremblay R, Falkenhain K, Little JP, Riesco E · Journal of dietary supplements · 2023-12-25

Randomized clinical trial

58. The effect of acute and 14-day exogenous ketone supplementation on glycemic control in adults with type 2 diabetes: two randomized controlled trials.

Falkenhain K, Oliveira BF, Islam H, Neudorf H, Cen HH, Johnson JD, Madden K, Singer J, Walsh JJ, Little JP · American journal of physiology. Endocrinology and metabolism · 2023-11-22

Randomized clinical trial

59. The Effect of Novel Exogenous Ketone Supplements on Blood Beta-Hydroxybutyrate and Glucose.

Falkenhain K, Daraei A, Little JP · Journal of dietary supplements · 2023-02-27

Randomized clinical trial

60. Tolerability and Acceptability of an Exogenous Ketone Monoester and Ketone Monoester/Salt Formulation in Humans.

Bolyard ML, Graziano CM, Fontaine KR, Sayer RD, Fisher G, Plaisance EP · Nutrients · 2023-11-22

Randomized clinical trial

61. Rationale and protocol for a safety, tolerability and feasibility randomized, parallel group, double-blind, placebo-controlled, pilot study of a novel ketone ester targeting frailty via immunometabolic geroscience mechanisms.

Stubbs BJ, Alvarez-Azanedo G, Peralta S, Roa-Diaz S, Gray W, Alexander L, Silverman-Martin W, Garcia T, Blonquist TM, Upadhyay V, Turnbaugh PJ, Johnson JB, Newman JC · medRxiv : the preprint server for health sciences · 2023-10-26

Review

62. High-fat ketogenic diets and ketone monoester supplements differentially affect substrate metabolism during aerobic exercise.

Margolis LM, Pasiakos SM, Howard EE · American journal of physiology. Cell physiology · 2023-09-18

Randomized clinical trial

63. Beneficial Effects of Ketone Ester in Patients With Cardiogenic Shock: A Randomized, Controlled, Double-Blind Trial.

Berg-Hansen K, Christensen KH, Gopalasingam N, Nielsen R, Eiskjær H, Møller N, Birkelund T, Christensen S, Wiggers H · JACC. Heart failure · 2023-07-12

Other

64. Quantitative Determination of (R)-3-Hydroxybutyl (R)-3-Hydroxybutyrate (Ketone Ester) and Its Metabolites Beta-hydroxybutyrate, 1-3-Butanediol, and Acetoacetate in Human Plasma Using LC-MS.

Panse N, Halquist M, Gerk PM · AAPS PharmSciTech · 2023-09-12

Preclinical / mechanistic

65. Ketone ester administration improves glycemia in obese mice.

Tabatabaei Dakhili SA, Yang K, Locatelli CAA, Saed CT, Greenwell AA, Chan JSF, Chahade JJ, Scharff J, Al-Imarah S, Eaton F, Crawford PA, Gopal K, Mulvihill EE, Ussher JR · American journal of physiology. Cell physiology · 2023-08-14

Other

66. EPOtential target for endurance performance: the effect of exogenous ketone supplementation on circulating erythropoietin levels.

Robertson AA, Lynagh BM, Thompson KMA, McCarthy DG · The Journal of physiology · 2023-08-11

Randomized clinical trial

67. A Novel Powder Formulation of the Ketone Ester, Bis Hexanoyl (R)-1,3-Butanediol, Rapidly Increases Circulating ß-Hydroxybutyrate Concentrations in Healthy Adults.

Nieman KM, Anthony JC, Stubbs BJ · Journal of the American Nutrition Association · 2022-10-24

Preclinical / mechanistic

68. Ketone ester supplementation suppresses cardiac inflammation and improves cardiac energetics in a swine model of acute myocardial infarction.

Yurista SR, Eder RA, Welsh A, Jiang W, Chen S, Foster AN, Mauskapf A, Tang WHW, Hucker WJ, Coll-Font J, Rosenzweig A, Nguyen CT · Metabolism: clinical and experimental · 2023-06-01

Systematic review / meta-analysis

69. A systematic review and meta-regression of exogenous ketone infusion rates and resulting ketosis-A tool for clinicians and researchers.

Storoschuk KL, Wood TR, Stubbs BJ · Frontiers in physiology · 2023-06-28

Randomized clinical trial

70. Effects of Hypocaloric Low-Fat, Ketogenic, and Ketogenic and Ketone Supplement Diets on Aldosterone and Renin.

Belany P, Kackley ML, Zhao S, Kluwe B, Buga A, Crabtree CD, Nedungadi D, Kline D, Brock G, Simonetti OP, Volek JS, Joseph JJ · The Journal of clinical endocrinology and metabolism · 2022-08-11

Randomized clinical trial

71. Impact of one-day fasting, ketogenic diet or exogenous ketones on control of energy balance in healthy participants.

Hägele FA, Dörner R, Koop J, Lübken M, Seidel U, Rimbach G, Müller MJ, Bosy-Westphal A · Clinical nutrition ESPEN · 2023-04-10

Other

72. Ketone Esters and Their Effects on Carbohydrate Metabolism During Exercise.

Gonzalez JT · The Journal of nutrition · 2023-04-11

Randomized clinical trial

73. Metabolic markers of short and long-term exogenous DL-beta-hydroxybutyrate supplementation in episodic migraine patients: an exploratory analysis of a randomized-controlled-trial.

Putananickal N, Gross EC, Orsini AL, Schmidt S, Hafner P, Gocheva V, Nagy S, Henzi BC, Rubino D, Schädelin S, Sandor P, Fischer D · Frontiers in pharmacology · 2023-05-04

Randomized clinical trial

74. Fasting and diurnal blood ketonemia and glycemia responses to a six-week, energy-controlled ketogenic diet, supplemented with racemic R/S-BHB salts.

Buga A, Kackley ML, Crabtree CD, Bedell TN, Robinson BT, Stoner JT, Decker DD, Hyde PN, LaFountain RA, Brownlow ML, O'Connor A, Krishnan D, McElroy CA, Kraemer WJ, Volek JS · Clinical nutrition ESPEN · 2023-02-04

Randomized clinical trial

75. Oral ketone esters acutely improve myocardial contractility in post-hospitalized COVID-19 patients: A randomized placebo-controlled double-blind crossover study.

Wodschow HZ, Davidovski FS, Christensen J, Lassen MCH, Skaarup KG, Nygaard H, Møller N, Rungby J, Biering-Sørensen T, Rossing P, Jensen NJ, Laursen JC · Frontiers in nutrition · 2023-02-09

Review

76. Exogenous ketone supplementation: an emerging tool for physiologists with potential as a metabolic therapy.

Falkenhain K, Islam H, Little JP · Experimental physiology · 2022-12-19

Review

77. Exogenous Ketone Supplements in Athletic Contexts: Past, Present, and Future.

Evans M, McClure TS, Koutnik AP, Egan B · Sports medicine (Auckland, N.Z.) · 2022-10-10

Preclinical / mechanistic

78. Effects of an exogenous ketone ester using multi-omics in skeletal muscle of aging C57BL/6J male mice.

Roberts BM, Deemer SE, Smith DL, Mobley JA, Musi N, Plaisance EP · Frontiers in nutrition · 2022-11-15

Preclinical / mechanistic

79. Exogenous ketone ester administration attenuates systemic inflammation and reduces organ damage in a lipopolysaccharide model of sepsis.

Soni S, Martens MD, Takahara S, Silver HL, Maayah ZH, Ussher JR, Ferdaoussi M, Dyck JRB · Biochimica et biophysica acta. Molecular basis of disease · 2022-07-25

Randomized clinical trial

80. Ketone Ester Supplementation Improves Some Aspects of Cognitive Function during a Simulated Soccer Match after Induced Mental Fatigue.

Quinones MD, Lemon PWR · Nutrients · 2022-10-19

Other

81. Association of hypercalciuria with vitamin D supplementation in patients undergoing ketogenic dietary therapy.

Lee M, Lee HI, Song K, Choi HS, Suh J, Kim SH, Chae HW, Kang HC, Lee JS, Kim HD, Kim HS, Kwon A · Frontiers in nutrition · 2022-09-02

Other

82. [Ginkgo biloba Ketone Ester Tablets with different release rates prepared by fused deposition modeling 3D printing technology].

Li YY, Chen C, Wang HX, Xiang BB, Li Z · Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica · 2022-09-27

Clinical trial / intervention

83. Acute Ketone Salts-Caffeine-Taurine-Leucine Supplementation but not Ketone Salts-Taurine-Leucine, Improves Endurance Cycling Performance.

Quinones MD, Lemon PWR · International journal of sport nutrition and exercise metabolism · 2022-02-25

Clinical trial / intervention

84. Observation on the Efficacy of Ginkgo Ketone Ester Drop Pill in Improving Hypertension Combined with Carotid Atherosclerotic Plaque.

Zhang J, Ma Y · Emergency medicine international · 2022-06-30

Clinical trial / intervention

85. Efficacy and safety of ketone ester infusion to prevent muscle weakness in a mouse model of sepsis-induced critical illness.

Weckx R, Goossens C, Derde S, Pauwels L, Vander Perre S, Van den Berghe G, Langouche L · Scientific reports · 2022-06-22

Preclinical / mechanistic

86. The ketone ester, 3-hydroxybutyl-3-hydroxybutyrate, attenuates neurobehavioral deficits and improves neuropathology following controlled cortical impact in male rats.

Almeida-Suhett C, Namboodiri AM, Clarke K, Deuster PA · Nutritional neuroscience · 2020-12-09

Randomized clinical trial

87. No effect of oral ketone ester supplementation on exercise capacity in patients with McArdle disease and healthy controls: A randomized placebo-controlled cross-over study.

Løkken N, Storgaard JH, Revsbech KL, Voermans NC, Van Hall G, Vissing J, Ørngreen MC · Journal of inherited metabolic disease · 2022-02-20

Randomized clinical trial

88. Comparison of Exogenous Ketone Administration Versus Dietary Carbohydrate Restriction on Myocardial Glucose Suppression: A Crossover Clinical Trial.

Selvaraj S, Margulies KB, Dugyala S, Schubert E, Tierney A, Arany Z, Pryma DA, Shah SH, Rame JE, Kelly DP, Bravo PE · Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2021-10-21

Clinical trial / intervention

89. Evaluation of Acute Supplementation With the Ketone Ester (R)-3-Hydroxybutyl-(R)-3-Hydroxybutyrate (deltaG) in Healthy Volunteers by Cardiac and Skeletal Muscle 31P Magnetic Resonance Spectroscopy.

Cameron D, Soto-Mota A, Willis DR, Ellis J, Procter NEK, Greenwood R, Saunders N, Schulte RF, Vassiliou VS, Tyler DJ, Schmid AI, Rodgers CT, Malcolm PN, Clarke K, Frenneaux MP, Valkovič L · Frontiers in physiology · 2022-01-31

Randomized clinical trial

90. Ketone Ester Effects on Biomarkers of Brain Metabolism and Cognitive Performance in Cognitively Intact Adults ≥ 55 Years Old. A Study Protocol for a Double-Blinded Randomized Controlled Clinical Trial.

Avgerinos KI, Mullins RJ, Egan JM, Kapogiannis D · The journal of prevention of Alzheimer's disease · 2022-01-31

Randomized clinical trial

91. The Effects of 10-Day Exogenous Ketone Consumption on Repeated Time Trial Running Performances: A Randomized-Control Trial.

Jo E, Silva Ms SC, Auslander PhD AT, Arreglado Ms JP, Elam PhD ML, Osmond Ms AD, Steinberg Ms R, Wong Ms MWH · Journal of dietary supplements · 2020-10-28

Preclinical / mechanistic

92. Impact of ketogenic diet and ketone diester supplementation on body weight, blood glucose, and ketones in Sprague Dawley rats fed over two weeks.

Modica LCM, Flores-Felix K, Casachahua LJD, Asquith P, Tschiffely A, Ciarlone S, Ahlers ST · Food chemistry. Molecular sciences · 2021-06-10

Randomized clinical trial

93. Nutritional Formulation for Patients with Angelman Syndrome: A Randomized, Double-Blind, Placebo-Controlled Study of Exogenous Ketones.

Carson RP, Herber DL, Pan Z, Phibbs F, Key AP, Gouelle A, Ergish P, Armour EA, Patel S, Duis J · The Journal of nutrition · 2021-04-08

Preclinical / mechanistic

94. Chronic exogenous ketone supplementation blunts the decline of cardiac function in the failing heart.

Takahara S, Soni S, Phaterpekar K, Kim TT, Maayah ZH, Levasseur JL, Silver HL, Freed DH, Ferdaoussi M, Dyck JRB · ESC heart failure · 2021-10-06

Randomized clinical trial

95. A ketogenic supplement improves white matter energy supply and processing speed in mild cognitive impairment.

Roy M, Fortier M, Rheault F, Edde M, Croteau E, Castellano CA, Langlois F, St-Pierre V, Cuenoud B, Bocti C, Fulop T, Descoteaux M, Cunnane SC · Alzheimer's & dementia (New York, N. Y.) · 2021-11-17

Preclinical / mechanistic

96. Adenosine Receptors Modulate the Exogenous Ketogenic Supplement-Evoked Alleviating Effect on Lipopolysaccharide-Generated Increase in Absence Epileptic Activity in WAG/Rij Rats.

Brunner B, Ari C, D'Agostino DP, Kovács Z · Nutrients · 2021-11-15

Preclinical / mechanistic

97. Ketone Ester D-β-Hydroxybutyrate-(R)-1,3 Butanediol Prevents Decline in Cardiac Function in Type 2 Diabetic Mice.

Thai PN, Miller CV, King MT, Schaefer S, Veech RL, Chiamvimonvat N, Bers DM, Dedkova EN · Journal of the American Heart Association · 2021-09-29

Preclinical / mechanistic

98. Exogenous ketone ester delays CNS oxygen toxicity without impairing cognitive and motor performance in male Sprague-Dawley rats.

Stavitzski NM, Landon CS, Hinojo CM, Poff AM, Rogers CQ, D'Agostino DP, Dean JB · American journal of physiology. Regulatory, integrative and comparative physiology · 2021-06-16

Other

99. Exogenous Ketone Salt Supplementation and Whole-Body Cooling Do Not Improve Short-Term Physical Performance.

Clark D, Munten S, Herzig KH, Gagnon DD · Frontiers in nutrition · 2021-07-15

Case report / case series

100. Starvation Ketoacidosis Induced by Ketogenic Diet and Consumption of Ketone Supplement.

Malhi MS, Duerson F, Salabei JK, Okonoboh P · Cureus · 2021-06-20

Preclinical / mechanistic

101. Exogenous ketone salts inhibit superoxide production in the rat caudal solitary complex during exposure to normobaric and hyperbaric hyperoxia.

Hinojo CM, Ciarlone GE, D'Agostino DP, Dean JB · Journal of applied physiology (Bethesda, Md. : 1985) · 2021-03-04

Review

102. The Chemistry of the Ketogenic Diet: Updates and Opportunities in Organic Synthesis.

Williams MS, Turos E · International journal of molecular sciences · 2021-05-15

Other

103. Boron-catalyzed dehydrative allylation of 1,3-diketones and β-ketone esters with 1,3-diarylallyl alcohols in water.

Zhang GM, Zhang H, Wang B, Wang JY · RSC advances · 2021-05-10

Systematic review / meta-analysis

104. [Systematic evaluation on efficacy and safety of Gingko Ketone Ester Dropping Pills in treatment of angina pectoris and coronary heart disease].

Wang KY, Wang HC, Jin XY, Zhang MY, Li N, Pang WT, Wang H, Zhang JH · Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica · 2021-05-28

Randomized clinical trial

105. A dietary ketone ester mitigates histological outcomes of NAFLD and markers of fibrosis in high-fat diet fed mice.

Moore MP, Cunningham RP, Davis RAH, Deemer SE, Roberts BM, Plaisance EP, Rector RS · American journal of physiology. Gastrointestinal and liver physiology · 2021-01-27

Other

106. Acute Ketogenic Diet and Ketone Ester Supplementation Impairs Race Walk Performance.

Whitfield J, Burke LM, McKay AKA, Heikura IA, Hall R, Fensham N, Sharma AP · Medicine and science in sports and exercise · 2020-10-08

Observational human study

107. The Effects of a 6-Week Controlled, Hypocaloric Ketogenic Diet, With and Without Exogenous Ketone Salts, on Body Composition Responses.

Buga A, Kackley ML, Crabtree CD, Sapper TN, Mccabe L, Fell B, LaFountain RA, Hyde PN, Martini ER, Bowman J, Pan Y, Scandling D, Brownlow ML, O'Connor A, Simonetti OP, Kraemer WJ, Volek JS · Frontiers in nutrition · 2021-03-24

Other

108. Exogenous ketones in the healthy heart: the plot thickens.

Selvaraj S, Margulies KB · Cardiovascular research · 2020-10-19

Randomized clinical trial

109. Comparison of Ketogenic Diets with and without Ketone Salts versus a Low-Fat Diet: Liver Fat Responses in Overweight Adults.

Crabtree CD, Kackley ML, Buga A, Fell B, LaFountain RA, Hyde PN, Sapper TN, Kraemer WJ, Scandling D, Simonetti OP, Volek JS · Nutrients · 2021-03-17

Randomized clinical trial

110. The Effect of Exogenous Beta-Hydroxybutyrate Salt Supplementation on Metrics of Safety and Health in Adolescents.

Stefan M, Sharp M, Gheith R, Lowery R, Wilson J · Nutrients · 2021-03-05

Preclinical / mechanistic

111. Effects of ketogenic diet and ketone monoester supplement on acute alcohol withdrawal symptoms in male mice.

Bornebusch AB, Mason GF, Tonetto S, Damsgaard J, Gjedde A, Fink-Jensen A, Thomsen M · Psychopharmacology · 2021-01-07

Randomized clinical trial

112. Impact of Acutely Increased Endogenous- and Exogenous Ketone Bodies on FGF21 Levels in Humans.

Lauritzen ES, Svart MV, Voss T, Møller N, Bjerre M · Endocrine research · 2020-10-19

Preclinical / mechanistic

113. Age- and Sex-Dependent Modulation of Exogenous Ketone Supplement-Evoked Effects on Blood Glucose and Ketone Body Levels in Wistar Albino Glaxo Rijswijk Rats.

Kovács Z, Brunner B, D'Agostino DP, Ari C · Frontiers in neuroscience · 2021-01-11

Preclinical / mechanistic

114. Ingested Ketone Ester Leads to a Rapid Rise of Acetyl-CoA and Competes with Glucose Metabolism in the Brain of Non-Fasted Mice.

Suissa L, Kotchetkov P, Guigonis JM, Doche E, Osman O, Pourcher T, Lindenthal S · International journal of molecular sciences · 2021-01-07

Clinical trial / intervention

115. Exogenous Ketones as Therapeutic Signaling Molecules in High-Stress Occupations: Implications for Mitigating Oxidative Stress and Mitochondrial Dysfunction in Future Research.

Waldman HS, McAllister MJ · Nutrition and metabolic insights · 2020-12-10

Preclinical / mechanistic

116. Neuroprotective effects of a ketogenic diet in combination with exogenous ketone salts following acute spinal cord injury.

Tan BT, Jiang H, Moulson AJ, Wu XL, Wang WC, Liu J, Plunet WT, Tetzlaff W · Neural regeneration research · 2020-04-05

Randomized clinical trial

117. Dose response of a novel exogenous ketone supplement on physiological, perceptual and performance parameters.

Prins PJ, D'Agostino DP, Rogers CQ, Ault DL, Welton GL, Jones DW, Henson SR, Rothfuss TJ, Aiken KG, Hose JL, England EL, Atwell AD, Buxton JD, Koutnik AP · Nutrition & metabolism · 2020-09-29

Preclinical / mechanistic

118. The Effect of Exogenous Ketone Monoester Ingestion on Plasma BDNF During an Oral Glucose Tolerance Test.

Walsh JJ, Myette-Côté É, Little JP · Frontiers in physiology · 2020-09-09

Preclinical / mechanistic

119. Exogenous Ketone Supplements Improved Motor Performance in Preclinical Rodent Models.

Ari C, Murdun C, Goldhagen C, Koutnik AP, Bharwani SR, Diamond DM, Kindy M, D'Agostino DP, Kovacs Z · Nutrients · 2020-08-15

Preclinical / mechanistic

120. Exogenous Dietary Ketone Ester Decreases Body Weight and Adiposity in Mice Housed at Thermoneutrality.

Deemer SE, Davis RAH, Roberts BM, Smith DL, Koutnik AP, Poff AM, D'Agostino DP, Plaisance EP · Obesity (Silver Spring, Md.) · 2020-07-02

Other

121. Nutritional Ketosis with Ketogenic Diets or Exogenous Ketones: Features, Convergence, and Divergence.

Poff AM, Koutnik AP, Egan B · Current sports medicine reports · 2020-07-22

Randomized clinical trial

122. A Pre-Workout Supplement of Ketone Salts, Caffeine, and Amino Acids Improves High-Intensity Exercise Performance in Keto-Naïve and Keto-Adapted Individuals.

Kackley ML, Short JA, Hyde PN, LaFountain RA, Buga A, Miller VJ, Dickerson RM, Sapper TN, Barnhart EC, Krishnan D, McElroy CA, Maresh CM, Kraemer WJ, Volek JS · Journal of the American College of Nutrition · 2020-04-24

Other

123. Iron-Catalyzed Cleavage Reaction of Keto Acids with Aliphatic Aldehydes for the Synthesis of Ketones and Ketone Esters.

Zhou F, Li L, Lin K, Zhang F, Deng GJ, Gong H · Chemistry (Weinheim an der Bergstrasse, Germany) · 2020-03-03

Other

124. Exogenous Ketone Supplementation and Keto-Adaptation for Endurance Performance: Disentangling the Effects of Two Distinct Metabolic States.

Shaw DM, Merien F, Braakhuis A, Maunder E, Dulson DK · Sports medicine (Auckland, N.Z.) · 2019-12-11

Randomized clinical trial

125. Effects of an Exogenous Ketone Supplement on Five-Kilometer Running Performance.

Prins PJ, Koutnik AP, D'Agostino DP, Rogers CQ, Seibert JF, Breckenridge JA, Jackson DS, Ryan EJ, Buxton JD, Ault DL · Journal of human kinetics · 2020-03-31

Other

126. Exogenous Ketone Salts Do Not Improve Cognitive Performance During a Dual-Stress Challenge.

Waldman HS, Shepherd BD, Egan B, McAllister MJ · International journal of sport nutrition and exercise metabolism · 2019-11-21

Preclinical / mechanistic

127. A Dietary Ketone Ester Normalizes Abnormal Behavior in a Mouse Model of Alzheimer's Disease.

Pawlosky RJ, Kashiwaya Y, King MT, Veech RL · International journal of molecular sciences · 2020-02-04

Preclinical / mechanistic

128. Inhibition of adenosine A1 receptors abolished the nutritional ketosis-evoked delay in the onset of isoflurane-induced anesthesia in Wistar Albino Glaxo Rijswijk rats.

Kovács Z, Brunner B, D'Agostino DP, Ari C · BMC anesthesiology · 2020-01-30

Preclinical / mechanistic

129. Magnesium Supplementation did not affect the Antiseizure Property of Ketogenic Diet but Reduced Lipid Dysmetabolism.

Sanya EO, Adeyanju OA, Olarinoye JK, Bello H, Alaofin WA, Wahab KW, Soladoye AA · West African journal of medicine · 2020-02-08

Review

130. Potential Therapeutic Effects of Exogenous Ketone Supplementation for Type 2 Diabetes: A Review.

Walsh JJ, Myette-Côté É, Neudorf H, Little JP · Current pharmaceutical design · 2019-08-19

Other

131. Does ketone ester supplementation really blunt overreaching symptoms during endurance training overload?

Bellinger P · The Journal of physiology · 2019-08-16

Randomized clinical trial

132. Gastrointestinal Effects of Exogenous Ketone Drinks are Infrequent, Mild, and Vary According to Ketone Compound and Dose.

Stubbs BJ, Cox PJ, Kirk T, Evans RD, Clarke K · International journal of sport nutrition and exercise metabolism · 2019-01-15

Clinical trial / intervention

133. Dietary Supplementation With the Ketogenic Diet Metabolite Beta-Hydroxybutyrate Ameliorates Post-TBI Aggression in Young-Adult Male Drosophila.

Lee DC, Vali K, Baldwin SR, Divino JN, Feliciano JL, Fequiere JR, Fernandez MA, Frageau JC, Longo FK, Madhoun SS, Mingione V P, O'Toole TR, Ruiz MG, Tanner GR · Frontiers in neuroscience · 2019-10-30

Review

134. Ketone Administration for Seizure Disorders: History and Rationale for Ketone Esters and Metabolic Alternatives.

Poff AM, Rho JM, D'Agostino DP · Frontiers in neuroscience · 2019-10-15

Preclinical / mechanistic

135. Exogenous Ketones Lower Blood Glucose Level in Rested and Exercised Rodent Models.

Ari C, Murdun C, Koutnik AP, Goldhagen CR, Rogers C, Park C, Bharwani S, Diamond DM, Kindy MS, D'Agostino DP, Kovács Z · Nutrients · 2019-10-01

Randomized clinical trial

136. Effect of Synbiotic Supplementation in a Very-Low-Calorie Ketogenic Diet on Weight Loss Achievement and Gut Microbiota: A Randomized Controlled Pilot Study.

Gutiérrez-Repiso C, Hernández-García C, García-Almeida JM, Bellido D, Martín-Núñez GM, Sánchez-Alcoholado L, Alcaide-Torres J, Sajoux I, Tinahones FJ, Moreno-Indias I · Molecular nutrition & food research · 2019-08-29

Other

137. Can ketone esters support an appetite to perform and recover?

Cervone DT, Hucik B, Wickham KA · The Journal of physiology · 2019-08-18

Other

138. Ketone ester supplementation in endurance athletes: a miracle drink or 'spin'?

Korevaar DA, Cohen JF, McInnes MDF · The Journal of physiology · 2019-08-16

Randomized clinical trial

139. Ketone ester supplementation blunts overreaching symptoms during endurance training overload.

Poffé C, Ramaekers M, Van Thienen R, Hespel P · The Journal of physiology · 2019-05-22

Clinical trial / intervention

140. Therapeutic Potential of Exogenous Ketone Supplement Induced Ketosis in the Treatment of Psychiatric Disorders: Review of Current Literature.

Kovács Z, D'Agostino DP, Diamond D, Kindy MS, Rogers C, Ari C · Frontiers in psychiatry · 2019-05-23

Preclinical / mechanistic

141. Concentration-Dependent Effects of a Dietary Ketone Ester on Components of Energy Balance in Mice.

Deemer SE, Davis RAH, Gower BA, Koutnik AP, Poff AM, Dickinson SL, Allison DB, D'Agostino DP, Plaisance EP · Frontiers in nutrition · 2019-05-01

Randomized clinical trial

142. Efficacy and safety of exogenous ketone bodies for preventive treatment of migraine: A study protocol for a single-centred, randomised, placebo-controlled, double-blind crossover trial.

Gross E, Putananickal N, Orsini AL, Schmidt S, Vogt DR, Cichon S, Sandor P, Fischer D · Trials · 2019-01-17

Preclinical / mechanistic

143. Elevated Plus Maze Test Combined with Video Tracking Software to Investigate the Anxiolytic Effect of Exogenous Ketogenic Supplements.

Ari C, D'Agostino DP, Diamond DM, Kindy M, Park C, Kovács Z · Journal of visualized experiments : JoVE · 2019-01-07

Preclinical / mechanistic

144. Delaying latency to hyperbaric oxygen-induced CNS oxygen toxicity seizures by combinations of exogenous ketone supplements.

Ari C, Koutnik AP, DeBlasi J, Landon C, Rogers CQ, Vallas J, Bharwani S, Puchowicz M, Bederman I, Diamond DM, Kindy MS, Dean JB, D Agostino DP · Physiological reports · 2018-10-07

Preclinical / mechanistic

145. Preventive effects of ketone ester BD-AcAc2 on central nervous system oxygen toxicity and concomitant acute lung injury.

Yi H, Yu S, Zhang Y, Li R, Zhang D, Zhang D, Xu W · Diving and hyperbaric medicine · 2018-08-09

Randomized clinical trial

146. Two-Week Exclusive Supplementation of Modified Ketogenic Nutrition Drink Reserves Lean Body Mass and Improves Blood Lipid Profile in Obese Adults: A Randomized Clinical Trial.

Choi HR, Kim J, Lim H, Park YK · Nutrients · 2018-12-03

Randomized clinical trial

147. Intermittent Running and Cognitive Performance after Ketone Ester Ingestion.

Evans M, Egan B · Medicine and science in sports and exercise · 2018-06-27

Preclinical / mechanistic

148. Nutritional ketosis delays the onset of isoflurane induced anesthesia.

Ari C, Kovács Z, Murdun C, Koutnik AP, Goldhagen CR, Rogers C, Diamond D, D'Agostino DP · BMC anesthesiology · 2018-07-18

Randomized clinical trial

149. Exogenous ketone salts do not improve cognitive responses after a high-intensity exercise protocol in healthy college-aged males.

Waldman HS, Basham SA, Price FG, Smith JW, Chander H, Knight AC, Krings BM, McAllister MJ · Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme · 2018-02-16

Other

150. The glucose-lowering effects of exogenous ketones: is there therapeutic potential?

Egan B · The Journal of physiology · 2018-03-24

Preclinical / mechanistic

151. Anxiolytic Effect of Exogenous Ketone Supplementation Is Abolished by Adenosine A1 Receptor Inhibition in Wistar Albino Glaxo/Rijswijk Rats.

Kovács Z, D'Agostino DP, Ari C · Frontiers in behavioral neuroscience · 2018-02-22

Randomized clinical trial

152. A Ketone Ester Drink Lowers Human Ghrelin and Appetite.

Stubbs BJ, Cox PJ, Evans RD, Cyranka M, Clarke K, de Wet H · Obesity (Silver Spring, Md.) · 2017-11-06

Review

153. Exogenous Ketone Bodies as Promising Neuroprotective Agents for Developmental Brain Injury.

Wood TR, Stubbs BJ, Juul SE · Developmental neuroscience · 2019-05-14

Randomized clinical trial

154. On the Metabolism of Exogenous Ketones in Humans.

Stubbs BJ, Cox PJ, Evans RD, Santer P, Miller JJ, Faull OK, Magor-Elliott S, Hiyama S, Stirling M, Clarke K · Frontiers in physiology · 2017-10-30

Preclinical / mechanistic

155. The 1-Week and 8-Month Effects of a Ketogenic Diet or Ketone Salt Supplementation on Multi-Organ Markers of Oxidative Stress and Mitochondrial Function in Rats.

Kephart WC, Mumford PW, Mao X, Romero MA, Hyatt HW, Zhang Y, Mobley CB, Quindry JC, Young KC, Beck DT, Martin JS, McCullough DJ, D'Agostino DP, Lowery RP, Wilson JM, Kavazis AN, Roberts MD · Nutrients · 2017-09-15

Randomized clinical trial

156. A Ketone Ester Drink Increases Postexercise Muscle Glycogen Synthesis in Humans.

Holdsworth DA, Cox PJ, Kirk T, Stradling H, Impey SG, Clarke K · Medicine and science in sports and exercise · 2017-04-12

Randomized clinical trial

157. Intake of a Ketone Ester Drink during Recovery from Exercise Promotes mTORC1 Signaling but Not Glycogen Resynthesis in Human Muscle.

Vandoorne T, De Smet S, Ramaekers M, Van Thienen R, De Bock K, Clarke K, Hespel P · Frontiers in physiology · 2017-05-23

Preclinical / mechanistic

158. Effects of a dietary ketone ester on hippocampal glycolytic and tricarboxylic acid cycle intermediates and amino acids in a 3xTgAD mouse model of Alzheimer's disease.

Pawlosky RJ, Kemper MF, Kashiwaya Y, King MT, Mattson MP, Veech RL · Journal of neurochemistry · 2017-03-15

Other

159. Mg(OMe)2 promoted allylic isomerization of γ-hydroxy-α,β-alkenoic esters to synthesize γ-ketone esters.

Lai L, Li AN, Zhou J, Guo Y, Lin L, Chen W, Wang R · Organic & biomolecular chemistry · 2017-02-22

Preclinical / mechanistic

160. Corrigendum: Exogenous Ketone Supplements Reduce Anxiety-Related Behavior in Sprague-Dawley and Wistar Albino Glaxo/Rijswijk Rats.

Ari C, Kovács Z, Juhasz G, Murdun C, Goldhagen CR, Koutnik AP, Poff AM, Kesl SL, D'Agostino DP · Frontiers in molecular neuroscience · 2017-02-13

Preclinical / mechanistic

161. Ketone ester supplementation attenuates seizure activity, and improves behavior and hippocampal synaptic plasticity in an Angelman syndrome mouse model.

Ciarlone SL, Grieco JC, D'Agostino DP, Weeber EJ · Neurobiology of disease · 2016-08-18

Randomized clinical trial

162. Effect of DHA supplementation in a very low-calorie ketogenic diet in the treatment of obesity: a randomized clinical trial.

de Luis D, Domingo JC, Izaola O, Casanueva FF, Bellido D, Sajoux I · Endocrine · 2016-04-27

Randomized clinical trial

163. Very-low-calorie ketogenic diet with aminoacid supplement versus very low restricted-calorie diet for preserving muscle mass during weight loss: a pilot double-blind study.

Merra G, Miranda R, Barrucco S, Gualtieri P, Mazza M, Moriconi E, Marchetti M, Chang TF, De Lorenzo A, Di Renzo L · European review for medical and pharmacological sciences · 2016-07-08

Preclinical / mechanistic

164. Effects of exogenous ketone supplementation on blood ketone, glucose, triglyceride, and lipoprotein levels in Sprague-Dawley rats.

Kesl SL, Poff AM, Ward NP, Fiorelli TN, Ari C, Van Putten AJ, Sherwood JW, Arnold P, D'Agostino DP · Nutrition & metabolism · 2016-02-04

Case report / case series

165. Effects of Pre-surgical Vitamin D Supplementation and Ketogenic Diet in a Patient with Recurrent Breast Cancer.

Branca JJ, Pacini S, Ruggiero M · Anticancer research · 2015-09-27

Preclinical / mechanistic

166. Anticonvulsant properties of an oral ketone ester in a pentylenetetrazole-model of seizure.

Viggiano A, Pilla R, Arnold P, Monda M, D'Agostino D, Coppola G · Brain research · 2015-05-27

Preclinical / mechanistic

167. Non-Toxic Metabolic Management of Metastatic Cancer in VM Mice: Novel Combination of Ketogenic Diet, Ketone Supplementation, and Hyperbaric Oxygen Therapy.

Poff AM, Ward N, Seyfried TN, Arnold P, D'Agostino DP · PloS one · 2015-06-10

Case report / case series

168. A new way to produce hyperketonemia: use of ketone ester in a case of Alzheimer's disease.

Newport MT, VanItallie TB, Kashiwaya Y, King MT, Veech RL · Alzheimer's & dementia : the journal of the Alzheimer's Association · 2014-10-07

Review

170. Ketone body therapy: from the ketogenic diet to the oral administration of ketone ester.

Hashim SA, VanItallie TB · Journal of lipid research · 2014-03-05

Review

171. Ketone esters increase brown fat in mice and overcome insulin resistance in other tissues in the rat.

Veech RL · Annals of the New York Academy of Sciences · 2013-08-02

Preclinical / mechanistic

172. Therapeutic ketosis with ketone ester delays central nervous system oxygen toxicity seizures in rats.

D'Agostino DP, Pilla R, Held HE, Landon CS, Puchowicz M, Brunengraber H, Ari C, Arnold P, Dean JB · American journal of physiology. Regulatory, integrative and comparative physiology · 2013-04-03

Preclinical / mechanistic

173. Triheptanoin supplementation to ketogenic diet curbs cognitive impairment in APP/PS1 mice used as a model of familial Alzheimer's disease.

Aso E, Semakova J, Joda L, Semak V, Halbaut L, Calpena A, Escolano C, Perales JC, Ferrer I · Current Alzheimer research · 2012-04-04

Review

174. Carnitine, nutritional supplementation and discontinuation of ketogenic diet therapies.

Neal EG, Zupec-Kania B, Pfeifer HH · Epilepsy research · 2012-06-15

Preclinical / mechanistic

175. Mitochondrial biogenesis and increased uncoupling protein 1 in brown adipose tissue of mice fed a ketone ester diet.

Srivastava S, Kashiwaya Y, King MT, Baxa U, Tam J, Niu G, Chen X, Clarke K, Veech RL · FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2012-02-23

Other

176. Reduction of exogenous ketones depends upon NADPH generated photosynthetically in cells of the cyanobacterium Synechococcus PCC 7942.

Yamanaka R, Nakamura K, Murakami A · AMB Express · 2011-09-01

Randomized clinical trial

177. Keto analogue and amino acid supplementation affects the ammonaemia response during exercise under ketogenic conditions.

Prado ES, de Rezende Neto JM, de Almeida RD, Dória de Melo MG, Cameron LC · The British journal of nutrition · 2011-02-16

Observational human study

178. Prospective study of the modified atkins diet in combination with a ketogenic liquid supplement during the initial month.

Kossoff EH, Dorward JL, Turner Z, Pyzik PL · Journal of child neurology · 2010-09-10

Preclinical / mechanistic

179. A ketone ester diet increases brain malonyl-CoA and Uncoupling proteins 4 and 5 while decreasing food intake in the normal Wistar Rat.

Kashiwaya Y, Pawlosky R, Markis W, King MT, Bergman C, Srivastava S, Murray A, Clarke K, Veech RL · The Journal of biological chemistry · 2010-06-07

Review

180. Long-term management of the ketogenic diet: seizure monitoring, nutrition, and supplementation.

Zupec-Kania B, Zupanc ML · Epilepsia · 2008-12-17

Other

181. Modification of haloalkane-induced hepatotoxicity by exogenous ketones and metabolic ketosis.

Hewitt WR, Miyajima H, Côté MG, Plaa GL · Federation proceedings · 1980-11-01

Preclinical / mechanistic

182. Ketogenic diet and ketone salts differentially improve cardiometabolic complications in an HFpEF rat model.

Gonçalves A, Alves IN, Mendes C, Miranda D, Conceição G, Almeida-Coelho J, Martins D, Miranda I, Rodrigues A, Silva C, Oliveira SM, Sereno J, Ferreira MJ, Dischinger U, Girão H, Leite-Moreira AF, Sequeira V, Falcão-Pires I · The Journal of physiology · 2025-04-03

Randomized clinical trial

183. Should Exogenous Ketone Body Supplementation Be Considered in Patients Hospitalized for Acute Heart Failure? Rationale and Design of the KETO-AHF Trial.

Berg-Hansen K, Tinggaard AB, Nielsen R, Jensen TH, Gopalasingam N, Larsen AH, Møller N, Böttcher M, Hollingdal M, Poulsen MK, Antonsen L, Kondo T, Jhund PS, Borlaug BA, Mebazaa A, Møller JE, Vraa S, Grand J, Hove JD, Wolsk E, Schou M, Wiggers H · Journal of cardiac failure · 2025-08-09

Other

184. The Role of Carnitine Monitoring and Supplementation in Children With Epilepsy on a Ketogenic Diet.

Vail E, Turner Z, Kossoff EH · Journal of child neurology · 2025-07-23

Clinical trial / intervention

185. Exogenous ketone monoester supplementation: a potential alternative strategy to mitigate altitude sickness?

Thiessen JS, Miners NI, McCarthy DG, Millar PJ, Bommarito JC, Swenson ER, Walsh JJ, Tymko MM · European journal of applied physiology · 2025-12-04

Randomized clinical trial

186. Crossover Trial of Exogenous Ketones on Cardiometabolic Endpoints in Heart Failure With Preserved Ejection Fraction.

Selvaraj S, Karaj A, Chirinos JA, Denney N, Grosso G, Fernando M, Chambers K, Demastus C, Reddy R, Langham M, Kumar D, Maynard H, Pourmussa B, Prenner SB, Cohen JB, Ischiropoulos H, Rickels MR, Poole DC, Church DD, Wolfe RR, Kelly DP, Putt M, Margulies KB, Zamani P · JACC. Heart failure · 2025-03-29

Randomized clinical trial

187. Effect of Exogenous Ketones as an Adjunct to Low-Calorie Diet on Metabolic Markers.

Roeth EJ, Parker G, Cooper-Leavitt EF, Beus CG, Braithwaite CR, Morris MD, Reynolds AP, Evans EP, Radford JH, Davis FD, Reynolds PR, Parrish RR, Bikman BT · Nutrients · 2025-11-16

Preclinical / mechanistic

188. Ketone ester supplementation protects from experimental colitis via improved goblet cell differentiation and function.

Rohwer N, Sander A, Ocvirk S, Wiebel M, Kühl AA, Schebb NH, Grune T, Weylandt KH · European journal of nutrition · 2025-11-12

Randomized clinical trial

189. Potential therapeutic benefit of exogenous ketone ester administration in delirium: a narrative review.

Smith R, Harrison F, Bastarache J, Williams Roberson S, Zaganjor E, Pandharipande P, Rice T, Ely W · Critical care (London, England) · 2025-10-07

Preclinical / mechanistic

190. Divergent Hepatic Outcomes of Chronic Ketone Supplementation: Ketone Salts Preserve Liver Health While Ketone Esters and Precursors Drive Inflammation and Steatosis.

Ari C, D'Agostino DP · Pharmaceuticals (Basel, Switzerland) · 2025-09-25

Clinical trial / intervention

191. Effectiveness of Medical Nutrition Therapy in the Management of Patients with Obesity and Endometriosis: from the Mediterranean Diet To the Ketogenic Diet, Through Supplementation. The Role of the Nutritionist in Clinical Management.

Barrea L, Verde L, Annunziata G, Chedraui P, Petraglia F, Cucalón G, Camajani E, Caprio M, Gorini S, Iorio GG, Di Girolamo R, Carbone L, Chapela S, Frias-Toral E, Muscogiuri G · Current obesity reports · 2025-09-08

Other

192. Practical challenges and ethical considerations in treating early-onset MADD with exogenous ketones.

LoPiccolo MK, Van Hove JLK · Molecular genetics and metabolism · 2025-08-27

Other

193. Synthesis and Antifungal Activity of Raspberry Ketone Ester Derivatives as Potential Fungicides.

Shu L, Wei Z, Wang Y, Li Y, Zhao Y, Tian Y, Qian L, Chen G, Liu S, Huang X, Hao N, Che Z · Chemistry & biodiversity · 2025-04-26

Randomized clinical trial

194. Ketone ester ingestion increases exogenous carbohydrate storage and lowers glycemia during post-exercise recovery: a randomised crossover trial.

Clarke L, Russell SL, Spellanzon B, Maher JL, Betts JA, Gonzalez JT · European journal of nutrition · 2025-08-12

Preclinical / mechanistic

195. Exogenous Ketone Supplementation Enhances the Anti-Epileptic Effect of Levetiracetam in Wistar Albino Glaxo/Rijswijk Rats.

Rauch E, Ari C, D'Agostino DP, Kovács Z · Nutrients · 2025-05-20

Randomized clinical trial

196. Effectiveness of Exogenous Ketone Salts in Enhancing Circulating Acetoacetate Levels-A Pilot Study in Healthy Adults.

Holland-Winkler AM, Moore AR, Bederman I · Nutrients · 2025-05-14

Systematic review / meta-analysis

197. Symptoms during initiation of a ketogenic diet: a scoping review of occurrence rates, mechanisms and relief strategies.

Skartun O, Smith CR, Laupsa-Borge J, Dankel SN · Frontiers in nutrition · 2025-03-26

Preclinical / mechanistic

198. Characterizing the Hepatic Metabolic Pathway of Ketone Ester and Subsequent Metabolites Using Human and Rat Liver Fractions.

Panse N, Gerk PM · The AAPS journal · 2025-03-14

Randomized clinical trial

199. Effects of Ketone Ester Supplementation on Cognition and Appetite in Individuals with and Without Metabolic syndrome: A Randomized Trial.

Graybeal AJ, Aultman RS, Brandner CF, Vallecillo-Bustos A, Compton AT, Swafford SH, Newsome TA, Stavres J · Journal of dietary supplements · 2025-03-04

Exercise Science

Exercise & Performance Recent peer-reviewed literature

Source-audited selection from the connected PDF archive. Systematic reviews/meta-analyses and recent human evidence are prioritized when available; sparse areas are explicitly kept sparse.

Recent review/study · 2026

1. Effects of Low-Carbohydrate and Ketogenic Diets on Anaerobic Performance in Competitive Athletes

Original publication title: Effects of Low-Carbohydrate and Ketogenic Diets on Anaerobic Performance in Competitive Athletes

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Recent review/study · 2026

2. Effects of Low-Carbohydrate and Ketogenic Diets on Aerobic Performance in Trained Athletes

Original publication title: Effects of Low-Carbohydrate and Ketogenic Diets on Aerobic Performance in Trained Athletes

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Systematic review & meta-analysis · 2025

3. Effects of Ketogenic Diet on Muscle Mass, Strength, Aerobic Metabolic Capacity, and Endurance in Adults: A Systematic Review and Meta-Analysis

Original publication title: Effects of Ketogenic Diet on Muscle Mass, Strength, Aerobic Metabolic Capacity, and Endurance in Adults: A Systematic Review and Meta-Analysis

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Recent review · 2025

4. The Science of Ketogenic Supplements for Athletes

Original publication title: The Science of Ketogenic Supplements for Athletes

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Human performance study · 2025

5. Strategic Carbohydrate Feeding Improves Performance in Ketogenic Athletes

Original publication title: Strategic Carbohydrate Feeding Improves Performance in Ketogenic Athletes

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Systematic review · 2025

6. A Systematic Review of the Effects of Low-Carbohydrate Diet on Athletic Physical Performance

Original publication title: A Systematic Review of the Effects of Low-Carbohydrate Diet on Athletic Physical Performance

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Systematic review & meta-analysis

7. Effects of the Ketogenic Diet on Strength Performance in Trained Men and Women: A Systematic Review and Meta-Analysis

Original publication title: Effects of the Ketogenic Diet on Strength Performance in Trained Men and Women: A Systematic Review and Meta-Analysis

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Position stand

8. International Society of Sports Nutrition Position Stand: Ketogenic Diets

Original publication title: International Society of Sports Nutrition Position Stand: Ketogenic Diets

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Human / clinical or translational evidence

9. Does a Low-Carbohydrate Diet Impede Endurance Sports Performance? The Case Against

Original publication title: Does a Low-Carbohydrate Diet Impede Endurance Sports Performance? The Case Against

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Human / clinical or translational evidence

10. Does a Low-Carbohydrate Diet Impede Endurance Sports Performance? The Case For

Original publication title: Does a Low-Carbohydrate Diet Impede Endurance Sports Performance? The Case For

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Human / clinical or translational evidence

11. The Influence of Physical Exercise, Ketogenic Diet, and Time-Restricted Eating on De Novo Lipogenesis

Original publication title: The Influence of Physical Exercise, Ketogenic Diet, and Time-Restricted Eating on De Novo Lipogenesis

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Human / clinical or translational evidence

12. Impact of the Ketogenic Diet on Body Fat in Athletes

Original publication title: Impact of the Ketogenic Diet on Body Fat in Athletes

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Clinical trial · 2024

13. The Effect of the Ketogenic Diet on Resistance Training Load Management: A Repeated-Measures Clinical Trial in Trained Participants

Original publication title: The Effect of the Ketogenic Diet on Resistance Training Load Management: A Repeated-Measures Clinical Trial in Trained Participants

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Human intervention study · 2023

14. VLCKD Combined with Physical Interval Training

Original publication title: VLCKD Combined with Physical Interval Training

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Review · 2023

15. Exogenous Ketone Supplementation and Ketogenic Diets for Exercise: Effects on Skeletal Muscle Metabolism

Original publication title: Exogenous Ketone Supplementation and Ketogenic Diets for Exercise: Effects on Skeletal Muscle Metabolism

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Human athlete study · 2023

16. Adherence to a Ketogenic Low-Carbohydrate, High-Fat Diet Is Associated With Diminished Training Quality in Elite Racewalkers

Original publication title: Adherence to a Ketogenic Low-Carbohydrate, High-Fat Diet Is Associated With Diminished Training Quality in Elite Racewalkers

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Human intervention study

17. Ketogenic Diet Combined with Moderate Aerobic Exercise

Original publication title: Ketogenic Diet Combined with Moderate Aerobic Exercise

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Human training study

18. Effects of the Ketogenic Diet on Muscle Hypertrophy in Resistance-Trained Men and Women

Original publication title: Effects of the Ketogenic Diet on Muscle Hypertrophy in Resistance-Trained Men and Women

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Review

19. Ketogenic Diet and Skeletal Muscle Hypertrophy: A Frenemy Relationship

Original publication title: Ketogenic Diet and Skeletal Muscle Hypertrophy: A Frenemy Relationship

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Human exercise study

20. Effects of 30 Days of Ketogenic Diet on Exercise Performance

Original publication title: Effects of 30 Days of Ketogenic Diet on Exercise Performance

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Controlled case study

21. Keto Menu–Effect of Ketogenic Menu and Intermittent Fasting on the Biochemical Markers and Body Composition in a Physically Active Man—A Controlled Case Study

Original publication title: Keto Menu–Effect of Ketogenic Menu and Intermittent Fasting on the Biochemical Markers and Body Composition in a Physically Active Man—A Controlled Case Study

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Randomized clinical trial

22. Supplementation With Ketogenic Precursors Enhances Virtual Reality Shooting Performance During Sleep Restriction: A Randomized, Placebo-Controlled, Crossover Trial.

Buga A, Stoner JT, Sapper TN, Crabtree CD, Decker DD, Robinson BT, Kackley ML, McClure T, Chebbi A, Stalter H, Dawson L, Whiteman A, Spencer M, Lane L, Hayes SM, Mindel J, Kraemer WJ, Volek JS · Military medicine · 2026-09-17

Review

23. Sparing Muscle While Losing Fat: A Narrative Review of Ketogenic Diets and Lean Mass Preservation During Weight Loss.

Caturano A, Mocini E, Titi L, Leva F, Cannavaro D, Tarsitano MG, Conte C · Nutrients · 2026-09-07

Other

24. Ketone Ester Intake Did Not Improve Performance, Neither Cognitive Function or Sleep, During an 8-Day Simulated Cycling Race.

Engelbrecht L, Lauriks W, Robberechts R, Stalmans M, Ramaekers M, Terblanche E, Koppo K, Poffé C · Medicine and science in sports and exercise · 2026-08-27

Other

25. [Ketogenic diet reintroduction in an adult patient with glucose transporter type 1 deficiency syndrome].

Kusakabe S, Osakada Y, Morihara R, Dohi Y, Shimono K, Ishiura H · Rinsho shinkeigaku = Clinical neurology · 2026-08-07

Clinical trial / intervention

26. The ketogenic diet ameliorates behavioral abnormalities in a PTZ-induced zebrafish larvae model via modulating neurotransmitter balance.

Yang X, Lin J, Zhang Q, Xia Y, Zhou S, Wang Y, Li Q, Yu L · IBRO neuroscience reports · 2026-08-04

Preclinical / mechanistic

27. Ckmm-Cre transgenic mice maintain phenotypic and cardiac mitochondrial homeostasis during ketogenic feeding.

Dogan SA · Molecular and cellular biochemistry · 2026-07-29

Randomized clinical trial

28. Acute 1,3-Butanediol Co-Ingestion with Carbohydrate Does Not Improve Endurance Performance in Chronically Ketogenic Male Athletes.

Carpenter M, Brouner J, Spendiff O · Nutrients · 2026-07-22

Other

29. Integrated UPLC-MS/MS with interpretable artificial intelligence-enhanced Raman and near-infrared spectroscopy for multi-objective monitoring of ginkgo ketone ester tablets column purification.

Zhou Q, Jiang M, Wang D, Wang J, Tao Y · Journal of pharmaceutical and biomedical analysis · 2026-07-17

Clinical trial / intervention

30. Predicting the efficacy of classic ketogenic diet therapy in children with refractory epilepsy using dynamic changes in the glucose-ketone index (GKI).

Li J, Wang T, Yu L, Ni Y, Li Y, Zhang Y, Zhou S, Wang Y · Seizure · 2026-07-12

Clinical trial / intervention

31. Intensive multimodal ketogenic metabolic therapy in glioblastoma: A clinical trial.

Phillips MCL, Thotathil Z, Haji Mohd Yasin NAB, de Groot C, Tan A, Kuper-Hommel M, Creagh LA, Ji E, Naidoo N, van Essen M, Ziad F, Moon BG, Frampton C, Jameson MB · Neuro-oncology advances · 2026-06-29

Observational human study

32. Early Electroencephalographic Changes After Ketogenic Diet Initiation Are Associated With Clinical Response in Pediatric Drug-Resistant Epilepsy.

Yavuz M, Unalp A, Gulagız F, Guzin Y, Yılmaz U · Seizure · 2026-06-10

Systematic review / meta-analysis

33. Effects of Low-Carbohydrate and Ketogenic Diets on Anaerobic Performance in Competitive Athletes: A Systematic Review and Meta-Analysis.

Gawelczyk M, Chycki J, Maszczyk A, Zając A · Nutrients · 2026-05-16

Systematic review / meta-analysis

34. Effects of the Ketogenic Diet on Gonadal Hormones: A Systematic Review.

Lima M, Fabe J, Grigolon RB, Ceolin G, Palma N, Gerchman F, Brietzke E, Gomes FA · Nutrition reviews · 2026-05-12

Clinical trial / intervention

35. Ketogenic Diets and Low-Density Lipoprotein Cholesterol in Adults With Normal Weight: An Emerging Clinical Challenge.

DiMattia ZS, Petersen KS · Journal of the American Heart Association · 2026-04-28

Observational human study

36. Long term outcomes of children started on the Ketogenic diet for pediatric super refractory status epilepticus- 15 years single center experience.

Hommady R, Lowe H, Dickson J, Owusu K, Kobayashi J, Hahn C, Zak M, Hopkins S, Jain P, McKinnon N, Donner E, Sharma S · Seizure · 2026-04-16

Randomized clinical trial

37. From clinical practice to mechanistic insights in ketogenic diets for epilepsy.

Figueroa AG, Joshi CN, Patel MN · The Lancet. Neurology · 2026-03-11

Preclinical / mechanistic

38. Ketogenic diet causes bone loss in growing and adult mice and reduces the skeletal response to exercise.

Osipov B, Robison L, Hanel J, Orr SV, Lin YY, Buxton A, Rahmati M, Tseng MC, Renato MR, Shenoy R, Bhat AS, Saiz A, Ferguson VL, Loots GG, Christiansen BA · Bone · 2026-03-09

Randomized clinical trial

39. The Effects of 31-Day Exogenous Ketone Consumption on Running Performance, Cognitive Function, Metabolism, Body Composition, Hemodynamics, and Mood in Recreational Runners: A Randomized-Control Trial.

Prins PJ, Buga A, Storoschuk K, Buxton JD, Jenkins AK, Eklund CS, Dacey VC, Belitz SE, Sullivan RJ, Gerhart HD, D'Agostino DP, Volek JS, Koutnik AP · Journal of the American Nutrition Association · 2026-03-03

Clinical trial / intervention

40. Ketogenic Diet Reduces Alcohol Consumption and Improves Memory and Sociability in Mice.

Bechard AR, Storie K, Grzeskowiak A, Forcier M, Nunez Y, Brambhatt D, Azurin S, Connell R, Kamel J · Journal of studies on alcohol and drugs · 2025-12-15

Clinical trial / intervention

41. Ketogenic Diet and Exercise Improve Peripheral Neuropathy in a Mouse Model of Metabolic Syndrome.

Eid SA, Jaisil P, Guo K, Hayes JM, Pacut C, Rigan DM, Carter A, Teener SJ, Kim B, Kiriluk C, Lentz W, Miller CM, Webber-Davis I, McQuown H, Jang DG, Patterson A, Koubek EJ, Bridges D, Hur J, Meyer JD, Feldman EL · Diabetes · 2025-11-07

Other

42. Effect of a Ketogenic Diet on Submaximal Exercise Capacity and Efficiency in Runners-Erratum.

Shaw DM, Merien F, Braakhuis A, Maunder E, Dulson DK · Medicine and science in sports and exercise · 2024-10-08

Systematic review / meta-analysis

43. The Effects of Ketogenic Diets and Ketone Supplements on the Aerobic Performance of Endurance Runners: A Systematic Review.

Sun K, Choi YT, Yu CCW, Nelson EAS, Goh J, Dai S, Hui LL · Sports health · 2024-09-04

Randomized clinical trial

44. A Single Night in Hypoxia Either with or without Ketone Ester Ingestion Reduces Sleep Quality without Impacting Next-Day Exercise Performance.

Stalmans M, Tominec D, Robberechts R, Lauriks W, Ramaekers M, Debevec T, Poffé C · Medicine and science in sports and exercise · 2024-11-18

Clinical trial / intervention

45. Ketogenic diet in adult patients with mitochondrial myopathy.

Zweers HEE, Kroesen SH, Beerlink G, Buit E, Gerrits K, Dorhout A, van Wegberg AMJ, Janssen MCH, Wortmann SB, Timmers S, Saris CGJ · Molecular genetics and metabolism · 2024-11-10

Other

46. What do ketogenic dietitians and physicians need? A survey from the KetoCollegeAdvance™ training in United Kingdom.

Kossoff EH, Simpson Z, Fountain J · Epilepsy & behavior : E&B · 2024-10-11

Clinical trial / intervention

47. Ketogenic diet with aerobic exercise can induce fat browning: potential roles of β-hydroxybutyrate.

Kim S, Park DH, Moon S, Gu B, Mantik KEK, Kwak HB, Ryu JK, Kang JH · Frontiers in nutrition · 2024-08-29

Preclinical / mechanistic

48. BETA-HYDROXYBUTYRATE COUNTERACTS THE DELETERIOUS EFFECTS OF A SATURATED HIGH-FAT DIET ON SYNAPTIC AMPA RECEPTORS AND COGNITIVE PERFORMANCE.

Rojas R, Griñán-Ferré C, Castellanos A, Griego E, Martínez M, Navarro-López JD, Jiménez-Díaz L, Rodríguez-Álvarez J, Del Cerro DS, Castillo PE, Pallàs M, Fadó R, Casals N · bioRxiv : the preprint server for biology · 2024-07-22

Other

49. The Liver Circadian Metabolic Homeostasis Influence by Combining Ketogenic Diet with Exercise.

Xu W, Wang Z, Zhang C, Yang W, Fan L, Sun H · Nutrients · 2024-06-27

Other

50. Ketogenic Diets Are Not Beneficial for Athletic Performance: Response to Noakes.

Burke LM, Whitfield J · Medicine and science in sports and exercise · 2024-03-18

Other

51. Ketogenic Diets Are Not Beneficial for Athletic Performance.

Burke LM, Whitfield J · Medicine and science in sports and exercise · 2023-11-22

Other

52. Ketogenic Diets Are Beneficial for Athletic Performance: Response to Burke and Whitfield.

Noakes TD · Medicine and science in sports and exercise · 2023-11-22

Other

53. Ketogenic Diets Are Beneficial for Athletic Performance.

Noakes TD · Medicine and science in sports and exercise · 2023-11-15

Randomized clinical trial

54. Changes in the chronic and postprandial blood lipid profiles of trained competitive cyclists and triathletes following a ketogenic diet: a randomized crossover trial.

Graybeal AJ, Kreutzer A, Moss K, Shah M · BMC sports science, medicine & rehabilitation · 2024-01-16

Preclinical / mechanistic

55. An 8-week ketogenic diet improves exercise endurance and liver antioxidant capacity after weight loss in obese mice.

Wang Y, Dong Y, Zhang Y, Yan J, Ren C, Ma H, Cui Z · Frontiers in nutrition · 2023-12-29

Review

56. Impact of the ketogenic diet on body fat, muscle mass, and exercise performance: a review.

Chung N · Physical activity and nutrition · 2023-12-31

Clinical trial / intervention

57. The effect of a short-term ketogenic diet on exercise efficiency during graded exercise in healthy adults.

Cho W, Jung H, Hong S, Yang HI, Park DH, Suh SH, Lee DH, Choe YS, Kim JY, Lee W, Jeon JY · Journal of the International Society of Sports Nutrition · 2023-10-04

Randomized clinical trial

58. Can a modified ketogenic diet be a nutritional strategy for patients with McArdle disease? Results from a randomized, single-blind, placebo-controlled, cross-over study.

Løkken N, Nielsen MR, Stemmerik MG, Ellerton C, Revsbech KL, Macrae M, Slipsager A, Krett B, Beha GH, Emanuelsson F, van Hall G, Quinlivan R, Vissing J · Clinical nutrition (Edinburgh, Scotland) · 2023-09-20

Review

59. High-fat ketogenic diets and ketone monoester supplements differentially affect substrate metabolism during aerobic exercise.

Margolis LM, Pasiakos SM, Howard EE · American journal of physiology. Cell physiology · 2023-09-18

Other

60. Discrepancy of Beta-Hydroxybutyrate Measurements between a Blood Meter and GC-MS Methods in Healthy Humans.

Holland-Winkler AM, Moore AR, Ansley JK, Fritz NA, Bederman I · Muscles (Basel, Switzerland) · 2023-09-27

Other

61. Nutritional Strategies for Endurance Cyclists - Periodized Nutrition, Ketogenic Diets, and Other Considerations - ERRATUM.

Current sports medicine reports · 2023-09-01

Other

62. EPOtential target for endurance performance: the effect of exogenous ketone supplementation on circulating erythropoietin levels.

Robertson AA, Lynagh BM, Thompson KMA, McCarthy DG · The Journal of physiology · 2023-08-11

Review

63. Nutritional Strategies for Endurance Cyclists - Periodized Nutrition, Ketogenic Diets, and Other Considerations.

Wei RJ, Orbeta L, Hatamiya NS, Chang CJ · Current sports medicine reports · 2023-07-01

Review

64. Ketogenic diets, exercise performance, and training adaptations.

Borszcz FK, Gabiatti MP, de Lucas RD, Hansen F · Current opinion in clinical nutrition and metabolic care · 2023-04-27

Other

65. Ketone Esters and Their Effects on Carbohydrate Metabolism During Exercise.

Gonzalez JT · The Journal of nutrition · 2023-04-11

Randomized clinical trial

66. Metabolic and ruck performance effects of a novel, light-weight, energy-dense ketogenic bar.

Buga A, Crabtree CD, Stoner JT, Decker DD, Robinson BT, Kackley ML, Sapper TN, Buxton JD, D'Agostino DP, McClure TS, Berardi A, Cline S, Fleck T, Krout J, Newby D, Koutnik AP, Volek JS, Prins PJ · Experimental physiology · 2023-03-13

Randomized clinical trial

67. Natural killer cell subset count and antigen-stimulated activation in response to exhaustive running following adaptation to a ketogenic diet.

Shaw DM, Keaney L, Maunder E, Dulson DK · Experimental physiology · 2023-02-26

Randomized clinical trial

68. Different Effects of Cyclical Ketogenic vs. Nutritionally Balanced Reduction Diet on Serum Concentrations of Myokines in Healthy Young Males Undergoing Combined Resistance/Aerobic Training.

Kysel P, Haluzíková D, Pleyerová I, Řezníčková K, Laňková I, Lacinová Z, Havrlantová T, Mráz M, Kasperová BJ, Kovářová V, Thieme L, Trnovská J, Svoboda P, Hubáčková SŠ, Vilikus Z, Haluzík M · Nutrients · 2023-03-31

Review

69. Low carbohydrate high fat ketogenic diets on the exercise crossover point and glucose homeostasis.

Noakes TD, Prins PJ, Volek JS, D'Agostino DP, Koutnik AP · Frontiers in physiology · 2023-03-28

Randomized clinical trial

70. Effect of a four-week isocaloric ketogenic diet on physical performance at very high-altitude: a pilot study.

Chiarello N, Leger B, De Riedmatten M, Rossier MF, Vuistiner P, Duc M, Rapillard A, Allet L · BMC sports science, medicine & rehabilitation · 2023-03-20

Preclinical / mechanistic

71. Effect of ketogenic diet on exercise tolerance and transcriptome of gastrocnemius in mice.

Zhang J, Chen B, Zou K · Open life sciences · 2023-02-23

Randomized clinical trial

72. Chronic and Postprandial Metabolic Responses to a Ketogenic Diet Compared to High-Carbohydrate and Habitual Diets in Trained Competitive Cyclists and Triathletes: A Randomized Crossover Trial.

Graybeal AJ, Kreutzer A, Moss K, Rack P, Augsburger G, Braun-Trocchio R, Willis JL, Shah M · International journal of environmental research and public health · 2023-01-08

Clinical trial / intervention

73. Ketogenic Diet Combined with Moderate Aerobic Exercise Training Ameliorates White Adipose Tissue Mass, Serum Biomarkers, and Hepatic Lipid Metabolism in High-Fat Diet-Induced Obese Mice.

Yan J, Ren C, Dong Y, Wali JA, Song H, Zhang Y, Zhang H, Kou G, Raubenheimer D, Cui Z · Nutrients · 2023-01-03

Other

74. Ketogenic Diets and Mitochondrial Function: Benefits for Aging But Not for Athletes.

Pathak SJ, Baar K · Exercise and sport sciences reviews · 2022-09-16

Review

75. Exogenous Ketone Supplements in Athletic Contexts: Past, Present, and Future.

Evans M, McClure TS, Koutnik AP, Egan B · Sports medicine (Auckland, N.Z.) · 2022-10-10

Randomized clinical trial

76. Does exercise during a ketogenic diet effectively alter appetite sensation, appetite-regulating hormones, and body composition?

Valinejad A, Khodaei K · Experimental biology and medicine (Maywood, N.J.) · 2022-08-03

Clinical trial / intervention

77. Effect of 30 days of ketogenic Mediterranean diet with phytoextracts on athletes' gut microbiome composition.

Mancin L, Amatori S, Caprio M, Sattin E, Bertoldi L, Cenci L, Sisti D, Bianco A, Paoli A · Frontiers in nutrition · 2022-10-25

Systematic review / meta-analysis

78. Effects of the Ketogenic Diet on Muscle Hypertrophy in Resistance-Trained Men and Women: A Systematic Review and Meta-Analysis.

Vargas-Molina S, Gómez-Urquiza JL, García-Romero J, Benítez-Porres J · International journal of environmental research and public health · 2022-10-03

Systematic review / meta-analysis

79. The Effects of Concurrent Training Combined with Low-Carbohydrate High-Fat Ketogenic Diet on Body Composition and Aerobic Performance: A Systematic Review and Meta-Analysis.

Wang Y, Zhou K, Wang V, Bao D, Zhou J · International journal of environmental research and public health · 2022-09-14

Systematic review / meta-analysis

80. Ketogenic therapy for Parkinson's disease: A systematic review and synthesis without meta-analysis of animal and human trials.

Grammatikopoulou MG, Tousinas G, Balodimou C, Anastasilakis DA, Gkiouras K, Dardiotis E, Evangeliou AE, Bogdanos DP, Goulis DG · Maturitas · 2022-06-09

Other

81. Influence of Nutritional Ketosis Achieved through Various Methods on Plasma Concentrations of Brain Derived Neurotropic Factor.

Kackley ML, Buga A, Crabtree CD, Sapper TN, McElroy CA, Focht BC, Kraemer WJ, Volek JS · Brain sciences · 2022-08-27

Clinical trial / intervention

82. Acute Ketone Salts-Caffeine-Taurine-Leucine Supplementation but not Ketone Salts-Taurine-Leucine, Improves Endurance Cycling Performance.

Quinones MD, Lemon PWR · International journal of sport nutrition and exercise metabolism · 2022-02-25

Clinical trial / intervention

83. Ketogenic diets, physical activity and body composition: a review.

Ashtary-Larky D, Bagheri R, Bavi H, Baker JS, Moro T, Mancin L, Paoli A · The British journal of nutrition · 2021-07-12

Preclinical / mechanistic

84. Beta-Hydroxybutyrate Suppresses Hepatic Production of the Ghrelin Receptor Antagonist LEAP2.

Holm S, Husted AS, Skov LJ, Morville TH, Hagemann CA, Jorsal T, Dall M, Jakobsen A, Klein AB, Treebak JT, Knop FK, Schwartz TW, Clemmensen C, Holst B · Endocrinology · 2021-11-29

Clinical trial / intervention

85. The effect of a low carbohydrate ketogenic diet with or without exercise on postpartum weight retention, metabolic profile and physical activity performance in postpartum mice.

Hsu YJ, Huang CC, Lin CI · The Journal of nutritional biochemistry · 2022-01-10

Randomized clinical trial

86. The Ketogenic Diet and Alzheimer's Disease.

Hersant H, Grossberg G · The journal of nutrition, health & aging · 2022-06-19

Randomized clinical trial

87. Ketone Ester Effects on Biomarkers of Brain Metabolism and Cognitive Performance in Cognitively Intact Adults ≥ 55 Years Old. A Study Protocol for a Double-Blinded Randomized Controlled Clinical Trial.

Avgerinos KI, Mullins RJ, Egan JM, Kapogiannis D · The journal of prevention of Alzheimer's disease · 2022-01-31

Systematic review / meta-analysis

88. Effects of resistance training combined with a ketogenic diet on body composition: a systematic review and meta-analysis.

Ashtary-Larky D, Bagheri R, Asbaghi O, Tinsley GM, Kooti W, Abbasnezhad A, Afrisham R, Wong A · Critical reviews in food science and nutrition · 2021-02-24

Randomized clinical trial

89. The Effects of 10-Day Exogenous Ketone Consumption on Repeated Time Trial Running Performances: A Randomized-Control Trial.

Jo E, Silva Ms SC, Auslander PhD AT, Arreglado Ms JP, Elam PhD ML, Osmond Ms AD, Steinberg Ms R, Wong Ms MWH · Journal of dietary supplements · 2020-10-28

Randomized clinical trial

90. Caffeine decreases ammonemia in athletes using a ketogenic diet during prolonged exercise.

Prado E, Magalhães-Neto A, Neto JR, Bassini A, Cameron LC · Nutrition (Burbank, Los Angeles County, Calif.) · 2021-06-02

Randomized clinical trial

91. Autonomic and Perceptual Responses to Induction of a Ketogenic Diet in Free-Living Endurance Athletes: A Randomized, Crossover Trial.

Maunder E, Dulson DK, Shaw DM · International journal of sports physiology and performance · 2021-04-19

Randomized clinical trial

92. Rationale and design of the Diet Restriction and Exercise-induced Adaptations in Metastatic breast cancer (DREAM) study: a 2-arm, parallel-group, phase II, randomized control trial of a short-term, calorie-restricted, and ketogenic diet plus exercise during intravenous chemotherapy versus usual care.

Kirkham AA, King K, Joy AA, Pelletier AB, Mackey JR, Young K, Zhu X, Meza-Junco J, Basi SK, Hiller JP, Brkin T, Michalowski B, Pituskin E, Paterson DI, Courneya KS, Thompson RB, Prado CM · BMC cancer · 2021-10-10

Randomized clinical trial

93. Effects of 30 days of ketogenic diet on body composition, muscle strength, muscle area, metabolism, and performance in semi-professional soccer players.

Antonio Paoli A, Mancin L, Caprio M, Monti E, Narici MV, Cenci L, Piccini F, Pincella M, Grigoletto D, Marcolin G · Journal of the International Society of Sports Nutrition · 2021-09-16

Randomized clinical trial

94. Effects of Combining a Ketogenic Diet with Resistance Training on Body Composition, Strength, and Mechanical Power in Trained Individuals: A Narrative Review.

Valenzuela PL, Castillo-García A, Lucia A, Naclerio F · Nutrients · 2021-09-01

Randomized clinical trial

95. Perceptions of appetite do not match hormonal measures of appetite in trained competitive cyclists and triathletes following a ketogenic diet compared to a high-carbohydrate or habitual diet: A randomized crossover trial.

Graybeal AJ, Kreutzer A, Rack P, Moss K, Augsburger G, Willis JL, Braun-Trocchio R, Shah M · Nutrition research (New York, N.Y.) · 2021-08-12

Randomized clinical trial

96. Effects of a low-carbohydrate ketogenic diet on health parameters in resistance-trained women.

Vargas-Molina S, Carbone L, Romance R, Petro JL, Schoenfeld BJ, Kreider RB, Bonilla DA, Benítez-Porres J · European journal of applied physiology · 2021-05-18

Preclinical / mechanistic

97. The Effects of Fasting or Ketogenic Diet on Endurance Exercise Performance and Metabolism in Female Mice.

Holcomb LE, O'Neill CC, DeWitt EA, Kolwicz SC · Metabolites · 2021-06-18

Systematic review / meta-analysis

98. Body composition changes in physically active individuals consuming ketogenic diets: a systematic review.

Coleman JL, Carrigan CT, Margolis LM · Journal of the International Society of Sports Nutrition · 2021-06-05

Clinical trial / intervention

99. Combined effects of a ketogenic diet and exercise training alter mitochondrial and peroxisomal substrate oxidative capacity in skeletal muscle.

Huang TY, Linden MA, Fuller SE, Goldsmith FR, Simon J, Batdorf HM, Scott MC, Essajee NM, Brown JM, Noland RC · American journal of physiology. Endocrinology and metabolism · 2021-04-12

Other

100. Acute Ketogenic Diet and Ketone Ester Supplementation Impairs Race Walk Performance.

Whitfield J, Burke LM, McKay AKA, Heikura IA, Hall R, Fensham N, Sharma AP · Medicine and science in sports and exercise · 2020-10-08

Systematic review / meta-analysis

101. Influences of Ketogenic Diet on Body Fat Percentage, Respiratory Exchange Rate, and Total Cholesterol in Athletes: A Systematic Review and Meta-Analysis.

Lee HS, Lee J · International journal of environmental research and public health · 2021-03-12

Clinical trial / intervention

102. Is a Four-Week Ketogenic Diet an Effective Nutritional Strategy in CrossFit-Trained Female and Male Athletes?

Durkalec-Michalski K, Nowaczyk PM, Główka N, Ziobrowska A, Podgórski T · Nutrients · 2021-03-06

Other

103. Changes in body composition and substrate utilization after a short-term ketogenic diet in endurance-trained males.

McSwiney FT, Fusco B, McCabe L, Lombard A, Crowley P, Walsh J, Hone M, Egan B · Biology of sport · 2020-08-30

Randomized clinical trial

104. The Effect of Blood Ketone Concentration and Exercise Intensity on Exogenous Ketone Oxidation Rates in Athletes.

Dearlove DJ, Harrison OK, Hodson L, Jefferson A, Clarke K, Cox PJ · Medicine and science in sports and exercise · 2020-09-02

Preclinical / mechanistic

105. A Low-Carbohydrate Ketogenic Diet and Treadmill Training Enhanced Fatty Acid Oxidation Capacity but Did Not Enhance Maximal Exercise Capacity in Mice.

Ma S, Yang J, Tominaga T, Liu C, Suzuki K · Nutrients · 2021-02-13

Systematic review / meta-analysis

106. High-Fat Ketogenic Diets and Physical Performance: A Systematic Review.

Murphy NE, Carrigan CT, Margolis LM · Advances in nutrition (Bethesda, Md.) · 2020-03-02

Randomized clinical trial

107. Effects of Two Months of Very Low Carbohydrate Ketogenic Diet on Body Composition, Muscle Strength, Muscle Area, and Blood Parameters in Competitive Natural Body Builders.

Paoli A, Cenci L, Pompei P, Sahin N, Bianco A, Neri M, Caprio M, Moro T · Nutrients · 2021-01-26

Systematic review / meta-analysis

108. Effects of Combined Exercise and Low Carbohydrate Ketogenic Diet Interventions on Waist Circumference and Triglycerides in Overweight and Obese Individuals: A Systematic Review and Meta-Analysis.

Lee HS, Lee J · International journal of environmental research and public health · 2021-01-19

Preclinical / mechanistic

109. The Safety of Very-long-term Intake of a Ketogenic Diet Containing Medium-chain Triacylglycerols.

Fukazawa A, Karasawa T, Yokota Y, Kondo S, Aoyama T, Terada S · Journal of oleo science · 2021-07-01

Randomized clinical trial

110. Effects of acute nutritional ketosis during exercise in adults with glycogen storage disease type IIIa are phenotype-specific: An investigator-initiated, randomized, crossover study.

Hoogeveen IJ, de Boer F, Boonstra WF, van der Schaaf CJ, Steuerwald U, Sibeijn-Kuiper AJ, Vegter RJK, van der Hoeven JH, Heiner-Fokkema MR, Clarke KC, Cox PJ, Derks TGJ, Jeneson JAL · Journal of inherited metabolic disease · 2020-09-07

Randomized clinical trial

111. Adaptation to a ketogenic diet modulates adaptive and mucosal immune markers in trained male endurance athletes.

Shaw DM, Merien F, Braakhuis A, Keaney L, Dulson DK · Scandinavian journal of medicine & science in sports · 2020-10-05

Other

112. Does a ketogenic diet lower a very high Lp(a)? A striking experiment in a male physician.

Scholl JG · BMJ nutrition, prevention & health · 2020-11-20

Clinical trial / intervention

113. A ketogenic diet combined with exercise alters mitochondrial function in human skeletal muscle while improving metabolic health.

Miller VJ, LaFountain RA, Barnhart E, Sapper TS, Short J, Arnold WD, Hyde PN, Crabtree CD, Kackley ML, Kraemer WJ, Villamena FA, Volek JS · American journal of physiology. Endocrinology and metabolism · 2020-09-28

Randomized clinical trial

114. Effects of Ketogenic Dieting on Body Composition, Strength, Power, and Hormonal Profiles in Resistance Training Men.

Wilson JM, Lowery RP, Roberts MD, Sharp MH, Joy JM, Shields KA, Partl JM, Volek JS, D'Agostino DP · Journal of strength and conditioning research · 2017-04-12

Preclinical / mechanistic

115. High-Intensity Interval Training Attenuates Ketogenic Diet-Induced Liver Fibrosis in Type 2 Diabetic Mice by Ameliorating TGF-β1/Smad Signaling.

Zhang Q, Shen F, Shen W, Xia J, Wang J, Zhao Y, Zhang Z, Sun Y, Qian M, Ding S · Diabetes, metabolic syndrome and obesity : targets and therapy · 2020-11-06

Review

116. The potential of a ketogenic diet to minimize effects of the metabolic fault in glycogen storage disease V and VII.

Reason SL, Godfrey RJ · Current opinion in endocrinology, diabetes, and obesity · 2020-08-11

Randomized clinical trial

117. A Ketone Ester Drink Enhances Endurance Exercise Performance in Parkinson's Disease.

Norwitz NG, Dearlove DJ, Lu M, Clarke K, Dawes H, Hu MT · Frontiers in neuroscience · 2020-09-30

Randomized clinical trial

118. Dose response of a novel exogenous ketone supplement on physiological, perceptual and performance parameters.

Prins PJ, D'Agostino DP, Rogers CQ, Ault DL, Welton GL, Jones DW, Henson SR, Rothfuss TJ, Aiken KG, Hose JL, England EL, Atwell AD, Buxton JD, Koutnik AP · Nutrition & metabolism · 2020-09-29

Review

119. Role of a Ketogenic Diet on Body Composition, Physical Health, Psychosocial Well-Being and Sports Performance in Athletes: A Scoping Review.

Bowler AL, Polman R · Sports (Basel, Switzerland) · 2020-09-23

Randomized clinical trial

120. The Influence of Cyclical Ketogenic Reduction Diet vs. Nutritionally Balanced Reduction Diet on Body Composition, Strength, and Endurance Performance in Healthy Young Males: A Randomized Controlled Trial.

Kysel P, Haluzíková D, Doležalová RP, Laňková I, Lacinová Z, Kasperová BJ, Trnovská J, Hrádková V, Mráz M, Vilikus Z, Haluzík M · Nutrients · 2020-09-16

Other

121. Nutritional Ketosis with Ketogenic Diets or Exogenous Ketones: Features, Convergence, and Divergence.

Poff AM, Koutnik AP, Egan B · Current sports medicine reports · 2020-07-22

Randomized clinical trial

122. Titrating a modified ketogenic diet for patients with McArdle disease: A pilot study.

Løkken N, Hansen KK, Storgaard JH, Ørngreen MC, Quinlivan R, Vissing J · Journal of inherited metabolic disease · 2020-02-24

Randomized clinical trial

123. Nutritional ketosis improves exercise metabolism in patients with very long-chain acyl-CoA dehydrogenase deficiency.

Bleeker JC, Visser G, Clarke K, Ferdinandusse S, de Haan FH, Houtkooper RH, IJlst L, Kok IL, Langeveld M, van der Pol WL, de Sain-van der Velden MGM, Sibeijn-Kuiper A, Takken T, Wanders RJA, van Weeghel M, Wijburg FA, van der Woude LH, Wüst RCI, Cox PJ, Jeneson JAL · Journal of inherited metabolic disease · 2020-02-05

Systematic review / meta-analysis

124. A review of the ketogenic diet for endurance athletes: performance enhancer or placebo effect?

Bailey CP, Hennessy E · Journal of the International Society of Sports Nutrition · 2020-06-22

Randomized clinical trial

125. A Pre-Workout Supplement of Ketone Salts, Caffeine, and Amino Acids Improves High-Intensity Exercise Performance in Keto-Naïve and Keto-Adapted Individuals.

Kackley ML, Short JA, Hyde PN, LaFountain RA, Buga A, Miller VJ, Dickerson RM, Sapper TN, Barnhart EC, Krishnan D, McElroy CA, Maresh CM, Kraemer WJ, Volek JS · Journal of the American College of Nutrition · 2020-04-24

Preclinical / mechanistic

126. Effects of a Ketogenic Diet Containing Medium-Chain Triglycerides and Endurance Training on Metabolic Enzyme Adaptations in Rat Skeletal Muscle.

Fukazawa A, Koike A, Karasawa T, Tsutsui M, Kondo S, Terada S · Nutrients · 2020-04-30

Randomized clinical trial

127. Effects of a ketogenic diet on body composition and strength in trained women.

Vargas-Molina S, Petro JL, Romance R, Kreider RB, Schoenfeld BJ, Bonilla DA, Benítez-Porres J · Journal of the International Society of Sports Nutrition · 2020-04-10

Other

128. Exogenous Ketone Supplementation and Keto-Adaptation for Endurance Performance: Disentangling the Effects of Two Distinct Metabolic States.

Shaw DM, Merien F, Braakhuis A, Maunder E, Dulson DK · Sports medicine (Auckland, N.Z.) · 2019-12-11

Randomized clinical trial

129. Effects of an Exogenous Ketone Supplement on Five-Kilometer Running Performance.

Prins PJ, Koutnik AP, D'Agostino DP, Rogers CQ, Seibert JF, Breckenridge JA, Jackson DS, Ryan EJ, Buxton JD, Ault DL · Journal of human kinetics · 2020-03-31

Clinical trial / intervention

130. Beneficial Effects of Ketogenic Diet on Phosphofructokinase Deficiency (Glycogen Storage Disease Type VII).

Similä ME, Auranen M, Piirilä PL · Frontiers in neurology · 2020-02-04

Other

131. A Short-Term Ketogenic Diet Impairs Markers of Bone Health in Response to Exercise.

Heikura IA, Burke LM, Hawley JA, Ross ML, Garvican-Lewis L, Sharma AP, McKay AKA, Leckey JJ, Welvaert M, McCall L, Ackerman KE · Frontiers in endocrinology · 2020-01-21

Preclinical / mechanistic

132. Ketogenic diet in combination with voluntary exercise impacts markers of hepatic metabolism and oxidative stress in male and female Wistar rats.

Moore MP, Cunningham RP, Kelty TJ, Boccardi LR, Nguyen NY, Booth FW, Rector RS · Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme · 2019-05-22

Other

133. Mystery or method? Evaluating claims of increased energy expenditure during a ketogenic diet.

Hall KD · PloS one · 2019-12-09

Clinical trial / intervention

134. Ketogenic Diet: from the Historical Records to Use in Elite Athletes.

Kaspar MB, Austin K, Huecker M, Sarav M · Current nutrition reports · 2019-11-13

Review

135. Impact Of Ketogenic Diet On Athletes: Current Insights.

McSwiney FT, Doyle L, Plews DJ, Zinn C · Open access journal of sports medicine · 2019-11-15

Other

136. Does ketone ester supplementation really blunt overreaching symptoms during endurance training overload?

Bellinger P · The Journal of physiology · 2019-08-16

Systematic review / meta-analysis

137. [Weight loss and body composition changes through ketogenic diet and physical activity: a methodological and systematic review].

Martín-Moraleda E, Delisle C, Collado Mateo D, Aznar-Lain S · Nutricion hospitalaria · 2019-09-19

Preclinical / mechanistic

138. Exogenous Ketones Lower Blood Glucose Level in Rested and Exercised Rodent Models.

Ari C, Murdun C, Koutnik AP, Goldhagen CR, Rogers C, Park C, Bharwani S, Diamond DM, Kindy MS, D'Agostino DP, Kovács Z · Nutrients · 2019-10-01

Other

139. Extended Ketogenic Diet and Physical Training Intervention in Military Personnel.

Volek JS, LaFountain RA, Dituro P · Military medicine · 2019-06-13

Randomized clinical trial

140. Effect of a Ketogenic Diet on Submaximal Exercise Capacity and Efficiency in Runners.

Shaw DM, Merien F, Braakhuis A, Maunder ED, Dulson DK · Medicine and science in sports and exercise · 2019-04-30

Other

142. Can ketone esters support an appetite to perform and recover?

Cervone DT, Hucik B, Wickham KA · The Journal of physiology · 2019-08-18

Other

143. Novel fueling strategies for exercise performance: Can exogenous ketone esters be the answer to prevent overtraining?

Holmer BJ, Watso JC, Robinson AT · The Journal of physiology · 2019-07-30

Randomized clinical trial

144. Low-Carbohydrate Ketogenic Diets in Male Endurance Athletes Demonstrate Different Micronutrient Contents and Changes in Corpuscular Haemoglobin over 12 Weeks.

McSwiney FT, Doyle L · Sports (Basel, Switzerland) · 2019-08-30

Other

145. Ketone ester supplementation in endurance athletes: a miracle drink or 'spin'?

Korevaar DA, Cohen JF, McInnes MDF · The Journal of physiology · 2019-08-16

Clinical trial / intervention

146. A ketogenic diet for reducing obesity and maintaining capacity for physical activity: hype or hope?

Murphy EA, Jenkins TJ · Current opinion in clinical nutrition and metabolic care · 2019-06-06

Randomized clinical trial

147. Ketone ester supplementation blunts overreaching symptoms during endurance training overload.

Poffé C, Ramaekers M, Van Thienen R, Hespel P · The Journal of physiology · 2019-05-22

Randomized clinical trial

148. Effect of a four-week ketogenic diet on exercise metabolism in CrossFit-trained athletes.

Durkalec-Michalski K, Nowaczyk PM, Siedzik K · Journal of the International Society of Sports Nutrition · 2019-04-05

Other

149. Manuscript Clarification for A Low-Carbohydrate Ketogenic Diet Reduces Body Mass Without Compromising Performance in Powerlifting and Olympic Weightlifting Athletes.

Kendall KL, Haff GG · Journal of strength and conditioning research · 2019-03-26

Randomized clinical trial

150. Low-carbohydrate, ketogenic diet impairs anaerobic exercise performance in exercise-trained women and men: a randomized-sequence crossover trial.

Wroble KA, Trott MN, Schweitzer GG, Rahman RS, Kelly PV, Weiss EP · The Journal of sports medicine and physical fitness · 2018-04-04

Other

151. Chronic Adherence to a Ketogenic Diet Modifies Iron Metabolism in Elite Athletes.

McKay AKA, Peeling P, Pyne DB, Welvaert M, Tee N, Leckey JJ, Sharma AP, Ross MLR, Garvican-Lewis LA, Swinkels DW, Laarakkers CM, Burke LM · Medicine and science in sports and exercise · 2018-10-27

Clinical trial / intervention

152. Effects of Ketone Bodies on Endurance Exercise.

Sansone M, Sansone A, Borrione P, Romanelli F, Di Luigi L, Sgrò P · Current sports medicine reports · 2018-12-12

Preclinical / mechanistic

153. Short-term and long-term ketogenic diet therapy and the addition of exercise have differential impacts on metabolic gene expression in the mouse energy-consuming organs heart and skeletal muscle.

Shimizu K, Saito H, Sumi K, Sakamoto Y, Tachi Y, Iida K · Nutrition research (New York, N.Y.) · 2018-09-19

Randomized clinical trial

154. A Low-Carbohydrate Ketogenic Diet Reduces Body Mass Without Compromising Performance in Powerlifting and Olympic Weightlifting Athletes.

Greene DA, Varley BJ, Hartwig TB, Chapman P, Rigney M · Journal of strength and conditioning research · 2018-10-20

Preclinical / mechanistic

155. An 8-Week Ketogenic Diet Alternated Interleukin-6, Ketolytic and Lipolytic Gene Expression, and Enhanced Exercise Capacity in Mice.

Ma S, Huang Q, Tominaga T, Liu C, Suzuki K · Nutrients · 2018-11-07

Randomized clinical trial

156. Intermittent Running and Cognitive Performance after Ketone Ester Ingestion.

Evans M, Egan B · Medicine and science in sports and exercise · 2018-06-27

Other

157. Guiding Ketogenic Diet with Breath Acetone Sensors.

Güntner AT, Kompalla JF, Landis H, Theodore SJ, Geidl B, Sievi NA, Kohler M, Pratsinis SE, Gerber PA · Sensors (Basel, Switzerland) · 2018-10-28

Preclinical / mechanistic

158. Keto analogues and amino acid supplementation and its effects on ammonaemia during extenuating endurance exercise in ketogenic diet-fed rats.

Ferreira RT, Gonçalves SC, Pedrosa ML, Silva ME, Bassini A, Coelho WS, de Magalhães-Neto AM, Prado ES, Cameron LC · The British journal of nutrition · 2018-08-06

Randomized clinical trial

159. Efficacy of ketogenic diet on body composition during resistance training in trained men: a randomized controlled trial.

Vargas S, Romance R, Petro JL, Bonilla DA, Galancho I, Espinar S, Kreider RB, Benítez-Porres J · Journal of the International Society of Sports Nutrition · 2018-07-09

Randomized clinical trial

160. Exogenous ketone salts do not improve cognitive responses after a high-intensity exercise protocol in healthy college-aged males.

Waldman HS, Basham SA, Price FG, Smith JW, Chander H, Knight AC, Krings BM, McAllister MJ · Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme · 2018-02-16

Preclinical / mechanistic

161. An 8-Week Ketogenic Low Carbohydrate, High Fat Diet Enhanced Exhaustive Exercise Capacity in Mice.

Ma S, Huang Q, Yada K, Liu C, Suzuki K · Nutrients · 2018-05-25

Clinical trial / intervention

162. Treatment of Diabetic Mice with a Combination of Ketogenic Diet and Aerobic Exercise via Modulations of PPARs Gene Programs.

Zhang Q, Xu L, Xia J, Wang D, Qian M, Ding S · PPAR research · 2018-03-20

Other

163. Effects of the Ketogenic diet in overweight divers breathing Enriched Air Nitrox.

Bosco G, Rizzato A, Quartesan S, Camporesi E, Mangar D, Paganini M, Cenci L, Malacrida S, Mrakic-Sposta S, Moretti S, Paoli A · Scientific reports · 2018-02-08

Other

164. The Three-Month Effects of a Ketogenic Diet on Body Composition, Blood Parameters, and Performance Metrics in CrossFit Trainees: A Pilot Study.

Kephart WC, Pledge CD, Roberson PA, Mumford PW, Romero MA, Mobley CB, Martin JS, Young KC, Lowery RP, Wilson JM, Huggins KW, Roberts MD · Sports (Basel, Switzerland) · 2018-01-09

Randomized clinical trial

165. Nutritional ketone salts increase fat oxidation but impair high-intensity exercise performance in healthy adult males.

O'Malley T, Myette-Cote E, Durrer C, Little JP · Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme · 2017-07-27

Randomized clinical trial

166. A Ketone Ester Drink Increases Postexercise Muscle Glycogen Synthesis in Humans.

Holdsworth DA, Cox PJ, Kirk T, Stradling H, Impey SG, Clarke K · Medicine and science in sports and exercise · 2017-04-12

Guideline / consensus

167. Ketogenic diet benefits body composition and well-being but not performance in a pilot case study of New Zealand endurance athletes.

Zinn C, Wood M, Williden M, Chatterton S, Maunder E · Journal of the International Society of Sports Nutrition · 2017-07-12

Randomized clinical trial

168. Intake of a Ketone Ester Drink during Recovery from Exercise Promotes mTORC1 Signaling but Not Glycogen Resynthesis in Human Muscle.

Vandoorne T, De Smet S, Ramaekers M, Van Thienen R, De Bock K, Clarke K, Hespel P · Frontiers in physiology · 2017-05-23

Clinical trial / intervention

169. Muscle PGC-1α is required for long-term systemic and local adaptations to a ketogenic diet in mice.

Schnyder S, Svensson K, Cardel B, Handschin C · American journal of physiology. Endocrinology and metabolism · 2017-02-21

Other

170. Ketone Bodies and Exercise Performance: The Next Magic Bullet or Merely Hype?

Pinckaers PJ, Churchward-Venne TA, Bailey D, van Loon LJ · Sports medicine (Auckland, N.Z.) · 2016-07-20

Other

171. Impact of a 6-week non-energy-restricted ketogenic diet on physical fitness, body composition and biochemical parameters in healthy adults.

Urbain P, Strom L, Morawski L, Wehrle A, Deibert P, Bertz H · Nutrition & metabolism · 2017-02-20

Preclinical / mechanistic

172. A Ketogenic Diet in Rodents Elicits Improved Mitochondrial Adaptations in Response to Resistance Exercise Training Compared to an Isocaloric Western Diet.

Hyatt HW, Kephart WC, Holland AM, Mumford P, Mobley CB, Lowery RP, Roberts MD, Wilson JM, Kavazis AN · Frontiers in physiology · 2016-11-08

Randomized clinical trial

173. Nutritional Ketosis Alters Fuel Preference and Thereby Endurance Performance in Athletes.

Cox PJ, Kirk T, Ashmore T, Willerton K, Evans R, Smith A, Murray AJ, Stubbs B, West J, McLure SW, King MT, Dodd MS, Holloway C, Neubauer S, Drawer S, Veech RL, Griffin JL, Clarke K · Cell metabolism · 2016-07-27

Clinical trial / intervention

174. Effects of a ketogenic diet on adipose tissue, liver, and serum biomarkers in sedentary rats and rats that exercised via resisted voluntary wheel running.

Holland AM, Kephart WC, Mumford PW, Mobley CB, Lowery RP, Shake JJ, Patel RK, Healy JC, McCullough DJ, Kluess HA, Huggins KW, Kavazis AN, Wilson JM, Roberts MD · American journal of physiology. Regulatory, integrative and comparative physiology · 2016-06-29

Preclinical / mechanistic

175. A putative low-carbohydrate ketogenic diet elicits mild nutritional ketosis but does not impair the acute or chronic hypertrophic responses to resistance exercise in rodents.

Roberts MD, Holland AM, Kephart WC, Mobley CB, Mumford PW, Lowery RP, Fox CD, McCloskey AE, Shake JJ, Mesquita P, Patel RK, Martin JS, Young KC, Kavazis AN, Wilson JM · Journal of applied physiology (Bethesda, Md. : 1985) · 2015-12-30

Clinical trial / intervention

176. Fat-Free Mass Changes During Ketogenic Diets and the Potential Role of Resistance Training.

Tinsley GM, Willoughby DS · International journal of sport nutrition and exercise metabolism · 2015-08-12

Other

177. Ketogenic Diets for Fat Loss and Exercise Performance: Benefits and Safety?

Kiens B, Astrup A · Exercise and sport sciences reviews · 2015-04-24

Review

178. The Ketogenic Diet and Sport: A Possible Marriage?

Paoli A, Bianco A, Grimaldi KA · Exercise and sport sciences reviews · 2015-04-24

Other

179. The effects of ketogenic diet on oxidative stress and antioxidative capacity markers of Taekwondo athletes.

Rhyu HS, Cho SY, Roh HT · Journal of exercise rehabilitation · 2014-12-31

Other

180. The effect of weight loss by ketogenic diet on the body composition, performance-related physical fitness factors and cytokines of Taekwondo athletes.

Rhyu HS, Cho SY · Journal of exercise rehabilitation · 2014-10-31

Review

181. Acute nutritional ketosis: implications for exercise performance and metabolism.

Cox PJ, Clarke K · Extreme physiology & medicine · 2014-10-29

Clinical trial / intervention

182. Combinatorial treatment of acute spinal cord injury with ghrelin, ibuprofen, C16, and ketogenic diet does not result in improved histologic or functional outcome.

Streijger F, Lee JH, Duncan GJ, Ng MT, Assinck P, Bhatnagar T, Plunet WT, Tetzlaff W, Kwon BK · Journal of neuroscience research · 2014-03-21

Randomized clinical trial

183. The effects of a ketogenic diet on exercise metabolism and physical performance in off-road cyclists.

Zajac A, Poprzecki S, Maszczyk A, Czuba M, Michalczyk M, Zydek G · Nutrients · 2014-06-27

Preclinical / mechanistic

184. Ketogenic diet improves motor performance but not cognition in two mouse models of Alzheimer's pathology.

Brownlow ML, Benner L, D'Agostino D, Gordon MN, Morgan D · PloS one · 2013-09-12

Other

185. Ketogenic diet does not affect strength performance in elite artistic gymnasts.

Paoli A, Grimaldi K, D'Agostino D, Cenci L, Moro T, Bianco A, Palma A · Journal of the International Society of Sports Nutrition · 2012-07-26

Randomized clinical trial

186. Keto analogue and amino acid supplementation affects the ammonaemia response during exercise under ketogenic conditions.

Prado ES, de Rezende Neto JM, de Almeida RD, Dória de Melo MG, Cameron LC · The British journal of nutrition · 2011-02-16

Clinical trial / intervention

187. Resistance training in overweight women on a ketogenic diet conserved lean body mass while reducing body fat.

Jabekk PT, Moe IA, Meen HD, Tomten SE, Høstmark AT · Nutrition & metabolism · 2010-03-02

Preclinical / mechanistic

188. Maintenance on a ketogenic diet: voluntary exercise, adiposity and neuroendocrine effects.

Kinzig KP, Taylor RJ · International journal of obesity (2005) · 2009-06-09

Preclinical / mechanistic

189. Improvement in motor and exploratory behavior in Rett syndrome mice with restricted ketogenic and standard diets.

Mantis JG, Fritz CL, Marsh J, Heinrichs SC, Seyfried TN · Epilepsy & behavior : E&B · 2009-02-26

Preclinical / mechanistic

190. The effects of a ketogenic diet on behavioral outcome after controlled cortical impact injury in the juvenile and adult rat.

Appelberg KS, Hovda DA, Prins ML · Journal of neurotrauma · 2009-02-24

Other

192. Effect of low-carbohydrate-ketogenic diet on metabolic and hormonal responses to graded exercise in men.

Langfort J, Pilis W, Zarzeczny R, Nazar K, Kaciuba-Uściłko H · Journal of physiology and pharmacology : an official journal of the Polish Physiological Society · 1996-06-01

Other

193. Capacity for moderate exercise in obese subjects after adaptation to a hypocaloric, ketogenic diet.

Phinney SD, Horton ES, Sims EA, Hanson JS, Danforth E, LaGrange BM · The Journal of clinical investigation · 1980-11-01

Randomized clinical trial

194. Acute nutritional ketosis during early recovery from aerobic exercise does not affect skeletal muscle transcriptomic response in humans.

Mosquera-Lopez E, Louis J, Edwards JP, Pugh J, Viggars MR, Owens DJ, Areta JL · European journal of applied physiology · 2025-09-17

Randomized clinical trial

195. Carbohydrate mouth-rinsing does not rescue simulated time trial performance in trained endurance cyclists following a 5-day ketogenic diet.

Guppy G, Brouner J, Spendiff O · Journal of the International Society of Sports Nutrition · 2025-12-12

Review

196. The science of ketogenic supplements for athletes: boosting endurance, efficiency, and energy metabolism.

Siri M, Hosseini EM, Mazhari SA, Jalali P, Soltaninejad K, Raji MA, Yazdekhasti N, Naseri E, Mohammadi A, Maleki MH · Nutrition & metabolism · 2025-12-14

Randomized clinical trial

197. Low-carbohydrate ketogenic diet in Mc Ardle's disease: a single-blinded randomized controlled trial.

Martinuzzi A, Musumeci O, Stefan C, Vinante E, Ferrati A, Perillo C, Pesenti N, Toscano A · Journal of neurology · 2025-10-15

Randomized clinical trial

198. Caffeine enhances performance regardless of fueling strategy; however, high carbohydrate availability is associated with improved training speeds compared with ketogenic diet.

Burke LM, Merrell L, Heikura IA, Civil R, Sharma AP, Leckey JJ, McKay AKA · The British journal of nutrition · 2025-09-18

Preclinical / mechanistic

199. Beta-hydroxybutyrate counteracts the deleterious effects of a saturated high-fat diet on synaptic AMPAR receptors and cognitive performance.

Rojas R, Griñán-Ferré C, Castellanos A, Griego E, Martínez M, de Dios Navarro-López J, Jiménez-Díaz L, Rodríguez-Álvarez J, Soto Del Cerro D, Castillo PE, Pallàs M, Casals N, Fadó R · Molecular metabolism · 2025-07-06

Randomized clinical trial

200. Ketone ester ingestion increases exogenous carbohydrate storage and lowers glycemia during post-exercise recovery: a randomised crossover trial.

Clarke L, Russell SL, Spellanzon B, Maher JL, Betts JA, Gonzalez JT · European journal of nutrition · 2025-08-12

Randomized clinical trial

201. Strategic carbohydrate feeding improves performance in ketogenic trained athletes.

Carpenter M, Brouner J, Spendiff O · Clinical nutrition (Edinburgh, Scotland) · 2025-06-25

Systematic review / meta-analysis

202. The Effects of Ketogenic Diet on Athletic Performance: A Systematic Review.

Nnadozie M, Nnonyelu C, Makanay O, Hong D, Maduka C · Cureus · 2025-06-08

Randomized clinical trial

203. Ketone ester ingestion impairs exercise performance without impacting cognitive function or circulating EPO during acute hypoxic exposure.

Stalmans M, Tominec D, Lauriks W, Robberechts R, Ramaekers M, Debevec T, Poffé C · Journal of applied physiology (Bethesda, Md. : 1985) · 2025-05-02

Systematic review / meta-analysis

204. Database Analysis of Application Areas and Global Trends in Ketogenic Diets from 2019 to 2024.

Assmann M, Albrecht I, Frenser M, Marquardt T, Fischer T · Nutrients · 2025-04-27

Clinical trial / intervention

205. Combined Effects of Ketogenic Diet and Aerobic Exercise on Skeletal Muscle Fiber Remodeling and Metabolic Adaptation in Simulated Microgravity Mice.

Chen J, Li W, Yu L, Zhang B, Li Z, Zou P, Ding B, Dai X, Wang Q · Metabolites · 2025-04-13

Review

206. The Influence of Physical Exercise, Ketogenic Diet, and Time-Restricted Eating on De Novo Lipogenesis: A Narrative Review.

Paoli A · Nutrients · 2025-02-13

Preclinical / mechanistic

207. A ketogenic diet enhances aerobic exercise adaptation and promotes muscle mitochondrial remodeling in hyperglycemic mice.

Pattamaprapanont P, Nava RC, Formato M, Cooney EM, Pinto AP, Alves-Wagner AB, Das A, Guan Y, Lessard SJ · Research square · 2025-01-29

Ophthalmology

Glaucoma Recent peer-reviewed literature

Direct human ketogenic-intervention evidence in glaucoma remains very limited. This section therefore labels the current evidence conservatively.

Editorial review · 2024

1. The Metabolic Shift: Unraveling the Potential of the Ketogenic Diet in Glaucoma Management

Original publication title: The Metabolic Shift: Unraveling the Potential of the Ketogenic Diet in Glaucoma Management

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Preclinical / mechanistic

2. The ketogenic diet and hypoxia promote mitophagy in the context of glaucoma.

Morgan AB, Fan Y, Inman DM · Frontiers in cellular neuroscience · 2024-05-22

Other

3. The Ketogenic Diet: Making a Comeback.

Walczyk T, Wick JY · The Consultant pharmacist : the journal of the American Society of Consultant Pharmacists · 2017-07-14

Preclinical / mechanistic

4. A ketogenic diet may offer neuroprotection in glaucoma and mitochondrial diseases of the optic nerve.

Zarnowski T, Tulidowicz-Bielak M, Kosior-Jarecka E, Zarnowska I, A Turski W, Gasior M · Medical hypothesis, discovery & innovation ophthalmology journal · 2014-03-07

Rare & Genetic Disorders

Down Syndrome Recent peer-reviewed literature

Direct ketogenic evidence in Down syndrome is currently very limited; only the directly relevant case report from the source archive is shown.

Case report · 2023

1. Case report: Ketogenic diet acutely improves cognitive function in patient with Down syndrome and Alzheimer’s disease

Original publication title: Case report: Ketogenic diet acutely improves cognitive function in patient with Down syndrome and Alzheimer’s disease

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Gilbert Syndrome Recent peer-reviewed literature

Source-audited selection from the connected PDF archive. Systematic reviews/meta-analyses and recent human evidence are prioritized when available; sparse areas are explicitly kept sparse.

Case report · 2015

1. Gilbert’s Syndrome Successfully Treated with the Paleolithic Ketogenic Diet

Original publication title: Gilbert’s Syndrome Successfully Treated with the Paleolithic Ketogenic Diet

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Other Clinical Areas

COVID-19 & Metabolism Recent peer-reviewed literature

Evidence is ordered with recent human clinical data first, followed by reviews and mechanistic studies. Indirect COVID nutrition papers were excluded.

Recent human clinical evidence · 2025

1. Clinically Meaningful Improvements in Long COVID With a Ketogenic Metabolic Intervention

Original publication title: Clinically Meaningful Improvements in Long COVID With a Ketogenic Metabolic Intervention

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Review · 2024

2. The potential of ketogenic dietary therapy in the COVID-19 pandemic

Original publication title: The potential of ketogenic dietary therapy in the COVID-19 pandemic

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Hypothesis / translational review

3. Refueling the post-COVID-19 brain: potential role of ketogenic medium-chain triglyceride supplementation

Original publication title: Refueling the post-COVID-19 brain: potential role of ketogenic medium-chain triglyceride supplementation

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Review

4. Ketogenic Diet and Ketone Bodies as Clinical Support for the Treatment of SARS-CoV-2: Review of the Evidence

Original publication title: Ketogenic Diet and Ketone Bodies as Clinical Support for the Treatment of SARS-CoV-2: Review of the Evidence

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Human observational evidence

5. Reduced COVID-19 severity elicited by weight loss from a medically supervised ketogenic diet

Original publication title: Reduced COVID-19 severity elicited by weight loss from a medically supervised ketogenic diet

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Mechanistic human/translational study

6. Impaired ketogenesis ties metabolism to T cell dysfunction in COVID-19

Original publication title: Impaired ketogenesis ties metabolism to T cell dysfunction in COVID-19

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Mechanistic human study

7. Ketone Bodies Improve Human CD8+ Cytotoxic T-Cell Immune Response

Original publication title: Ketone Bodies Improve Human CD8+ Cytotoxic T-Cell Immune Response

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Mechanistic review / hypothesis

8. COVID-19: Proposing a Ketone-Based Metabolic Therapy

Original publication title: COVID-19: Proposing a Ketone-Based Metabolic Therapy

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Review

9. Ketogenic Diet as a Preventive and Supportive Care for COVID-19

Original publication title: Ketogenic Diet as a Preventive and Supportive Care for COVID-19

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Human clinical study

10. Clinical efficacy of eucaloric ketogenic nutrition in COVID-19

Original publication title: Clinical efficacy of eucaloric ketogenic nutrition in COVID-19

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Narrative review

11. Ketogenic Diet for Obese COVID-19 Patients: Is Respiratory Disease a Contraindication? A Narrative Review

Original publication title: Ketogenic Diet for Obese COVID-19 Patients: Is Respiratory Disease a Contraindication? A Narrative Review

Bibliographic record reviewed for inclusion in the curated Scientific Library.

Clinical trial / intervention

12. Telehealth-Based Ketogenic Metabolic Therapy With Lifestyle Interventions for Post-viral Illness: A Research Brief of Patients' Experiences.

Colgan DD, Stadler DD, Grow T, Ruddick M, Weimbs T, Davenport TE, Zwickey H · Journal of patient experience · 2026-07-05

Clinical trial / intervention

13. Designing Nutrition Studies for Long COVID and Related Infection-Associated Chronic Illness: Qualitative Insights From a Patient-Reported Evaluation of Ketogenic Metabolic Therapy.

Colgan DD, Buttolph L, Grow T, Stadler DD, Ruddick M, Davenport TE, Zwickey H · Journal of patient experience · 2026-04-13

Preclinical / mechanistic

14. A ketogenic diet can mitigate SARS-CoV-2 induced systemic reprogramming and inflammation.

Palermo A, Li S, Ten Hoeve J, Chellappa A, Morris A, Dillon B, Ma F, Wang Y, Cao E, Shabane B, Acín-Perez R, Petcherski A, Lusis AJ, Hazen S, Shirihai OS, Pellegrini M, Arumugaswami V, Graeber TG, Deb A · Communications biology · 2023-11-03

Clinical trial / intervention

15. Refueling the post COVID-19 brain: potential role of ketogenic medium chain triglyceride supplementation: an hypothesis.

Juby AG, Cunnane SC, Mager DR · Frontiers in nutrition · 2023-06-21

Other

16. Ketone Bodies Improve Human CD8+ Cytotoxic T-Cell Immune Response During COVID-19 Infection.

Hirschberger S, Gellert L, Effinger D, Muenchhoff M, Herrmann M, Briegel JM, Zwißler B, Kreth S · Frontiers in medicine · 2022-06-16

Clinical trial / intervention

17. Ketogenic Diet for Obese COVID-19 Patients: Is Respiratory Disease a Contraindication? A Narrative Review of the Literature on Ketogenic Diet and Respiratory Function.

Gangitano E, Tozzi R, Mariani S, Lenzi A, Gnessi L, Lubrano C · Frontiers in nutrition · 2021-12-09

Case report / case series

18. A case of prurigo pigmentosa occurring in a patient with psoriasis vulgaris following a ketogenic diet during the COVID-19 pandemic.

Oku A, Nakai K, Tsuruta D · International journal of dermatology · 2021-08-07

Other

19. Challenges faced by people with epilepsy on ketogenic diet therapy and their caregivers during the COVID-19 pandemic in Brazil.

Alencastro Veiga Domingues Carneiro R, Dos Santos Lunardi M, Matheus Uberna Giacomini F, Kurrle Rieger D, Dubois Moreira J, Carina Ribeiro da Silva L, Pereira Brito Sampaio L, Lin K · Epilepsy & behavior : E&B · 2021-07-10

Randomized clinical trial

20. Clinical efficacy of eucaloric ketogenic nutrition in the COVID-19 cytokine storm: A retrospective analysis of mortality and intensive care unit admission.

Sukkar SG, Cogorno L, Pisciotta L, Pasta A, Vena A, Gradaschi R, Dentone C, Guiddo E, Martino E, Beltramini S, Donini LM, Carmisciano L, Sormani MP, Bassetti M, GECOVID Study Group · Nutrition (Burbank, Los Angeles County, Calif.) · 2021-03-07

Preclinical / mechanistic

21. Ketogenic diet restrains aging-induced exacerbation of coronavirus infection in mice.

Ryu S, Shchukina I, Youm YH, Qing H, Hilliard B, Dlugos T, Zhang X, Yasumoto Y, Booth CJ, Fernández-Hernando C, Suárez Y, Khanna K, Horvath TL, Dietrich MO, Artyomov M, Wang A, Dixit VD · eLife · 2021-06-21

Other

22. [Obesity, inflammation and COVID-19: preventive interest of ketogenic diet?].

Charlot A, Boumiza R, Roux M, Zoll J · Biologie aujourd'hui · 2021-08-16

Review

23. The dark side of the spoon - glucose, ketones and COVID-19: a possible role for ketogenic diet?

Paoli A, Gorini S, Caprio M · Journal of translational medicine · 2020-11-20

Other

24. Telemedicine, drug-resistant epilepsy, and ketogenic dietary therapies: A patient survey of a pediatric remote-care program during the COVID-19 pandemic.

Semprino M, Fasulo L, Fortini S, Martorell Molina CI, González L, Ramos PA, Martínez C, Caraballo R · Epilepsy & behavior : E&B · 2020-10-03

Other

25. Comment on: Ketogenic diet therapy provision in the COVID-19 pandemic: Dual-center experience and recommendations.

Ferraris C, Pasca L, Guglielmetti M, Marazzi C, Trentani C, Varesio C, Tagliabue A, De Giorgis V · Epilepsy & behavior : E&B · 2020-08-13

Case report / case series

26. Ketogenic diet therapy provision in the COVID-19 pandemic: Dual-center experience and recommendations.

Kossoff EH, Turner Z, Adams J, Bessone SK, Avallone J, McDonald TJW, Diaz-Arias L, Barron BJ, Vizthum D, Cervenka MC · Epilepsy & behavior : E&B · 2020-05-25

Clinical trial / intervention

27. Clinically Meaningful Improvements in Long COVID Symptoms Following Ketogenic Metabolic Therapy Combined with Lifestyle Interventions-A Clinical Case Report and Review of the Literature.

Colgan DD, Stadler DD, Hope AA, Zwickey H, Davenport TE, Weimbs T · Case reports in clinical medicine · 2025-08-06

Aesthetic Medicine & Body Composition Recent peer-reviewed literature

Only directly relevant publications are displayed. Automated search results are not used as bibliography.

Curated references (2)

Effects of 1-Month Very-Low-Calorie Ketogenic Diet on 24-Hour Energy Metabolism and Body Composition in Women With Obesity

J Clin Endocrinol Metab · 2025 · Prospective clinical study

Six- and Twelve-Month Changes in Body Composition and 24-h Energy Expenditure After a Very Low-Calorie Ketogenic Diet

Obesity · 2026 · Follow-up study

Review

3. Sparing Muscle While Losing Fat: A Narrative Review of Ketogenic Diets and Lean Mass Preservation During Weight Loss.

Caturano A, Mocini E, Titi L, Leva F, Cannavaro D, Tarsitano MG, Conte C · Nutrients · 2026-09-07

Clinical trial / intervention

4. The Ketogenic Diet as Adjunctive Strategy in Cancer Treatment-Therapeutic Benefits and Metabolic Risk Using Breast Cancer as an Example.

Szołtysek J, Szymańska B, Piwowar A · Nutrients · 2026-09-06

Systematic review / meta-analysis

5. Do Ketogenic Diets Produce Greater Weight Loss than Higher-Carbohydrate Diets Under Comparable Prescribed Energy Conditions? A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

Żurawski T, Bartosiewicz A · Nutrients · 2026-08-04

Observational human study

6. Six- and Twelve-Month Changes in Body Composition and 24-h Energy Expenditure After a Very Low-Calorie Ketogenic Diet.

Basolo A, Piaggi P, Angeli V, Fierabracci P, Bologna C, Paolucci G, Salvetti G, Chiovato L, Krakoff J, Landi A, Santini F · Obesity (Silver Spring, Md.) · 2026-06-15

Observational human study

7. Personalized Combination of a Ketogenic Diet and Low-Dose Semaglutide for Cardiometabolic Health: A Retrospective Case Series.

Parker G, Morris MD, Heggie JR, Cooper-Leavitt EF, Clark CJ, Reynolds AP, Smith HA, Wendel CP, Jensen WJ, Morris TJ, Reynolds PR, Bikman BT · Journal of personalized medicine · 2026-06-12

Clinical trial / intervention

8. The effects of ketogenic diet and calorie-restricted diet on metabolic dysfunction-associated steatotic liver disease: a retrospective study.

Sun WJ, Xing LL, Zhao SF, Ying HM · Frontiers in nutrition · 2026-05-05

Clinical trial / intervention

9. Leptin/Adiponectin Ratio as a new multidimensional biomarker in obese patients with liver steatosis undergoing VLEKT: results from a pilot study.

Balestra F, Donghia R, De Luca M, Stabile D, Coletta S, Panzetta G, Palieri R, Di Chito M, De Pergola G, Giannelli G, Pesole PL, Scavo MP · Frontiers in nutrition · 2026-03-20

Randomized clinical trial

10. Immune-modulating effects of energy-restricted ketogenic diet in women with overweight and obesity: KETO-MINOX study.

Drabińska-Fois N, Ogrodowczyk AM, Bauer W, Topolska J, Bączek N, Stenbäck V, Herzig KH, Borowicz-Skoneczny S, Romaszko J · European journal of nutrition · 2026-03-07

Randomized clinical trial

11. Effects of the ketogenic-caloric restricted diet on metabolic endotoxemia and metabolic health in adults with prediabetes: A randomized controlled trial.

Jawamis A, Al-Domi H, Sarayreh NA · Nutrition (Burbank, Los Angeles County, Calif.) · 2026-01-23

Randomized clinical trial

12. Ketogenic diet attenuates high fat diet induced obesity in rats: insights into hepatic and intestinal tissues.

Abo El-Magd NF, Ramadan NM, Hassan YF, Mahmoud AM, Azzam MM, Eraky SM · The Journal of nutritional biochemistry · 2025-12-13

Clinical trial / intervention

13. Ketogenic Diet and Exercise Improve Peripheral Neuropathy in a Mouse Model of Metabolic Syndrome.

Eid SA, Jaisil P, Guo K, Hayes JM, Pacut C, Rigan DM, Carter A, Teener SJ, Kim B, Kiriluk C, Lentz W, Miller CM, Webber-Davis I, McQuown H, Jang DG, Patterson A, Koubek EJ, Bridges D, Hur J, Meyer JD, Feldman EL · Diabetes · 2025-11-07

Clinical trial / intervention

14. The impact of a ketogenic diet on weight loss, metabolism, body composition and quality of life.

Hirschberger S, Effinger D, Yoncheva P, Schmid A, Weis MN, Holdt LM, Teupser D, Kreth S · iScience · 2024-10-30

Clinical trial / intervention

15. Weight loss, changes in body composition and inflammatory status after a very low-energy ketogenic therapy (VLEKT): does gender matter?

Muscogiuri G, Verde L, Frias-Toral E, Reytor-González C, Annunziata G, Proganò M, Savastano S, Simancas-Racines D, Colao A, Barrea L · Journal of translational medicine · 2024-10-19

Review

16. Problems and Opportunities in the use of Bioelectrical Impedance Analysis for Assessing Body Composition During Ketogenic Diets: A Scoping Review.

Paoli A, Campa F · Current obesity reports · 2024-05-27

Randomized clinical trial

17. Effects of a Ketogenic Diet on Body Composition in Healthy, Young, Normal-Weight Women: A Randomized Controlled Feeding Trial.

Burén J, Svensson M, Liv P, Sjödin A · Nutrients · 2024-06-26

Preclinical / mechanistic

18. Role of insulin resistance and leptin in the effect of intermittent feeding with a high-protein ketogenic diet on body composition in rats.

Eyikudamaci G, Ege H, Ensen N, Yelmen N · Nutrition (Burbank, Los Angeles County, Calif.) · 2023-09-07

Clinical trial / intervention

19. Association between ß-Hydroxybutyrate Plasma Concentrations after Hypocaloric Ketogenic Diets and Changes in Body Composition.

Martins C, Nymo S, Aukan MI, Roekenes JA, Coutinho SR, Hunter GR, Gower BA · The Journal of nutrition · 2023-05-12

Preclinical / mechanistic

20. The Effect of the Restrictive Ketogenic Diet on the Body Composition, Haematological and Biochemical Parameters, Oxidative Stress and Advanced Glycation End-Products in Young Wistar Rats with Diet-Induced Obesity.

Drabińska N, Juśkiewicz J, Wiczkowski W · Nutrients · 2022-11-13

Randomized clinical trial

21. Does exercise during a ketogenic diet effectively alter appetite sensation, appetite-regulating hormones, and body composition?

Valinejad A, Khodaei K · Experimental biology and medicine (Maywood, N.J.) · 2022-08-03

Randomized clinical trial

22. Impact of a ketogenic diet intervention during radiotherapy on body composition: V. Final results of the KETOCOMP study for head and neck cancer patients.

Klement RJ, Sweeney RA · Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2022-05-02

Clinical trial / intervention

23. Ketogenic diets, physical activity and body composition: a review.

Ashtary-Larky D, Bagheri R, Bavi H, Baker JS, Moro T, Mancin L, Paoli A · The British journal of nutrition · 2021-07-12

Other

24. Effect of very low-calorie ketogenic diet in combination with omega-3 on inflammation, satiety hormones, body composition, and metabolic markers. A pilot study in class I obese subjects.

Rondanelli M, Perna S, Ilyas Z, Peroni G, Bazire P, Sajuox I, Maugeri R, Nichetti M, Gasparri C · Endocrine · 2021-09-16

Systematic review / meta-analysis

25. Effects of resistance training combined with a ketogenic diet on body composition: a systematic review and meta-analysis.

Ashtary-Larky D, Bagheri R, Asbaghi O, Tinsley GM, Kooti W, Abbasnezhad A, Afrisham R, Wong A · Critical reviews in food science and nutrition · 2021-02-24

Systematic review / meta-analysis

26. The effect of ketogenic diet on body composition and anthropometric measures: A systematic review and meta-analysis of randomized controlled trials.

Amini MR, Aminianfar A, Naghshi S, Larijani B, Esmaillzadeh A · Critical reviews in food science and nutrition · 2021-01-14

Clinical trial / intervention

27. Effects of a Non-Energy-Restricted Ketogenic Diet on Clinical Oral Parameters. An Exploratory Pilot Trial.

Woelber JP, Tennert C, Ernst SF, Vach K, Ratka-Krüger P, Bertz H, Urbain P · Nutrients · 2021-11-25

Randomized clinical trial

28. Effects of 30 days of ketogenic diet on body composition, muscle strength, muscle area, metabolism, and performance in semi-professional soccer players.

Antonio Paoli A, Mancin L, Caprio M, Monti E, Narici MV, Cenci L, Piccini F, Pincella M, Grigoletto D, Marcolin G · Journal of the International Society of Sports Nutrition · 2021-09-16

Randomized clinical trial

29. Effects of Combining a Ketogenic Diet with Resistance Training on Body Composition, Strength, and Mechanical Power in Trained Individuals: A Narrative Review.

Valenzuela PL, Castillo-García A, Lucia A, Naclerio F · Nutrients · 2021-09-01

Clinical trial / intervention

30. Impact of a ketogenic diet intervention during radiotherapy on body composition: IV. Final results of the KETOCOMP study for rectal cancer patients.

Klement RJ, Koebrunner PS, Meyer D, Kanzler S, Sweeney RA · Clinical nutrition (Edinburgh, Scotland) · 2021-05-31

Systematic review / meta-analysis

31. Body composition changes in physically active individuals consuming ketogenic diets: a systematic review.

Coleman JL, Carrigan CT, Margolis LM · Journal of the International Society of Sports Nutrition · 2021-06-05

Clinical trial / intervention

32. Effect of a Free-Living Ketogenic Diet on Feasibility, Satiety, Body Composition, and Metabolic Health in Women: The Grading Level of Optimal Carbohydrate for Women (GLOW) Study.

Saenz C, Hooper S, Orange T, Knight A, Barragan M, Lynch T, Remenapp A, Coyle K, Winters C, Hausenblas H · Journal of the American College of Nutrition · 2021-03-11

Randomized clinical trial

33. A Randomized, Controlled Trial Comparing the Impact of a Low-Calorie Ketogenic vs a Standard Low-Calorie Diet on Fat-Free Mass in Patients Receiving an Elipse™ Intragastric Balloon Treatment.

Schiavo L, De Stefano G, Persico F, Gargiulo S, Di Spirito F, Griguolo G, Petrucciani N, Fontas E, Iannelli A, Pilone V · Obesity surgery · 2020-11-20

Other

34. Changes in body composition and substrate utilization after a short-term ketogenic diet in endurance-trained males.

McSwiney FT, Fusco B, McCabe L, Lombard A, Crowley P, Walsh J, Hone M, Egan B · Biology of sport · 2020-08-30

Randomized clinical trial

35. Effects of Two Months of Very Low Carbohydrate Ketogenic Diet on Body Composition, Muscle Strength, Muscle Area, and Blood Parameters in Competitive Natural Body Builders.

Paoli A, Cenci L, Pompei P, Sahin N, Bianco A, Neri M, Caprio M, Moro T · Nutrients · 2021-01-26

Randomized clinical trial

36. Effects of Ketogenic Dieting on Body Composition, Strength, Power, and Hormonal Profiles in Resistance Training Men.

Wilson JM, Lowery RP, Roberts MD, Sharp MH, Joy JM, Shields KA, Partl JM, Volek JS, D'Agostino DP · Journal of strength and conditioning research · 2017-04-12

Clinical trial / intervention

37. Very low calorie ketogenic diets in overweight and obesity treatment: Effects on anthropometric parameters, body composition, satiety, lipid profile and microbiota.

Di Rosa C, Lattanzi G, Taylor SF, Manfrini S, Khazrai YM · Obesity research & clinical practice · 2020-09-09

Clinical trial / intervention

38. Impact of a ketogenic diet intervention during radiotherapy on body composition: III-final results of the KETOCOMP study for breast cancer patients.

Klement RJ, Champ CE, Kämmerer U, Koebrunner PS, Krage K, Schäfer G, Weigel M, Sweeney RA · Breast cancer research : BCR · 2020-08-20

Other

39. A ketogenic diet exerts beneficial effects on body composition of cancer patients during radiotherapy: An interim analysis of the KETOCOMP study.

Klement RJ, Schäfer G, Sweeney RA · Journal of traditional and complementary medicine · 2019-03-21

Preclinical / mechanistic

40. Male mice placed on a ketogenic diet from postnatal day (P) 21 through adulthood have reduced growth, are hypoactive, show increased freezing in a conditioned fear paradigm, and have spatial learning deficits.

Miles KN, Skelton MR · Brain research · 2020-01-31

Randomized clinical trial

41. Effects of a ketogenic diet on body composition and strength in trained women.

Vargas-Molina S, Petro JL, Romance R, Kreider RB, Schoenfeld BJ, Bonilla DA, Benítez-Porres J · Journal of the International Society of Sports Nutrition · 2020-04-10

Other

42. Energy expenditure and body composition changes after an isocaloric ketogenic diet in overweight and obese men: A secondary analysis of energy expenditure and physical activity.

Friedman MI, Appel S · PloS one · 2019-12-09

Systematic review / meta-analysis

43. [Weight loss and body composition changes through ketogenic diet and physical activity: a methodological and systematic review].

Martín-Moraleda E, Delisle C, Collado Mateo D, Aznar-Lain S · Nutricion hospitalaria · 2019-09-19

Other

44. Effects of a Personalized VLCKD on Body Composition and Resting Energy Expenditure in the Reversal of Diabetes to Prevent Complications.

Romano L, Marchetti M, Gualtieri P, Di Renzo L, Belcastro M, De Santis GL, Perrone MA, De Lorenzo A · Nutrients · 2019-07-04

Clinical trial / intervention

45. Satiating Effect of a Ketogenic Diet and Its Impact on Muscle Improvement and Oxidation State in Multiple Sclerosis Patients.

Benlloch M, López-Rodríguez MM, Cuerda-Ballester M, Drehmer E, Carrera S, Ceron JJ, Tvarijonaviciute A, Chirivella J, Fernández-García D, de la Rubia Ortí JE · Nutrients · 2019-05-23

Randomized clinical trial

46. A Ketogenic Diet Reduces Central Obesity and Serum Insulin in Women with Ovarian or Endometrial Cancer.

Cohen CW, Fontaine KR, Arend RC, Alvarez RD, Leath CA, Huh WK, Bevis KS, Kim KH, Straughn JM, Gower BA · The Journal of nutrition · 2017-11-30

Randomized clinical trial

47. Efficacy of ketogenic diet on body composition during resistance training in trained men: a randomized controlled trial.

Vargas S, Romance R, Petro JL, Bonilla DA, Galancho I, Espinar S, Kreider RB, Benítez-Porres J · Journal of the International Society of Sports Nutrition · 2018-07-09

Other

48. The Three-Month Effects of a Ketogenic Diet on Body Composition, Blood Parameters, and Performance Metrics in CrossFit Trainees: A Pilot Study.

Kephart WC, Pledge CD, Roberson PA, Mumford PW, Romero MA, Mobley CB, Martin JS, Young KC, Lowery RP, Wilson JM, Huggins KW, Roberts MD · Sports (Basel, Switzerland) · 2018-01-09

Randomized clinical trial

49. Efficacy and safety of very-low-calorie ketogenic diet: a double blind randomized crossover study.

Colica C, Merra G, Gasbarrini A, De Lorenzo A, Cioccoloni G, Gualtieri P, Perrone MA, Bernardini S, Bernardo V, Di Renzo L, Marchetti M · European review for medical and pharmacological sciences · 2017-05-25

Other

50. Impact of a 6-week non-energy-restricted ketogenic diet on physical fitness, body composition and biochemical parameters in healthy adults.

Urbain P, Strom L, Morawski L, Wehrle A, Deibert P, Bertz H · Nutrition & metabolism · 2017-02-20

Clinical trial / intervention

51. Body Composition Changes After Very-Low-Calorie Ketogenic Diet in Obesity Evaluated by 3 Standardized Methods.

Gomez-Arbelaez D, Bellido D, Castro AI, Ordoñez-Mayan L, Carreira J, Galban C, Martinez-Olmos MA, Crujeiras AB, Sajoux I, Casanueva FF · The Journal of clinical endocrinology and metabolism · 2016-06-14

Clinical trial / intervention

52. Energy expenditure and body composition changes after an isocaloric ketogenic diet in overweight and obese men.

Hall KD, Chen KY, Guo J, Lam YY, Leibel RL, Mayer LE, Reitman ML, Rosenbaum M, Smith SR, Walsh BT, Ravussin E · The American journal of clinical nutrition · 2016-07-06

Guideline / consensus

53. Impact of a ketogenic diet intervention during radiotherapy on body composition: I. Initial clinical experience with six prospectively studied patients.

Klement RJ, Sweeney RA · BMC research notes · 2016-03-05

Case report / case series

54. Long-term effects of a ketogenic diet on body composition and bone mineralization in GLUT-1 deficiency syndrome: a case series.

Bertoli S, Trentani C, Ferraris C, De Giorgis V, Veggiotti P, Tagliabue A · Nutrition (Burbank, Los Angeles County, Calif.) · 2014-01-29

Preclinical / mechanistic

55. Ketogenic diet-fed rats have increased fat mass and phosphoenolpyruvate carboxykinase activity.

Ribeiro LC, Chittó AL, Müller AP, Rocha JK, Castro da Silva M, Quincozes-Santos A, Nardin P, Rotta LN, Ziegler DR, Gonçalves CA, Da Silva RS, Perry ML, Gottfried C · Molecular nutrition & food research · 2008-07-26

Other

56. The effects of a high-protein, low-fat, ketogenic diet on adolescents with morbid obesity: body composition, blood chemistries, and sleep abnormalities.

Willi SM, Oexmann MJ, Wright NM, Collop NA, Key LL · Pediatrics · 1998-01-17

Clinical trial / intervention

57. Therapeutic effectiveness of low-calorie ketogenic diet on body composition and biochemical parameters in polycystic ovary syndrome - An ıntervention study.

Seven Avuk H, Baş M · Nutricion hospitalaria · 2025-11-13

Clinical trial / intervention

58. A pilot study examining a ketogenic diet as an adjunct therapy in college students with major depressive disorder.

Decker DD, Patel R, Cheavens J, Hayes SM, Whitted W, Lee AJ, Buga A, Robinson BT, Crabtree CD, Kackley ML, Stoner JT, Sapper TN, Chebbi A, Volek JS · Translational psychiatry · 2025-09-10

Clinical trial / intervention

59. Phenotype-Driven Variability in Longitudinal Body Composition Changes After a Very Low-Calorie Ketogenic Intervention: A Machine Learning Cluster Approach.

de la O V, de Cuevillas B, Henkrich M, Vizmanos B, Nuñez-Garcia M, Sajoux I, de Luis D, Martínez JA · Journal of personalized medicine · 2025-06-14

Systematic review / meta-analysis

60. Effects of ketogenic diets on polycystic ovary syndrome: a systematic review and meta-analysis.

Cannarella R, Rubulotta M, Leonardi A, Crafa A, Calvo A, Barbagallo F, La Vignera S, Calogero AE · Reproductive biology and endocrinology : RB&E · 2025-05-20

Clinical trial / intervention

61. Anthropometric Trajectories and Dietary Compliance During a Personalized Ketogenic Program.

García-Gorrita C, Soriano JM, Merino-Torres JF, San Onofre N · Nutrients · 2025-04-27

Other

62. Impact of a Fish-Based Restrictive Ketogenic Diet on Body Composition and Strength Capacity: A Pre-Post Study.

Siedzik K, Góral K, Rodziewicz-Flis E, Olek RA, Ziółkowski W · Nutrients · 2025-04-08

Systematic review / meta-analysis

63. Effects of ketogenic and low-carbohydrate diets on the body composition of adults with overweight or obesity: A systematic review and meta-analysis of randomised controlled trials.

Leung LY, Tam HL, Ho JK · Clinical nutrition (Edinburgh, Scotland) · 2025-01-18

Case report / case series

64. Changes in body composition during weight reduction in obesity. Balance studies comparing effects of fasting and a ketogenic diet.

Benoit FL, Martin RL, Watten RH · Annals of internal medicine · 1965-10-01